|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
73-278 |
6.27e-107 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 320.67 E-value: 6.27e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 73 FSKVCVNEEGIQKLQRAIQE-HPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMkMVGELLRMSGAFFMRRT 151
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEgHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIP-ILGTLLRRLGAFFIRRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 152 FGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETL 231
Cdd:cd07993 80 FGKDPLYRAVLQEYVQELLKNGQ-PLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEEL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 939106619 232 YVYELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDPVSLRSLAA 278
Cdd:cd07993 159 YAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
33-583 |
9.85e-102 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 324.57 E-value: 9.85e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 33 QSVDVLREEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVNeeGIQKLQRAIQEHPVVLLPSHRSYIDFLMLSF 112
Cdd:COG2937 145 ISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD--NLERLRELAKGHEIVYVPCHRSHMDYLLLSY 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 113 LLYNYDLPVPVIAAG--MDFLGmkmVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAK 190
Cdd:COG2937 223 VLYHNGLVPPHIAAGinLNFWP---LGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERGY-SVEYFIEGGRSRTGR 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 191 TLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDP 270
Cdd:COG2937 299 LLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRALRKLRRRFGRVYVNFGEP 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 271 VSLRSLAAgrmsrsSYNLVPRYIPQKQSEDMHAFVTEVAYK-MEllQIEN-MVLSPWTLIVAVLLQNRP-SMDFDALVEK 347
Cdd:COG2937 379 ISLSEYLD------QHVPDWRESEDLRPEWLRPAVDKLAFEiMV--RINRaAAVNPVNLVALALLASPKrALTEAELLAQ 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 348 TLWLKGLTQAFGGfliwPDNKPAEEVVPASILLHsniasLVKDQVILKVDSGDSEVVdglML---QHITLlmcSAYRNQL 424
Cdd:COG2937 451 LDLYLDLLRNVPY----SLSVTLPELTPEELLEH-----LLSLGLIEVEKDGLGDVI---SIddeQAVLL---TYYRNNI 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 425 LNIFVRPSLVAVALQMTPGFRKEDVYSCFRFLRDVFADEFIFLPGNTLKD-FEEGCYLLCKSEAIQVTTKDILVTEKGNT 503
Cdd:COG2937 516 LHLFALPALIASALLANRRISRAELLELVRLLYPLLKAELFLRWDAEFEEvLDEELDELVRQGLLEREGDTLRRPPARFR 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 504 VLEFLVGLFKPFVESYQIICKYLLSEEEDHFSEEQYLAAVRKFTSQLLDQGTSQCYDVLSSDVQKNALAACVRLGVVEKK 583
Cdd:COG2937 596 QLQLLAHVLRETLERYAIVLSLLAKLGSGTLDRKELEKESLLLAQRLSLLHGINAPEFFDKALFRNFIQTLREQGYLDDD 675
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
18-547 |
6.11e-74 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 256.73 E-value: 6.11e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 18 PSAVVLLYSLS-KESLQSVDVLREEVSeILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVNEEGIQKLQRAIQEhP-- 94
Cdd:PTZ00374 552 PSIQRLMTALAkKEGASEKDVEARAKA-ILRTCGDNLNHVQCRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAM-Prv 629
