|
Name |
Accession |
Description |
Interval |
E-value |
| beta-trefoil_Ricin_CRYBG1 |
cd23464 |
ricin B-type lectin domain, beta-trefoil fold, found in beta/gamma crystallin ... |
1830-1966 |
6.14e-86 |
|
ricin B-type lectin domain, beta-trefoil fold, found in beta/gamma crystallin domain-containing protein 1 (CRYBG1) and similar proteins; CRYBG1, also called absent in melanoma 1 protein (AIM1), may function as a suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton. CRYBG1 belongs to the beta/gamma-crystallin family. It contains a ricin B-type lectin domain at the C-terminus. The ricin B-type lectin domain shows a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. Each subdomain may harbor a sugar-binding pocket.
Pssm-ID: 467342 Cd Length: 137 Bit Score: 276.68 E-value: 6.14e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1830 QKRIYFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQEGCIKCRIAEDCCLTIVGSLVTSGSKLGLALDQ 1909
Cdd:cd23464 1 QKRVYFRLRNKETGCFMSTNGNLDDLKLLRIQVLEDTGSDDQIWVYQDGLIRCRMAEDCCLETVGNLVTAGSKLGLSLEQ 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1566846674 1910 NVDSQFWCMKSDGRIYSKMKPNLVLDVKGGAQYDQNHIILNTVSTEKLTQVWEAMVL 1966
Cdd:cd23464 81 GKDNQFWSITSDGRIYSKLKPDLVLDIKGGQQYDQNHVILNTFDEEKLTQRWEVEIL 137
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1464-1557 |
1.12e-32 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 122.22 E-value: 1.12e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1464 KVVIYEKPSFEGRCMELETEMSSFIMEGGeteettgnnnlpFTSVGSMKVLRGVWVAYEKCGFTGHQYLLEEGEYRDWNA 1543
Cdd:pfam00030 1 KIVLYEKENFQGRSIELTDDCPSLQERGF------------NSRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSD 68
|
90
....*....|....
gi 1566846674 1544 WGGYNGELQSLRPI 1557
Cdd:pfam00030 69 WGAPNDRIGSLRPI 82
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1749-1827 |
1.32e-30 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 116.05 E-value: 1.32e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1749 IILFERENFKGKKIELNAETVNLRSLGFNTQIRSVRVVGGIWVTYEYGNYRGRQFLLSPAEVPNWYEFSA-CRQIGSLRP 1827
Cdd:pfam00030 2 IVLYEKENFQGRSIELTDDCPSLQERGFNSRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSDWGApNDRIGSLRP 81
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1565-1648 |
1.32e-29 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 113.36 E-value: 1.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1565 HMIMYSEKNFgsKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYVLDKGFYTSFEDWGGKNCKISS 1644
Cdd:pfam00030 1 KIVLYEKENF--QGRSIELTDDCPSLQERGFNSRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSDWGAPNDRIGS 78
|
....
gi 1566846674 1645 VQPI 1648
Cdd:pfam00030 79 LRPI 82
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1749-1827 |
3.29e-29 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 112.22 E-value: 3.29e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1749 IILFERENFKGKKIELNAETVNLRSLGFNTQIRSVRVVGGIWVTYEYGNYRGRQFLLSPAEVPNWYEFSA-CRQIGSLRP 1827
Cdd:smart00247 2 ITLYEDENFQGRSYELSDDCPSLQDYGSRDNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQEWGGfNDQISSIRR 81
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1464-1557 |
1.26e-26 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 104.90 E-value: 1.26e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1464 KVVIYEKPSFEGRCMELETEMSSFimeggeteettgNNNLPFTSVGSMKVLRGVWVAYEKCGFTGHQYLLEEGEYRDWNA 1543
Cdd:smart00247 1 KITLYEDENFQGRSYELSDDCPSL------------QDYGSRDNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQE 68
|
90
....*....|....
gi 1566846674 1544 WGGYNGELQSLRPI 1557
Cdd:smart00247 69 WGGFNDQISSIRRI 82
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1661-1740 |
2.78e-26 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 103.73 E-value: 2.78e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1661 QIHLFSEPQFQGQSQSFEETIDQIDDSF---QTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPCLSAMGClPGATLKSL 1737
Cdd:pfam00030 1 KIVLYEKENFQGRSIELTDDCPSLQERGfnsRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSDWGA-PNDRIGSL 79
|
...
gi 1566846674 1738 RFI 1740
Cdd:pfam00030 80 RPI 82
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1369-1450 |
6.53e-26 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 102.96 E-value: 6.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1369 QIDLFTEPEGLGLLNSYFDDTEEMQGFPVMQKTCSIKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEEAYIGSMR 1448
Cdd:pfam00030 1 KIVLYEKENFQGRSIELTDDCPSLQERGFNSRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSDWGAPNDRIGSLR 80
|
..
gi 1566846674 1449 PL 1450
Cdd:pfam00030 81 PI 82
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1565-1648 |
1.15e-23 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 96.42 E-value: 1.15e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1565 HMIMYSEKNFGskGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYVLDKGFYTSFEDWGGKNCKISS 1644
Cdd:smart00247 1 KITLYEDENFQ--GRSYELSDDCPSLQDYGSRDNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQEWGGFNDQISS 78
|
....
gi 1566846674 1645 VQPI 1648
Cdd:smart00247 79 IRRI 82
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1661-1740 |
2.16e-19 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 84.10 E-value: 2.16e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1661 QIHLFSEPQFQGQSQSFEETIDQIDDSF---QTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPCLSAMGCLpGATLKSL 1737
Cdd:smart00247 1 KITLYEDENFQGRSYELSDDCPSLQDYGsrdNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQEWGGF-NDQISSI 79
|
...
gi 1566846674 1738 RFI 1740
Cdd:smart00247 80 RRI 82
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1369-1450 |
8.44e-19 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 82.56 E-value: 8.44e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1369 QIDLFTEPEGLGLLNSYFDDTEEMQGFPVMQKTCSIKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEEAYIGSMR 1448
Cdd:smart00247 1 KITLYEDENFQGRSYELSDDCPSLQDYGSRDNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQEWGGFNDQISSIR 80
|
..
gi 1566846674 1449 PL 1450
Cdd:smart00247 81 RI 82
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
346-990 |
1.30e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 67.27 E-value: 1.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 346 APVACPEPKASSCPRGQPRGEPDRSKP-LSPTKRKGrsrvpEAVP-------------SSPGSGSraPAKESPPKRAPAA 411
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPSRLAPaILPDEPVG-----EPVHprmltwirgleelASDDAGD--PPPPLPPAAPPAA 2563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 412 ADSGEEAGRVVPR--ELTVKSSSLLPEIKPEHKRGPLPhhfdsRGDGGRSRGTGASDAdgLKPRnqfgvgrstvttkvTL 489
Cdd:PHA03247 2564 PDRSVPPPRPAPRpsEPAVTSRARRPDAPPQSARPRAP-----VDDRGDPRGPAPPSP--LPPD--------------TH 2622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 490 PARPKhvelnlktPKNPDSLGNE----HNSFSQPVHKGNTA---NKISLFENKRANSSPRHPDVRNTRNNPPSSKTFVGR 562
Cdd:PHA03247 2623 APDPP--------PPSPSPAANEpdphPPPTVPPPERPRDDpapGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS 2694
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 563 AKlNLAKKAKEMEQPEKKAVSTShqNGLVVKEPSAEGKGTAVPVPREEIRPATrgGEGESTKDQVLRPEPEQSdkldvqt 642
Cdd:PHA03247 2695 LT-SLADPPPPPPTPEPAPHALV--SATPLPPGPAAARQASPALPAAPAPPAV--PAGPATPGGPARPARPPT------- 2762
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 643 dTAYPSHPGPTAlVPVkdselsgeGQPEAADSKGPVlnntsdvaqdiAAICDAREAPPKPqdafSDSQPASAAESARESS 722
Cdd:PHA03247 2763 -TAGPPAPAPPA-APA--------AGPPRRLTRPAV-----------ASLSESRESLPSP----WDPADPPAAVLAPAAA 2817
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 723 LPPSA-PISVDAPQDGCVQVPiCSVPCTALEVSENHNGCVSPVSPHTEKTPISKPgvgeASPPSTPEHSP-ETMGKDCPS 800
Cdd:PHA03247 2818 LPPAAsPAGPLPPPTSAQPTA-PPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSP----AAKPAAPARPPvRRLARPAVS 2892
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 801 KvlvQVRSFVLPVENPQDV-SSQVISESSEVREAQLPSCHSNEPEvvsvTTCVPQHEDAPDT--------SPKDIHHREG 871
Cdd:PHA03247 2893 R---STESFALPPDQPERPpQPQAPPPPQPQPQPPPPPQPQPPPP----PPPRPQPPLAPTTdpagagepSGAVPQPWLG 2965
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 872 HVAQSRPHITQS-GPEKAPPIQSSSGMPQTaefiLTHSPSSR--SHAEGPQRPGQDATSPLTPTRLLNISAGSDNSVLDS 948
Cdd:PHA03247 2966 ALVPGRVAVPRFrVPQPAPSREAPASSTPP----LTGHSLSRvsSWASSLALHEETDPPPVSLKQTLWPPDDTEDSDADS 3041
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 1566846674 949 S--SDMEKF-TEIIKKMDSAVCVPQKKK------KARVPNSPAPHFAMPPI 990
Cdd:PHA03247 3042 LfdSDSERSdLEALDPLPPEPHDPFAHEpdpatpEAGARESPSSQFGPPPL 3092
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1270-1322 |
2.64e-08 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 52.88 E-value: 2.64e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1566846674 1270 KVVIFSEPDVSEECIEVFGDIQDCSS-WRLSPVIVVKVVRGCWILYEKANFEGH 1322
Cdd:pfam00030 1 KIVLYEKENFQGRSIELTDDCPSLQErGFNSRVNSIRVLSGAWVLYEHPNFRGR 54
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1270-1322 |
2.74e-08 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 52.51 E-value: 2.74e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1566846674 1270 KVVIFSEPDVSEECIEVFGD---IQDCSSWRLspVIVVKVVRGCWILYEKANFEGH 1322
Cdd:smart00247 1 KITLYEDENFQGRSYELSDDcpsLQDYGSRDN--VSSVRVESGCWVLYEQPNYRGR 54
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
156-415 |
2.99e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 59.09 E-value: 2.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 156 PArsPGEEALPGAGLQPETARGVSGSPPEEHLVGGVGEAPDGAPGVGAEAGSL----GAPGDAVPPGEPPAQDAEtSRTA 231
Cdd:PRK07003 360 PA--VTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALapkaAAAAAATRAEAPPAAPAP-PATA 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 232 GSVDRAHPTKVLTLDIYLSKTEVAQVDEPASIAPGTDDCEDS---DDMEKRSSGRRSGRRRKSQKSTDSPGADAVAPESA 308
Cdd:PRK07003 437 DRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASapaSDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAA 516
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 309 AK-DEAVFDDEVAPDAAAENCLAERKVKSVqavpdGGAAP----VACPEPKASSCPRGQPRGEPDRSKPLSPTKRKGRSR 383
Cdd:PRK07003 517 SReDAPAAAAPPAPEARPPTPAAAAPAARA-----GGAAAaldvLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPR 591
|
250 260 270
....*....|....*....|....*....|...
