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Conserved domains on  [gi|1248026887|ref|NP_001343260|]
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pre-mRNA-splicing factor SPF27 isoform 3 [Mus musculus]

Protein Classification

pre-mRNA-splicing factor SPF27 family protein( domain architecture ID 10529685)

pre-mRNA-splicing factor SPF27 family protein similar to human SPF27, also called breast carcinoma-amplified sequence 2 or BCAS2, that is required for pre-mRNA splicing as a component of the activated spliceosome

Gene Ontology:  GO:0006397

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BCAS2 pfam05700
Breast carcinoma amplified sequence 2 (BCAS2); This family consists of several eukaryotic ...
 1-148 1.16e-74

Breast carcinoma amplified sequence 2 (BCAS2); This family consists of several eukaryotic sequences of unknown function. The mammalian members of this family are annotated as breast carcinoma amplified sequence 2 (BCAS2) proteins. BCAS2 is a putative spliceosome associated protein.


:

Pssm-ID: 428593 [Multi-domain]  Cd Length: 204  Bit Score: 221.69  E-value: 1.16e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248026887   1 MRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHM 80
Cdd:pfam05700  56 LAAELERVEAGQPLTALDLSRYELPAPPSGKRNDLEAWKEALDNAYAQLEHQRIRIENLELLQKYGANAWRLHNYQLEAI 135

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1248026887  81 IEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQH 148
Cdd:pfam05700 136 LRRLEKELAETKEAIEEVNRQRKNAQTAAGGELRSLEEKWKELVSKNLEIEAACEALEAEILELKRQA 203
 
Name Accession Description Interval E-value
BCAS2 pfam05700
Breast carcinoma amplified sequence 2 (BCAS2); This family consists of several eukaryotic ...
 1-148 1.16e-74

Breast carcinoma amplified sequence 2 (BCAS2); This family consists of several eukaryotic sequences of unknown function. The mammalian members of this family are annotated as breast carcinoma amplified sequence 2 (BCAS2) proteins. BCAS2 is a putative spliceosome associated protein.


Pssm-ID: 428593 [Multi-domain]  Cd Length: 204  Bit Score: 221.69  E-value: 1.16e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248026887   1 MRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHM 80
Cdd:pfam05700  56 LAAELERVEAGQPLTALDLSRYELPAPPSGKRNDLEAWKEALDNAYAQLEHQRIRIENLELLQKYGANAWRLHNYQLEAI 135

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1248026887  81 IEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQH 148
Cdd:pfam05700 136 LRRLEKELAETKEAIEEVNRQRKNAQTAAGGELRSLEEKWKELVSKNLEIEAACEALEAEILELKRQA 203
 
Name Accession Description Interval E-value
BCAS2 pfam05700
Breast carcinoma amplified sequence 2 (BCAS2); This family consists of several eukaryotic ...
 1-148 1.16e-74

Breast carcinoma amplified sequence 2 (BCAS2); This family consists of several eukaryotic sequences of unknown function. The mammalian members of this family are annotated as breast carcinoma amplified sequence 2 (BCAS2) proteins. BCAS2 is a putative spliceosome associated protein.


Pssm-ID: 428593 [Multi-domain]  Cd Length: 204  Bit Score: 221.69  E-value: 1.16e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1248026887   1 MRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHM 80
Cdd:pfam05700  56 LAAELERVEAGQPLTALDLSRYELPAPPSGKRNDLEAWKEALDNAYAQLEHQRIRIENLELLQKYGANAWRLHNYQLEAI 135

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1248026887  81 IEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQH 148
Cdd:pfam05700 136 LRRLEKELAETKEAIEEVNRQRKNAQTAAGGELRSLEEKWKELVSKNLEIEAACEALEAEILELKRQA 203
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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