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Conserved domains on  [gi|1424027871|ref|NP_001351796|]
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gamma-interferon-inducible protein 16 isoform 3 [Homo sapiens]

Protein Classification

Pyrin and HIN domain-containing protein( domain architecture ID 10169747)

protein containing domains Pyrin, DUF5585, and HIN

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HIN pfam02760
HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per ...
 201-369 2.74e-89

HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per protein, and is found associated with the PAAD/DAPIN domain pfam02758.


:

Pssm-ID: 460680  Cd Length: 168  Bit Score: 278.33  E-value: 2.74e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 201 QKRPVIVKVLSTTKPFEYETPEmEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVS 280
Cdd:pfam02760   1 QKGPKEVMVLKATEPFEYESQE-GKKKMFHATVATESEFFRVKVFNINLKEKFIPKKVIAISDYFGRNGFLEVNEASSVS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 281 EAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEGD 360
Cdd:pfam02760  80 EAGPDQKMEVPKSIIRKANETPKINKLKKQPSGTIVNGLFTVHKKTVNKKNTIYEIQDNTGKMEVVVYGKLTNIKCEEGD 159


                  ....*....
gi 1424027871 361 KLQLFCFRL 369
Cdd:pfam02760 160 KLRLFCFEL 168
HIN pfam02760
HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per ...
 574-740 3.39e-89

HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per protein, and is found associated with the PAAD/DAPIN domain pfam02758.


:

Pssm-ID: 460680  Cd Length: 168  Bit Score: 277.94  E-value: 3.39e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 574 QSDLKEVMVLNATESFVYE-PKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVAD 652
Cdd:pfam02760   1 QKGPKEVMVLKATEPFEYEsQEGKKKMFHATVATESEFFRVKVFNINLKEKFIPKKVIAISDYFGRNGFLEVNEASSVSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 653 VNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDK 732
Cdd:pfam02760  81 AGPDQKMEVPKSIIRKANETPKINKLKKQPSGTIVNGLFTVHKKTVNKKNTIYEIQDNTGKMEVVVYGKLTNIKCEEGDK 160


                  ....*...
gi 1424027871 733 LKLTCFEL 740
Cdd:pfam02760 161 LRLFCFEL 168
Pyrin cd08305
Pyrin: a protein-protein interaction domain; The Pyrin domain (or PYD), also called DAPIN or ...
 10-83 2.38e-32

Pyrin: a protein-protein interaction domain; The Pyrin domain (or PYD), also called DAPIN or PAAD, is a subfamily of the Death Domain (DD) superfamily and it functions in several signaling pathways. The Pyrin domain is found at the N-terminus of a variety of proteins and serves as a linker that recruits other domains into signaling complexes. Pyrin-containing proteins include NALPs, ASC (Apoptosis-associated speck-like protein containing a CARD), and the interferon-inducible p200 (IFI-200) family of proteins which includes the human IFI-16, myeloid cell nuclear differentiation antigen (MNDA) and absent in melanoma (AIM) 2. NALPs are members of the NBS-LRR family of proteins possessing a tripartite domain structure including a C-terminal LRR (leucine-rich repeats), a central nucleotide-binding site (NBS) domain or NACHT (for neuronal apoptosis inhibitor protein, CIITA, HET-E and TP1), and an N-terminal protein-protein interaction domain, which is a Pyrin domain in the case of NALPs. ASC and NALPs are involved in the regulation of inflammation. ASC, NALP1 and NALP3 are involved in the assembly of the 'inflammasome', a multiprotein platform which is formed in response to infection or injury and is responsible for caspase-1 activation and regulation of IL-1beta maturation. NALP12 functions as a negative regulator of inflammation. The p200 proteins are involved in the regulation of cell cycle and differentiation. In general, DDs are protein-protein interaction domains found in a variety of domain architectures. Their common feature is that they form homodimers by self-association or heterodimers by associating with other members of the DD superfamily including Caspase activation and recruitment domain (CARD) and Death Effector Domain (DED). They serve as adaptors in signaling pathways and can recruit other proteins into signaling complexes.


:

Pssm-ID: 260019  Cd Length: 73  Bit Score: 119.72  E-value: 2.38e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424027871  10 LLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPtLEDLAETLK 83
Cdd:cd08305     1 LLTGLENITDEEFKMFKSLLASELKLTRKMQEEYDRIEIADLMEEKFGEDAGLDKLIEVFEDMP-LRSLANQLQ 73
PTZ00449 super family cl33186
104 kDa microneme/rhoptry antigen; Provisional
 100-215 2.20e-04

104 kDa microneme/rhoptry antigen; Provisional


The actual alignment was detected with superfamily member PTZ00449:

Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 45.07  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 100 KEVDATSPAPSTSSTVKTEGAEATPGAQKRKKS-----TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPK-TSL 173
Cdd:PTZ00449  538 KESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKlPEL 617

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1424027871 174 SAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKP 215
Cdd:PTZ00449  618 LDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKP 659
 
Name Accession Description Interval E-value
HIN pfam02760
HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per ...
 201-369 2.74e-89

HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per protein, and is found associated with the PAAD/DAPIN domain pfam02758.


