|
Name |
Accession |
Description |
Interval |
E-value |
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1274-1416 |
4.00e-40 |
|
Clathrin heavy chain repeat homology;
:
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 145.49 E-value: 4.00e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1274 LHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAE 1353
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1249618521 1354 QAHLWAELVFLYDKYEEYDNAIITMMNHPTDAwkeGQFKDIITKVANVELYYKAIQFYLEFKP 1416
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIEHLGNY---EKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
979-1118 |
1.57e-34 |
|
Clathrin heavy chain repeat homology;
:
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 129.32 E-value: 1.57e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 979 LSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSvfsEHRNLQNLLILTAIKADRTRVMEYI-NRLDNYDAPDIAN 1057
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNS---ENPALQTKLIELYAKYDPQKEIERLdNKSNHYDIEKVGK 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1249618521 1058 IAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQK 1118
Cdd:smart00299 78 LCEKAKLYEEAVELYKKDGNFKDAIVTLIEHLGNYEKAIEYFVKQNNPELWAEVLKALLDK 138
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1128-1265 |
5.04e-33 |
|
Clathrin heavy chain repeat homology;
:
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 125.08 E-value: 5.04e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1128 YIKADDPSSYMEVVQAANASGNWEELVKYLQMARKKARE-SYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCY 1206
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSEnPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1207 DEKMYDAAKLLYNNVSNFGRLASTLV-HLGEYQAAVDGARKANSTRTWKEVCFACVDGKE 1265
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIeHLGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
686-824 |
1.48e-32 |
|
Clathrin heavy chain repeat homology;
:
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 123.92 E-value: 1.48e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 686 ASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNF-SQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLK 764
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLnSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1249618521 765 EAKLTDQLPLIIVCDrFDFVHDLVLYLYR-NNLQKYIEIYVQKVNPSRLPVVIGGLLDVDC 824
Cdd:smart00299 81 KAKLYEEAVELYKKD-GNFKDAIVTLIEHlGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
833-968 |
6.20e-32 |
|
Clathrin heavy chain repeat homology;
:
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 122.00 E-value: 6.20e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 833 ILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNP--ERFLRENPYYDSRVVGKYCE 910
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKeiERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 911 KRDPH-LACVAYERGQCDLELINVCNENS-LFKSLSRYLVRRKDPELWGSVLLESNPYRR 968
Cdd:smart00299 81 KAKLYeEAVELYKKDGNFKDAIVTLIEHLgNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| Clathrin_H_link |
pfam13838 |
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ... |
356-421 |
6.79e-32 |
|
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.
:
Pssm-ID: 463995 Cd Length: 66 Bit Score: 119.24 E-value: 6.79e-32
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1249618521 356 NLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGIL 421
Cdd:pfam13838 1 GLPGADDLYFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYFGTL 66
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1427-1564 |
8.86e-31 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
:
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 118.90 E-value: 8.86e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1427 SPRLDHTRAVNYFSKVKQLPLVKPYLRSVQN---HNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHE 1503
Cdd:pfam00637 5 TDPIDVSRVVKLFEKAGLLEELISYLESALKedsRENPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLCEKAD 84
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1249618521 1504 LIEFRRiaaYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRE 1564
Cdd:pfam00637 85 LYEEAV---ILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
541-674 |
1.19e-29 |
|
Clathrin heavy chain repeat homology;
:
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 115.45 E-value: 1.19e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 541 EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNrPSEGPLQTRLLEMNLMHAPQVADAILGNqMFTHYDRAHIAQLCEKA 620
Cdd:smart00299 5 SDPIDVSEVVELFEKRNLLEELIPYLESALKLN-SENPALQTKLIELYAKYDPQKEIERLDN-KSNHYDIEKVGKLCEKA 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1249618521 621 GLLQRALEHFTDLYDIKRAVVHT--HLLNPEWLVNYFGS-LSVEDSLECLRAMLSAN 674
Cdd:smart00299 83 KLYEEAVELYKKDGNFKDAIVTLieHLGNYEKAIEYFVKqNNPELWAEVLKALLDKP 139
|
|
| Clathrin-link |
pfam09268 |
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of ... |
331-354 |
4.27e-10 |
|
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of alpha-alpha superhelix. They are predominantly found in clathrin, where they act as a heavy-chain linker domain.
