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Conserved domains on  [gi|1488192427|ref|NP_001353513|]
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serine/arginine repetitive matrix protein 1 isoform 5 [Homo sapiens]

Protein Classification

PWI domain-containing protein( domain architecture ID 10478549)

PWI domain-containing protein may function as a splicing factor; similar to Homo sapiens serine/arginine repetitive matrix protein 1 that is involved in numerous pre-mRNA processing events

CATH:  1.20.1390.10
Gene Ontology:  GO:0006397|GO:0003676
PubMed:  10322432|12600940
SCOP:  4000671

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.51e-12

PWI domain;


:

Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.51e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1488192427   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 521-655 7.73e-06

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 49.78  E-value: 7.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  521 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 600
Cdd:PHA03307   275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192427  601 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 655
Cdd:PHA03307   351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.51e-12

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.51e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1488192427   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 521-655 7.73e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 49.78  E-value: 7.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  521 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 600
Cdd:PHA03307   275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192427  601 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 655
Cdd:PHA03307   351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
PWI smart00311
PWI, domain in splicing factors;
1-32 2.20e-04

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 40.41  E-value: 2.20e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1488192427    1 MMQINLTGFLNgknAREFMGELWPLLLSAQEN 32
Cdd:smart00311  46 LLQINLTGFED---AEEFVDKLWRLLIFELKN 74
PI3K_1B_p101 pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific ...
 533-617 4.84e-04

Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IB PI3K, p110gamma, is mainly activated by seven-transmembrane G-protein-coupled receptors (GPCRs), through its regulatory subunit p101 and G-protein beta-gamma subunits.


Pssm-ID: 463109  Cd Length: 860  Bit Score: 43.90  E-value: 4.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 533 PPPPKRRASPSPPPKRRVSHSP--------PPKqrsSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 604
Cdd:pfam10486 394 SSSSPRAEKPREKSKKKSRSRLsqriyrlfKPK---SPLVLRRAKSLGNPEAKDLIPVRSKRSNSLPQQVLLRSLEPPPL 470

                          90
                  ....*....|...
gi 1488192427 605 APQTSSSPPPVRR 617
Cdd:pfam10486 471 PPLSALRHVCFRR 483
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.51e-12

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.51e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1488192427   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 521-655 7.73e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 49.78  E-value: 7.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  521 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 600
Cdd:PHA03307   275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192427  601 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 655
Cdd:PHA03307   351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
PHA03247 PHA03247
large tegument protein UL36; Provisional
 520-645 2.15e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 48.40  E-value: 2.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  520 SPSPPPKRRTASPPPPPKRRASPSPP------PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRkgSSPSRSTREARSPQP 593
Cdd:PHA03247  2826 GPLPPPTSAQPTAPPPPPGPPPPSLPlggsvaPGGDVRRRPPSRSPAAKPAAPARPPVRRLAR--PAVSRSTESFALPPD 2903

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1488192427  594 NKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 645
Cdd:PHA03247  2904 QPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEP 2955
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 518-644 4.56e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 47.02  E-value: 4.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 518 RYSPSPPPKRRTASPPPPPKRRASPSPPPKR---RVSHSPPPKQRSSPVTkrrSPSLSSKHRKGSSPSRSTREARSPQPN 594
Cdd:PRK14951  367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAaaaPAPAAAPAAAASAPAA---PPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1488192427 595 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 644
Cdd:PRK14951  444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEE 493
PHA03247 PHA03247
large tegument protein UL36; Provisional
 506-700 9.87e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 9.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  506 PSPRRYSPPIQ------------RRYSPSPPPK----RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 569
Cdd:PHA03247  2562 AAPDRSVPPPRpaprpsepavtsRARRPDAPPQsarpRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPH 2641

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  570 SLSS-----KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 644
Cdd:PHA03247  2642 PPPTvpppeRPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPL 2721

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192427  645 PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPspvqsQSPSTNWSPAVP 700
Cdd:PHA03247  2722 PPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP-----PTTAGPPAPAPP 2772
PWI smart00311
PWI, domain in splicing factors;
1-32 2.20e-04

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 40.41  E-value: 2.20e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1488192427    1 MMQINLTGFLNgknAREFMGELWPLLLSAQEN 32
Cdd:smart00311  46 LLQINLTGFED---AEEFVDKLWRLLIFELKN 74
PHA03247 PHA03247
large tegument protein UL36; Provisional
 520-700 2.72e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 2.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  520 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 599
Cdd:PHA03247  2753 GPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPT 2832

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  600 SPRPRAPQTSSSPPPV---------------RRGASSSPqrrqSPSPSTRPIRRVSRTPEPKKIKKAAS-PSPQSVRRVS 663
Cdd:PHA03247  2833 SAQPTAPPPPPGPPPPslplggsvapggdvrRRPPSRSP----AAKPAAPARPPVRRLARPAVSRSTESfALPPDQPERP 2908

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1488192427  664 SSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 700
Cdd:PHA03247  2909 PQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAP 2945
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 520-645 4.31e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.82  E-value: 4.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 520 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 599
Cdd:PRK07764  620 APAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPA 699

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1488192427 600 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 645
Cdd:PRK07764  700 QPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEP 745
PI3K_1B_p101 pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific ...
 533-617 4.84e-04

Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IB PI3K, p110gamma, is mainly activated by seven-transmembrane G-protein-coupled receptors (GPCRs), through its regulatory subunit p101 and G-protein beta-gamma subunits.