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 95 -VVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRnG 173
Cdd:PTZ00374 630 aVVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDDFLRMGPIATLMRGSGAFFMRRSFRDDPLYAALFKEYVRHLVL-R 708
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 174 YAPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFF--KREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLK 251
Cdd:PTZ00374 709 RRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYegQQELDDVLIIPVSLSYDELLETTLYAKEQLGVSKPKENPGNLLR 788
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 252 ARKILSENFGSIHVYFGDPVSLRSLA-------------AGRMSRSSYNL--------VPRYIPQKqsedmhaFVTEVAY 310
Cdd:PTZ00374 789 ARSLLKRRHGKIHVHIGEPVSLRSFKdhplqcplpfepkGEATTSVCKTLdttpsiarKSSITPPR-------VLTNIAW 861
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 311 K-MELLQiENMVLSPWTLIVAVLLQNRPS---MDFDALVEKTLWLKGLTQAFGGFL-IWPDNKPAEEVVPASIllhSNIA 385
Cdd:PTZ00374 862 HlTHKLQ-RNTIITPTALVAAVLECLGPTagaMPLAEVQQGMTWLRTNIRRRGAALsDDCANLNPETMVRKAL---THLQ 937
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 386 SLVKdqvILKVDSGDSEVVDGLMlQHITLLMCSayrNQLLNIFVRPSLVAVALQM-----TPGFR---KEDVYS--CfRF 455
Cdd:PTZ00374 938 EFVE---ITDEMSEVIYVRQDVV-TRLGVNICS---NQLIHVFMDEAVVAVVARAfgevtAPHRVrrvEADVLKeqC-QL 1009
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 456 LRDVFADEFiflpgntlKDFEEGC------YLLCKSEAIQVTTKDIL-VTEKGNTVLEFLVGLFKPFVESYQIICKYLLS 528
Cdd:PTZ00374 1010 LRQLLSAEF--------QDYLPACpytfasWHGLELKPVAKEAAYTIpATADRTVLLERLQQLMRHVCEMRSSSPHLLRA 1081
|
570 580
....*....|....*....|..
gi 939106619 529 EEEDHFSE---EQYLAAVRKFT 547
Cdd:PTZ00374 1082 EEQKKAREdilKEYVKVLRRMK 1103
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
39-435 |
4.72e-58 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 208.93 E-value: 4.72e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 39 REEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCV-NEEGIQKLqrAIQEHPVVLLPSHRSYIDFLMLSFLLYNY 117
Cdd:PRK04974 249 RQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVhNAERVRQL--AQDGHEIVYVPCHRSHMDYLLLSYVLYHQ 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 118 DLPVPVIAAGMDfLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFG 197
Cdd:PRK04974 327 GLVPPHIAAGIN-LNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFARGY-SVEYFVEGGRSRTGRLLQPKTG 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 198 LLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSeNFGSIHVYFGDPVSLRSLA 277
Cdd:PRK04974 405 MLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRGIRKLR-NFGQGYVNFGEPIPLNDYL 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 278 AGRM--SRSSYNLVPRYIPQKqsedMHAFVTEVAYKMeLLQIEN-MVLSPWTLIVAVLLQNRP-SMDFDALVEK-TLWLK 352
Cdd:PRK04974 484 NQHVpeWRESIDPIEEQRPAW----LTPAVNNLANQV-MVRINNaAAANPVNLCALALLASRQrALDREQLIEQlDLYLQ 558
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 353 GLTQA-FGGFLIWPDNKPAEevvpasILLHS---NIASLVKDQV--ILKVDsgDSEVVdgLMlqhitllmcSAYRNQLLN 426
Cdd:PRK04974 559 LLRNVpYSSDTTVPEGSGEE------LIDHAlslNKFEVEKDTLgdIISLD--REQAV--LM---------TYYRNNILH 619
|
....*....
