|
Name |
Accession |
Description |
Interval |
E-value |
| Adk |
COG0563 |
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ... |
17-184 |
2.68e-81 |
|
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440329 [Multi-domain] Cd Length: 212 Bit Score: 240.03 E-value: 2.68e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGF 54
Cdd:COG0563 2 RIILLGPPGAGKGTQakrlaekygiphistgdmlraavkagtelgkkakeymdagelVPDEIVIGLVKERLAQPDCANGF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 55 LLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRS 134
Cdd:COG0563 82 ILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 982742441 135 DDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAA 184
Cdd:COG0563 162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAI 211
|
|
| adk |
PRK00279 |
adenylate kinase; Reviewed |
17-187 |
1.51e-79 |
|
adenylate kinase; Reviewed
Pssm-ID: 234711 [Multi-domain] Cd Length: 215 Bit Score: 235.81 E-value: 1.51e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGF 54
Cdd:PRK00279 2 RLILLGPPGAGKGTQakfiaekygiphistgdmlraavkagtelgkeaksymdagelVPDEIVIGLVKERLAQPDCKNGF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 55 LLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRS 134
Cdd:PRK00279 82 LLDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 982742441 135 DDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 187
Cdd:PRK00279 162 DDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGK 214
|
|
| ADK |
pfam00406 |
Adenylate kinase; |
20-162 |
4.50e-76 |
|
Adenylate kinase;
Pssm-ID: 395329 [Multi-domain] Cd Length: 184 Bit Score: 226.04 E-value: 4.50e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 20 LLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGFLLD 57
Cdd:pfam00406 1 LLGPPGAGKGTQaekivqkyglphlstgdllraeiksgtelgkeakeymdkgelVPDEVVVGLVKERLEQNDCKNGFLLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 58 GFPRTVRQAEMLDDLMEkRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDN 137
Cdd:pfam00406 81 GFPRTVPQAEALEELLE-RGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDN 159
|
170 180
....*....|....*....|....*
gi 982742441 138 EKALKIRLQAYHTQTTPLIEYYRKR 162
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
|
|
| adk |
TIGR01351 |
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ... |
17-186 |
2.68e-70 |
|
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 273569 [Multi-domain] Cd Length: 210 Bit Score: 212.09 E-value: 2.68e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLET-PLCKNG 53
Cdd:TIGR01351 1 RLVLLGPPGSGKGTQakriaekyglphistgdllraeikagtplgkkakeymekgelVPDEIVNQLVKERLTQnDDNENG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 54 FLLDGFPRTVRQAEMLDDLMekrKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRR 133
Cdd:TIGR01351 81 FILDGFPRTLSQAEALDALL---EEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQR 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 982742441 134 SDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFS 186
Cdd:TIGR01351 158 EDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
|
|
| ADK |
cd01428 |
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ... |
17-177 |
4.86e-66 |
|
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.
Pssm-ID: 238713 [Multi-domain] Cd Length: 194 Bit Score: 200.93 E-value: 4.86e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGF 54
Cdd:cd01428 1 RILLLGPPGSGKGTQaerlakkyglphistgdllreeiasgtelgkkakeyidsgklVPDEIVIKLLKERLKKPDCKKGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 55 LLDGFPRTVRQAEMLDDLMEKRKeKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEefnppkepMKDDITGEPLIRRS 134
Cdd:cd01428 81 ILDGFPRTVDQAEALDELLDEGI-KPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRS 151
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 982742441 135 DDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVV 177
Cdd:cd01428 152 DDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Adk |
COG0563 |
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or ... |