Pssm-ID: 460680  Cd Length: 168  Bit Score: 278.33  E-value: 2.74e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 201 QKRPVIVKVLSTTKPFEYETPEmEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVS 280
Cdd:pfam02760   1 QKGPKEVMVLKATEPFEYESQE-GKKKMFHATVATESEFFRVKVFNINLKEKFIPKKVIAISDYFGRNGFLEVNEASSVS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 281 EAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEGD 360
Cdd:pfam02760  80 EAGPDQKMEVPKSIIRKANETPKINKLKKQPSGTIVNGLFTVHKKTVNKKNTIYEIQDNTGKMEVVVYGKLTNIKCEEGD 159


                  ....*....
gi 1424027871 361 KLQLFCFRL 369
Cdd:pfam02760 160 KLRLFCFEL 168
HIN pfam02760
HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per ...
 574-740 3.39e-89

HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per protein, and is found associated with the PAAD/DAPIN domain pfam02758.


Pssm-ID: 460680  Cd Length: 168  Bit Score: 277.94  E-value: 3.39e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 574 QSDLKEVMVLNATESFVYE-PKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVAD 652
Cdd:pfam02760   1 QKGPKEVMVLKATEPFEYEsQEGKKKMFHATVATESEFFRVKVFNINLKEKFIPKKVIAISDYFGRNGFLEVNEASSVSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 653 VNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDK 732
Cdd:pfam02760  81 AGPDQKMEVPKSIIRKANETPKINKLKKQPSGTIVNGLFTVHKKTVNKKNTIYEIQDNTGKMEVVVYGKLTNIKCEEGDK 160


                  ....*...
gi 1424027871 733 LKLTCFEL 740
Cdd:pfam02760 161 LRLFCFEL 168
Pyrin cd08305
Pyrin: a protein-protein interaction domain; The Pyrin domain (or PYD), also called DAPIN or ...
 10-83 2.38e-32

Pyrin: a protein-protein interaction domain; The Pyrin domain (or PYD), also called DAPIN or PAAD, is a subfamily of the Death Domain (DD) superfamily and it functions in several signaling pathways. The Pyrin domain is found at the N-terminus of a variety of proteins and serves as a linker that recruits other domains into signaling complexes. Pyrin-containing proteins include NALPs, ASC (Apoptosis-associated speck-like protein containing a CARD), and the interferon-inducible p200 (IFI-200) family of proteins which includes the human IFI-16, myeloid cell nuclear differentiation antigen (MNDA) and absent in melanoma (AIM) 2. NALPs are members of the NBS-LRR family of proteins possessing a tripartite domain structure including a C-terminal LRR (leucine-rich repeats), a central nucleotide-binding site (NBS) domain or NACHT (for neuronal apoptosis inhibitor protein, CIITA, HET-E and TP1), and an N-terminal protein-protein interaction domain, which is a Pyrin domain in the case of NALPs. ASC and NALPs are involved in the regulation of inflammation. ASC, NALP1 and NALP3 are involved in the assembly of the 'inflammasome', a multiprotein platform which is formed in response to infection or injury and is responsible for caspase-1 activation and regulation of IL-1beta maturation. NALP12 functions as a negative regulator of inflammation. The p200 proteins are involved in the regulation of cell cycle and differentiation. In general, DDs are protein-protein interaction domains found in a variety of domain architectures. Their common feature is that they form homodimers by self-association or heterodimers by associating with other members of the DD superfamily including Caspase activation and recruitment domain (CARD) and Death Effector Domain (DED). They serve as adaptors in signaling pathways and can recruit other proteins into signaling complexes.


Pssm-ID: 260019  Cd Length: 73  Bit Score: 119.72  E-value: 2.38e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424027871  10 LLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPtLEDLAETLK 83
Cdd:cd08305     1 LLTGLENITDEEFKMFKSLLASELKLTRKMQEEYDRIEIADLMEEKFGEDAGLDKLIEVFEDMP-LRSLANQLQ 73
PYRIN pfam02758
PAAD/DAPIN/Pyrin domain; This domain is predicted to contain 6 alpha helices and to have the ...
 10-80 1.94e-15

PAAD/DAPIN/Pyrin domain; This domain is predicted to contain 6 alpha helices and to have the same fold as the pfam00531 domain. This similarity may mean that this is a protein-protein interaction domain.