gi 939106619 427 IFVRPSLVA 435
Cdd:PRK04974 620 LFVLPSLIA 628
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
77-222 |
1.08e-30 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 116.61 E-value: 1.08e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 77 CVNEEGIQKLQRaiqEHPVVLLPSHRSYIDFLMLSFLLYNYDLPvPVIAAGMDFLGMKMVGELLRMSGAFFMRRtfgGNK 156
Cdd:pfam01553 1 RIEVHGLENLPR---GGPAIVVANHQSYLDVLLLSLALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDR---KNR 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 939106619 157 LYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISIS 222
Cdd:pfam01553 74 KDAAGTLEYLVELLREGK-LVVIFPEGTRSREGELLPFKKGAFRLAIE-------AGVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
95-224 |
1.53e-22 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 93.19 E-value: 1.53e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 95 VVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLgMKMVGELLRMSGAFFMRRTFGgnKLYWAVFSEYVKtMLRNGY 174
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFY-VPLLGWLLRLLGAIFIDRSNG--RKARAALREAVE-LLKEGE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 939106619 175 aPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPffkrevfDTYLVPISISYD 224
Cdd:smart00563 77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
232-521 |
7.72e-17 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 82.57 E-value: 7.72e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 232 YVYELLGVPKPKESTTGLLK-ARKILSENFGSIHVYFGDPVSLRSLAAGRMSRSSYnlvpryipqkQSEDMHAFVTEVAY 310
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSyARSQLSLKLGRVYVRFGEPWSLREFLDEQGDRPAT----------DAARRRLALQKLAF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 311 KMeLLQI-ENMVLSPWTLIVAVLLQNRP-SMDFDALVEKTLWL------KGLTQAFGGFLiwpdnkPAEEVVPASillhs 382
Cdd:pfam19277 71 EV-LSRInRVTPVMPTALVGTVLLTLRGrALTLSELIRRVEWLldyiraRGGPVAHFGDL------RTEEVVDRA----- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 383 nIASLVKDQVILKVDSGDSEV-----VDGLMLqhitllmcSAYRNQLLNIFVRPSLVAVALQMTP-----GFRKEDVYSC 452
Cdd:pfam19277 139 -LDVLGNAGLVTRVDGGPEPVyyiapEDHFQA--------SFYRNMTIHLFVERAIVELALLTKVkaaqrGDSYEALWDQ 209
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 453 FRFLRDVFADEFIFLPGNTLK-DFEEGCYLLCKSEAIQVTTKDILVTEKGNTVLEFLVGLFKPFVESYQI 521
Cdd:pfam19277 210 VLRLRDLLKFEFFFPPKEGFReNLRAELDLLDPWEDRVITGERDIERLLGRENPDFACFLLWPFIEAYWL 279
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
91-277 |
3.89e-10 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 60.02 E-value: 3.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 91 QEHPVVLLPSHRSYIDFLMLSFLlynydLPVPV-IAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNKLywAVFsEYVKTM 169
Cdd:COG0204 41 ADGPVLIVANHQSWLDILLLLAA-----LPRPVrFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAAL--RAL-RQAVEA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 170 LRNGYAPVeFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISISYdkileeTLYVYELLGVPKPkesttgl 249
Cdd:COG0204 113 LKAGESLV-IFPEGTRSPDGRLLPFKTGAARLALE-------AGVPIVPVAIDG------TERALPKGFLPRP------- 171
|
170 180
....*....|....*....|....*...
gi 939106619 250 lkarkilsenfGSIHVYFGDPVSLRSLA 277
Cdd:COG0204 172 -----------GKVTVRIGPPIDPSDLE 188
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
73-278 |
6.27e-107 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 320.67 E-value: 6.27e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 73 FSKVCVNEEGIQKLQRAIQE-HPVVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMkMVGELLRMSGAFFMRRT 151
Cdd:cd07993 1 FDGVQVNEGQLERLRKAAQEgHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIP-ILGTLLRRLGAFFIRRS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 152 FGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETL 231
Cdd:cd07993 80 FGKDPLYRAVLQEYVQELLKNGQ-PLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEEL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 939106619 232 YVYELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDPVSLRSLAA 278
