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Conserved domains on  [gi|1392113037|ref|NP_001350674|]
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solute carrier family 4 member 11 isoform 4 [Homo sapiens]

Protein Classification

sodium bicarbonate transporter family protein( domain architecture ID 10469757)

sodium bicarbonate transporter family protein similar to Homo sapiens sodium bicarbonate transporter-like protein 11 that plays an important role in sodium-mediated fluid transport in different organs

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
HCO3_cotransp pfam00955
HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange ...
325-780 8.40e-165

HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange CL-/HCO3-. This family also includes cotransporters of Na+/HCO3-.


:

Pssm-ID: 460009  Cd Length: 497  Bit Score: 487.80  E-value: 8.40e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 325 PFGkGIREDIARRFPLYPLDFTDGIigknkaVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAI--------------- 389
Cdd:pfam00955   2 LFG-GLINDIKRRYPHYLSDFTDAL------NLQCLASIIFLYFACLSPAITFGGLLGDATDGYIgvsesilsqaiggii 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 390 -----------------------VIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISI 446
Cdd:pfam00955  75 falfagqpltilgstgpllvfekILFKFCKDNGLDYLSFRAWIGLWLAFFLLLLVAFDASFLVRYITRFTEEIFALLISL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 447 TFVLDAVKGTVKIFwKYYYGHYLDDYHTKRTSSLVSLSGlgASLNASLHTALNASFLASPTE---------LPSATHSGQ 517
Cdd:pfam00955 155 IFIYEAFKKLIKIF-KKYPLYLNYDCTCVPPSSNNTTNS--TLSLSTESSSINWSSLLTNSEctesyggtlVGSGCGYVP 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 518 ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEM----SKFRYNPSESPFAM 593
Cdd:pfam00955 232 DTALLSLILFLGTFWLAYFLKQFKNSPFFPTKVRRLISDFAVPIAILIMVLVDYFLGVYTPKlqvpSGFKPTRPDRGWII 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 594 AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPL 673
Cdd:pfam00955 312 NPFGKNPWWLILAAILPALLVTILIFMDQQITAVIVNRKENKLKKGSGYHLDLFVVAILNGICSLFGLPWMVAATVRSIT 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 674 HVRALALVEERVENGhIYDTIVNVKETRLTSLGAsVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVAL 753
Cdd:pfam00955 392 HVNSLKVESECVAPG-EKPKILGVREQRVTGLLV-FILIGLSVFMTPVLKLIPMPVLYGVFLYMGVTSLSGIQFFDRILL 469
                         490       500
                  ....*....|....*....|....*..
gi 1392113037 754 LLKEQTAYPPTHYIRRVPQRKIHYFTG 780
Cdd:pfam00955 470 LFMPQKHQPDTHYLRHVPLRKVHLFTL 496
PtsN super family cl43506
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
206-284 7.94e-05

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


The actual alignment was detected with superfamily member COG1762:

Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 43.69  E-value: 7.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 206 KALQKRHVCISRLVRPQNWGENSCE-VRFVILVLAPPKmkSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVH 284
Cdd:COG1762    71 EGVKKPGIAVARLKEPVDFGAMDGEpVDLVFLLAAPED--DSEEHLKLLAELARLLSDEEFREKLLNAKSPEEILELLKE 148
 
Name Accession Description Interval E-value
HCO3_cotransp pfam00955
HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange ...
325-780 8.40e-165

HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange CL-/HCO3-. This family also includes cotransporters of Na+/HCO3-.