gi 1566846674 384 VPEAVPsSPGSGSRAP-AKESPPKRAPAAADSG 415
Cdd:PRK07003 592 VAVQVP-TPRARAATGdAPPNGAARAEQAAESR 623
|
|
| Ricin_B_lectin |
pfam00652 |
Ricin-type beta-trefoil lectin domain; |
1834-1961 |
4.95e-07 |
|
Ricin-type beta-trefoil lectin domain;
Pssm-ID: 395527 [Multi-domain] Cd Length: 126 Bit Score: 50.61 E-value: 4.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1834 YFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDvGADDQIW-IYQEGCIKCRiAEDCCLTIVGSlvTSGSKLGLAL-DQNV 1911
Cdd:pfam00652 2 TGRIRNRASGKCLDVPGGSSAGGPVGLYPCHG-SNGNQLWtLTGDGTIRSV-ASDLCLDVGST--ADGAKVVLWPcHPGN 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1566846674 1912 DSQFWCMKSDGR-IYSKmKPNLVLDVKGGAQyDQNHIILNTVSTEKLTQVW 1961
Cdd:pfam00652 78 GNQRWRYDEDGTqIRNP-QSGKCLDVSGAGT-SNGKVILWTCDSGNPNQQW 126
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
602-989 |
2.82e-06 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 52.27 E-value: 2.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 602 TAVPVPREEI--RPATRGGEGESTKDQVLRPEPEQSDKLDVQTDTAYPShpgPTALVP------VKDSELSGEGQPEAAD 673
Cdd:pfam17823 20 AAPADPRHFVlnKMWNGAGKQNASGDAVPRADNKSSEQ*NFCAATAAPA---PVTLTKgtsaahLNSTEVTAEHTPHGTD 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 674 SKGPVlnnTSDVAQDIAAicdaREAPPKPqdafSDSQPASAAES-ARESSLPPSAPISvdAPQdgcvqVPICSVPCTale 752
Cdd:pfam17823 97 LSEPA---TREGAADGAA----SRALAAA----ASSSPSSAAQSlPAAIAALPSEAFS--APR-----AAACRANAS--- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 753 vsenhngcvspVSPHTEKTPISKPGVGEASP----PSTPEHSPETMGKDCPSKVLVQVRSFVLPVENPQDVSSQVISESS 828
Cdd:pfam17823 156 -----------AAPRAAIAAASAPHAASPAPrtaaSSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAA 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 829 EVREAQLPSChSNEPEVVS--VTTCVPQHEDAPDTSPKDIHHREGHVAQSRPHITQSGPEKAPPIQSSSGMPqtaefilt 906
Cdd:pfam17823 225 GTALAAVGNS-SPAAGTVTaaVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNP-------- 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 907 hSPSSRSHAEGP------QRPGQDATSPLTPTrllnisagsdnsvlDSSSDMEKFTEIIKKMDSAVCVPQKKKKARVPNS 980
Cdd:pfam17823 296 -AAPMGAQAQGPiiqvstDQPVHNTAGEPTPS--------------PSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSA 360
|
410
....*....|..
gi 1566846674 981 ---PAPHFAMPP 989
Cdd:pfam17823 361 spvPVLHTSMIP 372
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
42-235 |
9.14e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.67 E-value: 9.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 42 NSKSASAKVPKTGSEKTKA-QDNQLKATDAGEAGPRQEAEGQPVESCVQATPCDAEQSPCSSINVGVVQQCHSNDSAQLE 120
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPeEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 121 PLQAEGETFPDATTAAKELLHSSPGNRSRQESAETPARSPGEEALPGAGLQPETARGVSGSPPEEHLVGGVGEAPDGAPG 200
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPD 750
|
170 180 190
....*....|....*....|....*....|....*
gi 1566846674 201 VGAEAGSLGAPGDAVPPGEPPAQDAETSRTAGSVD 235
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEM 785
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| beta-trefoil_Ricin_CRYBG1 |
cd23464 |
ricin B-type lectin domain, beta-trefoil fold, found in beta/gamma crystallin ... |
1830-1966 |
6.14e-86 |
|
ricin B-type lectin domain, beta-trefoil fold, found in beta/gamma crystallin domain-containing protein 1 (CRYBG1) and similar proteins; CRYBG1, also called absent in melanoma 1 protein (AIM1), may function as a suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton. CRYBG1 belongs to the beta/gamma-crystallin family. It contains a ricin B-type lectin domain at the C-terminus. The ricin B-type lectin domain shows a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. Each subdomain may harbor a sugar-binding pocket.
Pssm-ID: 467342 Cd Length: 137 Bit Score: 276.68 E-value: 6.14e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1830 QKRIYFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQEGCIKCRIAEDCCLTIVGSLVTSGSKLGLALDQ 1909
Cdd:cd23464 1 QKRVYFRLRNKETGCFMSTNGNLDDLKLLRIQVLEDTGSDDQIWVYQDGLIRCRMAEDCCLETVGNLVTAGSKLGLSLEQ 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1566846674 1910 NVDSQFWCMKSDGRIYSKMKPNLVLDVKGGAQYDQNHIILNTVSTEKLTQVWEAMVL 1966
Cdd:cd23464 81 GKDNQFWSITSDGRIYSKLKPDLVLDIKGGQQYDQNHVILNTFDEEKLTQRWEVEIL 137
|
|
| beta-trefoil_Ricin_CRYBG |
cd23430 |
ricin B-type lectin domain, beta-trefoil fold, found in the beta/gamma crystallin ... |
1833-1965 |
5.13e-73 |
|
ricin B-type lectin domain, beta-trefoil fold, found in the beta/gamma crystallin domain-containing protein (CRYBG) family; The CRYBG family includes three members: CRYBG1, CRYBG2, and CRYBG3/vlAKAP. CRYBG1, also called absent in melanoma 1 protein (AIM1), may function as a suppressor of malignant melanoma. It may exert its effects through interactions with the cytoskeleton. CRYBG2 is also called absent in melanoma 1-like protein (AIM1L). CRYBG3/vlAKAP, also called very large A-kinase anchor protein, is an anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA). It binds to the dimeric RII-alpha regulatory subunit of PKA (PRKAR2A/PRKAR2B). CRYBG proteins belong to the beta/gamma-crystallin family. They all contain a ricin B-type lectin domain with a beta-trefoil fold at the C-terminus. The beta-trefoil fold is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. Each subdomain may harbor a sugar-binding pocket.
