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Conserved domains on  [gi|961525467|ref|NP_001304826|]
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small integral membrane protein 14 [Homo sapiens]

Protein Classification

SMIM14 family protein( domain architecture ID 10567257)

SMIM14 family protein is a DUF2615 domain-containing protein; similar to Homo sapiens small integral membrane protein 14, a novel endoplasmic reticulum resident protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF2615 pfam11027
Protein of unknown function (DUF2615); This small. approximately 100 residue, family is ...
 3-97 2.54e-48

Protein of unknown function (DUF2615); This small. approximately 100 residue, family is conserved from worms to humans. It is cysteine-rich with a characteriztic FDxCEC sequence motif. The function is not known.


:

Pssm-ID: 402563  Cd Length: 102  Bit Score: 149.01  E-value: 2.54e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961525467    3 EGGFDPCECVCSHEHAMRRLINLLRQSQSYCTDTECLQELPGPSGDN--GISVTMILVAWMVIALILFLLRPPNLRGSSL 80
Cdd:pfam11027   1 EDGFDPCECIWSHELAMRRLLSLLRQSQSYCTDNECLDDLPGPQGSGngGNSGFFIAFLWLVVAMVLYLLRPSSLRNSSD 80

                          90       100
                  ....*....|....*....|..
gi 961525467   81 PGKPTSPHNGQD-----PPAPP 97
Cdd:pfam11027  81 DNKPSRRDNNDDgdnppPPPPP 102
 
Name Accession Description Interval E-value
DUF2615 pfam11027
Protein of unknown function (DUF2615); This small. approximately 100 residue, family is ...
 3-97 2.54e-48

Protein of unknown function (DUF2615); This small. approximately 100 residue, family is conserved from worms to humans. It is cysteine-rich with a characteriztic FDxCEC sequence motif. The function is not known.


Pssm-ID: 402563  Cd Length: 102  Bit Score: 149.01  E-value: 2.54e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961525467    3 EGGFDPCECVCSHEHAMRRLINLLRQSQSYCTDTECLQELPGPSGDN--GISVTMILVAWMVIALILFLLRPPNLRGSSL 80
Cdd:pfam11027   1 EDGFDPCECIWSHELAMRRLLSLLRQSQSYCTDNECLDDLPGPQGSGngGNSGFFIAFLWLVVAMVLYLLRPSSLRNSSD 80

                          90       100
                  ....*....|....*....|..
gi 961525467   81 PGKPTSPHNGQD-----PPAPP 97
Cdd:pfam11027  81 DNKPSRRDNNDDgdnppPPPPP 102
 
Name Accession Description Interval E-value
DUF2615 pfam11027
Protein of unknown function (DUF2615); This small. approximately 100 residue, family is ...
 3-97 2.54e-48

Protein of unknown function (DUF2615); This small. approximately 100 residue, family is conserved from worms to humans. It is cysteine-rich with a characteriztic FDxCEC sequence motif. The function is not known.


Pssm-ID: 402563  Cd Length: 102  Bit Score: 149.01  E-value: 2.54e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 961525467    3 EGGFDPCECVCSHEHAMRRLINLLRQSQSYCTDTECLQELPGPSGDN--GISVTMILVAWMVIALILFLLRPPNLRGSSL 80
Cdd:pfam11027   1 EDGFDPCECIWSHELAMRRLLSLLRQSQSYCTDNECLDDLPGPQGSGngGNSGFFIAFLWLVVAMVLYLLRPSSLRNSSD 80

                          90       100
                  ....*....|....*....|..
gi 961525467   81 PGKPTSPHNGQD-----PPAPP 97
Cdd:pfam11027  81 DNKPSRRDNNDDgdnppPPPPP 102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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