:
Pssm-ID: 462732 Cd Length: 24 Bit Score: 55.91 E-value: 4.27e-10
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
198-234 |
2.95e-07 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
:
Pssm-ID: 460192 Cd Length: 37 Bit Score: 48.18 E-value: 2.95e-07
10 20 30
....*....|....*....|....*....|....*..
gi 1249618521 198 AASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVG 234
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTKKGQVQIVDVE 37
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
256-288 |
4.89e-05 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
:
Pssm-ID: 460192 Cd Length: 37 Bit Score: 42.02 E-value: 4.89e-05
10 20 30
....*....|....*....|....*....|...
gi 1249618521 256 AQNDFPVAMQISEKHDVVFLITKYGYIHLYDLE 288
Cdd:pfam01394 5 AIIIFPTATMESWLFIIAINGTKKGQVQIVDVE 37
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
19-56 |
4.94e-05 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
:
Pssm-ID: 460192 Cd Length: 37 Bit Score: 42.02 E-value: 4.94e-05
10 20 30
....*....|....*....|....*....|....*...
gi 1249618521 19 GINPANIGFSTLTMESDKFICIREKVGeQAQVVIIDMN 56
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTK-KGQVQIVDVE 37
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
296-330 |
1.92e-04 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
:
Pssm-ID: 460192 Cd Length: 37 Bit Score: 40.09 E-value: 1.92e-04
10 20 30
....*....|....*....|....*....|....*..
gi 1249618521 296 NRISGETIFVTAPHEATAGIIGVN--RKGQVLSVCVE 330
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINgtKKGQVQIVDVE 37
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
148-187 |
1.70e-03 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
:
Pssm-ID: 460192 Cd Length: 37 Bit Score: 37.40 E-value: 1.70e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1249618521 148 LAGCQIINYRTDAKQKWLLLTGISaqqNRVVGAMQLYSVD 187
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAIN---GTKKGQVQIVDVE 37
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1274-1416 |
4.00e-40 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 145.49 E-value: 4.00e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1274 LHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAE 1353
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1249618521 1354 QAHLWAELVFLYDKYEEYDNAIITMMNHPTDAwkeGQFKDIITKVANVELYYKAIQFYLEFKP 1416
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIEHLGNY---EKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
979-1118 |
1.57e-34 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 129.32 E-value: 1.57e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 979 LSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSvfsEHRNLQNLLILTAIKADRTRVMEYI-NRLDNYDAPDIAN 1057
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNS---ENPALQTKLIELYAKYDPQKEIERLdNKSNHYDIEKVGK 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1249618521 1058 IAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQK 1118
Cdd:smart00299 78 LCEKAKLYEEAVELYKKDGNFKDAIVTLIEHLGNYEKAIEYFVKQNNPELWAEVLKALLDK 138
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1128-1265 |
5.04e-33 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 125.08 E-value: 5.04e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1128 YIKADDPSSYMEVVQAANASGNWEELVKYLQMARKKARE-SYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCY 1206
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSEnPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1207 DEKMYDAAKLLYNNVSNFGRLASTLV-HLGEYQAAVDGARKANSTRTWKEVCFACVDGKE 1265
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIeHLGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
686-824 |
1.48e-32 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 123.92 E-value: 1.48e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 686 ASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNF-SQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLK 764
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLnSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1249618521 765 EAKLTDQLPLIIVCDrFDFVHDLVLYLYR-NNLQKYIEIYVQKVNPSRLPVVIGGLLDVDC 824
Cdd:smart00299 81 KAKLYEEAVELYKKD-GNFKDAIVTLIEHlGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
833-968 |
6.20e-32 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 122.00 E-value: 6.20e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 833 ILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNP--ERFLRENPYYDSRVVGKYCE 910
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKeiERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 911 KRDPH-LACVAYERGQCDLELINVCNENS-LFKSLSRYLVRRKDPELWGSVLLESNPYRR 968
Cdd:smart00299 81 KAKLYeEAVELYKKDGNFKDAIVTLIEHLgNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| Clathrin_H_link |
pfam13838 |
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ... |
356-421 |
6.79e-32 |
|
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.
Pssm-ID: 463995 Cd Length: 66 Bit Score: 119.24 E-value: 6.79e-32
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1249618521 356 NLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGIL 421
Cdd:pfam13838 1 GLPGADDLYFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYFGTL 66
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
979-1119 |
1.66e-31 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 120.82 E-value: 1.66e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 979 LSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSvfSEHRNLQNLLILTAIKADR-TRVMEYINRLDNYDAPDIAN 1057
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDS--RENPALQTALIELYAKYDDpEELEEFLKKNNNYDLEKVAK 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 1058 IAISNELFEEAFAIFRKFDVNTSAVqVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKG 1119
Cdd:pfam00637 79 LCEKADLYEEAVILYKKIGNWKEAI-SLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNG 139
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1128-1267 |
3.93e-31 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 119.67 E-value: 3.93e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1128 YIKADDPSSYMEVVQAANASGNWEELVKYLQMARKKARE--SYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRC 1205
