synaptobrevin homolog YKT6 isoform 2 [Homo sapiens]
longin domain-containing protein( domain architecture ID 13000503)
longin domain-containing protein similar to R-SNARE subgroup proteins, including VAMP7, Ykt6, and Sec22 which is required for transporting proteins from the ER to the plasma membrane, via the Golgi apparatus
List of domain hits
Name | Accession | Description | Interval | E-value | |||
Longin | cd14824 | longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including ... |
4-130 | 2.69e-29 | |||
longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including VAMP7, Ykt6, and Sec22. Longin is one of the approximately 26 components required for transporting proteins from the ER to the plasma membrane, via the Golgi apparatus. It is necessary for the steps of the transfer from the ER to the Golgi complex. Longins are the only R-SNAREs that are common to all eukaryotes, and they are characterized by a conserved N-terminal domain with a profilin-like fold called a longin domain. : Pssm-ID: 341428 Cd Length: 122 Bit Score: 103.87 E-value: 2.69e-29
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SNARE super family | cl22856 | SNARE motif; SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) ... |
136-153 | 1.64e-06 | |||
SNARE motif; SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins consist of coiled-coil helices (called SNARE motifs) which mediate the interactions between SNARE proteins, and a transmembrane domain. The SNARE complex mediates membrane fusion, important for trafficking of newly synthesized proteins, recycling of pre-existing proteins and organelle formation. SNARE proteins are classified into four groups, Qa-, Qb-, Qc- and R-SNAREs, depending on whether the residue in the hydrophilic center layer of the four-helical bundle is a glutamine (Q) or arginine (R). Qa-, Qb- and Qc-SNAREs are localized to target organelle membranes, while R-SNARE is localized to vesicle membranes. They form unique complexes consisting of one member of each subgroup, that mediate fusion between a specific type of vesicles and their target organelle. Their SNARE motifs form twisted and parallel heterotetrameric helix bundles. The actual alignment was detected with superfamily member cd15867: Pssm-ID: 473982 Cd Length: 61 Bit Score: 43.13 E-value: 1.64e-06
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Name | Accession | Description | Interval | E-value | |||
Longin | cd14824 | longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including ... |
4-130 | 2.69e-29 | |||
longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including VAMP7, Ykt6, and Sec22. Longin is one of the approximately 26 components required for transporting proteins from the ER to the plasma membrane, via the Golgi apparatus. It is necessary for the steps of the transfer from the ER to the Golgi complex. Longins are the only R-SNAREs that are common to all eukaryotes, and they are characterized by a conserved N-terminal domain with a profilin-like fold called a longin domain. Pssm-ID: 341428 Cd Length: 122 Bit Score: 103.87 E-value: 2.69e-29
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Longin | pfam13774 | Regulated-SNARE-like domain; Longin is one of the approximately 26 components required for ... |
44-115 | 2.24e-19 | |||
Regulated-SNARE-like domain; Longin is one of the approximately 26 components required for transporting proteins from the ER to the plasma membrane, via the Golgi apparatus. It is necessary for the steps of the transfer from the ER to the Golgi complex. Longins are the only R-SNAREs that are common to all eukaryotes, and they are characterized by a conserved N-terminal domain with a profilin-like fold called a longin domain. Pssm-ID: 463978 Cd Length: 81 Bit Score: 77.19 E-value: 2.24e-19
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SNC1 | COG5143 | Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]; |
3-155 | 5.14e-18 | |||
Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]; Pssm-ID: 227472 [Multi-domain] Cd Length: 190 Bit Score: 76.70 E-value: 5.14e-18
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R-SNARE_YKT6 | cd15867 | SNARE motif of YKT6; Ykt6 forms complexes with syntaxin-5 (Qa), GS28 (Qb) and either Bet1 (Qc) ... |
136-153 | 1.64e-06 | |||
