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Conserved domains on  [gi|1488192453|ref|NP_001353522|]
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serine/arginine repetitive matrix protein 1 isoform 18 [Homo sapiens]

Protein Classification

PWI domain-containing protein( domain architecture ID 10478549)

PWI domain-containing protein may function as a splicing factor; similar to Homo sapiens serine/arginine repetitive matrix protein 1 that is involved in numerous pre-mRNA processing events

CATH:  1.20.1390.10
Gene Ontology:  GO:0006397|GO:0003676
PubMed:  10322432|12600940
SCOP:  4000671

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.67e-12

PWI domain;


:

Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.67e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1488192453   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 331-660 1.84e-06

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.86  E-value: 1.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  331 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEDKGGKMAAADSVQQRRQYRRQNQQSSS 410
Cdd:PHA03247  2615 SPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS 2694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  411 DSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRMQMG-------KRWQSPVTKSGRRRRSPSPP 483
Cdd:PHA03247  2695 LTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGpatpggpARPARPPTTAGPPAPAPPAA 2774

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  484 PTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP--- 560
Cdd:PHA03247  2775 PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlgg 2854

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  561 ---PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRkgSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSS 637
Cdd:PHA03247  2855 svaPGGDVRRRPPSRSPAAKPAAPARPPVRRLAR--PAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP 2932

                          330       340
                   ....*....|....*....|...
gi 1488192453  638 PQRRQSPSPSTRPIRRVSRTPEP 660
Cdd:PHA03247  2933 PPPPPRPQPPLAPTTDPAGAGEP 2955
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.67e-12

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.67e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1488192453   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03247 PHA03247
large tegument protein UL36; Provisional
 331-660 1.84e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.86  E-value: 1.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  331 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEDKGGKMAAADSVQQRRQYRRQNQQSSS 410
Cdd:PHA03247  2615 SPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS 2694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  411 DSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRMQMG-------KRWQSPVTKSGRRRRSPSPP 483
Cdd:PHA03247  2695 LTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGpatpggpARPARPPTTAGPPAPAPPAA 2774

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  484 PTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP--- 560
Cdd:PHA03247  2775 PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlgg 2854

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  561 ---PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRkgSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSS 637
Cdd:PHA03247  2855 svaPGGDVRRRPPSRSPAAKPAAPARPPVRRLAR--PAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP 2932

                          330       340
                   ....*....|....*....|...
gi 1488192453  638 PQRRQSPSPSTRPIRRVSRTPEP 660
Cdd:PHA03247  2933 PPPPPRPQPPLAPTTDPAGAGEP 2955
PWI smart00311
PWI, domain in splicing factors;
1-32 2.24e-04

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 40.41  E-value: 2.24e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1488192453    1 MMQINLTGFLNgknAREFMGELWPLLLSAQEN 32
Cdd:smart00311  46 LLQINLTGFED---AEEFVDKLWRLLIFELKN 74
PI3K_1B_p101 pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific ...
 548-632 4.14e-04

Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IB PI3K, p110gamma, is mainly activated by seven-transmembrane G-protein-coupled receptors (GPCRs), through its regulatory subunit p101 and G-protein beta-gamma subunits.


Pssm-ID: 463109  Cd Length: 860  Bit Score: 43.90  E-value: 4.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 548 PPPPKRRASPSPPPKRRVSHSP--------PPKqrsSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 619
Cdd:pfam10486 394 SSSSPRAEKPREKSKKKSRSRLsqriyrlfKPK---SPLVLRRAKSLGNPEAKDLIPVRSKRSNSLPQQVLLRSLEPPPL 470

                          90
                  ....*....|...
gi 1488192453 620 APQTSSSPPPVRR 632
Cdd:pfam10486 471 PPLSALRHVCFRR 483
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.67e-12

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.67e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1488192453   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03247 PHA03247
large tegument protein UL36; Provisional
 331-660 1.84e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 51.86  E-value: 1.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  331 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEDKGGKMAAADSVQQRRQYRRQNQQSSS 410
Cdd:PHA03247  2615 SPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS 2694

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  411 DSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRMQMG-------KRWQSPVTKSGRRRRSPSPP 483
Cdd:PHA03247  2695 LTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGpatpggpARPARPPTTAGPPAPAPPAA 2774

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  484 PTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP--- 560
Cdd:PHA03247  2775 PAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPlgg 2854

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  561 ---PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRkgSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSS 637
Cdd:PHA03247  2855 svaPGGDVRRRPPSRSPAAKPAAPARPPVRRLAR--PAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP 2932