17-184 |
2.68e-81 |
|
Adenylate kinase or related kinase [Nucleotide transport and metabolism]; Adenylate kinase or related kinase is part of the Pathway/BioSystem: Pyrimidine biosynthesis
Pssm-ID: 440329 [Multi-domain] Cd Length: 212 Bit Score: 240.03 E-value: 2.68e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGF 54
Cdd:COG0563 2 RIILLGPPGAGKGTQakrlaekygiphistgdmlraavkagtelgkkakeymdagelVPDEIVIGLVKERLAQPDCANGF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 55 LLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRS 134
Cdd:COG0563 82 ILDGFPRTVAQAEALDELLAELGIKLDAVIELDVDDEELVERLSGRRVCPNCGATYHVKFNPPKVEGVCDKCGGELVQRA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 982742441 135 DDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAA 184
Cdd:COG0563 162 DDNEETVRKRLEVYHEQTAPLIDYYRKKGKLVEIDGEGSIEEVTADILAI 211
|
|
| adk |
PRK00279 |
adenylate kinase; Reviewed |
17-187 |
1.51e-79 |
|
adenylate kinase; Reviewed
Pssm-ID: 234711 [Multi-domain] Cd Length: 215 Bit Score: 235.81 E-value: 1.51e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGF 54
Cdd:PRK00279 2 RLILLGPPGAGKGTQakfiaekygiphistgdmlraavkagtelgkeaksymdagelVPDEIVIGLVKERLAQPDCKNGF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 55 LLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRS 134
Cdd:PRK00279 82 LLDGFPRTIPQAEALDEMLKELGIKLDAVIEIDVPDEELVERLSGRRICPACGRTYHVKFNPPKVEGKCDVCGEELIQRA 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 982742441 135 DDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 187
Cdd:PRK00279 162 DDNEETVRKRLEVYHKQTAPLIDYYKKKGKLKKIDGTGSIDEVFADILKALGK 214
|
|
| ADK |
pfam00406 |
Adenylate kinase; |
20-162 |
4.50e-76 |
|
Adenylate kinase;
Pssm-ID: 395329 [Multi-domain] Cd Length: 184 Bit Score: 226.04 E-value: 4.50e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 20 LLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGFLLD 57
Cdd:pfam00406 1 LLGPPGAGKGTQaekivqkyglphlstgdllraeiksgtelgkeakeymdkgelVPDEVVVGLVKERLEQNDCKNGFLLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 58 GFPRTVRQAEMLDDLMEkRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDN 137
Cdd:pfam00406 81 GFPRTVPQAEALEELLE-RGIKLDYVIEFDVPDEVLVERLTGRRIHPNSGRSYHLEFNPPKVPGKDDVTGEPLVQRSDDN 159
|
170 180
....*....|....*....|....*
gi 982742441 138 EKALKIRLQAYHTQTTPLIEYYRKR 162
Cdd:pfam00406 160 EETVKKRLETYHKQTKPLIDYYKKK 184
|
|
| adk |
TIGR01351 |
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ... |
17-186 |
2.68e-70 |
|
adenylate kinase; Adenylate kinase (EC 2.7.4.3) converts ATP + AMP to ADP + ADP, that is, uses ATP as a phosphate donor for AMP. Most members of this family are known or believed to be adenylate kinase. However, some members accept other nucleotide triphosphates as donors, may be unable to use ATP, and may fail to complement adenylate kinase mutants. An example of a nucleoside-triphosphate--adenylate kinase (EC 2.7.4.10) is SP|Q9UIJ7, a GTP:AMP phosphotransferase. This family is designated subfamily rather than equivalog for this reason. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions]
Pssm-ID: 273569 [Multi-domain] Cd Length: 210 Bit Score: 212.09 E-value: 2.68e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLET-PLCKNG 53
Cdd:TIGR01351 1 RLVLLGPPGSGKGTQakriaekyglphistgdllraeikagtplgkkakeymekgelVPDEIVNQLVKERLTQnDDNENG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 54 FLLDGFPRTVRQAEMLDDLMekrKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRR 133
Cdd:TIGR01351 81 FILDGFPRTLSQAEALDALL---EEPIDAVIELDVPDEELVERLSGRRICPSCGRVYHLKFNPPKVPGCDDCTGELLVQR 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 982742441 134 SDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFS 186
Cdd:TIGR01351 158 EDDTEEVVKKRLEVYKEQTEPLIDYYKKRGILVQIDGNGPIDEVWKRILEALK 210
|
|
| ADK |
cd01428 |
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine ... |
17-177 |
4.86e-66 |
|
Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for homeostasis of adenosine phosphates.
