|
Name |
Accession |
Description |
Interval |
E-value |
| HkD_Girdin |
cd22229 |
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation ... |
10-165 |
3.78e-90 |
|
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration.
Pssm-ID: 411800 Cd Length: 156 Bit Score: 289.38 E-value: 3.78e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 10 LEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFY 89
Cdd:cd22229 1 LEQFMSSPLVTWVKTFGPLATGNGTPLDEYVALVDGVFLNEVMLQINPKSSNQRVNKKVNNDASLRIQNLSILVKQIKLY 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1465187875 90 YQETLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22229 81 YQETLQQLIMMSLPNVLVLGRNPLSEQGTEEMKKLLLLLLGCAVQCERKEEFIERIQTLDFDTKAAVAAHIQEVTH 156
|
|
| HkD_Daple |
cd22228 |
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) ... |
13-165 |
1.34e-62 |
|
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) and similar proteins; Protein Daple, also called coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling.
Pssm-ID: 411799 Cd Length: 153 Bit Score: 210.55 E-value: 1.34e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 13 FMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFYYQE 92
Cdd:cd22228 1 FLQSPLVTWVKTFGPLGFGSEDKLSMYMDLVDGVFLNKIMLQIDPRPTNQRVNKHVNNDVNLRIQNLTILVRHIKTYYQE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1465187875 93 TLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22228 81 VLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKMLLLVLGCAVQCERKEEFIERIKQLDIETQAAIVSHIQEVTH 153
|
|
| HkD_HkRP |
cd22223 |
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, ... |
13-165 |
2.72e-60 |
|
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration. Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing. All family members contain a conserved globular Hook domain which folds as a variant of the helical calponin homology (CH) domain.
Pssm-ID: 411794 Cd Length: 149 Bit Score: 203.59 E-value: 2.72e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 13 FMTSPLVTWVKTFgplaAGNGTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFYYQE 92
Cdd:cd22223 1 FLSSPLVTWAKTF----ADDGSAELSYTDLVDGVFLNNVMLQIDPRPFSEVSNRNVDDDVNARIQNLDLLLRNIKSFYQE 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1465187875 93 TLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22223 77 VLQQLIVMKLPDILTIGREPESEQSLEELEKLLLLLLGCAVQCERKEEFIERIKNLDLEVQHALVACIQEVTD 149
|
|
| HkD_Gipie |
cd22230 |
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar ... |
11-164 |
3.78e-36 |
|
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar proteins; Gipie, also called coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing.
Pssm-ID: 411801 Cd Length: 170 Bit Score: 135.34 E-value: 3.78e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 11 EQFMTSPLVTWVKTF------------GPLAAGNGTNLD---EYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLR 75
Cdd:cd22230 1 EEFMSGALVTWALGFeglvgeeedslgFPEEEEEEGTLDaekRFLRLSNGDLLNRVMGIIDPSPRGGPRMRGDDGPAAHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 76 MHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAA 155
Cdd:cd22230 81 VQNLHILWGRLRDFYQEELQQLILSPPPDLQVMGRDPFTEEAVQELEKLLRLLLGAAVQCERRELFIRHIQGLDLDVQAE 160
|
....*....
gi 1465187875 156 VAAHIQEVT 164
Cdd:cd22230 161 LAEAIQEVT 169
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
596-1373 |
3.99e-25 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 114.38 E-value: 3.99e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAE---ELENELHHLEKEneLLQKKITNLKitcEKIEALEQENSELEREN 672
Cdd:TIGR02168 181 LERTRENLDRLEDILNELERQLKSLERQAEKAErykELKAELRELELA--LLVLRLEELR---EELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 673 RKLKKTLdsfKNLTFQLESLEKENSQLDEENLELRRNVESLKCA-SMKMAQLQLENKELESEKEQLKKGLELLKASFKKT 751
Cdd:TIGR02168 256 EELTAEL---QELEEKLEELRLEVSELEEEIEELQKELYALANEiSRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 752 ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:TIGR02168 333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 832 KQLEKENKRLRQQAEIKDTTLEENNVKigNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDL 911
Cdd:TIGR02168 410 ERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 912 VSEKLKTQQMNNDLEKLTHELEKIGLNKERLlhdeqstddsryklleSKLESTLKKSLEIKEEKIAALEARLEESTNYnq 991
Cdd:TIGR02168 488 QARLDSLERLQENLEGFSEGVKALLKNQSGL----------------SGILGVLSELISVDEGYEAAIEAALGGRLQA-- 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 992 QLRQELKTVKKNYEALKQRQDEERMV--------QSSPPISGEDNKWERESQETTRELLKVKDRL--------------- 1048
Cdd:TIGR02168 550 VVVENLNAAKKAIAFLKQNELGRVTFlpldsikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggvlvvd 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1049 -------------------------------------------IEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILA 1085
Cdd:TIGR02168 630 dldnalelakklrpgyrivtldgdlvrpggvitggsaktnssiLERRREIEELEEKIEELEEKIAELEKALAELRKELEE 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1086 LQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1165
Cdd:TIGR02168 710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1166 LHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKG----QLEDLEKMLKVEQEKMLLENKNHETVAAEYK 1241
Cdd:TIGR02168 790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAaterRLEDLEEQIEELSEDIESLAAEIEELEELIE 869
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1242 KLcgeNDRLNHtysqLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDitstklnnqcELLSQLKGNLE 1321
Cdd:TIGR02168 870 EL---ESELEA----LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELR----------EKLAQLELRLE 932
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 1322 EENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKL 1373
Cdd:TIGR02168 933 GLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
258-1079 |
1.09e-22 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 106.29 E-value: 1.09e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 258 AKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALRE--KAVRVDKLESEVSRYKER 335
Cdd:TIGR02168 165 AGISKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAELREleLALLVLRLEELREELEEL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 336 LHDIEFYKARVEELKEDNQVLLETKTMLEDQLegtRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTL 415
Cdd:TIGR02168 245 QEELKEAEEELEELTAELQELEEKLEELRLEV---SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 416 EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLgheVNELTSSRLLKLEMENQS--LTKTVEELRTTVDSVEG----N 489
Cdd:TIGR02168 322 EAQLEELESKLDELAEELAELEEKLEELKEELESL---EAELEELEAELEELESRLeeLEEQLETLRSKVAQLELqiasL 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 490 ASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQ--NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTV 567
Cdd:TIGR02168 399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAElkELQAELEELEEELEELQEELERLEEALEELREELEEAEQALD 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 568 SSLRQRSQISAEARV-KDIEKENKILHESIKETSSKLSKIEFEKRQIKkELEHYKEKGERAEE--LENELHHLEKENELL 644
Cdd:TIGR02168 479 AAERELAQLQARLDSlERLQENLEGFSEGVKALLKNQSGLSGILGVLS-ELISVDEGYEAAIEaaLGGRLQAVVVENLNA 557
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 645 QKKItnlkitcekIEALEQENS--------------ELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNV 710
Cdd:TIGR02168 558 AKKA---------IAFLKQNELgrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVV 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 711 ESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASfkktERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLE 790
Cdd:TIGR02168 629 DDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGS----AKTNSSILERRREIEELEEKIEELEEKIAELEKALAELR 704
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 791 MENQTLQKNLEELKI----SSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN 866
Cdd:TIGR02168 705 KELEELEEELEQLRKeleeLSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEI 784
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 867 KTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDE 946
Cdd:TIGR02168 785 EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 947 QstddsrykLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQdeERMVQSSPPISGE 1026
Cdd:TIGR02168 865 E--------ELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELR--EKLAQLELRLEGL 934
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|...
gi 1465187875 1027 DNKwERESQETTREllKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL 1079
Cdd:TIGR02168 935 EVR-IDNLQERLSE--EYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
462-1300 |
5.49e-22 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 103.98 E-value: 5.49e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 462 LLKLEMENQSLTK---TVEELRTTVDSVEGNASKILK-MEKENQRLSKKVEILENEIVQEKQSLQNcqnlSKDLMKEKAQ 537
Cdd:TIGR02168 178 ERKLERTRENLDRledILNELERQLKSLERQAEKAERyKELKAELRELELALLVLRLEELREELEE----LQEELKEAEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 538 LEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKEL 617
Cdd:TIGR02168 254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY-ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 618 EHYKEkgeRAEELENELHHLEKENELLQKKITNLKITCEKIEALEQE-NSELERENRKLKKTLDSFKNLTFQLESLEKEN 696
Cdd:TIGR02168 333 DELAE---ELAELEEKLEELKEELESLEAELEELEAELEELESRLEElEEQLETLRSKVAQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 697 SQLDEENLELRRNVESLKcasmkMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN 776
Cdd:TIGR02168 410 ERLEDRRERLQQEIEELL-----KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRL--------EQLEKENK---SLE---QETSQ--LEKDKKQLEKENKR 840
Cdd:TIGR02168 485 AQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvlsELISVDEGyeaAIEaalGGRLQavVVENLNAAKKAIAF 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 841 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKEnkelVKRATIDIKTLVTLREDLvseklktQQ 920
Cdd:TIGR02168 565 LKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK----LRKALSYLLGGVLVVDDL-------DN 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 921 MNNDLEKLTHELEKIGLNKERLLHDEQST---DDSRYKLLESKLE-STLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 996
Cdd:TIGR02168 634 ALELAKKLRPGYRIVTLDGDLVRPGGVITggsAKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEE 713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 997 LKTVKKNYEALKQ------------RQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQA 1064
Cdd:TIGR02168 714 LEQLRKELEELSRqisalrkdlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1065 LKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQStslmnqnaqlliqqSSLENENESVIK 1144
Cdd:TIGR02168 794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI--------------EELSEDIESLAA 859
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1145 EREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEdlekmLKVEQE 1224
Cdd:TIGR02168 860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE-----LRLEGL 934
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 1225 KMLLENKNhETVAAEYKKLCGENDRLnhtYSQLLKETEVLQTDHKNLKSLLNNskLEQTRLEA--EFSKLKEQYQQLD 1300
Cdd:TIGR02168 935 EVRIDNLQ-ERLSEEYSLTLEEAEAL---ENKIEDDEEEARRRLKRLENKIKE--LGPVNLAAieEYEELKERYDFLT 1006
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
249-1080 |
1.10e-21 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 103.21 E-value: 1.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 249 LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnLLSDARSARMYRDELDALREKavrVDKLESE 328
Cdd:TIGR02168 230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLE---VSELEEEIEELQKELYALANE---ISRLEQQ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 329 VSRYKERLH----DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDM 400
Cdd:TIGR02168 304 KQILRERLAnlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEEleslEAELEELEAELEELESRLEELEEQLET 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 401 DRKKIEELmEENMTLEMAQKQSMDEslhlgwELEQISRTSELSEAPQKSLGhevNELTSSRLLKLEMENQSLTKTVEELR 480
Cdd:TIGR02168 384 LRSKVAQL-ELQIASLNNEIERLEA------RLERLEDRRERLQQEIEELL---KKLEEAELKELQAELEELEEELEELQ 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 481 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQEN 560
Cdd:TIGR02168 454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 561 EHLNQTVSSLRQRSQ----ISAEARVKDIE--KENKILHESIKE-TSSKLSKIEFEKRQIKKELEHYKEKGERAEELENE 633
Cdd:TIGR02168 534 GYEAAIEAALGGRLQavvvENLNAAKKAIAflKQNELGRVTFLPlDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 634 LHhlekenELLQKKITNLKITCEKIEALEQENsELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESL 713
Cdd:TIGR02168 614 LR------KALSYLLGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKI 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKasfKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEmen 793
Cdd:TIGR02168 687 EELEEKIAELEKALAELRKELEELEEELEQLR---KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE--- 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 794 qtlqknlEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Cdd:TIGR02168 761 -------AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEklktqqmnndLEKLTHELEKIGLNKERLLHDEQSTDDSR 953
Cdd:TIGR02168 834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE----------LEALLNERASLEEALALLRSELEELSEEL 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 954 YKLLESKLEstLKKSLEIKEEKIAALEARLEESTNYNQQLRQELktvkknyeALKQRQDEERMVQSSPPISGEDNKWERE 1033
Cdd:TIGR02168 904 RELESKRSE--LRRELEELREKLAQLELRLEGLEVRIDNLQERL--------SEEYSLTLEEAEALENKIEDDEEEARRR 973
|
810 820 830 840
....*....|....*....|....*....|....*....|....*..
gi 1465187875 1034 SQETTRELlkvkDRLIEVernNATLQAEKQALKTQLKQLETQNNNLQ 1080
Cdd:TIGR02168 974 LKRLENKI----KELGPV---NLAAIEEYEELKERYDFLTAQKEDLT 1013
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
517-1205 |
6.25e-21 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 100.09 E-value: 6.25e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 517 EKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEaRVKDIEKENKILHESI 596
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKD-KINKLNSDLSKINSEI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 597 KETSSKLSKIEFEKRQIKKELEHYKEKgerAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLK 676
Cdd:TIGR04523 113 KNDKEQKNKLEVELNKLEKQKKENKKN---IDKFLTEIKKKEKELEKLNNKYNDLK---KQKEELENELNLLEKEKLNIQ 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 677 KTLDSFKN-------LTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLKKGLELLKASFK 749
Cdd:TIGR04523 187 KNIDKIKNkllklelLLSNLKKKIQKNKSLESQISELKKQNNQLK------DNIEKKQQEINEKTTEISNTQTQLNQLKD 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEME-NQTLQKNL-EELKISSKRLEQLEKENKSLEQETSQL 827
Cdd:TIGR04523 261 EQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQkEQDWNKELkSELKNQEKKLEEIQNQISQNNKIISQL 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 828 EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:TIGR04523 341 NEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 908 REDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLE--SKLESTLKKSLEIKEEKIAALEARLEE 985
Cdd:TIGR04523 421 KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKvlSRSINKIKQNLEQKQKELKSKEKELKK 500
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 986 STNYNQQLRQELKTVKKNYEALKQRQD--EERMVQSSPPISGEDNKWERESQETTRELLK-----VKDRLIEVERNNATL 1058
Cdd:TIGR04523 501 LNEEKKELEEKVKDLTKKISSLKEKIEklESEKKEKESKISDLEDELNKDDFELKKENLEkeideKNKEIEELKQTQKSL 580
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1059 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1138
Cdd:TIGR04523 581 KKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1139 NESVIKEREDLKSLYDSLI---KDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1205
Cdd:TIGR04523 661 WPEIIKKIKESKTKIDDIIelmKDWLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKKLDEFSKEL 730
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
571-1073 |
8.64e-21 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 99.75 E-value: 8.64e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 571 RQRSQISAEARVKDIEKENK-----ILHEsIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQ 645
Cdd:PRK03918 180 RLEKFIKRTENIEELIKEKEkeleeVLRE-INEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 646 KKITNLKitcEKIEALEQENSELERENRKLKK---------TLDSFKNLTFQ-LESLEKENSQLDEENLELRRNVESLKC 715
Cdd:PRK03918 259 EKIRELE---ERIEELKKEIEELEEKVKELKElkekaeeyiKLSEFYEEYLDeLREIEKRLSRLEEEINGIEERIKELEE 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 716 ASMKMAQLQLENKELESEKEQLKKGLELL---KASFKKTERLEVSYQGLDIEN-----QRLQKTLENSNKKIQQLESELQ 787
Cdd:PRK03918 336 KEERLEELKKKLKELEKRLEELEERHELYeeaKAKKEELERLKKRLTGLTPEKlekelEELEKAKEEIEEEISKITARIG 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 788 DLEMENQTLQKNLEELKIS-----------------------SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:PRK03918 416 ELKKEIKELKKAIEELKKAkgkcpvcgrelteehrkelleeyTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEL 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 845 AEIKDTT-----------------LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKratidiktlvtl 907
Cdd:PRK03918 496 IKLKELAeqlkeleeklkkynleeLEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEK------------ 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 908 redlvseklKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLEStlKKSLEIKEEKIAALEARLEEST 987
Cdd:PRK03918 564 ---------KLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDA--EKELEREEKELKKLEEELDKAF 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 988 NYNQQLRQELKTVKKNYEALKQRQDEERMVQssppISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKT 1067
Cdd:PRK03918 633 EELAETEKRLEELRKELEELEKKYSEEEYEE----LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
|
....*.
gi 1465187875 1068 QLKQLE 1073
Cdd:PRK03918 709 AKKELE 714
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
610-1224 |
9.17e-21 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 99.75 E-value: 9.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 610 KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNLTFQL 689
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEIS---SELPELREELEKLEKEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 690 ESLEKENSQLDEENLELRRNVESLKcasmkmaqlqLENKELESEKEQLKKglelLKASFKKTERLEVSYQGLDIENQRLQ 769
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELK----------KEIEELEEKVKELKE----LKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 770 KTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEK------ENKSLEQETSQLEKDKKQLEKEN-KRLR 842
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEErhelyeEAKAKKEELERLKKRLTGLTPEKlEKEL 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 843 QQAEIKDTTLEEN----NVKIGNLEKENKTLSKEIGIYKES------CVRLKElEKENKELVKRATIDIKtlvtlreDLV 912
Cdd:PRK03918 394 EELEKAKEEIEEEiskiTARIGELKKEIKELKKAIEELKKAkgkcpvCGRELT-EEHRKELLEEYTAELK-------RIE 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 913 SEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDdsRYKLLESKLESTLKKSLEIKEEKIAALEARLEEstnynqq 992
Cdd:PRK03918 466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAE--QLKELEEKLKKYNLEELEKKAEEYEKLKEKLIK------- 536
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 993 LRQELKTVKKNYEALKQRQDEERMVqssppisgednkwERESQETTRELLKVKDRLIEVERNNAtlqaekQALKTQLKQL 1072
Cdd:PRK03918 537 LKGEIKSLKKELEKLEELKKKLAEL-------------EKKLDELEEELAELLKELEELGFESV------EELEERLKEL 597
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1073 EtqnnnlqaqilALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaqlliqqSSLENENESVIKEREDLKSL 1152
Cdd:PRK03918 598 E-----------PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL-----------AETEKRLEELRKELEELEKK 655
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 1153 YDSliKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQE 1224
Cdd:PRK03918 656 YSE--EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
476-1270 |
9.61e-21 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 100.14 E-value: 9.61e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 476 VEELRTTVDSVEGNASKILKMEKENQRLSK-KVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK 554
Cdd:TIGR02169 193 IDEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 555 ILEQENEHlnqtVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEkgeRAEELENEL 634
Cdd:TIGR02169 273 LLEELNKK----IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA---EIEELEREI 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 635 HHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKnltfqlESLEKENSQLDEENLELRRNVESLK 714
Cdd:TIGR02169 346 EEERKRRDKLTEEYAELK---EELEDLRAELEEVDKEFAETRDELKDYR------EKLEKLKREINELKRELDRLQEELQ 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 715 CASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERlevsyqgldiENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Cdd:TIGR02169 417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----------KLEQLAADLSKYEQELYDLKEEYDRVEKELS 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 795 TLQKNLEELKISSKRLEQLEKENKSLEQE-----------TSQLEKDKKQL-----------------------EKENKR 840
Cdd:TIGR02169 487 KLQRELAEAEAQARASEERVRGGRAVEEVlkasiqgvhgtVAQLGSVGERYataievaagnrlnnvvveddavaKEAIEL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 841 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIykesCVRLKELEKENKELVK---------------RATIDIKTLV 905
Cdd:TIGR02169 567 LKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGF----AVDLVEFDPKYEPAFKyvfgdtlvvedieaaRRLMGKYRMV 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 906 TLREDLV---------------------SEKLKTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDSRYKLLESKLE-S 963
Cdd:TIGR02169 643 TLEGELFeksgamtggsraprggilfsrSEPAELQRLRERLEGLKRELSSL---QSELRRIENRLDELSQELSDASRKiG 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 964 TLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQR-----------QDEERMVQSSPPISGEDNKwER 1032
Cdd:TIGR02169 720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARieeleedlhklEEALNDLEARLSHSRIPEI-QA 798
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1033 ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENS 1112
Cdd:TIGR02169 799 ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1113 TLnsqstslmnqnaqlliqqsslenenesvIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLE 1192
Cdd:TIGR02169 879 DL----------------------------ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE 930
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1193 VEHRDLEDRYNQLLKQKGQLEDLEKM----LKVEQEKMLLENKN------HETVAAEYKKLCGENDRLNHTYSQLLKETE 1262
Cdd:TIGR02169 931 EELSEIEDPKGEDEEIPEEELSLEDVqaelQRVEEEIRALEPVNmlaiqeYEEVLKRLDELKEKRAKLEEERKAILERIE 1010
|
....*...
gi 1465187875 1263 VLQTDHKN 1270
Cdd:TIGR02169 1011 EYEKKKRE 1018
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
705-1378 |
1.24e-20 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 99.75 E-value: 1.24e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 705 ELRRNVESLKcasmKMAQLQLENKELESEKEQLKKGLELLKASFKKTE--RLEVSYQGLDIENQRLQKTLENSNKKIQQL 782
Cdd:TIGR02168 197 ELERQLKSLE----RQAEKAERYKELKAELRELELALLVLRLEELREEleELQEELKEAEEELEELTAELQELEEKLEEL 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 783 ESELQDLEMENQTLQKNLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:TIGR02168 273 RLEVSELEEEIEELQKELYALAN---EISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEEL 349
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 863 EKENKTLSKEigiykescvrLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERL 942
Cdd:TIGR02168 350 KEELESLEAE----------LEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL 419
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 943 LHD----EQSTDDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQ 1018
Cdd:TIGR02168 420 QQEieelLKKLEEAELKELQAELE-ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1019 SSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATlqAEKQALKTQLKQLETQNNNLQAQILALQRQ--------- 1089
Cdd:TIGR02168 499 ENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEA--AIEAALGGRLQAVVVENLNAAKKAIAFLKQnelgrvtfl 576
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1090 --------------TVSLQEQN------------------------------TTLQTQNAKL------------------ 1107
Cdd:TIGR02168 577 pldsikgteiqgndREILKNIEgflgvakdlvkfdpklrkalsyllggvlvvDDLDNALELAkklrpgyrivtldgdlvr 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1108 ----------QVENSTLNsQSTSLMNQNAQLLIQQS---SLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEY 1174
Cdd:TIGR02168 657 pggvitggsaKTNSSILE-RRREIEELEEKIEELEEkiaELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDL 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1175 ESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVE----QEKMLLENKNHETVAAEYKKLCGENDRL 1250
Cdd:TIGR02168 736 ARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEieelEAQIEQLKEELKALREALDELRAELTLL 815
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1251 NHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQ 1330
Cdd:TIGR02168 816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895
|
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 1465187875 1331 IQTLMLQNRTLLEQNMESKDLFHvEQRqyiDKLNELRRQKEKLEEKIM 1378
Cdd:TIGR02168 896 LEELSEELRELESKRSELRRELE-ELR---EKLAQLELRLEGLEVRID 939
|
|
| HkD_SF |
cd22211 |
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ... |
16-165 |
3.64e-20 |
|
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.
Pssm-ID: 411792 Cd Length: 145 Bit Score: 88.49 E-value: 3.64e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 16 SPLVTWVKTFGPLaagngTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDAS--LRMHNLSILVRQIKFYYQET 93
Cdd:cd22211 2 AALLAWINTFPLS-----SPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSSDNwvLKLNNLKKLYRSLSKYYREV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1465187875 94 LQQLIM-MSLPNVLIIGKNPfseqGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22211 77 LGQQLSdLPLPDLSAIARDG----DEEEIVKLLELVLGAAVQCENKEEYIARIQQLDESTQAELMLIIQEVLE 145
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
253-890 |
4.41e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 94.36 E-value: 4.41e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLlsdarsarmyRDELDALREKavrVDKLESEVSRY 332
Cdd:PRK03918 167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEI----------SSELPELREE---LEKLEKEVKEL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 333 KERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEnlqlkaklhdmemerdmdRKKIEELMEEN 412
Cdd:PRK03918 234 EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE------------------LKELKEKAEEY 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 413 MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLghevnELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgnasK 492
Cdd:PRK03918 296 IKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL-----EEKEERLEELKKKLKELEKRLEELEERHELYE----E 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 493 ILKMEKENQRLSKKVEILENEIVQEKQslqncqnlsKDLMKEKAQLEKTIETLREnserQIKILEQENEHLNQTVSSLRQ 572
Cdd:PRK03918 367 AKAKKEELERLKKRLTGLTPEKLEKEL---------EELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEELKK 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 573 RSQISAEARVKDIEKENKilhESIKETSSKLSKIEFEKrqikkelehyKEKGERAEELENELHHLEKENElLQKKITNLK 652
Cdd:PRK03918 434 AKGKCPVCGRELTEEHRK---ELLEEYTAELKRIEKEL----------KEIEEKERKLRKELRELEKVLK-KESELIKLK 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 653 ITCEKIEALEQENS-----ELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL--QL 725
Cdd:PRK03918 500 ELAEQLKELEEKLKkynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELlkEL 579
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 726 ENKELESEKEqLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMenqtLQKNLEEL-- 803
Cdd:PRK03918 580 EELGFESVEE-LEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE----LRKELEELek 654
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKeIGIYKESCVRL 883
Cdd:PRK03918 655 KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALER-VEELREKVKKY 733
|
....*..
gi 1465187875 884 KELEKEN 890
Cdd:PRK03918 734 KALLKER 740
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
181-814 |
4.93e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 93.98 E-value: 4.93e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 181 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHflphasssaqspcgspgmKRTESRQHLSVELADAKAKI 260
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------------------KEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsarmyRDELDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEK--------------VKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 341 fykarveelkednqvllETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEmerdmdrKKIEELMEENMTLEMAqK 420
Cdd:PRK03918 314 -----------------KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE-------KRLEELEERHELYEEA-K 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 421 QSMDESLHL-----GWELEQISRTSELSEAPQKSLGHEVNELTsSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILK 495
Cdd:PRK03918 369 AKKEELERLkkrltGLTPEKLEKELEELEKAKEEIEEEISKIT-ARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 496 MEKENQRLSKKVEIleneivqekqslqncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENE--HLNQTVSSLRQR 573
Cdd:PRK03918 448 EHRKELLEEYTAEL-------------------KRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKEL 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 574 SQISAEARVKDIEKENkilhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PRK03918 509 EEKLKKYNLEELEKKA----EEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGF 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 654 TCekIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEenlelrrnveslkcASMKMAQLQLENKELESE 733
Cdd:PRK03918 585 ES--VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDK--------------AFEELAETEKRLEELRKE 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 734 KEQLKKglellKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813
Cdd:PRK03918 649 LEELEK-----KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERV 723
|
.
gi 1465187875 814 E 814
Cdd:PRK03918 724 E 724
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-904 |
9.76e-19 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 93.59 E-value: 9.76e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARmyrdelDALREKAVRVDKLESEVSR 331
Cdd:TIGR02169 288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------REIEEERKRRDKLTEEYAE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 332 YKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR02169 362 LKEELEDLR---AELEEVDKEFAETRDELKDYREKLEKLK---REINELKRELDRLQEELQRLSEELADLNAAIAGIEAK 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRTTV-------- 483
Cdd:TIGR02169 436 INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV-EKELSKLQRELAEAEAQARASEERVrggravee 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 484 ---DSVEGNASKILKMEKENQRLSKKVEI-----LENEIVQEKQSLQNCQNLSKDL---------MKEKAQLEKTIETLR 546
Cdd:TIGR02169 515 vlkASIQGVHGTVAQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKEAIELLKRRkagratflpLNKMRDERRDLSILS 594
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 547 ENSERQIKI-------------------------LEQENEHLNQ-----------------TVSSLRQRSQISAEARVKD 584
Cdd:TIGR02169 595 EDGVIGFAVdlvefdpkyepafkyvfgdtlvvedIEAARRLMGKyrmvtlegelfeksgamTGGSRAPRGGILFSRSEPA 674
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 585 IEKEnkiLHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE----ELENELHHLEKENELLQKKITNLKitcEKIEA 660
Cdd:TIGR02169 675 ELQR---LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkigEIEKEIEQLEQEEEKLKERLEELE---EDLSS 748
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 661 LEQENSELEREnrklkktldsfknltfqLESLEKENSQLDEENLELRRNVESLKcASMKMAQLQLENKELESEKEQLKKG 740
Cdd:TIGR02169 749 LEQEIENVKSE-----------------LKELEARIEELEEDLHKLEEALNDLE-ARLSHSRIPEIQAELSKLEEEVSRI 810
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 741 LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSL 820
Cdd:TIGR02169 811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE---AALRDLESRLGDL 887
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 821 EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELvKRATID 900
Cdd:TIGR02169 888 KKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAEL-QRVEEE 966
|
....
gi 1465187875 901 IKTL 904
Cdd:TIGR02169 967 IRAL 970
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
594-1375 |
1.10e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 93.21 E-value: 1.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 594 ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNlkitcEKIEALEQENSELERENR 673
Cdd:TIGR02169 180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALE-----RQKEAIERQLASLEEELE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 674 KLKKTLDSF-KNLTFQLESLEKENSQL----DEENLELRRNVESLKcASMKMAQLQLENKELESEK--EQLKKGLELLKA 746
Cdd:TIGR02169 255 KLTEEISELeKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELE-AEIASLERSIAEKERELEDaeERLAKLEAEIDK 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQknlEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR02169 334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR---DELKDYREKLEKLKREINELKRELDR 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 827 LEKDKKQLEKENKRLRQQAEIK-------DTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKE----LEKENKELVK 895
Cdd:TIGR02169 411 LQEELQRLSEELADLNAAIAGIeakinelEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydrVEKELSKLQR 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 896 RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEI-KEE 974
Cdd:TIGR02169 491 ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELlKRR 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 975 KIAAL------EARLEES-----------------TNYNQQLRQELK------TVKKNYEALKQRQDEERMV-------Q 1018
Cdd:TIGR02169 571 KAGRAtflplnKMRDERRdlsilsedgvigfavdlVEFDPKYEPAFKyvfgdtLVVEDIEAARRLMGKYRMVtlegelfE 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1019 SSPPISGEDNKWERESQETTR---ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1095
Cdd:TIGR02169 651 KSGAMTGGSRAPRGGILFSRSepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1096 QNTTLQTQNAKLQVEnstLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLikDHEKLELLhERQASEye 1175
Cdd:TIGR02169 731 EEEKLKERLEELEED---LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL--SHSRIPEI-QAELSK-- 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1176 sliskhgtLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEkmLLENKNhetvaaeyKKLCGENDRLNHTYS 1255
Cdd:TIGR02169 803 --------LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI--DLKEQI--------KSIEKEIENLNGKKE 864
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1256 QLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLD------ 1329
Cdd:TIGR02169 865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDpkgede 944
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1330 --------------QIQTLMLQNRTLLEQNMESKDLFHVEQRQYidklNELRRQKEKLEE 1375
Cdd:TIGR02169 945 eipeeelsledvqaELQRVEEEIRALEPVNMLAIQEYEEVLKRL----DELKEKRAKLEE 1000
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
497-1282 |
1.49e-18 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 92.73 E-value: 1.49e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLnqtvSSLRQRSQI 576
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLN----EERIDLLQE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 656
Cdd:pfam02463 245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 657 KIEALEQENSELERENRKLKKTLD----SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELE- 731
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEikreAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEe 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 732 ---SEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTlqKNLEELKISSK 808
Cdd:pfam02463 405 keaQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE--DLLKETQLVKL 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKES--CVRLKEL 886
Cdd:pfam02463 483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsaTADEVEE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 887 EKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLK 966
Cdd:pfam02463 563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 967 KSLEIKEEKIAALEARLEESTN--YNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKV 1044
Cdd:pfam02463 643 AKESGLRKGVSLEEGLAEKSEVkaSLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1045 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1124
Cdd:pfam02463 723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1125 NAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELlhERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQ 1204
Cdd:pfam02463 803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK--EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 1205 LLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQ 1282
Cdd:pfam02463 881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
465-895 |
5.56e-18 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 90.46 E-value: 5.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 465 LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQ-LEKTIE 543
Cdd:TIGR04523 234 IEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdWNKELK 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 544 TLRENSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK-- 621
Cdd:TIGR04523 314 SELKNQEKKLEEIQNQISQNNKIISQLNEQIS-QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLEsq 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 622 ---------EKGERAEELENELHHLEKENELLQKKITNLKITCEK----IEALEQENSELERENRKLKKTLDSFKNltfQ 688
Cdd:TIGR04523 393 indleskiqNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKnnseIKDLTNQDSVKELIIKNLDNTRESLET---Q 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 689 LESLEKEnsqLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKterlevsyqgLDIENQRL 768
Cdd:TIGR04523 470 LKVLSRS---INKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK----------LESEKKEK 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 769 QKTLENSNKKIQQLESELQDLEMENQTLQKNleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Cdd:TIGR04523 537 ESKISDLEDELNKDDFELKKENLEKEIDEKN--------KEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEK 608
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 1465187875 849 DTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVK 895
Cdd:TIGR04523 609 EKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
350-1059 |
2.77e-17 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 88.64 E-value: 2.77e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQ-----LKAKLHDMEMERDmdrkkieelmeenmtlEMAQKQsmd 424
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRqsvidLQTKLQEMQMERD----------------AMADIR--- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 425 eslhlgweleqiSRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKtVEELRTTVDSVEGNASKILKMEKENQRLS 504
Cdd:pfam15921 134 ------------RRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ-IEQLRKMMLSHEGVLQEIRSILVDFEEAS 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 505 KKvEILENEIVQEKQSLQNCQNLSKDLMKEKAQL----------EKTIETLRENSERQIK-ILEQENEHLNQTVSS---- 569
Cdd:pfam15921 201 GK-KIYEHDSMSTMHFRSLGSAISKILRELDTEIsylkgrifpvEDQLEALKSESQNKIElLLQQHQDRIEQLISEheve 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 570 ---LRQRSQiSAEARVKDIEKENKILHESIKETSS----KLSKIEFEKRQIKKELEHYKEKGE-RAEELE-------NEL 634
Cdd:pfam15921 280 itgLTEKAS-SARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEdKIEELEkqlvlanSEL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 635 HHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLTFQLESLEKEnsqLDEENLELRRNVESL 713
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLQKLLAdLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE---LDDRNMEVQRLEALL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 714 KC--------ASMKMAQLQLENK----------ELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS 775
Cdd:pfam15921 436 KAmksecqgqMERQMAAIQGKNEslekvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAT 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 776 NKKIQQLES-------ELQDLEMEN---QTLQKNLEELKIS----SKRLEQLEKENKSLEQETSQ-------LEKDKKQL 834
Cdd:pfam15921 516 NAEITKLRSrvdlklqELQHLKNEGdhlRNVQTECEALKLQmaekDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQL 595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 835 EKE--NKRLRQQ-----AEIKDTTLEENNVKIGNLEKENKTLskeIGIYKESCVRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:pfam15921 596 EKEinDRRLELQefkilKDKKDAKIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSL 672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 908 REDLVSEKL----KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLesKLESTLKKSLEIKEEKIAALEARL 983
Cdd:pfam15921 673 SEDYEVLKRnfrnKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAM--KVAMGMQKQITAKRGQIDALQSKI 750
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 984 eestnynQQLRQELKTVKKNYEALKqrQDEERMVQSSPPISGEDNKW--ERESQETTRELLKVKDRLIEVERNNATLQ 1059
Cdd:pfam15921 751 -------QFLEEAMTNANKEKHFLK--EEKNKLSQELSTVATEKNKMagELEVLRSQERRLKEKVANMEVALDKASLQ 819
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
701-1015 |
3.04e-17 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 88.46 E-value: 3.04e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 701 EENL--------ELRRNVESLKcasmKMAQLQLENKELESEKEQLKKGLELLKASFKKTE--RLEVSYQGLDIENQRLQK 770
Cdd:COG1196 185 EENLerledilgELERQLEPLE----RQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAELEELEAELEELEA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 771 TLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELL---AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 851 TLEENNVKIGNLEKENKTLSKEigiykescvrLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Cdd:COG1196 338 ELEELEEELEEAEEELEEAEAE----------LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 931 ELEKIGLNKERLLHDEQSTDDSRYKLLESKLEstLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQR 1010
Cdd:COG1196 408 AEEALLERLERLEEELEELEEALAELEEEEEE--EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE 485
|
....*
gi 1465187875 1011 QDEER 1015
Cdd:COG1196 486 LAEAA 490
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
136-839 |
5.16e-17 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 87.82 E-value: 5.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 136 QKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENvfdlqwmevTDMSQEDIEPLLKNMALHLKRLIDERDEHSETIIELS 215
Cdd:TIGR02169 272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIAS---------LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 216 EERDGLHFLPHASSSAQSpcgspgmKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEN 295
Cdd:TIGR02169 343 REIEEERKRRDKLTEEYA-------ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 296 MNLLSDARSARMyrdELDALREKavrVDKLESEVsrykerlhdiefyKARVEELKEDNQVLLETKTMLEDQLEGTRARSD 375
Cdd:TIGR02169 416 QRLSEELADLNA---AIAGIEAK---INELEEEK-------------EDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 376 KLHELEKENLQLKAKLHDMEMERD------MDRKKIEELMEENMT---LEMAQKQSMDESLHLGWEL------------- 433
Cdd:TIGR02169 477 EYDRVEKELSKLQRELAEAEAQARaseervRGGRAVEEVLKASIQgvhGTVAQLGSVGERYATAIEVaagnrlnnvvved 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 434 -------------EQISRTSEL------SEAPQKSLGHE------------------------------VNELTSS---- 460
Cdd:TIGR02169 557 davakeaiellkrRKAGRATFLplnkmrDERRDLSILSEdgvigfavdlvefdpkyepafkyvfgdtlvVEDIEAArrlm 636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 461 ---RLLKLE---------MENQSLTKTVEELRTTVD--SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Cdd:TIGR02169 637 gkyRMVTLEgelfeksgaMTGGSRAPRGGILFSRSEpaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR 716
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 527 LSKDLMKEKAQLEKTIETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI----LHESIKET 599
Cdd:TIGR02169 717 KIGEIEKEIEQLEQEEEKLKErleELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlSHSRIPEI 796
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 600 SSKLSKIEFEKRQIKKelehykekgeRAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTL 679
Cdd:TIGR02169 797 QAELSKLEEEVSRIEA----------RLREIEQKLNRLTLEKEYLEKEIQELQ---EQRIDLKEQIKSIEKEIENLNGKK 863
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 680 DSFKNltfQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQ 759
Cdd:TIGR02169 864 EELEE---ELEELEAALRDLESRLGDLKKERDELE---AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 760 ---GLDIENQRLQKTLENSNKKIQQLESELQDLEMENqtlQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR02169 938 dpkGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVN---MLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
|
...