Pssm-ID: 467308 [Multi-domain] Cd Length: 133 Bit Score: 239.41 E-value: 5.13e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1833 IYFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQEGCIKCRIAEDCCLTIVGSLVTSGSKLGLALDQNVD 1912
Cdd:cd23430 1 VYFRLRNKATGLFLSVNGNLEDLKLLRVQVMPDVGADDQIWYYQEGLIKCRIAEDCCLTVIGSLVTPGSKVGLWLEQNAD 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1566846674 1913 SQFWCMKSDGRIYSKMKPNLVLDVKGGAQYDQNHIILNTVSTEKLTQVWEAMV 1965
Cdd:cd23430 81 RQFWSLKSDGRIYSKLKPNLVLDVKGGTQYDQNHVILNTPSEEKFTQVWEIMV 133
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1464-1557 |
1.12e-32 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 122.22 E-value: 1.12e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1464 KVVIYEKPSFEGRCMELETEMSSFIMEGGeteettgnnnlpFTSVGSMKVLRGVWVAYEKCGFTGHQYLLEEGEYRDWNA 1543
Cdd:pfam00030 1 KIVLYEKENFQGRSIELTDDCPSLQERGF------------NSRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSD 68
|
90
....*....|....
gi 1566846674 1544 WGGYNGELQSLRPI 1557
Cdd:pfam00030 69 WGAPNDRIGSLRPI 82
|
|
| beta-trefoil_Ricin_vlAKAP |
cd23463 |
ricin B-type lectin domain, beta-trefoil fold, found in very large A-kinase anchor protein ... |
1830-1966 |
2.82e-31 |
|
ricin B-type lectin domain, beta-trefoil fold, found in very large A-kinase anchor protein (vlAKAP) and similar proteins; vlAKAP, also called beta/gamma crystallin domain-containing protein 3 (CRYBG3), is an anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA). It binds to the dimeric RII-alpha regulatory subunit of PKA (PRKAR2A/PRKAR2B). vlAKAP belongs to the beta/gamma-crystallin family. It contains a ricin B-type lectin domain at the C-terminus. The ricin B-type lectin domain shows a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. Each subdomain may harbor a sugar-binding pocket.
Pssm-ID: 467341 Cd Length: 136 Bit Score: 120.24 E-value: 2.82e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1830 QKRIYFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQEGCIKCRiAEDCCLTIVGSLVTSGSKLGLALDQ 1909
Cdd:cd23463 1 QPRVYLRIKNRAQGLYLTTEGNLADPRATSVCVSQYNGKDTQIWYYCRGLLKSK-ANDACLDVIGGKDNPGSKVALWTEH 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1566846674 1910 NVDSQFWCMKSDGRIYSKMKPNLVLDVKGGAQYDQNHIILNTVSTEKLTQVWEAMVL 1966
Cdd:cd23463 80 GKTHQKWRINEDGTISSHLSDDLVLDLKGGNYYDKDHLIVNNPEEDQQTQKWDIELL 136
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1749-1827 |
1.32e-30 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 116.05 E-value: 1.32e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1749 IILFERENFKGKKIELNAETVNLRSLGFNTQIRSVRVVGGIWVTYEYGNYRGRQFLLSPAEVPNWYEFSA-CRQIGSLRP 1827
Cdd:pfam00030 2 IVLYEKENFQGRSIELTDDCPSLQERGFNSRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSDWGApNDRIGSLRP 81
|
|
| beta-trefoil_Ricin_CRYBG2 |
cd23465 |
ricin B-type lectin domain, beta-trefoil fold, found in beta/gamma crystallin ... |
1830-1966 |
2.46e-30 |
|
ricin B-type lectin domain, beta-trefoil fold, found in beta/gamma crystallin domain-containing protein 2 (CRYBG2) and similar proteins; CRYBG2, also called absent in melanoma 1-like protein (AIM1L), is a beta/gamma-crystallin family protein with a ricin B-type lectin domain at the C-terminus. The ricin B-type lectin domain shows a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. Each subdomain may harbor a sugar-binding pocket.
Pssm-ID: 467343 Cd Length: 136 Bit Score: 117.66 E-value: 2.46e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1830 QKRIYFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDVGADDQIWIYQEGCIKCRIAEDCCLTIVGSlVTSGSKLGLALDQ 1909
Cdd:cd23465 1 QRRVYFRLRNRELGLYLAVPDGVEDMKAGRVVVTEQQEGMSHVWFYEDGLLKNQMAPTMSLQVIGP-PDNGAKVVLWSET 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1566846674 1910 NVDSQFWCMKSDGRIYSKMKPNLVLDVKGGAQYDQNHIILNTVSTEKLTQVWEAMVL 1966
Cdd:cd23465 80 RQPRQTWSIQPSGHILSQMFEGMILDVKGGRTYDRDHVVLWEVSEERPSQIWDMEVL 136
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1565-1648 |
1.32e-29 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 113.36 E-value: 1.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1565 HMIMYSEKNFgsKGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYVLDKGFYTSFEDWGGKNCKISS 1644
Cdd:pfam00030 1 KIVLYEKENF--QGRSIELTDDCPSLQERGFNSRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSDWGAPNDRIGS 78
|
....
gi 1566846674 1645 VQPI 1648
Cdd:pfam00030 79 LRPI 82
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1749-1827 |
3.29e-29 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 112.22 E-value: 3.29e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1749 IILFERENFKGKKIELNAETVNLRSLGFNTQIRSVRVVGGIWVTYEYGNYRGRQFLLSPAEVPNWYEFSA-CRQIGSLRP 1827
Cdd:smart00247 2 ITLYEDENFQGRSYELSDDCPSLQDYGSRDNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQEWGGfNDQISSIRR 81
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1464-1557 |
1.26e-26 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 104.90 E-value: 1.26e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1464 KVVIYEKPSFEGRCMELETEMSSFimeggeteettgNNNLPFTSVGSMKVLRGVWVAYEKCGFTGHQYLLEEGEYRDWNA 1543
Cdd:smart00247 1 KITLYEDENFQGRSYELSDDCPSL------------QDYGSRDNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQE 68
|
90
....*....|....
gi 1566846674 1544 WGGYNGELQSLRPI 1557
Cdd:smart00247 69 WGGFNDQISSIRRI 82
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1661-1740 |
2.78e-26 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 103.73 E-value: 2.78e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1661 QIHLFSEPQFQGQSQSFEETIDQIDDSF---QTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPCLSAMGClPGATLKSL 1737
Cdd:pfam00030 1 KIVLYEKENFQGRSIELTDDCPSLQERGfnsRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSDWGA-PNDRIGSL 79
|
...
gi 1566846674 1738 RFI 1740
Cdd:pfam00030 80 RPI 82
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1369-1450 |
6.53e-26 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 102.96 E-value: 6.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1369 QIDLFTEPEGLGLLNSYFDDTEEMQGFPVMQKTCSIKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEEAYIGSMR 1448
Cdd:pfam00030 1 KIVLYEKENFQGRSIELTDDCPSLQERGFNSRVNSIRVLSGAWVLYEHPNFRGRQYVLEPGEYPDWSDWGAPNDRIGSLR 80
|
..
gi 1566846674 1449 PL 1450
Cdd:pfam00030 81 PI 82
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1565-1648 |
1.15e-23 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 96.42 E-value: 1.15e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1565 HMIMYSEKNFGskGSSIDVLGIVANLKETGYGVKTQSINVLSGVWVAYENPDFTGEQYVLDKGFYTSFEDWGGKNCKISS 1644
Cdd:smart00247 1 KITLYEDENFQ--GRSYELSDDCPSLQDYGSRDNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQEWGGFNDQISS 78
|
....
gi 1566846674 1645 VQPI 1648
Cdd:smart00247 79 IRRI 82
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1661-1740 |
2.16e-19 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 84.10 E-value: 2.16e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1661 QIHLFSEPQFQGQSQSFEETIDQIDDSF---QTKSCRVLGGSWVAYDGENFSGNQYVLEEGHYPCLSAMGCLpGATLKSL 1737
Cdd:smart00247 1 KITLYEDENFQGRSYELSDDCPSLQDYGsrdNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQEWGGF-NDQISSI 79
|
...
gi 1566846674 1738 RFI 1740
Cdd:smart00247 80 RRI 82
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1369-1450 |
8.44e-19 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 82.56 E-value: 8.44e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1369 QIDLFTEPEGLGLLNSYFDDTEEMQGFPVMQKTCSIKVHWGTWLIYEEPGFQGVPFILEPGEYPDLSFWDTEEAYIGSMR 1448
Cdd:smart00247 1 KITLYEDENFQGRSYELSDDCPSLQDYGSRDNVSSVRVESGCWVLYEQPNYRGRQYVLEPGEYPDYQEWGGFNDQISSIR 80
|
..