Pssm-ID: 460009  Cd Length: 497  Bit Score: 487.80  E-value: 8.40e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 325 PFGkGIREDIARRFPLYPLDFTDGIigknkaVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAI--------------- 389
Cdd:pfam00955   2 LFG-GLINDIKRRYPHYLSDFTDAL------NLQCLASIIFLYFACLSPAITFGGLLGDATDGYIgvsesilsqaiggii 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 390 -----------------------VIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISI 446
Cdd:pfam00955  75 falfagqpltilgstgpllvfekILFKFCKDNGLDYLSFRAWIGLWLAFFLLLLVAFDASFLVRYITRFTEEIFALLISL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 447 TFVLDAVKGTVKIFwKYYYGHYLDDYHTKRTSSLVSLSGlgASLNASLHTALNASFLASPTE---------LPSATHSGQ 517
Cdd:pfam00955 155 IFIYEAFKKLIKIF-KKYPLYLNYDCTCVPPSSNNTTNS--TLSLSTESSSINWSSLLTNSEctesyggtlVGSGCGYVP 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 518 ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEM----SKFRYNPSESPFAM 593
Cdd:pfam00955 232 DTALLSLILFLGTFWLAYFLKQFKNSPFFPTKVRRLISDFAVPIAILIMVLVDYFLGVYTPKlqvpSGFKPTRPDRGWII 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 594 AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPL 673
Cdd:pfam00955 312 NPFGKNPWWLILAAILPALLVTILIFMDQQITAVIVNRKENKLKKGSGYHLDLFVVAILNGICSLFGLPWMVAATVRSIT 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 674 HVRALALVEERVENGhIYDTIVNVKETRLTSLGAsVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVAL 753
Cdd:pfam00955 392 HVNSLKVESECVAPG-EKPKILGVREQRVTGLLV-FILIGLSVFMTPVLKLIPMPVLYGVFLYMGVTSLSGIQFFDRILL 469
                         490       500
                  ....*....|....*....|....*..
gi 1392113037 754 LLKEQTAYPPTHYIRRVPQRKIHYFTG 780
Cdd:pfam00955 470 LFMPQKHQPDTHYLRHVPLRKVHLFTL 496
ae TIGR00834
anion exchange protein; The Anion Exchanger (AE) Family (TC 2.A.31)Characterized protein ...
231-834 1.79e-74

anion exchange protein; The Anion Exchanger (AE) Family (TC 2.A.31)Characterized protein members of the AE family are found only in animals.They preferentially catalyze anion exchange (antiport) reactions, typically acting as HCO3-:Cl- antiporters, but also transporting a range of other inorganic and organic anions. Additionally, renal Na+:HCO3- cotransporters have been found to be members of the AE family. They catalyze the reabsorption of HCO3- in the renal proximal tubule. [Transport and binding proteins, Anions]


Pssm-ID: 273290 [Multi-domain]  Cd Length: 900  Bit Score: 261.24  E-value: 1.79e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 231 VRFVILVLAP--PKMKSTktamEVARTFATMFSDIAF---------RQKLLETRTE---------------EEFKEALVH 284
Cdd:TIGR00834 220 VRFLFVLLGPsgPGKDYH----EIGRAIATLMSDEVFhdaayladdRDDLLAGIDEfldcsivlppgewdpEIRLEPPAP 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 285 -QRQLL-------TMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIReDIARRFPLYPLDFTDGIigkNKAV 356
Cdd:TIGR00834 296 lQRELLrkryepsTVRPENPTMGGDTEPEDGGSEGPHGDDDPLQRTGRPFGGLIR-DIKRRYPHYLSDFTDAL---NPQC 371
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 357 gkyITTTLFLYFACLLPTIAFGSLNDENTDGAI----------VIRVI----------------------------CDDY 398
Cdd:TIGR00834 372 ---LAAVIFIYFAALSPAITFGGLLGEKTRNMMgvsellistaVQGVLfallaaqpllvvgfsgpllvfeeaffsfCESN 448
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 399 DLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFwkyyyghylDDYHTKRTS 478
Cdd:TIGR00834 449 GLEYLVGRVWIGLWLVLLVLLLVATEGSFLVRYISRFTQEIFSFLISLIFIYETFSKLIKIF---------QEHPLQVFY 519
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 479 -SLVSLSGLGASLNASLHTALNASfLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDC 557
Cdd:TIGR00834 520 nTLFCVPPKPQGPSVSALLEKDCS-KLGGTLGGNNCRFQPNTALLSLVLMLGTFFLAMFLRKFKNSRYFPGKARRLIGDF 598
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 558 ALPIAVLAFSLISS-------------HGFREIEMSKFRY--NP--SESPFAMAQIQSLSLRAVsgamglgfLLSMLFFI 620
Cdd:TIGR00834 599 GVPISILIMVLVDIfigdtytqklsvpSGLKVTNPSARGWfiPPlgENRPFPWWMMFAAALPAL--------LVFILIFM 670
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 621 EQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDtIVNVKET 700
Cdd:TIGR00834 671 EQQITTLIVSKKERKLKKGSGFHLDLLLVVGMGGVAALFGLPWLSAATVRSVTHANALTVMSKASAPGEKAQ-IQEVREQ 749
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 701 RLTSLGASVLVGLSLLLLPVPLQwIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTG 780
Cdd:TIGR00834 750 RVTGLLVAVLVGLSILMEPILKR-IPLAVLFGIFLYMGVTSLSGIQLFDRLLLLLMPPKYHPDVPYVRRVKTWRMHLFTA 828
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1392113037 781 LQVLQLLLLCAFGMSSlpyMKMIFPLIMIAMIPIRYILLPRI---IEAKYLDVMDAE 834
Cdd:TIGR00834 829 IQILCLALLWVVKSTP---ASLAFPFVLILTVPLRRLLLPRLfteRELKCLDKEDAK 882
PtsN COG1762
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
206-284 7.94e-05

