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Conserved domains on  [gi|1488192496|ref|NP_001353500|]
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serine/arginine repetitive matrix protein 1 isoform 6 [Homo sapiens]

Protein Classification

PWI domain-containing protein( domain architecture ID 10478549)

PWI domain-containing protein may function as a splicing factor; similar to Homo sapiens serine/arginine repetitive matrix protein 1 that is involved in numerous pre-mRNA processing events

CATH:  1.20.1390.10
Gene Ontology:  GO:0006397|GO:0003676
PubMed:  10322432|12600940
SCOP:  4000671

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.68e-12

PWI domain;


:

Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.68e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1488192496   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 537-671 5.36e-06

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.17  E-value: 5.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  537 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 616
Cdd:PHA03307   275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192496  617 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 671
Cdd:PHA03307   351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.68e-12

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.68e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1488192496   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 537-671 5.36e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.17  E-value: 5.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  537 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 616
Cdd:PHA03307   275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192496  617 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 671
Cdd:PHA03307   351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
PWI smart00311
PWI, domain in splicing factors;
1-32 2.25e-04

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 40.41  E-value: 2.25e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1488192496    1 MMQINLTGFLNgknAREFMGELWPLLLSAQEN 32
Cdd:smart00311  46 LLQINLTGFED---AEEFVDKLWRLLIFELKN 74
PI3K_1B_p101 pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific ...
 549-633 4.18e-04

Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IB PI3K, p110gamma, is mainly activated by seven-transmembrane G-protein-coupled receptors (GPCRs), through its regulatory subunit p101 and G-protein beta-gamma subunits.


Pssm-ID: 463109  Cd Length: 860  Bit Score: 43.90  E-value: 4.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 549 PPPPKRRASPSPPPKRRVSHSP--------PPKqrsSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 620
Cdd:pfam10486 394 SSSSPRAEKPREKSKKKSRSRLsqriyrlfKPK---SPLVLRRAKSLGNPEAKDLIPVRSKRSNSLPQQVLLRSLEPPPL 470

                          90
                  ....*....|...
gi 1488192496 621 APQTSSSPPPVRR 633
Cdd:pfam10486 471 PPLSALRHVCFRR 483
 
Name Accession Description Interval E-value
PWI pfam01480
PWI domain;
1-32 8.68e-12

PWI domain;


Pssm-ID: 460224 [Multi-domain]  Cd Length: 71  Bit Score: 60.98  E-value: 8.68e-12
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1488192496   1 MMQINLTGFLNgKNAREFMGELWPLLLSAQEN 32
Cdd:pfam01480  39 ELQIQLTGFLD-KDAAKFVKELWKLLLSAQES 69
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 537-671 5.36e-06

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 50.17  E-value: 5.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  537 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKhrkgSSPSRSTREARSPQPNKRHSPS 616
Cdd:PHA03307   275 WNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSS----TSSSSESSRGAAVSPGPSPSRS 350

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192496  617 PRP-RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 671
Cdd:PHA03307   351 PSPsRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGR 406
PHA03247 PHA03247
large tegument protein UL36; Provisional
 466-661 9.01e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.55  E-value: 9.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  466 RWQSPVTKSGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 545
Cdd:PHA03247  2756 RPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQ 2835

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  546 ASPPPPPKRRASPSPP------PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRkgSSPSRSTREARSPQPNKRHSPSPRP 619
Cdd:PHA03247  2836 PTAPPPPPGPPPPSLPlggsvaPGGDVRRRPPSRSPAAKPAAPARPPVRRLAR--PAVSRSTESFALPPDQPERPPQPQA 2913

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|..
gi 1488192496  620 RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 661
Cdd:PHA03247  2914 PPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEP 2955
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 534-660 3.84e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 47.40  E-value: 3.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 534 RYSPSPPPKRRTASPPPPPKRRASPSPPPKR---RVSHSPPPKQRSSPVTkrrSPSLSSKHRKGSSPSRSTREARSPQPN 610
Cdd:PRK14951  367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAaaaPAPAAAPAAAASAPAA---PPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1488192496 611 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 660
Cdd:PRK14951  444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEE 493
PHA03247 PHA03247
large tegument protein UL36; Provisional
 522-716 7.59e-05

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.86  E-value: 7.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  522 PSPRRYSPPIQ------------RRYSPSPPPK----RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 585
Cdd:PHA03247  2562 AAPDRSVPPPRpaprpsepavtsRARRPDAPPQsarpRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPH 2641

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  586 SLSS-----KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 660
Cdd:PHA03247  2642 PPPTvpppeRPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPL 2721