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDSRenPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLC 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 1206 YDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFR 1267
Cdd:pfam00637 81 EKADLYEEAVILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1427-1564 |
8.86e-31 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 118.90 E-value: 8.86e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1427 SPRLDHTRAVNYFSKVKQLPLVKPYLRSVQN---HNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHE 1503
Cdd:pfam00637 5 TDPIDVSRVVKLFEKAGLLEELISYLESALKedsRENPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLCEKAD 84
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1249618521 1504 LIEFRRiaaYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRE 1564
Cdd:pfam00637 85 LYEEAV---ILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
541-674 |
1.19e-29 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 115.45 E-value: 1.19e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 541 EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNrPSEGPLQTRLLEMNLMHAPQVADAILGNqMFTHYDRAHIAQLCEKA 620
Cdd:smart00299 5 SDPIDVSEVVELFEKRNLLEELIPYLESALKLN-SENPALQTKLIELYAKYDPQKEIERLDN-KSNHYDIEKVGKLCEKA 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1249618521 621 GLLQRALEHFTDLYDIKRAVVHT--HLLNPEWLVNYFGS-LSVEDSLECLRAMLSAN 674
Cdd:smart00299 83 KLYEEAVELYKKDGNFKDAIVTLieHLGNYEKAIEYFVKqNNPELWAEVLKALLDKP 139
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1274-1416 |
6.28e-27 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 107.73 E-value: 6.28e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1274 LHIVVHADELEELINYYQDRGYFEELITMLEAALGL-ERAHMGMFTELAILYSKF-KPQKMREHLELFWSrVNIPKVLRA 1351
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEdSRENPALQTALIELYAKYdDPEELEEFLKKNNN-YDLEKVAKL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1249618521 1352 AEQAHLWAELVFLYDKYEEYDNAIitMMNHPTDAWKEGQfkDIITKVANVELYYKAIQFYLEFKP 1416
Cdd:pfam00637 80 CEKADLYEEAVILYKKIGNWKEAI--SLLKKLGDYKDAI--EYAVKSSNPELWEELLEALLDNGR 140
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
843-970 |
7.47e-27 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 107.73 E-value: 7.47e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 843 DELVAEVEKRNRLKLLLPWLEARIHEG-CEEPATHNALAKIYIDSN--NNPERFLRENPYYDSRVVGKYCEKRDPH-LAC 918
Cdd:pfam00637 11 SRVVKLFEKAGLLEELISYLESALKEDsRENPALQTALIELYAKYDdpEELEEFLKKNNNYDLEKVAKLCEKADLYeEAV 90
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 919 VAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPL 970
Cdd:pfam00637 91 ILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
688-826 |
1.42e-26 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 106.96 E-value: 1.42e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 688 KYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFS--QDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKE 765
Cdd:pfam00637 3 ESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDsrENPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLCEK 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 766 AKLTDQLPLIIVCdrFDFVHDLV-LYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSE 826
Cdd:pfam00637 83 ADLYEEAVILYKK--IGNWKEAIsLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
541-678 |
7.25e-24 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 98.87 E-value: 7.25e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 541 EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAP-QVADAILgnQMFTHYDRAHIAQLCEK 619
Cdd:pfam00637 5 TDPIDVSRVVKLFEKAGLLEELISYLESALKEDSRENPALQTALIELYAKYDDpEELEEFL--KKNNNYDLEKVAKLCEK 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 620 AGLLQRALEHFTDLYDIKRAV-VHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQN 678
Cdd:pfam00637 83 ADLYEEAVILYKKIGNWKEAIsLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1427-1578 |
5.23e-22 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 93.49 E-value: 5.23e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1427 SPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNnkSVNESLNNLFITEEDYQALRTSIDAYDNFdnislaqrlekHELIE 1506
Cdd:smart00299 5 SDPIDVSEVVELFEKRNLLEELIPYLESALKLN--SENPALQTKLIELYAKYDPQKEIERLDNK-----------SNHYD 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 1507 FRRIAAYLFKGNNrWKQSVELCKKDSLYKDAMQYASESKdtELAEELLQWFLQEEKRECFGACLFTCYDLLR 1578
Cdd:smart00299 72 IEKVGKLCEKAKL-YEEAVELYKKDGNFKDAIVTLIEHL--GNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| Clathrin-link |
pfam09268 |
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of ... |
331-354 |
4.27e-10 |
|
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of alpha-alpha superhelix. They are predominantly found in clathrin, where they act as a heavy-chain linker domain.
Pssm-ID: 462732 Cd Length: 24 Bit Score: 55.91 E-value: 4.27e-10
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
198-234 |
2.95e-07 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 48.18 E-value: 2.95e-07
10 20 30
....*....|....*....|....*....|....*..
gi 1249618521 198 AASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVG 234
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTKKGQVQIVDVE 37
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1055-1219 |
3.31e-07 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 53.58 E-value: 3.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1055 IANIAISNELFEEAFAIFRKF----DVNTSAVQVLI---EHIGNLDRAYEFAERC-----NEPAVWSQLAKAQLQKGMVK 1122
Cdd:COG2956 82 LAQDYLKAGLLDRAEELLEKLleldPDDAEALRLLAeiyEQEGDWEKAIEVLERLlklgpENAHAYCELAELYLEQGDYD 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1123 EAIDSYIKA-----DDPSSYMEVVQAANASGNWEELVKYLQMARKKARESY-VETELIFALAKTNRLAELEEFI-----N 1191
Cdd:COG2956 162 EAIEALEKAlkldpDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLpALPRLAELYEKLGDPEEALELLrkaleL 241
|
170 180
....*....|....*....|....*...
