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Conserved domains on  [gi|1475928894|ref|NP_001352648|]
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DISP complex protein LRCH3 isoform 7 [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
80-286 3.00e-45

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 164.72  E-value: 3.00e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  80 DLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLIAS 158
Cdd:COG4886   111 NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTnLKELDLS 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 159 NNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPeELAELP-LIRLDFSCNKITTIPVCY 237
Cdd:COG4886   191 NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTnLEELDLSNNQLTDLPPLA 269

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1475928894 238 rNLRHLQTITLDNNPLQSPPAQICIKGKVHIFKYLNIQACKIAPDLPDY 286
Cdd:COG4886   270 -NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
80-286 3.00e-45

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 164.72  E-value: 3.00e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  80 DLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLIAS 158
Cdd:COG4886   111 NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTnLKELDLS 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 159 NNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPeELAELP-LIRLDFSCNKITTIPVCY 237
Cdd:COG4886   191 NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTnLEELDLSNNQLTDLPPLA 269

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1475928894 238 rNLRHLQTITLDNNPLQSPPAQICIKGKVHIFKYLNIQACKIAPDLPDY 286
Cdd:COG4886   270 -NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
81-259 4.02e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 75.50  E-value: 4.02e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  81 LTDTTR-ADLSRNRLSEIPIeacHFVS-LENLNLYQNCIRYIPEAILnlQALTFLNISRNQLSTLPVHL----------- 147
Cdd:PRK15370  239 LPDTIQeMELSINRITELPE---RLPSaLQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLpsgithlnvqs 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 148 -------CNLP--LKVLIASNNKLVSLPEEIGhlRHLMELDVSCNEIQTIPSQIGnlEALRDLNVRRNHLVHLPEELAEl 218
Cdd:PRK15370  314 nsltalpETLPpgLKTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPENLPA- 388

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1475928894 219 PLIRLDFSCNKITTIPvcyRNLRHLQT-------ITLDNNPLQSPPAQ 259
Cdd:PRK15370  389 ALQIMQASRNNLVRLP---ESLPHFRGegpqptrIIVEYNPFSERTIQ 433
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-212 2.01e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 66.73  E-value: 2.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  89 LSRNRLSEI-PIEAChfVSLENLNLYQNCIRYIpEAILNLQALTFLNISRNQLStLPVHLCNLP---------LKVLIAS 158
Cdd:cd21340    53 LQNNQIEKIeNLENL--VNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLP-PGEKLTFDPrslaalsnsLRVLNIS 128

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1475928894 159 NNKLVSLpEEIGHLRHLMELDVSCNEIQTIPSQ---IGNLEALRDLNVRRNHLVHLP 212
Cdd:cd21340   129 GNNIDSL-EPLAPLRNLEQLDASNNQISDLEELldlLSSWPSLRELDLTGNPVCKKP 184
LRR_8 pfam13855
Leucine rich repeat;
152-208 2.71e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 47.52  E-value: 2.71e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1475928894 152 LKVLIASNNKLVSLPEEI-GHLRHLMELDVSCNEIQTI-PSQIGNLEALRDLNVRRNHL 208
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
80-286 3.00e-45

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 164.72  E-value: 3.00e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  80 DLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLIAS 158
Cdd:COG4886   111 NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTnLKELDLS 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 159 NNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPeELAELP-LIRLDFSCNKITTIPVCY 237
Cdd:COG4886   191 NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTnLEELDLSNNQLTDLPPLA 269

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1475928894 238 rNLRHLQTITLDNNPLQSPPAQICIKGKVHIFKYLNIQACKIAPDLPDY 286
Cdd:COG4886   270 -NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
107-285 8.69e-28

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 115.80  E-value: 8.69e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 107 LENLNLYQNCIRYIPEAILNLQALTFLNISRNQlstlpvHLCNLP-LKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEI 185
Cdd:COG4886    75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTnLESLDLSGNQLTDLPEELANLTNLKELDLSNNQL 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 186 QTIPSQIGNLEALRDLNVRRNHLVHLPEELAELP-LIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQIcikG 264
Cdd:COG4886   149 TDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTnLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPL---A 225

