|
Name |
Accession |
Description |
Interval |
E-value |
| Nucleic_acid_bd |
pfam13820 |
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ... |
48-190 |
2.30e-61 |
|
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.
:
Pssm-ID: 463988 Cd Length: 143 Bit Score: 206.51 E-value: 2.30e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSV 127
Cdd:pfam13820 1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 970841901 128 QIEGEGAINLALA---QNRSQDVRMnGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNV 190
Cdd:pfam13820 79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLISDALPLHLRLAESGEY 143
|
|
| Med15 super family |
cl26621 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
520-838 |
2.94e-09 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
The actual alignment was detected with superfamily member pfam09606:
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 62.33 E-value: 2.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 520 SAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVqhAGGQGAGPPQNQMQVSHGPPnmmQPSLMGIHGNMNNQQAGTs 599
Cdd:pfam09606 54 SKKAAQQQQPQGGQGNGGMGGGQQGMPDPINALQNL--AGQGTRPQMMGPMGPGPGGP---MGQQMGGPGTASNLLASL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 600 GVPQVNL------SNMQGQPQQGPPSQLMGMHQQIVPSQGQ-MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGP 672
Cdd:pfam09606 128 GRPQMPMggagfpSQMSRVGRMQPGGQAGGMMQPSSGQPGSgTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 673 S-PQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNM 751
Cdd:pfam09606 208 GmPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPMGPP 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 752 QgnmvQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPhmaQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPP 831
Cdd:pfam09606 288 G----QQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQ---QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGL 360
|
....*..
gi 970841901 832 HVQAMQG 838
Cdd:pfam09606 361 GANPMQR 367
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
1056-1302 |
3.57e-06 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 3.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1056 PPRGPLNPDSQRMPmqQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1135
Cdd:PHA03247 2744 VPAGPATPGGPARP--ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1136 SG---------SEAPSVPGGPNNMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1204
Cdd:PHA03247 2822 ASpagplppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1205 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNPttlkaig 1284
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP------- 2960
|
250
....*....|....*...
gi 970841901 1285 qAPSNLTMNPSNFATPQT 1302
Cdd:PHA03247 2961 -QPWLGALVPGRVAVPRF 2977
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
152-544 |
3.51e-05 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 3.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 152 PMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPElqPRTPRPASQSDAMDPLlsglhiqqqsh 231
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP--PQRPRRRAARPTVGSL----------- 2695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 232 psGSLAPPHHPMQPVSvnrqmnPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQ 311
Cdd:PHA03247 2696 --TSLADPPPPPPTPE------PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPP 2767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 312 VPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQqLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFP 391
Cdd:PHA03247 2768 APAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV-LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP 2846
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 392 QMSNP-GQFTAPqmkslqGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPqnnPLPQGFQQP 470
Cdd:PHA03247 2847 PPSLPlGGSVAP------GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP---PQPQAPPPP 2917
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 970841901 471 VSSPGRNPMVQQGNVPPnfmvmqqqPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNS 544
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPP--------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Nucleic_acid_bd |
pfam13820 |
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ... |
48-190 |
2.30e-61 |
|
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.
Pssm-ID: 463988 Cd Length: 143 Bit Score: 206.51 E-value: 2.30e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSV 127
Cdd:pfam13820 1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 970841901 128 QIEGEGAINLALA---QNRSQDVRMnGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNV 190
Cdd:pfam13820 79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLISDALPLHLRLAESGEY 143
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
520-838 |
2.94e-09 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 62.33 E-value: 2.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 520 SAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVqhAGGQGAGPPQNQMQVSHGPPnmmQPSLMGIHGNMNNQQAGTs 599
Cdd:pfam09606 54 SKKAAQQQQPQGGQGNGGMGGGQQGMPDPINALQNL--AGQGTRPQMMGPMGPGPGGP---MGQQMGGPGTASNLLASL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 600 GVPQVNL------SNMQGQPQQGPPSQLMGMHQQIVPSQGQ-MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGP 672
Cdd:pfam09606 128 GRPQMPMggagfpSQMSRVGRMQPGGQAGGMMQPSSGQPGSgTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 673 S-PQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNM 751
Cdd:pfam09606 208 GmPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPMGPP 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 752 QgnmvQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPhmaQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPP 831
Cdd:pfam09606 288 G----QQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQ---QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGL 360
|
....*..
