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Conserved domains on  [gi|1043523347|ref|NP_001316402|]
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transmembrane protein 243 isoform b [Homo sapiens]

Protein Classification

TMEM243 family protein( domain architecture ID 10566815)

TMEM243 family protein is a DUF2678 domain-containing protein; similar to Homo sapiens transmembrane protein 243, also known as MDR1- and mitochondrial taxol resistance-associated protein (MM-TRAG), a novel intracellular mitochondrial protein associated with the taxol- and doxorubicin-resistant phenotype in human cancer cell lines

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2678 pfam10856
Protein of unknown function (DUF2678); This family of proteins has no known function.
 1-118 8.03e-70

Protein of unknown function (DUF2678); This family of proteins has no known function.


:

Pssm-ID: 463191  Cd Length: 118  Bit Score: 204.65  E-value: 8.03e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1043523347   1 MEDFATRTYGTSGLDNRPLFGETSAKDRIINLVVGSLTSLLILVTLISAFVFPQLPPKPLNIFFAVCISLSSITACILIY 80
Cdd:pfam10856   1 MDDFRTRTYGTSGLDNRPLFGETSARDRIINLAVGGLTSLLVLVTVISSFVFPTLPPKPLNIFFAVCILLICSSVLVLIF 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1043523347  81 WYRQGDLEPKFRKLIYYIIFSIIMLCICANLYFHDVGR 118
Cdd:pfam10856  81 WYRQGDLEPKFRNLIYYMIGSIILLCLCANLYFHDVGR 118
 
Name Accession Description Interval E-value
DUF2678 pfam10856
Protein of unknown function (DUF2678); This family of proteins has no known function.
 1-118 8.03e-70

Protein of unknown function (DUF2678); This family of proteins has no known function.


Pssm-ID: 463191  Cd Length: 118  Bit Score: 204.65  E-value: 8.03e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1043523347   1 MEDFATRTYGTSGLDNRPLFGETSAKDRIINLVVGSLTSLLILVTLISAFVFPQLPPKPLNIFFAVCISLSSITACILIY 80
Cdd:pfam10856   1 MDDFRTRTYGTSGLDNRPLFGETSARDRIINLAVGGLTSLLVLVTVISSFVFPTLPPKPLNIFFAVCILLICSSVLVLIF 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1043523347  81 WYRQGDLEPKFRKLIYYIIFSIIMLCICANLYFHDVGR 118
Cdd:pfam10856  81 WYRQGDLEPKFRNLIYYMIGSIILLCLCANLYFHDVGR 118
 
Name Accession Description Interval E-value
DUF2678 pfam10856
Protein of unknown function (DUF2678); This family of proteins has no known function.
 1-118 8.03e-70

Protein of unknown function (DUF2678); This family of proteins has no known function.


Pssm-ID: 463191  Cd Length: 118  Bit Score: 204.65  E-value: 8.03e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1043523347   1 MEDFATRTYGTSGLDNRPLFGETSAKDRIINLVVGSLTSLLILVTLISAFVFPQLPPKPLNIFFAVCISLSSITACILIY 80
Cdd:pfam10856   1 MDDFRTRTYGTSGLDNRPLFGETSARDRIINLAVGGLTSLLVLVTVISSFVFPTLPPKPLNIFFAVCILLICSSVLVLIF 80

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1043523347  81 WYRQGDLEPKFRKLIYYIIFSIIMLCICANLYFHDVGR 118
Cdd:pfam10856  81 WYRQGDLEPKFRNLIYYMIGSIILLCLCANLYFHDVGR 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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