gi 1566846674 1449 PL 1450
Cdd:smart00247 81 RI 82
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
346-990 |
1.30e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 67.27 E-value: 1.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 346 APVACPEPKASSCPRGQPRGEPDRSKP-LSPTKRKGrsrvpEAVP-------------SSPGSGSraPAKESPPKRAPAA 411
Cdd:PHA03247 2491 AAGAAPDPGGGGPPDPDAPPAPSRLAPaILPDEPVG-----EPVHprmltwirgleelASDDAGD--PPPPLPPAAPPAA 2563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 412 ADSGEEAGRVVPR--ELTVKSSSLLPEIKPEHKRGPLPhhfdsRGDGGRSRGTGASDAdgLKPRnqfgvgrstvttkvTL 489
Cdd:PHA03247 2564 PDRSVPPPRPAPRpsEPAVTSRARRPDAPPQSARPRAP-----VDDRGDPRGPAPPSP--LPPD--------------TH 2622
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 490 PARPKhvelnlktPKNPDSLGNE----HNSFSQPVHKGNTA---NKISLFENKRANSSPRHPDVRNTRNNPPSSKTFVGR 562
Cdd:PHA03247 2623 APDPP--------PPSPSPAANEpdphPPPTVPPPERPRDDpapGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS 2694
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 563 AKlNLAKKAKEMEQPEKKAVSTShqNGLVVKEPSAEGKGTAVPVPREEIRPATrgGEGESTKDQVLRPEPEQSdkldvqt 642
Cdd:PHA03247 2695 LT-SLADPPPPPPTPEPAPHALV--SATPLPPGPAAARQASPALPAAPAPPAV--PAGPATPGGPARPARPPT------- 2762
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 643 dTAYPSHPGPTAlVPVkdselsgeGQPEAADSKGPVlnntsdvaqdiAAICDAREAPPKPqdafSDSQPASAAESARESS 722
Cdd:PHA03247 2763 -TAGPPAPAPPA-APA--------AGPPRRLTRPAV-----------ASLSESRESLPSP----WDPADPPAAVLAPAAA 2817
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 723 LPPSA-PISVDAPQDGCVQVPiCSVPCTALEVSENHNGCVSPVSPHTEKTPISKPgvgeASPPSTPEHSP-ETMGKDCPS 800
Cdd:PHA03247 2818 LPPAAsPAGPLPPPTSAQPTA-PPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSP----AAKPAAPARPPvRRLARPAVS 2892
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 801 KvlvQVRSFVLPVENPQDV-SSQVISESSEVREAQLPSCHSNEPEvvsvTTCVPQHEDAPDT--------SPKDIHHREG 871
Cdd:PHA03247 2893 R---STESFALPPDQPERPpQPQAPPPPQPQPQPPPPPQPQPPPP----PPPRPQPPLAPTTdpagagepSGAVPQPWLG 2965
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 872 HVAQSRPHITQS-GPEKAPPIQSSSGMPQTaefiLTHSPSSR--SHAEGPQRPGQDATSPLTPTRLLNISAGSDNSVLDS 948
Cdd:PHA03247 2966 ALVPGRVAVPRFrVPQPAPSREAPASSTPP----LTGHSLSRvsSWASSLALHEETDPPPVSLKQTLWPPDDTEDSDADS 3041
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 1566846674 949 S--SDMEKF-TEIIKKMDSAVCVPQKKK------KARVPNSPAPHFAMPPI 990
Cdd:PHA03247 3042 LfdSDSERSdLEALDPLPPEPHDPFAHEpdpatpEAGARESPSSQFGPPPL 3092
|
|
| Crystall |
pfam00030 |
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity ... |
1270-1322 |
2.64e-08 |
|
Beta/Gamma crystallin; The alignment comprises two Greek key motifs since the similarity between them is very low.
Pssm-ID: 459639 Cd Length: 82 Bit Score: 52.88 E-value: 2.64e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1566846674 1270 KVVIFSEPDVSEECIEVFGDIQDCSS-WRLSPVIVVKVVRGCWILYEKANFEGH 1322
Cdd:pfam00030 1 KIVLYEKENFQGRSIELTDDCPSLQErGFNSRVNSIRVLSGAWVLYEHPNFRGR 54
|
|
| XTALbg |
smart00247 |
Beta/gamma crystallins; Beta/gamma crystallins |
1270-1322 |
2.74e-08 |
|
Beta/gamma crystallins; Beta/gamma crystallins
Pssm-ID: 214583 Cd Length: 82 Bit Score: 52.51 E-value: 2.74e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1566846674 1270 KVVIFSEPDVSEECIEVFGD---IQDCSSWRLspVIVVKVVRGCWILYEKANFEGH 1322
Cdd:smart00247 1 KITLYEDENFQGRSYELSDDcpsLQDYGSRDN--VSSVRVESGCWVLYEQPNYRGR 54
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
156-415 |
2.99e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 59.09 E-value: 2.99e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 156 PArsPGEEALPGAGLQPETARGVSGSPPEEHLVGGVGEAPDGAPGVGAEAGSL----GAPGDAVPPGEPPAQDAEtSRTA 231
Cdd:PRK07003 360 PA--VTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALapkaAAAAAATRAEAPPAAPAP-PATA 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 232 GSVDRAHPTKVLTLDIYLSKTEVAQVDEPASIAPGTDDCEDS---DDMEKRSSGRRSGRRRKSQKSTDSPGADAVAPESA 308
Cdd:PRK07003 437 DRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASapaSDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAA 516
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 309 AK-DEAVFDDEVAPDAAAENCLAERKVKSVqavpdGGAAP----VACPEPKASSCPRGQPRGEPDRSKPLSPTKRKGRSR 383
Cdd:PRK07003 517 SReDAPAAAAPPAPEARPPTPAAAAPAARA-----GGAAAaldvLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPR 591
|
250 260 270
....*....|....*....|....*....|...
gi 1566846674 384 VPEAVPsSPGSGSRAP-AKESPPKRAPAAADSG 415
Cdd:PRK07003 592 VAVQVP-TPRARAATGdAPPNGAARAEQAAESR 623
|
|
| beta-trefoil_Ricin-like |
cd00161 |
ricin B-type lectin domain, beta-trefoil fold; The ricin B-type lectin domain is a ... |
1834-1961 |
9.08e-08 |
|
ricin B-type lectin domain, beta-trefoil fold; The ricin B-type lectin domain is a carbohydrate-binding domain formed from presumed gene triplication. It shows a beta-trefoil fold characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. The ricin B-type lectin domain was originally found in Ricin, which is a legume lectin from the seeds of the castor bean plant, Ricinus communis. It is also found in many carbohydrate-recognition proteins like plant and bacterial AB-toxins, glycosidases, or proteases, which serve diverse functions such as inhibitory toxicity, enzymatic activity, and signal transduction. The ricin B-type lectin domain can be present in one or more copies and has been shown in some instances to bind simple sugars, such as galactose or lactose. The most characteristic, though not completely conserved, sequence feature is the presence of a Q-W pattern. Consequently, the ricin B-type lectin domain has also been referred as the (QxW)3 domain and the three homologous regions as the QxW repeats. A disulfide bond is also conserved in some QxW repeats.
Pssm-ID: 467293 [Multi-domain] Cd Length: 134 Bit Score: 52.76 E-value: 9.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1834 YFRLRNKATGLFMS-TNGNLEDLKllRVQVMEDVGADDQIWIYQE-----GCIKCRiAEDCCLTIVGSLVTSGSKLGLAL 1907
Cdd:cd00161 2 TYRIVNAASGKCLDvAGGSTANGA--PVQQWTCNGGANQQWTLTPvgdgyYTIRNV-ASGKCLDVAGGSTANGANVQQWT 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1566846674 1908 DQNVDSQFWCMKSDG----RIYSKmKPNLVLDVKGGAQYDQNHIILNTVSTEKlTQVW 1961
Cdd:cd00161 79 CNGGDNQQWRLEPVGdgyyRIVNK-HSGKCLDVSGGSTANGANVQQWTCNGGA-NQQW 134
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
78-462 |
9.39e-08 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 57.49 E-value: 9.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 78 EAEGQPVESCVQATPCDAEQSPCS-SINVGVVQQCHSNDSAQLEPLQAEgETFPDATTAAKELLHSSPGNRSRqesAETP 156
Cdd:PHA03307 14 AAEGGEFFPRPPATPGDAADDLLSgSQGQLVSDSAELAAVTVVAGAAAC-DRFEPPTGPPPGPGTEAPANESR---STPT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 157 ARSPGEEALPGAGLQPETARGVSGSPPEEHLVGGVGEAPDGAPGVGAEAGSLGAPGDAVPPGEPPAQDAETSRTAGSVDR 236
Cdd:PHA03307 90 WSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASS 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 237 AHPTKVLTLDIYLSKTEVAQVDEPASIAP---GTDDCEDSDDMEKRSSGRRSGRRRKSQKSTDSPGA-DAVAPESAAKDE 312
Cdd:PHA03307 170 RQAALPLSSPEETARAPSSPPAEPPPSTPpaaASPRPPRRSSPISASASSPAPAPGRSAADDAGASSsDSSSSESSGCGW 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 313 AVFDDEVAPDAAAENCLAERKVKSVQAVPDGGAAPVACPEPKASSCPRGQPRGEPDRSKPLSPTKRKGRSRVPEAVPSSP 392
Cdd:PHA03307 250 GPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 393 GSGSRAPAKESP-----------PKRAPAAADSGEEAGRVVPRELTVKSSSLLPEIKPEHKRGPLPHHFDSRGDGGRSRG 461
Cdd:PHA03307 330 SSSSESSRGAAVspgpspsrspsPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPA 409
|
.
gi 1566846674 462 T 462
Cdd:PHA03307 410 G 410
|
|
| beta-trefoil_Ricin_GllA-1 |
cd23454 |
GllA-1 domain, beta-trefoil fold, found in Mucor circinelloides Gellins and similar proteins; ... |
1834-1962 |
9.50e-08 |
|
GllA-1 domain, beta-trefoil fold, found in Mucor circinelloides Gellins and similar proteins; Gellin proteins act as central effectors of wound-induced protoplasmic gelation. They possess ten related N-terminal beta-trefoil domains (Gll-1 to Gll-10) that contribute to distinct gelation-related activities. The beta-trefoil domains show low sequence similarity to members of the functionally diverse ricin B lectin domain family. They are characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. Each subdomain bears a potential sugar binding site. Gellin from M. circinelloides has been called GellinA (also known as GllA). The model corresponds to GllA-1 domain, which is a remote family member of the ricin B-type lectin domain.