SNARE motif of YKT6; Ykt6 forms complexes with syntaxin-5 (Qa), GS28 (Qb) and either Bet1 (Qc) or GS15 (Qc). This complex regulates the early secretory pathway of eukaryotic cells at the level of the transport from the ER-Golgi intermediate compartment (ERGIC) to the cis-Golgi and transport from the trans-Golgi network to the cis-Golgi, respectively. Ykt6 is a member of the R-SNARE subfamily of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins which contain coiled-coil helices (called SNARE motifs) that mediate the interactions between SNARE proteins, and a transmembrane domain. The SNARE complex mediates membrane fusion, important for trafficking of newly synthesized proteins, recycling of pre-existing proteins and organelle formation. SNARE proteins are classified into four groups, Qa-, Qb-, Qc- and R-SNAREs, depending on whether the residue in the hydrophilic center layer of the four-helical bundle is a glutamine (Q) or arginine (R). Qa-, as well as Qb- and Qc-SNAREs, are localized to target organelle membranes, while R-SNARE is localized to vesicle membranes. They form unique complexes consisting of one member of each subgroup, that mediate fusion between a specific type of vesicles and their target organelle. Their SNARE motifs form twisted and parallel heterotetrameric helix bundles. Pssm-ID: 277220 Cd Length: 61 Bit Score: 43.13 E-value: 1.64e-06
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Name | Accession | Description | Interval | E-value | |||
Longin | cd14824 | longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including ... |
4-130 | 2.69e-29 | |||
longin domain; Longin-domain is N-terminal domain of a subgroup of R-SNARE proteins, including VAMP7, Ykt6, and Sec22. Longin is one of the approximately 26 components required for transporting proteins from the ER to the plasma membrane, via the Golgi apparatus. It is necessary for the steps of the transfer from the ER to the Golgi complex. Longins are the only R-SNAREs that are common to all eukaryotes, and they are characterized by a conserved N-terminal domain with a profilin-like fold called a longin domain. Pssm-ID: 341428 Cd Length: 122 Bit Score: 103.87 E-value: 2.69e-29
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Longin | pfam13774 | Regulated-SNARE-like domain; Longin is one of the approximately 26 components required for ... |
44-115 | 2.24e-19 | |||
Regulated-SNARE-like domain; Longin is one of the approximately 26 components required for transporting proteins from the ER to the plasma membrane, via the Golgi apparatus. It is necessary for the steps of the transfer from the ER to the Golgi complex. Longins are the only R-SNAREs that are common to all eukaryotes, and they are characterized by a conserved N-terminal domain with a profilin-like fold called a longin domain. Pssm-ID: 463978 Cd Length: 81 Bit Score: 77.19 E-value: 2.24e-19
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SNC1 | COG5143 | Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]; |
3-155 | 5.14e-18 | |||
Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]; Pssm-ID: 227472 [Multi-domain] Cd Length: 190 Bit Score: 76.70 E-value: 5.14e-18
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R-SNARE_YKT6 | cd15867 | SNARE motif of YKT6; Ykt6 forms complexes with syntaxin-5 (Qa), GS28 (Qb) and either Bet1 (Qc) ... |
136-153 | 1.64e-06 | |||
SNARE motif of YKT6; Ykt6 forms complexes with syntaxin-5 (Qa), GS28 (Qb) and either Bet1 (Qc) or GS15 (Qc). This complex regulates the early secretory pathway of eukaryotic cells at the level of the transport from the ER-Golgi intermediate compartment (ERGIC) to the cis-Golgi and transport from the trans-Golgi network to the cis-Golgi, respectively. Ykt6 is a member of the R-SNARE subfamily of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins which contain coiled-coil helices (called SNARE motifs) that mediate the interactions between SNARE proteins, and a transmembrane domain. The SNARE complex mediates membrane fusion, important for trafficking of newly synthesized proteins, recycling of pre-existing proteins and organelle formation. SNARE proteins are classified into four groups, Qa-, Qb-, Qc- and R-SNAREs, depending on whether the residue in the hydrophilic center layer of the four-helical bundle is a glutamine (Q) or arginine (R). Qa-, as well as Qb- and Qc-SNAREs, are localized to target organelle membranes, while R-SNARE is localized to vesicle membranes. They form unique complexes consisting of one member of each subgroup, that mediate fusion between a specific type of vesicles and their target organelle. Their SNARE motifs form twisted and parallel heterotetrameric helix bundles. Pssm-ID: 277220 Cd Length: 61 Bit Score: 43.13 E-value: 1.64e-06
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Blast search parameters | ||||
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