gi 970841901 832 HVQAMQG 838
Cdd:pfam09606 361 GANPMQR 367
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1056-1302 |
3.57e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 3.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1056 PPRGPLNPDSQRMPmqQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1135
Cdd:PHA03247 2744 VPAGPATPGGPARP--ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1136 SG---------SEAPSVPGGPNNMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1204
Cdd:PHA03247 2822 ASpagplppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1205 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNPttlkaig 1284
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP------- 2960
|
250
....*....|....*...
gi 970841901 1285 qAPSNLTMNPSNFATPQT 1302
Cdd:PHA03247 2961 -QPWLGALVPGRVAVPRF 2977
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
152-544 |
3.51e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 3.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 152 PMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPElqPRTPRPASQSDAMDPLlsglhiqqqsh 231
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP--PQRPRRRAARPTVGSL----------- 2695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 232 psGSLAPPHHPMQPVSvnrqmnPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQ 311
Cdd:PHA03247 2696 --TSLADPPPPPPTPE------PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPP 2767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 312 VPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQqLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFP 391
Cdd:PHA03247 2768 APAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV-LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP 2846
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 392 QMSNP-GQFTAPqmkslqGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPqnnPLPQGFQQP 470
Cdd:PHA03247 2847 PPSLPlGGSVAP------GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP---PQPQAPPPP 2917
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 970841901 471 VSSPGRNPMVQQGNVPPnfmvmqqqPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNS 544
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPP--------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
612-755 |
6.62e-05 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 47.88 E-value: 6.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 612 QPQQGPPSQ-LMGMHQQIVPSQGQMVQQQGTLNPQNPMilsraqLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQ 690
Cdd:TIGR01628 384 QLPMGSPMGgAMGQPPYYGQGPQQQFNGQPLGWPRMSM------MPTPMGPGGPLRPNGLAPMNAVRAPSRNAQNAAQKP 457
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 970841901 691 MMAPHNQMMGPQGQVLLQQNPmieqimtnqmqgnkQQFNTQNQSNVMPGPAQIMRGPTPNMQGNM 755
Cdd:TIGR01628 458 PMQPVMYPPNYQSLPLSQDLP--------------QPQSTASQGGQNKKLAQVLASATPQMQKQV 508
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1107-1402 |
1.12e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 44.14 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1107 SNSRKMVYQESPQNPSSSPLAEmaslpeASGSEAPSVPGGpnnMPSHVVLPQNQLM--MTGPK------PGPSPLSATQG 1178
Cdd:pfam05109 414 TTTHKVIFSKAPESTTTSPTLN------TTGFAAPNTTTG---LPSSTHVPTNLTApaSTGPTvstadvTSPTPAGTTSG 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1179 ATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQ-TPNNRPPS---TEPSE--ISLSPERLNASIAGLF 1252
Cdd:pfam05109 485 ASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTpTPNATSPTlgkTSPTSavTTPTPNATSPTPAVTT 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1253 P-PQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRR 1331
Cdd:pfam05109 565 PtPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSM 644
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 970841901 1332 SSPGSSRKTTPSPGRQN---SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGlnPQNST 1402
Cdd:pfam05109 645 SLRPSSISETLSPSTSDnstSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASG--PGNSS 716
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Nucleic_acid_bd |
pfam13820 |
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding ... |
48-190 |
2.30e-61 |
|
Putative nucleic acid-binding region; This is a family of putative nucleic acid-binding proteins. Several members are annotated as being nuclear receptor coactivator 6 proteins but this could not be confirmed.
Pssm-ID: 463988 Cd Length: 143 Bit Score: 206.51 E-value: 2.30e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 48 IFVAFKGNIDDkdFKWKLDAILKNVPNLLHMESSKLKVQKVEPWNSVRVTFNIPREAAERLRILAQSNNQQLRDLGILSV 127
Cdd:pfam13820 1 TFLAVKGNLRM--FQEKLDSIRENVAELLRTEKSKLKVRKVEPWNSVRVTFSIPREAALRLRLLAQHNDPRLRDLGILSV 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 970841901 128 QIEGEGAINLALA---QNRSQDVRMnGPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNV 190
Cdd:pfam13820 79 QIEGEGPINLTLAtmvQNPADDIIL-GCSTQLNSQRAEQGWTMLSALGLISDALPLHLRLAESGEY 143
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
520-838 |
2.94e-09 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 62.33 E-value: 2.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 520 SAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVqhAGGQGAGPPQNQMQVSHGPPnmmQPSLMGIHGNMNNQQAGTs 599
Cdd:pfam09606 54 SKKAAQQQQPQGGQGNGGMGGGQQGMPDPINALQNL--AGQGTRPQMMGPMGPGPGGP---MGQQMGGPGTASNLLASL- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 600 GVPQVNL------SNMQGQPQQGPPSQLMGMHQQIVPSQGQ-MVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGP 672
Cdd:pfam09606 128 GRPQMPMggagfpSQMSRVGRMQPGGQAGGMMQPSSGQPGSgTPNQMGPNGGPGQGQAGGMNGGQQGPMGGQMPPQMGVP 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 673 S-PQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNM 751
Cdd:pfam09606 208 GmPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPMGPP 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 752 QgnmvQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPhmaQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPP 831
Cdd:pfam09606 288 G----QQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQ---QQMNQSVGQGGQVVALGGLNHLETWNPGNFGGL 360
|
....*..