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 43.69  E-value: 7.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 206 KALQKRHVCISRLVRPQNWGENSCE-VRFVILVLAPPKmkSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVH 284
Cdd:COG1762    71 EGVKKPGIAVARLKEPVDFGAMDGEpVDLVFLLAAPED--DSEEHLKLLAELARLLSDEEFREKLLNAKSPEEILELLKE 148
 
Name Accession Description Interval E-value
HCO3_cotransp pfam00955
HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange ...
325-780 8.40e-165

HCO3- transporter family; This family contains Band 3 anion exchange proteins that exchange CL-/HCO3-. This family also includes cotransporters of Na+/HCO3-.


Pssm-ID: 460009  Cd Length: 497  Bit Score: 487.80  E-value: 8.40e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 325 PFGkGIREDIARRFPLYPLDFTDGIigknkaVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAI--------------- 389
Cdd:pfam00955   2 LFG-GLINDIKRRYPHYLSDFTDAL------NLQCLASIIFLYFACLSPAITFGGLLGDATDGYIgvsesilsqaiggii 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 390 -----------------------VIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISI 446
Cdd:pfam00955  75 falfagqpltilgstgpllvfekILFKFCKDNGLDYLSFRAWIGLWLAFFLLLLVAFDASFLVRYITRFTEEIFALLISL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 447 TFVLDAVKGTVKIFwKYYYGHYLDDYHTKRTSSLVSLSGlgASLNASLHTALNASFLASPTE---------LPSATHSGQ 517
Cdd:pfam00955 155 IFIYEAFKKLIKIF-KKYPLYLNYDCTCVPPSSNNTTNS--TLSLSTESSSINWSSLLTNSEctesyggtlVGSGCGYVP 231
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 518 ATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLISSHGFREIEM----SKFRYNPSESPFAM 593
Cdd:pfam00955 232 DTALLSLILFLGTFWLAYFLKQFKNSPFFPTKVRRLISDFAVPIAILIMVLVDYFLGVYTPKlqvpSGFKPTRPDRGWII 311
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 594 AQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPL 673
Cdd:pfam00955 312 NPFGKNPWWLILAAILPALLVTILIFMDQQITAVIVNRKENKLKKGSGYHLDLFVVAILNGICSLFGLPWMVAATVRSIT 391
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 674 HVRALALVEERVENGhIYDTIVNVKETRLTSLGAsVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVAL 753
Cdd:pfam00955 392 HVNSLKVESECVAPG-EKPKILGVREQRVTGLLV-FILIGLSVFMTPVLKLIPMPVLYGVFLYMGVTSLSGIQFFDRILL 469
                         490       500
                  ....*....|....*....|....*..
gi 1392113037 754 LLKEQTAYPPTHYIRRVPQRKIHYFTG 780
Cdd:pfam00955 470 LFMPQKHQPDTHYLRHVPLRKVHLFTL 496
ae TIGR00834
anion exchange protein; The Anion Exchanger (AE) Family (TC 2.A.31)Characterized protein ...
231-834 1.79e-74

anion exchange protein; The Anion Exchanger (AE) Family (TC 2.A.31)Characterized protein members of the AE family are found only in animals.They preferentially catalyze anion exchange (antiport) reactions, typically acting as HCO3-:Cl- antiporters, but also transporting a range of other inorganic and organic anions. Additionally, renal Na+:HCO3- cotransporters have been found to be members of the AE family. They catalyze the reabsorption of HCO3- in the renal proximal tubule. [Transport and binding proteins, Anions]