Pssm-ID: 467332 [Multi-domain] Cd Length: 136 Bit Score: 52.70 E-value: 9.50e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1834 YFRLRNKATGLFMSTNGNLEDLK---LLRVQVMEDVgaDDQIWIYQEGCIkCRIAEDCCLTIVGSLVTSGSKLGL---AL 1907
Cdd:cd23454 2 WFFIKSSSNGLVLDVEHGSLKSGakvVLAPLKTKDY--ESQLWRYDDGYL-VNKASGLVLDIQGGVVKSGTRLVQspkKP 78
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1566846674 1908 DQNVDSQFWCMKSDGRIYSKMKPNLVLDVKGGAQYDQNHIILNTVSTEK--LTQVWE 1962
Cdd:cd23454 79 SKDANNQRWGLTADGYIYLLSNPSLVLGIKGNETREGARVILQERKLQKdaLNQRWT 135
|
|
| Ricin_B_lectin |
pfam00652 |
Ricin-type beta-trefoil lectin domain; |
1834-1961 |
4.95e-07 |
|
Ricin-type beta-trefoil lectin domain;
Pssm-ID: 395527 [Multi-domain] Cd Length: 126 Bit Score: 50.61 E-value: 4.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1834 YFRLRNKATGLFMSTNGNLEDLKLLRVQVMEDvGADDQIW-IYQEGCIKCRiAEDCCLTIVGSlvTSGSKLGLAL-DQNV 1911
Cdd:pfam00652 2 TGRIRNRASGKCLDVPGGSSAGGPVGLYPCHG-SNGNQLWtLTGDGTIRSV-ASDLCLDVGST--ADGAKVVLWPcHPGN 77
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1566846674 1912 DSQFWCMKSDGR-IYSKmKPNLVLDVKGGAQyDQNHIILNTVSTEKLTQVW 1961
Cdd:pfam00652 78 GNQRWRYDEDGTqIRNP-QSGKCLDVSGAGT-SNGKVILWTCDSGNPNQQW 126
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
602-989 |
2.82e-06 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 52.27 E-value: 2.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 602 TAVPVPREEI--RPATRGGEGESTKDQVLRPEPEQSDKLDVQTDTAYPShpgPTALVP------VKDSELSGEGQPEAAD 673
Cdd:pfam17823 20 AAPADPRHFVlnKMWNGAGKQNASGDAVPRADNKSSEQ*NFCAATAAPA---PVTLTKgtsaahLNSTEVTAEHTPHGTD 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 674 SKGPVlnnTSDVAQDIAAicdaREAPPKPqdafSDSQPASAAES-ARESSLPPSAPISvdAPQdgcvqVPICSVPCTale 752
Cdd:pfam17823 97 LSEPA---TREGAADGAA----SRALAAA----ASSSPSSAAQSlPAAIAALPSEAFS--APR-----AAACRANAS--- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 753 vsenhngcvspVSPHTEKTPISKPGVGEASP----PSTPEHSPETMGKDCPSKVLVQVRSFVLPVENPQDVSSQVISESS 828
Cdd:pfam17823 156 -----------AAPRAAIAAASAPHAASPAPrtaaSSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAA 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 829 EVREAQLPSChSNEPEVVS--VTTCVPQHEDAPDTSPKDIHHREGHVAQSRPHITQSGPEKAPPIQSSSGMPqtaefilt 906
Cdd:pfam17823 225 GTALAAVGNS-SPAAGTVTaaVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNP-------- 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 907 hSPSSRSHAEGP------QRPGQDATSPLTPTrllnisagsdnsvlDSSSDMEKFTEIIKKMDSAVCVPQKKKKARVPNS 980
Cdd:pfam17823 296 -AAPMGAQAQGPiiqvstDQPVHNTAGEPTPS--------------PSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSA 360
|
410
....*....|..
gi 1566846674 981 ---PAPHFAMPP 989
Cdd:pfam17823 361 spvPVLHTSMIP 372
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
60-423 |
1.11e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 50.75 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 60 AQDNQLKATDAGEAGPRQEAEGQPVescvqATPCDAEQSPCSSINVGVVQQCHSNDSAQLEPLQAEGETFPDATTAAKEl 139
Cdd:PRK07764 408 AAPAPAAAAPAAAAAPAPAAAPQPA-----PAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPA- 481
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 140 lhsspgnrSRQESAETPARSPGEEALPGAGLQPETARGVSGSPPEehLVGGVGEAPDG-APGVGAEAGSLGAPGDAVPPG 218
Cdd:PRK07764 482 --------PAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPE--ILAAVPKRSRKtWAILLPEATVLGVRGDTLVLG 551
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 219 EPPAQDAETSRTAGSVD--RAHPTKVLTLDIylskTEVAQVDEPASIAPGTDDCEDSDDMEKRSSGRRSGRRRKSQKSTD 296
Cdd:PRK07764 552 FSTGGLARRFASPGNAEvlVTALAEELGGDW----QVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAP 627
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 297 SPGADAVAPESAAKDEAVFDDEVAPDAAAENCLAERKVKSVQAVPDGGAAPVAcPEPKASSCPRGQPRGEPDRS--KPLS 374
Cdd:PRK07764 628 APAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAA-PPPAPAPAAPAAPAGAAPAQpaPAPA 706
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1566846674 375 PTKRKGRSRVPEAVPSSPGSGSRAPAKES----PPKRAPAAADSGEEAGRVVP 423
Cdd:PRK07764 707 ATPPAGQADDPAAQPPQAAQGASAPSPAAddpvPLPPEPDDPPDPAGAPAQPP 759
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
198-412 |
1.96e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 49.85 E-value: 1.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 198 APGVGAeAGSLGAPGDAVPPGEPPAQDAETSRTAGSVDRAHPTKVltldiylsKTEVAQVDEPASIAPGtddcedsdDME 277
Cdd:PRK07003 359 EPAVTG-GGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAV--------TGAAGAALAPKAAAAA--------AAT 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 278 KRSSGRRSGRRRKSQKSTDSPGADAVAPESAAKDEAVfDDEVAPDAAAENCLAERkvksVQAVPDGGAAPVACPEPKASS 357
Cdd:PRK07003 422 RAEAPPAAPAPPATADRGDDAADGDAPVPAKANARAS-ADSRCDERDAQPPADSG----SASAPASDAPPDAAFEPAPRA 496
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1566846674 358 CPrGQPRGEPDRSKPLSPTKRKGRSRVPEAVPSSPGSGSRAPAKESPPKRAPAAA 412
Cdd:PRK07003 497 AA-PSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAA 550
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
111-277 |
4.19e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 48.55 E-value: 4.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 111 CHSNDSAQLEPLQAegetfPDATTAAKELLHSSPGNRSRQESAETPARSPGEEALPGAG--LQPETARGVSGSPPEEhlv 188
Cdd:PRK08691 366 CDANAVIENTELQS-----PSAQTAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEGktAGPVSNQENNDVPPWE--- 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 189 ggvgEAPD----GAPGVGAEAGSLGAPGDAVPPGE-----PPAQDAETSRTAGSVDRAHPTKVLTLDIYLsKTEVAQVDE 259
Cdd:PRK08691 438 ----DAPDeaqtAAGTAQTSAKSIQTASEAETPPEnqvskNKAADNETDAPLSEVPSENPIQATPNDEAV-ETETFAHEA 512
|
170 180
....*....|....*....|..