gi 970841901 832 HVQAMQG 838
Cdd:pfam09606 361 GANPMQR 367
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
272-748 |
2.71e-06 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 52.70 E-value: 2.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 272 QQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGwkKAPLPG 351
Cdd:pfam09606 64 QGGQGNGGMGGGQQGMPDPINALQNLAGQGTRPQMMGPMGPGPGGPMGQQMGGPGTASNLLASLGRPQMPMG--GAGFPS 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 352 PMQQQLQARPSLATvqtpsHPPPPYPFGSQQASQAHTNFPQMSnPGQFTAPQMKSLQGGPSRVPTPLQ------------ 419
Cdd:pfam09606 142 QMSRVGRMQPGGQA-----GGMMQPSSGQPGSGTPNQMGPNGG-PGQGQAGGMNGGQQGPMGGQMPPQmgvpgmpgpada 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 420 QPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMgpRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMvmqqqppnq 499
Cdd:pfam09606 216 GAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQ--QQGQQSQLGMGINQMQQMPQGVGGGAGQGGPGQPM--------- 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 500 gpqslhPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMqvshGPPNM 579
Cdd:pfam09606 285 ------GPPGQQPGAMPNVMSIGDQNNYQQQQTRQQQQQQGGNHPAAHQQQMNQSVGQGGQVVALGGLNHL----ETWNP 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 580 MQPSLMGIHGnMNNQQAGTSGVPQVnlSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQG 659
Cdd:pfam09606 355 GNFGGLGANP-MQRGQPGMMSSPSP--VPGQQVRQVTPNQFMRQSPQPSVPSPQGPGSQPPQSHPGGMIPSPALIPSPSP 431
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 660 QMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQsnvMPG 739
Cdd:pfam09606 432 QMSQQPAQQRTIGQDSPGGSLNTPGQSAVNSPLNPQEEQLYREKYRQLTKYIEPLKRMIAKMENDPGDIDKMNK---MKR 508
|
....*....
gi 970841901 740 PAQIMRGPT 748
Cdd:pfam09606 509 LLEILSNPS 517
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
612-782 |
3.26e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 52.35 E-value: 3.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 612 QPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQnpmilsraQLMPQGQMMVNPPSQNLGPSPQRmtppkqmLSQQGPQM 691
Cdd:pfam09770 209 KPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQ--------QQQPQQQPQQPQQHPGQGHPVTI-------LQRPQSPQ 273
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 692 MAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQsnvMPGPAQIMRGPTPNMQgnmvqftGQMSGQMLPQQG 771
Cdd:pfam09770 274 PDPAQPSIQPQAQQFHQQPPPVPVQPTQILQNPNRLSAARVG---YPQNPQPGVQPAPAHQ-------AHRQQGSFGRQA 343
|
170
....*....|.
gi 970841901 772 PVNNSPSQVMG 782
Cdd:pfam09770 344 PIITHPQQLAQ 354
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1056-1302 |
3.57e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 3.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1056 PPRGPLNPDSQRMPmqQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEA 1135
Cdd:PHA03247 2744 VPAGPATPGGPARP--ARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPA 2821
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1136 SG---------SEAPSVPGGPNNMPSHVVLPQNQLMMTGP--KPGPSPLSATQGATPQQPPVNSLPSshghhfPNVAAPT 1204
Cdd:PHA03247 2822 ASpagplppptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDvrRRPPSRSPAAKPAAPARPPVRRLAR------PAVSRST 2895
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1205 QTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLnasiaglfPPQINIPLPPRPNLNRGFDQQGLNPttlkaig 1284
Cdd:PHA03247 2896 ESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP--------PPRPQPPLAPTTDPAGAGEPSGAVP------- 2960
|
250
....*....|....*...