gi 1465187875 837 ENK 839
Cdd:TIGR02169 1015 KKR 1017
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-1012 |
1.46e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 86.28 E-value: 1.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnMNLLSDARSARMYRDeldaLREKAVRVDKLESEVSR 331
Cdd:TIGR02169 238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKK-IKDLGEEEQLRVKEK----IGELEAEIASLERSIAE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 332 YKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenlQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR02169 313 KERELEDAE---ERLAKLEAEIDKLLAEIEELEREIEEERKRRD----------KLTEEYAELKEELEDLRAELEEVDKE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 412 NMTLEMAQKQSMDESLHLGWELEQISRTselseapQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRTTVDSVegnAS 491
Cdd:TIGR02169 380 FAETRDELKDYREKLEKLKREINELKRE-------LDRLQEELQRL-SEELADLNAAIAGIEAKINELEEEKEDK---AL 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE---RQIKILEQENEHLNQTVS 568
Cdd:TIGR02169 449 EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggrAVEEVLKASIQGVHGTVA 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 569 SL---RQRSQISAE----ARVKDIEKENKILHESIKE--TSSKLSKIEF----EKRQIKKELEHYKEKG----------- 624
Cdd:TIGR02169 529 QLgsvGERYATAIEvaagNRLNNVVVEDDAVAKEAIEllKRRKAGRATFlplnKMRDERRDLSILSEDGvigfavdlvef 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 625 ---------------------ERAEELENELHHLEKENELLQK-------------KITNLKITCEKIEALEQENSELER 670
Cdd:TIGR02169 609 dpkyepafkyvfgdtlvvediEAARRLMGKYRMVTLEGELFEKsgamtggsraprgGILFSRSEPAELQRLRERLEGLKR 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 671 ENRKLKKTLDSFKNLTFQLESLEKENSQldeENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFKK 750
Cdd:TIGR02169 689 ELSSLQSELRRIENRLDELSQELSDASR---KIGEIEKEIEQLE---QEEEKLKERLEELEEDLSSLEQEIENVKSELKE 762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 751 TERlEVSYQGLDIENqrLQKTLEN-----SNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETS 825
Cdd:TIGR02169 763 LEA-RIEELEEDLHK--LEEALNDlearlSHSRIPEIQAELSKLEEEVSRIEARLREIE---QKLNRLTLEKEYLEKEIQ 836
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKeigiykescvRLKELEKENKElvkratidiktlv 905
Cdd:TIGR02169 837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES----------RLGDLKKERDE------------- 893
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 906 tLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLEsklESTLKKSLEIKEEKIAALEARLEE 985
Cdd:TIGR02169 894 -LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEE---IPEEELSLEDVQAELQRVEEEIRA 969
|
810 820
....*....|....*....|....*..
gi 1465187875 986 STNYNQQLRQELKTVKKNYEALKQRQD 1012
Cdd:TIGR02169 970 LEPVNMLAIQEYEEVLKRLDELKEKRA 996
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
325-935 |
1.48e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 86.27 E-value: 1.48e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 325 LESEVSRYK--ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR 402
Cdd:PRK03918 141 LESDESREKvvRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELR 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 403 KKIEELMEENMTLEmaqkqsmdeslHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRtt 482
Cdd:PRK03918 221 EELEKLEKEVKELE-----------ELKEEIEELEKELESLEGSKRKLEEKIREL-EERIEELKKEIEELEEKVKELK-- 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 483 vdSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKtIETLRENSERQIKILEQENEH 562
Cdd:PRK03918 287 --ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHEL 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 563 LNQTVSSLRQRSQISA----------EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELEN 632
Cdd:PRK03918 364 YEEAKAKKEELERLKKrltgltpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGR 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 633 ELHHlEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEkensQLDEENLELRR-NVE 711
Cdd:PRK03918 444 ELTE-EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAE----QLKELEEKLKKyNLE 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN-KKIQQLESELQDLE 790
Cdd:PRK03918 519 ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELE 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 791 menqTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKigNLEKENKTLS 870
Cdd:PRK03918 599 ----PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYE--ELREEYLELS 672
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1465187875 871 KEIGIYKEscvRLKELEKENKELVKratiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:PRK03918 673 RELAGLRA---ELEELEKRREEIKK----TLEKLKEELEEREKAKKELEKLEKALERVEELREKV 730
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-1075 |
5.02e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 84.73 E-value: 5.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQME---IELKRLQQENMNLLSDA-----RSARMYRDELDALREKAVRVD 323
Cdd:TIGR02169 178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAEryqALLKEKREYEGYELLKEkealeRQKEAIERQLASLEEELEKLT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 324 KLESE-VSRYKERLHDIEFYKARVEELKEDNQVLLETKtMLEDQLEGTRARS------DKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02169 258 EEISElEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEK-IGELEAEIASLERsiaekeRELEDAEERLAKLEAEIDKLLA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 397 ERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTS-----ELSEAPQK--SLGHEVNELTSSRLLKLEmEN 469
Cdd:TIGR02169 337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdELKDYREKleKLKREINELKRELDRLQE-EL 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 470 QSLTKTVEELRTTVDSVEGnasKILKMEKENQRLSKKVEILEneivqekqslQNCQNLSKDLMKEKAQLEKTIETLREnS 549
Cdd:TIGR02169 416 QRLSEELADLNAAIAGIEA---KINELEEEKEDKALEIKKQE----------WKLEQLAADLSKYEQELYDLKEEYDR-V 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 550 ERQIKILEQENEHLNQTVSSLRQRsQISAEARVKDIEKENKILHESIKE---------------TSSKLSKIEFEKRQIK 614
Cdd:TIGR02169 482 EKELSKLQRELAEAEAQARASEER-VRGGRAVEEVLKASIQGVHGTVAQlgsvgeryataievaAGNRLNNVVVEDDAVA 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 615 KELEHY--KEKGERAEELE-NELHHLEKENELLQKK-----ITNLKITCEKIEA---------LEQENSELEREnrklkk 677
Cdd:TIGR02169 561 KEAIELlkRRKAGRATFLPlNKMRDERRDLSILSEDgvigfAVDLVEFDPKYEPafkyvfgdtLVVEDIEAARR------ 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 678 TLDSFKNLTFQLESLEKENS----------------QLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKkgl 741
Cdd:TIGR02169 635 LMGKYRMVTLEGELFEKSGAmtggsraprggilfsrSEPAELQRLRERLEGLK---RELSSLQSELRRIENRLDELS--- 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 742 ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE--ELKISSKRLEQLEKENKS 819
Cdd:TIGR02169 709 QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEelEEDLHKLEEALNDLEARL 788
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 820 LEQETSQLEKDKKQLEKENKRLRQQaeikdttLEENNVKIGNLEKENKTLSKEIgiyKESCVRLKELEKENKELVKRati 899
Cdd:TIGR02169 789 SHSRIPEIQAELSKLEEEVSRIEAR-------LREIEQKLNRLTLEKEYLEKEI---QELQEQRIDLKEQIKSIEKE--- 855
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 900 dIKTLVTLREDLVSEKLKTQQMNNDLEKlthelEKIGLNKERLLHDEQstddsrYKLLESKLEsTLKKSLEIKEEKIAAL 979
Cdd:TIGR02169 856 -IENLNGKKEELEEELEELEAALRDLES-----RLGDLKKERDELEAQ------LRELERKIE-ELEAQIEKKRKRLSEL 922
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 980 EARLEESTNYNQQLRQELKTVKKNYEAL-------KQRQDEERMVQSSPPIsgeDNKWERESQEttrellkVKDRLIEVE 1052
Cdd:TIGR02169 923 KAKLEALEEELSEIEDPKGEDEEIPEEElsledvqAELQRVEEEIRALEPV---NMLAIQEYEE-------VLKRLDELK 992
|
890 900
....*....|....*....|...
gi 1465187875 1053 RNNATLQAEKQALKTQLKQLETQ 1075
Cdd:TIGR02169 993 EKRAKLEEERKAILERIEEYEKK 1015
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
497-1073 |
5.25e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 84.22 E-value: 5.25e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ--RS 574
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARleQD 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEhykEKGERAEELENELHHLEKENELLQKKITnlkit 654
Cdd:COG1196 304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE---EAEEELEEAEAELAEAEEALLEAEAELA----- 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 655 cEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEK 734
Cdd:COG1196 376 -EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE------EEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQT--LQKNLEELKISSKRLEQ 812
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkAALLLAGLRGLAGAVAV 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 813 LEKENKSLEQ---------------ETSQLEKDKKQLEKENKRLR----QQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Cdd:COG1196 529 LIGVEAAYEAaleaalaaalqnivvEDDEVAAAAIEYLKAAKAGRatflPLDKIRARAALAAALARGAIGAAVDLVASDL 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSR 953
Cdd:COG1196 609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 954 YKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERE 1033
Cdd:COG1196 689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 1465187875 1034 SQETTRELlkvkDRLIEVernN-------ATLQAEKQALKTQLKQLE 1073
Cdd:COG1196 769 LERLEREI----EALGPV---NllaieeyEELEERYDFLSEQREDLE 808
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
730-1321 |
6.50e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 83.96 E-value: 6.50e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 730 LESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKR 809
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqAEIKDttLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKE 889
Cdd:PRK03918 240 IEELEKELESLEGSKRKLEEKIRELEERIEELK--KEIEE--LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 890 NKELVKRATIDIKTLVTLREdlvseklktqqMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLE-SKLESTLK-K 967
Cdd:PRK03918 316 LSRLEEEINGIEERIKELEE-----------KEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEElERLKKRLTgL 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 968 SLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISG---EDNKWERESQETTRELLKV 1044
Cdd:PRK03918 385 TPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRI 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1045 KDRLIEVErnnatlqAEKQALKTQLKQLETqnnnlqaqILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1124
Cdd:PRK03918 465 EKELKEIE-------EKERKLRKELRELEK--------VLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEK 529
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1125 NAQLLIQqssLENENESVIKEREDLKSLYDSLIKDHEKLELLhERQASEYESLISKHGTlkSAHKNLEVEHRDLE---DR 1201
Cdd:PRK03918 530 LKEKLIK---LKGEIKSLKKELEKLEELKKKLAELEKKLDEL-EEELAELLKELEELGF--ESVEELEERLKELEpfyNE 603
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1202 YNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSqllketevlQTDHKNLKSLLNNSKLE 1281
Cdd:PRK03918 604 YLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS---------EEEYEELREEYLELSRE 674
|
570 580 590 600
....*....|....*....|....*....|....*....|
gi 1465187875 1282 QTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLE 1321
Cdd:PRK03918 675 LAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
626-1351 |
7.06e-16 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 83.53 E-value: 7.06e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 626 RAEELENELHHLEKENELLQKKITNL-KITCEKIEALEQENSELErenrKLKKTLDSFKNltfqleSLEKENSQLDEENL 704
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLdKNLNKDEEKINNSNNKIK----ILEQQIKDLND------KLKKNKDKINKLNS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 705 ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSyqgLDIENQRLQKTLENSNKKIQQLES 784
Cdd:TIGR04523 104 DLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEK---LNNKYNDLKKQKEELENELNLLEK 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK 864
Cdd:TIGR04523 181 EKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKD 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 865 ENKTLskeigiykescvrLKELEKENKELVKRATidiktlvtlredlvseklKTQQMNNDLEKLTHELEKigLNKERllh 944
Cdd:TIGR04523 261 EQNKI-------------KKQLSEKQKELEQNNK------------------KIKELEKQLNQLKSEISD--LNNQK--- 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 945 deqstddsrykllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKnyealkqrqdeermvqssppis 1024
Cdd:TIGR04523 305 -------------EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK---------------------- 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1025 gEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQN 1104
Cdd:TIGR04523 350 -ELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEI 428
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1105 AKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTL 1184
Cdd:TIGR04523 429 ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKEL 508
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1185 KSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMlLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVL 1264
Cdd:TIGR04523 509 EEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD-DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEK 587
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1265 QTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQ 1344
Cdd:TIGR04523 588 QELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKK 667
|
....*..
gi 1465187875 1345 NMESKDL 1351
Cdd:TIGR04523 668 IKESKTK 674
|
|
| HkD_Hook |
cd22222 |
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes ... |
15-163 |
8.90e-16 |
|
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes Hook1-3. Hook1 is a microtubule-binding protein required for spermatid differentiation. Hook2, also a microtubule-binding protein, contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. Hook adaptor proteins share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain, and contacts the helix alpha1 of dynein light intermediate chain 1 (LIC1) in a hydrophobic groove.
Pssm-ID: 411793 Cd Length: 147 Bit Score: 76.13 E-value: 8.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 15 TSPLVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKLESQ----RVNKKVNNDASLRMHNLSILVRQIKFYY 90
Cdd:cd22222 1 CDSLLQWLQTFN-LIAPHATAED----LSDGVAIAQVLNQIDPEYFSDswlsKIKPDVGDNWRLKVSNLKKILKGIVDYY 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1465187875 91 QETL-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22222 76 SEVLgQQISGFTMPDVNAIAEK----EDPKELGRLLQLVLGCAVNCERKEEYIQAIMGLEESVQHVVMEAIQEL 145
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
309-1185 |
4.49e-15 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 81.65 E-value: 4.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 309 RDELDALREKAVRVDKLESEVSRYKERLH----DIEFYKARVEELKEDNQ-VLLETKTMLEDQLEGTRARsdkLHELEKE 383
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRrereKAERYQALLKEKREYEGyELLKEKEALERQKEAIERQ---LASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTL---EMAQKQSMDESLHLgwELEQISRTSELSEAPQKSLghevneltSS 460
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeEQLRVKEKIGELEA--EIASLERSIAEKERELEDA--------EE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 461 RLLKLEMENQSLTKTVEELRTtvdSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK 540
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELER---EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKR 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 541 TIETLRENSERQI---KILEQENEHLNQTVSSLRQRsQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK--- 614
Cdd:TIGR02169 400 EINELKRELDRLQeelQRLSEELADLNAAIAGIEAK-INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKeey 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 615 ----KELehykekgeraEELENELHHLEKENELLQKKITNLKITCEKIEALEQ----ENSELERENRKLKKTLDS----- 681
Cdd:TIGR02169 479 drveKEL----------SKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgTVAQLGSVGERYATAIEVaagnr 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 682 FKNLTFQLESLEKENSQ-LDEENL---------ELRRNVESLKCASMKMAQLQLEN-KELESEKEQLKK---GLELLKAS 747
Cdd:TIGR02169 549 LNNVVVEDDAVAKEAIElLKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDlVEFDPKYEPAFKyvfGDTLVVED 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 748 FKKTERLEVSYQGLDIENQRLQKT-----------LENSNK-----KIQQLESELQDLEMENQTLQKNLEELKissKRLE 811
Cdd:TIGR02169 629 IEAARRLMGKYRMVTLEGELFEKSgamtggsraprGGILFSrsepaELQRLRERLEGLKRELSSLQSELRRIE---NRLD 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEscvrlkelekenk 891
Cdd:TIGR02169 706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEE------------- 772
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 892 elvkratidiktlvtlredlvseklktqqmnnDLEKLTHELEKIglnkerllhdEQSTDDSRYKLLESKLEStLKKSLEI 971
Cdd:TIGR02169 773 --------------------------------DLHKLEEALNDL----------EARLSHSRIPEIQAELSK-LEEEVSR 809
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 972 KEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERESQETTRELLKVKDRLIEV 1051
Cdd:TIGR02169 810 IEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN--LNGKKEELEEELEELEAALRDLESRLGDL 887
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1052 ERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAqLLIQ 1131
Cdd:TIGR02169 888 KKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQR-VEEE 966
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|....
gi 1465187875 1132 QSSLENENESVIKEREDLKSLYDSLIKDHEKLellhERQASEYESLISKHGTLK 1185
Cdd:TIGR02169 967 IRALEPVNMLAIQEYEEVLKRLDELKEKRAKL----EEERKAILERIEEYEKKK 1016
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
556-1318 |
7.38e-15 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 80.55 E-value: 7.38e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 556 LEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETSSKLSKIEFEKRQIkkeLEHYKEKGERAEELENELH 635
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELH----EKQKFYLRQSVIDLQTKLQEMQMERDAM---ADIRRRESQSQEDLRNQLQ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 636 HLEKENELLQkkitnlkitCEKIEALEQENSELErenrKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKC 715
Cdd:pfam15921 149 NTVHELEAAK---------CLKEDMLEDSNTQIE----QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHF 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 716 ASMKMAQLQLEnKELESEKEQLK-------KGLELLKA-SFKKTERLEVSYQgldienQRLQKTLENSNKKIQQLESELQ 787
Cdd:pfam15921 216 RSLGSAISKIL-RELDTEISYLKgrifpveDQLEALKSeSQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKAS 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 788 DLEMENQTLQKNLEELKISSKR-----LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:pfam15921 289 SARSQANSIQSQLEIIQEQARNqnsmyMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQF 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 863 EKENKTLSKEI-GIYKESCVRLKEL--EKE-NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKiglN 938
Cdd:pfam15921 369 SQESGNLDDQLqKLLADLHKREKELslEKEqNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQG---Q 445
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 939 KERLLHDEQSTDDSRYKL--LESKLEST---LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVK-KNYEALKQRQD 1012
Cdd:pfam15921 446 MERQMAAIQGKNESLEKVssLTAQLESTkemLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEaTNAEITKLRSR 525
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1013 EERMVQSSPPISGEDNKWERESQETTRELLKV--KDRLIEVERNNATLQAE--------KQALKTQLKQLETQNNNLQaq 1082
Cdd:pfam15921 526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMaeKDKVIEILRQQIENMTQlvgqhgrtAGAMQVEKAQLEKEINDRR-- 603
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1083 iLALQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEK 1162
Cdd:pfam15921 604 -LELQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEV 678
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1163 LELLHERQASEYESLISK-HGTLKSAHKNLEVEHRDLEDR--------------YNQLLKQKGQLEDLEKMLKVEQEKML 1227
Cdd:pfam15921 679 LKRNFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMegsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEAMT 758
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1228 LENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLN 1307
Cdd:pfam15921 759 NANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
|
810
....*....|..
gi 1465187875 1308 NQCEL-LSQLKG 1318
Cdd:pfam15921 839 LQHTLdVKELQG 850
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
252-943 |
1.34e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 79.98 E-value: 1.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 252 ELADAKAKIRRLRQELEEKTEQLldckqeleqmeielKRLQQEnmnllsdARSARMYRdeldALREKAVRVDkLESEVSR 331
Cdd:COG1196 180 KLEATEENLERLEDILGELERQL--------------EPLERQ-------AEKAERYR----ELKEELKELE-AELLLLK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 332 YKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRArsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRL---ELEELELELEEAQAEEYELLAELARLEQDIARLEER 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 412 NMTLEMAQKQsmdeslhLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgnas 491
Cdd:COG1196 311 RRELEERLEE-------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE---- 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Cdd:COG1196 380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 572 QRSQISAEARVKDIEKENKILHESIKEtSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEEL-AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 652 KITCEKIEALEQENSELERENRKLKKTLDSFKN--LTFQLESLEKENSQLDEENLELRRN------VESLKCASMKMAQL 723
Cdd:COG1196 539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGaavdlvASDLREADARYYVL 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 724 QLENKELESEKEQLKKGLELLKASfkkTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Cdd:COG1196 619 GDTLLGRTLVAARLEAALRRAVTL---AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN----KTLSKEIGIYKEs 879
Cdd:COG1196 696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppdlEELERELERLER- 774
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1465187875 880 cvRLKELEK-------ENKELVKRATidikTLVTLREDLVSEKlktqqmnNDLEKLTHELEKIGlnKERLL 943
Cdd:COG1196 775 --EIEALGPvnllaieEYEELEERYD----FLSEQREDLEEAR-------ETLEEAIEEIDRET--RERFL 830
|
|
| HOOK_N |
pfam19047 |
HOOK domain; This domain is found at the N-terminus of HOOK proteins. |
18-163 |
1.41e-14 |
|
HOOK domain; This domain is found at the N-terminus of HOOK proteins.
Pssm-ID: 465958 Cd Length: 151 Bit Score: 72.83 E-value: 1.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 18 LVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKLES----QRVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:pfam19047 6 LLTWLQTFN-VPAPCATVED----LTDGVAMAQVLHQIDPSWFTeawlSRIKEDVGDNWRLKVSNLKKILQSVVDYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1465187875 94 L-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:pfam19047 81 LgQQISDFLLPDVNLIGEH----SDPAELGRLLQLILGCAVNCEKKQEYIQQIMTLEESVQHVVMTAIQEL 147
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
313-828 |
1.68e-14 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 79.31 E-value: 1.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 313 DALREKAVRVDKLESEVSRYKER-LHD--------IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Cdd:PRK02224 180 RVLSDQRGSLDQLKAQIEEKEEKdLHErlngleseLAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDEslhlgweleqisrtSELSEAPQKSLghevneltSSRLL 463
Cdd:PRK02224 260 IEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE--------------AGLDDADAEAV--------EARRE 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 464 KLEMENQSLTKTVEELRTTV----DSVEGNASKILKMEKENQRLSKKVEILENEivqekqsLQNCQNLSKDLMKEKAQLE 539
Cdd:PRK02224 318 ELEDRDEELRDRLEECRVAAqahnEEAESLREDADDLEERAEELREEAAELESE-------LEEAREAVEDRREEIEELE 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 540 KTIETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEK---ENKILHE------------------S 595
Cdd:PRK02224 391 EEIEELRErfgDAPVDLGNAEDFLEELREERDELREREA-ELEATLRTARErveEAEALLEagkcpecgqpvegsphveT 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAEEL---ENELHHLEKENELLQKKITNLKITC----EKIEALEQENSEL 668
Cdd:PRK02224 470 IEEDRERVEELEAELEDLEEEVEEVEERLERAEDLveaEDRIERLEERREDLEELIAERRETIeekrERAEELRERAAEL 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 669 ERENR----KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL 744
Cdd:PRK02224 550 EAEAEekreAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERL 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 745 KASFKKTERLEVSYQGLDIENQRLQKtlENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQET 824
Cdd:PRK02224 630 AEKRERKRELEAEFDEARIEEAREDK--ERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRV 707
|
....
gi 1465187875 825 SQLE 828
Cdd:PRK02224 708 EALE 711
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
339-1065 |
7.58e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.49 E-value: 7.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 339 IEFYKA----RVEELKE--DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEN 412
Cdd:PTZ00121 1018 IDFNQNfnieKIEELTEygNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF 1097
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 413 MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKlEMENQSLTKTVEELRTTVDSVEGNASK 492
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE-DAKRVEIARKAEDARKAEEARKAEDAK 1176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 493 ILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ---ENEHLNQTVSS 569
Cdd:PTZ00121 1177 KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaEEERNNEEIRK 1256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 570 LRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGE---RAEELENELHHLEKENELLQK 646
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEeakKADEAKKKAEEAKKKADAAKK 1336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 647 KIT------------------NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDE------- 701
Cdd:PTZ00121 1337 KAEeakkaaeaakaeaeaaadEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElkkaaaa 1416
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 702 --ENLELRRNVESLKCA--SMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIEN-QRLQKTLENSN 776
Cdd:PTZ00121 1417 kkKADEAKKKAEEKKKAdeAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKaDEAKKKAEEAK 1496
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 777 KKIQQL----ESELQDLEMENQTLQKNLEELKIS--SKRLEQLEK-ENKSLEQETSQLEKDKKQLEKENKRLRQQAEiKD 849
Cdd:PTZ00121 1497 KKADEAkkaaEAKKKADEAKKAEEAKKADEAKKAeeAKKADEAKKaEEKKKADELKKAEELKKAEEKKKAEEAKKAE-ED 1575
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 850 TTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRAtiDIKTLVTLREDLVSEKLKTQQMNNDLEKLT 929
Cdd:PTZ00121 1576 KNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE--ELKKAEEEKKKVEQLKKKEAEEKKKAEELK 1653
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 930 HELEKIGLNKERLLHDEQStddsrykllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1009
Cdd:PTZ00121 1654 KAEEENKIKAAEEAKKAEE---------DKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKA 1724
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 1465187875 1010 RQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQAL 1065
Cdd:PTZ00121 1725 EEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
256-1097 |
8.24e-14 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 77.39 E-value: 8.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 256 AKAKIRRLRQELEEKTEQLLDCKQELEQMEIEL----KRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSR 331
Cdd:TIGR00606 187 ALETLRQVRQTQGQKVQEHQMELKYLKQYKEKAceirDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 332 YKERLHDIEFYKARVEELKED-NQVLLETKTMLEDQL-EGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELM 409
Cdd:TIGR00606 267 LDNEIKALKSRKKQMEKDNSElELKMEKVFQGTDEQLnDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 410 EENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGH-EVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEG 488
Cdd:TIGR00606 347 VEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQE 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 489 NASKI-LKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL---SKDLMKEKAQLEKTIETL---RENS------------ 549
Cdd:TIGR00606 427 QADEIrDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLegsSDRILELDQELRKAERELskaEKNSltetlkkevksl 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 550 -------ERQIKILEQENEHLNQTVSSLRQ-----RSQISAEARVKDIEKENKILHESI-------KETSSKLSKIEFEK 610
Cdd:TIGR00606 507 qnekadlDRKLRKLDQEMEQLNHHTTTRTQmemltKDKMDKDEQIRKIKSRHSDELTSLlgyfpnkKQLEDWLHSKSKEI 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 611 RQIKKELEHYKEKGERAEELEnelHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ-- 688
Cdd:TIGR00606 587 NQTRDRLAKLNKELASLEQNK---NHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGAta 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 689 -----LESLEKENS----------QLDEENLELRRNVES-LKCASMKMAQLQLENKELESEKEQLKKGLE----LLKASF 748
Cdd:TIGR00606 664 vysqfITQLTDENQsccpvcqrvfQTEAELQEFISDLQSkLRLAPDKLKSTESELKKKEKRRDEMLGLAPgrqsIIDLKE 743
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ---DLEMENQTLQKNLEELKISSKRLEQLEKENKS--LEQE 823
Cdd:TIGR00606 744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEEsakVCLTDVTIMERFQMELKDVERKIAQQAAKLQGsdLDRT 823
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Cdd:TIGR00606 824 VQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIRE 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 904 LVTLRED---LVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALE 980
Cdd:TIGR00606 904 IKDAKEQdspLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVN 983
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 981 ARLEESTNYNQQLRQELKTVKKNYEALKQRqdeERMVQSSPPISGEDNKWeRESQETTRELLKV--KDRLIEVERNNATL 1058
Cdd:TIGR00606 984 AQLEECEKHQEKINEDMRLMRQDIDTQKIQ---ERWLQDNLTLRKRENEL-KEVEEELKQHLKEmgQMQVLQMKQEHQKL 1059
|
890 900 910
....*....|....*....|....*....|....*....
gi 1465187875 1059 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1097
Cdd:TIGR00606 1060 EENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRD 1098
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
616-1383 |
2.23e-13 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 75.78 E-value: 2.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 616 ELEHYKEKGERAEELEnelhhlEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Cdd:pfam02463 164 GSRLKRKKKEALKKLI------EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 696 NSQLDEENLELRRNVESLKCASMKMAQ--LQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLE 773
Cdd:pfam02463 238 RIDLLQELLRDEQEEIESSKQEIEKEEekLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLK 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 774 NSNKKIQQLESELQDLEMENQTLQKNLEELKIS-SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:pfam02463 318 ESEKEKKKAEKELKKEKEEIEELEKELKELEIKrEAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 853 EENNVKIGNLEKENKTLSKEIGIYKEscvRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHEL 932
Cdd:pfam02463 398 ELKSEEEKEAQLLLELARQLEDLLKE---EKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 933 EKIGLNKERLLHDEQSTDDSRYKLLESKLEST-LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQ 1011
Cdd:pfam02463 475 KETQLVKLQEQLELLLSRQKLEERSQKESKARsGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVS 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1012 DEERMV--QSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:pfam02463 555 ATADEVeeRQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1090 TVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEllhER 1169
Cdd:pfam02463 635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREK---EE 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1170 QASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDR 1249
Cdd:pfam02463 712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEE 791
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1250 LNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLnnqcELLSQLKGNLEEENRHLLD 1329
Cdd:pfam02463 792 KEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKL----EKLAEEELERLEEEITKEE 867
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....
gi 1465187875 1330 QIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKF 1383
Cdd:pfam02463 868 LLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEE 921
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
477-829 |
2.35e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.86 E-value: 2.35e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 477 EELRTTVDSVEgnaSKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQIKIL 556
Cdd:TIGR02168 680 EELEEKIEELE---EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQL 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKiLHESIKETSSKLSKIEFEKRQIKKEL----EHYKEKGERAEELEN 632
Cdd:TIGR02168 753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEE-LEAQIEQLKEELKALREALDELRAELtllnEEAANLRERLESLER 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 633 ELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNL----TFQLESLEKENSQLDEENLELRR 708
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELS---EDIESLAAEIEELEELIEELESELEALLNEraslEEALALLRSELEELSEELRELES 908
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 709 NVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFkkTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQD 788
Cdd:TIGR02168 909 KRSELR---RELEELREKLAQLELRLEGLEVRIDNLQERL--SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1465187875 789 LEMENQTlqkNLEELKISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:TIGR02168 984 LGPVNLA---AIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
340-1177 |
9.79e-13 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 73.85 E-value: 9.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 340 EFYKARVEELKEDNQVL--LETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK--IEELMEENMTL 415
Cdd:pfam02463 166 RLKRKKKEALKKLIEETenLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLklNEERIDLLQEL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 416 EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILK 495
Cdd:pfam02463 246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 496 MEKENQRLSKKVEILENEI-VQEKQSLQN---CQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Cdd:pfam02463 326 AEKELKKEKEEIEELEKELkELEIKREAEeeeEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 572 QRSQISAEARVKDIEKENKILhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Cdd:pfam02463 406 EAQLLLELARQLEDLLKEEKK-EELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN---LELRRNVESLKCASMKMAQLQLENK 728
Cdd:pfam02463 485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVaveNYKVAISTAVIVEVSATADEVEERQ 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 729 ELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQR-LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS 807
Cdd:pfam02463 565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILnLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELE 887
Cdd:pfam02463 645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 888 KENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE-KLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLK 966
Cdd:pfam02463 725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEeEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 967 KSLEIKEEKIAALEARLEEStnyNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQEttRELLKVKD 1046
Cdd:pfam02463 805 ALEEELKEEAELLEEEQLLI---EQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQE--LLLKEEEL 879
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1047 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTS----LM 1122
Cdd:pfam02463 880 EEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENnkeeEE 959
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....*
gi 1465187875 1123 NQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESL 1177
Cdd:pfam02463 960 ERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEE 1014
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
257-836 |
1.31e-12 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 73.13 E-value: 1.31e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 257 KAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDEL-DALREKAVRVDKLESEVSRYKER 335
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLeKEKLNIQKNIDKIKNKLLKLELL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 336 LHDIEFY-------KARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKK 404
Cdd:TIGR04523 203 LSNLKKKiqknkslESQISELKKQNNQLKDNIEKKQQEINEKTTEisntQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 405 IEELMEENMTLEMA-----QKQSMDESLHLGWELEQISRT-----SELSEAPQK--SLGHEVNELTSSrLLKLEMENQSL 472
Cdd:TIGR04523 283 IKELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKleeiqNQISQNNKIisQLNEQISQLKKE-LTNSESENSEK 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 473 TKTVEElrttvdsvegNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQ 552
Cdd:TIGR04523 362 QRELEE----------KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL----EKE 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 553 IKILEQENEHLNQTVSSLRqrSQISA-EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELehyKEKGERAEELE 631
Cdd:TIGR04523 428 IERLKETIIKNNSEIKDLT--NQDSVkELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL---KSKEKELKKLN 502
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 632 NELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSfKNLTFQLESLEKENSQLDEENLELRRNVE 711
Cdd:TIGR04523 503 EEKKELEEKVKDLTKKISSLK---EKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKEIEELKQTQK 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 712 SLKcasMKMAQLQLENKELESEKEQLKKGLEL-----------LKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 780
Cdd:TIGR04523 579 SLK---KKQEEKQELIDQKEKEKKDLIKEIEEkekkisslekeLEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1465187875 781 QLESELQDLEMENQTLQKNLEEL---------------------KISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR04523 656 EIRNKWPEIIKKIKESKTKIDDIielmkdwlkelslhykkyitrMIRIKDLPKLEEKYKEIEKELKKLDEFSKELEN 732
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
369-751 |
4.76e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 71.63 E-value: 4.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 369 GTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQK 448
Cdd:TIGR02168 671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 449 SLGHEVNELTSSRLLKLEM--ENQSLTKTVEELRTTVDsvegnaSKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Cdd:TIGR02168 751 QLSKELTELEAEIEELEERleEAEEELAEAEAEIEELE------AQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 527 LSKDLMKEKAQLEKTIETLRENSER---QIKILEQENEHLNQTVSSLRQRSQI------SAEARVKDIEKENKILHESIK 597
Cdd:TIGR02168 825 RLESLERRIAATERRLEDLEEQIEElseDIESLAAEIEELEELIEELESELEAllneraSLEEALALLRSELEELSEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 598 ETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELhhLEKENELLQkkiTNLKITCEKIEALEQENSELERENRKLKK 677
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYS---LTLEEAEALENKIEDDEEEARRRLKRLEN 979
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 678 TLDSFKNLTF----QLESLEKENSQLDEENLELRRNVESLKCASMKMaqlqleNKELeseKEQLKKGLELLKASFKKT 751
Cdd:TIGR02168 980 KIKELGPVNLaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI------DREA---RERFKDTFDQVNENFQRV 1048
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
244-713 |
6.39e-12 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 70.84 E-value: 6.39e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 244 ESRQHLSV---ELADAKAKIRR-------LRQELEEKTEQLLDCKQELEQM--EIELKRLQQENMNLLSDARSARmyRDE 311
Cdd:PRK02224 248 ERREELETleaEIEDLRETIAEterereeLAEEVRDLRERLEELEEERDDLlaEAGLDDADAEAVEARREELEDR--DEE 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 312 L-DALREKAVRVDKLESEVSRYKERLHDIEfykARVEELKEDNQVLletKTMLEDQLEGTRARSDKLHELEKENLQLKAK 390
Cdd:PRK02224 326 LrDRLEECRVAAQAHNEEAESLREDADDLE---ERAEELREEAAEL---ESELEEAREAVEDRREEIEELEEEIEELRER 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 391 LHDMEMER-------DMDRKKIEELMEENMTLEmAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL 463
Cdd:PRK02224 400 FGDAPVDLgnaedflEELREERDELREREAELE-ATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVE 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 464 KLEMENQSLTKTVEELRTTVDSVEgnasKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Cdd:PRK02224 479 ELEAELEDLEEEVEEVEERLERAE----DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAE 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 544 TLRENSERQikilEQENEHLNQTVSSLRQRSQISAEArvkdIEKENKI--LHESIKETSSKLSKIEfEKRQIKKEL---- 617
Cdd:PRK02224 555 EKREAAAEA----EEEAEEAREEVAELNSKLAELKER----IESLERIrtLLAAIADAEDEIERLR-EKREALAELnder 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 618 -EHYKEKGERAEELENELH--HLEKENELLQKKITNLKITCEKIEALEQENSELE----------RENRKLKKTLDSFKN 684
Cdd:PRK02224 626 rERLAEKRERKRELEAEFDeaRIEEAREDKERAEEYLEQVEEKLDELREERDDLQaeigavenelEELEELRERREALEN 705
|
490 500 510
....*....|....*....|....*....|....