Cdd:cd07993 159 YAEELLGPPKPKESLSGLLGASKILRENFGRIRVDFGEPISLREYLG 205
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
33-583 |
9.85e-102 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 324.57 E-value: 9.85e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 33 QSVDVLREEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVNeeGIQKLQRAIQEHPVVLLPSHRSYIDFLMLSF 112
Cdd:COG2937 145 ISEEKARKEARRYLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVD--NLERLRELAKGHEIVYVPCHRSHMDYLLLSY 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 113 LLYNYDLPVPVIAAG--MDFLGmkmVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAK 190
Cdd:COG2937 223 VLYHNGLVPPHIAAGinLNFWP---LGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERGY-SVEYFIEGGRSRTGR 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 191 TLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSENFGSIHVYFGDP 270
Cdd:COG2937 299 LLPPKTGMLSMTVQAFLRGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRALRKLRRRFGRVYVNFGEP 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 271 VSLRSLAAgrmsrsSYNLVPRYIPQKQSEDMHAFVTEVAYK-MEllQIEN-MVLSPWTLIVAVLLQNRP-SMDFDALVEK 347
Cdd:COG2937 379 ISLSEYLD------QHVPDWRESEDLRPEWLRPAVDKLAFEiMV--RINRaAAVNPVNLVALALLASPKrALTEAELLAQ 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 348 TLWLKGLTQAFGGfliwPDNKPAEEVVPASILLHsniasLVKDQVILKVDSGDSEVVdglML---QHITLlmcSAYRNQL 424
Cdd:COG2937 451 LDLYLDLLRNVPY----SLSVTLPELTPEELLEH-----LLSLGLIEVEKDGLGDVI---SIddeQAVLL---TYYRNNI 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 425 LNIFVRPSLVAVALQMTPGFRKEDVYSCFRFLRDVFADEFIFLPGNTLKD-FEEGCYLLCKSEAIQVTTKDILVTEKGNT 503
Cdd:COG2937 516 LHLFALPALIASALLANRRISRAELLELVRLLYPLLKAELFLRWDAEFEEvLDEELDELVRQGLLEREGDTLRRPPARFR 595
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 504 VLEFLVGLFKPFVESYQIICKYLLSEEEDHFSEEQYLAAVRKFTSQLLDQGTSQCYDVLSSDVQKNALAACVRLGVVEKK 583
Cdd:COG2937 596 QLQLLAHVLRETLERYAIVLSLLAKLGSGTLDRKELEKESLLLAQRLSLLHGINAPEFFDKALFRNFIQTLREQGYLDDD 675
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
18-547 |
6.11e-74 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 256.73 E-value: 6.11e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 18 PSAVVLLYSLS-KESLQSVDVLREEVSeILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCVNEEGIQKLQRAIQEhP-- 94
Cdd:PTZ00374 552 PSIQRLMTALAkKEGASEKDVEARAKA-ILRTCGDNLNHVQCRLFGLMVRRILFRLYDRVSLNSGAFERLHRYVAM-Prv 629
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 95 -VVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRnG 173
Cdd:PTZ00374 630 aVVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDDFLRMGPIATLMRGSGAFFMRRSFRDDPLYAALFKEYVRHLVL-R 708
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 174 YAPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPFF--KREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLK 251
Cdd:PTZ00374 709 RRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYegQQELDDVLIIPVSLSYDELLETTLYAKEQLGVSKPKENPGNLLR 788
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 252 ARKILSENFGSIHVYFGDPVSLRSLA-------------AGRMSRSSYNL--------VPRYIPQKqsedmhaFVTEVAY 310
Cdd:PTZ00374 789 ARSLLKRRHGKIHVHIGEPVSLRSFKdhplqcplpfepkGEATTSVCKTLdttpsiarKSSITPPR-------VLTNIAW 861
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 311 K-MELLQiENMVLSPWTLIVAVLLQNRPS---MDFDALVEKTLWLKGLTQAFGGFL-IWPDNKPAEEVVPASIllhSNIA 385
Cdd:PTZ00374 862 HlTHKLQ-RNTIITPTALVAAVLECLGPTagaMPLAEVQQGMTWLRTNIRRRGAALsDDCANLNPETMVRKAL---THLQ 937
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 386 SLVKdqvILKVDSGDSEVVDGLMlQHITLLMCSayrNQLLNIFVRPSLVAVALQM-----TPGFR---KEDVYS--CfRF 455
Cdd:PTZ00374 938 EFVE---ITDEMSEVIYVRQDVV-TRLGVNICS---NQLIHVFMDEAVVAVVARAfgevtAPHRVrrvEADVLKeqC-QL 1009
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 456 LRDVFADEFiflpgntlKDFEEGC------YLLCKSEAIQVTTKDIL-VTEKGNTVLEFLVGLFKPFVESYQIICKYLLS 528
Cdd:PTZ00374 1010 LRQLLSAEF--------QDYLPACpytfasWHGLELKPVAKEAAYTIpATADRTVLLERLQQLMRHVCEMRSSSPHLLRA 1081
|
570 580
....*....|....*....|..