Pssm-ID: 238713 [Multi-domain] Cd Length: 194 Bit Score: 200.93 E-value: 4.86e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGF 54
Cdd:cd01428 1 RILLLGPPGSGKGTQaerlakkyglphistgdllreeiasgtelgkkakeyidsgklVPDEIVIKLLKERLKKPDCKKGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 55 LLDGFPRTVRQAEMLDDLMEKRKeKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEefnppkepMKDDITGEPLIRRS 134
Cdd:cd01428 81 ILDGFPRTVDQAEALDELLDEGI-KPDKVIELDVPDEVLIERILGRRICPVSGRVYHL--------GKDDVTGEPLSQRS 151
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 982742441 135 DDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVV 177
Cdd:cd01428 152 DDNEETIKKRLEVYKEQTAPLIDYYKKKGKLVEIDGSGDIDEV 194
|
|
| PLN02674 |
PLN02674 |
adenylate kinase |
17-186 |
5.96e-63 |
|
adenylate kinase
Pssm-ID: 178279 [Multi-domain] Cd Length: 244 Bit Score: 194.72 E-value: 5.96e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGF 54
Cdd:PLN02674 33 RLILIGPPGSGKGTQspiikdeyclchlatgdmlraavaaktplgikakeamdkgelVSDDLVVGIIDEAMKKPSCQKGF 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 55 LLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRS 134
Cdd:PLN02674 113 ILDGFPRTVVQAQKLDEMLAKQGAKIDKVLNFAIDDAILEERITGRWIHPSSGRTYHTKFAPPKVPGVDDVTGEPLIQRK 192
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 982742441 135 DDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFS 186
Cdd:PLN02674 193 DDTAAVLKSRLEAFHKQTEPVIDYYAKKGVVANLHAEKPPKEVTAEVQKALS 244
|
|
| PRK14530 |
PRK14530 |
adenylate kinase; Provisional |
17-189 |
4.09e-40 |
|
adenylate kinase; Provisional
Pssm-ID: 237747 [Multi-domain] Cd Length: 215 Bit Score: 135.69 E-value: 4.09e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ----------------------------------------------VSDEMVVELIEKNLETplc 50
Cdd:PRK14530 5 RILLLGAPGAGKGTQssnlaeefgvehvttgdalrankqmdisdmdteydtpgeymdagelVPDAVVNEIVEEALSD--- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 51 KNGFLLDGFPRTVRQAEMLDDLMEkrkekLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPL 130
Cdd:PRK14530 82 ADGFVLDGYPRNLEQAEYLESITD-----LDVVLYLDVSEEELVDRLTGRRVCPDCGANYHVEFNQPEEEGVCDECGGEL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 982742441 131 IRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKAT 189
Cdd:PRK14530 157 IQRDDDTEETVRERLDVFEENTEPVIEHYRDQGVLVEVDGEQTPDEVWADIQDAIDDAT 215
|
|
| PRK14532 |
PRK14532 |
adenylate kinase; Provisional |
19-188 |
7.81e-36 |
|
adenylate kinase; Provisional
Pssm-ID: 184729 [Multi-domain] Cd Length: 188 Bit Score: 123.78 E-value: 7.81e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 19 VLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGFLL 56
Cdd:PRK14532 4 ILFGPPAAGKGTQakrlveergmvqlstgdmlraaiasgselgqrvkgimdrgelVSDEIVIALIEERLPEAEAAGGAIF 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 57 DGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRlihpksgrsYHEEfnppkepmkdditgepliRRSDD 136
Cdd:PRK14532 84 DGFPRTVAQAEALDKMLASRGQKIDVVIRLKVDDEALIERIVKR---------FEEQ------------------GRPDD 136
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 982742441 137 NEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKA 188
Cdd:PRK14532 137 NPEVFVTRLDAYNAQTAPLLPYYAGQGKLTEVDGMGSIEAVAASIDAALEGV 188
|
|
| adk |
PRK02496 |
adenylate kinase; Provisional |
16-184 |
2.03e-32 |
|
adenylate kinase; Provisional
Pssm-ID: 179433 [Multi-domain] Cd Length: 184 Bit Score: 114.85 E-value: 2.03e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 16 IRAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNG 53