                          330       340
                   ....*....|....*....|...
gi 1488192453  638 PQRRQSPSPSTRPIRRVSRTPEP 660
Cdd:PHA03247  2933 PPPPPRPQPPLAPTTDPAGAGEP 2955
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 536-670 5.35e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.17  E-value: 5.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  536 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 615
Cdd:PHA03307   275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192453  616 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 670
Cdd:PHA03307   351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 533-659 3.83e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 47.40  E-value: 3.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 533 RYSPSPPPKRRTASPPPPPKRRASPSPPPKR---RVSHSPPPKQRSSPVTkrrSPSLSSKHRKGSSPSRSTREARSPQPN 609
Cdd:PRK14951  367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAaaaPAPAAAPAAAASAPAA---PPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1488192453 610 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 659
Cdd:PRK14951  444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEE 493
PHA03247 PHA03247
large tegument protein UL36; Provisional
 521-715 7.71e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 7.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  521 PSPRRYSPPIQ------------RRYSPSPPPK----RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 584
Cdd:PHA03247  2562 AAPDRSVPPPRpaprpsepavtsRARRPDAPPQsarpRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPH 2641

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  585 SLSS-----KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 659
Cdd:PHA03247  2642 PPPTvpppeRPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPL 2721

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192453  660 PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPspvqsQSPSTNWSPAVP 715
Cdd:PHA03247  2722 PPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP-----PTTAGPPAPAPP 2772
PWI smart00311
PWI, domain in splicing factors;
1-32 2.24e-04

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 40.41  E-value: 2.24e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1488192453    1 MMQINLTGFLNgknAREFMGELWPLLLSAQEN 32
Cdd:smart00311  46 LLQINLTGFED---AEEFVDKLWRLLIFELKN 74
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 535-660 3.75e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 3.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 535 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 614
Cdd:PRK07764  620 APAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPA 699

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1488192453 615 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 660
Cdd:PRK07764  700 QPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEP 745
PI3K_1B_p101 pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific ...
 548-632 4.14e-04

Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IB PI3K, p110gamma, is mainly activated by seven-transmembrane G-protein-coupled receptors (GPCRs), through its regulatory subunit p101 and G-protein beta-gamma subunits.


Pssm-ID: 463109  Cd Length: 860  Bit Score: 43.90  E-value: 4.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 548 PPPPKRRASPSPPPKRRVSHSP--------PPKqrsSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 619
Cdd:pfam10486 394 SSSSPRAEKPREKSKKKSRSRLsqriyrlfKPK---SPLVLRRAKSLGNPEAKDLIPVRSKRSNSLPQQVLLRSLEPPPL 470

                          90
                  ....*....|...
gi 1488192453 620 APQTSSSPPPVRR 632
Cdd:pfam10486 471 PPLSALRHVCFRR 483
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 535-670 6.85e-04

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 43.18  E-value: 6.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 535 SPSPPPKRRTASPPpppkRRASPSPPPKRRVSHSPPPKQRSSPVTKRRsPSLSskhrKGSSPSRSTREARSPQPNKRHSP 614
Cdd:PHA03269   24 TNIPIPELHTSAAT----QKPDPAPAPHQAASRAPDPAVAPTSAASRK-PDLA----QAPTPAASEKFDPAPAPHQAASR 94

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1488192453 615 SPRPR-APQTSSSPPPVRRGA-SSSPQRRqsPSPSTRPIRRVSRTPEPKKIKKAASPS 670
Cdd:PHA03269   95 APDPAvAPQLAAAPKPDAAEAfTSAAQAH--EAPADAGTSAASKKPDPAAHTQHSPPP 150
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 539-671 8.29e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.14  E-value: 8.29e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 539 PPKRRTASPPPP--------PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSlsSKHRKGSSPSRSTR-----EARS 605
Cdd:PTZ00449  510 PPEGPEASGLPPkapgdkegEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPA--KEHKPSKIPTLSKKpefpkDPKH 587

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1488192453 606 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASS----SPQRRQSPS------PSTRPI--RRVSRTPEPKKIKKAASPSP 671
Cdd:PTZ00449  588 PKDPEEPKKPKRPRSAQRPTRPKSPKLPELLdipkSPKRPESPKspkrppPPQRPSspERPEGPKIIKSPKPPKSPKP 665
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
538-672 9.13e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 42.73  E-value: 9.13e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 538 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRhSPSPR 617
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQR-GPSGS 246