Pssm-ID: 273290 [Multi-domain]  Cd Length: 900  Bit Score: 261.24  E-value: 1.79e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 231 VRFVILVLAP--PKMKSTktamEVARTFATMFSDIAF---------RQKLLETRTE---------------EEFKEALVH 284
Cdd:TIGR00834 220 VRFLFVLLGPsgPGKDYH----EIGRAIATLMSDEVFhdaayladdRDDLLAGIDEfldcsivlppgewdpEIRLEPPAP 295
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 285 -QRQLL-------TMVSHGPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGKGIReDIARRFPLYPLDFTDGIigkNKAV 356
Cdd:TIGR00834 296 lQRELLrkryepsTVRPENPTMGGDTEPEDGGSEGPHGDDDPLQRTGRPFGGLIR-DIKRRYPHYLSDFTDAL---NPQC 371
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 357 gkyITTTLFLYFACLLPTIAFGSLNDENTDGAI----------VIRVI----------------------------CDDY 398
Cdd:TIGR00834 372 ---LAAVIFIYFAALSPAITFGGLLGEKTRNMMgvsellistaVQGVLfallaaqpllvvgfsgpllvfeeaffsfCESN 448
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 399 DLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFwkyyyghylDDYHTKRTS 478
Cdd:TIGR00834 449 GLEYLVGRVWIGLWLVLLVLLLVATEGSFLVRYISRFTQEIFSFLISLIFIYETFSKLIKIF---------QEHPLQVFY 519
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 479 -SLVSLSGLGASLNASLHTALNASfLASPTELPSATHSGQATAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDC 557
Cdd:TIGR00834 520 nTLFCVPPKPQGPSVSALLEKDCS-KLGGTLGGNNCRFQPNTALLSLVLMLGTFFLAMFLRKFKNSRYFPGKARRLIGDF 598
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 558 ALPIAVLAFSLISS-------------HGFREIEMSKFRY--NP--SESPFAMAQIQSLSLRAVsgamglgfLLSMLFFI 620
Cdd:TIGR00834 599 GVPISILIMVLVDIfigdtytqklsvpSGLKVTNPSARGWfiPPlgENRPFPWWMMFAAALPAL--------LVFILIFM 670
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 621 EQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDtIVNVKET 700
Cdd:TIGR00834 671 EQQITTLIVSKKERKLKKGSGFHLDLLLVVGMGGVAALFGLPWLSAATVRSVTHANALTVMSKASAPGEKAQ-IQEVREQ 749
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 701 RLTSLGASVLVGLSLLLLPVPLQwIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTG 780
Cdd:TIGR00834 750 RVTGLLVAVLVGLSILMEPILKR-IPLAVLFGIFLYMGVTSLSGIQLFDRLLLLLMPPKYHPDVPYVRRVKTWRMHLFTA 828
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1392113037 781 LQVLQLLLLCAFGMSSlpyMKMIFPLIMIAMIPIRYILLPRI---IEAKYLDVMDAE 834
Cdd:TIGR00834 829 IQILCLALLWVVKSTP---ASLAFPFVLILTVPLRRLLLPRLfteRELKCLDKEDAK 882
PtsN COG1762
Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate ...
206-284 7.94e-05

Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) [Carbohydrate transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 441368 [Multi-domain]  Cd Length: 150  Bit Score: 43.69  E-value: 7.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1392113037 206 KALQKRHVCISRLVRPQNWGENSCE-VRFVILVLAPPKmkSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVH 284
Cdd:COG1762    71 EGVKKPGIAVARLKEPVDFGAMDGEpVDLVFLLAAPED--DSEEHLKLLAELARLLSDEEFREKLLNAKSPEEILELLKE 148
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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