Pssm-ID: 460678  Cd Length: 76  Bit Score: 71.47  E-value: 1.94e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424027871  10 LLKGLEVINDYHFRMVKSLLSNDLKLNL------KMrEEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPtLEDLAE 80
Cdd:pfam02758   2 LLWYLEELSEEEFKKFKSLLEDEPEEGLrsiprgKL-EKADRLDLADLLVEHYGEDAAVDVTIEILKKIN-LKDLAE 76
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 100-215 2.20e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 45.07  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 100 KEVDATSPAPSTSSTVKTEGAEATPGAQKRKKS-----TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPK-TSL 173
Cdd:PTZ00449  538 KESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKlPEL 617

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1424027871 174 SAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKP 215
Cdd:PTZ00449  618 LDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKP 659
PHA03058 PHA03058
Hypothetical protein; Provisional
 14-84 8.60e-03

Hypothetical protein; Provisional


Pssm-ID: 222966  Cd Length: 124  Bit Score: 37.08  E-value: 8.60e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424027871  14 LEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPTLEDLAETLKK 84
Cdd:PHA03058   11 LENLTDYQFKMLIFLTQDDLNIEEEEKEKLDRIDLAEKISEKYPGIRSIYFLKKVISEIPNTEYVDSLLSR 81
 
Name Accession Description Interval E-value
HIN pfam02760
HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per ...
 201-369 2.74e-89

HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per protein, and is found associated with the PAAD/DAPIN domain pfam02758.


Pssm-ID: 460680  Cd Length: 168  Bit Score: 278.33  E-value: 2.74e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 201 QKRPVIVKVLSTTKPFEYETPEmEKKIMFHATVATQTQFFHVKVLNTSLKEKFNGKKIIIISDYLEYDSLLEVNEESTVS 280
Cdd:pfam02760   1 QKGPKEVMVLKATEPFEYESQE-GKKKMFHATVATESEFFRVKVFNINLKEKFIPKKVIAISDYFGRNGFLEVNEASSVS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 281 EAGPNQTFEVPNKIINRAKETLKIDILHKQASGNIVYGVFMLHKKTVNQKTTIYEIQDDRGKMDVVGTGQCHNIPCEEGD 360
Cdd:pfam02760  80 EAGPDQKMEVPKSIIRKANETPKINKLKKQPSGTIVNGLFTVHKKTVNKKNTIYEIQDNTGKMEVVVYGKLTNIKCEEGD 159


                  ....*....
gi 1424027871 361 KLQLFCFRL 369
Cdd:pfam02760 160 KLRLFCFEL 168
HIN pfam02760
HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per ...
 574-740 3.39e-89

HIN-200/IF120x domain; This domain has no know function. It is found in one or two copies per protein, and is found associated with the PAAD/DAPIN domain pfam02758.


Pssm-ID: 460680  Cd Length: 168  Bit Score: 277.94  E-value: 3.39e-89
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 574 QSDLKEVMVLNATESFVYE-PKEQKKMFHATVATENEVFRVKVFNIDLKEKFTPKKIIAIANYVCRNGFLEVYPFTLVAD 652
Cdd:pfam02760   1 QKGPKEVMVLKATEPFEYEsQEGKKKMFHATVATESEFFRVKVFNINLKEKFIPKKVIAISDYFGRNGFLEVNEASSVSE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 653 VNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDK 732
Cdd:pfam02760  81 AGPDQKMEVPKSIIRKANETPKINKLKKQPSGTIVNGLFTVHKKTVNKKNTIYEIQDNTGKMEVVVYGKLTNIKCEEGDK 160


                  ....*...
gi 1424027871 733 LKLTCFEL 740
Cdd:pfam02760 161 LRLFCFEL 168
Pyrin cd08305
Pyrin: a protein-protein interaction domain; The Pyrin domain (or PYD), also called DAPIN or ...
 10-83 2.38e-32