gi 1465187875 685 LTFQLESLEKENSQLDEENLELR-----RNVESL 713
Cdd:PRK02224 706 RVEALEALYDEAEELESMYGDLRaelrqRNVETL 739
|
|
| HkD_Hook2 |
cd22227 |
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a ... |
18-163 |
1.58e-11 |
|
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a microtubule-binding protein that contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook2 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411798 Cd Length: 150 Bit Score: 64.13 E-value: 1.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 18 LVTWVKTFGPLAAGNgtnldEYVALVDGVFLNQVMLQINPKLES----QRVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:cd22227 6 LLTWLQTFQVPSPCS-----SYQDLTSGVAIAQVLNRIDPSWFNeawlGRIKEDTGDNWRLKVSNLKKILQSLLEYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1465187875 94 L-QQLIMMSLPNVLIIGKnpFSEqgTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22227 81 LgHQVSEDHLPDVNLIGE--FSD--DTELGKLLQLVLGCAISCEKKQEHIQQIMTLEESVQHVVMEAIQEL 147
|
|
| HkD_Hook3 |
cd22226 |
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein ... |
18-163 |
1.77e-11 |
|
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook3 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411797 Cd Length: 153 Bit Score: 64.22 E-value: 1.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 18 LVTWVKTFGPLAAGngTNLDEyvaLVDGVFLNQVMLQINPKLESQ----RVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:cd22226 9 LLTWIQTFNVDAPC--QTVED---LTSGVVMAQVLQKIDPAYFDEnwlnRIKTEVGDNWRLKISNLKKILKGILDYNHEI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1465187875 94 L-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22226 84 LgQQINDFTLPDVNLIGEH----SDAAELGRMLQLILGCAVNCEQKQEYIQTIMMMEESVQHVVMTAIQEL 150
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
257-1377 |
2.40e-11 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 69.31 E-value: 2.40e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 257 KAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNL----LSDARSARMYRDELDALReKAVRVDKLESEVSRY 332
Cdd:TIGR01612 557 KKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYInklkLELKEKIKNISDKNEYIK-KAIDLKKIIENNNAY 635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 333 KERLHDIEFYKArVEELKEDNQVLLETKTMLEDQLEGTRAR-----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEE 407
Cdd:TIGR01612 636 IDELAKISPYQV-PEHLKNKDKIYSTIKSELSKIYEDDIDAlynelSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQN 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 408 LMEENMTLEMAQKQSMDESL---------HLGWEL-EQISRTSELSEAPQKSLGHEVNELTSSR-----------LLKLE 466
Cdd:TIGR01612 715 METATVELHLSNIENKKNELldiiveikkHIHGEInKDLNKILEDFKNKEKELSNKINDYAKEKdelnkykskisEIKNH 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 467 MENQSLTKTV--EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD-LMKEKAQLEKTIE 543
Cdd:TIGR01612 795 YNDQINIDNIkdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEkIDSEHEQFAELTN 874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 544 TLR-ENSERQIKILEQE----NEHLNQTVSSLRQRSQ-ISAEARVKDIEKENKILHESIKETSSKLSKIefeKRQIKKEL 617
Cdd:TIGR01612 875 KIKaEISDDKLNDYEKKfndsKSLINEINKSIEEEYQnINTLKKVDEYIKICENTKESIEKFHNKQNIL---KEILNKNI 951
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 618 EHYKEKGERAEELENELhhlekENELLQKKITNLKITCE-KIEALEQENSELERENRKLKKTLDSFKN--LTFQLESLEK 694
Cdd:TIGR01612 952 DTIKESNLIEKSYKDKF-----DNTLIDKINELDKAFKDaSLNDYEAKNNELIKYFNDLKANLGKNKEnmLYHQFDEKEK 1026
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 695 ENSQLDEENLELRRNVESLKCA---SMKMAQLQLEN---KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRL 768
Cdd:TIGR01612 1027 ATNDIEQKIEDANKNIPNIEIAihtSIYNIIDEIEKeigKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDFGKEEN 1106
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 769 QKTLENSNKKiqqleseLQDLEMENQTLQKNLEELKISSKRLEQLEKENKSleqETSQLEK---------DKKQLEKENK 839
Cdd:TIGR01612 1107 IKYADEINKI-------KDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKA---QINDLEDvadkaisndDPEEIEKKIE 1176
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 840 RLRQQAEIKDTTLEENN---VKIGNLEKENKTLSKEIGI---YKESCVRLKeLEKENKElVKRATIDIKTLVTLREDLVS 913
Cdd:TIGR01612 1177 NIVTKIDKKKNIYDEIKkllNEIAEIEKDKTSLEEVKGInlsYGKNLGKLF-LEKIDEE-KKKSEHMIKAMEAYIEDLDE 1254
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 914 EKLKTQQMNNDLEKltheleKIGLNKERLLHDEQSTDDSRYKLLESKLESTL----KKSLEIKEEKI---------AALE 980
Cdd:TIGR01612 1255 IKEKSPEIENEMGI------EMDIKAEMETFNISHDDDKDHHIISKKHDENIsdirEKSLKIIEDFSeesdindikKELQ 1328
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 981 ARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQssppISGEDNKWERESQETTRELLKvKDRLIEVERNNATLQA 1060
Cdd:TIGR01612 1329 KNLLDAQKHNSDINLYLNEIANIYNILKLNKIKKIIDE----VKEYTKEIEENNKNIKDELDK-SEKLIKKIKDDINLEE 1403
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1061 EKQALKTqlkQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ--LLIQQSSLENE 1138
Cdd:TIGR01612 1404 CKSKIES---TLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQhiLKIKKDNATND 1480
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1139 ---NESVIKERED----LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLK------SAHKNLEVEHRDLEDRYNQL 1205
Cdd:TIGR01612 1481 hdfNINELKEHIDkskgCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAiknkfaKTKKDSEIIIKEIKDAHKKF 1560
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1206 LKQKGQLEdlEKMLKVEQEKMLLENKnhetvaaeykklCGENDRLNHTYSQLLKETEVLQTDH---KNLKSLLNNSKLEQ 1282
Cdd:TIGR01612 1561 ILEAEKSE--QKIKEIKKEKFRIEDD------------AAKNDKSNKAAIDIQLSLENFENKFlkiSDIKKKINDCLKET 1626
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1283 TRLEAEFSKLK--EQYQQLDITSTKLNNQCELLSQLKG---NLEEENRHlLDQIQTLMLQNRTLLEQNMESKDLFHVEQR 1357
Cdd:TIGR01612 1627 ESIEKKISSFSidSQDTELKENGDNLNSLQEFLESLKDqkkNIEDKKKE-LDELDSEIEKIEIDVDQHKKNYEIGIIEKI 1705
|
1210 1220
....*....|....*....|..
gi 1465187875 1358 QYIDKLN--ELRRQKEKLEEKI 1377
Cdd:TIGR01612 1706 KEIAIANkeEIESIKELIEPTI 1727
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
252-1089 |
2.43e-11 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 69.05 E-value: 2.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEqmeielkrlqqenmnllsdarsarmyrDELDALREKAVRVDKLESEVSR 331
Cdd:pfam01576 223 QIAELQAQIAELRAQLAKKEEELQAALARLE---------------------------EETAQKNNALKKIRELEAQISE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 332 YKERLHDIEFYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLK------AKLHDMEME--RDMDR 402
Cdd:pfam01576 276 LQEDLESERAARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKkaleeeTRSHEAQLQemRQKHT 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 403 KKIEELMEE-------NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKT 475
Cdd:pfam01576 356 QALEELTEQleqakrnKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-QARLSESERQRAELAEK 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 476 VEELRTTVDSVEGNASkilKMEKENQRLSKKVEILENEivqekqsLQNCQNLSKDLMKEKAQLEKtieTLRENSERQIKI 555
Cdd:pfam01576 435 LSKLQSELESVSSLLN---EAEGKNIKLSKDVSSLESQ-------LQDTQELLQEETRQKLNLST---RLRQLEDERNSL 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 556 LEQENEHLNQTVSSLRQRSqiSAEARVKDIEKEnkilhesIKETSSKLSKIEFEKRQIKKELEhykEKGERAEELENELH 635
Cdd:pfam01576 502 QEQLEEEEEAKRNVERQLS--TLQAQLSDMKKK-------LEEDAGTLEALEEGKKRLQRELE---ALTQQLEEKAAAYD 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 636 HLEKENELLQKKITNLKItceKIEALEQENSELERENRKLKKTLDSFKNLTFQL---------ESLEKENSQLD-----E 701
Cdd:pfam01576 570 KLEKTKNRLQQELDDLLV---DLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerdraeaEAREKETRALSlaralE 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 702 ENLELRRNVESlkcaSMKMAQLQLEN-------------------KELESEKEQLKKGLELLKASFKKTE----RLEVSY 758
Cdd:pfam01576 647 EALEAKEELER----TNKQLRAEMEDlvsskddvgknvhelerskRALEQQVEEMKTQLEELEDELQATEdaklRLEVNM 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 759 QGLDIENQR-LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE--------QLEKENKSLEQETSQLEK 829
Cdd:pfam01576 723 QALKAQFERdLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQLKK 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 830 DK---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIyKESCVRLKELEKE-------NKELVKRATI 899
Cdd:pfam01576 803 LQaqmKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGASGKSALQ 881
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 900 DIK-----TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG--LNKERLL---------HDEQSTDDSRYKL--LESKL 961
Cdd:pfam01576 882 DEKrrleaRIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTteLAAERSTsqksesarqQLERQNKELKAKLqeMEGTV 961
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 962 ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL-KTVKKNYEALKQRQDEERMVQssppisgednKWERESQETTRE 1040
Cdd:pfam01576 962 KSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVrRTEKKLKEVLLQVEDERRHAD----------QYKDQAEKGNSR 1031
|
890 900 910 920
....*....|....*....|....*....|....*....|....*....
gi 1465187875 1041 LLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:pfam01576 1032 MKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSK 1080
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
182-801 |
3.16e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 68.99 E-value: 3.16e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 182 SQEDIEPLLKNMALHLKRLIDErdeHSETIIELSEERDGlhflphASSSAQSPCGSPGMKRTESRQHLSV---ELADAKA 258
Cdd:pfam15921 254 SQNKIELLLQQHQDRIEQLISE---HEVEITGLTEKASS------ARSQANSIQSQLEIIQEQARNQNSMymrQLSDLES 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 259 KIRRLRQELEEKTEQLLDCKQELEqmeielKRLQQENmnllSDARSARMYRDEL--------DALREKAVRVDKLESEVS 330
Cdd:pfam15921 325 TVSQLRSELREAKRMYEDKIEELE------KQLVLAN----SELTEARTERDQFsqesgnldDQLQKLLADLHKREKELS 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 331 RYKE---RLHD--------IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL-HDMEMER 398
Cdd:pfam15921 395 LEKEqnkRLWDrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLtAQLESTK 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 399 DMDRKKIEELMEENMTLEMAQKQSMDeslhLGWELEQISRTSELSEApqkslghEVNELTSSRLLKLEmENQSLTKTVEE 478
Cdd:pfam15921 475 EMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERAIEATNA-------EITKLRSRVDLKLQ-ELQHLKNEGDH 542
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 479 LRTTvdSVEGNASKILKMEKEnqrlsKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETlRENSERQIKILEQ 558
Cdd:pfam15921 543 LRNV--QTECEALKLQMAEKD-----KVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND-RRLELQEFKILKD 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 559 ENEhlnqtvSSLRQrsqisAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKekgeraeeleNELHHLE 638
Cdd:pfam15921 615 KKD------AKIRE-----LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSR----------NELNSLS 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 639 KENELLQKKITN----LKITCEKIE-ALEQENSELERENRKLKK-----------TLDSFKNLTF---QLESLEKENSQL 699
Cdd:pfam15921 674 EDYEVLKRNFRNkseeMETTTNKLKmQLKSAQSELEQTRNTLKSmegsdghamkvAMGMQKQITAkrgQIDALQSKIQFL 753
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 700 DEENLELRRNVESLKCASMKMAQlqlENKELESEKEQLKKGLELLKAsfkKTERLEVSYQGLDIENQRLQKTLENSNKKI 779
Cdd:pfam15921 754 EEAMTNANKEKHFLKEEKNKLSQ---ELSTVATEKNKMAGELEVLRS---QERRLKEKVANMEVALDKASLQFAECQDII 827
|
650 660
....*....|....*....|..
gi 1465187875 780 QQLESELQDLEMENQTLQKNLE 801
Cdd:pfam15921 828 QRQEQESVRLKLQHTLDVKELQ 849
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
252-1013 |
3.19e-11 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 68.92 E-value: 3.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMyRDELDALREKAVRVDKLESEVSR 331
Cdd:TIGR00606 320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLAT-RLELDGFERGPFSERQIKNFHTL 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 332 YKERLHDIEFYKAR-VEELKEDNQVLLETKTMLEDQLEGT-RARSDKLHELEKENLQLKAKLHDME-MERDMDR--KKIE 406
Cdd:TIGR00606 399 VIERQEDEAKTAAQlCADLQSKERLKQEQADEIRDEKKGLgRTIELKKEILEKKQEELKFVIKELQqLEGSSDRilELDQ 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 407 ELMEENMTLEMAQKQSMDESL-----HLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL--KLEMENQSLTKTVEEL 479
Cdd:TIGR00606 479 ELRKAERELSKAEKNSLTETLkkevkSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLtkDKMDKDEQIRKIKSRH 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 480 RTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN------SERQI 553
Cdd:TIGR00606 559 SDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEE 638
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 554 KILEQENEHLNQtvsSLRQRSQISAEARVKDiekenKILHESIKETSS------KLSKIEFEKRQIKKELEH-YKEKGER 626
Cdd:TIGR00606 639 SDLERLKEEIEK---SSKQRAMLAGATAVYS-----QFITQLTDENQSccpvcqRVFQTEAELQEFISDLQSkLRLAPDK 710
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 627 AEELENELHHLEKENELLqkkITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNltfqleSLEKENSQLDEENLEL 706
Cdd:TIGR00606 711 LKSTESELKKKEKRRDEM---LGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN------DIEEQETLLGTIMPEE 781
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 707 RrNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF------KKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 780
Cdd:TIGR00606 782 E-SAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRtvqqvnQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQ 860
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 781 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQqaeikdttleENNVKIG 860
Cdd:TIGR00606 861 HLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQ----------EKEELIS 930
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 861 NLEKENKTLSKEIGIYKESCVR----LKELEKENKELVKRATIDIKT-LVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:TIGR00606 931 SKETSNKKAQDKVNDIKEKVKNihgyMKDIENKIQDGKDDYLKQKETeLNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ 1010
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1465187875 936 GLnKERLLHDEQSTDDSRYKLLEskLESTLKKSL-EIKEEKIAalearleESTNYNQQLRQELKTVKKNYEALKQRQDE 1013
Cdd:TIGR00606 1011 KI-QERWLQDNLTLRKRENELKE--VEEELKQHLkEMGQMQVL-------QMKQEHQKLEENIDLIKRNHVLALGRQKG 1079
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
201-669 |
4.89e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 68.14 E-value: 4.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 201 IDERDEHSETIIELSEERDGLhflphasssaqspcgspGMKRTESRQHLSVELADAKAkIRRLRQELEEKTEQ----LLD 276
Cdd:PRK02224 271 EREREELAEEVRDLRERLEEL-----------------EEERDDLLAEAGLDDADAEA-VEARREELEDRDEElrdrLEE 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 277 CKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD--------ALREKAVRVDKLESEVSRYKERLHDIEFYKARVEE 348
Cdd:PRK02224 333 CRVAAQAHNEEAESLREDADDLEERAEELREEAAELEseleeareAVEDRREEIEELEEEIEELRERFGDAPVDLGNAED 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 349 LKEDnqvLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDM-----------DRKKIEELMEENMTLEm 417
Cdd:PRK02224 413 FLEE---LREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVegsphvetieeDRERVEELEAELEDLE- 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 418 AQKQSMDESLHLGWEL-EQISRTSELSEapQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKilkM 496
Cdd:PRK02224 489 EEVEEVEERLERAEDLvEAEDRIERLEE--RREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAE---A 563
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSkDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576
Cdd:PRK02224 564 EEEAEEAREEVAELNSKLAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAE 642
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKenellqkkitnlkiTCE 656
Cdd:PRK02224 643 FDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALEN--------------RVE 708
|
490
....*....|...
gi 1465187875 657 KIEALEQENSELE 669
Cdd:PRK02224 709 ALEALYDEAEELE 721
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
136-847 |
5.98e-11 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 68.07 E-value: 5.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 136 QKKEEFIERIQGLD-FDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPL---LKNMALHLKRLIDERDEHSETI 211
Cdd:TIGR00618 163 KEKKELLMNLFPLDqYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYherKQVLEKELKHLREALQQTQQSH 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 212 IELSEERDGLHflphASSSAQSPCGSPgMKRTESRQHLSVELADAKAKIRRLRQ--ELEEKTEQLLDCKQELEQMEIELK 289
Cdd:TIGR00618 243 AYLTQKREAQE----EQLKKQQLLKQL-RARIEELRAQEAVLEETQERINRARKaaPLAAHIKAVTQIEQQAQRIHTELQ 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 290 RLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEG 369
Cdd:TIGR00618 318 SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 370 TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDeslhlgwelEQISRTSELSEAPQKS 449
Cdd:TIGR00618 398 LCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQ---------CEKLEKIHLQESAQSL 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 450 LGHEVNELTSSRLLKLEMEnqslTKTVEElrttvdsvegnasKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 529
Cdd:TIGR00618 469 KEREQQLQTKEQIHLQETR----KKAVVL-------------ARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQ 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 530 DLMKEKAQLEKTIETLRE--NSER-QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Cdd:TIGR00618 532 RGEQTYAQLETSEEDVYHqlTSERkQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLA 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 607 EfEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEAL---EQENSELERENRKLKKTLDSFK 683
Cdd:TIGR00618 612 C-EQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALsirVLPKELLASRQLALQKMQSEKE 690
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 684 NLTFQLESLEKENSQLDEEN---LELRRNVESLKCASMKM-----AQLQLENKELESEKEQLKKGL-ELLKASFKKTERL 754
Cdd:TIGR00618 691 QLTYWKEMLAQCQTLLRELEthiEEYDREFNEIENASSSLgsdlaAREDALNQSLKELMHQARTVLkARTEAHFNNNEEV 770
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 755 EVSYQgLDIENQRLQKTLENSNKKIQQLESELQDLEMENQT------LQKNLEELKISSKR---LEQLEKENKSLEQETS 825
Cdd:TIGR00618 771 TAALQ-TGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeipsdeDILNLQCETLVQEEeqfLSRLEEKSATLGEITH 849
|
730 740
....*....|....*....|..
gi 1465187875 826 QLEKDKKQLEKENKRLRQQAEI 847
Cdd:TIGR00618 850 QLLKYEECSKQLAQLTQEQAKI 871
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
638-1076 |
6.25e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 67.49 E-value: 6.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 638 EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLkcas 717
Cdd:COG4717 53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL---- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 718 mkmaQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI-QQLESELQDLEMENQTL 796
Cdd:COG4717 129 ----PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEEL 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 797 QKNLEELKissKRLEQLEKENKSLEQETSQLEkDKKQLEKENKRLRQQAEI------------KDTTLEENNVKIGN--- 861
Cdd:COG4717 205 QQRLAELE---EELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLlliaaallallgLGGSLLSLILTIAGvlf 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 862 ------------LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLT 929
Cdd:COG4717 281 lvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 930 HELEKIGLNKER--LLHDEQSTDDSRYkllESKLEstLKKSLEIKEEKIAALEARLEESTNYNQ---------QLRQELK 998
Cdd:COG4717 361 EELQLEELEQEIaaLLAEAGVEDEEEL---RAALE--QAEEYQELKEELEELEEQLEELLGELEellealdeeELEEELE 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 999 TVKKNYEALKQRQDEERMVQSSppISGEDNKWE--RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN 1076
Cdd:COG4717 436 ELEEELEELEEELEELREELAE--LEAELEQLEedGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
585-1241 |
8.30e-11 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 67.05 E-value: 8.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 585 IEKENKILHESIKETSSKLS---KIEFEKRQIKKELEHYKEK-GERAEELENELHHLEKENELLQKKITNLKITCEKiEA 660
Cdd:pfam05483 90 IKKWKVSIEAELKQKENKLQenrKIIEAQRKAIQELQFENEKvSLKLEEEIQENKDLIKENNATRHLCNLLKETCAR-SA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 661 LEQENSELERE---------NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVES--LKCASMKMAQLQLENKE 729
Cdd:pfam05483 169 EKTKKYEYEREetrqvymdlNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEeyKKEINDKEKQVSLLLIQ 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 730 LESEKEQLKKGLELLKASFKKTERLEvsyqgldiENQRLQ-KTLENSNKKIQQLESELQDLEMENQ---TLQKNLEE-LK 804
Cdd:pfam05483 249 ITEKENKMKDLTFLLEESRDKANQLE--------EKTKLQdENLKELIEKKDHLTKELEDIKMSLQrsmSTQKALEEdLQ 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 805 ISSKRLEQLEKENKSLEQETSQLEKDKK----QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIgiykESC 880
Cdd:pfam05483 321 IATKTICQLTEEKEAQMEELNKAKAAHSfvvtEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSEL----EEM 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 881 VRLKElekeNKELVKRatiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD--EQSTDDSRYKLLE 958
Cdd:pfam05483 397 TKFKN----NKEVELE---ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDleIQLTAIKTSEEHY 469
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 959 SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE-----LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERE 1033
Cdd:pfam05483 470 LKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEasdmtLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDE 549
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1034 SQETTRELLK----VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ----TQNA 1105
Cdd:pfam05483 550 LESVREEFIQkgdeVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKkkgsAENK 629
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1106 KLQVENSTLNSQSTSL---------MNQNAQLLIQQSSLENENesVIKEREDLKSLYDSLIKDHEKLEL----------- 1165
Cdd:pfam05483 630 QLNAYEIKVNKLELELasakqkfeeIIDNYQKEIEDKKISEEK--LLEEVEKAKAIADEAVKLQKEIDKrcqhkiaemva 707
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1166 LHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYN-QLLKQKGQLEDLEKMLKV---EQEKMLLENKNHETVAAEYK 1241
Cdd:pfam05483 708 LMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEiELSNIKAELLSLKKQLEIekeEKEKLKMEAKENTAILKDKK 787
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
261-1124 |
1.05e-10 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 67.12 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARsarmyrDELDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:pfam01576 211 RKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLE------EETAQKNNALKKIRELEAQISELQEDLESER 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 341 FYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLK------AKLHDMEME--RDMDRKKIEELMEE 411
Cdd:pfam01576 285 AARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKkaleeeTRSHEAQLQemRQKHTQALEELTEQ 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 412 -------NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRTTVD 484
Cdd:pfam01576 365 leqakrnKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-QARLSESERQRAELAEKLSKLQSELE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 485 SVEGNASKIlkmEKENQRLSKKVEILENEivqekqsLQNCQNLSKDLMKEKAQLEKTietLRENSERQIKILEQENEHLN 564
Cdd:pfam01576 444 SVSSLLNEA---EGKNIKLSKDVSSLESQ-------LQDTQELLQEETRQKLNLSTR---LRQLEDERNSLQEQLEEEEE 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 565 QTVSSLRQRSqiSAEARVKDIEKEnkilhesIKETSSKLSKIEFEKRQIKKELEhykEKGERAEELENELHHLEKENELL 644
Cdd:pfam01576 511 AKRNVERQLS--TLQAQLSDMKKK-------LEEDAGTLEALEEGKKRLQRELE---ALTQQLEEKAAAYDKLEKTKNRL 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 645 QKKITNLKItceKIEALEQENSELERENRKLKKTLDSFKNLTFQL---------ESLEKENSQLD-----EENLELRRNV 710
Cdd:pfam01576 579 QQELDDLLV---DLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerdraeaEAREKETRALSlaralEEALEAKEEL 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 711 ESlkcaSMKMAQLQLEN-------------------KELESEKEQLKKGLELLKASFKKTE----RLEVSYQGLDIENQR 767
Cdd:pfam01576 656 ER----TNKQLRAEMEDlvsskddvgknvhelerskRALEQQVEEMKTQLEELEDELQATEdaklRLEVNMQALKAQFER 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 768 -LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE--------QLEKENKSLEQETSQLEKDK---KQLE 835
Cdd:pfam01576 732 dLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQLKKLQaqmKDLQ 811
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 836 KENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIyKESCVRLKELEKE-------NKELVKRATIDIK-----T 903
Cdd:pfam01576 812 RELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGASGKSALQDEKrrleaR 890
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG--LNKERLLhdEQSTDDSRYKLlesklestlkksleikEEKIAALEA 981
Cdd:pfam01576 891 IAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTteLAAERST--SQKSESARQQL----------------ERQNKELKA 952
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 982 RLEEstnYNQQLRQELKTVKKNYEAlKQRQDEERMVQSSppisgednkweRESQETTRELLKVKDRLIEVernnaTLQAE 1061
Cdd:pfam01576 953 KLQE---MEGTVKSKFKSSIAALEA-KIAQLEEQLEQES-----------RERQAANKLVRRTEKKLKEV-----LLQVE 1012
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1062 KQalKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVE-------NSTLNSQSTSLMNQ 1124
Cdd:pfam01576 1013 DE--RRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRElddatesNESMNREVSTLKSK 1080
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
263-586 |
1.24e-10 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 66.25 E-value: 1.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 263 LRQELEEKTEQLL-------DCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKER 335
Cdd:pfam05622 64 LQKQLEQLQEENFrletardDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDILRESSDKVKKLEATVETYKKK 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 336 LHDIEFYKARVEELKEDNQVLLETKTMLED----------QLEGTRARSDKLH-----------ELEKENLQLKAKLHDM 394
Cdd:pfam05622 144 LEDLGDLRRQVKLLEERNAEYMQRTLQLEEelkkanalrgQLETYKRQVQELHgklseeskkadKLEFEYKKLEEKLEAL 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 395 EMERDMDRKKIEELMEENMTLEMAQKQSMdeslhlgwELEQISRTSELSEAPQKSLGHEVNEL-TSSRLLKLEMENQSL- 472
Cdd:pfam05622 224 QKEKERLIIERDTLRETNEELRCAQLQQA--------ELSQADALLSPSSDPGDNLAAEIMPAeIREKLIRLQHENKMLr 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 473 ---TKTVEELRTTVDSVEGNASKIL-KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE- 547
Cdd:pfam05622 296 lgqEGSYRERLTELQQLLEDANRRKnELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKLHEa 375
|
330 340 350
....*....|....*....|....*....|....*....
gi 1465187875 548 NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Cdd:pfam05622 376 QSELQKKKEQIEELEPKQDSNLAQKIDELQEALRKKDED 414
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
419-1053 |
1.36e-10 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 66.46 E-value: 1.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 419 QKQSMDESLhlgwELEQISRTSELSEAPQKSLGHEVneltsSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKmek 498
Cdd:PRK01156 151 RKKILDEIL----EINSLERNYDKLKDVIDMLRAEI-----SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLK--- 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 499 ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL-RQRSQIS 577
Cdd:PRK01156 219 EIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVyKNRNYIN 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 578 AEARVK-DIEKENKILhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNlkitce 656
Cdd:PRK01156 299 DYFKYKnDIENKKQIL-SNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKS------ 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 657 kieaLEQENSELERENRKLKKTLDsfknltFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Cdd:PRK01156 372 ----IESLKKKIEEYSKNIERMSA------FISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDE 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 737 LKKGLELLKAsfkkteRLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKE 816
Cdd:PRK01156 442 LSRNMEMLNG------QSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLK---KRKEYLESE 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 817 N-KSLEQETSQLEKDKKQLEKEnkrlrqqaEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEscvrlkelEKENKELVK 895
Cdd:PRK01156 513 EiNKSINEYNKIESARADLEDI--------KIKINELKDKHDKYEEIKNRYKSLKLEDLDSKR--------TSWLNALAV 576
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 896 RATIDIKTLVTlREDLVSEKLktqqmnNDLEKLTHELEKiglnkerLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEK 975
Cdd:PRK01156 577 ISLIDIETNRS-RSNEIKKQL------NDLESRLQEIEI-------GFPDDKSYIDKSIREIENEANNLNNKYNEIQENK 642
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 976 IAAlearleestnynQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVER 1053
Cdd:PRK01156 643 ILI------------EKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILR 708
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
241-559 |
1.99e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.23 E-value: 1.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREK-A 319
Cdd:TIGR02168 667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQlE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 320 VRVDKLESEVSRYKERlhdIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDME 395
Cdd:TIGR02168 747 ERIAQLSKELTELEAE---IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElkalREALDELRAELTLLNEEAANLR 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 396 MERDMDRKKIEELMEEnmtLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSsrllkLEMENQSLTKT 475
Cdd:TIGR02168 824 ERLESLERRIAATERR---LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS-----LEEALALLRSE 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 476 VEELRTTVDSVEgnaSKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQ----NLSKDLMKEKAQLEKTIETLRENSER 551
Cdd:TIGR02168 896 LEELSEELRELE---SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQerlsEEYSLTLEEAEALENKIEDDEEEARR 972
|
....*...
gi 1465187875 552 QIKILEQE 559
Cdd:TIGR02168 973 RLKRLENK 980
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1036-1371 |
2.35e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 65.73 E-value: 2.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1036 ETTRE-LLKVKDRLIEVERNNATL--QAEK----QALKTQLKQLEtqnnnlqAQILALQRQTVSLQeqnttLQTQNAKLQ 1108
Cdd:COG1196 182 EATEEnLERLEDILGELERQLEPLerQAEKaeryRELKEELKELE-------AELLLLKLRELEAE-----LEELEAELE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1109 VENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYEsliskhgTLKSAH 1188
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE-------RLEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1189 KNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDH 1268
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1269 KNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmLQNRTLLEQNMES 1348
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL-LEEAALLEAALAE 481
|
330 340
....*....|....*....|...