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1488192496  661 PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPspvqsQSPSTNWSPAVP 716
Cdd:PHA03247  2722 PPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARP-----PTTAGPPAPAPP 2772
PWI smart00311
PWI, domain in splicing factors;
1-32 2.25e-04

PWI, domain in splicing factors;


Pssm-ID: 214609 [Multi-domain]  Cd Length: 74  Bit Score: 40.41  E-value: 2.25e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 1488192496    1 MMQINLTGFLNgknAREFMGELWPLLLSAQEN 32
Cdd:smart00311  46 LLQINLTGFED---AEEFVDKLWRLLIFELKN 74
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 536-661 3.76e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 44.21  E-value: 3.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 536 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 615
Cdd:PRK07764  620 APAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPA 699

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1488192496 616 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 661
Cdd:PRK07764  700 QPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEP 745
PI3K_1B_p101 pfam10486
Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific ...
 549-633 4.18e-04

Phosphoinositide 3-kinase gamma adapter protein p101 subunit; Class I PI3Ks are dual-specific lipid and protein kinases involved in numerous intracellular signaling pathways. Class IB PI3K, p110gamma, is mainly activated by seven-transmembrane G-protein-coupled receptors (GPCRs), through its regulatory subunit p101 and G-protein beta-gamma subunits.


Pssm-ID: 463109  Cd Length: 860  Bit Score: 43.90  E-value: 4.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 549 PPPPKRRASPSPPPKRRVSHSP--------PPKqrsSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 620
Cdd:pfam10486 394 SSSSPRAEKPREKSKKKSRSRLsqriyrlfKPK---SPLVLRRAKSLGNPEAKDLIPVRSKRSNSLPQQVLLRSLEPPPL 470

                          90
                  ....*....|...
gi 1488192496 621 APQTSSSPPPVRR 633
Cdd:pfam10486 471 PPLSALRHVCFRR 483
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 540-671 5.33e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 44.01  E-value: 5.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  540 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSpqpnkrhSPSPRP 619
Cdd:PHA03307   266 PTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSS-------SESSRG 338

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1488192496  620 RA---------PQTSSSPPPVRRGasSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 671
Cdd:PHA03307   339 AAvspgpspsrSPSPSRPPPPADP--SSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGR 397
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 554-671 6.69e-04

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 43.18  E-value: 6.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 554 RRASPSPPPKRRVSHSPPPKQRSSPVTKRRsPSLSskhrKGSSPSRSTREARSPQPNKRHSPSPRPR-APQTSSSPPPVR 632
Cdd:PHA03269   38 QKPDPAPAPHQAASRAPDPAVAPTSAASRK-PDLA----QAPTPAASEKFDPAPAPHQAASRAPDPAvAPQLAAAPKPDA 112

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1488192496 633 RGA-SSSPQRRqsPSPSTRPIRRVSRTPEPKKIKKAASPS 671
Cdd:PHA03269  113 AEAfTSAAQAH--EAPADAGTSAASKKPDPAAHTQHSPPP 150
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 540-672 8.30e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 43.14  E-value: 8.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 540 PPKRRTASPPPP--------PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSlsSKHRKGSSPSRSTR-----EARS 606
Cdd:PTZ00449  510 PPEGPEASGLPPkapgdkegEEGEHEDSKESDEPKEGGKPGETKEGEVGKKPGPA--KEHKPSKIPTLSKKpefpkDPKH 587

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1488192496 607 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASS----SPQRRQSPS------PSTRPI--RRVSRTPEPKKIKKAASPSP 672
Cdd:PTZ00449  588 PKDPEEPKKPKRPRSAQRPTRPKSPKLPELLdipkSPKRPESPKspkrppPPQRPSspERPEGPKIIKSPKPPKSPKP 665
Pneumo_att_G pfam05539
Pneumovirinae attachment membrane glycoprotein G;
539-673 8.91e-04

Pneumovirinae attachment membrane glycoprotein G;


Pssm-ID: 114270 [Multi-domain]  Cd Length: 408  Bit Score: 42.73  E-value: 8.91e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 539 PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRhSPSPR 618
Cdd:pfam05539 168 PKTAVTTSKTTSWPTEVSHPTYPSQVTPQSQPATQGHQTATANQRLSSTEPVGTQGTTTSSNPEPQTEPPPSQR-GPSGS 246

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1488192496 619 PRAPQTSSSPPPVRRGASSS-PQRRQSPSP--STRPIRRVSRTPEPKKIKKAASPSPQ 673
Cdd:pfam05539 247 PQHPPSTTSQDQSTTGDGQEhTQRRKTPPAtsNRRSPHSTATPPPTTKRQETGRPTPR 304
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 536-636 9.76e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 9.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 536 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK--QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 613
Cdd:PRK07764  409 APAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGnaPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAP 488