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1488192453 618 PRAPQTSSSPPPVRRGASSS-PQRRQSPSP--STRPIRRVSRTPEPKKIKKAASPSPQ 672
Cdd:pfam05539 247 PQHPPSTTSQDQSTTGDGQEhTQRRKTPPAtsNRRSPHSTATPPPTTKRQETGRPTPR 304
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 535-635 9.75e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 9.75e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 535 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK--QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 612
Cdd:PRK07764  409 APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGnaPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAP 488

                          90       100
                  ....*....|....*....|...
gi 1488192453 613 SPSPRPRAPQTSSSPPPVRRGAS 635
Cdd:PRK07764  489 APAAAPAAPAAPAAPAGADDAAT 511
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 533-715 1.02e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 533 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 612
Cdd:PRK07764  585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 613 SPSPRP---RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPirRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEP 689
Cdd:PRK07764  665 GGDGWPakaGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP--AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLP 742

                         170       180
                  ....*....|....*....|....*.
gi 1488192453 690 AAKKPPAPPSPVQSQSPSTNWSPAVP 715
Cdd:PRK07764  743 PEPDDPPDPAGAPAQPPPPPAPAPAA 768
Retinal pfam15449
Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. ...
 536-650 1.21e-03

Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. Mutations of the gene encoding this protein have been associated with retinal disorders such as retinitis pigmentosa and late-onset progressive retinal atrophy. The function of this family of proteins is unknown, but it is likely to be important in the development and function of the retina.


Pssm-ID: 464722 [Multi-domain]  Cd Length: 1293  Bit Score: 42.45  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  536 PSPPPKRRTASPPPPPKRrasPSPPPkrrVSHSPPPKQRSSPVTKRRSPSLSSkhrkGSSPSRSTREARSPQPNkRHSPS 615
Cdd:pfam15449 1072 LSPPTSKKRTSPPPQHKL---PSPPP---ESPPAQHKLSSPPTQRTEASSPSS----GPSPSPPTSPSQGHKET-RDSED 1140

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1488192453  616 PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 650
Cdd:pfam15449 1141 SQAATAKASGNTCSIFCPATSSLFEAKSPFSTAHP 1175
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 551-671 2.66e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.70  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453  551 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 630
Cdd:PHA03307   256 PLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSES 335

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1488192453  631 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 671
Cdd:PHA03307   336 SRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPS 376
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
536-646 3.15e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 3.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 536 PSPPPKRRTASPPPPPKRRASPSPPPKrrvSHSPPPKQRSSPvtKRRSPSL--------SSKHRKGSSPSRSTREARSPQ 607
Cdd:PRK12323  385 PAPAAAAPAAAAPAPAAPPAAPAAAPA---AAAAARAVAAAP--ARRSPAPealaaarqASARGPGGAPAPAPAPAAAPA 459

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1488192453 608 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSP 646
Cdd:PRK12323  460 AAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPP 498
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 535-639 3.27e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 3.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 535 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 614
Cdd:PRK07764  399 PSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTA 478

                          90       100
                  ....*....|....*....|....*
gi 1488192453 615 SPRPRAPQTSSSPPPVRRGASSSPQ 639
Cdd:PRK07764  479 APAPAPPAAPAPAAAPAAPAAPAAP 503
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 560-717 3.67e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.83  E-value: 3.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 560 PPKRRVSHSPPPKQ--RSSPVTKRRSPSLSSKHRKGSSPSRSTREA---RSPQPNKRHSPSP------RPRAPQTSSSPp 628
Cdd:PTZ00449  510 PPEGPEASGLPPKApgDKEGEEGEHEDSKESDEPKEGGKPGETKEGevgKKPGPAKEHKPSKiptlskKPEFPKDPKHP- 588

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 629 pvRRgaSSSPQRRQSPSPSTRPIRRVS-RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 707
Cdd:PTZ00449  589 --KD--PEEPKKPKRPRSAQRPTRPKSpKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPK 664

                         170
                  ....*....|
gi 1488192453 708 TNWSPAVPVK 717
Cdd:PTZ00449  665 PPFDPKFKEK 674
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 541-660 6.34e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.08  E-value: 6.34e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192453 541 KRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS---KHRKGSSPSRSTREARSPQPNKRHsPSPR 617
Cdd:PRK14951  365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASapaAPPAAAPPAPVAAPAAAAPAAAPA-AAPA 443

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1488192453 618 PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 660
Cdd:PRK14951  444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAA 486
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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