gi 1465187875 1349 KDLFHVEQRQYIDKLNELRRQKE 1371
Cdd:COG1196 482 LLEELAEAAARLLLLLEAEADYE 504
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
456-877 |
2.81e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 65.17 E-value: 2.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 456 ELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEK--QSLQNCQNLSKDLMK 533
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 534 EKAQLEKTIETLRENsERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQI 613
Cdd:COG4717 147 RLEELEERLEELREL-EEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 614 KKELEHYKEKGERAEELEnELHHLE--------------KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTL 679
Cdd:COG4717 226 EEELEQLENELEAAALEE-RLKEARlllliaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 680 DSFKNLTfQLESLEKE--NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKkglelLKASFKKTERLEVS 757
Cdd:COG4717 305 EELQALP-ALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ-----LEELEQEIAALLAE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 758 YQGLDIE----NQRLQKTLENSNKKIQQLESELQDL--EMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:COG4717 379 AGVEDEEelraALEQAEEYQELKEELEELEEQLEELlgELEELLEALDEEELE---EELEELEEELEELEEELEELREEL 455
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 1465187875 832 KQLEKENKRLRqqaeiKDTTLEENNVKIGNLEKENKTLSKEIGIYK 877
Cdd:COG4717 456 AELEAELEQLE-----EDGELAELLQELEELKAELRELAEEWAALK 496
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
259-695 |
4.38e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.79 E-value: 4.38e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 259 KIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAvrvdKLESEVSRYKERLHD 338
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELE----ALEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 339 IEFYKARVEELKEDNQVLLETKTMLEDQLEgtRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEmA 418
Cdd:COG4717 151 LEERLEELRELEEELEELEAELAELQEELE--ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE-E 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 419 QKQSMDESLHLGWELEQISRTSELSEAPQKSLGHevnELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEK 498
Cdd:COG4717 228 ELEQLENELEAAALEERLKEARLLLLIAAALLAL---LGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 499 ENQRLSKKVEILENEIVQE-KQSLQNCQNLSKDLMKEK-AQLEKTIETLRENSERQIKILEQENEHlnqtvsslrQRSQI 576
Cdd:COG4717 305 EELQALPALEELEEEELEElLAALGLPPDLSPEELLELlDRIEELQELLREAEELEEELQLEELEQ---------EIAAL 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 577 SAEARVKDIEKENKIL--HESIKETSSKLSKIEFEKRQIKKELEHYKEKGERaEELENELHHLEKENELLQKKITNLKit 654
Cdd:COG4717 376 LAEAGVEDEEELRAALeqAEEYQELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELR-- 452
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 1465187875 655 cEKIEALEQENSELERENRkLKKTLDSFKNLTFQLESLEKE 695
Cdd:COG4717 453 -EELAELEAELEQLEEDGE-LAELLQELEELKAELRELAEE 491
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
434-1045 |
4.54e-10 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 64.74 E-value: 4.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 434 EQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQ--SLTKTVEELRTTVDSVEGNAskilKMEKEN-QRLSKKVEIL 510
Cdd:pfam05483 219 EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKmkDLTFLLEESRDKANQLEEKT----KLQDENlKELIEKKDHL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENE-------HLNQTVSSLRQRSQiSAEARVK 583
Cdd:pfam05483 295 TKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAahsfvvtEFEATTCSLEELLR-TEQQRLE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITcekIEALEQ 663
Cdd:pfam05483 374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFL---LQAREK 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 664 ENSELEREnrkLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVEslkcasmkmaQLQLENKELESEKEQLKkglel 743
Cdd:pfam05483 451 EIHDLEIQ---LTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCD----------KLLLENKELTQEASDMT----- 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 744 lkasfkkterLEVSYQGLDIENQRLQKtlENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK-RLEQLEKENKSLEQ 822
Cdd:pfam05483 513 ----------LELKKHQEDIINCKKQE--ERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKcKLDKSEENARSIEY 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 823 ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLkELEKEN-----KELVKRA 897
Cdd:pfam05483 581 EVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKL-ELELASakqkfEEIIDNY 659
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 898 TIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKerllhdeqstdDSRYKLLESKLESTLKKSLEIKEEKIA 977
Cdd:pfam05483 660 QKEIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDKRCQHK-----------IAEMVALMEKHKHQYDKIIEERDSELG 728
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 978 ALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMvqssppisgEDNKWERESQETTRELLKVK 1045
Cdd:pfam05483 729 LYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKE---------EKEKLKMEAKENTAILKDKK 787
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
766-1081 |
5.81e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.57 E-value: 5.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 766 QRLQKTLENsnKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQA 845
Cdd:COG1196 216 RELKEELKE--LEAELLLLKLRELEAELEELEAELEELE---AELEELEAELAELEAELEELRLELEELELELEEAQAEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 846 EIKDTTLEEnnvkignLEKENKTLSKEIgiyKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL 925
Cdd:COG1196 291 YELLAELAR-------LEQDIARLEERR---RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 926 EKLTHELEkiglNKERLLHDEQSTDDSRYKLLESKL--ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKN 1003
Cdd:COG1196 361 AEAEEALL----EAEAELAEAEEELEELAEELLEALraAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 1004 YEALKQRQDEERmvqssppisGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA 1081
Cdd:COG1196 437 EEEEEEALEEAA---------EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
580-1245 |
5.87e-10 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 64.71 E-value: 5.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 580 ARVKDIEKENKILHESIKETSsKLSKIEFEKRQIKKELEHYK-----EKGERAEELENELHHLE--KENELLQKKITNLK 652
Cdd:COG5022 810 KEYRSYLACIIKLQKTIKREK-KLRETEEVEFSLKAEVLIQKfgrslKAKKRFSLLKKETIYLQsaQRVELAERQLQELK 888
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 653 ITCEKIEALEQENSELERENRKLKKTLDS--FKNLTFQLESLEKENSQLDEENLELrrnveslkcASMKMAQLQLENKEL 730
Cdd:COG5022 889 IDVKSISSLKLVNLELESEIIELKKSLSSdlIENLEFKTELIARLKKLLNNIDLEE---------GPSIEYVKLPELNKL 959
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 731 ESEKEQLKKglellkasfkkterlevsyqgldienqrLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRL 810
Cdd:COG5022 960 HEVESKLKE----------------------------TSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGAL 1011
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTtleennvkIGNLEKENKTLSKE---IGIYKESCVRLKELE 887
Cdd:COG5022 1012 QESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKL--------KGLLLLENNQLQARykaLKLRRENSLLDDKQL 1083
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 888 K-----ENKEL-VKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLN-----KERLLHDEQSTDDSRYKL 956
Cdd:COG5022 1084 YqlestENLLKtINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNtlepvFQKLSVLQLELDGLFWEA 1163
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 957 LESKLEST--LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQS--------SPPISGE 1026
Cdd:COG5022 1164 NLEALPSPppFAALSEKRLYQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISegwvpteySTSLKGF 1243
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1027 DNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQ-----EQNTTLQ 1101
Cdd:COG5022 1244 NNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKsatevNYNSEEL 1323
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1102 tQNAKLQVENSTLNSQSTSLMnQNAQLLiqqsslenenESVIKEREDLKSLYDSL--IKDHEKLELLHERQASEYEslis 1179
Cdd:COG5022 1324 -DDWCREFEISDVDEELEELI-QAVKVL----------QLLKDDLNKLDELLDACysLNPAEIQNLKSRYDPADKE---- 1387
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1465187875 1180 kHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQlEDLEKMLKvEQEKMLLENKNHETVAAEYKKLCG 1245
Cdd:COG5022 1388 -NNLPKEILKKIEALLIKQELQLSLEGKDETE-VHLSEIFS-EEKSLISLDRNSIYKEEVLSSLSA 1450
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
729-1117 |
6.70e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.32 E-value: 6.70e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 729 ELESEKEqlkKGLELLKASFKKTERLEVSyqgLDIENQRLQKTLENSNKKI--QQLESELQDLEmenqtlqknleeLKIS 806
Cdd:TIGR02169 167 EFDRKKE---KALEELEEVEENIERLDLI---IDEKRQQLERLRREREKAEryQALLKEKREYE------------GYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL-EKENKTLSKEIGIYKESCVRLKE 885
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLER 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 886 LEKENKELVKRATIDIKTLVTLREDLVSEKlktqqmnndlEKLTHELEkiglnkerllhdeqstddsRYKLLESKLESTL 965
Cdd:TIGR02169 309 SIAEKERELEDAEERLAKLEAEIDKLLAEI----------EELEREIE-------------------EERKRRDKLTEEY 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 966 KKsleiKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEermvqssppISGEDNKWERESQETTRELLKVK 1045
Cdd:TIGR02169 360 AE----LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE---------LKRELDRLQEELQRLSEELADLN 426
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 1046 DRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQ 1117
Cdd:TIGR02169 427 AAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1026-1288 |
6.99e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.19 E-value: 6.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1026 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA-------QILALQRQTVSLQEQNT 1098
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRR 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1099 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLI 1178
Cdd:COG1196 313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1179 SKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKmllENKNHETVAAEYKKLCGENDRLNHTYSQLL 1258
Cdd:COG1196 393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE---EEEALEEAAEEEAELEEEEEALLELLAELL 469
|
250 260 270
....*....|....*....|....*....|
gi 1465187875 1259 KETEVLQTDHKNLKSLLNNSKLEQTRLEAE 1288
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
568-1010 |
7.90e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.02 E-value: 7.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 568 SSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Cdd:COG4717 45 AMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 648 ITNLKItCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEn 727
Cdd:COG4717 125 LQLLPL-YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE- 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 728 kELESEKEQLKKGLELLKASFKKTERlevsyqglDIENQRLQKTLENSNKKIQQLE------SELQDLEMENQTLQKNLE 801
Cdd:COG4717 203 -ELQQRLAELEEELEEAQEELEELEE--------ELEQLENELEAAALEERLKEARlllliaAALLALLGLGGSLLSLIL 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 802 ELK--------ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE---KENKTLS 870
Cdd:COG4717 274 TIAgvlflvlgLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLdriEELQELL 353
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 871 KEIGIYKEScVRLKELEKENKELVKRAtiDIKTLVTLREdLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD 950
Cdd:COG4717 354 REAEELEEE-LQLEELEQEIAALLAEA--GVEDEEELRA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEE 429
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1465187875 951 -DSRYKLLESKLEStLKKSLEIKEEKIAALEARLE--ESTNYNQQLRQELKTVKKNYEALKQR 1010
Cdd:COG4717 430 lEEELEELEEELEE-LEEELEELREELAELEAELEqlEEDGELAELLQELEELKAELRELAEE 491
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
203-872 |
1.04e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.01 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 203 ERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTES-RQHLSVELADAKAKIRRLRQELEE--KTEQLLDCKQ 279
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEkKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 280 ELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELK----EDNQ 354
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAeAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKkkaeEDKK 1405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 355 VLLETKTMLEDQLEGTRARsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELE 434
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAK--KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 435 QISRTSELSEAPQKSlghevneltSSRLLKLEMENqsltKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEI 514
Cdd:PTZ00121 1484 KADEAKKKAEEAKKK---------ADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 515 VQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHE 594
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE 1630
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 595 SIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSElERENRK 674
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEK---KAAEALKKEAEE-AKKAEE 1706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 675 LKKTLDSFKNLTFQLESLEKENSQLDEenlELRRNVESLKcasmKMAQlQLENKELESEKEQLKKGLELLKASFKKTERL 754
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAE---EAKKEAEEDK----KKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 755 EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQL 834
Cdd:PTZ00121 1779 AVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNN 1858
|
650 660 670
....*....|....*....|....*....|....*...
gi 1465187875 835 EKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Cdd:PTZ00121 1859 ENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKD 1896
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
533-878 |
1.44e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 63.22 E-value: 1.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 533 KEKAQLEKTIETLRENSERQIKileqENEHLNQTVSSLRQRSQISAEARVKDIE------KENKILHESIKETSSKLSKI 606
Cdd:pfam05557 27 RARIELEKKASALKRQLDRESD----RNQELQKRIRLLEKREAEAEEALREQAElnrlkkKYLEALNKKLNEKESQLADA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 607 EFEKRQIKKELEHYKEKGERAE----ELENELHHLEKENELLQKKITNLKITCEKIEALEQENS-------ELERENRKL 675
Cdd:pfam05557 103 REVISCLKNELSELRRQIQRAElelqSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAeaeqrikELEFEIQSQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 676 KKTLDSFKNLTFQLES---LEKENSQLDEENLELRRNVESlkcasmkmaqlqleNKELESEKEQLKKGLELLKASFKKTE 752
Cdd:pfam05557 183 EQDSEIVKNSKSELARipeLEKELERLREHNKHLNENIEN--------------KLLLKEEVEDLKRKLEREEKYREEAA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 753 RLEVsyqgldienqrlqktlensnkKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK-------SLEQETS 825
Cdd:pfam05557 249 TLEL---------------------EKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIvlkeensSLTSSAR 307
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 1465187875 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE 878
Cdd:pfam05557 308 QLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRA 360
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
521-873 |
1.49e-09 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 62.61 E-value: 1.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE--ARVKDIEKENKILHESIKE 598
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREkhEELEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 599 TSSKLSKIEFEKRQIKKELEH-YKEKGERAEELENELHHLEKEnellQKKITNLKitcekiealEQENSELERENRKLKK 677
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEdIKTLTQRVLERETELERMKER----AKKAGAQR---------KEEEAERKQLQAKLQQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757
Cdd:pfam07888 183 TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLT---QKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEM-----------ENQTLQKNLEELKISSKRL-EQLEKENKSLEQETS 825
Cdd:pfam07888 260 LSSMAAQRDRTQAELHQARLQAAQLTLQLADASLalregrarwaqERETLQQSAEADKDRIEKLsAELQRLEERLQEERM 339
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 1465187875 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Cdd:pfam07888 340 EREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEK 387
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
688-1219 |
1.81e-09 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 62.75 E-value: 1.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 688 QLESLEKENSQLDEENLelrrnVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKasfkktERLEvSYQGLDIENQR 767
Cdd:PRK02224 188 SLDQLKAQIEEKEEKDL-----HERLNGLESELAELDEEIERYEEQREQARETRDEAD------EVLE-EHEERREELET 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 768 LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL------------------KISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELeeerddllaeaglddadaEAVEARREELEDRDEELRDRLEECRV 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 830 DKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEscvRLKELEKENKELVKR---ATIDIKTLVT 906
Cdd:PRK02224 336 AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRRE---EIEELEEEIEELRERfgdAPVDLGNAED 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD------EQSTDDS-RYKLLESKLE--STLKKSLEIKEEKIA 977
Cdd:PRK02224 413 FLEELREERDELREREAELEATLRTARERVEEAEALLEAgkcpecGQPVEGSpHVETIEEDRErvEELEAELEDLEEEVE 492
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 978 ALEARLEESTNYnQQLRQELKTVKKNYEALKQR--QDEERMVQSSPPISG---EDNKWERESQETTRELLKVKDRLIEVE 1052
Cdd:PRK02224 493 EVEERLERAEDL-VEAEDRIERLEERREDLEELiaERRETIEEKRERAEElreRAAELEAEAEEKREAAAEAEEEAEEAR 571
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1053 RNNATLQAEKQALKTQLKQLETQnNNLQAQILALQRQTVSLQEQNTTLQTQNA------------KLQVENSTLNSQSTS 1120
Cdd:PRK02224 572 EEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLREKREALAELNDerrerlaekrerKRELEAEFDEARIEE 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1121 LMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQaseyESLISKHGTLKSAHKNLEvehrDLED 1200
Cdd:PRK02224 651 AREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERR----EALENRVEALEALYDEAE----ELES 722
|
570 580
....*....|....*....|..
gi 1465187875 1201 RYNQL---LKQKgQLEDLEKML 1219
Cdd:PRK02224 723 MYGDLraeLRQR-NVETLERML 743
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
594-837 |
1.83e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 61.70 E-value: 1.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 594 ESIKETSSKLSKIEFEKRQIKKELEHYKEKgerAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENR 673
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKE---EKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 674 KLKKTLDSFKN-LTFQLESLEKENSQldeENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKglellkasfkKTE 752
Cdd:COG4942 94 ELRAELEAQKEeLAELLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRA----------DLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 753 RLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKK 832
Cdd:COG4942 161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELA---AELAELQQEAEELEALIARLEAEAA 237
|
....*
gi 1465187875 833 QLEKE 837
Cdd:COG4942 238 AAAER 242
|
|
| HkD_Hook1 |
cd22225 |
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a ... |
18-163 |
2.44e-09 |
|
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a microtubule-binding protein required for spermatid differentiation. It is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411796 Cd Length: 150 Bit Score: 57.94 E-value: 2.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 18 LVTWVKTFGPLAAGNGTNldeyvALVDGVFLNQVMLQINPKLESQ----RVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:cd22225 5 LIIWLQTFNTAAPCQTVQ-----DLTSGVAMAQVLHQIDSSWFDEswlsRIKEDVGDNWRIKMSNLKKILQGIVDYYHEF 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 94 L-QQLIMMSLPNVliigkNPFSEQGTE-EVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22225 80 LdQQISEFLLPDL-----NRIAEHSDPvELGRLLQLILGCAVNCEKKQEHIQNIMTLEESVQHVVMTAIQEL 146
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
262-1251 |
2.74e-09 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 62.50 E-value: 2.74e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSdarsarmyrdeldalrEKAVRVDKLESEVSRYKERlhdiEF 341
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCE----------------EKNALQEQLQAETELCAEA----EE 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 342 YKARVEELKednQVLLETKTMLEDQLEGTRARSDKLHELEKEnlqLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ 421
Cdd:pfam01576 62 MRARLAARK---QELEEILHELESRLEEEEERSQQLQNEKKK---MQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKK 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 422 SMDESLHLGWELEQISRTselseapQKSLGHEVNELTSSrLLKLEMENQSLTKTVEELRTTVDSVEGnasKILKMEKENQ 501
Cdd:pfam01576 136 LEEDILLLEDQNSKLSKE-------RKLLEERISEFTSN-LAEEEEKAKSLSKLKNKHEAMISDLEE---RLKKEEKGRQ 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 502 RLSKKVEILENEIVQEKQSLQNCQNLSKDLmkeKAQLEKTIETLRENSERqikiLEQENEHLNQTVSSLRQrsqisAEAR 581
Cdd:pfam01576 205 ELEKAKRKLEGESTDLQEQIAELQAQIAEL---RAQLAKKEEELQAALAR----LEEETAQKNNALKKIRE-----LEAQ 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 582 VKDiekenkiLHESIKETSSKLSKIEFEKRQIKKELEHYKEkgeraeELENELHHLEKENELLQKK---ITNLKitceki 658
Cdd:pfam01576 273 ISE-------LQEDLESERAARNKAEKQRRDLGEELEALKT------ELEDTLDTTAAQQELRSKReqeVTELK------ 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 659 EALEQENSELERENRKL-KKTLDSFKNLTFQLE-------SLEKENSQLDEENLELRRNVESLKCASMkmaqlqlenkEL 730
Cdd:pfam01576 334 KALEEETRSHEAQLQEMrQKHTQALEELTEQLEqakrnkaNLEKAKQALESENAELQAELRTLQQAKQ----------DS 403
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 731 ESEKEQLKKGLELLKASFKKTER----LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEE---- 802
Cdd:pfam01576 404 EHKRKKLEGQLQELQARLSESERqraeLAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEetrq 483
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 803 -LKISSkRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGI----YK 877
Cdd:pfam01576 484 kLNLST-RLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEAltqqLE 562
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 878 ESCVRLKELEKENKELVKRAtidiktlvtlrEDLVSEKLKTQQMNNDLEKLTHELEKiglnkerlLHDEQSTDDSRYKLL 957
Cdd:pfam01576 563 EKAAAYDKLEKTKNRLQQEL-----------DDLLVDLDHQRQLVSNLEKKQKKFDQ--------MLAEEKAISARYAEE 623
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 958 ESKLESTLKKsleiKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEerMVQSSPPISGEDNKWERESQET 1037
Cdd:pfam01576 624 RDRAEAEARE----KETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDD--VGKNVHELERSKRALEQQVEEM 697
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1038 TRELLKVKDRLIEVERNNATLQAEKQALKTQL--------KQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV 1109
Cdd:pfam01576 698 KTQLEELEDELQATEDAKLRLEVNMQALKAQFerdlqardEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEL 777
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1110 ENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHK 1189
Cdd:pfam01576 778 DLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARR 857
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1465187875 1190 NLEVEHRDLEDRYNQLLKQKGQLED----LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLN 1251
Cdd:pfam01576 858 QAQQERDELADEIASGASGKSALQDekrrLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLT 923
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
264-782 |
4.01e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 61.68 E-value: 4.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 264 RQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDarSARMYRDELDALREKAVRVDKLESEVSRYKERLHD-IEFY 342
Cdd:pfam05557 1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASA--LKRQLDRESDRNQELQKRIRLLEKREAEAEEALREqAELN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHEL----EKENLQLKAKLHDMEMER---DMDRKKIEELMEENMTL 415
Cdd:pfam05557 79 RLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELrrqiQRAELELQSTNSELEELQerlDLLKAKASEAEQLRQNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 416 EMAQKQSMDESLH---LGWELEQISRTSELSEAPQKSLGhEVNELTS---------SRLLKLEMENQSLTKTVEELRTTV 483
Cdd:pfam05557 159 EKQQSSLAEAEQRikeLEFEIQSQEQDSEIVKNSKSELA-RIPELEKelerlrehnKHLNENIENKLLLKEEVEDLKRKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 484 DSVEGNASKILKMEKENQRLSKKV-----------------EILENEIVQEKQ--------------SLQNCQNLSKDLM 532
Cdd:pfam05557 238 EREEKYREEAATLELEKEKLEQELqswvklaqdtglnlrspEDLSRRIEQLQQreivlkeenssltsSARQLEKARRELE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 533 KEKAQLEKTIETL---RENSERQIKILEQENEHLNQTVSSLRQ-----RSQISAEARVKDIEKENKILHESIKETSSKLS 604
Cdd:pfam05557 318 QELAQYLKKIEDLnkkLKRHKALVRRLQRRVLLLTKERDGYRAilesyDKELTMSNYSPQLLERIEEAEDMTQKMQAHNE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 605 KIEFEKRQIKKELEHYKekgERAEELENELHHLEKENELLQKKITNLKITC--EKIEALEQENSELERENRKLKKtldsf 682
Cdd:pfam05557 398 EMEAQLSVAEEELGGYK---QQAQTLERELQALRQQESLADPSYSKEEVDSlrRKLETLELERQRLREQKNELEM----- 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 683 knltfqleSLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLD 762
Cdd:pfam05557 470 --------ELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMN 541
|
570 580
....*....|....*....|.
gi 1465187875 763 I-ENQRLQKTLENSNKKIQQL 782
Cdd:pfam05557 542 FkEVLDLRKELESAELKNQRL 562
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
611-1341 |
4.02e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 61.85 E-value: 4.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 611 RQIKKELEHYKEKGERAEELENELHHLEKENELlqkkitnlkitCEKIEALEQENSELERenrkLKKTLDSFKNLTfQLE 690
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLEPIREL-----------AERYAAARERLAELEY----LRAALRLWFAQR-RLE 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 691 SLEKEnsqLDEENLELRRNVEslkcasmKMAQLQLENKELESEKEQLKKglELLKASFKKTERLEVsyqgldiENQRLQK 770
Cdd:COG4913 292 LLEAE---LEELRAELARLEA-------ELERLEARLDALREELDELEA--QIRGNGGDRLEQLER-------EIERLER 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 771 TLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK-RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQqaEIKD 849
Cdd:COG4913 353 ELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAaLLEALEEELEALEEALAEAEAALRDLRRELRELEA--EIAS 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 850 ttLEENNVKI-GNLEKENKTLSKEIGIYKESCVRLKEL-EKENKELVKRATIDiKTLVTLRED-LVSEKlktqqmnnDLE 926
Cdd:COG4913 431 --LERRKSNIpARLLALRDALAEALGLDEAELPFVGELiEVRPEEERWRGAIE-RVLGGFALTlLVPPE--------HYA 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 927 KLTHELEKIGLnKERLLHDEQSTDDSRYKLLESKLESTLKKsLEIKEEKIAA-LEARLEESTNY-----NQQLRQELK-- 998
Cdd:COG4913 500 AALRWVNRLHL-RGRLVYERVRTGLPDPERPRLDPDSLAGK-LDFKPHPFRAwLEAELGRRFDYvcvdsPEELRRHPRai 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 999 ----TVKKNYEAL-KQRQDEERmvqsSPPISGEDNkweresqettRELLKVKDRLIevernnATLQAEKQALKTQLKQLE 1073
Cdd:COG4913 578 tragQVKGNGTRHeKDDRRRIR----SRYVLGFDN----------RAKLAALEAEL------AELEEELAEAEERLEALE 637
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1074 TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAklqvenstlnsqstslmnqnaqllIQQssLENENESVIKEREDLKSLY 1153
Cdd:COG4913 638 AELDALQERREALQRLAEYSWDEIDVASAERE------------------------IAE--LEAELERLDASSDDLAALE 691
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1154 DSLikdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL--LKQKGQLEDLEKMLKVEQEKmllenK 1231
Cdd:COG4913 692 EQL----EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAedLARLELRALLEERFAAALGD-----A 762
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1232 NHETVAAEY-KKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKE----QYQQlDITSTKL 1306
Cdd:COG4913 763 VERELRENLeERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEdglpEYEE-RFKELLN 841
|
730 740 750
....*....|....*....|....*....|....*
gi 1465187875 1307 NNQCELLSQLKGNLEEENRHLLDQIQTLmlqNRTL 1341
Cdd:COG4913 842 ENSIEFVADLLSKLRRAIREIKERIDPL---NDSL 873
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
577-816 |
5.19e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 60.55 E-value: 5.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELehykekgeraEELENELHHLEKENELLQKKITNLKitcE 656
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL----------AALERRIAALARRIRALEQELAALE---A 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 657 KIEALEQENSELERENRKLKKTLDSfknltfQLESLEKENSQldeENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Cdd:COG4942 84 ELAELEKEIAELRAELEAQKEELAE------LLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 737 LKKGLELLKAS----FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQ 812
Cdd:COG4942 155 LRADLAELAALraelEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
|
....
gi 1465187875 813 LEKE 816
Cdd:COG4942 235 EAAA 238
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
495-1418 |
1.52e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 60.06 E-value: 1.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQL--EKTIETLRENSERQIKILEQENEHLNQTVSSLrq 572
Cdd:TIGR00606 190 TLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLesSREIVKSYENELDPLKNRLKEIEHNLSKIMKL-- 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 573 rsqisaEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY-----KEKGERAEELENELHHLEKENELLQKK 647
Cdd:TIGR00606 268 ------DNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHNhqrtvREKERELVDCQRELEKLNKERRLLNQE 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 648 ITNLKITCEKIEALEQENSE------LERENRKLKKTLDSFKNLTFqLESLEKENSQLDEENLELRRNVESLKCASM--K 719
Cdd:TIGR00606 342 KTELLVEQGRLQLQADRHQEhirardSLIQSLATRLELDGFERGPF-SERQIKNFHTLVIERQEDEAKTAAQLCADLqsK 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 720 MAQLQLENKELESEKEQLKKGLELlkasfkKTERLEvsyqgldienqRLQKTLENSNKKIQQLESELQDLEMENQTLQKN 799
Cdd:TIGR00606 421 ERLKQEQADEIRDEKKGLGRTIEL------KKEILE-----------KKQEELKFVIKELQQLEGSSDRILELDQELRKA 483
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 800 LEELKISSKR--LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL---EENNVKIGNLEKENKTLSKEIG 874
Cdd:TIGR00606 484 ERELSKAEKNslTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltKDKMDKDEQIRKIKSRHSDELT 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 875 IYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIglnkERLLHDEQSTDDsry 954
Cdd:TIGR00606 564 SLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY----EDKLFDVCGSQD--- 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 955 klLESKLEStLKKSLEIKEEKIAALEARleesTNYNQQLRQELKTVKKNYEALKQR--QDEERMVQSSPPISGEDNKWER 1032
Cdd:TIGR00606 637 --EESDLER-LKEEIEKSSKQRAMLAGA----TAVYSQFITQLTDENQSCCPVCQRvfQTEAELQEFISDLQSKLRLAPD 709
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1033 ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIlalQRQTVSLQEQNTTLQTQNAKLQVENS 1112
Cdd:TIGR00606 710 KLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDI---QRLKNDIEEQETLLGTIMPEEESAKV 786
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1113 TLNS---------QSTSLMNQNAQLL--IQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKH 1181
Cdd:TIGR00606 787 CLTDvtimerfqmELKDVERKIAQQAakLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKT 866
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1182 GTLKSAHKNLevehrdledryNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHEtvaaeykklcgendrlnhtySQLLKET 1261
Cdd:TIGR00606 867 NELKSEKLQI-----------GTNLQRRQQFEEQLVELSTEVQSLIREIKDAK--------------------EQDSPLE 915
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1262 EVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEllsqlkgnlEEENRHLLDQiqtlmlqnrtl 1341
Cdd:TIGR00606 916 TFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQ---------DGKDDYLKQK----------- 975
|
890 900 910 920 930 940 950
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1465187875 1342 leqnmeskdlfHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSL 1418
Cdd:TIGR00606 976 -----------ETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHL 1041
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
883-1347 |
1.75e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 59.40 E-value: 1.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 883 LKELEKENKELVK----RATIDIKTLVTLREDLVSEKLKTQQmnndLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLE 958
Cdd:COG4717 48 LERLEKEADELFKpqgrKPELNLKELKELEEELKEAEEKEEE----YAELQEELEELEEELEELEAELEELREELEKLEK 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 959 SKLESTLKKSLEIKEEKIAALEARLEEstnynqqLRQELKTVKKNYEALKQRQDEERMVQSSppisgEDNKWERESQETT 1038
Cdd:COG4717 124 LLQLLPLYQELEALEAELAELPERLEE-------LEERLEELRELEEELEELEAELAELQEE-----LEELLEQLSLATE 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1039 RELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTvSLQEQNTTLQTQNAKLQVENSTLNSQS 1118
Cdd:COG4717 192 EELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE-RLKEARLLLLIAAALLALLGLGGSLLS 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1119 TSLMNQNAQLLIQQ------SSLENENESVIKEREDLKSLYD-------SLIKDHEKLELLHERQASEYESLISKHGTLK 1185
Cdd:COG4717 271 LILTIAGVLFLVLGllallfLLLAREKASLGKEAEELQALPAleeleeeELEELLAALGLPPDLSPEELLELLDRIEELQ 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1186 SAHKNLEVEHRDLedrynQLLKQKGQLEDLEKMLKVEQEKMLLEnknHETVAAEYKKLCGENDRLNHTYSQLLKETEVL- 1264
Cdd:COG4717 351 ELLREAEELEEEL-----QLEELEQEIAALLAEAGVEDEEELRA---ALEQAEEYQELKEELEELEEQLEELLGELEELl 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1265 -QTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCEL--LSQLKGNLEEENRHLLDQIQTLMLQnRTL 1341
Cdd:COG4717 423 eALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGELaeLLQELEELKAELRELAEEWAALKLA-LEL 501
|
....*.
gi 1465187875 1342 LEQNME 1347
Cdd:COG4717 502 LEEARE 507
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
991-1208 |
2.32e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.24 E-value: 2.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 991 QQLRQELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKtqlK 1070
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKA--LLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---A 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1071 QLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST--LNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1148
Cdd:COG4942 98 ELEAQKEELAELLRALYRL--GRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1149 LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQ 1208
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
725-1317 |
4.01e-08 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 58.37 E-value: 4.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK 804
Cdd:PRK01156 159 LEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLK 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEScvrLK 884
Cdd:PRK01156 239 SALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQI---LS 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 885 ELEKEnkelVKRATIDIKTLVTLREDLvSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSR--YKLLESKLE 962
Cdd:PRK01156 316 NIDAE----INKYHAIIKKLSVLQKDY-NDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIeeYSKNIERMS 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 963 STLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMV------QSSPPISGE---DNKWERE 1033
Cdd:PRK01156 391 AFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNmemlngQSVCPVCGTtlgEEKSNHI 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1034 SQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNN-----------LQAQILALQRQTVSLQEQNTTL-Q 1101
Cdd:PRK01156 471 INHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINksineynkiesARADLEDIKIKINELKDKHDKYeE 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1102 TQNAKLQVENSTLNSQSTSLMNQNAQLliqqSSLENENesVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKh 1181
Cdd:PRK01156 551 IKNRYKSLKLEDLDSKRTSWLNALAVI----SLIDIET--NRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIRE- 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1182 gtlksahknLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEkmllenknhetvaaEYKKLCGENDRLNHTYSQLLKet 1261
Cdd:PRK01156 624 ---------IENEANNLNNKYNEIQENKILIEKLRGKIDNYKK--------------QIAEIDSIIPDLKEITSRIND-- 678
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 1465187875 1262 evLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLK 1317
Cdd:PRK01156 679 --IEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIK 732
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
241-570 |
4.13e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.54 E-value: 4.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 241 KRTESRQH---LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllsdarsarmYRDELDALRE 317
Cdd:TIGR02169 696 ELRRIENRldeLSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN----------VKSELKELEA 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 318 kavRVDKLESEVSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE----LEKENLQLKAKL 391
Cdd:TIGR02169 766 ---RIEELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLekeyLEKEIQELQEQR 842
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 392 HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Cdd:TIGR02169 843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 472 LTK---------TVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE---NEIVQEKQSLQNCQNLSKD----LMKEK 535
Cdd:TIGR02169 923 KAKlealeeelsEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEpvnMLAIQEYEEVLKRLDELKEkrakLEEER 1002
|
330 340 350
....*....|....*....|....*....|....*..
gi 1465187875 536 AQLEKTIETLrENSERQI--KILEQENEHLNQTVSSL 570
Cdd:TIGR02169 1003 KAILERIEEY-EKKKREVfmEAFEAINENFNEIFAEL 1038
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
770-1202 |
4.17e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.24 E-value: 4.17e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 770 KTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE--KENKRLRQQAEI 847
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 848 KDT---TLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKElvKRATIDIKTLVTLREDLVSEKLKTQQMNND 924
Cdd:COG4717 144 LPErleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 925 LEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLES--TLKKSLEIKEEKIAALEARLEE--STNYNQQLRQELKTV 1000
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEARLLLLIAAALLAllGLGGSLLSLILTIAGVLFLVLGllALLFLLLAREKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1001 KKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERnnatlQAEKQALKTQLKQLETQNNNLQ 1080
Cdd:COG4717 302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR-----EAEELEEELQLEELEQEIAALL 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1081 A-----------QILALQRQTVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERE 1147
Cdd:COG4717 377 AeagvedeeelrAALEQAEEYQELKEELEELEEQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELA 456
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 1465187875 1148 DLKSLYDSLIKDHEKLELLHERQ--ASEYESLISKHGTLKSAHKNLEVEHRDLEDRY 1202
Cdd:COG4717 457 ELEAELEQLEEDGELAELLQELEelKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
796-1158 |
4.32e-08 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 58.38 E-value: 4.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 796 LQKNLEELKissKRlEQLEKENKSLEQ---ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Cdd:PRK11281 41 VQAQLDALN---KQ-KLLEAEDKLVQQdleQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 873 IgIYKEScvrLKELEKE-NKELVKRATIDiKTLVTLREDLVSEK--------------LKTQQMNNDL------EKLTHE 931
Cdd:PRK11281 117 T-LSTLS---LRQLESRlAQTLDQLQNAQ-NDLAEYNSQLVSLQtqperaqaalyansQRLQQIRNLLkggkvgGKALRP 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 932 LEKIGLNKERLLHDEQStdDSRYKLLE--SKLESTLKKSLEIKEEKIAALEAR---LEESTNyNQQLRQELKTVKknyEA 1006
Cdd:PRK11281 192 SQRVLLQAEQALLNAQN--DLQRKSLEgnTQLQDLLQKQRDYLTARIQRLEHQlqlLQEAIN-SKRLTLSEKTVQ---EA 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1007 lkQRQDEERMVQSSPPISGEdnkweresQETTRELlkvKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL 1086
Cdd:PRK11281 266 --QSQDEAARIQANPLVAQE--------LEINLQL---SQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVL 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1087 ------------QRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA---QLLIQQSSLENENE-----SVIKER 1146
Cdd:PRK11281 333 kgslllsrilyqQQQALPSADLIEGLADRIADLRLEQFEINQQRDALFQPDAyidKLEAGHKSEVTDEVrdallQLLDER 412
|
410
....*....|..