gi 1249618521 1192 GPNNAHIQQVGDRCYDEKMYDAAKLLYN 1219
Cdd:COG2956 242 DPSDDLLLALADLLERKEGLEAALALLE 269
|
|
| Coatomer_WDAD_beta-like |
cd22947 |
Coatomer WD Associated Region from Coatomer Subunit Beta and Beta'; Coatomer subunit beta', ... |
1061-1185 |
2.01e-06 |
|
Coatomer WD Associated Region from Coatomer Subunit Beta and Beta'; Coatomer subunit beta', also called beta'-coat protein; beta'-COP; p102, is a component of the coatomer, which is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complexes are hetero-oligomers composed of at least an alpha, beta, beta', gamma, delta, epsilon and zeta subunit. It is a heptameric complex that can polymerize into a cage to deform the membrane into a bud. This model corresponds to the WD-associated (WDAD) region found in coatomer subunits beta and beta' and is composed of a beta-propeller and an alpha-solenoid. The WD40 domain is found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. It typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40. Between the GH and WD lies a conserved core. It forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet. Each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade. The last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure. The residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands allowing them to bind either stably or reversibly.
Pssm-ID: 438572 Cd Length: 475 Bit Score: 52.47 E-value: 2.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1061 SNELFEEAFAIFR----KFDVntsAVQvliehIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSS 1136
Cdd:cd22947 324 SQGLKELALEVSTdpdhKFEL---ALQ-----LGDLDLALEIARESESESKWKQLGDLALSKGDFDLAEECLKKAGDLSG 395
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1249618521 1137 YMEVvqaANASGNWEELVKYLQMARKK-----ARESYVET----ELIFALAKTNRLAE 1185
Cdd:cd22947 396 LLLL---YSSTGDKEGLEELAELAEAAgknniAFLAYFLLgdldKCVDLLIKTGRLPE 450
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
256-288 |
4.89e-05 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 42.02 E-value: 4.89e-05
10 20 30
....*....|....*....|....*....|...
gi 1249618521 256 AQNDFPVAMQISEKHDVVFLITKYGYIHLYDLE 288
Cdd:pfam01394 5 AIIIFPTATMESWLFIIAINGTKKGQVQIVDVE 37
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
19-56 |
4.94e-05 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 42.02 E-value: 4.94e-05
10 20 30
....*....|....*....|....*....|....*...
gi 1249618521 19 GINPANIGFSTLTMESDKFICIREKVGeQAQVVIIDMN 56
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTK-KGQVQIVDVE 37
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
296-330 |
1.92e-04 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 40.09 E-value: 1.92e-04
10 20 30
....*....|....*....|....*....|....*..
gi 1249618521 296 NRISGETIFVTAPHEATAGIIGVN--RKGQVLSVCVE 330
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINgtKKGQVQIVDVE 37
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
1054-1164 |
7.80e-04 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 41.33 E-value: 7.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1054 DIANIAISNELFEEAFAIFRKF----DVNTSAVQVLIE---HIGNLDRAYEFAERC-----NEPAVWSQLAKAQLQKGMV 1121
Cdd:COG4783 9 ALAQALLLAGDYDEAEALLEKAleldPDNPEAFALLGEillQLGDLDEAIVLLHEAleldpDEPEARLNLGLALLKAGDY 88
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1249618521 1122 KEAIDSYIKA-----DDPSSYMEVVQAANASGNWEELVKYLQMARKKA 1164
Cdd:COG4783 89 DEALALLEKAlkldpEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
148-187 |
1.70e-03 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 37.40 E-value: 1.70e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1249618521 148 LAGCQIINYRTDAKQKWLLLTGISaqqNRVVGAMQLYSVD 187
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAIN---GTKKGQVQIVDVE 37
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
1054-1186 |
8.79e-03 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 40.75 E-value: 8.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1054 DIANIAISNELFEEAFAIFRKF-DVNTSAVQVLI------EHIGNLDRAYEFAERC-----NEPAVWSQLAKAQLQKGMV 1121
Cdd:COG3914 117 NLGNLLLALGRLEEALAALRRAlALNPDFAEAYLnlgealRRLGRLEEAIAALRRAleldpDNAEALNNLGNALQDLGRL 196
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1122 KEAIDSYIKA-----DDPSSYMEVVQAANASGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAEL 1186
Cdd:COG3914 197 EEAIAAYRRAleldpDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDPAEL 266
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1274-1416 |
4.00e-40 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 145.49 E-value: 4.00e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1274 LHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAE 1353
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1249618521 1354 QAHLWAELVFLYDKYEEYDNAIITMMNHPTDAwkeGQFKDIITKVANVELYYKAIQFYLEFKP 1416
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIEHLGNY---EKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
979-1118 |