Pssm-ID: 463109  Cd Length: 860  Bit Score: 43.90  E-value: 4.84e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 533 PPPPKRRASPSPPPKRRVSHSP--------PPKqrsSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 604
Cdd:pfam10486 394 SSSSPRAEKPREKSKKKSRSRLsqriyrlfKPK---SPLVLRRAKSLGNPEAKDLIPVRSKRSNSLPQQVLLRSLEPPPL 470

                          90
                  ....*....|...
gi 1488192427 605 APQTSSSPPPVRR 617
Cdd:pfam10486 471 PPLSALRHVCFRR 483
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 524-655 7.42e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.24  E-value: 7.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  524 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSpqpnkrhSPSPRP 603
Cdd:PHA03307   266 PTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSS-------SESSRG 338

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1488192427  604 RA---------PQTSSSPPPVRRGasSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 655
Cdd:PHA03307   339 AAvspgpspsrSPSPSRPPPPADP--SSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGR 397
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 538-655 8.52e-04

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 42.79  E-value: 8.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 538 RRASPSPPPKRRVSHSPPPKQRSSPVTKRRsPSLSskhrKGSSPSRSTREARSPQPNKRHSPSPRPR-APQTSSSPPPVR 616
Cdd:PHA03269   38 QKPDPAPAPHQAASRAPDPAVAPTSAASRK-PDLA----QAPTPAASEKFDPAPAPHQAASRAPDPAvAPQLAAAPKPDA 112

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1488192427 617 RGA-SSSPQRRqsPSPSTRPIRRVSRTPEPKKIKKAASPS 655
Cdd:PHA03269  113 AEAfTSAAQAH--EAPADAGTSAASKKPDPAAHTQHSPPP 150
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
521-698 9.33e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.94  E-value: 9.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 521 PSPPPKRRTASPPPPPKRRASPSPPPKrrvSHSPPPKQRSSPvtKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPS 600
Cdd:PRK12323  385 PAPAAAAPAAAAPAPAAPPAAPAAAPA---AAAAARAVAAAP--ARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPA 459

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 601 PRPRAPQTSSSPPPVrrgASSSPQRRQSPSPSTRPIRRV----SRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAA 676
Cdd:PRK12323  460 AAARPAAAGPRPVAA---AAAAAPARAAPAAAPAPADDDpppwEELPPEFASPAPAQPDAAPAGWVAESIPDPATADPDD 536

                         170       180
                  ....*....|....*....|..
gi 1488192427 677 KKPPAPPSPVQSQSPSTNWSPA 698
Cdd:PRK12323  537 AFETLAPAPAAAPAPRAAAATE 558
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
523-657 9.57e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 42.34  E-value: 9.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 523 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRhSPSPR 602
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQR-GPSGS 246

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1488192427 603 PRAPQTSSSPPPVRRGASSS-PQRRQSPSP--STRPIRRVSRTPEPKKIKKAASPSPQ 657
Cdd:pfam05539 247 PQHPPSTTSQDQSTTGDGQEhTQRRKTPPAtsNRRSPHSTATPPPTTKRQETGRPTPR 304
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 518-700 1.09e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 518 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 597
Cdd:PRK07764  585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 598 SPSPRP---RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPirRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEP 674
Cdd:PRK07764  665 GGDGWPakaGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP--AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLP 742

                         170       180
                  ....*....|....*....|....*.
gi 1488192427 675 AAKKPPAPPSPVQSQSPSTNWSPAVP 700
Cdd:PRK07764  743 PEPDDPPDPAGAPAQPPPPPAPAPAA 768
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 520-620 1.18e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 1.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 520 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK--QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 597
Cdd:PRK07764  409 APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGnaPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAP 488

                          90       100
                  ....*....|....*....|...
gi 1488192427 598 SPSPRPRAPQTSSSPPPVRRGAS 620
Cdd:PRK07764  489 APAAAPAAPAAPAAPAGADDAAT 511
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 524-656 1.25e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 42.37  E-value: 1.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 524 PPKRRTASPPPP--------PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSlsSKHRKGSSPSRSTR-----EARS 590
Cdd:PTZ00449  510 PPEGPEASGLPPkapgdkegEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPA--KEHKPSKIPTLSKKpefpkDPKH 587