gi 1465187875 1147 EDlksLYDSLIK 1158
Cdd:PRK11281 413 RE---LLDQLNK 421
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
575-831 |
6.24e-08 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 57.72 E-value: 6.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 575 QISAEARVKDIE---------KENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENElhhlekENELLQ 645
Cdd:PHA02562 146 QLSAPARRKLVEdlldisvlsEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGE------NIARKQ 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 646 KKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCasmkMAQLQ 724
Cdd:PHA02562 220 NKYDELVEEAKTIKAeIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTC----TQQIS 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 725 LENKELESEKEQLK---KGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQknlE 801
Cdd:PHA02562 296 EGPDRITKIKDKLKelqHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQ---A 372
|
250 260 270
....*....|....*....|....*....|
gi 1465187875 802 ELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:PHA02562 373 EFVDNAEELAKLQDELDKIVKTKSELVKEK 402
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
261-878 |
1.50e-07 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 57.01 E-value: 1.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENmnllsdarsarmyrDELDALREKAVRVDKLESEVSRYKErlhdie 340
Cdd:COG5022 857 AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDV--------------KSISSLKLVNLELESEIIELKKSLS------ 916
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 341 fykarvEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKenLQLKAKLHDMEmerdmdrKKIEELMEEnmtLEMAQK 420
Cdd:COG5022 917 ------SDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVK--LPELNKLHEVE-------SKLKETSEE---YEDLLK 978
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 421 QSmdeslhlgweleqisrtselseapqkslghevnELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKEN 500
Cdd:COG5022 979 KS---------------------------------TILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEV 1025
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 501 QRLSKKVEILeNEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRenserqikiLEQENEHLNQTVSSLRQRSQIsaea 580
Cdd:COG5022 1026 AELQSASKII-SSESTELSILKPLQKLKGLLLLENNQLQARYKALK---------LRRENSLLDDKQLYQLESTEN---- 1091
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 581 rvkdieKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitCEKIEA 660
Cdd:COG5022 1092 ------LLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELD--GLFWEA 1163
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 661 LEQENSELERENRKLKKTLdsfknltFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG 740
Cdd:COG5022 1164 NLEALPSPPPFAALSEKRL-------YQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVPTEY 1236
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 741 LELLKAS-----FKKTERLEVSYQGLDIENQrLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEK 815
Cdd:COG5022 1237 STSLKGFnnlnkKFDTPASMSNEKLLSLLNS-IDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKSATE 1315
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 816 ENKSLEQE------------TSQLEKDK---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE 878
Cdd:COG5022 1316 VNYNSEELddwcrefeisdvDEELEELIqavKVLQLLKDDLNKLDELLDACYSLNPAEIQNLKSRYDPADKENNLPKE 1393
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
252-822 |
1.59e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.85 E-value: 1.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllSDARSARMYRDELDALREkavRVDKLESEVSR 331
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLER---ELEERERRRAR 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 332 YKERLHDIEFykarveELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLhdmemerdmdRKKIEELMEE 411
Cdd:COG4913 364 LEALLAALGL------PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL----------RRELRELEAE 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 412 NMTLEmAQKQSMDESLHlgwEL-EQISRTSELSEAPQKSLGH--EVNELTSS------RLLKlemeNQSLTKTVEE---- 478
Cdd:COG4913 428 IASLE-RRKSNIPARLL---ALrDALAEALGLDEAELPFVGEliEVRPEEERwrgaieRVLG----GFALTLLVPPehya 499
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 479 ----------LRTTVDS--VEGNASKILKMEKENQRLSKKVEILENEIvqekqslqncQNLSKDLMKEKAQLEK--TIET 544
Cdd:COG4913 500 aalrwvnrlhLRGRLVYerVRTGLPDPERPRLDPDSLAGKLDFKPHPF----------RAWLEAELGRRFDYVCvdSPEE 569
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 545 LRENS-----ERQIKILEQENEHlnQTVSSLRQRSQI--SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKEL 617
Cdd:COG4913 570 LRRHPraitrAGQVKGNGTRHEK--DDRRRIRSRYVLgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERR 647
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 618 EHY-------------KEKGERAEELENELHHLEKEN---ELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDS 681
Cdd:COG4913 648 EALqrlaeyswdeidvASAEREIAELEAELERLDASSddlAALEEQLEELE---AELEELEEELDELKGEIGRLEKELEQ 724
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 682 F----KNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM-AQLQLENKELESEKEQLKKGLELLKASFKKTERLEV 756
Cdd:COG4913 725 AeeelDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELrENLEERIDALRARLNRAEEELERAMRAFNREWPAET 804
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1465187875 757 SYQGLDIEN----QRLQKTLENSN-----KKIQQL--ESELQDLEMENQTLQKNLEELKisskrlEQLEKENKSLEQ 822
Cdd:COG4913 805 ADLDADLESlpeyLALLDRLEEDGlpeyeERFKELlnENSIEFVADLLSKLRRAIREIK------ERIDPLNDSLKR 875
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
867-1190 |
1.74e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.48 E-value: 1.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 867 KTLSKEIGIYkESCVRLKELEKENKELvKRATIDIKTLVTLREDLVSEKlktQQMNNDLEKLTHELEKIGLNKERLLHDE 946
Cdd:COG1196 216 RELKEELKEL-EAELLLLKLRELEAEL-EELEAELEELEAELEELEAEL---AELEAELEELRLELEELELELEEAQAEE 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 947 QstddsrykLLESKLEsTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSppisge 1026
Cdd:COG1196 291 Y--------ELLAELA-RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE------ 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1027 dnKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLkQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAK 1106
Cdd:COG1196 356 --AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAA-ELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1107 LQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKS 1186
Cdd:COG1196 433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512
|
....
gi 1465187875 1187 AHKN 1190
Cdd:COG1196 513 ALLL 516
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
508-872 |
1.90e-07 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 55.46 E-value: 1.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 508 EILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK---ILEQE---NEHLNQTVSSLRQRSQiSAEAR 581
Cdd:pfam19220 6 ELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLEleaLLAQEraaYGKLRRELAGLTRRLS-AAEGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 582 VKDIEKENKILHESIKETSSKLSKIEFEKRQ-------IKKELEHykeKGERAEELENELHHLEKENELLQKKITNLKit 654
Cdd:pfam19220 85 LEELVARLAKLEAALREAEAAKEELRIELRDktaqaeaLERQLAA---ETEQNRALEEENKALREEAQAAEKALQRAE-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 655 cEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESlKCASMK------MAQLQLENK 728
Cdd:pfam19220 160 -GELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEG-QLAAEQaereraEAQLEEAVE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 729 ELESEKEQLKKGLELLKASFKKTERLevsyqgldienqrlqktlensnkkIQQLESELQDLEMENQTLQKNLEELKIS-- 806
Cdd:pfam19220 238 AHRAERASLRMKLEALTARAAATEQL------------------------LAEARNQLRDRDEAIRAAERRLKEASIErd 293
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 807 --SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Cdd:pfam19220 294 tlERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKR 361
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
917-1148 |
2.09e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 55.16 E-value: 2.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRyKLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 996
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL-AALERRI-AALARRIRALEQELAALEAELAELEKEIAELRAE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 997 LKTVKKNYEALKQRQdeERMVQSSPP---ISGEDnkweresqettreLLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Cdd:COG4942 99 LEAQKEELAELLRAL--YRLGRQPPLallLSPED-------------FLDAVRRLQYLKYLAPARREQAEELRADLAELA 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1465187875 1074 TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1148
Cdd:COG4942 164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
345-652 |
2.37e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 55.90 E-value: 2.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 345 RVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdMEMERDMDRKKIEELMEENMTLEMAQkqsmd 424
Cdd:pfam17380 300 RLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMA-----MERERELERIRQEERKRELERIRQEE----- 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 425 eslhLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLK-LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRl 503
Cdd:pfam17380 370 ----IAMEISRMRELERLQMERQQKNERVRQELEAARKVKiLEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEER- 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 504 SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHlnqtvsslRQRSQISAEARVK 583
Cdd:pfam17380 445 AREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE--------RKQAMIEEERKRK 516
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 584 DIEKENKILHESIKETSSKlsKIEFEKRQIKKELEHYK---EKGERAEELENELHHLEKENELLQKKITNLK 652
Cdd:pfam17380 517 LLEKEMEERQKAIYEEERR--REAEEERRKQQEMEERRriqEQMRKATEERSRLEAMEREREMMRQIVESEK 586
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
573-861 |
2.59e-07 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 56.07 E-value: 2.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 573 RSQISAEARVKDIEKENKILHESIKETSSKLSKIEfekrQIKKELehykekgeraEELENELHHLEKENELLQKKITNLK 652
Cdd:PRK11281 42 QAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKID----RQKEET----------EQLKQQLAQAPAKLRQAQAELEALK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 653 ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLekeNSQLDEENLELRRNVESLKCASMKMAQLqleNKELES 732
Cdd:PRK11281 108 DDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEY---NSQLVSLQTQPERAQAALYANSQRLQQI---RNLLKG 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 733 EKEqlkkGLELLKASFKktERLEVSYQGLDIENQRLQKTLENsNKKIQQLESELQDLEMENQT-LQKNLEELK--ISSKR 809
Cdd:PRK11281 182 GKV----GGKALRPSQR--VLLQAEQALLNAQNDLQRKSLEG-NTQLQDLLQKQRDYLTARIQrLEHQLQLLQeaINSKR 254
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 810 LEQLEKENKSLE--QETSQLEKD---KKQLEKeNKRLRQ---QAEIKDTTLEENNVKIGN 861
Cdd:PRK11281 255 LTLSEKTVQEAQsqDEAARIQANplvAQELEI-NLQLSQrllKATEKLNTLTQQNLRVKN 313
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
726-893 |
2.74e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.77 E-value: 2.74e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 726 ENKELESEKEQLKKGLELLKASFKKTERLEVSYQG----LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlaaLERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 802 ELK-----------------------------ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:COG4942 101 AQKeelaellralyrlgrqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1465187875 853 EENNVKIGNLEKE----NKTLSKEIGIYKESCVRLKELEKENKEL 893
Cdd:COG4942 181 AELEEERAALEALkaerQKLLARLEKELAELAAELAELQQEAEEL 225
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
287-888 |
4.15e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 55.29 E-value: 4.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 287 ELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYkerlhdiefykarVEELKEDNQVLLETKTMLEDQ 366
Cdd:PRK01156 150 QRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSS-------------NLELENIKKQIADDEKSHSIT 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 367 LEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQisRTSELSEAP 446
Cdd:PRK01156 217 LKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYK-----ELEE--RHMKIINDP 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 447 QKSLGHEVNELtssrlLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKE-NQRLSKKVEIleNEIVQEKQSLQNCQ 525
Cdd:PRK01156 290 VYKNRNYINDY-----FKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDyNDYIKKKSRY--DDLNNQILELEGYE 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 526 NLSKDLMKEKAQLEKTIETLRENSERqikileqenehLNQTVSSLRQRSQISAEARVKDIEKENKilheSIKETSSKLSK 605
Cdd:PRK01156 363 MDYNSYLKSIESLKKKIEEYSKNIER-----------MSAFISEILKIQEIDPDAIKKELNEINV----KLQDISSKVSS 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 606 IEFEKRQIKKELEHYKEK-----------------------------GERAEELENELHHLEKENELLQKKITNLK---- 652
Cdd:PRK01156 428 LNQRIRALRENLDELSRNmemlngqsvcpvcgttlgeeksnhiinhyNEKKSRLEEKIREIEIEVKDIDEKIVDLKkrke 507
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 653 -ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE-LRRNVESLKCASMKMAQLQLENkeL 730
Cdd:PRK01156 508 yLESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEdLDSKRTSWLNALAVISLIDIET--N 585
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 731 ESEKEQLKKglellkasfkKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRL 810
Cdd:PRK01156 586 RSRSNEIKK----------QLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNY 655
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Cdd:PRK01156 656 KKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIKK 733
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
762-897 |
4.25e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 54.86 E-value: 4.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 762 DIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQET-SQLEKDKK--QLEKEN 838
Cdd:COG2433 398 EREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKD---ERIERLERELSEARSEErREIRKDREisRLDREI 474
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1465187875 839 KRLRQQAEIKDTTLEENNVKignLEKENKTLSKEIgiyKESCVRLKELEKENKELVKRA 897
Cdd:COG2433 475 ERLERELEEERERIEELKRK---LERLKELWKLEH---SGELVPVKVVEKFTKEAIRRL 527
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
559-914 |
4.45e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 55.13 E-value: 4.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 559 ENEHLNQTVSSLRQRSQISAEarvKDIEKENKILHESIKETSSKLSKiEFEKRQIKKELEH------------YKEKGER 626
Cdd:pfam17380 267 ENEFLNQLLHIVQHQKAVSER---QQQEKFEKMEQERLRQEKEEKAR-EVERRRKLEEAEKarqaemdrqaaiYAEQERM 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 627 AEELENELHHL---EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703
Cdd:pfam17380 343 AMERERELERIrqeERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 704 LELRRNVESLKcasmkmaqlQLENKELESEKEQlkkglELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLE 783
Cdd:pfam17380 423 EQIRAEQEEAR---------QREVRRLEEERAR-----EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKR 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 784 SElqdlEMENQTLQKNLEElkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE 863
Cdd:pfam17380 489 AE----EQRRKILEKELEE-----RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMR 559
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 1465187875 864 KENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSE 914
Cdd:pfam17380 560 KATEERSRLEAMEREREMMRQIVESEKARAEYEATTPITTIKPIYRPRISE 610
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
775-1030 |
5.82e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.00 E-value: 5.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 775 SNKKIQQLESELQDLEmenqtlqknlEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Cdd:COG4942 18 QADAAAEAEAELEQLQ----------QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 855 NNVKIGNLEKENKTLSKEigiYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLvseKLKTQQMNNDLEKLTHELEK 934
Cdd:COG4942 88 LEKEIAELRAELEAQKEE---LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL---KYLAPARREQAEELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 935 IGLNKERLLHDEQSTDDSRYKLLESKLEstLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEE 1014
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAA--LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
|
250
....*....|....*.
gi 1465187875 1015 RMVQSSPPISGEDNKW 1030
Cdd:COG4942 240 AERTPAAGFAALKGKL 255
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
243-673 |
6.54e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.39 E-value: 6.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 243 TESRQHLSVELADAKAKIRRLRQELE--EKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsARMYRDELDALREKAV 320
Cdd:COG4717 94 QEELEELEEELEELEAELEELREELEklEKLLQLLPLYQELEALEAELAELPER----------LEELEERLEELRELEE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 321 RVDKLESEVSRYKERLHDIEFY-----KARVEELKEDNQVLLETKTMLEDQLEGTRArsdklhelEKENLQLKAKLHDME 395
Cdd:COG4717 164 ELEELEAELAELQEELEELLEQlslatEEELQDLAEELEELQQRLAELEEELEEAQE--------ELEELEEELEQLENE 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 396 MERDMDRKKIEELMEENM------TLEMAQKQSMDESLHLG----WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKl 465
Cdd:COG4717 236 LEAAALEERLKEARLLLLiaaallALLGLGGSLLSLILTIAgvlfLVLGLLALLFLLLAREKASLGKEAEELQALPALE- 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 466 EMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIvQEKQSLQNCQNLskdLMKEKAQLEKTIETL 545
Cdd:COG4717 315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL-QLEELEQEIAAL---LAEAGVEDEEELRAA 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 546 RENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYkEKGE 625
Cdd:COG4717 391 LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL-EEDG 469
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 1465187875 626 RAEELENELHHLEKENELLQKKITNLKITcekIEALEQENSELERENR 673
Cdd:COG4717 470 ELAELLQELEELKAELRELAEEWAALKLA---LELLEEAREEYREERL 514
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
183-677 |
7.62e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.59 E-value: 7.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 183 QEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELAdAKAKIRR 262
Cdd:TIGR00618 385 QQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKL-EKIHLQE 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 263 LRQELEEKTEQLLD----CKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAV---RVDKLESEVSRYKER 335
Cdd:TIGR00618 464 SAQSLKEREQQLQTkeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPltrRMQRGEQTYAQLETS 543
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 336 LHDIE-----------FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLhdMEMERDMDRKK 404
Cdd:TIGR00618 544 EEDVYhqltserkqraSLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDML--ACEQHALLRKL 621
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 405 IEELMEENMTLEMAQKQSMDeslhlgwELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 484
Cdd:TIGR00618 622 QPEQDLQDVRLHLQQCSQEL-------ALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTY 694
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 485 SVEGNASKILKMEKENQRLsKKVEILENEIVQEKQSLQncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Cdd:TIGR00618 695 WKEMLAQCQTLLRELETHI-EEYDREFNEIENASSSLG------SDLAAREDALNQSLKELMHQARTVLKARTEAHFNNN 767
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 565 QTVSSLRQRSQISAEArVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKgeRAEELENELHHLEKENELL 644
Cdd:TIGR00618 768 EEVTAALQTGAELSHL-AAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCET--LVQEEEQFLSRLEEKSATL 844
|
490 500 510
....*....|....*....|....*....|...
gi 1465187875 645 QKKITNLKITCEKIEALEQENSELERENRKLKK 677
Cdd:TIGR00618 845 GEITHQLLKYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
252-1369 |
7.97e-07 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 54.67 E-value: 7.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKrlqqENMNLLSDARSARMYRDELDALREK----AVRVDK--- 324
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIK----AQINDLEDVADKAISNDDPEEIEKKieniVTKIDKkkn 1187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 325 LESEVSRYKERLHDIEFYKARVEELKEDNQVLLET--KTMLEDQLEGTRARSDKLHELEK-----ENLQLKAKLHDMEME 397
Cdd:TIGR01612 1188 IYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNlgKLFLEKIDEEKKKSEHMIKAMEAyiedlDEIKEKSPEIENEMG 1267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 398 RDMDRKKIEELM-------EENMTLEMAQKQSM----DESLHLGWELEQISRTSELSEAPQKSL------GHEVNELTSS 460
Cdd:TIGR01612 1268 IEMDIKAEMETFnishdddKDHHIISKKHDENIsdirEKSLKIIEDFSEESDINDIKKELQKNLldaqkhNSDINLYLNE 1347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 461 -----RLLKLEM------ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL----SKKVEILENEIVQEkqSLQNCQ 525
Cdd:TIGR01612 1348 ianiyNILKLNKikkiidEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeckSKIESTLDDKDIDE--CIKKIK 1425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 526 NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRqrsqISAEARVKDIEKENKILHESIKETSSKLSK 605
Cdd:TIGR01612 1426 ELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILK----IKKDNATNDHDFNINELKEHIDKSKGCKDE 1501
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 606 IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKtldsFKNL 685
Cdd:TIGR01612 1502 ADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKE----IKKE 1577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 686 TFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKElesekeqlkkglellkaSFKKTERLEVSYQGLDIEN 765
Cdd:TIGR01612 1578 KFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKIND-----------------CLKETESIEKKISSFSIDS 1640
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 766 QrlqktlensnkkiqqlESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKenkrlrqqa 845
Cdd:TIGR01612 1641 Q----------------DTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKK--------- 1695
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 846 eikdttleenNVKIGNLEKenktlskeigiykescvrLKELEKENKELVKRATIDIK-TLVTLREDLVSEKLKTQQMNND 924
Cdd:TIGR01612 1696 ----------NYEIGIIEK------------------IKEIAIANKEEIESIKELIEpTIENLISSFNTNDLEGIDPNEK 1747
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 925 LEKLTHELEKIGLNKERLlhdeqstddsrYKLLESKLESTLKKSL---EIKEEKIAA---LEARLEESTNYNQQLRQ-EL 997
Cdd:TIGR01612 1748 LEEYNTEIGDIYEEFIEL-----------YNIIAGCLETVSKEPItydEIKNTRINAqneFLKIIEIEKKSKSYLDDiEA 1816
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 998 KTVKKNYEALKQRQDeermvQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNN 1077
Cdd:TIGR01612 1817 KEFDRIINHFKKKLD-----HVNDKFTKEYSKINEGFDDISKSIENVKNSTDENLLFDILNKTKDAYAGIIGKKYYSYKD 1891
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1078 NLQAQILALQRQTVSLqeqNTTLQTQNAKLQVENSTLNSQStSLMNQNAQLLIQQSSLENENESVIKEREDlkslYDSLI 1157
Cdd:TIGR01612 1892 EAEKIFINISKLANSI---NIQIQNNSGIDLFDNINIAILS-SLDSEKEDTLKFIPSPEKEPEIYTKIRDS----YDTLL 1963
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1158 KDHEKLELLHERqasEYESLiskhgtlksahkNLEVEHRDLEDRYNQLLKQKGQLEDlekmLKVEQEKMLlenknhetva 1237
Cdd:TIGR01612 1964 DIFKKSQDLHKK---EQDTL------------NIIFENQQLYEKIQASNELKDTLSD----LKYKKEKIL---------- 2014
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1238 AEYKKLCGENDRLNHTYSQLLKETEVLQTDHKN-LKSLLNNSKLEQTRLEAEFS-KLKEQYQQLDITST-KLNNQCELLS 1314
Cdd:TIGR01612 2015 NDVKLLLHKFDELNKLSCDSQNYDTILELSKQDkIKEKIDNYEKEKEKFGIDFDvKAMEEKFDNDIKDIeKFENNYKHSE 2094
|
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*..
gi 1465187875 1315 QLKGNLEEENRHLLDQIQTLmlqNRTLLEQNMESKDLFH--VEQRQYIDKLNELRRQ 1369
Cdd:TIGR01612 2095 KDNHDFSEEKDNIIQSKKKL---KELTEAFNTEIKIIEDkiIEKNDLIDKLIEMRKE 2148
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
824-1146 |
9.55e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 54.30 E-value: 9.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKeigiYKESCVRLKELE-----KENKELVK-RA 897
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER----YQALLKEKREYEgyellKEKEALERqKE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 898 TIDiKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLEST------LKKSLEI 971
Cdd:TIGR02169 241 AIE-RQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLersiaeKERELED 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 972 KEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ-----RQDEERMVQSSPPISGEDNKWERESQETTRELLKVKD 1046
Cdd:TIGR02169 320 AEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEeyaelKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKR 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1047 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA 1126
Cdd:TIGR02169 400 EINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYD 479
|
330 340
....*....|....*....|
gi 1465187875 1127 QLLIQQSSLENENESVIKER 1146
Cdd:TIGR02169 480 RVEKELSKLQRELAEAEAQA 499
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
550-903 |
1.42e-06 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 53.51 E-value: 1.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 550 ERQIKILEQENEHLNQTVSSLRQrsQISAEARVKDIEKEN--KILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERA 627
Cdd:PTZ00108 998 EYLLGKLERELARLSNKVRFIKH--VINGELVITNAKKKDlvKELKKLGYVRFKDIIKKKSEKITAEEEEGAEEDDEADD 1075
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 628 EELENELHHLEKENELLQKKITNLkiTCEKIEALEQENSELERENRKLKKTldSFKNLtfQLESLEKENSQLDEEnlELR 707
Cdd:PTZ00108 1076 EDDEEELGAAVSYDYLLSMPIWSL--TKEKVEKLNAELEKKEKELEKLKNT--TPKDM--WLEDLDKFEEALEEQ--EEV 1147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 708 RNVESLKCASMKMAQLQlenKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Cdd:PTZ00108 1148 EEKEIAKEQRLKSKTKG---KASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSD 1224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 788 DLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:PTZ00108 1225 QEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSS 1304
|
330 340 350
....*....|....*....|....*....|....*.
gi 1465187875 868 TLSKEIGIYKEScvrlKELEKENKELVKRATIDIKT 903
Cdd:PTZ00108 1305 PTKKKVKKRLEG----SLAALKKKKKSEKKTARKKK 1336
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
577-695 |
1.56e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.86 E-value: 1.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 577 SAEARVKDIEKE-NKILHESIKETSSKLSKIEFEKRQ--IKKELEHYKEKGERAEELEnelhhlEKENELLQKKiTNLKi 653
Cdd:PRK12704 28 IAEAKIKEAEEEaKRILEEAKKEAEAIKKEALLEAKEeiHKLRNEFEKELRERRNELQ------KLEKRLLQKE-ENLD- 99
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1465187875 654 tcEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Cdd:PRK12704 100 --RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE 139
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
746-988 |
1.62e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.46 E-value: 1.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 746 ASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETS 825
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 826 QLEKDKKQLEKE-NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSkeigiykescvRLKELEKENKELVKRATIDIKTL 904
Cdd:COG4942 94 ELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQ-----------YLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLhdeqSTDDSRYKLLESKLEsTLKKSLEIKEEKIAALEARLE 984
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLL----ARLEKELAELAAELA-ELQQEAEELEALIARLEAEAA 237
|
....
gi 1465187875 985 ESTN 988
Cdd:COG4942 238 AAAE 241
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
505-858 |
2.07e-06 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 52.77 E-value: 2.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 505 KKVEILENEIVQEKQS-LQNCQNLSKDLMKEKAQLEKTIETLRENSER--------QIKILEQENEhlnqtVSSLRQRSQ 575
Cdd:pfam05622 30 KNSLQQENKKLQERLDqLESGDDSGTPGGKKYLLLQKQLEQLQEENFRletarddyRIKCEELEKE-----VLELQHRNE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 576 --ISAEARVKDIEKENKILhesiKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENE-----LHHLEKENELlqKKI 648
Cdd:pfam05622 105 elTSLAEEAQALKDEMDIL----RESSDKVKKLEATVETYKKKLEDLGDLRRQVKLLEERnaeymQRTLQLEEEL--KKA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 649 TNLKITCEKIEALEQE-NSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEN 727
Cdd:pfam05622 179 NALRGQLETYKRQVQElHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERDTLRETNEELRCAQLQQAELSQAD 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 728 KELESEKEQLKK-GLELLKASFKKT-ERLEVSYQGLDI-----ENQR---LQKTLENSNKKIQQLESEL-----QDLEME 792
Cdd:pfam05622 259 ALLSPSSDPGDNlAAEIMPAEIREKlIRLQHENKMLRLgqegsYRERlteLQQLLEDANRRKNELETQNrlanqRILELQ 338
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 793 NQT--LQKNLEEL----KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVK 858
Cdd:pfam05622 339 QQVeeLQKALQEQgskaEDSSLLKQKLEEHLEKLHEAQSELQKKKEQIEELEPKQDSNLAQKIDELQEALRK 410
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
661-1207 |
2.32e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 52.52 E-value: 2.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 661 LEQENSELERE----NRKLKKTLDSFKnlTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEkeq 736
Cdd:pfam10174 8 LQRENELLRREldikESKLGSSMNSIK--TFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDE--- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 737 lkkglelLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE--ELKISSKRlEQLE 814
Cdd:pfam10174 83 -------LRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEemELRIETQK-QTLG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 815 KENKSLEQ--ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLskeigiyKESCVRLKELEKENKE 892
Cdd:pfam10174 155 ARDESIKKllEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHL-------REELHRRNQLQPDPAK 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 893 lvkratidIKTLVTLREDLVSEKLKTQQMNNDLEkltheLEKIGLNKERLLHDEQSTDD--------SRYKLLESKLEsT 964
Cdd:pfam10174 228 --------TKALQTVIEMKDTKISSLERNIRDLE-----DEVQMLKTNGLLHTEDREEEikqmevykSHSKFMKNKID-Q 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 965 LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRqdeermvqsSPPISGEDNKWERESQETTRELLKV 1044
Cdd:pfam10174 294 LKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQR---------AAILQTEVDALRLRLEEKESFLNKK 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1045 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1124
Cdd:pfam10174 365 TKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEA 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1125 NA------QLLIQQSSLEN-----ENESVIKEREDLKSLYDSLIKDHEKLEL----LHERQASEYESLISKHGTLKSAHK 1189
Cdd:pfam10174 445 LSekeriiERLKEQREREDrerleELESLKKENKDLKEKVSALQPELTEKESslidLKEHASSLASSGLKKDSKLKSLEI 524
|
570
....*....|....*...
gi 1465187875 1190 NLEVEHRDLEDRYNQLLK 1207
Cdd:pfam10174 525 AVEQKKEECSKLENQLKK 542
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
247-850 |
3.24e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.53 E-value: 3.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 247 QHLSVELadaKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA-RMYRDELDALREKAVRVDKL 325
Cdd:pfam12128 261 SHLHFGY---KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvAKDRSELEALEDQHGAFLDA 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 326 ESEvsRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenLQLKAKLHDMEMERDMDRKKI 405
Cdd:pfam12128 338 DIE--TAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---------EQNNRDIAGIKDKLAKIREAR 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 406 EELMEENMTLEMAQKQSMDESLHLGweLEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN--QSLTKTVEELRTTV 483
Cdd:pfam12128 407 DRQLAVAEDDLQALESELREQLEAG--KLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENfdERIERAREEQEAAN 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 484 DSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN------------LSKDLMKEKAQLEKTIET------- 544
Cdd:pfam12128 485 AEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELqlfpqagtllhfLRKEAPDWEQSIGKVISPellhrtd 564
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 545 ----LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620
Cdd:pfam12128 565 ldpeVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFA 644
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 621 KEKGERAEElenELHHLEKENELLQKKITnlKITCEKIEALEQENSELERENRKLKKTLDSFknltfqLESLEKENSQLD 700
Cdd:pfam12128 645 RTALKNARL---DLRRLFDEKQSEKDKKN--KALAERKDSANERLNSLEAQLKQLDKKHQAW------LEEQKEQKREAR 713
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 701 EENLELRRNVESLKCASM----------------KMAQLQLENK--------------ELESEKEQLKKGLELLKASFKK 750
Cdd:pfam12128 714 TEKQAYWQVVEGALDAQLallkaaiaarrsgakaELKALETWYKrdlaslgvdpdviaKLKREIRTLERKIERIAVRRQE 793
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 751 TERLEVSYQG-LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQL- 827
Cdd:pfam12128 794 VLRYFDWYQEtWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEmERKASEKQQVRLSENLRGLRCEMSKLa 873
|
650 660
....*....|....*....|....*...
gi 1465187875 828 ----EKDKKQLEKE-NKRLRQQAEIKDT 850
Cdd:pfam12128 874 tlkeDANSEQAQGSiGERLAQLEDLKLK 901
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
762-1014 |
4.07e-06 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 51.85 E-value: 4.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 762 DIENQRLQKTLENS---NKKIQQLESELQDLEMENQTLQ----KNLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:PRK05771 39 ELSNERLRKLRSLLtklSEALDKLRSYLPKLNPLREEKKkvsvKSLEELiKDVEEELEKIEKEIKELEEEISELENEIKE 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 834 LEKENKRLRQqaeikdttLEENNVKIGNLeKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTlredLVS 913
Cdd:PRK05771 119 LEQEIERLEP--------WGNFDLDLSLL-LGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKGYVYVV----VVV 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 914 EKlktqqmnNDLEKLTHELEKIGLnkerllhdeqstddSRYKLLESKlesTLKKSLEIKEEKIAALEARLEEstnynqqL 993
Cdd:PRK05771 186 LK-------ELSDEVEEELKKLGF--------------ERLELEEEG---TPSELIREIKEELEEIEKERES-------L 234
|
250 260
....*....|....*....|.
gi 1465187875 994 RQELKTVKKNYEALKQRQDEE 1014
Cdd:PRK05771 235 LEELKELAKKYLEELLALYEY 255
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
253-714 |
5.35e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 51.44 E-value: 5.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAvrvDKLESEVSRY 332
Cdd:PRK01156 185 IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMK---NRYESEIKTA 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 333 KERLHDIEFYKARVEELKEDNQVLLETKTM------------------LEDQLEGTRARSDKLHELEKENLQLKAKLHD- 393
Cdd:PRK01156 262 ESDLSMELEKNNYYKELEERHMKIINDPVYknrnyindyfkykndienKKQILSNIDAEINKYHAIIKKLSVLQKDYNDy 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 394 MEMERDMD--RKKIEELMEENM-------TLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSrLLK 464
Cdd:PRK01156 342 IKKKSRYDdlNNQILELEGYEMdynsylkSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVK-LQD 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 465 LEMENQSLTKTVEELRTTVDSVEGNAS-----------------------------KILKMEKENQRLSKKVEILENEIV 515
Cdd:PRK01156 421 ISSKVSSLNQRIRALRENLDELSRNMEmlngqsvcpvcgttlgeeksnhiinhyneKKSRLEEKIREIEIEVKDIDEKIV 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 516 QEK-----------QSLQNCQNLSKDLMKEKAQLEKTIETLRENSER-----------QIKILEQENEHLNQTVSslrQR 573
Cdd:PRK01156 501 DLKkrkeyleseeiNKSINEYNKIESARADLEDIKIKINELKDKHDKyeeiknrykslKLEDLDSKRTSWLNALA---VI 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 574 SQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PRK01156 578 SLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKK 657
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 654 TCEKIEALEQENSEL-------ERENRKLKKTLDSFKNLTFQLESLEK----ENSQLDEENLELRRNVESLK 714
Cdd:PRK01156 658 QIAEIDSIIPDLKEItsrindiEDNLKKSRKALDDAKANRARLESTIEilrtRINELSDRINDINETLESMK 729
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
958-1299 |
5.53e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 5.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 958 ESKLESTLKKsLEIKEEKIAALEARLEESTNYNQQLRQElKTVKKNYEALKQRqdeermvqssppisgednKWERESQET 1037
Cdd:TIGR02169 169 DRKKEKALEE-LEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKE------------------KREYEGYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1038 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNAKLQVENSTL-- 1114
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLer 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1115 -----NSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHK 1189
Cdd:TIGR02169 309 siaekERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1190 NLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMlleNKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHK 1269
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADL---NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
330 340 350
....*....|....*....|....*....|
gi 1465187875 1270 NLKSLLNNSKLEQTRLEAEFSKLKEQYQQL 1299
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQRELAEA 495
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
288-788 |
6.14e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.31 E-value: 6.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 288 LKRLQQENMNLLS-DARSARMYRDELDALREKavrVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQ 366
Cdd:COG4717 48 LERLEKEADELFKpQGRKPELNLKELKELEEE---LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 367 LEgtrarsdkLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQsmdeslhlgweleqisrtselseap 446
Cdd:COG4717 125 LQ--------LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAE------------------------- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 447 QKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKIlkmEKENQRLSKKVEILENEIV--QEKQSLQNC 524
Cdd:COG4717 172 LAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA---QEELEELEEELEQLENELEaaALEERLKEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 525 QNLSKDL--MKEKAQLEKTIETLRENSERQIKILEQenehLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSK 602
Cdd:COG4717 249 RLLLLIAaaLLALLGLGGSLLSLILTIAGVLFLVLG----LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEEL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 603 LSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENEL--LQKKITNL--KITCEKIEALEQeNSELERENRKLKKT 678
Cdd:COG4717 325 LAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLeeLEQEIAALlaEAGVEDEEELRA-ALEQAEEYQELKEE 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 679 LDSFKN-LTFQLESLEKENSQLDEENL--ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKtERLE 755
Cdd:COG4717 404 LEELEEqLEELLGELEELLEALDEEELeeELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQEL-EELK 482
|
490 500 510
....*....|....*....|....*....|...
