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Conserved domains on  [gi|968121863|ref|NP_001304989|]
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protein DBF4 homolog A isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ZnF_DBF super family cl46924
Zinc finger in DBF-like proteins;
61-103 2.43e-15

Zinc finger in DBF-like proteins;


The actual alignment was detected with superfamily member smart00586:

Pssm-ID: 128854 [Multi-domain]  Cd Length: 49  Bit Score: 69.81  E-value: 2.43e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 968121863    61 GYCECCLQKYEDLETHLLSEQHRNFAQSN-QYQVVDDIVSKLVF 103
Cdd:smart00586   6 GYCENCREKYDDLETHLLSEKHRRFAENNdNFQALDDLISQLRR 49
 
Name Accession Description Interval E-value
ZnF_DBF smart00586
Zinc finger in DBF-like proteins;
61-103 2.43e-15

Zinc finger in DBF-like proteins;


Pssm-ID: 128854 [Multi-domain]  Cd Length: 49  Bit Score: 69.81  E-value: 2.43e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 968121863    61 GYCECCLQKYEDLETHLLSEQHRNFAQSN-QYQVVDDIVSKLVF 103
Cdd:smart00586   6 GYCENCREKYDDLETHLLSEKHRRFAENNdNFQALDDLISQLRR 49
zf-DBF pfam07535
DBF zinc finger; This domain is predicted to bind metal ions and is often found associated ...
 61-101 2.71e-14

DBF zinc finger; This domain is predicted to bind metal ions and is often found associated with pfam00533 and pfam02178. It was first identified in the Drosophila chiffon gene product, and is associated with initiation of DNA replication.


Pssm-ID: 462197  Cd Length: 42  Bit Score: 66.75  E-value: 2.71e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 968121863   61 GYCECCLQKYEDLETHLLSEQHRNFAQ-SNQYQVVDDIVSKL 101
Cdd:pfam07535   1 GYCENCRVKYEDLEEHIVSEKHRKFAEnDSNFKELDELISKL 42
DBF4 COG5067
Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, ...
 61-103 4.65e-06

Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, and repair / Cell division and chromosome partitioning];


Pssm-ID: 227399 [Multi-domain]  Cd Length: 468  Bit Score: 48.79  E-value: 4.65e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 968121863  61 GYCECCLQKYEDLETHLLSEQHRNFAQSNQ-YQVVDDIVSKLVF 103
Cdd:COG5067  423 GYCENCREKYESLEQHIVSEKHRRFAENDLnFEALDSLFELLRR 466
 
Name Accession Description Interval E-value
ZnF_DBF smart00586
Zinc finger in DBF-like proteins;
61-103 2.43e-15

Zinc finger in DBF-like proteins;


Pssm-ID: 128854 [Multi-domain]  Cd Length: 49  Bit Score: 69.81  E-value: 2.43e-15
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....
gi 968121863    61 GYCECCLQKYEDLETHLLSEQHRNFAQSN-QYQVVDDIVSKLVF 103
Cdd:smart00586   6 GYCENCREKYDDLETHLLSEKHRRFAENNdNFQALDDLISQLRR 49
zf-DBF pfam07535
DBF zinc finger; This domain is predicted to bind metal ions and is often found associated ...
 61-101 2.71e-14

DBF zinc finger; This domain is predicted to bind metal ions and is often found associated with pfam00533 and pfam02178. It was first identified in the Drosophila chiffon gene product, and is associated with initiation of DNA replication.


Pssm-ID: 462197  Cd Length: 42  Bit Score: 66.75  E-value: 2.71e-14
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 968121863   61 GYCECCLQKYEDLETHLLSEQHRNFAQ-SNQYQVVDDIVSKL 101
Cdd:pfam07535   1 GYCENCRVKYEDLEEHIVSEKHRKFAEnDSNFKELDELISKL 42
DBF4 COG5067
Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, ...
 61-103 4.65e-06

Protein kinase essential for the initiation of DNA replication [DNA replication, recombination, and repair / Cell division and chromosome partitioning];


Pssm-ID: 227399 [Multi-domain]  Cd Length: 468  Bit Score: 48.79  E-value: 4.65e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 968121863  61 GYCECCLQKYEDLETHLLSEQHRNFAQSNQ-YQVVDDIVSKLVF 103
Cdd:COG5067  423 GYCENCREKYESLEQHIVSEKHRRFAENDLnFEALDSLFELLRR 466
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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