gi 970841901 1285 qAPSNLTMNPSNFATPQT 1302
Cdd:PHA03247 2961 -QPWLGALVPGRVAVPRF 2977
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
455-654 |
2.97e-05 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 49.26 E-value: 2.97e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 455 PRPPQNNPLPQGFQQPVSSPGRN---------PMVQQGNVPPNfmvmQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQAN 525
Cdd:pfam09770 170 AAAPAPAPQPAAQPASLPAPSRKmmsleeveaAMRAQAKKPAQ----QPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 526 PNFMQGQVPSTtattPGNSGAPQ-LQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPslMGIHGNMNNQQAGTSGVPQv 604
Cdd:pfam09770 246 PQQQPQQPQQH----PGQGHPVTiLQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQP--TQILQNPNRLSAARVGYPQ- 318
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 970841901 605 nlsNMQGQPQQGPPSQlmgmHQQIVPSQGQMVQQQgtLNPQNPMILSRAQ 654
Cdd:pfam09770 319 ---NPQPGVQPAPAHQ----AHRQQGSFGRQAPII--THPQQLAQLSEEE 359
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
152-544 |
3.51e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 3.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 152 PMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPElqPRTPRPASQSDAMDPLlsglhiqqqsh 231
Cdd:PHA03247 2629 PSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSP--PQRPRRRAARPTVGSL----------- 2695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 232 psGSLAPPHHPMQPVSvnrqmnPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQ 311
Cdd:PHA03247 2696 --TSLADPPPPPPTPE------PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPP 2767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 312 VPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQqLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFP 391
Cdd:PHA03247 2768 APAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAV-LAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPP 2846
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 392 QMSNP-GQFTAPqmkslqGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPqnnPLPQGFQQP 470
Cdd:PHA03247 2847 PPSLPlGGSVAP------GGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP---PQPQAPPPP 2917
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 970841901 471 VSSPGRNPMVQQGNVPPnfmvmqqqPPNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNS 544
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPP--------PPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPA 2983
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1085-1559 |
3.91e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.17 E-value: 3.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1085 PASVPPSPDkQRMPMPVNTPlgsnsrkmvyqeSPQNPSSSPLAEMASLPEASGSeaPSVPGGPNNMPSHVV----LPQNQ 1160
Cdd:PHA03247 2557 PAAPPAAPD-RSVPPPRPAP------------RPSEPAVTSRARRPDAPPQSAR--PRAPVDDRGDPRGPAppspLPPDT 2621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1161 LMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLS 1240
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADP 2701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1241 PERLNASIAGLFPPQINIPLPPRPNLNRgfdqQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGA 1320
Cdd:PHA03247 2702 PPPPPTPEPAPHALVSATPLPPGPAAAR----QASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAA 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1321 TKRASPSNSRRSSPGSSRKTTPS---PGRQNSKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGLN 1397
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSpwdPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1398 PQNSTVSVAAVGGVVEDNKESLNVPQDSdcqnsqsrkeqvnIELKAVPAQEVKMVVPEDQSKKDGQPSDPNK--LPSVEE 1475
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR-------------LARPAVSRSTESFALPPDQPERPPQPQAPPPpqPQPQPP 2924
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1476 NKNLVSPAMREAPTSLSQL---LDNSGAPNVTIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQDLSSSKEPSNSLNLPHS 1552
Cdd:PHA03247 2925 PPPQPQPPPPPPPRPQPPLaptTDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRV 3004
|
....*..
gi 970841901 1553 NELCSSL 1559
Cdd:PHA03247 3005 SSWASSL 3011
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
612-755 |
6.62e-05 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 47.88 E-value: 6.62e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 612 QPQQGPPSQ-LMGMHQQIVPSQGQMVQQQGTLNPQNPMilsraqLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQ 690
Cdd:TIGR01628 384 QLPMGSPMGgAMGQPPYYGQGPQQQFNGQPLGWPRMSM------MPTPMGPGGPLRPNGLAPMNAVRAPSRNAQNAAQKP 457
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 970841901 691 MMAPHNQMMGPQGQVLLQQNPmieqimtnqmqgnkQQFNTQNQSNVMPGPAQIMRGPTPNMQGNM 755
Cdd:TIGR01628 458 PMQPVMYPPNYQSLPLSQDLP--------------QPQSTASQGGQNKKLAQVLASATPQMQKQV 508
|
|
| PABP-1234 |
TIGR01628 |
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ... |
619-770 |
1.81e-04 |
|
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.