gi 1465187875 756 VSYQGLDIENQRLQKTLENSNKKIQQLESELQD 788
Cdd:COG4717 483 AELRELAEEWAALKLALELLEEAREEYREERLP 515
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
550-985 |
7.04e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.92 E-value: 7.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH----ESIKETSSKLSKIEFEKRQIKKELEHYKEKGE 625
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKleklLQLLPLYQELEALEAELAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 626 RAEELENELHHLEKENELLQKKITN------------LKITCEKIEALEQENSELERENRKLKKTLDsfkNLTFQLESLE 693
Cdd:COG4717 157 ELRELEEELEELEAELAELQEELEElleqlslateeeLQDLAEELEELQQRLAELEEELEEAQEELE---ELEEELEQLE 233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 694 KENSQLDEENlELRRNVESLKCASMkMAQLQLENKELESEKEQLKKGLELL---------------KASFKKTERLEVSY 758
Cdd:COG4717 234 NELEAAALEE-RLKEARLLLLIAAA-LLALLGLGGSLLSLILTIAGVLFLVlgllallflllarekASLGKEAEELQALP 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 759 QGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK--ISSKRLEQLEKENKSLEQETSQleKDKKQLEK 836
Cdd:COG4717 312 ALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEelEEELQLEELEQEIAALLAEAGV--EDEEELRA 389
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 837 ENKRLRQQAEIKDtTLEENNVKIGNLEKENKTLSKEIGiykescvrLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
Cdd:COG4717 390 ALEQAEEYQELKE-ELEELEEQLEELLGELEELLEALD--------EEELEEELEELEEELEELEEELEELREELAELEA 460
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1465187875 917 KTQQMNND--LEKLTHELEKIglnKERLlhDEQSTDDSRYKLLESKLESTLKkslEIKEEKIAALEARLEE 985
Cdd:COG4717 461 ELEQLEEDgeLAELLQELEEL---KAEL--RELAEEWAALKLALELLEEARE---EYREERLPPVLERASE 523
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
494-1301 |
7.15e-06 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 51.37 E-value: 7.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 494 LKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEqenehLNQTVSSLRQR 573
Cdd:PTZ00440 439 LEIIEIKKKYDEKINELKKSINQLKTLISIMKSFYDLIISEKDSMDSKEKKESSDSNYQEKVDE-----LLQIINSIKEK 513
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 574 SQISAEaRVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PTZ00440 514 NNIVNN-NFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENVDHIKDIISLNDE 592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 654 TCEKIEALEQENSELERENRKLKKtldsfknltfqleslEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733
Cdd:PTZ00440 593 IDNIIQQIEELINEALFNKEKFIN---------------EKNDLQEKVKYILNKFYKGDLQELLDELSHFLDDHKYLYHE 657
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 734 KEQLKKGLELLKASFKKTERLEvsyqgldienqrlQKTLENSNKKIQQLESELQDL-EMENQTLQKNLEELKIS-SKRLE 811
Cdd:PTZ00440 658 AKSKEDLQTLLNTSKNEYEKLE-------------FMKSDNIDNIIKNLKKELQNLlSLKENIIKKQLNNIEQDiSNSLN 724
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgnleKENKTLSKEIGIYKESCVRLKELEKENK 891
Cdd:PTZ00440 725 QYTIKYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDL----PDGKNTYEEFLQYKDTILNKENKISNDI 800
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 892 ELVKRATIDIKTLVTLREDLVsEKLKTQQMNNDlEKLTHELEKIGLNKERLLHDEqstDDSRYKLLESKLESTLKKsLEI 971
Cdd:PTZ00440 801 NILKENKKNNQDLLNSYNILI-QKLEAHTEKND-EELKQLLQKFPTEDENLNLKE---LEKEFNENNQIVDNIIKD-IEN 874
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 972 KEEKIAALEaRLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKwERESQETTRELLKVKDRLIEV 1051
Cdd:PTZ00440 875 MNKNINIIK-TLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNEK-LNLLNNLNKEKEKIEKQLSDT 952
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1052 ERNNATLQAEKQaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENstlnsqstslmnqnaqlliq 1131
Cdd:PTZ00440 953 KINNLKMQIEKT-LEYYDKSKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILN-------------------- 1011
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1132 qsslENENESVIKEREDLKSLYDSLIKdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1211
Cdd:PTZ00440 1012 ----KKIDDLIKKQHDDIIELIDKLIK--EKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEK 1085
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1212 LEDLEKMLKVEQEKML-LENKNHETVAAeykkLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEaEFS 1290
Cdd:PTZ00440 1086 VEALLKKIDENKNKLIeIKNKSHEHVVN----ADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKELENMNLEDITLN-EVN 1160
|
810
....*....|.
gi 1465187875 1291 KLKEQYQQLDI 1301
Cdd:PTZ00440 1161 EIEIEYERILI 1171
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
578-844 |
7.15e-06 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 51.01 E-value: 7.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 578 AEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK-GERAEELENELHHLEKENELLQKKITN------ 650
Cdd:pfam06160 98 IEEDIKQILEELDELLESEEKNREEVEELKDKYRELRKTLLANRFSyGPAIDELEKQLAEIEEEFSQFEELTESgdylea 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 651 ---LKITCEKIEALEQENSELERENRKLKKTL-DSFKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCASMKMAQLQ 724
Cdd:pfam06160 178 revLEKLEEETDALEELMEDIPPLYEELKTELpDQLEELKEGYREMEEEGYALEHLNVDKEIQQleEQLEENLALLENLE 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 725 LE-----NKELESEKEQLKKGLE-----------LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESE 785
Cdd:pfam06160 258 LDeaeeaLEEIEERIDQLYDLLEkevdakkyvekNLPEIEDYLEHAEEQNKELKEELERVQQSYTLNENeleRVRGLEKQ 337
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 786 LQDLEMENQTLQKNLEE-----------LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam06160 338 LEELEKRYDEIVERLEEkevayselqeeLEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLE 407
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
340-1031 |
7.34e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.12 E-value: 7.34e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 340 EFYKARVEELKEDNQVLLETKTMLEDQLEgTRARSDKLH---ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416
Cdd:TIGR00618 156 QFLKAKSKEKKELLMNLFPLDQYTQLALM-EFAKKKSLHgkaELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 417 MAQKQSMDESLHLGWEL--EQISRTSELSEApQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKIL 494
Cdd:TIGR00618 235 LQQTQQSHAYLTQKREAqeEQLKKQQLLKQL-RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIH 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE---TLRENSERQiKILEQENEHLNQTVSSLR 571
Cdd:TIGR00618 314 TELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEvatSIREISCQQ-HTLTQHIHTLQQQKTTLT 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 572 QRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKrQIKKELEHYKEKgerAEELENELHHLEKENELLQKKITNL 651
Cdd:TIGR00618 393 QKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKK-QQELQQRYAELC---AAAITCTAQCEKLEKIHLQESAQSL 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 652 KitcEKIEALEQENSELERENRKlKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM----------- 720
Cdd:TIGR00618 469 K---EREQQLQTKEQIHLQETRK-KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGeqtyaqletse 544
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 721 ----AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTL 796
Cdd:TIGR00618 545 edvyHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPE 624
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKkqlEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIY 876
Cdd:TIGR00618 625 QDLQDVRLHLQQCSQELALKLTALHALQLTLTQER---VREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQ 701
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 877 KESCVR-----LKELEKENKELVKRATIDIKTLvTLREDLVSEKLKTQQMNNDlEKLTHELEKIGLNKERLLHDEQS--- 948
Cdd:TIGR00618 702 CQTLLRelethIEEYDREFNEIENASSSLGSDL-AAREDALNQSLKELMHQAR-TVLKARTEAHFNNNEEVTAALQTgae 779
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 949 ----------------TDDSRYKLLESKLESTLKKSLEIKE---EKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ 1009
Cdd:TIGR00618 780 lshlaaeiqffnrlreEDTHLLKTLEAEIGQEIPSDEDILNlqcETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSK 859
|
730 740
....*....|....*....|..
gi 1465187875 1010 RQDEerMVQSSPPISGEDNKWE 1031
Cdd:TIGR00618 860 QLAQ--LTQEQAKIIQLSDKLN 879
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
241-622 |
7.43e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 51.06 E-value: 7.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllsDARSARMYRDEldalreKAV 320
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDD---DHNRASMQRDE------AIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 321 RVDKLESEVSRYKERLHDIEFykarvEELKEDNQVLlETKTMLEDQlegtrARSDKLHELEK---ENLQLKAKLHDMEME 397
Cdd:PLN02939 110 AIDNEQQTNSKDGEQLSDFQL-----EDLVGMIQNA-EKNILLLNQ-----ARLQALEDLEKiltEKEALQGKINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 398 RDMDRKKIEELMEENMTLEMAQKQsmdeslhLGWELEQISRTSELSEAPQKSLGHEVNELTSsrllklemENQSLTKTVE 477
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQ-------LEKLRNELLIRGATEGLCVHSLSKELDVLKE--------ENMLLKDDIQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA------------QLEKTIETL 545
Cdd:PLN02939 244 FLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVenlqdlldratnQVEKAALVL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 546 RENSERQIKI------LEQEN---------EHLNQTVSSLRQRSQISAEarvkDIEKENKILHESIKETSSKLSKIEFEK 610
Cdd:PLN02939 324 DQNQDLRDKVdkleasLKEANvskfssykvELLQQKLKLLEERLQASDH----EIHSYIQLYQESIKEFQDTLSKLKEES 399
|
410
....*....|..
gi 1465187875 611 RqiKKELEHYKE 622
Cdd:PLN02939 400 K--KRSLEHPAD 409
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
519-714 |
7.73e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.07 E-value: 7.73e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 519 QSLQNCQNLS---KDLMKEKAQLEKTIETLREN-------------SERQIKILEQENEH---LNQTVSSLRQRSQISAE 579
Cdd:COG4913 201 QSFKPIGDLDdfvREYMLEEPDTFEAADALVEHfddlerahealedAREQIELLEPIRELaerYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 580 ARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK------------GERAEELENELHHLEKENELLQKK 647
Cdd:COG4913 281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEldeleaqirgngGDRLEQLEREIERLERELEERERR 360
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 648 ITNLKITCEKIE-ALEQENSELERENRKLKKTLDSFKNLTFQLE----SLEKENSQLDEENLELRRNVESLK 714
Cdd:COG4913 361 RARLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLE 432
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
347-580 |
1.22e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDES 426
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 427 LHLGWELEQISRTSELSEApqkslghevneLTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKK 506
Cdd:COG4942 107 AELLRALYRLGRQPPLALL-----------LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1465187875 507 VEILENEIVQEKQSLQncqnlskDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Cdd:COG4942 176 LEALLAELEEERAALE-------ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
882-1374 |
1.28e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.45 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLK-TQQMNNDLEKLTHELEKIGLNKERLlhdeqstDDSRYKLLESK 960
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLReINEISSELPELREELEKLEKEVKEL-------EELKEEIEELE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 961 LE-STLKKSLEIKEEKIAALEARLEESTNYNQQLRQ------ELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERE 1033
Cdd:PRK03918 245 KElESLEGSKRKLEEKIRELEERIEELKKEIEELEEkvkelkELKEKAEEYIKLSEFYEEYLDELRE--IEKRLSRLEEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1034 SQETTR---ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETqnnnlqaqILALQRQTVSLQEQNTTLQTQNAKLQVE 1110
Cdd:PRK03918 323 INGIEErikELEEKEERLEELKKKLKELEKRLEELEERHELYEE--------AKAKKEELERLKKRLTGLTPEKLEKELE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1111 NstLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKS------LYDSLIKDHEKLELLHERQASeyesliskhgtl 1184
Cdd:PRK03918 395 E--LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpVCGRELTEEHRKELLEEYTAE------------ 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1185 ksaHKNLEVEHRDLEDRYNQLLKQkgqLEDLEKMLKVEQEKMLLEnknheTVAAEYKKLCGENDRLNhtysqlLKETEVL 1264
Cdd:PRK03918 461 ---LKRIEKELKEIEEKERKLRKE---LRELEKVLKKESELIKLK-----ELAEQLKELEEKLKKYN------LEELEKK 523
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1265 QTDHKNLKSLLNNSKLEQTRLEAEFSKLKEqyqqlditstkLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQ 1344
Cdd:PRK03918 524 AEEYEKLKEKLIKLKGEIKSLKKELEKLEE-----------LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592
|
490 500 510
....*....|....*....|....*....|
gi 1465187875 1345 NMESKDLFHVEQRQYIDKLNELRRQKEKLE 1374
Cdd:PRK03918 593 RLKELEPFYNEYLELKDAEKELEREEKELK 622
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
554-695 |
1.35e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.78 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 554 KILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKilhesiKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE-LEN 632
Cdd:PRK12704 27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAK------EEIHKLRNEFEKELRERRNELQKLEKRLLQKEEnLDR 100
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1465187875 633 ELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNLT------FQLESLEKE 695
Cdd:PRK12704 101 KLELLEKREEELEKKEKELE---QKQQELEKKEEELEELIEEQLQELERISGLTaeeakeILLEKVEEE 166
|
|
| SH3_and_anchor |
TIGR04211 |
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ... |
716-826 |
1.37e-05 |
|
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.
Pssm-ID: 275056 [Multi-domain] Cd Length: 198 Bit Score: 48.08 E-value: 1.37e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 716 ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKterLEVSYQGLDIENQRLQKTLEnsnkKIQQLESELQDLEMENQT 795
Cdd:TIGR04211 64 ARERLPELQQELAELQEELAELQEQLAELRQENQE---LKQQLSTLEAELEELQKELE----RIKQISANAIELDEENRE 136
|
90 100 110
....*....|....*....|....*....|.
gi 1465187875 796 LQKNLEELKissKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR04211 137 LREELAELK---QENEALEAENERLQENEQR 164
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
583-844 |
1.43e-05 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 49.83 E-value: 1.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 583 KDIEKENKILHESIKETSSKLSKIEFEKR--------QIKKELEHYKEKGERAEELENELHHLEKENEL--LQKKITNLK 652
Cdd:PRK04778 132 LESEEKNREEVEQLKDLYRELRKSLLANRfsfgpaldELEKQLENLEEEFSQFVELTESGDYVEAREILdqLEEELAALE 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 653 ITCEKIEALEqenselerenRKLKKTL-DSFKNLTFQLESLEKENSQLDEENL--ELRRNVESLKCASMKMAQLQLE--- 726
Cdd:PRK04778 212 QIMEEIPELL----------KELQTELpDQLQELKAGYRELVEEGYHLDHLDIekEIQDLKEQIDENLALLEELDLDeae 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 727 --NKELESEKEQL----------KKGLELLKASFKKT-ERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESELQDLE 790
Cdd:PRK04778 282 ekNEEIQERIDQLydilerevkaRKYVEKNSDTLPDFlEHAKEQNKELKEEIDRVKQSYTLNESeleSVRQLEKQLESLE 361
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1465187875 791 MENQTLQKNL-----------EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:PRK04778 362 KQYDEITERIaeqeiayselqEELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNK 426
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
820-1382 |
1.70e-05 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 49.72 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 820 LEQETSQLEKDKKQLEKENKRLRQ---QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK-------E 889
Cdd:pfam05483 101 LKQKENKLQENRKIIEAQRKAIQElqfENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKkyeyereE 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 890 NKELVKRATIDIKTLVTLREDLVSEKLKTQ-----QMNNDLEKLTH---ELEKIGLNKER---LLHDEQSTDDSRYKLLE 958
Cdd:pfam05483 181 TRQVYMDLNNNIEKMILAFEELRVQAENARlemhfKLKEDHEKIQHleeEYKKEINDKEKqvsLLLIQITEKENKMKDLT 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 959 SKLESTLKKSLEIkEEKIAALEARLEESTNYNQQLRQELKTVKKNYE--ALKQRQDEERMVQSSPPISGEDNKWERESQE 1036
Cdd:pfam05483 261 FLLEESRDKANQL-EEKTKLQDENLKELIEKKDHLTKELEDIKMSLQrsMSTQKALEEDLQIATKTICQLTEEKEAQMEE 339
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1037 TTRELLKVKDRLIEVERNNATLQaekQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQntTLQTQNAKLQVEnstlns 1116
Cdd:pfam05483 340 LNKAKAAHSFVVTEFEATTCSLE---ELLRTEQQRLEKNEDQLKIITMELQKKSSELEEM--TKFKNNKEVELE------ 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1117 QSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHR 1196
Cdd:pfam05483 409 ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNI 488
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1197 DLEDRYNQLLKQKgqledleKMLKVEQEKMLLENKNHETVAAEYKKlcgendrlnhTYSQLLKETEVLQTDHKNLKSLLN 1276
Cdd:pfam05483 489 ELTAHCDKLLLEN-------KELTQEASDMTLELKKHQEDIINCKK----------QEERMLKQIENLEEKEMNLRDELE 551
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1277 NSKLE----QTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLF 1352
Cdd:pfam05483 552 SVREEfiqkGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQL 631
|
570 580 590
....*....|....*....|....*....|
gi 1465187875 1353 HVEQRQYIDKLNELRRQKEKLEEkIMDQYK 1382
Cdd:pfam05483 632 NAYEIKVNKLELELASAKQKFEE-IIDNYQ 660
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
371-686 |
1.70e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.74 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 371 RARSDKLHELEKENLQLKAKLHDMEMERdmdRKKIEEL-------MEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 443
Cdd:pfam17380 287 RQQQEKFEKMEQERLRQEKEEKAREVER---RRKLEEAekarqaeMDRQAAIYAEQERMAMERERELERIRQEERKRELE 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 444 EAPQKSLGHEVNELtsSRLLKLEMENQsltKTVEELRTTVDSvegnASKILKMEKENQRLSKKVEILENEIVQEKQSLQn 523
Cdd:pfam17380 364 RIRQEEIAMEISRM--RELERLQMERQ---QKNERVRQELEA----ARKVKILEEERQRKIQQQKVEMEQIRAEQEEAR- 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 524 cQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETSSKL 603
Cdd:pfam17380 434 -QREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAE----EQRRKILEKELEERKQAM 508
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 604 SKIEFEKRQIKKELEH-----YKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELER--ENRKLK 676
Cdd:pfam17380 509 IEEERKRKLLEKEMEErqkaiYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQivESEKAR 588
|
330
....*....|
gi 1465187875 677 KTLDSFKNLT 686
Cdd:pfam17380 589 AEYEATTPIT 598
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
657-867 |
1.71e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.44 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 657 KIEALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQ 736
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQA---ELEELNEEYNELQAELEALQAEIDKLQ------AEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 737 LKKGLELLKASFKKTERLEV-----SYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLE 811
Cdd:COG3883 88 LGERARALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELE---ALKA 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 1465187875 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:COG3883 165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1138-1375 |
1.91e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.94 E-value: 1.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1138 ENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQkgqLEDLEK 1217
Cdd:COG1196 226 EAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAE---LARLEQ 302
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1218 MLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQ 1297
Cdd:COG1196 303 DIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE 382
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 1298 QLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEE 1375
Cdd:COG1196 383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
532-855 |
2.49e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 49.19 E-value: 2.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 532 MKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEAR---VKDIEKENKILHESIKETSSK--LSKI 606
Cdd:COG5185 235 LKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENAnnlIKQFENTKEKIAEYTKSIDIKkaTESL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 607 EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEAlEQENSELERENRKLKKTLDSFKNLT 686
Cdd:COG5185 315 EEQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVG-EVELSKSSEELDSFKDTIESTKESL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 687 FQ------------LESLEKENSQLDEENLELRRNVESlkcASMKMAQLQLENKELESEKEQLKKglellKASFKKTERL 754
Cdd:COG5185 394 DEipqnqrgyaqeiLATLEDTLKAADRQIEELQRQIEQ---ATSSNEEVSKLLNELISELNKVMR-----EADEESQSRL 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 755 EVSYQGLdieNQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:COG5185 466 EEAYDEI---NRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLErQLEGVRSKLDQVAESLKDFMRARGYAHILALE 542
|
330 340
....*....|....*....|..
gi 1465187875 834 LEKENKRLRQQAEIKDTTLEEN 855
Cdd:COG5185 543 NLIPASELIQASNAKTDGQAAN 564
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
682-1344 |
2.56e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 49.45 E-value: 2.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 682 FKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGL 761
Cdd:pfam12128 236 IMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADA 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 762 DIENQRLQKTLENSNKKIQQ---LESELQDLEMENQtLQKNLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQ----- 833
Cdd:pfam12128 316 AVAKDRSELEALEDQHGAFLdadIETAAADQEQLPS-WQSELENL---EERLKALTGKHQDVTAKYNRRRSKIKEqnnrd 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKE-NKTLSKEIGIYKESCVRLKELEKENKELVKRATIdiktlvtlredlv 912
Cdd:pfam12128 392 IAGIKDKLAKIREARDRQLAVAEDDLQALESElREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATA------------- 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 913 SEKLKTQQMNND--LEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLEsKLESTLKKSLEIKEEKIAALEARLEESTNYN 990
Cdd:pfam12128 459 TPELLLQLENFDerIERAREEQEAANAEVERLQSELRQARKRRDQASE-ALRQASRRLEERQSALDELELQLFPQAGTLL 537
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 991 QQLRQELKTVKKNY-----EALKQRQDEERMVQSSPPISG-------------EDNKWERESQETTRELLKVKDrlieve 1052
Cdd:pfam12128 538 HFLRKEAPDWEQSIgkvisPELLHRTDLDPEVWDGSVGGElnlygvkldlkriDVPEWAASEEELRERLDKAEE------ 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1053 rnnaTLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQlliQQ 1132
Cdd:pfam12128 612 ----ALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANE---RL 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1133 SSLENENESVIKEREDLKSLYDSLIKDH--EKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKG 1210
Cdd:pfam12128 685 NSLEAQLKQLDKKHQAWLEEQKEQKREArtEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLG 764
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1211 QleDLEKMLKVEQEKMLLENKnHETVAAEYKKLCGENDRLNHTYSQ-------LLKETEVLQTDHK-NLKSLLNNSKLEQ 1282
Cdd:pfam12128 765 V--DPDVIAKLKREIRTLERK-IERIAVRRQEVLRYFDWYQETWLQrrprlatQLSNIERAISELQqQLARLIADTKLRR 841
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1465187875 1283 TRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLK-----GNLEEENRHLLDQIQTLMLQNRTLLEQ 1344
Cdd:pfam12128 842 AKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKedansEQAQGSIGERLAQLEDLKLKRDYLSES 908
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
716-1070 |
3.16e-05 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 49.13 E-value: 3.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 716 ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKT--ERLEVSYQGLDIENQRLQKTLENS---NKKIQQLESELQDLE 790
Cdd:PLN02939 33 VSCRARRRGFSSQQKKKRGKNIAPKQRSSNSKLQSNtdENGQLENTSLRTVMELPQKSTSSDddhNRASMQRDEAIAAID 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 791 MENQTLQKNLEELkiSSKRLEQL-------EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgnle 863
Cdd:PLN02939 113 NEQQTNSKDGEQL--SDFQLEDLvgmiqnaEKNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARI---- 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 864 kenkTLSKEIGIYKEscVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERL- 942
Cdd:PLN02939 187 ----KLAAQEKIHVE--ILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEERVf 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 943 -LHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEestNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP 1021
Cdd:PLN02939 261 kLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVE---NLQDLLDRATNQVEKAALVLDQNQDLRDKVDKLE 337
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1465187875 1022 PISGEDNKWERESQETtrELLKVKDRLIEvERnnatLQAEKQALKTQLK 1070
Cdd:PLN02939 338 ASLKEANVSKFSSYKV--ELLQQKLKLLE-ER----LQASDHEIHSYIQ 379
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
792-1089 |
3.19e-05 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 48.03 E-value: 3.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Cdd:pfam09728 2 AARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 872 EIGIYK-ESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTD 950
Cdd:pfam09728 82 QNKKLKeESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELREKLKSLIEQYELRELHFEKLLKTK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 951 DSRYKLLESKLESTL----KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ------------RQDEE 1014
Cdd:pfam09728 162 ELEVQLAEAKLQQATeeeeKKAQEKEVAKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDtlnksnevfttfKKEME 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1465187875 1015 RMVQSSPPISGEDNKWERESQETTRELLKvkdrlievernnatLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Cdd:pfam09728 242 KMSKKIKKLEKENLTWKRKWEKSNKALLE--------------MAEERQKLKEELEKLQKKLEKLENLCRALQAE 302
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
464-681 |
3.59e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 3.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 464 KLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 544 TLRENSERQIKILeQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK 623
Cdd:COG4942 101 AQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1465187875 624 GERAEELENELHHLEKENELLQKKITnlkitcEKIEALEQENSELERENRKLKKTLDS 681
Cdd:COG4942 180 LAELEEERAALEALKAERQKLLARLE------KELAELAAELAELQQEAEELEALIAR 231
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1026-1211 |
3.74e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.29 E-value: 3.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1026 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQtvsLQEQNTTLQTQNA 1105
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAE---IEERREELGERAR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1106 KLQVENST-------LNSQSTS-----------LMNQNAQLLIQQSS----LENENESVIKEREDLKSLYDSLIKDHEKL 1163
Cdd:COG3883 94 ALYRSGGSvsyldvlLGSESFSdfldrlsalskIADADADLLEELKAdkaeLEAKKAELEAKLAELEALKAELEAAKAEL 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 1465187875 1164 ELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1211
Cdd:COG3883 174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
729-926 |
4.02e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 48.39 E-value: 4.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 729 ELESEKEQLKKGLELLKASFKKT-----ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Cdd:PRK05771 47 KLRSLLTKLSEALDKLRSYLPKLnplreEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 804 K----ISSKrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT---------TLEENNVKIGNLEKEN---- 866
Cdd:PRK05771 127 EpwgnFDLD--LSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDkgyvyvvvvVLKELSDEVEEELKKLgfer 204
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 867 ------KTLSKEIGIYKEscvRLKELEKE----NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Cdd:PRK05771 205 leleeeGTPSELIREIKE---ELEEIEKEreslLEELKELAKKYLEELLALYEYLEIELERAEALSKFLK 271
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
957-1120 |
4.07e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 47.90 E-value: 4.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 957 LESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE--ERMVQSSPPISGED------- 1027
Cdd:COG3883 35 AQAELDA-LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraRALYRSGGSVSYLDvllgses 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1028 --------NKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTT 1099
Cdd:COG3883 114 fsdfldrlSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAA 193
|
170 180
....*....|....*....|.
gi 1465187875 1100 LQTQNAKLQVENSTLNSQSTS 1120
Cdd:COG3883 194 AEAQLAELEAELAAAEAAAAA 214
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
979-1213 |
4.13e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.47 E-value: 4.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 979 LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERmvqssppisgEDNKWERESQETTRELlkvkDRLIEVERNNATL 1058
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFR----------QKNGLVDLSEEAKLLL----QQLSELESQLAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1059 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVsLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1138
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1465187875 1139 NESVIkerEDLKSLYDSLIKDHEKLEllheRQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLE 1213
Cdd:COG3206 311 AQRIL---ASLEAELEALQAREASLQ----AQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
499-852 |
4.85e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 48.41 E-value: 4.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 499 ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLektietlrenSERQiKILEQE----NEHLNQTVSSLRQRS 574
Cdd:COG3096 279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEEL----------SARE-SDLEQDyqaaSDHLNLVQTALRQQE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 575 QI--------SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENELHHLEKENE 642
Cdd:COG3096 348 KIeryqedleELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQqaldVQQTRAIQYQQAVQALEKARA 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 643 LLQK---KITNLKITCEKIEALEQENSELERENR-KLKKTLDSFKNLTFQLESLEK-----ENSQLDEENLELRRNVESL 713
Cdd:COG3096 428 LCGLpdlTPENAEDYLAAFRAKEQQATEEVLELEqKLSVADAARRQFEKAYELVCKiagevERSQAWQTARELLRRYRSQ 507
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKT-------ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Cdd:COG3096 508 QALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIgqqldaaEELEELLAELEAQLEELEEQAAEAVEQRSELRQQL 587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 787 QDLEMENQTL----------QKNLEELK------------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:COG3096 588 EQLRARIKELaarapawlaaQDALERLReqsgealadsqeVTAAMQQLLERE-REATVERDELAARKQALESQIERLSQP 666
|
....*...
gi 1465187875 845 AEIKDTTL 852
Cdd:COG3096 667 GGAEDPRL 674
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
262-368 |
5.53e-05 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 48.15 E-value: 5.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENmNLLSDARSARmYRDELDALREKAvrvDKLESEVSRYKERLHDIEF 341
Cdd:COG0542 401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQ-DEASFERLAE-LRDELAELEEEL---EALKARWEAEKELIEEIQE 475
|
90 100
....*....|....*....|....*..
gi 1465187875 342 YKARVEELKEDNQVLLETKTMLEDQLE 368
Cdd:COG0542 476 LKEELEQRYGKIPELEKELAELEEELA 502
|
|
| mreC |
TIGR00219 |
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ... |
825-943 |
5.66e-05 |
|
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. Cells defective in MreC are round. Species with MreC include many of the Proteobacteria, Gram-positives, and spirochetes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 129323 [Multi-domain] Cd Length: 283 Bit Score: 47.16 E-value: 5.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEennVKIGNLEKENKTLSKEIGIYKescvRLKElEKENKELVKRATIDIKTL 904
Cdd:TIGR00219 62 SENLKDVNNLEYENYKLRQELLKKNQQLE---ILTQNLKQENVRLRELLNSPL----SSDE-YKISAEVIYLNYDNYSTQ 133
|
90 100 110
....*....|....*....|....*....|....*....
gi 1465187875 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL 943
Cdd:TIGR00219 134 VVINKGFNDGVYKDMPVIADGKGLVGKVVSVGSNTSRVL 172
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
599-924 |
6.32e-05 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 47.11 E-value: 6.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 599 TSSKLSKIEFEKRQIKKELEHYKEKgeraeELENELHHLEKENELLQKKITNLKITCEKIEAleqenselerenrKLKKT 678
Cdd:pfam15905 52 TARKVKSLELKKKSQKNLKESKDQK-----ELEKEIRALVQERGEQDKRLQALEEELEKVEA-------------KLNAA 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 679 LDSFKNLTFQLESLEKENSQLDEENlELRRNVESLKCASMKMAQLQLENKELESEKEQlkkglellkasfkKTERLEVSY 758
Cdd:pfam15905 114 VREKTSLSASVASLEKQLLELTRVN-ELLKAKFSEDGTQKKMSSLSMELMKLRNKLEA-------------KMKEVMAKQ 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 759 QGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:pfam15905 180 EGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEI 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 839 KRLRQQAEIKDTTLEENnvkignlekenktlskeigiYKESCVRLKELEKENKELVKRATIDIKTLV----TLREDLVSE 914
Cdd:pfam15905 260 ESLKQSLEEKEQELSKQ--------------------IKDLNEKCKLLESEKEELLREYEEKEQTLNaeleELKEKLTLE 319
|
330
....*....|
gi 1465187875 915 KLKTQQMNND 924
Cdd:pfam15905 320 EQEHQKLQQK 329
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
719-837 |
6.58e-05 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 44.60 E-value: 6.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLEselQDLEMENQTLQK 798
Cdd:pfam12718 22 KVKELEQENLEKEQEIKSLTHKNQQLEEEVEKLEEQLKEAKEKAEESEKLKTNNENLTRKIQLLE---EELEESDKRLKE 98
|
90 100 110
....*....|....*....|....*....|....*....
gi 1465187875 799 NLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:pfam12718 99 TTEKLRETDVKAEHLERKVQALEQERDEWEKKYEELEEK 137
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
685-1073 |
7.34e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.58 E-value: 7.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 685 LTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA-QLQLENKELESEKEQLKkglELLKASFKKTERLEVSYQGLDI 763
Cdd:pfam07888 32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDReQWERQRRELESRVAELK---EELRQSREKHEELEEKYKELSA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 764 -------ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENkslEQETSQLEKDKKQLEK 836
Cdd:pfam07888 109 sseelseEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE---EAERKQLQAKLQQTEE 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 837 ENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
Cdd:pfam07888 186 ELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAA 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 917 KTQQMNNDLEKLTHELEKIGLNkerllhdeqsTDDSRYKLLE-----SKLESTLKKSLEIKEEKIAALEA---RLEESTN 988
Cdd:pfam07888 266 QRDRTQAELHQARLQAAQLTLQ----------LADASLALREgrarwAQERETLQQSAEADKDRIEKLSAelqRLEERLQ 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 989 YNQQLRQELKTvkknyeALKQRQDEERMVQSsppisgednkweresqETTRELLKVKDRLIEVERNNATLQAEKQALKTQ 1068
Cdd:pfam07888 336 EERMEREKLEV------ELGREKDCNRVQLS----------------ESRRELQELKASLRVAQKEKEQLQAEKQELLEY 393
|
....*
gi 1465187875 1069 LKQLE 1073
Cdd:pfam07888 394 IRQLE 398
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1039-1224 |
7.88e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.70 E-value: 7.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1039 RELLKVKDRLIEVER---------NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQv 1109
Cdd:COG3206 182 EQLPELRKELEEAEAaleefrqknGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELL- 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1110 ENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLydslikdhekLELLHERQASEYESLISKHGTLKSAHK 1189
Cdd:COG3206 261 QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAAL----------RAQLQQEAQRILASLEAELEALQAREA 330
|
170 180 190
....*....|....*....|....*....|....*
gi 1465187875 1190 NLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQE 1224
Cdd:COG3206 331 SLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
578-708 |
9.29e-05 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 47.55 E-value: 9.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 578 AEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKkELEHYKEkgeraeELENELHHLEKENELLQKKITNLKITCEK 657
Cdd:COG2433 387 EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVE-RLEAEVE------ELEAELEEKDERIERLERELSEARSEERR 459
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 1465187875 658 IEALEQENSELERENRKLKKtldsfknltfQLESLEKENSQLDEENLELRR 708
Cdd:COG2433 460 EIRKDREISRLDREIERLER----------ELEEERERIEELKRKLERLKE 500
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
779-872 |
9.68e-05 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 47.38 E-value: 9.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 779 IQQLESELQDLEMENQTLQKnlEELKISSKRLEQLEKENKSLEQETSQLekdKKQLEKENKRLRQQAEIKDtTLEENNVK 858
Cdd:COG0542 413 LDELERRLEQLEIEKEALKK--EQDEASFERLAELRDELAELEEELEAL---KARWEAEKELIEEIQELKE-ELEQRYGK 486
|
90
....*....|....
gi 1465187875 859 IGNLEKENKTLSKE 872
Cdd:COG0542 487 IPELEKELAELEEE 500
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
526-852 |
9.74e-05 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 47.64 E-value: 9.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 526 NLSKDLMKEKAQLEKTIETLRE------NSERQIKILEQE----NEHLNQTVSSLRQRSQIsaEARVKDIEKENKIL--- 592
Cdd:PRK04863 290 ELRRELYTSRRQLAAEQYRLVEmarelaELNEAESDLEQDyqaaSDHLNLVQTALRQQEKI--ERYQADLEELEERLeeq 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 593 -------HESIKETSSKLSKIEFEKRQIKKELEHYKEKGE----RAEELENELHHLEKENELLQKKITNLKITCEKIEAL 661
Cdd:PRK04863 368 nevveeaDEQQEENEARAEAAEEEVDELKSQLADYQQALDvqqtRAIQYQQAVQALERAKQLCGLPDLTADNAEDWLEEF 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 662 EQENSELERENRKLKKTLDSFKNLTFQLESL---------EKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELES 732
Cdd:PRK04863 448 QAKEQEATEELLSLEQKLSVAQAAHSQFEQAyqlvrkiagEVSRSEAWDVARELLRRLREQRHLAEQLQQLRMRLSELEQ 527
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 733 EKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN--------------KKIQQLESELQDLEM---ENQT 795
Cdd:PRK04863 528 RLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSesvsearerrmalrQQLEQLQARIQRLAArapAWLA 607
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1465187875 796 LQKNLEELK------------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:PRK04863 608 AQDALARLReqsgeefedsqdVTEYMQQLLERE-RELTVERDELAARKQALDEEIERLSQPGGSEDPRL 675
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-711 |
1.03e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.68 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 498 KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE----------NSERQIKILEQENEHLNQTV 567
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARriraleqelaALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 568 SSLRQR--SQISAEARVKDIEKENKILH-ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENElhhLEKENELL 644
Cdd:COG4942 100 EAQKEElaELLRALYRLGRQPPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE---LEAERAEL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1465187875 645 QKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEENLELRRNVE 711
Cdd:COG4942 177 EALLAELE---EERAALEALKAERQKLLARLEKELAELAA---ELAELQQEAEELEALIARLEAEAA 237
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
247-408 |
1.19e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.69 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsARMYRDELDALREKAVRVDKLE 326
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKE----------IKRLELEIEEVEARIKKYEEQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 327 SEVSRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL-HELEKENLQLKAKLHDMEMERDMDR 402
Cdd:COG1579 83 GNVRNNKEYealQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELeAELEEKKAELDEELAELEAELEELE 162
|
....*.
