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Conserved domains on  [gi|1269208377|ref|NP_001344145|]
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cilia- and flagella-associated protein 97 isoform 1 [Mus musculus]

Protein Classification

CFAP97 domain-containing protein( domain architecture ID 10620683)

CFAP97 domain-containing protein similar to vertebrate cilia- and flagella-associated protein 97 (CFAP97)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Hmw_CFAP97 pfam13879
Hemingway/CFA97; Drosophila Hemingway (Hmw) is required for motile cilia function and sperm ...
 354-456 7.83e-20

Hemingway/CFA97; Drosophila Hemingway (Hmw) is required for motile cilia function and sperm flagella assembly. The human orthologue, known as cilia- and flagella-associated protein 97 (CFAP97) or KIAA1430, localizes to the primary cilium. Another member of this family is the uncharacterized protein CFAP97D1/2 (CFAP97 domain-containing protein 1/2).


:

Pssm-ID: 464014  Cd Length: 100  Bit Score: 84.33  E-value: 7.83e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1269208377 354 LNHLLKAFLQLDKKGPQKHHfeqpaiIPRKNYSFTREEVRQIDRENQRLLKELSRQAEKPG-----SKSTIPGRSIGHPP 428
Cdd:pfam13879   1 LNKLKNAKPTVDNKAPPHLS------LKLKKLQFEEERLAEIERENQILLEKISRIMRRKGkvdknSLSTQSYSSKTRPK 74

                          90       100
                  ....*....|....*....|....*...
gi 1269208377 429 KLYhsALNRQREQQRIERENMALLKRLE 456
Cdd:pfam13879  75 SLN--AENRKRELLRIEEENQKLLKRLQ 100
 
Name Accession Description Interval E-value
Hmw_CFAP97 pfam13879
Hemingway/CFA97; Drosophila Hemingway (Hmw) is required for motile cilia function and sperm ...
 354-456 7.83e-20

Hemingway/CFA97; Drosophila Hemingway (Hmw) is required for motile cilia function and sperm flagella assembly. The human orthologue, known as cilia- and flagella-associated protein 97 (CFAP97) or KIAA1430, localizes to the primary cilium. Another member of this family is the uncharacterized protein CFAP97D1/2 (CFAP97 domain-containing protein 1/2).


Pssm-ID: 464014  Cd Length: 100  Bit Score: 84.33  E-value: 7.83e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1269208377 354 LNHLLKAFLQLDKKGPQKHHfeqpaiIPRKNYSFTREEVRQIDRENQRLLKELSRQAEKPG-----SKSTIPGRSIGHPP 428
Cdd:pfam13879   1 LNKLKNAKPTVDNKAPPHLS------LKLKKLQFEEERLAEIERENQILLEKISRIMRRKGkvdknSLSTQSYSSKTRPK 74

                          90       100
                  ....*....|....*....|....*...
gi 1269208377 429 KLYhsALNRQREQQRIERENMALLKRLE 456
Cdd:pfam13879  75 SLN--AENRKRELLRIEEENQKLLKRLQ 100
 
Name Accession Description Interval E-value
Hmw_CFAP97 pfam13879
Hemingway/CFA97; Drosophila Hemingway (Hmw) is required for motile cilia function and sperm ...
 354-456 7.83e-20

Hemingway/CFA97; Drosophila Hemingway (Hmw) is required for motile cilia function and sperm flagella assembly. The human orthologue, known as cilia- and flagella-associated protein 97 (CFAP97) or KIAA1430, localizes to the primary cilium. Another member of this family is the uncharacterized protein CFAP97D1/2 (CFAP97 domain-containing protein 1/2).


Pssm-ID: 464014  Cd Length: 100  Bit Score: 84.33  E-value: 7.83e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1269208377 354 LNHLLKAFLQLDKKGPQKHHfeqpaiIPRKNYSFTREEVRQIDRENQRLLKELSRQAEKPG-----SKSTIPGRSIGHPP 428
Cdd:pfam13879   1 LNKLKNAKPTVDNKAPPHLS------LKLKKLQFEEERLAEIERENQILLEKISRIMRRKGkvdknSLSTQSYSSKTRPK 74

                          90       100
                  ....*....|....*....|....*...
gi 1269208377 429 KLYhsALNRQREQQRIERENMALLKRLE 456
Cdd:pfam13879  75 SLN--AENRKRELLRIEEENQKLLKRLQ 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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