gi 1566846674 260 PASIAPG----TDDCEDSDDME 277
Cdd:PRK08691 513 PAEPFYGygfpDNDCPPEDGAE 534
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
142-733 |
5.15e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.78 E-value: 5.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 142 SSPGNRSRQESAETPA-----RSPGEEALPGAGLQPETArgvsgSPPEEHlvggvgeAPDGAPGVGAEAGSLGAPGDAVP 216
Cdd:PHA03247 2578 SEPAVTSRARRPDAPPqsarpRAPVDDRGDPRGPAPPSP-----LPPDTH-------APDPPPPSPSPAANEPDPHPPPT 2645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 217 PGEPPaqdaeTSRTAGSVDRAHPTKVLTldiylSKTEVAQVDEP----------ASIAPGTDDCEDSDdmekrssgrrsg 286
Cdd:PHA03247 2646 VPPPE-----RPRDDPAPGRVSRPRRAR-----RLGRAAQASSPpqrprrraarPTVGSLTSLADPPP------------ 2703
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 287 rrrksQKSTDSPGADAVAPESAAKdeavfddeVAPDAAAENCLAERKVKSVQAVPDGGAAPVACPEPKASSCPRGQPRGE 366
Cdd:PHA03247 2704 -----PPPTPEPAPHALVSATPLP--------PGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPA 2770
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 367 PDRSKPLSPTKRKGRSRVPEAVPSSPGSGS-RAPAKESPPKRAPAAADSGEEAgrvvPRELTVKSSSLLPeIKPEHKRGP 445
Cdd:PHA03247 2771 PPAAPAAGPPRRLTRPAVASLSESRESLPSpWDPADPPAAVLAPAAALPPAAS----PAGPLPPPTSAQP-TAPPPPPGP 2845
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 446 LPhhfdsrgdggRSRGTGASDADGlKPRNQFGVGRSTVtTKVTLPARPKHVELNLKTPKNPDSlgnehnSFSQPVHKGNT 525
Cdd:PHA03247 2846 PP----------PSLPLGGSVAPG-GDVRRRPPSRSPA-AKPAAPARPPVRRLARPAVSRSTE------SFALPPDQPER 2907
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 526 ANKISLFENKRANSSPRHPDVRNTRNNPPssktfvGRAKLNLAKKAKEMEQPEKKAVSTSHQNGLVVKepsaegkgTAVP 605
Cdd:PHA03247 2908 PPQPQAPPPPQPQPQPPPPPQPQPPPPPP------PRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVP--------GRVA 2973
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 606 VPREEIRPA--TRGGEGESTKDQVLRPEPEQSD-----KLDVQTDtaypshPGPTALVpvkdSELSGEGQPEAADSKGPV 678
Cdd:PHA03247 2974 VPRFRVPQPapSREAPASSTPPLTGHSLSRVSSwasslALHEETD------PPPVSLK----QTLWPPDDTEDSDADSLF 3043
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 679 LNNTSDVaqDIAAIcDAReaPPKPQDAFSDS-QPASAAESARESSL----PPsaPISVDA 733
Cdd:PHA03247 3044 DSDSERS--DLEAL-DPL--PPEPHDPFAHEpDPATPEAGARESPSsqfgPP--PLSANA 3096
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
53-439 |
8.74e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.86 E-value: 8.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 53 TGSEKTKAQDNQLKATDAGEAGPRQEAEGQPVESCVQATPcDAEQSPCSSINVGVVQQCHSNDSAqlEPLQAEGETFPDA 132
Cdd:PHA03307 72 PPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGP-SSPDPPPPTPPPASPPPSPAPDLS--EMLRPVGSPGPPP 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 133 TtaakellHSSPGNRSRQESAETPARSPGEEALPgAGLQPETARGVSGSPPEEHLVGGVGEAPDGAPGVGAEAGSlgapg 212
Cdd:PHA03307 149 A-------ASPPAAGASPAAVASDAASSRQAALP-LSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISA----- 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 213 DAVPPGEPPAQDAETSRTAGSVDRAHPTkvlTLDIYLSKTEVAQVDEPASIAPGTDDCEDSDDMEKRSSGRRSGRRRKSQ 292
Cdd:PHA03307 216 SASSPAPAPGRSAADDAGASSSDSSSSE---SSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPR 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 293 KSTDSP-----GADAVAPESAAKDEAVFDDEVAPDAAAENCLAERKvKSVQAVPDGGAAPVACPEPKASSCPRGQPRGEP 367
Cdd:PHA03307 293 ERSPSPspsspGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRG-AAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRP 371
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1566846674 368 DRSKPL------SPTKRKGRSRVPEAVPSSPGSGSRApakESPPKRAPAAADSGEEAGRVVPRELTVkSSSLLPEIKP 439
Cdd:PHA03307 372 SRAPSSpaasagRPTRRRARAAVAGRARRRDATGRFP---AGRPRPSPLDAGAASGAFYARYPLLTP-SGEPWPGSPP 445
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
42-235 |
9.14e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.67 E-value: 9.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 42 NSKSASAKVPKTGSEKTKA-QDNQLKATDAGEAGPRQEAEGQPVESCVQATPCDAEQSPCSSINVGVVQQCHSNDSAQLE 120
Cdd:PRK07764 591 APGAAGGEGPPAPASSGPPeEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWP 670
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 121 PLQAEGETFPDATTAAKELLHSSPGNRSRQESAETPARSPGEEALPGAGLQPETARGVSGSPPEEHLVGGVGEAPDGAPG 200
Cdd:PRK07764 671 AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPD 750
|
170 180 190
....*....|....*....|....*....|....*
gi 1566846674 201 VGAEAGSLGAPGDAVPPGEPPAQDAETSRTAGSVD 235
Cdd:PRK07764 751 PAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEM 785
|
|
| beta-trefoil_Ricin_HA17-like |
cd23445 |
ricin B-type lectin domain, beta-trefoil fold, found in Clostridium botulinum hemagglutinating ... |
1860-1950 |
1.73e-04 |
|
ricin B-type lectin domain, beta-trefoil fold, found in Clostridium botulinum hemagglutinating proteins, HA17 and HA33, and similar proteins; The subfamily includes Clostridium botulinum hemagglutinating proteins HA17 and HA33, Lysinibacillus sphaericus mosquitocidal toxin (MTX) and Pieris brassicae pierisin. The hemagglutinin (HA) component of the progenitor toxin protects the structural integrity of the neurotoxin. It may increase internalization of the neurotoxin into the bloodstream of the host. The hemagglutinin complex, composed of HA-70 (also known as HA3), HA-33 (also known as HA1) and HA-17 (also known as HA2), agglutinates erythrocytes, whereas the individual components do not. HA-33 is involved in recognition of cell-surface carbohydrates. HA-17 and HA-70 are involved in paracellular barrier disruption by E-cadherin binding. MTX acts as an ADP-ribosyl transferase. Pierisin, also called NAD--DNA ADP-ribosyltransferase, pierisin-2, or pierisin-B, catalyzes the ADP ribosylation of double-stranded DNA by targeting the N2 amino group of dG residues. It induces apoptosis in a range of human cell lines. Members of this subfamily contain at least one ricin B-type lectin domain with a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry.
Pssm-ID: 467323 [Multi-domain] Cd Length: 133 Bit Score: 43.46 E-value: 1.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1860 VQVMEDVGADDQIWI---------YQegcIKCRIAEDCCLTIVGSlvtSGSKLGLALDQNVDSQFWCMK--SDGR--IYS 1926
Cdd:cd23445 24 VVLWDNNGGNNQKWRfeydsgknaYQ---IKNLDNTNLVLAWNSS---SSNNVFASTNTSKDEQYWKLEeaGDGYyiIKN 97
|
90 100
....*....|....*....|....
gi 1566846674 1927 KMKPNLVLDVKGGAQYDQNHIILN 1950
Cdd:cd23445 98 YADPNLVLDVEGSNTANGTNIIVY 121
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
149-428 |
1.84e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.86 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 149 RQESAETPARspGEEALP--------GAGLQPETARGVSG--SPPEEHLVGGVGEAPDGAPGVGAEAGSLGAPGDAVPPG 218
Cdd:PHA03247 240 RRVVISHPLR--GDIAAPapppvvgeGADRAPETARGATGppPPPEAAAPNGAAAPPDGVWGAALAGAPLALPAPPDPPP 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 219 EPPAQDAETsrtAGSVDRA--------HPTKVLTLDiyLSKTEVAQVDEPASIapgtddcedsDDMEKRSSGRRSGRRRK 290
Cdd:PHA03247 318 PAPAGDAEE---EDDEDGAmevvsplpRPRQHYPLG--FPKRRRPTWTPPSSL----------EDLSAGRHHPKRASLPT 382
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 291 SQKSTDSPGADAVAPESAAkdeavfDDEVAPDAAAEnclaerkvksvQAVPDGGAAPVACPEPKASSCPRGQPRGEPDRS 370
Cdd:PHA03247 383 RKRRSARHAATPFARGPGG------DDQTRPAAPVP-----------ASVPTPAPTPVPASAPPPPATPLPSAEPGSDDG 445
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1566846674 371 KPLSPTKRKGRSRVPEAVPSSPGSGSRA--PAKESPPKRAPAAA---------DSGEEAGRVVPRELTV 428
Cdd:PHA03247 446 PAPPPERQPPAPATEPAPDDPDDATRKAldALRERRPPEPPGADlaellgrhpDTAGTVVRLAAREAAI 514
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
345-490 |
3.26e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 45.83 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 345 AAPVACPEPKASSCPRGQPRGEPDRSKPlsPTKRKGRSRVPEAVPSS---PGSGSRAPAKESPPKRAPAAADSGEEAGRV 421
Cdd:PHA03378 719 AATGRARPPAAAPGRARPPAAAPGRARP--PAAAPGRARPPAAAPGRarpPAAAPGAPTPQPPPQAPPAPQQRPRGAPTP 796
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1566846674 422 VPRELTVKSSSLLPEIKPEHKRGPLPHHFDSRGDGGRSRGTGASD---------ADGLKPRNQFGVGRSTVTTKVTLP 490
Cdd:PHA03378 797 QPPPQAGPTSMQLMPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKkpaalerqaAAGPTPSPGSGTSDKIVQAPVFYP 874
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
295-468 |
3.44e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 45.64 E-value: 3.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 295 TDSPGADAVAPESAAKDEAVFDDEVAPDAAAENCLAERKVKSVQAVPDGGAAPVACPEPKASSCPRGQ---PRGEPDRSK 371
Cdd:PRK12323 400 AAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAgprPVAAAAAAA 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 372 PLSPTKRKGRSRVPEAVPS----SPGSGSRAPAKESPPKRAPAAADSGEEAGRVVPRELTVKSSSLLPEIKPEHKRGPLP 447
Cdd:PRK12323 480 PARAAPAAAPAPADDDPPPweelPPEFASPAPAQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEP 559
|
170 180
....*....|....*....|.