gi 1465187875 403 KKIEEL 408
Cdd:COG1579 163 AEREEL 168
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
478-1082 |
1.27e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.22 E-value: 1.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILEnEIVQEKQSLQncqnlskDLMKEKAQLEKTIETLR-ENSERQIKIL 556
Cdd:COG4913 222 DTFEAADALVEHFDDLERAHEALEDAREQIELLE-PIRELAERYA-------AARERLAELEYLRAALRlWFAQRRLELL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 557 EQENEHLNQTVSSLRQRSQIsAEARVKDIEKENKILHESIKEtsSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHH 636
Cdd:COG4913 294 EAELEELRAELARLEAELER-LEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLERELEERERRRARLEALLAA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 637 L-------EKENELLQKKITNLKITCEKI-EALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEENLELRR 708
Cdd:COG4913 371 LglplpasAEEFAALRAEAAALLEALEEElEALEEALAEAEAALRDLRRELRELEA---EIASLERRKSNIPARLLALRD 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 709 NVeslkCASMKMAQLQL----ENKELESEKEQLKKGLELLKASFKKT-------------------ERLEVSYQGL--DI 763
Cdd:COG4913 448 AL----AEALGLDEAELpfvgELIEVRPEEERWRGAIERVLGGFALTllvppehyaaalrwvnrlhLRGRLVYERVrtGL 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 764 ENQRLQKTLENS-NKKIQQLESELQD-LEMEnqtLQKNLEELKISSkrLEQLEKENKSLEQE------TSQLEKDKKQLE 835
Cdd:COG4913 524 PDPERPRLDPDSlAGKLDFKPHPFRAwLEAE---LGRRFDYVCVDS--PEELRRHPRAITRAgqvkgnGTRHEKDDRRRI 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 836 KENKRLRQQAEikdttleennVKIGNLEKENKTLSKEIGIYKEscvRLKELEKENKELVKRATiDIKTLVTLREDLVsek 915
Cdd:COG4913 599 RSRYVLGFDNR----------AKLAALEAELAELEEELAEAEE---RLEALEAELDALQERRE-ALQRLAEYSWDEI--- 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 916 lktqqmnnDLEKLTHELEKIGLNKERLlhdEQSTDDSRykllesklesTLKKSLEIKEEKIAALEARLEEstnynqqLRQ 995
Cdd:COG4913 662 --------DVASAEREIAELEAELERL---DASSDDLA----------ALEEQLEELEAELEELEEELDE-------LKG 713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 996 ELKTVKKNYEALKQRQDEERMVQSSPPISGEDnkWERESQETTRELLKVKDRLIEVERNnatLQAEKQALKTQLKQLETQ 1075
Cdd:COG4913 714 EIGRLEKELEQAEEELDELQDRLEAAEDLARL--ELRALLEERFAAALGDAVERELREN---LEERIDALRARLNRAEEE 788
|
....*..
gi 1465187875 1076 NNNLQAQ 1082
Cdd:COG4913 789 LERAMRA 795
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
601-786 |
1.49e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.30 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 601 SKLSKIEFEKRQIKKELEHYKEkgeRAEELENELHHLEKENELLQKKITNLKitcekiEALEQENSELERENRKLK--KT 678
Cdd:COG1579 17 SELDRLEHRLKELPAELAELED---ELAALEARLEAAKTELEDLEKEIKRLE------LEIEEVEARIKKYEEQLGnvRN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 679 LDSFKNLTFQLESLEKENSQLDEENLELRRNVEslkcasmkmaQLQLENKELESEKEQLKKGLELLKASfkkterlevsy 758
Cdd:COG1579 88 NKEYEALQKEIESLKRRISDLEDEILELMERIE----------ELEEELAELEAELAELEAELEEKKAE----------- 146
|
170 180
....*....|....*....|....*...
gi 1465187875 759 qgLDIENQRLQKTLENSNKKIQQLESEL 786
Cdd:COG1579 147 --LDEELAELEAELEELEAEREELAAKI 172
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
491-648 |
1.61e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.30 E-value: 1.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENserqikiLEQENEHLNQtVSSL 570
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEAR-------IKKYEEQLGN-VRNN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 571 RQRSQI-----SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK-GERAEELENELHHLEKENELL 644
Cdd:COG1579 89 KEYEALqkeieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAElDEELAELEAELEELEAEREEL 168
|
....
gi 1465187875 645 QKKI 648
Cdd:COG1579 169 AAKI 172
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
257-586 |
1.68e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 46.66 E-value: 1.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 257 KAKIRRLRQELEEKTEQlLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRD-ELDALREKAvrvDKLESEVSRYKER 335
Cdd:pfam17380 295 KMEQERLRQEKEEKARE-VERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERErELERIRQEE---RKRELERIRQEEI 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 336 LHDIEfykaRVEELKEDNQVLLETKTMLEDQLEGtrARSDKLHELEKenlQLKAKLHDMEMERdmDRKKIEELMEENMTL 415
Cdd:pfam17380 371 AMEIS----RMRELERLQMERQQKNERVRQELEA--ARKVKILEEER---QRKIQQQKVEMEQ--IRAEQEEARQREVRR 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 416 EMAQKQSmdeslhlgwELEQIsRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD-SVEGNASKIL 494
Cdd:pfam17380 440 LEEERAR---------EMERV-RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEkELEERKQAMI 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDL-MKEKAQLEKTIETLRENSERqIKILEQENEHLNQTVSSLRQR 573
Cdd:pfam17380 510 EEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQeMEERRRIQEQMRKATEERSR-LEAMEREREMMRQIVESEKAR 588
|
330
....*....|...
gi 1465187875 574 SQISAEARVKDIE 586
Cdd:pfam17380 589 AEYEATTPITTIK 601
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
656-898 |
1.69e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 45.67 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 656 EKIEALEQENSELERENRKLKKTLDSFKNLTFQL-ESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Cdd:COG1340 8 SSLEELEEKIEELREEIEELKEKRDELNEELKELaEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN----------KKIQQLESELQDLEME---NQTLQKNLE 801
Cdd:COG1340 88 NELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVlspeeekelvEKIKELEKELEKAKKAlekNEKLKELRA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEScv 881
Cdd:COG1340 168 ELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKE-- 245
|
250
....*....|....*..
gi 1465187875 882 rLKELEKENKELVKRAT 898
Cdd:COG1340 246 -LKKLRKKQRALKREKE 261
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1184-1376 |
1.84e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 46.47 E-value: 1.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1184 LKSAHKNLEvehRdLEDRYNQLLKQKGQL----EDLEKMLKVEQEKMLLEnknHETVAAEYKKLCGENDRLNHTYSQLLK 1259
Cdd:COG1196 181 LEATEENLE---R-LEDILGELERQLEPLerqaEKAERYRELKEELKELE---AELLLLKLRELEAELEELEAELEELEA 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1260 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNR 1339
Cdd:COG1196 254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333
|
170 180 190
....*....|....*....|....*....|....*..
gi 1465187875 1340 TLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEK 1376
Cdd:COG1196 334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
638-940 |
1.85e-04 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 46.75 E-value: 1.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 638 EKENELLQKKITNLKIT----CEKIEALEQENSELERENRKLKKTLDSFKNLTFQL-----ESLEKENSQLDEENLELRR 708
Cdd:PRK00448 1 NEMQEKFKKLLDQINIPddlqSEALESAEIEKVVVDKKSKKWEFHLKFPNILPIEDfklfkEKLKQSFSHIADIKVTFSI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 709 NVESLKCasmkmaQLQLENKELESEKEQLKKGLELLKASFKKTE------RLEVSYQGlDIENQRL-QKTLENSNKKIQQ 781
Cdd:PRK00448 81 EVENITF------TEELLLDYWNEIIEKAKKNSPLFKSLLKKQKvevegnKLIIKVNN-EIERDHLkKKHLPKLIKQYEK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 782 LESELqdLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK---------RLRQQAEI---KD 849
Cdd:PRK00448 154 FGFGI--LKIDFEIDDSKEELEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDpkegpvqigKKIDKEEItpmKE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 850 TTLEENNVKI-G--------NLEKENKTLSKEIGIYKEScVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL-KTQ 919
Cdd:PRK00448 232 INEEERRVVVeGyvfkveikELKSGRHILTFKITDYTSS-IIVKKFSRDKEDLKKFDEIKKGDWVKVRGSVQNDTFtRDL 310
|
330 340
....*....|....*....|..
gi 1465187875 920 QMN-NDLEKLTHELEKIGLNKE 940
Cdd:PRK00448 311 VMNaQDINEIKHPERKDTAEEE 332
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
706-896 |
2.10e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.92 E-value: 2.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 706 LRRNVESLKCASMK-MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEvsyQGLDIENQRLQKTLENSNKKIQQLES 784
Cdd:PRK12704 24 VRKKIAEAKIKEAEeEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFE---KELRERRNELQKLEKRLLQKEENLDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 785 ELQDLEmenqtlqknleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE-IKDTTLEE-NNVKIGNL 862
Cdd:PRK12704 101 KLELLE-----------------KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELErISGLTAEEaKEILLEKV 163
|
170 180 190
....*....|....*....|....*....|....
gi 1465187875 863 EKENKTlskeigiykESCVRLKELEKENKELVKR 896
Cdd:PRK12704 164 EEEARH---------EAAVLIKEIEEEAKEEADK 188
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
772-1365 |
2.55e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 46.06 E-value: 2.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 772 LENSNKKIQQLESELQDLE--MENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ-AEIK 848
Cdd:COG4913 257 IRELAERYAAARERLAELEylRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQiRGNG 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 849 DTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVT--------LREDLVSEKLKTQQ 920
Cdd:COG4913 337 GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEaleeeleaLEEALAEAEAALRD 416
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 921 MNNDLEKLTHELEKIGLNKerllhdeqSTDDSRYKLLESKLESTLKKS----------LEIKEEKIA---ALE------- 980
Cdd:COG4913 417 LRRELRELEAEIASLERRK--------SNIPARLLALRDALAEALGLDeaelpfvgelIEVRPEEERwrgAIErvlggfa 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 981 -------ARLEESTNY--NQQLRQELktvkkNYEALKQRQDEERMVQSSP-----PISGEDNKWeresQETTRELLKVKD 1046
Cdd:COG4913 489 ltllvppEHYAAALRWvnRLHLRGRL-----VYERVRTGLPDPERPRLDPdslagKLDFKPHPF----RAWLEAELGRRF 559
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1047 RLIEVErNNATLQAEKQALkT---QLKQLET-----------------QNNnlQAQILALQRQTVSLQEQNTTLQTQNAK 1106
Cdd:COG4913 560 DYVCVD-SPEELRRHPRAI-TragQVKGNGTrhekddrrrirsryvlgFDN--RAKLAALEAELAELEEELAEAEERLEA 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1107 LQVENSTLNSQSTSLmnqnaQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLhERQASEyesliskhgtlks 1186
Cdd:COG4913 636 LEAELDALQERREAL-----QRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAAL-EEQLEE------------- 696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1187 ahknLEVEHRDLEDRYNQLLKQKGQLEDlekmlKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKET----- 1261
Cdd:COG4913 697 ----LEAELEELEEELDELKGEIGRLEK-----ELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAverel 767
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1262 -EVLQTDHKNLKSLLNNsklEQTRLEAEFSKLKEQY----QQLDITSTKLNNQCELLSQLKGN-LEEENRHLLDQIQTLM 1335
Cdd:COG4913 768 rENLEERIDALRARLNR---AEEELERAMRAFNREWpaetADLDADLESLPEYLALLDRLEEDgLPEYEERFKELLNENS 844
|
650 660 670
....*....|....*....|....*....|
gi 1465187875 1336 LQNRTLLEQNMESkDLFHVEQRqyIDKLNE 1365
Cdd:COG4913 845 IEFVADLLSKLRR-AIREIKER--IDPLND 871
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
247-422 |
2.63e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.59 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSAR-MYRDELDALREKAVRVDKL 325
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReELGERARALYRSGGSVSYL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 326 E-----SEVSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL----HELEKENLQLKAKLH 392
Cdd:COG3883 106 DvllgsESFSDFLDRLSALskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELeaakAELEAQQAEQEALLA 185
|
170 180 190
....*....|....*....|....*....|
gi 1465187875 393 DMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Cdd:COG3883 186 QLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
240-573 |
2.92e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.10 E-value: 2.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 240 MKRTESRQHLSVELADAkakirrlRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSArmyRDELdALREKA 319
Cdd:COG3096 274 MRHANERRELSERALEL-------RRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAA---SDHL-NLVQTA 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 320 VRvdkLESEVSRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERD 399
Cdd:COG3096 343 LR---QQEKIERYQEDLEELT------ERLEEQEEVVEE----AAEQLAEAEAR---LEAAEEEVDSLKSQLADYQQALD 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 400 MDRKKIEELMEENMTLEMAQKQSMDESLHlgweLEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEEL 479
Cdd:COG3096 407 VQQTRAIQYQQAVQALEKARALCGLPDLT----PENAEDYLAAFRAKEQQATEEVLEL-EQKLSVADAARRQFEKAYELV 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 480 RTTVDSVE-----GNASKILKMEKENQRLSKKVEILE---NEIVQEKQSLQNCQNLSKDLMK--------------EKAQ 537
Cdd:COG3096 482 CKIAGEVErsqawQTARELLRRYRSQQALAQRLQQLRaqlAELEQRLRQQQNAERLLEEFCQrigqqldaaeeleeLLAE 561
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 1465187875 538 LEKTIETL----RENSERQIKiLEQENEHLNQTVSSLRQR 573
Cdd:COG3096 562 LEAQLEELeeqaAEAVEQRSE-LRQQLEQLRARIKELAAR 600
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
592-1000 |
3.07e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 45.66 E-value: 3.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 592 LHESIKETSSKLSKIEFEKRQIKKELEHYKEKgerAEELENELHHLEKENELLQkkiTNLKITCEKIEALEQENSELERE 671
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRD---REQWERQRRELESRVAELK---EELRQSREKHEELEEKYKELSAS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 672 NrklkktldsfknltfqlESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENK-ELESEKEQLKKGLELLKASFKK 750
Cdd:pfam07888 110 S-----------------EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLEREtELERMKERAKKAGAQRKEEEAE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 751 TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Cdd:pfam07888 173 RKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 831 KKQLEKEnkrLRQQAEIKDTTLEEnnvkignLEKENKTLSKEIGIYKESCVRLKE----LEKENKELVKRATIDIKTLVT 906
Cdd:pfam07888 253 VEGLGEE---LSSMAAQRDRTQAE-------LHQARLQAAQLTLQLADASLALREgrarWAQERETLQQSAEADKDRIEK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 907 LREDLVSEKLKTQQMNNDLEKLTHELekiglnkerllhdEQSTDDSRYKLLESKLEST-LKKSLEIKEEKIAALEARLEE 985
Cdd:pfam07888 323 LSAELQRLEERLQEERMEREKLEVEL-------------GREKDCNRVQLSESRRELQeLKASLRVAQKEKEQLQAEKQE 389
|
410
....*....|....*
gi 1465187875 986 STNYNQQLRQELKTV 1000
Cdd:pfam07888 390 LLEYIRQLEQRLETV 404
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
722-873 |
3.13e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 3.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEME----NQTLQ 797
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREElgerARALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 798 KN------LEEL-----------------KISS---KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT 851
Cdd:COG3883 97 RSggsvsyLDVLlgsesfsdfldrlsalsKIADadaDLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176
|
170 180
....*....|....*....|..
gi 1465187875 852 LEENNVKIGNLEKENKTLSKEI 873
Cdd:COG3883 177 QAEQEALLAQLSAEEAAAEAQL 198
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
596-826 |
3.44e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 3.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 596 IKETSSKLSKIEFEKRQIKKELehyKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQE----NSELERE 671
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAEL---DALQAELEELNEEYNELQAELEALQAEIDKLQ---AEIAEAEAEieerREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 672 NRKLKKTLDSFKNLTFQLESlekensqldeENL-ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLEllkasfKK 750
Cdd:COG3883 92 ARALYRSGGSVSYLDVLLGS----------ESFsDFLDRLSALSKIADADADLLEELKADKAELEAKKAELE------AK 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1465187875 751 TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:COG3883 156 LAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
639-935 |
3.53e-04 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 44.56 E-value: 3.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEEN---LELRRNVESLkc 715
Cdd:pfam09728 1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKK---KQDQLQKEKDQLQSELskaILAKSKLEKL-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 716 asmkMAQLQLENKELESEKEQLKKGLE----LLKASFKKTeRLEVSYQGLDIENQRLQKTLENSN--KKIQQL--ESELQ 787
Cdd:pfam09728 76 ----CRELQKQNKKLKEESKKLAKEEEekrkELSEKFQST-LKDIQDKMEEKSEKNNKLREENEElrEKLKSLieQYELR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 788 DLEMENQTLQKNLE----ELKISSKRLEQlEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIK-------DTTLEEN 855
Cdd:pfam09728 151 ELHFEKLLKTKELEvqlaEAKLQQATEEE-EKKAQEKEVAKARELKAQvQTLSETEKELREQLNLYvekfeefQDTLNKS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 856 NVKIGNLEKENKTLSKEIgiykescvrlKELEKENKELVKRATIDIKTLVtlreDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:pfam09728 230 NEVFTTFKKEMEKMSKKI----------KKLEKENLTWKRKWEKSNKALL----EMAEERQKLKEELEKLQKKLEKLENL 295
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1198-1377 |
4.44e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 4.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1198 LEDRYNQLLKQKG--------QLEDLEKMLKVEQEKMllenknhetvaAEYKKLCGENDRLNHTYSQLLKETEVLQTDHK 1269
Cdd:COG4717 51 LEKEADELFKPQGrkpelnlkELKELEEELKEAEEKE-----------EEYAELQEELEELEEELEELEAELEELREELE 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1270 NLKSLLNNSKLEQTR--LEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNME 1347
Cdd:COG4717 120 KLEKLLQLLPLYQELeaLEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAE 199
|
170 180 190
....*....|....*....|....*....|
gi 1465187875 1348 SKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1377
Cdd:COG4717 200 ELEELQQRLAELEEELEEAQEELEELEEEL 229
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
420-677 |
4.56e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 45.13 E-value: 4.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 420 KQSMDESLHLGWELEQISRTSElsEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKE 499
Cdd:pfam09731 167 KEASDTAEISREKATDSALQKA--EALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 500 NQRLSKKVEILENEIVQEKQSLQN--CQNLSKDLMKEKA--------------QLEKTIETLRENSERQI-KILEQENEH 562
Cdd:pfam09731 245 VDQYKELVASERIVFQQELVSIFPdiIPVLKEDNLLSNDdlnsliahahreidQLSKKLAELKKREEKHIeRALEKQKEE 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 563 LNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH-----HL 637
Cdd:pfam09731 325 LDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAEAHEEHLKDVLVEQEIELQREFLqdikeKV 404
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1465187875 638 EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKK 677
Cdd:pfam09731 405 EEERAGRLLKLNELLANLKGLEKATSSHSEVEDENRKAQQ 444
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
759-896 |
4.79e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 4.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 759 QGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL--------------------EKENK 818
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEieevearikkyeeqlgnvrnNKEYE 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1465187875 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI-GIYKESCVRLKELEKENKELVKR 896
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELdEELAELEAELEELEAEREELAAK 171
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
240-668 |
4.91e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 45.33 E-value: 4.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 240 MKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnlLSDArsarmyRDELDALREKA 319
Cdd:PRK04863 275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQD----YQAA------SDHLNLVQTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 320 VRVDKLEsevsRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARSDklhELEKENLQLKAKLHDMEMERD 399
Cdd:PRK04863 345 RQQEKIE----RYQADLEELE------ERLEEQNEVVEE----ADEQQEENEARAE---AAEEEVDELKSQLADYQQALD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 400 MDRKKIEELMEENMTLEMAQKQSMDESLhlgwELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEEL 479
Cdd:PRK04863 408 VQQTRAIQYQQAVQALERAKQLCGLPDL----TADNAEDWLEEFQAKEQEATEELLSL-EQKLSVAQAAHSQFEQAYQLV 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 480 RTTVDSVEGN-----ASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK 554
Cdd:PRK04863 483 RKIAGEVSRSeawdvARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEE 562
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 555 iLEQENEHLNQTVSSLRQRSqisaeARVKDIEKENKILHEsiketssKLSKIEFEKRQIKKEL----EHYKEKGERAEEL 630
Cdd:PRK04863 563 -LEARLESLSESVSEARERR-----MALRQQLEQLQARIQ-------RLAARAPAWLAAQDALarlrEQSGEEFEDSQDV 629
|
410 420 430
....*....|....*....|....*....|....*....
gi 1465187875 631 ENEL-HHLEKENELLQKKITnlkiTCEKIEALEQENSEL 668
Cdd:PRK04863 630 TEYMqQLLERERELTVERDE----LAARKQALDEEIERL 664
|
|
| Uso1_p115_C |
pfam04871 |
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular ... |
777-873 |
5.39e-04 |
|
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerization, and a short C-terminal acidic region. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the golgi stack. This family consists of the acidic C-terminus, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another.
Pssm-ID: 461461 [Multi-domain] Cd Length: 121 Bit Score: 41.62 E-value: 5.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Cdd:pfam04871 1 AKKSELESEASSLKNENTELKAELQELSKQYNSLEQKESQAKELEAEVKKLEEALKKLKAELSEEKQKEKEKQSELDDLL 80
|
90
....*....|....*..
gi 1465187875 857 VKIGNLEKENKTLSKEI 873
Cdd:pfam04871 81 LLLGDLEEKVEKYKARL 97
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
343-572 |
5.39e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.62 E-value: 5.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdmemerdmdRKKIEELMEENMTLEMAQKQS 422
Cdd:PHA02562 173 KDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARK-------------QNKYDELVEEAKTIKAEIEEL 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 423 MDESLHLgwELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEK---- 498
Cdd:PHA02562 240 TDELLNL--VMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHslek 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 499 -------------ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTietlRENSERQIKILEQENEHLNQ 565
Cdd:PHA02562 318 ldtaideleeimdEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAE----FVDNAEELAKLQDELDKIVK 393
|
....*..
gi 1465187875 566 TVSSLRQ 572
Cdd:PHA02562 394 TKSELVK 400
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
652-895 |
6.23e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.62 E-value: 6.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQldeenlELRRNVESLKCasmKMAQLQLENKELE 731
Cdd:PHA02562 170 KLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIA------RKQNKYDELVE---EAKTIKAEIEELT 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 732 SEKEQLKKGLELLKASFKKterlevsyqgLDIENQRLQKTLENSNKKIQQLESE------LQDLEMENQTLQKNLEELKI 805
Cdd:PHA02562 241 DELLNLVMDIEDPSAALNK----------LNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITKIKDKLKE 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 806 SSKRLEQLEKEnkslEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEScvrLKE 885
Cdd:PHA02562 311 LQHSLEKLDTA----IDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEE---LAK 383
|
250
....*....|
gi 1465187875 886 LEKENKELVK 895
Cdd:PHA02562 384 LQDELDKIVK 393
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
579-750 |
6.35e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.37 E-value: 6.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 579 EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKItcekI 658
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE----Y 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 659 EALEQENSELERENRKLKKTLdsfKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLK 738
Cdd:COG1579 92 EALQKEIESLKRRISDLEDEI---LELMERIEELEEELAELEAELAELEAELEEKK------AELDEELAELEAELEELE 162
|
170
....*....|..
gi 1465187875 739 KGLELLKASFKK 750
Cdd:COG1579 163 AEREELAAKIPP 174
|
|
| DUF3498 |
pfam12004 |
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. ... |
801-850 |
6.35e-04 |
|
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 433 to 538 amino acids in length. This domain is found associated with pfam00616, pfam00168. This domain has two conserved sequence motifs: DLQ and PLSFQNP.
Pssm-ID: 463427 [Multi-domain] Cd Length: 511 Bit Score: 44.36 E-value: 6.35e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 1465187875 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQ-LEKENKRLRQQAEIKDT 850
Cdd:pfam12004 399 ERLRVSNRKLEEYERRLLAQEEQTQKLLLEYQArLEDSEERLRRQQEEKDS 449
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
719-896 |
6.87e-04 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 42.61 E-value: 6.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 719 KMAQLQLENKELESEKEQLKKGLELLKASfkKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQK 798
Cdd:pfam08614 15 RTALLEAENAKLQSEPESVLPSTSSSKLS--KASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEK 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 799 NLEElkiSSKRLEQLEKENKSLEQEtsqlekdKKQLEKENKRLRQQAEIkdttleennvkignLEKENKTLSKEIGIYKE 878
Cdd:pfam08614 93 KLRE---DERRLAALEAERAQLEEK-------LKDREEELREKRKLNQD--------------LQDELVALQLQLNMAEE 148
|
170
....*....|....*...
gi 1465187875 879 scvRLKELEKENKELVKR 896
Cdd:pfam08614 149 ---KLRKLEKENRELVER 163
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
825-1213 |
8.04e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 8.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 825 SQLEKDKKQLEKENKRLRqqaEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATiDIKTL 904
Cdd:COG4717 49 ERLEKEADELFKPQGRKP---ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-KLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKErlLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLE 984
Cdd:COG4717 125 LQLLPLYQELEALEAELAELPERLEELEERLEELRE--LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 985 ESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWER-------------------------------- 1032
Cdd:COG4717 203 ELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallallglggsllsliltiagvlflv 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1033 ------ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAK 1106
Cdd:COG4717 283 lgllalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEE 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1107 LQVEnstlnsqstSLMNQNAQLLIQQSSlenENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHG--TL 1184
Cdd:COG4717 363 LQLE---------ELEQEIAALLAEAGV---EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDeeEL 430
|
410 420
....*....|....*....|....*....
gi 1465187875 1185 KSAHKNLEVEHRDLEDRYNQLLKQKGQLE 1213
Cdd:COG4717 431 EEELEELEEELEELEEELEELREELAELE 459
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
960-1170 |
8.90e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 44.27 E-value: 8.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 960 KLESTLKKSLEIKEEKIAALEARLEeSTNYNQQLRQELKTVKKNYEALKQRQDEERMvqssppISGEDNKWERESQETTR 1039
Cdd:PRK10929 79 KLSAELRQQLNNERDEPRSVPPNMS-TDALEQEILQVSSQLLEKSRQAQQEQDRARE------ISDSLSQLPQQQTEARR 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1040 ELLKVKDRL--------IEVERNNATLQAEKQALKTQLKQLETqnnnlqAQILALQRQTVS------LQEQNTTLqtqNA 1105
Cdd:PRK10929 152 QLNEIERRLqtlgtpntPLAQAQLTALQAESAALKALVDELEL------AQLSANNRQELArlrselAKKRSQQL---DA 222
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1106 KLQVENSTLNSQStslmNQNAQLLIQQSSLENEN-----ESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1170
Cdd:PRK10929 223 YLQALRNQLNSQR----QREAERALESTELLAEQsgdlpKSIVAQFKINRELSQALNQQAQRMDLIASQQ 288
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
975-1383 |
1.01e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 44.06 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 975 KIAALEARLEEStnYNQQLRQELKTVKKnyealkqrqdeermvqssPPISGED----NKWERESQE-TTRELLKVKDRLI 1049
Cdd:PRK04778 30 RIDELEERKQEL--ENLPVNDELEKVKK------------------LNLTGQSeekfEEWRQKWDEiVTNSLPDIEEQLF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1050 EVERNNAT--LQAEKQALKT---QLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQvenSTLNSQSTS---- 1120
Cdd:PRK04778 90 EAEELNDKfrFRKAKHEINEiesLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELR---KSLLANRFSfgpa 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1121 ---LMNQNAQLLIQQSSLENENES--VIKEREDLKSLYDSLI---KDHEKLELLHERQASEYESLISKhgtLKSAHKNLE 1192
Cdd:PRK04778 167 ldeLEKQLENLEEEFSQFVELTESgdYVEAREILDQLEEELAaleQIMEEIPELLKELQTELPDQLQE---LKAGYRELV 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1193 VEHRDLEDrynqlLKQKGQLEDLEKmlKVEQEKMLLENKNHETVAAEYKKLcgeNDRLNHTYSQLLKETE---VLQTDHK 1269
Cdd:PRK04778 244 EEGYHLDH-----LDIEKEIQDLKE--QIDENLALLEELDLDEAEEKNEEI---QERIDQLYDILEREVKarkYVEKNSD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1270 NLKSLLNNSKLEQTRLEAEFSKLKEQYQqldITSTKLNNQCELLSQLKgNLEEENRHLLDQI--QTL---MLQNRtlLEQ 1344
Cdd:PRK04778 314 TLPDFLEHAKEQNKELKEEIDRVKQSYT---LNESELESVRQLEKQLE-SLEKQYDEITERIaeQEIaysELQEE--LEE 387
|
410 420 430
....*....|....*....|....*....|....*....
gi 1465187875 1345 NMESKDLFHVEQRQYIDKLNELRRQKEKLEEKImDQYKF 1383
Cdd:PRK04778 388 ILKQLEEIEKEQEKLSEMLQGLRKDELEAREKL-ERYRN 425
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
495-809 |
1.06e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 44.12 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 495 KMEKENQRLSKKVEIL--------ENEIVQEKQSLQNCQNLSKdLMKEKAQLEKTIETLREN---SERQIKILEQENEHL 563
Cdd:PLN02939 118 NSKDGEQLSDFQLEDLvgmiqnaeKNILLLNQARLQALEDLEK-ILTEKEALQGKINILEMRlseTDARIKLAAQEKIHV 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 564 NQTVSSLRQ-RSQISAEarvkdIEKENKILHESIKEtsskLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENE 642
Cdd:PLN02939 197 EILEEQLEKlRNELLIR-----GATEGLCVHSLSKE----LDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERS 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 643 LLqkkitnlkitcekiealeqENSELERENRKLKKTLDSFKNLTFQLESL-EKensqldEENLELRrnVESLKCASMKMA 721
Cdd:PLN02939 268 LL-------------------DASLRELESKFIVAQEDVSKLSPLQYDCWwEK------VENLQDL--LDRATNQVEKAA 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDlemenqtLQKNLE 801
Cdd:PLN02939 321 LVLDQNQDLRDKVDKLEASLKEANVSKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKE-------FQDTLS 393
|
....*...
gi 1465187875 802 ELKISSKR 809
Cdd:PLN02939 394 KLKEESKK 401
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
792-843 |
1.11e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 43.67 E-value: 1.11e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 792 ENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:PRK03992 2 RLEALEERNSELE---EQIRQLELKLRDLEAENEKLERELERLKSELEKLKS 50
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
490-711 |
1.13e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 43.69 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 490 ASKIL-KMEKENQRLSKKVEILENEIVQEKQS----LQNCQNLSKDLMKEK-----AQLEKTIETLRENSERQIKIL--- 556
Cdd:pfam06160 177 AREVLeKLEEETDALEELMEDIPPLYEELKTElpdqLEELKEGYREMEEEGyalehLNVDKEIQQLEEQLEENLALLenl 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 557 -----EQENEHLNQTVSSLrqrsqisaearVKDIEKE---NKILHESIKETSSKLSKIEFEKRQIKKELEHYK------- 621
Cdd:pfam06160 257 eldeaEEALEEIEERIDQL-----------YDLLEKEvdaKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQqsytlne 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 622 EKGERAEELENELHHLEKENELLQKKITNLKIT----CEKIEALEQENSELERENRKLKKTLDSfknltfqLESLEKEN- 696
Cdd:pfam06160 326 NELERVRGLEKQLEELEKRYDEIVERLEEKEVAyselQEELEEILEQLEEIEEEQEEFKESLQS-------LRKDELEAr 398
|
250
....*....|....*...
gi 1465187875 697 ---SQLDEENLELRRNVE 711
Cdd:pfam06160 399 eklDEFKLELREIKRLVE 416
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
434-690 |
1.30e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 43.76 E-value: 1.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 434 EQISRTSELSEAPQKsLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgnaSKILKMEKENQRLSKKVEILEne 513
Cdd:PRK05771 47 KLRSLLTKLSEALDK-LRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIE---KEIKELEEEISELENEIKELE-- 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 514 ivQEKQSLQNCQNLSKDLmkEKAQLEKTIE----TLRENSERQIKILEQENEHLnqTVSSLRQRSQISAEARVKDIEKEN 589
Cdd:PRK05771 121 --QEIERLEPWGNFDLDL--SLLLGFKYVSvfvgTVPEDKLEELKLESDVENVE--YISTDKGYVYVVVVVLKELSDEVE 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 590 KILhesiketssklSKIEFEKRQIKKE---LEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEkiEALEQens 666
Cdd:PRK05771 195 EEL-----------KKLGFERLELEEEgtpSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALY--EYLEI--- 258
|
250 260
....*....|....*....|....*.
gi 1465187875 667 ELEREN--RKLKKTldsfkNLTFQLE 690
Cdd:PRK05771 259 ELERAEalSKFLKT-----DKTFAIE 279
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
498-1009 |
1.35e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 43.66 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 498 KENQRLSKKVEILENEIVQEKQSLQ-------------NCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Cdd:pfam10174 130 KELFLLRKTLEEMELRIETQKQTLGardesikkllemlQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENI 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 565 QTVSSLRQRSQISAEArvkdieKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGeraeelenELHHLEKENELL 644
Cdd:pfam10174 210 HLREELHRRNQLQPDP------AKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNG--------LLHTEDREEEIK 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 645 QKKI--TNLKITCEKIEALEQENSELERENRKLKKTLDSFKN-----------LTFQLESLEKENSQLDEENLELRRNVE 711
Cdd:pfam10174 276 QMEVykSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNqnsdckqhievLKESLTAKEQRAAILQTEVDALRLRLE 355
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 712 S----LKCASMKMAQLQLENKELESEKEQLKKGLELLKASF----KKTERL-------EVSYQGLDIENQRLQKTLENSN 776
Cdd:pfam10174 356 EkesfLNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKInvlqKKIENLqeqlrdkDKQLAGLKERVKSLQTDSSNTD 435
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 777 KKIQQLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQA---------- 845
Cdd:pfam10174 436 TALTTLEEALSEKERIIERLKEQRErEDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHAsslassglkk 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 846 -------EIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKE---NKELVKRATIDIKTLVTLREDLVSEK 915
Cdd:pfam10174 516 dsklkslEIAVEQKKEECSKLENQLKKAHNAEEAVRTNPEINDRIRLLEQEvarYKEESGKAQAEVERLLGILREVENEK 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 916 lktqqmnNDLEKLTHELEKIGLNKerllHDEQSTDDSRYKLLE----SKLESTLKKSLEIKEEKIA-ALEARLEESTNYN 990
Cdd:pfam10174 596 -------NDKDKKIAELESLTLRQ----MKEQNKKVANIKHGQqemkKKGAQLLEEARRREDNLADnSQQLQLEELMGAL 664
|
570
....*....|....*....