Pssm-ID: 130689 [Multi-domain] Cd Length: 562 Bit Score: 46.34 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 619 SQLMGMHQQIVPSQGQMVQqqgtLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMtPPKQMLSQQGPQMMAPhnqm 698
Cdd:TIGR01628 369 AHLQDQFMQLQPRMRQLPM----GSPMGGAMGQPPYYGQGPQQQFNGQPLGWPRMSMMP-TPMGPGGPLRPNGLAP---- 439
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 970841901 699 MGPQGQVLLQQNPMIEQimtNQMQGNKQQFNTQNQSNVMPGPAQimrGPTPNMQGNMvQFTGQMSGQMLPQQ 770
Cdd:TIGR01628 440 MNAVRAPSRNAQNAAQK---PPMQPVMYPPNYQSLPLSQDLPQP---QSTASQGGQN-KKLAQVLASATPQM 504
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1029-1422 |
2.36e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 2.36e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1029 QQQQMMMMLMMQQDPKSVRLPVSQNVHPPR----GPLNPDSQRMPMQQSGSVPVMVSLQG--PASVPPSPDKQRMPMPvn 1102
Cdd:PHA03247 2581 AVTSRARRPDAPPQSARPRAPVDDRGDPRGpappSPLPPDTHAPDPPPPSPSPAANEPDPhpPPTVPPPERPRDDPAP-- 2658
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1103 tPLGSNSRKMVYQESPQNPSSSP------LAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSAT 1176
Cdd:PHA03247 2659 -GRVSRPRRARRLGRAAQASSPPqrprrrAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPA 2737
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1177 QGATPQQPPVNSLPsshghhfpnvAAPTQTSRPKTPNrASPRPYYPQTPNNRPP--STEPSEISLSPERLNASIAGLFPP 1254
Cdd:PHA03247 2738 APAPPAVPAGPATP----------GGPARPARPPTTA-GPPAPAPPAAPAAGPPrrLTRPAVASLSESRESLPSPWDPAD 2806
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1255 QINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSnltmnPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRRSSP 1334
Cdd:PHA03247 2807 PPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPP-----PPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARP 2881
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1335 GSSRKTTPSPGRQNSK--APKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPnnSGLNPQNSTVSVAAVGGVV 1412
Cdd:PHA03247 2882 PVRRLARPAVSRSTESfaLPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ--PPLAPTTDPAGAGEPSGAV 2959
|
410
....*....|
gi 970841901 1413 EDNKESLNVP 1422
Cdd:PHA03247 2960 PQPWLGALVP 2969
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
929-1490 |
2.42e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 46.47 E-value: 2.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 929 DLNTPDTRPAgleeadqpPLPGEQGINLDNSGPKLPEFSNRP--PGYPS-QPVEQRPLQQMPPQLMQHVAPPPQPPQQQP 1005
Cdd:PHA03247 2565 DRSVPPPRPA--------PRPSEPAVTSRARRPDAPPQSARPraPVDDRgDPRGPAPPSPLPPDTHAPDPPPPSPSPAAN 2636
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1006 QPQLPQQQQPPPPSQPQSQQQqqqqqqmmmmlmmqqdPKSVRLP--VSQNVHPPRGPLNPDSQRMPMQQSGSVPVmVSLQ 1083
Cdd:PHA03247 2637 EPDPHPPPTVPPPERPRDDPA----------------PGRVSRPrrARRLGRAAQASSPPQRPRRRAARPTVGSL-TSLA 2699
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1084 GPASVPPSPDKQRMPMPVNTPL--GSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEA-PSVPGGPNNmPSHVVLPQNQ 1160
Cdd:PHA03247 2700 DPPPPPPTPEPAPHALVSATPLppGPAAARQASPALPAAPAPPAVPAGPATPGGPARPArPPTTAGPPA-PAPPAAPAAG 2778
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1161 LMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVaAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLS 1240
Cdd:PHA03247 2779 PPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL-PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA 2857
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1241 PERLNASIAGLFPPQINIPLPPRPNLNRgfdqqglnpTTLKAIGQAPSNLTMNPSNFATPQTHKLDsvvvnSGKQSNSGA 1320
Cdd:PHA03247 2858 PGGDVRRRPPSRSPAAKPAAPARPPVRR---------LARPAVSRSTESFALPPDQPERPPQPQAP-----PPPQPQPQP 2923
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1321 TKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQ-NVELPRNVLVSPTPLANPPVPGSFPNNSGLNPQ 1399
Cdd:PHA03247 2924 PPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPgRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSR 3003
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1400 NSTVSVAAVGGVVEDN-----KESLNVPQDSDCQNSQSRKEQVNIELkavpaqevkmvvpeDQSKKDGQPSDPNKLPSVE 1474
Cdd:PHA03247 3004 VSSWASSLALHEETDPppvslKQTLWPPDDTEDSDADSLFDSDSERS--------------DLEALDPLPPEPHDPFAHE 3069
|
570
....*....|....*.