1.57e-34 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 129.32 E-value: 1.57e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 979 LSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSvfsEHRNLQNLLILTAIKADRTRVMEYI-NRLDNYDAPDIAN 1057
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNS---ENPALQTKLIELYAKYDPQKEIERLdNKSNHYDIEKVGK 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1249618521 1058 IAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQK 1118
Cdd:smart00299 78 LCEKAKLYEEAVELYKKDGNFKDAIVTLIEHLGNYEKAIEYFVKQNNPELWAEVLKALLDK 138
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1128-1265 |
5.04e-33 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 125.08 E-value: 5.04e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1128 YIKADDPSSYMEVVQAANASGNWEELVKYLQMARKKARE-SYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCY 1206
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSEnPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1207 DEKMYDAAKLLYNNVSNFGRLASTLV-HLGEYQAAVDGARKANSTRTWKEVCFACVDGKE 1265
Cdd:smart00299 81 KAKLYEEAVELYKKDGNFKDAIVTLIeHLGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
686-824 |
1.48e-32 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 123.92 E-value: 1.48e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 686 ASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNF-SQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLK 764
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLnSENPALQTKLIELYAKYDPQKEIERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1249618521 765 EAKLTDQLPLIIVCDrFDFVHDLVLYLYR-NNLQKYIEIYVQKVNPSRLPVVIGGLLDVDC 824
Cdd:smart00299 81 KAKLYEEAVELYKKD-GNFKDAIVTLIEHlGNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
833-968 |
6.20e-32 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 122.00 E-value: 6.20e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 833 ILVVRGQFSTDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNP--ERFLRENPYYDSRVVGKYCE 910
Cdd:smart00299 1 LLEVSDPIDVSEVVELFEKRNLLEELIPYLESALKLNSENPALQTKLIELYAKYDPQKeiERLDNKSNHYDIEKVGKLCE 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 911 KRDPH-LACVAYERGQCDLELINVCNENS-LFKSLSRYLVRRKDPELWGSVLLESNPYRR 968
Cdd:smart00299 81 KAKLYeEAVELYKKDGNFKDAIVTLIEHLgNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| Clathrin_H_link |
pfam13838 |
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins ... |
356-421 |
6.79e-32 |
|
Clathrin-H-link; This short domain is found on clathrins, and often appears on proteins directly downstream from the Clathrin-link domain pfam09268.
Pssm-ID: 463995 Cd Length: 66 Bit Score: 119.24 E-value: 6.79e-32
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1249618521 356 NLAGAEELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGIL 421
Cdd:pfam13838 1 GLPGADDLYFQQFNQLLNQGDYAEAAKVAANSPRGALRTPETIQRFKQLPAQPGQLSPILQYFGTL 66
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
979-1119 |
1.66e-31 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 120.82 E-value: 1.66e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 979 LSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSvfSEHRNLQNLLILTAIKADR-TRVMEYINRLDNYDAPDIAN 1057
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDS--RENPALQTALIELYAKYDDpEELEEFLKKNNNYDLEKVAK 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 1058 IAISNELFEEAFAIFRKFDVNTSAVqVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKG 1119
Cdd:pfam00637 79 LCEKADLYEEAVILYKKIGNWKEAI-SLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNG 139
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1128-1267 |
3.93e-31 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 119.67 E-value: 3.93e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1128 YIKADDPSSYMEVVQAANASGNWEELVKYLQMARKKARE--SYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRC 1205
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDSRenPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLC 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 1206 YDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFACVDGKEFR 1267
Cdd:pfam00637 81 EKADLYEEAVILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1427-1564 |
8.86e-31 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 118.90 E-value: 8.86e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1427 SPRLDHTRAVNYFSKVKQLPLVKPYLRSVQN---HNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLEKHE 1503
Cdd:pfam00637 5 TDPIDVSRVVKLFEKAGLLEELISYLESALKedsRENPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLCEKAD 84
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1249618521 1504 LIEFRRiaaYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRE 1564
Cdd:pfam00637 85 LYEEAV---ILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
541-674 |
1.19e-29 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 115.45 E-value: 1.19e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 541 EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNrPSEGPLQTRLLEMNLMHAPQVADAILGNqMFTHYDRAHIAQLCEKA 620
Cdd:smart00299 5 SDPIDVSEVVELFEKRNLLEELIPYLESALKLN-SENPALQTKLIELYAKYDPQKEIERLDN-KSNHYDIEKVGKLCEKA 82