Cdd:PRK02496 2 TRLIFLGPPGAGKGTQavvlaehlhiphistgdilrqaikeqtplgikaqgymdkgelVPDQLVLDLVQERLQQPDAANG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 54 FLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRlihpksgrsyheefnppkepmkdditgepliRR 133
Cdd:PRK02496 82 WILDGFPRKVTQAAFLDELLQEIGQSGERVVNLDVPDDVVVERLLAR-------------------------------GR 130
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 982742441 134 SDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAA 184
Cdd:PRK02496 131 KDDTEEVIRRRLEVYREQTAPLIDYYRDRQKLLTIDGNQSVEAVTTELKAA 181
|
|
| PRK13808 |
PRK13808 |
adenylate kinase; Provisional |
16-188 |
4.10e-30 |
|
adenylate kinase; Provisional
Pssm-ID: 172341 [Multi-domain] Cd Length: 333 Bit Score: 112.67 E-value: 4.10e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 16 IRAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNG 53
Cdd:PRK13808 1 MRLILLGPPGAGKGTQaqrlvqqygivqlstgdmlraavaagtpvglkakdimasgglVPDEVVVGIISDRIEQPDAANG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 54 FLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIHPKSgrsyheefnppkepmkddiTGEPLirR 133
Cdd:PRK13808 81 FILDGFPRTVPQAEALDALLKDKQLKLDAVVELRVNEGALLARVETRVAEMRA-------------------RGEEV--R 139
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 982742441 134 SDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASI---LAAFSKA 188
Cdd:PRK13808 140 ADDTPEVLAKRLASYRAQTEPLVHYYSEKRKLLTVDGMMTIDEVTREIgrvLAAVGAA 197
|
|
| PRK14528 |
PRK14528 |
adenylate kinase; Provisional |
17-182 |
3.35e-29 |
|
adenylate kinase; Provisional
Pssm-ID: 172994 [Multi-domain] Cd Length: 186 Bit Score: 106.63 E-value: 3.35e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETPLCKNGF 54
Cdd:PRK14528 3 NIIFMGPPGAGKGTQakilcerlsipqistgdilreavknqtamgieakrymdagdlVPDSVVIGIIKDRIREADCKNGF 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 55 LLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIhpKSGrsyheefnppkepmkdditgeplirRS 134
Cdd:PRK14528 83 LLDGFPRTVEQADALDALLKNEGKSIDKAINLEVPDGELLKRLLGRAE--IEG-------------------------RA 135
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 982742441 135 DDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASIL 182
Cdd:PRK14528 136 DDNEATIKNRLDNYNKKTLPLLDFYAAQKKLSQVNGVGSLEEVTSLIQ 183
|
|
| PRK14526 |
PRK14526 |
adenylate kinase; Provisional |
19-187 |
4.21e-28 |
|
adenylate kinase; Provisional
Pssm-ID: 172992 [Multi-domain] Cd Length: 211 Bit Score: 104.55 E-value: 4.21e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 19 VLLGPPGAGKGT------------------------------------------QVSDEMVVELIEKNLETPLCKNGFLL 56
Cdd:PRK14526 4 VFLGPPGSGKGTiakilsnelnyyhistgdlfrenilnstplgkeikqivengqLVPDSITIKIVEDKINTIKNNDNFIL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 57 DGFPRTVRQAEMLDDLMEKRKekldsVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDD 136
Cdd:PRK14526 84 DGFPRNINQAKALDKFLPNIK-----IINFLIDEELLIKRLSGRRICKSCNNIFNIYTLPTKEKGICDVCKGDLYQRKDD 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 982742441 137 NEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSK 187
Cdd:PRK14526 159 KEESLKTRLQEYKLQTKPLIEFYSKCNRLNNIDASKDIDEVKKKLIEIISK 209
|
|
| PRK14531 |
PRK14531 |
adenylate kinase; Provisional |
17-186 |
4.23e-26 |
|
adenylate kinase; Provisional
Pssm-ID: 172997 [Multi-domain] Cd Length: 183 Bit Score: 98.34 E-value: 4.23e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 17 RAVLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLETpLCKNGF 54