gi 1465187875 991 QQLRQELKTVKKNYEALKQ 1009
Cdd:pfam10174 665 EKTRQELDATKARLSSTQQ 683
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
571-846 |
1.70e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 1.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 571 RQRSQISAE-ARVKDIEKENKILHESIKETSSKLSKIE-----FEKRQIKKELEHYKEKGERAEELENELHHLEKENELL 644
Cdd:COG3096 843 QRRSELERElAQHRAQEQQLRQQLDQLKEQLQLLNKLLpqanlLADETLADRLEELREELDAAQEAQAFIQQHGKALAQL 922
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 645 QKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS-QLDEENLELrrnVESLKcasmkmAQL 723
Cdd:COG3096 923 EPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAvGLLGENSDL---NEKLR------ARL 993
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 724 QLENKELESEKEQLKKglellkasfkKTERLEVSYQGLdienQRLQKTLENSNKKIQQLESELQDL------EMENQTLQ 797
Cdd:COG3096 994 EQAEEARREAREQLRQ----------AQAQYSQYNQVL----ASLKSSRDAKQQTLQELEQELEELgvqadaEAEERARI 1059
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1465187875 798 KNLE---ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG3096 1060 RRDElheELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVV 1111
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
252-351 |
1.73e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.31 E-value: 1.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdARSARMYRDELDALREkavRVDKLESEVSR 331
Cdd:COG2433 414 EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE-------ERREIRKDREISRLDR---EIERLERELEE 483
|
90 100
....*....|....*....|
gi 1465187875 332 YKERLHDIefyKARVEELKE 351
Cdd:COG2433 484 ERERIEEL---KRKLERLKE 500
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
1036-1114 |
1.77e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 41.07 E-value: 1.77e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1465187875 1036 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Cdd:pfam08614 82 DLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEKLRKLEKENREL 160
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
734-1073 |
1.80e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.97 E-value: 1.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLemeNQTLQKNLEELKISSKRLEQL 813
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL---NEQLQAAQAELAQAQEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLK--ELEKENK 891
Cdd:COG4372 107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSeaEAEQALD 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 892 ELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEI 971
Cdd:COG4372 187 ELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELA 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 972 KEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEV 1051
Cdd:COG4372 267 ILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLL 346
|
330 340
....*....|....*....|..
gi 1465187875 1052 ERNNATLQAEKQALKTQLKQLE 1073
Cdd:COG4372 347 LVGLLDNDVLELLSKGAEAGVA 368
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
945-1110 |
1.90e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.08 E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 945 DEQSTDDSRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTN---------YNQQLRQELKTVKKNYEALKQRQDEE- 1014
Cdd:COG3206 212 EEAKLLLQQLSELESQL-AEARAELAEAEARLAALRAQLGSGPDalpellqspVIQQLRAQLAELEAELAELSARYTPNh 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1015 -RMVQssppisgednkwERESQETTRELLK--VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL---QAQILALQR 1088
Cdd:COG3206 291 pDVIA------------LRAQIAALRAQLQqeAQRILASLEAELEALQAREASLQAQLAQLEARLAELpelEAELRRLER 358
|
170 180
....*....|....*....|..
gi 1465187875 1089 QTVSLQEQNTTLQTQNAKLQVE 1110
Cdd:COG3206 359 EVEVARELYESLLQRLEEARLA 380
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
255-741 |
1.97e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.11 E-value: 1.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 255 DAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMN--------LLSDARSARMYRDELDALREKAVRVDKLE 326
Cdd:TIGR00606 636 DEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSccpvcqrvFQTEAELQEFISDLQSKLRLAPDKLKSTE 715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 327 SEVSRyKERLHDIEFYKARVEElKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDM--DRKK 404
Cdd:TIGR00606 716 SELKK-KEKRRDEMLGLAPGRQ-SIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCltDVTI 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 405 IEELMEENMTLE--MAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVnELTSSRLLKLEMENQSLTKTVEELRTT 482
Cdd:TIGR00606 794 MERFQMELKDVErkIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKI-ELNRKLIQDQQEQIQHLKSKTNELKSE 872
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 483 VDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEH 562
Cdd:TIGR00606 873 KLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKN 952
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 563 LNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE------LENELHH 636
Cdd:TIGR00606 953 IHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDnltlrkRENELKE 1032
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 637 LEKENELLQKKITNLKITCEKIEALEQENsELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLElrrnvESLKCA 716
Cdd:TIGR00606 1033 VEEELKQHLKEMGQMQVLQMKQEHQKLEE-NIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAE-----EKYREM 1106
|
490 500
....*....|....*....|....*
gi 1465187875 717 SMKMAQLQLENKELESEKEQLKKGL 741
Cdd:TIGR00606 1107 MIVMRTTELVNKDLDIYYKTLDQAI 1131
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
839-1015 |
1.98e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.83 E-value: 1.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 839 KRLRQQAEIkDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKT 918
Cdd:COG1579 7 RALLDLQEL-DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKY-EEQLGN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 919 QQMNNDLEKLTHELEKIGLNKERLlhdeqstddsRYKLLEsklestLKKSLEIKEEKIAALEARLEESTNYNQQLRQELK 998
Cdd:COG1579 85 VRNNKEYEALQKEIESLKRRISDL----------EDEILE------LMERIEELEEELAELEAELAELEAELEEKKAELD 148
|
170
....*....|....*..
gi 1465187875 999 TVKKNYEALKQRQDEER 1015
Cdd:COG1579 149 EELAELEAELEELEAER 165
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
507-769 |
2.19e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 42.99 E-value: 2.19e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 507 VEIleNEIVQEKQSLQNcQNLSKDLMKekaqLEKTIETLRENSERQIKILEQENEhlnQTVSSLRQRSQiSAEARVKDIE 586
Cdd:PRK05771 31 VHI--EDLKEELSNERL-RKLRSLLTK----LSEALDKLRSYLPKLNPLREEKKK---VSVKSLEELIK-DVEEELEKIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 587 KENKILHESIKETSSKLSKIEFEKRQIKKelehykekgeraeeleneLHHLEKENELLQKKiTNLKITCEKIEALEQENS 666
Cdd:PRK05771 100 KEIKELEEEISELENEIKELEQEIERLEP------------------WGNFDLDLSLLLGF-KYVSVFVGTVPEDKLEEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 667 ELERENRKLkKTLDSFKNLTF--------QLESLEKENSQLDEENLELrrnvESLKCASMKMAQLQLENKELESEKEQLK 738
Cdd:PRK05771 161 KLESDVENV-EYISTDKGYVYvvvvvlkeLSDEVEEELKKLGFERLEL----EEEGTPSELIREIKEELEEIEKERESLL 235
|
250 260 270
....*....|....*....|....*....|..
gi 1465187875 739 KGLELLKasfKKTERLEVSYQG-LDIENQRLQ 769
Cdd:PRK05771 236 EELKELA---KKYLEELLALYEyLEIELERAE 264
|
|
| Prefoldin_2 |
pfam01920 |
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996. |
777-854 |
2.43e-03 |
|
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996.
Pssm-ID: 396482 [Multi-domain] Cd Length: 102 Bit Score: 39.13 E-value: 2.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK------------SLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam01920 2 NKFQQLQQQLQLLAQQIKQLETQLKELELALEELELLDEDTKvykligdvlvkqDKEEVKEQLEERKETLEKEIKTLEKQ 81
|
90
....*....|
gi 1465187875 845 AEIKDTTLEE 854
Cdd:pfam01920 82 LEKLEKELEE 91
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
769-887 |
2.44e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 42.74 E-value: 2.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 769 QKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKE-------NKRL 841
Cdd:pfam05911 680 TEENKRLKEEFEQLKSEKENLEVELASCTENLESTKS---QLQESEQLIAELRSELASLKESNSLAETQlkcmaesYEDL 756
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1465187875 842 RQQAEIKDTTLEENNVKIGNLEKEnktLSKEIGIYKESCVRLKELE 887
Cdd:pfam05911 757 ETRLTELEAELNELRQKFEALEVE---LEEEKNCHEELEAKCLELQ 799
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
619-938 |
2.60e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.97 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 619 HYKEKGERAEELENELhhLEKENELLQKKITNLKITCEKIEALEQENseLERENRKLKKTLDSFKNLTFQLESLekensq 698
Cdd:PLN02939 64 KLQSNTDENGQLENTS--LRTVMELPQKSTSSDDDHNRASMQRDEAI--AAIDNEQQTNSKDGEQLSDFQLEDL------ 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 699 ldeenLELRRNVES--LKCASMKMAQLQLENKELeSEKEQLKKGLELLKASFKKT-ERLEVSYQGlDIENQRLQKTLENS 775
Cdd:PLN02939 134 -----VGMIQNAEKniLLLNQARLQALEDLEKIL-TEKEALQGKINILEMRLSETdARIKLAAQE-KIHVEILEEQLEKL 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 776 NKKIQQ-----------LESELQDLEMEN-------QTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE-------KD 830
Cdd:PLN02939 207 RNELLIrgateglcvhsLSKELDVLKEENmllkddiQFLKAELIEVAETEERVFKLEKERSLLDASLRELEskfivaqED 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 831 KKQL---------EK-EN-----KRLRQQAEIKDTTLEENNVKIGNLEKENKTLsKEIGIYKESCVRLKELEKENK---E 892
Cdd:PLN02939 287 VSKLsplqydcwwEKvENlqdllDRATNQVEKAALVLDQNQDLRDKVDKLEASL-KEANVSKFSSYKVELLQQKLKlleE 365
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 1465187875 893 LVKRATIDIKTLVTLREDLVSEklktqqMNNDLEKLTHELEKIGLN 938
Cdd:PLN02939 366 RLQASDHEIHSYIQLYQESIKE------FQDTLSKLKEESKKRSLE 405
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
305-512 |
2.77e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 2.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 305 ARMYRDELDALREKAVR--VDKLESEVSRYKERLHDIEfykARVEELKEDNQVLL--ETKTMLEDQLEGTRARsdkLHEL 380
Cdd:COG3206 158 AEAYLEQNLELRREEARkaLEFLEEQLPELRKELEEAE---AALEEFRQKNGLVDlsEEAKLLLQQLSELESQ---LAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 381 EKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQISRTSeLSEAPQ--------KSLGH 452
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEA-----ELAELSARY-TPNHPDvialraqiAALRA 305
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 453 EVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILEN 512
Cdd:COG3206 306 QLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
495-605 |
2.80e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 2.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ-----ENEHLNQTVSS 569
Cdd:PRK12704 83 ELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisgltAEEAKEILLEK 162
|
90 100 110
....*....|....*....|....*....|....*.
gi 1465187875 570 LRQRSQISAEARVKDIEKEnkilhesIKETSSKLSK 605
Cdd:PRK12704 163 VEEEARHEAAVLIKEIEEE-------AKEEADKKAK 191
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
566-742 |
3.16e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.39 E-value: 3.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 566 TVSSLRQRSQISAEARvkdiekenKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERA--EELENELHHLEKENEL 643
Cdd:PRK12705 21 LVVLLKKRQRLAKEAE--------RILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRerEELQREEERLVQKEEQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 644 LQKKitnlkitCEKIEALEQEnseLERENRKLKKtldsfknltfQLESLEKENSQLDEENLElrrnVESLKCASMKMAQL 723
Cdd:PRK12705 93 LDAR-------AEKLDNLENQ---LEEREKALSA----------RELELEELEKQLDNELYR----VAGLTPEQARKLLL 148
|
170
....*....|....*....
gi 1465187875 724 QLENKELESEKEQLKKGLE 742
Cdd:PRK12705 149 KLLDAELEEEKAQRVKKIE 167
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
257-605 |
3.36e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 42.53 E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 257 KAKIRRLRQELEEKTEQLLDCKQE--------LEQMeieLKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLEse 328
Cdd:PLN03229 428 KTPVRELEGEVEKLKEQILKAKESsskpselaLNEM---IEKLKKEIDLEYTEAVIAMGLQERLENLREEFSKANSQD-- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 329 vsrykERLHDIefYKARVEELKEDNQVLLETKTmledQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDrKKIEEL 408
Cdd:PLN03229 503 -----QLMHPV--LMEKIEKLKDEFNKRLSRAP----NYLSLKYKLDMLNEFSRAKALSEKKSKAEKLKAEIN-KKFKEV 570
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 409 MEENmtlEMAQKqsmdeslhlgweLEQISRTSELSEApqkSLGHEVNELTSSRLLKLEMENQ-SLTKTVEELRTTVDSVE 487
Cdd:PLN03229 571 MDRP---EIKEK------------MEALKAEVASSGA---SSGDELDDDLKEKVEKMKKEIElELAGVLKSMGLEVIGVT 632
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 488 GNAsKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQEnehLNQTV 567
Cdd:PLN03229 633 KKN-KDTAEQTPPPNLQEKIESLNEEINKKIERVIRSSDLKSKIELLKLEVAKASKTPDVTEKEKIEALEQQ---IKQKI 708
|
330 340 350
....*....|....*....|....*....|....*...
gi 1465187875 568 SSLRQRSQIsaEARVKDIEKENKILHESIKETSSKLSK 605
Cdd:PLN03229 709 AEALNSSEL--KEKFEELEAELAAARETAAESNGSLKN 744
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
578-702 |
3.39e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 42.38 E-value: 3.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 578 AEARVKdIEKENKIlhESIKETSSKLSKIEFEKRQIKKELEHYKEkgERAEELENELHHLEKENELLQKKITNLKITCEK 657
Cdd:COG0542 398 AAARVR-MEIDSKP--EELDELERRLEQLEIEKEALKKEQDEASF--ERLAELRDELAELEEELEALKARWEAEKELIEE 472
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 1465187875 658 IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKEnsQLDEE 702
Cdd:COG0542 473 IQELKEELEQRYGKIPELEKELAELEEELAELAPLLRE--EVTEE 515
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
262-854 |
3.45e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 42.43 E-value: 3.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELdALREKAVRvdkleSEVSRYKERLHDIEF 341
Cdd:pfam07111 56 EGSQALSQQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDAL-AVAEKAGQ-----AEAEGLRAALAGAEM 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 342 YKARVEELKEdnQVLLETKTMLEDQLEG-TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK 420
Cdd:pfam07111 130 VRKNLEEGSQ--RELEEIQRLHQEQLSSlTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLS 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 421 QSMDE---SLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSrLLKLEMENQSLTKTVEELRTTVDSVegnaSKILKME 497
Cdd:pfam07111 208 KTQEEleaQVTLVESLRKYVGEQVPPEVHSQTWELERQELLDT-MQHLQEDRADLQATVELLQVRVQSL----THMLALQ 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 498 KEnqRLSKKVEILEneiVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS 577
Cdd:pfam07111 283 EE--ELTRKIQPSD---SLEPEFPKKCRSLLNRWREKVFALMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAIL 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 578 AEArVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEkgeraeELENELHHLEKENELLQKKITNLKITCEK 657
Cdd:pfam07111 358 QRA-LQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEE------QLKFVVNAMSSTQIWLETTMTRVEQAVAR 430
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 658 IEALeqeNSELERENRKLKkTLDSFKNLTFQLESLEKENSQLDEENLELRRNVeslkcaSMKMAQLQLENKELESEKEql 737
Cdd:pfam07111 431 IPSL---SNRLSYAVRKVH-TIKGLMARKVALAQLRQESCPPPPPAPPVDADL------SLELEQLREERNRLDAELQ-- 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 738 kkglelLKASFKKTERLEVSYQGlDIENQRLqktlensNKKIQQLESELQDLEmenQTLQKNLEELKISSKRLEQLEKEN 817
Cdd:pfam07111 499 ------LSAHLIQQEVGRAREQG-EAERQQL-------SEVAQQLEQELQRAQ---ESLASVGQQLEVARQGQQESTEEA 561
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 1465187875 818 KSLEQETSQLEKDKKQLEKEN-----KRLRQQAEIKDTTLEE 854
Cdd:pfam07111 562 ASLRQELTQQQEIYGQALQEKvaeveTRLREQLSDTKRRLNE 603
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
535-846 |
3.46e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.64 E-value: 3.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 535 KAQLEKTIETLRENSERQIKiLEQENEHLNQTVSSLrqrsqiSAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK 614
Cdd:PRK04863 792 RAEREELAERYATLSFDVQK-LQRLHQAFSRFIGSH------LAVAFEADPEAELRQLNRRRVELERALADHESQEQQQR 864
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 615 KELEHYKEK-------------------GERAEELENELHHLEKEN----------ELLQKKITNLKITCEKIEALEQEN 665
Cdd:PRK04863 865 SQLEQAKEGlsalnrllprlnlladetlADRVEEIREQLDEAEEAKrfvqqhgnalAQLEPIVSVLQSDPEQFEQLKQDY 944
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQ-LDEENLELrrnVESLKcasmkmAQLqlenKELESEKEQLKKGLELL 744
Cdd:PRK04863 945 QQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAeMLAKNSDL---NEKLR------QRL----EQAEQERTRAREQLRQA 1011
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 745 KASFkkTERLEVsYQGLDIENQRLQKTLensnkkiQQLESELQDL------EMENQ------TLQKNLEElkiSSKRLEQ 812
Cdd:PRK04863 1012 QAQL--AQYNQV-LASLKSSYDAKRQML-------QELKQELQDLgvpadsGAEERararrdELHARLSA---NRSRRNQ 1078
|
330 340 350
....*....|....*....|....*....|....
gi 1465187875 813 LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:PRK04863 1079 LEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVV 1112
|
|
| TOPEUc |
smart00435 |
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ... |
770-855 |
3.66e-03 |
|
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras
Pssm-ID: 214661 [Multi-domain] Cd Length: 391 Bit Score: 41.95 E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 770 KTLENSNKKIQQLESELQDLEMENQTLQKNL---EELKISSKRL-EQLEKENKSLEQETSQLEKDKKQLEKENKRLrQQA 845
Cdd:smart00435 277 KSMEKLQEKIKALKYQLKRLKKMILLFEMISdlkRKLKSKFERDnEKLDAEVKEKKKEKKKEEKKKKQIERLEERI-EKL 355
|
90
....*....|
gi 1465187875 846 EIKDTTLEEN 855
Cdd:smart00435 356 EVQATDKEEN 365
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
652-1028 |
3.98e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 42.15 E-value: 3.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 652 KITCEKIEALEQENSELERENRKLKKTLdsfknltfqlesLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKElE 731
Cdd:PLN03229 418 KVNMKKREAVKTPVRELEGEVEKLKEQI------------LKAKESSSKPSELALNEMIEKLK------KEIDLEYTE-A 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 732 SEKEQLKKGLELLKASFKKTerlevsyqglDIENQRLQKTLENSNKKIQQlESELQDLEMENQT-LQKNLEELKISSKRL 810
Cdd:PLN03229 479 VIAMGLQERLENLREEFSKA----------NSQDQLMHPVLMEKIEKLKD-EFNKRLSRAPNYLsLKYKLDMLNEFSRAK 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeIKDTTLEENNVKIGNLEKEnktlskeigiYKESCVRLK-ELEKE 889
Cdd:PLN03229 548 ALSEKKSKAEKLKAEINKKFKEVMDRPEIKEKMEA-LKAEVASSGASSGDELDDD----------LKEKVEKMKkEIELE 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 890 NKELVKRATIDIkTLVTLREDLVSEKLKTQQMNNDLEKLThelEKIGLNKERLLhdeQSTD-DSRYKLLESKLESTLKKS 968
Cdd:PLN03229 617 LAGVLKSMGLEV-IGVTKKNKDTAEQTPPPNLQEKIESLN---EEINKKIERVI---RSSDlKSKIELLKLEVAKASKTP 689
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1465187875 969 LEIKEEKIAALEarleestnynQQLRQELKTVkKNYEALKQRQDE-ERMVQSSPPISGEDN 1028
Cdd:PLN03229 690 DVTEKEKIEALE----------QQIKQKIAEA-LNSSELKEKFEElEAELAAARETAAESN 739
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
183-345 |
4.22e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 4.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 183 QEDIEPLLKNMALHLKRLIDERDEHSETIIEL--SEERDGLHFLPHASSSAQSPCGSPGMKR-TESRQHLSVELADAKAK 259
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQKEELAELLRALyrLGRQPPLALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRADLAE 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 260 IRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARM-YRDELDALREKAVR----VDKLESEVSRYKE 334
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAeLAAELAELQQEAEElealIARLEAEAAAAAE 241
|
170
....*....|.
gi 1465187875 335 RLHDIEFYKAR 345
Cdd:COG4942 242 RTPAAGFAALK 252
|
|
| PTZ00341 |
PTZ00341 |
Ring-infected erythrocyte surface antigen; Provisional |
375-1040 |
4.51e-03 |
|
Ring-infected erythrocyte surface antigen; Provisional
Pssm-ID: 173534 [Multi-domain] Cd Length: 1136 Bit Score: 42.08 E-value: 4.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 375 DKLHELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHE 453
Cdd:PTZ00341 414 DLLFDLEKQKyMDMLDGSEDESVEDNEEEHSGDANEEELSVDEHVEEHNADDSGEQQSDDESGEHQSVNEIVEEQSVNEH 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 454 VNELTSSRLLKLEMENQSLTKTV----EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQ---SLQNCQN 526
Cdd:PTZ00341 494 VEEPTVADIVEQETVDEHVEEPAvdenEEQQTADEHVEEPTIAEEHVEEEISTAEEHIEEPASDVQQDSEaapTIEIPDT 573
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 527 LSKDLMKEKAQLEktietLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV-KDIEKE---NKILHESIKETS-- 600
Cdd:PTZ00341 574 LFYDILGVGVNAD-----MKEISERYFKLAENYYPPKRSGNEGFHKFKKINEAYQIlGDIDKKkmyNKFGYDGIKGVNfi 648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 601 --------SKLSKIEF--EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKiTNLKITCEKIEALEQENSELER 670
Cdd:PTZ00341 649 hpsifyllASLEKFADftGSPQIVTLLKFFFEKKLSMNDLDNKSEHLLKFMEQYQKE-REAHISENLINILQPCIAGDRK 727
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 671 ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVeslKCASMKMAQLQLENKE-LESEKEQLkkgLELLKASFK 749
Cdd:PTZ00341 728 WDVPIIDKIEELKGSPFDIAIIDSIGWIFKHVAKSHLKKP---KKAAKKLEQRSKANKEeLANENNKL---MNILKEYFG 801
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 750 KTERLE-----VSYQGLDIENQRLQKTLENSNKKIQQ----------LESELQDLE-----MENQTLQKNLEELKISSKR 809
Cdd:PTZ00341 802 NNEQINsitynFENINLNEDNENGSKKILDLNHKDQKeifeeiisyiVDISLSDIEntaknAAEQILSDEGLDEKKLKKR 881
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 810 LEQLEKENKSLEQETSQLEKDKKQLEKE---------------NKRLRQQAEIKDTTLEEN-NVKIGNLEKENKTLSKEI 873
Cdd:PTZ00341 882 AESLKKLANAIEKYAGGGKKDKKAKKKDakdlsgniaheinliNKELKNQNENVPEHLKEHaEANIEEDAEENVEEDAEE 961
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDlVSEKLKTQQMNNDLEKLTHELEKIG-LNKERLLHDEQSTDDS 952
Cdd:PTZ00341 962 NVEENVEENVEENVEENVEENVEENVEENVEENVEEN-VEENIEENVEENVEENIEENVEEYDeENVEEVEENVEEYDEE 1040
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 953 RYKLLESKLESTLKKSLE-----IKEEKIAALEARLEESTNYNQQlrqelKTVKKNYEALKQRQDE--ERMVQSSPPISG 1025
Cdd:PTZ00341 1041 NVEEIEENAEENVEENIEenieeYDEENVEEIEENIEENIEENVE-----ENVEENVEEIEENVEEnvEENAEENAEENA 1115
|
730
....*....|....*
gi 1465187875 1026 EDNKwERESQETTRE 1040
Cdd:PTZ00341 1116 EENA-EEYDDENPEE 1129
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1208-1376 |
4.76e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 4.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1208 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEA 1287
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1288 EFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELR 1367
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
|
....*....
gi 1465187875 1368 RQKEKLEEK 1376
Cdd:COG4942 178 ALLAELEEE 186
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1148-1377 |
4.77e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 4.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1148 DLKSLyDSLIKDHekleLLHERQASE-YESLISKHGTLKSAHKNLE-----VEH----RDLEDRYNQLLKQKGQLEDLEK 1217
Cdd:COG4913 205 PIGDL-DDFVREY----MLEEPDTFEaADALVEHFDDLERAHEALEdareqIELlepiRELAERYAAARERLAELEYLRA 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1218 MLKVEQEKMLLENKNHETVAAEykklcGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQ-TRLEAEFSKLKEQY 1296
Cdd:COG4913 280 ALRLWFAQRRLELLEAELEELR-----AELARLEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLEREL 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1297 QQLditSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmlqnRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEK 1376
Cdd:COG4913 355 EER---ERRRARLEALLAALGLPLPASAEEFAALRAEA----AALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
|
.
gi 1465187875 1377 I 1377
Cdd:COG4913 428 I 428
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
485-840 |
5.48e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 41.55 E-value: 5.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 485 SVEGNASKILKMEKENQRLSKKVEILENEIVQE-KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQikileqenehl 563
Cdd:pfam05667 223 EEEWNSQGLASRLTPEEYRKRKRTKLLKRIAEQlRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTD----------- 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 564 nqtvsslRQRSQISAEARVKDIEKENkilhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENEL 643
Cdd:pfam05667 292 -------TGLTKGSRFTHTEKLQFTN----EAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKK 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 644 LQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNltfqleslekensqlDEENLElrrnveslkcasmkmaql 723
Cdd:pfam05667 361 LESSIKQVE---EELEELKEQNEELEKQYKVKKKTLDLLPD---------------AEENIA------------------ 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 724 qlenkELESEKEQLKKGLELLKASFKKterlevsYQGLDIEnqrlqktlensnkKIQQLESELQDLEMENqtlQKNLEEL 803
Cdd:pfam05667 405 -----KLQALVDASAQRLVELAGQWEK-------HRVPLIE-------------EYRALKEAKSNKEDES---QRKLEEI 456
|
330 340 350
....*....|....*....|....*....|....*..
gi 1465187875 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Cdd:pfam05667 457 KELREKIKEVAEEAKQKEELYKQLVAEYERLPKDVSR 493
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
625-683 |
5.75e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 41.36 E-value: 5.75e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1465187875 625 ERAEELENELHHLEKENELLQkkitnlkitcEKIEALEQENSELERENRKLKKTLDSFK 683
Cdd:PRK03992 1 ERLEALEERNSELEEQIRQLE----------LKLRDLEAENEKLERELERLKSELEKLK 49
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
675-894 |
6.56e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.44 E-value: 6.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 675 LKKTLDSFKNLTFQ---LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELesekEQLKKGLELLKASFKKT 751
Cdd:PRK11281 65 LEQTLALLDKIDRQkeeTEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSL----RQLESRLAQTLDQLQNA 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 752 ERLEVSYQGLDIENQ----RLQKTLENSNKKIQQLESELQDLEMENQTLqknleelkiSSKRLEQLEKENKSLEQETSQl 827
Cdd:PRK11281 141 QNDLAEYNSQLVSLQtqpeRAQAALYANSQRLQQIRNLLKGGKVGGKAL---------RPSQRVLLQAEQALLNAQNDL- 210
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1465187875 828 ekdKKQLEKENKRLRQQAEIKdttLEENNVKIGNLEKENKTLSKEIgiykeSCVRLKELEKENKELV 894
Cdd:PRK11281 211 ---QRKSLEGNTQLQDLLQKQ---RDYLTARIQRLEHQLQLLQEAI-----NSKRLTLSEKTVQEAQ 266
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1135-1357 |
7.11e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.03 E-value: 7.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1135 LENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGqlED 1214
Cdd:pfam07888 50 QEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRA--AH 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1215 LEKMLKVEQEKMLLENKNHETVAaeykklcgENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKE 1294
Cdd:pfam07888 128 EARIRELEEDIKTLTQRVLERET--------ELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRN 199
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1465187875 1295 QYQQLDITSTKLNNQCELLSQlkgnleeenrhLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR 1357
Cdd:pfam07888 200 SLAQRDTQVLQLQDTITTLTQ-----------KLTTAHRKEAENEALLEELRSLQERLNASER 251
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
1056-1137 |
7.11e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 40.99 E-value: 7.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1056 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKL--QVENSTLNSQST-----SLMNQNAQL 1128
Cdd:COG3524 224 ATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALEKQ---IAAERARLtgASGGDSLASLLAeyerlELEREFAEK 300
|
90
....*....|.
gi 1465187875 1129 LIQQS--SLEN 1137
Cdd:COG3524 301 AYTSAlaALEQ 311
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
784-820 |
7.14e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 7.14e-03
10 20 30
....*....|....*....|....*....|....*..
gi 1465187875 784 SELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820
Cdd:PRK13922 69 ASLFDLREENEELKKELLELESRLQELEQLEAENARL 105
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
736-844 |
7.17e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 39.89 E-value: 7.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 736 QLKKGLELLKASFKKTERLevsYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKnleelkiSSKRLEQLEK 815
Cdd:pfam13851 30 SLKEEIAELKKKEERNEKL---MSEIQQENKRLTEPLQKAQEEVEELRKQLENYEKDKQSLKN-------LKARLKVLEK 99
|
90 100
....*....|....*....|....*....
gi 1465187875 816 ENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam13851 100 ELKDLKWEHEVLEQRFEKVERERDELYDK 128
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
608-732 |
7.55e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.92 E-value: 7.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 608 FEKRQIKKELEHYKEKGER-AEELENELHHLEKENEL-LQKKITNLKITCEKieALEQENSELERENRKLKKTLDSFKNl 685
Cdd:PRK12704 24 VRKKIAEAKIKEAEEEAKRiLEEAKKEAEAIKKEALLeAKEEIHKLRNEFEK--ELRERRNELQKLEKRLLQKEENLDR- 100
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1465187875 686 tfQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE-NKELES 732
Cdd:PRK12704 101 --KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEqLQELER 146
|
|
| Prominin |
pfam05478 |
Prominin; The prominins are an emerging family of proteins that among the multispan membrane ... |
635-873 |
7.78e-03 |
|
Prominin; The prominins are an emerging family of proteins that among the multispan membrane proteins display a novel topology. Mouse prominin and human prominin (mouse)-like 1 (PROML1) are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. The exact function of prominin is unknown although in humans defects in PROM1, the gene coding for prominin, cause retinal degeneration.
Pssm-ID: 461660 [Multi-domain] Cd Length: 799 Bit Score: 41.07 E-value: 7.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 635 HHLEKENELLQKKI----TNLKITCEKIEALEQEN-SELERenrKLKKTLDSFKNLTF-----QLESleKENSQLDEenl 704
Cdd:pfam05478 169 RGIGESTETMRRGLrdlrTFLSDVPQHIDHVLVQNySELQD---HVSDDLDDAGKHIGldihdTLES--NVYPALAE--- 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 705 eLRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKasfkktERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Cdd:pfam05478 241 -LERILQNMPEAKDLLEQVNALLKDLRFYGTQLRDGLRGVK------RDLNYALSNPLCTTQECDKFLSSLSIEFLDTSA 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 785 EL-----QDLEMEN--QTLQKNLEelKISSKRLEQLEKENKSLEQETSQLEKD-KKQLEKENKRLRQQAE-IKDTTLEEN 855
Cdd:pfam05478 314 CLdqlpnVDEFLENvkGVIETNLS--SIVQEGLDRFNNIPEKVKNQTAGVVPPlKRALAQIREQIRTLATdIPRDALSAV 391
|
250
....*....|....*...
gi 1465187875 856 NVKIGNLEKENKTLSKEI 873
Cdd:pfam05478 392 SSDIHNTERSSRTFLDVV 409
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
531-675 |
7.86e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 39.14 E-value: 7.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 531 LMKEKAQLEKTIETLRENSERQIKILEQENEH----LNQTVSSLR------QRSQISAEARVKDIEKENKILHESIKETS 600
Cdd:pfam08614 19 LEAENAKLQSEPESVLPSTSSSKLSKASPQSAsiqsLEQLLAQLReelaelYRSRGELAQRLVDLNEELQELEKKLREDE 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1465187875 601 SKLSKIEFEKRQIKKELEhykekgeraeELENELHHLEKENELLQKKITNLKITcekIEALEQENSELERENRKL 675
Cdd:pfam08614 99 RRLAALEAERAQLEEKLK----------DREEELREKRKLNQDLQDELVALQLQ---LNMAEEKLRKLEKENREL 160
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
810-851 |
8.59e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 8.59e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 1465187875 810 LEQLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQAEIKDTT 851
Cdd:PRK13922 71 LFDLREENEELKKELLELESRLqelEQLEAENARLRELLNLKESL 115
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
768-854 |
8.77e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 40.10 E-value: 8.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 768 LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:COG4026 133 LREELLELKEKIDEIAKEKEKLTKENEELESELEELR---EEYKKLREENSILEEEFDNIKSEYSDLKSRFEELLKKRLL 209
|
....*..
gi 1465187875 848 KDTTLEE 854
Cdd:COG4026 210 EVFSLEE 216
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
776-1242 |
8.78e-03 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 40.83 E-value: 8.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 776 NKKIQQLESELQDLEMENQTLQKNLEELK-------ISSKRLEQLEKENKSLEQETSQLEKDKKQLekenkrlRQQAEIK 848
Cdd:pfam05622 20 DQQVSLLQEEKNSLQQENKKLQERLDQLEsgddsgtPGGKKYLLLQKQLEQLQEENFRLETARDDY-------RIKCEEL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 849 DTTLEENNVKIGNLEK---ENKTLSKEIGIYKESCVRLKELEkenkelvkrATIDiktlvtlredlvSEKLKTQQMNnDL 925
Cdd:pfam05622 93 EKEVLELQHRNEELTSlaeEAQALKDEMDILRESSDKVKKLE---------ATVE------------TYKKKLEDLG-DL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 926 EKLTHELEkiglnkERLLHDEQSTDDSRYkllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYE 1005
Cdd:pfam05622 151 RRQVKLLE------ERNAEYMQRTLQLEE---ELKKANALRGQLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1006 AL---KQRQDEERMVQSsppisgEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQ--ALKTQLKQLETQNNNLQ 1080
Cdd:pfam05622 222 ALqkeKERLIIERDTLR------ETNEELRCAQLQQAELSQADALLSPSSDPGDNLAAEIMpaEIREKLIRLQHENKMLR 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1081 -AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKslydslikd 1159
Cdd:pfam05622 296 lGQEGSYRERLTELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLE--------- 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1160 hEKLELLHERQAseyesliskhgtlksahknlevehrdledrynQLLKQKGQLEDLE------KMLKVEQEKMLLENKNH 1233
Cdd:pfam05622 367 -EHLEKLHEAQS--------------------------------ELQKKKEQIEELEpkqdsnLAQKIDELQEALRKKDE 413
|
490
....*....|.
gi 1465187875 1234 ETVAAE--YKK 1242
Cdd:pfam05622 414 DMKAMEerYKK 424
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
184-340 |
9.14e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.20 E-value: 9.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 184 EDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQspcgspgMKRTESRQHLSVELADAKAKIRRL 263
Cdd:TIGR02168 841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL-------ALLRSELEELSEELRELESKRSEL 913
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1465187875 264 RQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLlsdarsarmYRDELDALREKavrVDKLESEVSRYKERLHDIE 340
Cdd:TIGR02168 914 RRELEELREKLAQLELRLEGLEVRIDNLQERLSEE---------YSLTLEEAEAL---ENKIEDDEEEARRRLKRLE 978
|
|
| Atg16_CCD |
cd22887 |
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
1045-1114 |
9.34e-03 |
|
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins.
Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 37.16 E-value: 9.34e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 1045 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Cdd:cd22887 3 ESELQELEKRLAELEAELASLEEEIKDLEEELKEKNKANEILNDELIALQIENNLLEEKLRKLQEENDEL 72
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
814-1036 |
9.35e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.58 E-value: 9.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEscvRLKELEKENKEL 893
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEA---EIEERREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1465187875 894 VKRATIDIKTLVTLREDLVSEKLktQQMNNDLEKLTheleKIGLNKERLLhDEQSTDDSRYKLLESKLE---STLKKSLE 970
Cdd:COG3883 92 ARALYRSGGSVSYLDVLLGSESF--SDFLDRLSALS----KIADADADLL-EELKADKAELEAKKAELEaklAELEALKA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1465187875 971 IKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQE 1036
Cdd:COG3883 165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAA 230
|
|
| |