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1488192427 591 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASS----SPQRRQSPS------PSTRPI--RRVSRTPEPKKIKKAASPSP 656
Cdd:PTZ00449  588 PKDPEEPKKPKRPRSAQRPTRPKSPKLPELLdipkSPKRPESPKspkrppPPQRPSspERPEGPKIIKSPKPPKSPKP 665
Retinal pfam15449
Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. ...
 521-635 1.41e-03

Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. Mutations of the gene encoding this protein have been associated with retinal disorders such as retinitis pigmentosa and late-onset progressive retinal atrophy. The function of this family of proteins is unknown, but it is likely to be important in the development and function of the retina.


Pssm-ID: 464722 [Multi-domain]  Cd Length: 1293  Bit Score: 42.45  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  521 PSPPPKRRTASPPPPPKRrasPSPPPkrrVSHSPPPKQRSSPVTKRRSPSLSSkhrkGSSPSRSTREARSPQPNkRHSPS 600
Cdd:pfam15449 1072 LSPPTSKKRTSPPPQHKL---PSPPP---ESPPAQHKLSSPPTQRTEASSPSS----GPSPSPPTSPSQGHKET-RDSED 1140

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1488192427  601 PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 635
Cdd:pfam15449 1141 SQAATAKASGNTCSIFCPATSSLFEAKSPFSTAHP 1175
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
520-633 2.98e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 2.98e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 520 SPSPPPKRRTASPPPPPKRRASPSPPPKR-------RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 592
Cdd:PRK12323  455 AAAPAAAARPAAAGPRPVAAAAAAAPARAapaaapaPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDPATADP 534

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1488192427 593 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 633
Cdd:PRK12323  535 DDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 536-656 3.27e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.31  E-value: 3.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  536 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 615
Cdd:PHA03307   256 PLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSES 335

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1488192427  616 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 656
Cdd:PHA03307   336 SRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPS 376
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 520-624 3.99e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 3.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 520 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 599
Cdd:PRK07764  399 PSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTA 478

                          90       100
                  ....*....|....*....|....*
gi 1488192427 600 SPRPRAPQTSSSPPPVRRGASSSPQ 624
Cdd:PRK07764  479 APAPAPPAAPAPAAAPAAPAAPAAP 503
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 521-637 5.56e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 5.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 521 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSlSSKHRKGSSPSRSTREARSPQPNKRHSPS 600
Cdd:PRK07764  672 KAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQP-PQAAQGASAPSPAADDPVPLPPEPDDPPD 750

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 1488192427 601 PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIR 637
Cdd:PRK07764  751 PAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 545-702 5.63e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.44  E-value: 5.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 545 PPKRRVSHSPPPKQ--RSSPVTKRRSPSLSSKHRKGSSPSRSTREA---RSPQPNKRHSPSP------RPRAPQTSSSPp 613
Cdd:PTZ00449  510 PPEGPEASGLPPKApgDKEGEEGEHEDSKESDEPKEGGKPGETKEGevgKKPGPAKEHKPSKiptlskKPEFPKDPKHP- 588

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 614 pvRRgaSSSPQRRQSPSPSTRPIRRVS-RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 692
Cdd:PTZ00449  589 --KD--PEEPKKPKRPRSAQRPTRPKSpKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPK 664

                         170
                  ....*....|
gi 1488192427 693 TNWSPAVPVK 702
Cdd:PTZ00449  665 PPFDPKFKEK 674
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 526-645 7.43e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 39.70  E-value: 7.43e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427 526 KRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS---KHRKGSSPSRSTREARSPQPNKRHsPSPR 602
Cdd:PRK14951  365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASapaAPPAAAPPAPVAAPAAAAPAAAPA-AAPA 443

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1488192427 603 PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 645
Cdd:PRK14951  444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAA 486
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 520-635 9.70e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 39.77  E-value: 9.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192427  520 SPSPPPKRRTASPPPPPkrRASPSPPPKRRVSHSPPPKQRSSPvtkrrspslsskhrkGSSPSRSTREARSPQPNKRHSP 599
Cdd:PHA03307   342 SPGPSPSRSPSPSRPPP--PADPSSPRKRPRPSRAPSSPAASA---------------GRPTRRRARAAVAGRARRRDAT 404

                           90       100       110
                   ....*....|....*....|....*....|....*.
gi 1488192427  600 SPRPRApQTSSSPPPVRRGASSSPQRRQSPSPSTRP 635
Cdd:PHA03307   405 GRFPAG-RPRPSPLDAGAASGAFYARYPLLTPSGEP 439
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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