                         170       180
                  ....*....|....*....|.
gi 1475928894 265 KVHIFKYLNIQACKIApDLPD 285
Cdd:COG4886   226 NLTNLETLDLSNNQLT-DLPE 245
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
78-285 3.58e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 93.07  E-value: 3.58e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  78 NHDLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLI 156
Cdd:COG4886    23 TLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTnLTELD 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 157 ASNNklvslpEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELP-LIRLDFSCNKITTIPV 235
Cdd:COG4886   103 LSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTnLKSLDLSNNQLTDLPE 176

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 1475928894 236 CYRNLRHLQTITLDNNPLQSPPAQIcikGKVHIFKYLNIQACKIApDLPD 285
Cdd:COG4886   177 ELGNLTNLKELDLSNNQITDLPEPL---GNLTNLEELDLSGNQLT-DLPE 222
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
81-259 4.02e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 75.50  E-value: 4.02e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  81 LTDTTR-ADLSRNRLSEIPIeacHFVS-LENLNLYQNCIRYIPEAILnlQALTFLNISRNQLSTLPVHL----------- 147
Cdd:PRK15370  239 LPDTIQeMELSINRITELPE---RLPSaLQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLpsgithlnvqs 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 148 -------CNLP--LKVLIASNNKLVSLPEEIGhlRHLMELDVSCNEIQTIPSQIGnlEALRDLNVRRNHLVHLPEELAEl 218
Cdd:PRK15370  314 nsltalpETLPpgLKTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPENLPA- 388

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1475928894 219 PLIRLDFSCNKITTIPvcyRNLRHLQT-------ITLDNNPLQSPPAQ 259
Cdd:PRK15370  389 ALQIMQASRNNLVRLP---ESLPHFRGegpqptrIIVEYNPFSERTIQ 433
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-212 2.01e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 66.73  E-value: 2.01e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  89 LSRNRLSEI-PIEAChfVSLENLNLYQNCIRYIpEAILNLQALTFLNISRNQLStLPVHLCNLP---------LKVLIAS 158
Cdd:cd21340    53 LQNNQIEKIeNLENL--VNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLP-PGEKLTFDPrslaalsnsLRVLNIS 128

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1475928894 159 NNKLVSLpEEIGHLRHLMELDVSCNEIQTIPSQ---IGNLEALRDLNVRRNHLVHLP 212
Cdd:cd21340   129 GNNIDSL-EPLAPLRNLEQLDASNNQISDLEELldlLSSWPSLRELDLTGNPVCKKP 184
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-257 3.61e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.96  E-value: 3.61e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  89 LSRNRLSEIP-IEACHfvSLENLNLYQNCIRYIpEAILNLQALTFLNISRNQLSTLPvHLCNLP-LKVLIASNNKLVSLp 166
Cdd:cd21340     9 LNDKNITKIDnLSLCK--NLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIE-NLENLVnLKKLYLGGNRISVV- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 167 EEIGHLRHLMELDVSCneiQTIP----------SQIGNLEALRDLNVRRNHLVHLpEELAELP-LIRLDFSCNKITTI-P 234
Cdd:cd21340    84 EGLENLTNLEELHIEN---QRLPpgekltfdprSLAALSNSLRVLNISGNNIDSL-EPLAPLRnLEQLDASNNQISDLeE 159

                         170       180
                  ....*....|....*....|....*
gi 1475928894 235 VC--YRNLRHLQTITLDNNPLQSPP 257
Cdd:cd21340   160 LLdlLSSWPSLRELDLTGNPVCKKP 184
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 88-253 7.69e-12

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 68.34  E-value: 7.69e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  88 DLSRNRLS-EIPIEACHFVSLENLNLYQNCIR-YIPEAILNLQALTFLNISRNQLS-TLPVHLCNL-PLK-VLIASNNKL 162
Cdd:PLN00113  146 DLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMkSLKwIYLGYNNLS 225

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 163 VSLPEEIGHLRHLMELD-VSCNEIQTIPSQIGNLEALRDLNVRRNHLV-HLPEELAELP-LIRLDFSCNKIT-TIPVCYR 238
Cdd:PLN00113  226 GEIPYEIGGLTSLNHLDlVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQkLISLDLSDNSLSgEIPELVI 305

                         170
                  ....*....|....*
gi 1475928894 239 NLRHLQTITLDNNPL 253
Cdd:PLN00113  306 QLQNLEILHLFSNNF 320
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
119-260 5.55e-10

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 62.02  E-value: 5.55e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 119 YIPEAIlnlqalTFLNISRNQLSTLPVHLcNLPLKVLIASNNKLVSLPEEIGHLRHLMELD------------------- 179
Cdd:PRK15370  196 CIPEQI------TTLILDNNELKSLPENL-QGNIKTLYANSNQLTSIPATLPDTIQEMELSinritelperlpsalqsld 268

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 180 VSCNEIQTIPSQIGnlEALRDLNVRRNHLVHLPEELAElPLIRLDFSCNKITTIPVCYRnlRHLQTITLDNNPLQSPPAQ 259
Cdd:PRK15370  269 LFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLPS-GITHLNVQSNSLTALPETLP--PGLKTLEAGENALTSLPAS 343


                  .
gi 1475928894 260 I 260
Cdd:PRK15370  344 L 344
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
61-252 1.26e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 60.33  E-value: 1.26e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  61 VLSLSGRKLREFPRGAANhdLTDTTRADLSRNRLSEIPiEACHFVSLENLNLYQNCIRYIPEaILNLQALTFLNISRNQL 140
Cdd:COG4886   209 ELDLSGNQLTDLPEPLAN--LTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQL 284

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 141 STLPV-HLCNLPLKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELP 219
Cdd:COG4886   285 TDLKLkELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364

                         170       180       190
                  ....*....|....*....|....*....|...
gi 1475928894 220 LIRLDFSCNKITTIPVCYRNLRHLQTITLDNNP 252
Cdd:COG4886   365 LLLTLGLLGLLEATLLTLALLLLTLLLLLLTTT 397
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 81-231 2.49e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 60.25  E-value: 2.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  81 LTDTTRADLSRNRLS-EIPIEACHFVSLENLNLYQNCIR-YIPEAILNLQALTFLNISRNQLS----------------- 141
Cdd:PLN00113  235 LTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgeipelviqlqnleilh 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 142 --------TLPVHLCNLP-LKVLIASNNKLV-SLPEEIGHLRHLMELDVSCNEIQ------------------------- 186
Cdd:PLN00113  315 lfsnnftgKIPVALTSLPrLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLTgeipeglcssgnlfklilfsnsleg 394

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1475928894 187 TIPSQIGNLEALRDLNVRRNHLV-HLPEELAELPLIR-LDFSCNKIT 231
Cdd:PLN00113  395 EIPKSLGACRSLRRVRLQDNSFSgELPSEFTKLPLVYfLDISNNNLQ 441
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 80-208 1.33e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 57.94  E-value: 1.33e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  80 DLTDTTRADLSRNRLS-EIPiEACHFVSLENLNLYQNCIR-YIPEAILNLQALTFLNISRNQLS-TLPVHLCNLP-LKVL 155
Cdd:PLN00113  450 DMPSLQMLSLARNKFFgGLP-DSFGSKRLENLDLSRNQFSgAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKkLVSL 528

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1475928894 156 IASNNKLV-SLPEEIGHLRHLMELDVSCNEIQ-TIPSQIGNLEALRDLNVRRNHL 208
Cdd:PLN00113  529 DLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
107-285 1.28e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 54.17  E-value: 1.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 107 LENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLPLKVLIASNNKLVSLPEEIGHLRHLMELDV-----S 181
Cdd:COG4886     2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLllsllL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 182 CNEIQTIPSQIGNLEALRDLNVRRNhlvhlpEELAELP-LIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQI 260
Cdd:COG4886    82 LSLLLLGLTDLGDLTNLTELDLSGN------EELSNLTnLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPL 155