                          90       100
                  ....*....|....*....|...
gi 1488192496 614 SPSPRPRAPQTSSSPPPVRRGAS 636
Cdd:PRK07764  489 APAAAPAAPAAPAAPAGADDAAT 511
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 534-716 1.02e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 534 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 613
Cdd:PRK07764  585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 614 SPSPRP---RAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPirRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEP 690
Cdd:PRK07764  665 GGDGWPakaGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP--AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLP 742

                         170       180
                  ....*....|....*....|....*.
gi 1488192496 691 AAKKPPAPPSPVQSQSPSTNWSPAVP 716
Cdd:PRK07764  743 PEPDDPPDPAGAPAQPPPPPAPAPAA 768
Retinal pfam15449
Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. ...
 537-651 1.18e-03

Retinal protein; This family of proteins is found in the photoreceptor cells of the retina. Mutations of the gene encoding this protein have been associated with retinal disorders such as retinitis pigmentosa and late-onset progressive retinal atrophy. The function of this family of proteins is unknown, but it is likely to be important in the development and function of the retina.


Pssm-ID: 464722 [Multi-domain]  Cd Length: 1293  Bit Score: 42.84  E-value: 1.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  537 PSPPPKRRTASPPPPPKRrasPSPPPkrrVSHSPPPKQRSSPVTKRRSPSLSSkhrkGSSPSRSTREARSPQPNkRHSPS 616
Cdd:pfam15449 1072 LSPPTSKKRTSPPPQHKL---PSPPP---ESPPAQHKLSSPPTQRTEASSPSS----GPSPSPPTSPSQGHKET-RDSED 1140

                           90       100       110
                   ....*....|....*....|....*....|....*
gi 1488192496  617 PRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 651
Cdd:pfam15449 1141 SQAATAKASGNTCSIFCPATSSLFEAKSPFSTAHP 1175
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 552-672 2.69e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 41.70  E-value: 2.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  552 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 631
Cdd:PHA03307   256 PLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSES 335

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 1488192496  632 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 672
Cdd:PHA03307   336 SRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPS 376
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
537-647 3.16e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 41.01  E-value: 3.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 537 PSPPPKRRTASPPPPPKRRASPSPPPKrrvSHSPPPKQRSSPvtKRRSPSL--------SSKHRKGSSPSRSTREARSPQ 608
Cdd:PRK12323  385 PAPAAAAPAAAAPAPAAPPAAPAAAPA---AAAAARAVAAAP--ARRSPAPealaaarqASARGPGGAPAPAPAPAAAPA 459

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1488192496 609 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSP 647
Cdd:PRK12323  460 AAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPP 498
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 536-640 3.27e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 3.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 536 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP 615
Cdd:PRK07764  399 PSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTA 478

                          90       100
                  ....*....|....*....|....*
gi 1488192496 616 SPRPRAPQTSSSPPPVRRGASSSPQ 640
Cdd:PRK07764  479 APAPAPPAAPAPAAAPAAPAAPAAP 503
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 561-718 3.71e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.83  E-value: 3.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 561 PPKRRVSHSPPPKQ--RSSPVTKRRSPSLSSKHRKGSSPSRSTREA---RSPQPNKRHSPSP------RPRAPQTSSSPp 629
Cdd:PTZ00449  510 PPEGPEASGLPPKApgDKEGEEGEHEDSKESDEPKEGGKPGETKEGevgKKPGPAKEHKPSKiptlskKPEFPKDPKHP- 588

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 630 pvRRgaSSSPQRRQSPSPSTRPIRRVS-RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 708
Cdd:PTZ00449  589 --KD--PEEPKKPKRPRSAQRPTRPKSpKLPELLDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKPPKSPK 664

                         170
                  ....*....|
gi 1488192496 709 TNWSPAVPVK 718
Cdd:PTZ00449  665 PPFDPKFKEK 674
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 542-661 6.35e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.08  E-value: 6.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496 542 KRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS---KHRKGSSPSRSTREARSPQPNKRHsPSPR 618
Cdd:PRK14951  365 KPAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASapaAPPAAAPPAPVAAPAAAAPAAAPA-AAPA 443

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 1488192496 619 PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 661
Cdd:PRK14951  444 AVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAA 486
PHA03247 PHA03247
large tegument protein UL36; Provisional
 534-715 6.92e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 6.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  534 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN--- 610
Cdd:PHA03247  2773 AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlpl 2852

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1488192496  611 ----------KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSS 680
Cdd:PHA03247  2853 ggsvapggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPP 2932

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1488192496  681 SRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAV 715
Cdd:PHA03247  2933 PPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAL 2967
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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