Pyrin: a protein-protein interaction domain; The Pyrin domain (or PYD), also called DAPIN or PAAD, is a subfamily of the Death Domain (DD) superfamily and it functions in several signaling pathways. The Pyrin domain is found at the N-terminus of a variety of proteins and serves as a linker that recruits other domains into signaling complexes. Pyrin-containing proteins include NALPs, ASC (Apoptosis-associated speck-like protein containing a CARD), and the interferon-inducible p200 (IFI-200) family of proteins which includes the human IFI-16, myeloid cell nuclear differentiation antigen (MNDA) and absent in melanoma (AIM) 2. NALPs are members of the NBS-LRR family of proteins possessing a tripartite domain structure including a C-terminal LRR (leucine-rich repeats), a central nucleotide-binding site (NBS) domain or NACHT (for neuronal apoptosis inhibitor protein, CIITA, HET-E and TP1), and an N-terminal protein-protein interaction domain, which is a Pyrin domain in the case of NALPs. ASC and NALPs are involved in the regulation of inflammation. ASC, NALP1 and NALP3 are involved in the assembly of the 'inflammasome', a multiprotein platform which is formed in response to infection or injury and is responsible for caspase-1 activation and regulation of IL-1beta maturation. NALP12 functions as a negative regulator of inflammation. The p200 proteins are involved in the regulation of cell cycle and differentiation. In general, DDs are protein-protein interaction domains found in a variety of domain architectures. Their common feature is that they form homodimers by self-association or heterodimers by associating with other members of the DD superfamily including Caspase activation and recruitment domain (CARD) and Death Effector Domain (DED). They serve as adaptors in signaling pathways and can recruit other proteins into signaling complexes.


Pssm-ID: 260019  Cd Length: 73  Bit Score: 119.72  E-value: 2.38e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1424027871  10 LLKGLEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPtLEDLAETLK 83
Cdd:cd08305     1 LLTGLENITDEEFKMFKSLLASELKLTRKMQEEYDRIEIADLMEEKFGEDAGLDKLIEVFEDMP-LRSLANQLQ 73
PYRIN pfam02758
PAAD/DAPIN/Pyrin domain; This domain is predicted to contain 6 alpha helices and to have the ...
 10-80 1.94e-15

PAAD/DAPIN/Pyrin domain; This domain is predicted to contain 6 alpha helices and to have the same fold as the pfam00531 domain. This similarity may mean that this is a protein-protein interaction domain.


Pssm-ID: 460678  Cd Length: 76  Bit Score: 71.47  E-value: 1.94e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1424027871  10 LLKGLEVINDYHFRMVKSLLSNDLKLNL------KMrEEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPtLEDLAE 80
Cdd:pfam02758   2 LLWYLEELSEEEFKKFKSLLEDEPEEGLrsiprgKL-EKADRLDLADLLVEHYGEDAAVDVTIEILKKIN-LKDLAE 76
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 100-215 2.20e-04

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 45.07  E-value: 2.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871 100 KEVDATSPAPSTSSTVKTEGAEATPGAQKRKKS-----TKEKAGPKGSKVSEEQTQPPSPAGAGMSTAMGRSPSPK-TSL 173
Cdd:PTZ00449  538 KESDEPKEGGKPGETKEGEVGKKPGPAKEHKPSkiptlSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKlPEL 617

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1424027871 174 SAPPNSSSTENPKTVAKCQVTPRRNVLQKRPVIVKVLSTTKP 215
Cdd:PTZ00449  618 LDIPKSPKRPESPKSPKRPPPPQRPSSPERPEGPKIIKSPKP 659
PRK13335 PRK13335
superantigen-like protein SSL3; Reviewed;
79-190 1.09e-03

superantigen-like protein SSL3; Reviewed;


Pssm-ID: 139494 [Multi-domain]  Cd Length: 356  Bit Score: 42.04  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1424027871  79 AETLKKEKLKvKGPALSRKRKKEVDATSPAPSTSSTVKTEGAEATPGAQKRKKSTKEKAG----------PKGSKVSEEQ 148
Cdd:PRK13335   30 AEKIQSTKVD-KVPTLKAERLAMINITAGANSATTQAANTRQERTPKLEKAPNTNEEKTSaskiekisqpKQEEQKSLNI 108

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 1424027871 149 TQPPSPAGAgMSTAMGRSPSPKTSLSAPPnSSSTENPKTVAK 190
Cdd:PRK13335  109 SATPAPKQE-QSQTTTESTTPKTKVTTPP-STNTPQPMQSTK 148
PHA03058 PHA03058
Hypothetical protein; Provisional
 14-84 8.60e-03

Hypothetical protein; Provisional


Pssm-ID: 222966  Cd Length: 124  Bit Score: 37.08  E-value: 8.60e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1424027871  14 LEVINDYHFRMVKSLLSNDLKLNLKMREEYDKIQIADLMEEKFRGDAGLGKLIKIFEDIPTLEDLAETLKK 84
Cdd:PHA03058   11 LENLTDYQFKMLIFLTQDDLNIEEEEKEKLDRIDLAEKISEKYPGIRSIYFLKKVISEIPNTEYVDSLLSR 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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