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 1249618521 621 GLLQRALEHFTDLYDIKRAVVHT--HLLNPEWLVNYFGS-LSVEDSLECLRAMLSAN 674
Cdd:smart00299 83 KLYEEAVELYKKDGNFKDAIVTLieHLGNYEKAIEYFVKqNNPELWAEVLKALLDKP 139
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
1274-1416 |
6.28e-27 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 107.73 E-value: 6.28e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1274 LHIVVHADELEELINYYQDRGYFEELITMLEAALGL-ERAHMGMFTELAILYSKF-KPQKMREHLELFWSrVNIPKVLRA 1351
Cdd:pfam00637 1 LIESTDPIDVSRVVKLFEKAGLLEELISYLESALKEdSRENPALQTALIELYAKYdDPEELEEFLKKNNN-YDLEKVAKL 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1249618521 1352 AEQAHLWAELVFLYDKYEEYDNAIitMMNHPTDAWKEGQfkDIITKVANVELYYKAIQFYLEFKP 1416
Cdd:pfam00637 80 CEKADLYEEAVILYKKIGNWKEAI--SLLKKLGDYKDAI--EYAVKSSNPELWEELLEALLDNGR 140
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
843-970 |
7.47e-27 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 107.73 E-value: 7.47e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 843 DELVAEVEKRNRLKLLLPWLEARIHEG-CEEPATHNALAKIYIDSN--NNPERFLRENPYYDSRVVGKYCEKRDPH-LAC 918
Cdd:pfam00637 11 SRVVKLFEKAGLLEELISYLESALKEDsRENPALQTALIELYAKYDdpEELEEFLKKNNNYDLEKVAKLCEKADLYeEAV 90
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 919 VAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVLLESNPYRRPL 970
Cdd:pfam00637 91 ILYKKIGNWKEAISLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
688-826 |
1.42e-26 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 106.96 E-value: 1.42e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 688 KYHEQLSTQSLIELFESFKSFEGLFYFLGSIVNFS--QDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKE 765
Cdd:pfam00637 3 ESTDPIDVSRVVKLFEKAGLLEELISYLESALKEDsrENPALQTALIELYAKYDDPEELEEFLKKNNNYDLEKVAKLCEK 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 766 AKLTDQLPLIIVCdrFDFVHDLV-LYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSE 826
Cdd:pfam00637 83 ADLYEEAVILYKK--IGNWKEAIsLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| Clathrin |
pfam00637 |
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are ... |
541-678 |
7.25e-24 |
|
Region in Clathrin and VPS; Each region is about 140 amino acids long. The regions are composed of multiple alpha helical repeats. They occur in the arm region of the Clathrin heavy chain.
Pssm-ID: 459884 [Multi-domain] Cd Length: 142 Bit Score: 98.87 E-value: 7.25e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 541 EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAP-QVADAILgnQMFTHYDRAHIAQLCEK 619
Cdd:pfam00637 5 TDPIDVSRVVKLFEKAGLLEELISYLESALKEDSRENPALQTALIELYAKYDDpEELEEFL--KKNNNYDLEKVAKLCEK 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 620 AGLLQRALEHFTDLYDIKRAV-VHTHLLNPEWLVNYFGSLSVEDSLECLRAMLSANIRQN 678
Cdd:pfam00637 83 ADLYEEAVILYKKIGNWKEAIsLLKKLGDYKDAIEYAVKSSNPELWEELLEALLDNGRFE 142
|
|
| CLH |
smart00299 |
Clathrin heavy chain repeat homology; |
1427-1578 |
5.23e-22 |
|
Clathrin heavy chain repeat homology;
Pssm-ID: 128594 [Multi-domain] Cd Length: 140 Bit Score: 93.49 E-value: 5.23e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1427 SPRLDHTRAVNYFSKVKQLPLVKPYLRSVQNHNnkSVNESLNNLFITEEDYQALRTSIDAYDNFdnislaqrlekHELIE 1506
Cdd:smart00299 5 SDPIDVSEVVELFEKRNLLEELIPYLESALKLN--SENPALQTKLIELYAKYDPQKEIERLDNK-----------SNHYD 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1249618521 1507 FRRIAAYLFKGNNrWKQSVELCKKDSLYKDAMQYASESKdtELAEELLQWFLQEEKRECFGACLFTCYDLLR 1578
Cdd:smart00299 72 IEKVGKLCEKAKL-YEEAVELYKKDGNFKDAIVTLIEHL--GNYEKAIEYFVKQNNPELWAEVLKALLDKPR 140
|
|
| Clathrin-link |
pfam09268 |
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of ... |
331-354 |
4.27e-10 |
|
Clathrin, heavy-chain linker; Members of this family adopt a structure consisting of alpha-alpha superhelix. They are predominantly found in clathrin, where they act as a heavy-chain linker domain.
Pssm-ID: 462732 Cd Length: 24 Bit Score: 55.91 E-value: 4.27e-10
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
198-234 |
2.95e-07 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 48.18 E-value: 2.95e-07
10 20 30
....*....|....*....|....*....|....*..
gi 1249618521 198 AASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVG 234
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTKKGQVQIVDVE 37
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1055-1219 |
3.31e-07 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 53.58 E-value: 3.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1055 IANIAISNELFEEAFAIFRKF----DVNTSAVQVLI---EHIGNLDRAYEFAERC-----NEPAVWSQLAKAQLQKGMVK 1122
Cdd:COG2956 82 LAQDYLKAGLLDRAEELLEKLleldPDDAEALRLLAeiyEQEGDWEKAIEVLERLlklgpENAHAYCELAELYLEQGDYD 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1123 EAIDSYIKA-----DDPSSYMEVVQAANASGNWEELVKYLQMARKKARESY-VETELIFALAKTNRLAELEEFI-----N 1191
Cdd:COG2956 162 EAIEALEKAlkldpDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLpALPRLAELYEKLGDPEEALELLrkaleL 241
|
170 180
....*....|....*....|....*...
