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Conserved domains on  [gi|1390157559|ref|NP_001350376|]
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RCC1-like G exchanging factor-like protein isoform 4 [Homo sapiens]

Protein Classification

ATS1 family protein( domain architecture ID 11474102)

ATS1 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 45-322 1.30e-38

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 139.73  E-value: 1.30e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559  45 QVSCGRAHSLVLTDREGVFSMGNNSYGQCGrkvveNEIYSESHRVHRMQDFDGqVVQVACGQDHSLFLTDKGEVYSCGWG 124
Cdd:COG5184     2 QVAAGGSHSCALKSDGTVWCWGDNSYGQLG-----DGTTTDRSTPVRVPGLSN-VVAVAAGGDHTCALKADGTVWCWGNN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 125 ADGQTGLGHYNITSSPTKLGGdlaGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASvTDSTQVNVPRcLHFSGVGK 204
Cdd:COG5184    76 SYGQLGDGTTTDRTTPVKVPG---LTGVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGD-GTTTNRLTPV-QVDAGLSG 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 205 VRQAACGG-TGCAVLNGeGHVFVWG---YGILGKGpNLVESAVPEMIPptlfGLTEfnpeiqVSRIRCGLSHFAALTNKG 280
Cdd:COG5184   151 VVAIAAGGyHTCALKSD-GTVWCWGansYGQLGDG-TTTDRPTPVQVG----GLSG------VVAVAAGGDHSCALKSDG 218

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1390157559 281 ELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDH 322
Cdd:COG5184   219 TVWCWGSNSSGQLGDGTTTDRATPVQVAGLTGVVAIAAGGSH 260
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 45-322 1.30e-38

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 139.73  E-value: 1.30e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559  45 QVSCGRAHSLVLTDREGVFSMGNNSYGQCGrkvveNEIYSESHRVHRMQDFDGqVVQVACGQDHSLFLTDKGEVYSCGWG 124
Cdd:COG5184     2 QVAAGGSHSCALKSDGTVWCWGDNSYGQLG-----DGTTTDRSTPVRVPGLSN-VVAVAAGGDHTCALKADGTVWCWGNN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 125 ADGQTGLGHYNITSSPTKLGGdlaGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASvTDSTQVNVPRcLHFSGVGK 204
Cdd:COG5184    76 SYGQLGDGTTTDRTTPVKVPG---LTGVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGD-GTTTNRLTPV-QVDAGLSG 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 205 VRQAACGG-TGCAVLNGeGHVFVWG---YGILGKGpNLVESAVPEMIPptlfGLTEfnpeiqVSRIRCGLSHFAALTNKG 280
Cdd:COG5184   151 VVAIAAGGyHTCALKSD-GTVWCWGansYGQLGDG-TTTDRPTPVQVG----GLSG------VVAVAAGGDHSCALKSDG 218

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1390157559 281 ELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDH 322
Cdd:COG5184   219 TVWCWGSNSSGQLGDGTTTDRATPVQVAGLTGVVAIAAGGSH 260
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
99-128 9.90e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 47.42  E-value: 9.90e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 1390157559  99 VVQVACGQDHSLFLTDKGEVYSCGWGADGQ 128
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 45-322 1.30e-38

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 139.73  E-value: 1.30e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559  45 QVSCGRAHSLVLTDREGVFSMGNNSYGQCGrkvveNEIYSESHRVHRMQDFDGqVVQVACGQDHSLFLTDKGEVYSCGWG 124
Cdd:COG5184     2 QVAAGGSHSCALKSDGTVWCWGDNSYGQLG-----DGTTTDRSTPVRVPGLSN-VVAVAAGGDHTCALKADGTVWCWGNN 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 125 ADGQTGLGHYNITSSPTKLGGdlaGVNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASvTDSTQVNVPRcLHFSGVGK 204
Cdd:COG5184    76 SYGQLGDGTTTDRTTPVKVPG---LTGVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGD-GTTTNRLTPV-QVDAGLSG 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 205 VRQAACGG-TGCAVLNGeGHVFVWG---YGILGKGpNLVESAVPEMIPptlfGLTEfnpeiqVSRIRCGLSHFAALTNKG 280
Cdd:COG5184   151 VVAIAAGGyHTCALKSD-GTVWCWGansYGQLGDG-TTTDRPTPVQVG----GLSG------VVAVAAGGDHSCALKSDG 218

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1390157559 281 ELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDH 322
Cdd:COG5184   219 TVWCWGSNSSGQLGDGTTTDRATPVQVAGLTGVVAIAAGGSH 260
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 29-327 6.19e-37

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 135.49  E-value: 6.19e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559  29 SPVSLPLDRPQETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGrkvveNEIYSESHRVHRMQDFDGqVVQVACGQDH 108
Cdd:COG5184    36 TDRSTPVRVPGLSNVVAVAAGGDHTCALKADGTVWCWGNNSYGQLG-----DGTTTDRTTPVKVPGLTG-VVAVAAGYYH 109

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 109 SLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAgvNVIQVATYGDCCLAVSADGGLFGWGNSEYLQLASVTdS 188
Cdd:COG5184   110 SCALKSDGTVWCWGDNSSGQLGDGTTTNRLTPVQVDAGLS--GVVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGT-T 186