Cdd:PRK14531 4 RLLFLGPPGAGKGTQaarlcaahglrhlstgdllrsevaagsalgqeaeavmnrgelVSDALVLAIVESQLKA-LNSGGW 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 55 LLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRlihpksgrsyheefnppkepmkdditgepliRRS 134
Cdd:PRK14531 83 LLDGFPRTVAQAEALEPLLEELKQPIEAVVLLELDDAVLIERLLAR-------------------------------GRA 131
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 982742441 135 DDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFS 186
Cdd:PRK14531 132 DDNEAVIRNRLEVYREKTAPLIDHYRQRGLLQSVEAQGSIEAITERIEKVLA 183
|
|
| PRK14527 |
PRK14527 |
adenylate kinase; Provisional |
19-186 |
1.40e-25 |
|
adenylate kinase; Provisional
Pssm-ID: 237745 [Multi-domain] Cd Length: 191 Bit Score: 97.55 E-value: 1.40e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 19 VLLGPPGAGKGTQ------------------------------------------VSDEMVVELIEKNLeTPLCKNGFLL 56
Cdd:PRK14527 10 IFLGPPGAGKGTQaerlaqelglkklstgdilrdhvargtelgqrakpimeagdlVPDELILALIRDEL-AGMEPVRVIF 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 57 DGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLihpksgrsyHEEfnppkepmkdditgepliRRSDD 136
Cdd:PRK14527 89 DGFPRTLAQAEALDRLLEELGARLLAVVLLEVPDEELIRRIVERA---------RQE------------------GRSDD 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 982742441 137 NEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFS 186
Cdd:PRK14527 142 NEETVRRRQQVYREQTQPLVDYYEARGHLKRVDGLGTPDEVYARILKALG 191
|
|
| PLN02842 |
PLN02842 |
nucleotide kinase |
29-187 |
2.51e-23 |
|
nucleotide kinase
Pssm-ID: 178435 [Multi-domain] Cd Length: 505 Bit Score: 96.08 E-value: 2.51e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 29 GTQVSDEMVVELIEKNLETP-LCKNGFLLDGFPRTVRQAEMLDDLmekrKEKLDSVIEFSIPDSLLIRRITGRLIHPKSG 107
Cdd:PLN02842 53 GRLVPDEIVIAMVTGRLSREdAKEKGWLLDGYPRSFAQAQSLEKL----KIRPDIFILLDVPDEILIDRCVGRRLDPVTG 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 108 RSYHEEFNPPKEPmkdDITGEpLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKrgIHSAIDASQTPDVVFASILAAFSK 187
Cdd:PLN02842 129 KIYHIKNFPPESE---EIKAR-LITRPDDTEEKVKARLQIYKKNAEAILSTYSD--IMVKIDGNRPKEVVFEEISSLLSQ 202
|
|
| UMP_CMP_kin_fam |
TIGR01359 |
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of ... |
21-186 |
8.12e-23 |
|
UMP-CMP kinase family; This subfamily of the adenylate kinase superfamily contains examples of UMP-CMP kinase, as well as others proteins with unknown specificity, some currently designated adenylate kinase. All known members are eukaryotic.
Pssm-ID: 273576 [Multi-domain] Cd Length: 185 Bit Score: 90.12 E-value: 8.12e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 21 LGPPGAGKGTQ-------------------------------------------VSDEMVVELIEKNLETPLCKNGFLLD 57
Cdd:TIGR01359 5 LGGPGSGKGTQcakivenfgfthlsagdllraeikregsengsliesyikegkiVPSEVTVELLKKAIQEDGSSKKFLID 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 58 GFPRTVRQAEMLDDLMEKrKEKLDSVIEFSIPDSLLIRRITGRliHPKSGrsyheefnppkepmkdditgeplirRSDDN 137
Cdd:TIGR01359 85 GFPRNEENLEAWEKLMDN-KVNFKFVLFFDCPEETMIKRLLKR--GQTSG-------------------------RVDDN 136
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 982742441 138 EKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFS 186
Cdd:TIGR01359 137 IETLKKRFRTYNEETLPIIEHFENKGKVKEINAEGSVEEVFEDVEKIFA 185
|
|
| PLN02459 |
PLN02459 |
probable adenylate kinase |
2-163 |
1.04e-21 |
|
probable adenylate kinase
Pssm-ID: 215253 [Multi-domain] Cd Length: 261 Bit Score: 88.75 E-value: 1.04e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 2 APSVPAAEPEYPKGIRAVLLGPPGAGKGTQ------------------------------------------VSDEMVVE 39