gi 1249618521 1192 GPNNAHIQQVGDRCYDEKMYDAAKLLYN 1219
Cdd:COG2956 242 DPSDDLLLALADLLERKEGLEAALALLE 269
|
|
| Coatomer_WDAD_beta-like |
cd22947 |
Coatomer WD Associated Region from Coatomer Subunit Beta and Beta'; Coatomer subunit beta', ... |
1061-1185 |
2.01e-06 |
|
Coatomer WD Associated Region from Coatomer Subunit Beta and Beta'; Coatomer subunit beta', also called beta'-coat protein; beta'-COP; p102, is a component of the coatomer, which is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complexes are hetero-oligomers composed of at least an alpha, beta, beta', gamma, delta, epsilon and zeta subunit. It is a heptameric complex that can polymerize into a cage to deform the membrane into a bud. This model corresponds to the WD-associated (WDAD) region found in coatomer subunits beta and beta' and is composed of a beta-propeller and an alpha-solenoid. The WD40 domain is found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. It typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40. Between the GH and WD lies a conserved core. It forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet. Each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade. The last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure. The residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands allowing them to bind either stably or reversibly.
Pssm-ID: 438572 Cd Length: 475 Bit Score: 52.47 E-value: 2.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1061 SNELFEEAFAIFR----KFDVntsAVQvliehIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSS 1136
Cdd:cd22947 324 SQGLKELALEVSTdpdhKFEL---ALQ-----LGDLDLALEIARESESESKWKQLGDLALSKGDFDLAEECLKKAGDLSG 395
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1249618521 1137 YMEVvqaANASGNWEELVKYLQMARKK-----ARESYVET----ELIFALAKTNRLAE 1185
Cdd:cd22947 396 LLLL---YSSTGDKEGLEELAELAEAAgknniAFLAYFLLgdldKCVDLLIKTGRLPE 450
|
|
| Coatomer_WDAD |
pfam04053 |
Coatomer WD associated region; This region is composed of WD40 repeats. |
1074-1163 |
3.17e-06 |
|
Coatomer WD associated region; This region is composed of WD40 repeats.
Pssm-ID: 427679 Cd Length: 439 Bit Score: 51.47 E-value: 3.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1074 KFDVntsAVQvliehIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSS----YMevvqaanASGN 1149
Cdd:pfam04053 320 RFDL---ALE-----LGNLDVALEIAKELDDPAKWKRLGDAALSQGNIKLAEEAYQKAKDFDKllllYL-------STGN 384
|
90
....*....|....
gi 1249618521 1150 WEELVKYLQMARKK 1163
Cdd:pfam04053 385 MEKLKKLAKIAEKR 398
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1056-1247 |
1.18e-05 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 48.96 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1056 ANIAISNELFEEAFAIFRK-FDVNTSAVQVLI------EHIGNLDRAYEFAERC-----NEPAVWSQLAKAQLQKGMVKE 1123
Cdd:COG2956 15 GLNYLLNGQPDKAIDLLEEaLELDPETVEAHLalgnlyRRRGEYDRAIRIHQKLlerdpDRAEALLELAQDYLKAGLLDR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1124 AIDSYIKA-----DDPSSYMEVVQAANASGNWEELVKYLQMARKKARES-YVETELIFALAKTNRLAE----LEEFING- 1192
Cdd:COG2956 95 AEELLEKLleldpDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENaHAYCELAELYLEQGDYDEaieaLEKALKLd 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1249618521 1193 PNNAHIQ-QVGDRCYDEKMYDAAKLLY--------NNVSNFGRLASTLVHLGEYQAAVDGARKA 1247
Cdd:COG2956 175 PDCARALlLLAELYLEQGDYEEAIAALeraleqdpDYLPALPRLAELYEKLGDPEEALELLRKA 238
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
256-288 |
4.89e-05 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 42.02 E-value: 4.89e-05
10 20 30
....*....|....*....|....*....|...
gi 1249618521 256 AQNDFPVAMQISEKHDVVFLITKYGYIHLYDLE 288
Cdd:pfam01394 5 AIIIFPTATMESWLFIIAINGTKKGQVQIVDVE 37
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
19-56 |
4.94e-05 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 42.02 E-value: 4.94e-05
10 20 30
....*....|....*....|....*....|....*...