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 189 TQVNVPRclHFSGVGKVRQAACGG-TGCAVLNGeGHVFVWG---YGILGKGPNlVESAVPEMIPptlfGLTefnpeiQVS 264
Cdd:COG5184   187 TDRPTPV--QVGGLSGVVAVAAGGdHSCALKSD-GTVWCWGsnsSGQLGDGTT-TDRATPVQVA----GLT------GVV 252

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1390157559 265 RIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDHmvTLA 327
Cdd:COG5184   253 AIAAGGSHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLSGVVAVAAGSSH--TCA 313
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 27-304 4.73e-34

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 127.79  E-value: 4.73e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559  27 EPSPVSLPLDrpqeTRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRkvveneiYSESHRVHRMQDFDGQ--VVQVAC 104
Cdd:COG5184    88 RTTPVKVPGL----TGVVAVAAGYYHSCALKSDGTVWCWGDNSSGQLGD-------GTTTNRLTPVQVDAGLsgVVAIAA 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 105 GQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLagvNVIQVATYGDCCLAVSADGGLFGWGNSEYLQL-- 182
Cdd:COG5184   157 GGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLS---GVVAVAAGGDHSCALKSDGTVWCWGSNSSGQLgd 233

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 183 -ASVTDSTQVNVPrclhfsGVGKVRQAACGGT-GCAVLNGeGHVFVWG---YGILGKGpNLVESAVPEMIPptlfGLTef 257
Cdd:COG5184   234 gTTTDRATPVQVA------GLTGVVAIAAGGShTCALKSD-GTVWCWGdnsYGQLGDG-TTTDRSTPVKVP----GLS-- 299

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*..
gi 1390157559 258 npeiQVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFP 304
Cdd:COG5184   300 ----GVVAVAAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTTDRSTP 342
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 100-322 5.53e-29

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 113.92  E-value: 5.53e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 100 VQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGdlaGVNVIQVATYGDCCLAVSADGGLFGWGNSEY 179
Cdd:COG5184     1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVRVPG---LSNVVAVAAGGDHTCALKADGTVWCWGNNSY 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 180 LQL--ASVTDSTQ-VNVPrclhfsGVGKVRQAACGG-TGCAVLNGeGHVFVWG---YGILGKGPNlVESAVPEMIPPTLF 252
Cdd:COG5184    78 GQLgdGTTTDRTTpVKVP------GLTGVVAVAAGYyHSCALKSD-GTVWCWGdnsSGQLGDGTT-TNRLTPVQVDAGLS 149

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559 253 GltefnpeiqVSRIRCGLSHFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPGEPVDVACGVDH 322
Cdd:COG5184   150 G---------VVAIAAGGYHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSGVVAVAAGGDH 210
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 2-141 9.72e-12

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 65.00  E-value: 9.72e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1390157559   2 GLNKDSQLGfhrsrkdkTRGYEYVLEPSPVSLPldrpqeTRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKvvene 81
Cdd:COG5184   224 GSNSSGQLG--------DGTTTDRATPVQVAGL------TGVVAIAAGGSHTCALKSDGTVWCWGDNSYGQLGDG----- 284

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1390157559  82 iySESHRVHRMQ-DFDGQVVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPT 141
Cdd:COG5184   285 --TTTDRSTPVKvPGLSGVVAVAAGSSHTCALLTDGTVWCWGDNAYGQLGDGTTTDRSTPV 343
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
99-128 9.90e-08

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 47.42  E-value: 9.90e-08
                          10        20        30
                  ....*....|....*....|....*....|
gi 1390157559  99 VVQVACGQDHSLFLTDKGEVYSCGWGADGQ 128
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
279-322 2.38e-07

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 46.74  E-value: 2.38e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1390157559 279 KGELFVWGKNIRGCLGIGRLEDQYFPWRVTMPG--EPVDVACGVDH 322
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEGLSgnKVVQVACGGDH 46
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
168-218 3.00e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 43.66  E-value: 3.00e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1390157559 168 DGGLFGWGNSEYLQLASVTDSTQvNVPRCLHFSGVGKVRQAACGGTGCAVL 218
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENV-LVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
62-112 8.93e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 42.50  E-value: 8.93e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1390157559  62 VFSMGNNSYGQCGRKVVENEIYSEshrvhRMQDFDGQ-VVQVACGQDHSLFL 112
Cdd:pfam00415   4 VYTWGRNDYGQLGLGTTENVLVPQ-----KVEGLSGNkVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
43-72 1.31e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 41.26  E-value: 1.31e-05
                          10        20        30
                  ....*....|....*....|....*....|
gi 1390157559  43 VLQVSCGRAHSLVLTDREGVFSMGNNSYGQ 72
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
115-165 3.57e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 40.58  E-value: 3.57e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1390157559 115 KGEVYSCGWGADGQTGLGHYNITSSPTKLGGdLAGVNVIQVATYGDCCLAV 165
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEG-LSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
263-292 5.94e-04

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 36.63  E-value: 5.94e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 1390157559 263 VSRIRCGLSHFAALTNKGELFVWGKNIRGC 292
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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