Cdd:PLN02459 16 LASACDRSLAKGRNVNWVFLGCPGVGKGTYasrlskllgvphiatgdlvreeikssgplgaqlkeivnqgklVPDEIIFS 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 40 LIEKNLETPLCK--NGFLLDGFPRTVRQAEMLDDLMEkrkekLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYH------ 111
Cdd:PLN02459 96 LLSKRLEAGEEEgeSGFILDGFPRTVRQAEILEGVTD-----IDLVVNLKLREEVLVEKCLGRRICSECGKNFNvadidl 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 982742441 112 -----------EEFNPPKEPMKDditgepLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRG 163
Cdd:PLN02459 171 kgedgrpgivmPPLLPPPECASK------LITRADDTEEVVKARLRVYKEESQPVEDFYRKRG 227
|
|
| PTZ00088 |
PTZ00088 |
adenylate kinase 1; Provisional |
26-164 |
7.48e-18 |
|
adenylate kinase 1; Provisional
Pssm-ID: 240262 [Multi-domain] Cd Length: 229 Bit Score: 77.92 E-value: 7.48e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 26 AGKGTQVSDEMVVELIEKNLETPL--CKNGFLLDGFPRTVRQAEMLDDLmekrkEKLDSVIEFSIPDSLLIRRITGRLIH 103
Cdd:PTZ00088 59 VTSGNLVPDNLVIAIVKDEIAKVTddCFKGFILDGFPRNLKQCKELGKI-----TNIDLFVNIYLPRNILIKKLLGRRIC 133
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 982742441 104 PKSGRSYH------EEFN-PPKEPMKDDIT--GEP-LIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGI 164
Cdd:PTZ00088 134 NTCNRNFNiahirsDPYDmPPILPPADCEGckGNPkLQKRSDDTEEIVAHRLNTYESTNSPIIQFFKNENC 204
|
|
| ADK_lid |
pfam05191 |
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular ... |
100-135 |
3.02e-17 |
|
Adenylate kinase, active site lid; Comparisons of adenylate kinases have revealed a particular divergence in the active site lid. In some organizms, particularly the Gram-positive bacteria, residues in the lid domain have been mutated to cysteines and these cysteine residues are responsible for the binding of a zinc ion. The bound zinc ion in the lid domain, is clearly structurally homologous to Zinc-finger domains. However, it is unclear whether the adenylate kinase lid is a novel zinc-finger DNA/RNA binding domain, or that the lid bound zinc serves a purely structural function.
Pssm-ID: 461578 [Multi-domain] Cd Length: 36 Bit Score: 71.34 E-value: 3.02e-17
10 20 30
....*....|....*....|....*....|....*.
gi 982742441 100 RLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSD 135
Cdd:pfam05191 1 RRVCPKCGRIYHVYFNPPKVEGVCDVCGGELVQRDD 36
|
|
| aden_kin_iso1 |
TIGR01360 |
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. ... |
7-188 |
4.22e-17 |
|
adenylate kinase, isozyme 1 subfamily; Members of this family are adenylate kinase, EC 2.7.4.3. This clade is found only in eukaryotes and includes human adenylate kinase isozyme 1 (myokinase). Within the adenylate kinase superfamily, this set appears specifically closely related to a subfamily of eukaryotic UMP-CMP kinases (TIGR01359), rather than to the large clade of bacterial, archaeal, and eukaryotic adenylate kinase family members in TIGR01351.
Pssm-ID: 130427 [Multi-domain] Cd Length: 188 Bit Score: 75.24 E-value: 4.22e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 7 AAEPEYPKGIRAVLlgppgaGKGTQVSDEMVVELIEKNLETPLCKN-GFLLDGFPRTVRQAEMLddlmEKRKEKLDSVIE 85
Cdd:TIGR01360 43 ASGSERGKQLQAIM------ESGDLVPLDTVLDLLKDAMVAALGTSkGFLIDGYPREVKQGEEF----ERRIGPPTLVLY 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 86 FSIPDSLLIRRITGRliHPKSGRSyheefnppkepmkdditgeplirrsDDNEKALKIRLQAYHTQTTPLIEYYRKRGIH 165
Cdd:TIGR01360 113 FDCSEDTMVKRLLKR--AETSGRV-------------------------DDNEKTIKKRLETYYKATEPVIAYYETKGKL 165
|
170 180
....*....|....*....|...