gi 1249618521 19 GINPANIGFSTLTMESDKFICIREKVGeQAQVVIIDMN 56
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINGTK-KGQVQIVDVE 37
|
|
| LapB |
COG2956 |
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ... |
1108-1375 |
1.01e-04 |
|
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442196 [Multi-domain] Cd Length: 275 Bit Score: 46.26 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1108 WSQLAKAQLQKGMVKEAIDSYIKA-----DDPSSYMEVVQAANASGNWEELVKYLQMARKKARESY-VETELIFALAKTN 1181
Cdd:COG2956 11 WYFKGLNYLLNGQPDKAIDLLEEAleldpETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAeALLELAQDYLKAG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1182 RLAELEEFIN-----GPNNAH-IQQVGDRCYDEKMYDAAKLLYNNVSNFG--------RLASTLVHLGEYQAAVDGARKA 1247
Cdd:COG2956 91 LLDRAEELLEkllelDPDDAEaLRLLAEIYEQEGDWEKAIEVLERLLKLGpenahaycELAELYLEQGDYDEAIEALEKA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1248 NSTRtwkevcfacvdgKEFRLAQMcglhivvhadeleELINYYQDRGYFEELITMLEAALGLERAHMGMFTELAILYSKF 1327
Cdd:COG2956 171 LKLD------------PDCARALL-------------LLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL 225
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1249618521 1328 -KPQKMREHLElfwsrvnipKVLRAAEQAHLWAELVFLYDKYEEYDNAI 1375
Cdd:COG2956 226 gDPEEALELLR---------KALELDPSDDLLLALADLLERKEGLEAAL 265
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
296-330 |
1.92e-04 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 40.09 E-value: 1.92e-04
10 20 30
....*....|....*....|....*....|....*..
gi 1249618521 296 NRISGETIFVTAPHEATAGIIGVN--RKGQVLSVCVE 330
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAINgtKKGQVQIVDVE 37
|
|
| BepA |
COG4783 |
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ... |
1054-1164 |
7.80e-04 |
|
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443813 [Multi-domain] Cd Length: 139 Bit Score: 41.33 E-value: 7.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1054 DIANIAISNELFEEAFAIFRKF----DVNTSAVQVLIE---HIGNLDRAYEFAERC-----NEPAVWSQLAKAQLQKGMV 1121
Cdd:COG4783 9 ALAQALLLAGDYDEAEALLEKAleldPDNPEAFALLGEillQLGDLDEAIVLLHEAleldpDEPEARLNLGLALLKAGDY 88
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1249618521 1122 KEAIDSYIKA-----DDPSSYMEVVQAANASGNWEELVKYLQMARKKA 1164
Cdd:COG4783 89 DEALALLEKAlkldpEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
|
|
| Clathrin_propel |
pfam01394 |
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that ... |
148-187 |
1.70e-03 |
|
Clathrin propeller repeat; Clathrin is the scaffold protein of the basket-like coat that surrounds coated vesicles. The soluble assembly unit, a triskelion, contains three heavy chains and three light chains in an extended three-legged structure. Each leg contains one heavy and one light chain. The N-terminus of the heavy chain is known as the globular domain, and is composed of seven repeats which form a beta propeller.
Pssm-ID: 460192 Cd Length: 37 Bit Score: 37.40 E-value: 1.70e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 1249618521 148 LAGCQIINYRTDAKQKWLLLTGISaqqNRVVGAMQLYSVD 187
Cdd:pfam01394 1 NAISAIIIFPTATMESWLFIIAIN---GTKKGQVQIVDVE 37
|
|
| COG4700 |
COG4700 |
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown]; |
1088-1189 |
4.42e-03 |
|
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
Pssm-ID: 443735 [Multi-domain] Cd Length: 249 Bit Score: 40.64 E-value: 4.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1088 HIGNLDRAYEFAercNEPAVWSQLAKAQLQKGMVKEAIDSYIKA------DDPSSYMEVVQAANASGNWEELVKYLQMAR 1161
Cdd:COG4700 75 ELRELEKALEFA---DTVQNRVRLADALLELGRYDEAIELYEEAltgifaDDPHILLGLAQALFELGRYAEALETLEKLI 151
|
90 100
....*....|....*....|....*....
gi 1249618521 1162 KKARES-YVETELIFALAktnrLAELEEF 1189
Cdd:COG4700 152 AKNPDFkSSDAHLLYARA----LEALGDL 176
|
|
| Spy |
COG3914 |
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ... |
1054-1186 |
8.79e-03 |
|
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443119 [Multi-domain] Cd Length: 658 Bit Score: 40.75 E-value: 8.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1054 DIANIAISNELFEEAFAIFRKF-DVNTSAVQVLI------EHIGNLDRAYEFAERC-----NEPAVWSQLAKAQLQKGMV 1121
Cdd:COG3914 117 NLGNLLLALGRLEEALAALRRAlALNPDFAEAYLnlgealRRLGRLEEAIAALRRAleldpDNAEALNNLGNALQDLGRL 196
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1249618521 1122 KEAIDSYIKA-----DDPSSYMEVVQAANASGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAEL 1186
Cdd:COG3914 197 EEAIAAYRRAleldpDNADAHSNLLFALRQACDWEVYDRFEELLAALARGPSELSPFALLYLPDDDPAEL 266
|
|
| |