gi 970841901 1475 ENKNLVSPAMREAPTS 1490
Cdd:PHA03247 3070 PDPATPEAGARESPSS 3085
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
1107-1402 |
1.12e-03 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 44.14 E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1107 SNSRKMVYQESPQNPSSSPLAEmaslpeASGSEAPSVPGGpnnMPSHVVLPQNQLM--MTGPK------PGPSPLSATQG 1178
Cdd:pfam05109 414 TTTHKVIFSKAPESTTTSPTLN------TTGFAAPNTTTG---LPSSTHVPTNLTApaSTGPTvstadvTSPTPAGTTSG 484
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1179 ATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQ-TPNNRPPS---TEPSE--ISLSPERLNASIAGLF 1252
Cdd:pfam05109 485 ASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPAVTTpTPNATSPTlgkTSPTSavTTPTPNATSPTPAVTT 564
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1253 P-PQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQSNSGATKRASPSNSRR 1331
Cdd:pfam05109 565 PtPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSSTSSM 644
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 970841901 1332 SSPGSSRKTTPSPGRQN---SKAPKLTLASQTNAALLQNVELPRNVLVSPTPLANPPVPGSFPNNSGlnPQNST 1402
Cdd:pfam05109 645 SLRPSSISETLSPSTSDnstSHMPLLTSAHPTGGENITQVTPASTSTHHVSTSSPAPRPGTTSQASG--PGNSS 716
|
|
| SOBP |
pfam15279 |
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual ... |
1080-1294 |
2.90e-03 |
|
Sine oculis-binding protein; SOBP is associated with syndromic and nonsyndromic intellectual disability. It carries a zinc-finger of the zf-C2H2 type at the N-terminus, and a highly characteriztic C-terminal PhPhPhPhPhPh motif. The deduced 873-amino acid protein contains an N-terminal nuclear localization signal (NLS), followed by 2 FCS-type zinc finger motifs, a proline-rich region (PR1), a putative RNA-binding motif region, and a C-terminal NLS embedded in a second proline-rich motif. SOBP is expressed in various human tissues, including developing mouse brain at embryonic day 14. In postnatal and adult mouse brain SOBP is expressed in all neurons, with intense staining in the limbic system. Highest expression is in layer V cortical neurons, hippocampus, pyriform cortex, dorsomedial nucleus of thalamus, amygdala, and hypothalamus. Postnatal expression of SOBP in the limbic system corresponds to a time of active synaptogenesis. the family is also referred to as Jackson circler, JXC1. In seven affected siblings from a consanguineous Israeli Arab family with mental retardation, anterior maxillary protrusion, and strabismus mutations were found in this protein.
Pssm-ID: 464609 [Multi-domain] Cd Length: 325 Bit Score: 42.11 E-value: 2.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1080 VSLQGPASVPPSPDKQRMPMPVNTPLGS--NSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLP 1157
Cdd:pfam15279 91 ESVSPGPSSSASPSSSPTSSNSSKPLISvaSSSKLLAPKPHEPPSLPPPPLPPKKGRRHRPGLHPPLGRPPGSPPMSMTP 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 970841901 1158 QNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHhfPNVAAPTQTSRPKTPNRASPRPYYPQT-PNNRPP-----S 1231
Cdd:pfam15279 171 RGLLGKPQQHPPPSPLPAFMEPSSMPPPFLRPPPSIPQ--PNSPLSNPMLPGIGPPPKPPRNLGPPSnPMHRPPfsphhP 248
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 970841901 1232 TEPSEISLSPERLNASIAGLFPPQINIPLPPrpnLNRGFDQQGLNPTTLKAIGQAPSNLTMNP 1294
Cdd:pfam15279 249 PPPPTPPGPPPGLPPPPPRGFTPPFGPPFPP---VNMMPNPPEMNFGLPSLAPLVPPVTVLVP 308
|
|
| |
