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Conserved domains on  [gi|1212624008|ref|NP_001340065|]
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XIAP-associated factor 1 isoform 4 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
XAF1_C pfam18608
XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino ...
 191-241 5.95e-25

XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino acids interferon (INF)-inducible pro-apoptotic protein. The XIAP binding region within XAF1, XIAP RING binding site, is located at the C-terminal portion of XAF1. This entry represents the C-terminal region which is functionally identified as XIAP RING-binding domain of XAF1.


:

Pssm-ID: 465820  Cd Length: 51  Bit Score: 92.95  E-value: 5.95e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1212624008 191 TSSPRGDKAAYDILRRCSQCGILLPLPILNQHQEKCRWLASSKGKQVRNFS 241
Cdd:pfam18608   1 SPSALKDEAAYDILRRCSQCGILLPLPTLNQHQEKCLWLASLKGKQMRNKS 51
PLN03086 super family cl29366
PRLI-interacting factor K; Provisional
 2-60 1.82e-05

PRLI-interacting factor K; Provisional


The actual alignment was detected with superfamily member PLN03086:

Pssm-ID: 178635 [Multi-domain]  Cd Length: 567  Bit Score: 45.25  E-value: 1.82e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1212624008   2 CQQSMQKSSLEFHKANECQERPVECKFCKlDM------------QLSKLELHESYCGSRTELCQGCGQFIM 60
Cdd:PLN03086  483 CGVVLEKEQMVQHQASTCPLRLITCRFCG-DMvqaggsamdvrdRLRGMSEHESICGSRTAPCDSCGRSVM 552
 
Name Accession Description Interval E-value
XAF1_C pfam18608
XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino ...
 191-241 5.95e-25

XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino acids interferon (INF)-inducible pro-apoptotic protein. The XIAP binding region within XAF1, XIAP RING binding site, is located at the C-terminal portion of XAF1. This entry represents the C-terminal region which is functionally identified as XIAP RING-binding domain of XAF1.


Pssm-ID: 465820  Cd Length: 51  Bit Score: 92.95  E-value: 5.95e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1212624008 191 TSSPRGDKAAYDILRRCSQCGILLPLPILNQHQEKCRWLASSKGKQVRNFS 241
Cdd:pfam18608   1 SPSALKDEAAYDILRRCSQCGILLPLPTLNQHQEKCLWLASLKGKQMRNKS 51
PLN03086 PLN03086
PRLI-interacting factor K; Provisional
 2-60 1.82e-05

PRLI-interacting factor K; Provisional


Pssm-ID: 178635 [Multi-domain]  Cd Length: 567  Bit Score: 45.25  E-value: 1.82e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1212624008   2 CQQSMQKSSLEFHKANECQERPVECKFCKlDM------------QLSKLELHESYCGSRTELCQGCGQFIM 60
Cdd:PLN03086  483 CGVVLEKEQMVQHQASTCPLRLITCRFCG-DMvqaggsamdvrdRLRGMSEHESICGSRTAPCDSCGRSVM 552
 
Name Accession Description Interval E-value
XAF1_C pfam18608
XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino ...
 191-241 5.95e-25

XIAP-associated factor 1 C-terminal domain; XIAP-associated factor 1 (XAF1) is a 301-amino acids interferon (INF)-inducible pro-apoptotic protein. The XIAP binding region within XAF1, XIAP RING binding site, is located at the C-terminal portion of XAF1. This entry represents the C-terminal region which is functionally identified as XIAP RING-binding domain of XAF1.


Pssm-ID: 465820  Cd Length: 51  Bit Score: 92.95  E-value: 5.95e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1212624008 191 TSSPRGDKAAYDILRRCSQCGILLPLPILNQHQEKCRWLASSKGKQVRNFS 241
Cdd:pfam18608   1 SPSALKDEAAYDILRRCSQCGILLPLPTLNQHQEKCLWLASLKGKQMRNKS 51
PLN03086 PLN03086
PRLI-interacting factor K; Provisional
 2-60 1.82e-05

PRLI-interacting factor K; Provisional


Pssm-ID: 178635 [Multi-domain]  Cd Length: 567  Bit Score: 45.25  E-value: 1.82e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1212624008   2 CQQSMQKSSLEFHKANECQERPVECKFCKlDM------------QLSKLELHESYCGSRTELCQGCGQFIM 60
Cdd:PLN03086  483 CGVVLEKEQMVQHQASTCPLRLITCRFCG-DMvqaggsamdvrdRLRGMSEHESICGSRTAPCDSCGRSVM 552
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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