                         170       180
                  ....*....|....*....|....*
gi 1475928894 261 cikGKVHIFKYLNIQACKIApDLPD 285
Cdd:COG4886   156 ---GNLTNLKSLDLSNNQLT-DLPE 176
LRR_8 pfam13855
Leucine rich repeat;
152-208 2.71e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 47.52  E-value: 2.71e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1475928894 152 LKVLIASNNKLVSLPEEI-GHLRHLMELDVSCNEIQTI-PSQIGNLEALRDLNVRRNHL 208
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
81-247 1.58e-06

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 50.93  E-value: 1.58e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894  81 LTDTTRADLSRNRLSEIPIEAChfvsleNLNLYQNCIRYIPEAILNLQALTflnISRNQLSTLPV-------------HL 147
Cdd:PRK15387  304 LQELSVSDNQLASLPALPSELC------KLWAYNNQLTSLPTLPSGLQELS---VSDNQLASLPTlpselyklwaynnRL 374

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 148 CNLP-----LKVLIASNNKLVSLPEEIGHLRHLMeldVSCNEIQTIPSQIgnlEALRDLNVRRNHLVHLPEELAELplir 222
Cdd:PRK15387  375 TSLPalpsgLKELIVSGNRLTSLPVLPSELKELM---VSGNRLTSLPMLP---SGLLSLSVYRNQLTRLPESLIHL---- 444

                         170       180       190
                  ....*....|....*....|....*....|
gi 1475928894 223 ldfscNKITTI-----PVCYRNLRHLQTIT 247
Cdd:PRK15387  445 -----SSETTVnlegnPLSERTLQALREIT 469
LRR_8 pfam13855
Leucine rich repeat;
173-253 3.18e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 44.44  E-value: 3.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 173 RHLMELDVSCNEIQTIPSqignlEALRDLNvrrnhlvhlpeelaelPLIRLDFSCNKITTI-PVCYRNLRHLQTITLDNN 251
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDD-----GAFKGLS----------------NLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGN 59


                  ..
gi 1475928894 252 PL 253
Cdd:pfam13855  60 RL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 120-260 9.26e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.14  E-value: 9.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 120 IPEAILNLQALTFLNISRNQLS-TLPVHLCNL--PLKVLIASNNKLV-SLPEeiGHLRHLMELDVSCNEIQ-TIPSQIGN 194
Cdd:PLN00113   85 ISSAIFRLPYIQTINLSNNQLSgPIPDDIFTTssSLRYLNLSNNNFTgSIPR--GSIPNLETLDLSNNMLSgEIPNDIGS 162

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 195 LEALRDLNVRRNHLV-HLPEELAELPLIR-LDFSCNKIT-TIPVCYRNLRHLQTITLDNNPLQSP-PAQI 260
Cdd:PLN00113  163 FSSLKVLDLGGNVLVgKIPNSLTNLTSLEfLTLASNQLVgQIPRELGQMKSLKWIYLGYNNLSGEiPYEI 232
LRR_8 pfam13855
Leucine rich repeat;
106-162 1.28e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 37.12  E-value: 1.28e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 106 SLENLNLYQNCIRYI-PEAILNLQALTFLNISRNQLSTL-PVHLCNLP-LKVLIASNNKL 162
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPsLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 102-225 4.28e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 39.80  E-value: 4.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1475928894 102 CHFVS------LENLNLYQNCIR-YIPEAILNLQALTFLNISRNQLSTlpvhlcnlplkvliasnnklvSLPEEIGHLRH 174
Cdd:PLN03150  409 CQFDStkgkwfIDGLGLDNQGLRgFIPNDISKLRHLQSINLSGNSIRG---------------------NIPPSLGSITS 467

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1475928894 175 LMELDVSCNEIQ-TIPSQIGNLEALRDLNVRRNHLV-HLPEELAELPLIRLDF 225
Cdd:PLN03150  468 LEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSgRVPAALGGRLLHRASF 520
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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