gi 1566846674 448 HHFDSRGDGGRSRGTGASDAD 468
Cdd:PRK12323 560 VVAPRPPRASASGLPDMFDGD 580
|
|
| beta-trefoil_Ricin_SCDase_rpt2 |
cd23500 |
second ricin B-type lectin domain, beta-trefoil fold, found in Shewanella algae sphingolipid ... |
1834-1949 |
4.33e-04 |
|
second ricin B-type lectin domain, beta-trefoil fold, found in Shewanella algae sphingolipid ceramide N-deacylase (SCDase) and similar proteins; SCDase (EC 3.5.1.69) is an enzyme which hydrolyzes the N-acyl linkage between fatty acid and sphingosine in ceramide of various glycosphingolipids and sphingomyelin. Shewanella algae SCDase contains two ricin B-type lectin domains at its C-terminus. The ricin B-type lectin domain shows a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. Each subdomain may harbor a sugar-binding pocket. The model corresponds to the second lectin domain.
Pssm-ID: 467378 [Multi-domain] Cd Length: 128 Bit Score: 42.07 E-value: 4.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1834 YFRLRNKATGLFMS-TNGNLEDLKLLRVQVMEdvGADDQIWIY--QEGCIKCRIAEDCCLTIVGSLVTSGSKLGLA-LDQ 1909
Cdd:cd23500 2 WTTYRSKRSGKCLSaANGSQLNGSLVQLDACH--ASAGQLWYFdpKKGTIRSALDGNKCLAIPGGNTGNHTQLQLAdCDA 79
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1566846674 1910 NVDSQFWcMKSDGRIYSKMKPNLVLDVKGGAqyDQNHIIL 1949
Cdd:cd23500 80 SNPAQQF-NYDGGVFRSRLNSNQVIDASGGS--DGSELIL 116
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
600-933 |
4.33e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.55 E-value: 4.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 600 KGTAVPVPREEIRPATRGGEGESTKDQVLRPEPEQSDKLDVQTDTAYPSHPGPTALvPVKDSELSGEGQPEAADSKGPVL 679
Cdd:PHA03307 50 LAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGS-PTPPGPSSPDPPPPTPPPASPPP 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 680 NNTSDVA--QDIAAICDAREAPPKPQDAFSDSQPASAAESARESSLPPSAPISvdapqdgcvqvpicSVPCtalevsenh 757
Cdd:PHA03307 129 SPAPDLSemLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEE--------------TARA--------- 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 758 ngcvsPVSPHTEKtPISKPGvGEASPPSTPEHSPETMGKDCPSKVLVQVRSFvlpvENPQDVSSQVISESSEVREAQLPS 837
Cdd:PHA03307 186 -----PSSPPAEP-PPSTPP-AAASPRPPRRSSPISASASSPAPAPGRSAAD----DAGASSSDSSSSESSGCGWGPENE 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 838 CHSNEPEVVSVTTCVPQHE-------DAPDTSPKD-IHHREGHVAQSRPHitQSGPEKAPPIQSSSGMPQTAEfilTHSP 909
Cdd:PHA03307 255 CPLPRPAPITLPTRIWEASgwngpssRPGPASSSSsPRERSPSPSPSSPG--SGPAPSSPRASSSSSSSRESS---SSST 329
|
330 340
....*....|....*....|....*.
gi 1566846674 910 SSRSHAEGPQ--RPGQDATSPLTPTR 933
Cdd:PHA03307 330 SSSSESSRGAavSPGPSPSRSPSPSR 355
|
|
| beta-trefoil_Ricin_SCDase |
cd23456 |
ricin B-type lectin domain, beta-trefoil fold, found in Shewanella algae sphingolipid ceramide ... |
1834-1941 |
4.77e-04 |
|
ricin B-type lectin domain, beta-trefoil fold, found in Shewanella algae sphingolipid ceramide N-deacylase (SCDase) and similar proteins; SCDase (EC 3.5.1.69) is an enzyme which hydrolyzes the N-acyl linkage between fatty acid and sphingosine in ceramide of various glycosphingolipids and sphingomyelin. Shewanella algae SCDase contains two ricin B-type lectin domains at its C-terminus. The ricin B-type lectin domain shows a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. Each subdomain may harbor a sugar-binding pocket.
Pssm-ID: 467334 [Multi-domain] Cd Length: 122 Bit Score: 41.96 E-value: 4.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1834 YFRLRNKATGLFMSTNGNleDLKLLRVQVMEDVGADDQIWIYQE-GCIKCRIAEDCCLTiVGSLVTSGSKLGLALDQNVD 1912
Cdd:cd23456 2 YFQLKSQASGLCLDVSGG--ATNGANVVVYDCNNSNSQKWYYDAtGRLHSKANPGKCLD-AGGENSNGANVVLWACNDSA 78
|
90 100
....*....|....*....|....*....
gi 1566846674 1913 SQFWcMKSDGRIYSKMKPNLVLDVKGGAQ 1941
Cdd:cd23456 79 NQRW-DFDGNFIRSRNNTNLALDAYGSQG 106
|
|
| beta-trefoil_Ricin_EW29-like |
cd23449 |
ricin B-type lectin domain, beta-trefoil fold, found in Lumbricus terrestris 29-kDa ... |
1834-1939 |
8.96e-04 |
|
ricin B-type lectin domain, beta-trefoil fold, found in Lumbricus terrestris 29-kDa galactose-binding lectin (EW29) and similar proteins; EW29 is a galactose-binding lectin from the earthworm Lumbricus terrestris. It contains two ricin B-type lectin domains with a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. The second ricin B-type lectin domain may harbor two sugar-binding pockets in subdomains alpha and gamma. EW29 uses these two sugar-binding sites for its function as a single domain-type hemagglutinin.
Pssm-ID: 467327 [Multi-domain] Cd Length: 128 Bit Score: 41.12 E-value: 8.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1834 YFRLRNKATGLFMS-TNGNLEDLKLLRVQVMEDVGADDQIWiYQ---EGCIKCRiAEDCCLTIVGS--LVTSgsklglAL 1907
Cdd:cd23449 2 YFYIKSKLNGKVLDvEGANAKPGAKVIMWEKKGGAEDNQLW-YEdevTGTIRSK-LNDFCLDASGDkgLILN------PY 73
|
90 100 110
....*....|....*....|....*....|..
gi 1566846674 1908 DQNVDSQFWCMkSDGRIYSKMKPNLVLDVKGG 1939
Cdd:cd23449 74 DPSNPKQQWKI-SGNKIQNRSNPDNVLDIKGG 104
|
|
| beta-trefoil_Ricin_DCDC1 |
cd23427 |
ricin B-type lectin domain, beta-trefoil fold, found in doublecortin domain-containing protein ... |
1829-1964 |
1.41e-03 |
|
ricin B-type lectin domain, beta-trefoil fold, found in doublecortin domain-containing protein 1 (DCDC1) and similar proteins; DCDC1, also called doublecortin domain-containing 5 protein (DCDC5), is a microtubule-binding protein which plays an important role in mediating dynein-dependent transport of RAB8A-positive vesicles to the midbody during cytokinesis. In addition to doublecortin-like domains, DCDC1 may also contain a ricin B-type lectin domain in the middle region. The ricin B-type lectin domain shows a beta-trefoil fold, which is characterized by 12 beta strands folded into three similar trefoil subdomains (alpha, beta, and gamma) associated to give an overall structure with pseudo-3-fold symmetry. Each subdomain may harbor a putative sugar-binding pocket.