gi 982742441 166 SAIDASQTPDVVFASILAAFSKA 188
Cdd:TIGR01360 166 RKINAEGTVDDVFLQVCTAIDKL 188
|
|
| PRK14529 |
PRK14529 |
adenylate kinase; Provisional |
28-153 |
3.82e-12 |
|
adenylate kinase; Provisional
Pssm-ID: 237746 [Multi-domain] Cd Length: 223 Bit Score: 62.43 E-value: 3.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 28 KGTQVSDEMVVELIEKNLETPlCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLI----- 102
Cdd:PRK14529 55 RGDLVPDDITIPMILETLKQD-GKNGWLLDGFPRNKVQAEKLWEALQKEGMKLDYVIEILLPREVAKNRIMGRRLckndn 133
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 982742441 103 -HPKSgrSYHEEFNPPKEpmKDDITGEPLIRRSDD-NEKALKIRLQAYHTQTT 153
Cdd:PRK14529 134 nHPNN--IFIDAIKPDGD--VCRVCGGELSTRADDqDEEAINKRHDIYYDTET 182
|
|
| AAA_17 |
pfam13207 |
AAA domain; |
21-110 |
4.96e-09 |
|
AAA domain;
Pssm-ID: 463810 [Multi-domain] Cd Length: 136 Bit Score: 52.24 E-value: 4.96e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 21 LGPPGAGKGTQ----------------------------------------VSDEMVVELIEKNLETPLCKNGFLLDGFP 60
Cdd:pfam13207 1 TGVPGSGKTTQlkklaeklgfphisagdllreeakerglvedrdemrklplEPQKELQKLAAERIAEEAGEGGVIVDGHP 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 982742441 61 RTVRQAEMLDDLMEKRKEKL--DSVIEFSIPDSLLIRRitgRLIHPKSGRSY 110
Cdd:pfam13207 81 RIKTPAGYLPGLPVEVLRELkpDAIILLEADPEEILER---RLKDRTRGRDD 129
|
|
| PLN02200 |
PLN02200 |
adenylate kinase family protein |
28-186 |
5.29e-09 |
|
adenylate kinase family protein
Pssm-ID: 215125 [Multi-domain] Cd Length: 234 Bit Score: 53.74 E-value: 5.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 28 KGTQVSDEMVVELIEKNLETPLcKNGFLLDGFPRTVRQAEMLDDLMekrKEKLDSVIEFSIPDSLLIRRITGRlihpKSG 107
Cdd:PLN02200 98 EGKIVPSEVTVKLIQKEMESSD-NNKFLIDGFPRTEENRIAFERII---GAEPNVVLFFDCPEEEMVKRVLNR----NQG 169
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 982742441 108 rsyheefnppkepmkdditgeplirRSDDNEKALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFS 186
Cdd:PLN02200 170 -------------------------RVDDNIDTIKKRLKVFNALNLPVIDYYSKKGKLYTINAVGTVDEIFEQVRPIFA 223
|
|
| BRO1_Rhophilin |
cd09244 |
Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin and related domains; ... |
114-190 |
6.61e-03 |
|
Protein-interacting Bro1-like domain of RhoA-binding protein Rhophilin and related domains; This family contains the Bro1-like domain of RhoA-binding proteins, Rhophilin-1 and -2, and related domains. It belongs to the BRO1_Alix_like superfamily which also includes the Bro1-like domains of mammalian Alix (apoptosis-linked gene-2 interacting protein X), His-Domain type N23 protein tyrosine phosphatase (HD-PTP, also known as PTPN23), Brox, Bro1 and Rim20 (also known as PalA) from Saccharomyces cerevisiae, Ustilago maydis Rim23 (also known as PalC), and related domains. Rhophilin-1 and -2 bind both GDP- and GTP-bound RhoA. Bro1-like domains are boomerang-shaped, and part of the domain is a tetratricopeptide repeat (TPR)-like structure. In addition to this Bro1-like domain, Rhophilin-1 and -2, contain an N-terminal Rho-binding domain and a C-terminal PDZ (PS.D.-95, Disc-large, ZO-1) domain. Their PDZ domains have limited homology. Rhophilin-1 and -2 have different activities. The Drosophila knockout of Rhophilin-1 is embryonic lethal, suggesting an essential role in embryonic development. Roles of Rhophilin-2 may include limiting stress fiber formation or increasing the turnover of F-actin in the absence of high levels of RhoA signaling activity. The isolated Bro1-like domain of Rhophilin-1 binds human immunodeficiency virus type 1 (HIV-1) nucleocapsid. This family lacks the V-shaped (V) domain found in many members of the BRO1_Alix _like superfamily.
Pssm-ID: 185767 Cd Length: 350 Bit Score: 36.55 E-value: 6.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 982742441 114 FNPPKEPMK------DDITGEPLIRRSDDNEKA-LKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFS 186
Cdd:cd09244 74 FFPPDRSLGiyfhwyDSLTGVPSVQRSVAFEKAsVLFNIGALYTQIGAKQDRTTEEGIEAAVDAFQRAAGAFNYLRENFS 153
|
....
gi 982742441 187 KATS 190
Cdd:cd09244 154 NAPS 157
|
|
| |
