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Conserved domains on  [gi|1178431710|ref|NP_001337224|]
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guided entry of tail-anchored proteins factor 1 isoform 2 [Homo sapiens]

Protein Classification

guided entry of tail-anchored proteins factor 1( domain architecture ID 10516707)

guided entry of tail-anchored proteins factor 1 (get1) functions in the post-translational delivery of tail-anchored proteins to the endoplasmic reticulum

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CHD5 pfam04420
CHD5-like protein; Members of this family are probably coiled-coil proteins that are similar ...
 7-129 1.74e-41

CHD5-like protein; Members of this family are probably coiled-coil proteins that are similar to the CHD5 (Congenital heart disease 5) protein. In Saccharomyces cerevisiae this protein localizes to the ER and is thought to play a homeostatic role.


:

Pssm-ID: 427938  Cd Length: 158  Bit Score: 135.01  E-value: 1.74e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431710   7 KDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVISVAFYVLQAALMISLI 86
Cdd:pfam04420  35 KLAKEQRKLKAEILKLKEELNATSAQDEFAKWAKLNRKHDKLLEELEKLKKSLSSAKSSFDKLLKKVRWVLTTGPQFFLK 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1178431710  87 WKYYSVPVAVVPSKWI-TPLDRLVAFPTRVAGGVGITCWILVCN 129
Cdd:pfam04420 115 FWYRKTPVFWLPKGWFpYYVEWLLSFPTAPLGSVSLTVWLFACN 158
 
Name Accession Description Interval E-value
CHD5 pfam04420
CHD5-like protein; Members of this family are probably coiled-coil proteins that are similar ...
 7-129 1.74e-41

CHD5-like protein; Members of this family are probably coiled-coil proteins that are similar to the CHD5 (Congenital heart disease 5) protein. In Saccharomyces cerevisiae this protein localizes to the ER and is thought to play a homeostatic role.


Pssm-ID: 427938  Cd Length: 158  Bit Score: 135.01  E-value: 1.74e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431710   7 KDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVISVAFYVLQAALMISLI 86
Cdd:pfam04420  35 KLAKEQRKLKAEILKLKEELNATSAQDEFAKWAKLNRKHDKLLEELEKLKKSLSSAKSSFDKLLKKVRWVLTTGPQFFLK 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1178431710  87 WKYYSVPVAVVPSKWI-TPLDRLVAFPTRVAGGVGITCWILVCN 129
Cdd:pfam04420 115 FWYRKTPVFWLPKGWFpYYVEWLLSFPTAPLGSVSLTVWLFACN 158
 
Name Accession Description Interval E-value
CHD5 pfam04420
CHD5-like protein; Members of this family are probably coiled-coil proteins that are similar ...
 7-129 1.74e-41

CHD5-like protein; Members of this family are probably coiled-coil proteins that are similar to the CHD5 (Congenital heart disease 5) protein. In Saccharomyces cerevisiae this protein localizes to the ER and is thought to play a homeostatic role.


Pssm-ID: 427938  Cd Length: 158  Bit Score: 135.01  E-value: 1.74e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1178431710   7 KDAEQESQMRAEIQDMKQELSTVNMMDEFARYARLERKINKMTDKLKTHVKARTAQLAKIKWVISVAFYVLQAALMISLI 86
Cdd:pfam04420  35 KLAKEQRKLKAEILKLKEELNATSAQDEFAKWAKLNRKHDKLLEELEKLKKSLSSAKSSFDKLLKKVRWVLTTGPQFFLK 114

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1178431710  87 WKYYSVPVAVVPSKWI-TPLDRLVAFPTRVAGGVGITCWILVCN 129
Cdd:pfam04420 115 FWYRKTPVFWLPKGWFpYYVEWLLSFPTAPLGSVSLTVWLFACN 158
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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