Pssm-ID: 467305 Cd Length: 146 Bit Score: 41.14 E-value: 1.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 1829 AQKRIYFRLRNKAtGLFMSTNGNLEDLKllRVQVMEDVGAddQIWIYQEGCIKCRIAEDCCLTIVGSLVTSGSKLGLAlD 1908
Cdd:cd23427 1 DQIRQYCALRNPE-DLVLEVSGPLVAGS--KLIVNKCVLL--QQFVFEDGFISCCSNPNLVLGVQGSELGRGAEVVLV-K 74
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1566846674 1909 QNVD--SQFWCMKSDGRIYSKMKPNLVLDVK----------GGAQYDQNHIILNTVSTEKL---TQVWEAM 1964
Cdd:cd23427 75 KKPDdiNQRWILREDGHIMSKPNYDLVLTVSmpsttpgdssSPLSYIGCAVILQKYKGYSYgraNQKWHWD 145
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
298-467 |
1.47e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 43.68 E-value: 1.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 298 PGADAVAPESAAKDEAVFDDEVAPDAAAENCLAERKVKSVQAVPDGGAAPVACPEPKASSCPRGQPRGEPDRSKPLSPTK 377
Cdd:PRK07003 377 AGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANAR 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 378 RKGRSRVPE--AVPSSPGSGSRAPAKESPP----KRAPAAADSGEEAGRVVPRELTVKSSSLLPEIKPEHKRGPLPHHFD 451
Cdd:PRK07003 457 ASADSRCDErdAQPPADSGSASAPASDAPPdaafEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPT 536
|
170
....*....|....*.
gi 1566846674 452 SRGDGGRSRGTGASDA 467
Cdd:PRK07003 537 PAAAAPAARAGGAAAA 552
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
67-242 |
1.59e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.44 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 67 ATDAGEAGPRQEAEGQPVESCVQATPCDAEQSPCSSINVGVVQQCHSNDSAQLEPLQAEGETFPDATTAAKELLHSSPGN 146
Cdd:PRK07764 628 APAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAA 707
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 147 RSRQESAETPARSPGEEALPGAGLQPETARGVSgSPPEEHLVGGVGEAPDG--APGVGAEAGSLGAPGDAVPPGEPPAQD 224
Cdd:PRK07764 708 TPPAGQADDPAAQPPQAAQGASAPSPAADDPVP-LPPEPDDPPDPAGAPAQppPPPAPAPAAAPAAAPPPSPPSEEEEMA 786
|
170
....*....|....*...
gi 1566846674 225 AETSRTAGSVDRAHPTKV 242
Cdd:PRK07764 787 EDDAPSMDDEDRRDAEEV 804
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
668-878 |
3.05e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 42.61 E-value: 3.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 668 QPEAADSKGPVlnnTSDVAQDIAAICDAREAPPKPQD----------AFSDSQPASAAESARESSLPPSAPiSVDAPQDG 737
Cdd:PLN03209 332 ESDAADGPKPV---PTKPVTPEAPSPPIEEEPPQPKAvvprplspytAYEDLKPPTSPIPTPPSSSPASSK-SVDAVAKP 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 738 CVQVPIcSVPCTALEVSENHNGCVS-----PVSPHT---EKTPISKPGVGEASPPSTPEHSPETMGKDCPSKVLVQVRSF 809
Cdd:PLN03209 408 AEPDVV-PSPGSASNVPEVEPAQVEakktrPLSPYAryeDLKPPTSPSPTAPTGVSPSVSSTSSVPAVPDTAPATAATDA 486
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 810 VLP-VENPQDVSSQVISESSEVREAQLPSCHSNEPEVVSVTTCVPQHEDAPDTSPKDihhrEGHVAQSRP 878
Cdd:PLN03209 487 AAPpPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALAD----EQHHAQPKP 552
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
297-425 |
3.29e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 42.56 E-value: 3.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 297 SPGADAVAPESAAKDEAVFDDEVAPDAAAENCLAERKVKSVQAVPDGGAAPVA-CPEPKASSCPRGQPRGEPDRSKPlsP 375
Cdd:PRK12323 373 GPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARrSPAPEALAAARQASARGPGGAPA--P 450
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 1566846674 376 TKRKGRSRVPEAVPSSPGSGSRAPAKESPPKRAPAAADSGEEAGRVVPRE 425
Cdd:PRK12323 451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWE 500
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
157-494 |
3.36e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.47 E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 157 ARSPGEEALPGAglqpetargVSGSPPEehLVGGVGEAPDGAPGVGAEAGSLGAPGDAVPPGEPPAQDAETSRTAGSVDr 236
Cdd:PHA03307 24 PPATPGDAADDL---------LSGSQGQ--LVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWS- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 237 ahptkvltldiyLSKTEVAQVDEPASIAPGTDDCEDSddmekrssgrrsgrrRKSQKSTDSPGADAVAPESAAKDEAVFD 316
Cdd:PHA03307 92 ------------LSTLAPASPAREGSPTPPGPSSPDP---------------PPPTPPPASPPPSPAPDLSEMLRPVGSP 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 317 DEVAPDAAAENCLAERKVKSVQAVPDGGA-------APVACPEPKASSCP----------RGQPRGEPDRSKPLSPTKRK 379
Cdd:PHA03307 145 GPPPAASPPAAGASPAAVASDAASSRQAAlplsspeETARAPSSPPAEPPpstppaaaspRPPRRSSPISASASSPAPAP 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 380 GRSRVPEAVPSSPGSGS------------RAPAKESPPKRAPAAADSGEEAGRVVPRELTVKSSS----LLPEIKPEHKR 443
Cdd:PHA03307 225 GRSAADDAGASSSDSSSsessgcgwgpenECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSspreRSPSPSPSSPG 304
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 1566846674 444 GPL---PHHFDSRGDGGRSRGTGASDADGLKPRNQfGVGRSTVTTKVTLPARPK 494
Cdd:PHA03307 305 SGPapsSPRASSSSSSSRESSSSSTSSSSESSRGA-AVSPGPSPSRSPSPSRPP 357
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
131-326 |
3.86e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 42.28 E-value: 3.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 131 DATTAAKELLHSSPGNRSR---QESAETPARSPGEEALPGAGLQPETARGVSGSPPEEHLVGGVGEAPDGAPGVGAEAGS 207
Cdd:PRK07764 596 GGEGPPAPASSGPPEEAARpaaPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGG 675
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 208 lGAPGDAVPPGEPPAQDAETSRTAGSVDRAHPTKVLTLDIYLSKTEVAQVDEPASIAPGTDDCEDSDDMEKRSSGRRSGR 287
Cdd:PRK07764 676 -AAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGA 754
|
170 180 190
....*....|....*....|....*....|....*....
gi 1566846674 288 RRKSQKSTDSPGADAVAPESAAKDEAvfDDEVAPDAAAE 326
Cdd:PRK07764 755 PAQPPPPPAPAPAAAPAAAPPPSPPS--EEEEMAEDDAP 791
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
319-435 |
4.56e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.14 E-value: 4.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 319 VAPDAAAENCLAERKVKSVQAVPDGGAAPVACPEPKAS-SCPRGQPRGEPDRSKPLSPtKRKGRSRVPEAVPSSPGSGSR 397
Cdd:PRK07003 340 LAPDEYAGFTMTLLRMLAFEPAVTGGGAPGGGVPARVAgAVPAPGARAAAAVGASAVP-AVTAVTGAAGAALAPKAAAAA 418
|
90 100 110
....*....|....*....|....*....|....*...
gi 1566846674 398 APAKESPPKRAPAAADSGEEAGRVVPRELTVKSSSLLP 435
Cdd:PRK07003 419 AATRAEAPPAAPAPPATADRGDDAADGDAPVPAKANAR 456
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
306-420 |
8.04e-03 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 40.94 E-value: 8.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1566846674 306 ESAAKDEAVFDDEVAPDAAAENCLAERKVKSVQAVPDGGAAPVACPEPK--ASSCPRGQPRGEPDRSKPLSPTKRKGRsr 383
Cdd:PRK12373 199 EEAGKARYNASKALAEDIGDTVKRIDGTEVPLLAPWQGDAAPVPPSEAArpKSADAETNAALKTPATAPKAAAKNAKA-- 276
|
90 100 110
....*....|....*....|....*....|....*..
gi 1566846674 384 vPEAVPSSPGSGSRAPAKESPPKRAPAAADSGEEAGR 420
Cdd:PRK12373 277 -PEAQPVSGTAAAEPAPKEAAKAAAAAAKPALEDKPR 312
|
|
| Inhibitor_I36 |
pfam03995 |
Peptidase inhibitor family I36; This domain is currently only found in a small set of S. ... |
1751-1801 |
9.26e-03 |
|
Peptidase inhibitor family I36; This domain is currently only found in a small set of S. coelicolor secreted proteins. There are four conserved cysteines that probably form two disulphide bonds. Proteins 2SCK31.15C and SCO3675 also have probable beta-propellers at their C-termini. This family includes Swiss:P01077 a known peptidase inhibitor of known structure. This protein has a crystallin like fold pfam00030 and is distantly related by sequence. It is not known whether other members of this family are peptidase inhibitors.
Pssm-ID: 427638 Cd Length: 69 Bit Score: 36.59 E-value: 9.26e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1566846674 1751 LFERENFKGKKIELNAeTVNLRSLGFNTQIRSVRVVGGIWVT-YEYGNYRGR 1801
Cdd:pfam03995 15 LWSGANGTGRMAELSG-SDALVGAGMNDKARSVWNRTGSWVTvYTDANYGGR 65
|
|
| |