gi 939106619 529 EEEDHFSE---EQYLAAVRKFT 547
Cdd:PTZ00374 1082 EEQKKAREdilKEYVKVLRRMK 1103
|
|
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
39-435 |
4.72e-58 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 208.93 E-value: 4.72e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 39 REEVSEILDEMSHKLRLGAIRFCAFTLSKVFKQIFSKVCV-NEEGIQKLqrAIQEHPVVLLPSHRSYIDFLMLSFLLYNY 117
Cdd:PRK04974 249 RQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVhNAERVRQL--AQDGHEIVYVPCHRSHMDYLLLSYVLYHQ 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 118 DLPVPVIAAGMDfLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFG 197
Cdd:PRK04974 327 GLVPPHIAAGIN-LNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFARGY-SVEYFVEGGRSRTGRLLQPKTG 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 198 LLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSeNFGSIHVYFGDPVSLRSLA 277
Cdd:PRK04974 405 MLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRGIRKLR-NFGQGYVNFGEPIPLNDYL 483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 278 AGRM--SRSSYNLVPRYIPQKqsedMHAFVTEVAYKMeLLQIEN-MVLSPWTLIVAVLLQNRP-SMDFDALVEK-TLWLK 352
Cdd:PRK04974 484 NQHVpeWRESIDPIEEQRPAW----LTPAVNNLANQV-MVRINNaAAANPVNLCALALLASRQrALDREQLIEQlDLYLQ 558
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 353 GLTQA-FGGFLIWPDNKPAEevvpasILLHS---NIASLVKDQV--ILKVDsgDSEVVdgLMlqhitllmcSAYRNQLLN 426
Cdd:PRK04974 559 LLRNVpYSSDTTVPEGSGEE------LIDHAlslNKFEVEKDTLgdIISLD--REQAV--LM---------TYYRNNILH 619
|
....*....
gi 939106619 427 IFVRPSLVA 435
Cdd:PRK04974 620 LFVLPSLIA 628
|
|
| PRK03355 |
PRK03355 |
glycerol-3-phosphate 1-O-acyltransferase; |
27-581 |
9.65e-46 |
|
glycerol-3-phosphate 1-O-acyltransferase;
Pssm-ID: 179567 [Multi-domain] Cd Length: 783 Bit Score: 173.36 E-value: 9.65e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 27 LSKESLQSVDVLREEVSEILDEMShklrLGAIRFcAFTLSKVFKQIFS-----KVCVNEEGIQKLQRAIQEHPVVLLPSH 101
Cdd:PRK03355 201 IAAKLGRPPGATVREAGKMLDELV----AGWSRV-SVDLVSVLGRLFSrgfdpEIDYDEYELAALRALLEEHPAVLLFSH 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 102 RSYIDFLMLSFLLYNYDLPVPVIAAGMDfLGMKMVGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNGYaPVEFFL 181
Cdd:PRK03355 276 RSYIDGLVVPVAMQENRLPPVHVFGGIN-LSFGPMGPIMRRSGMIFIRRNIGDDPLYKYVLREYVGYLVEKRF-NLSWYI 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 182 EGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSE-NF 260
Cdd:PRK03355 354 EGTRSRTGKLLPPKLGLLSYVADAYLDGRSDDVLLQPVSISFDQLHEIGEYAAEARGGEKTPEGLRWLYNYIKAQGErNY 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 261 GSIHVYFGDPVSLRS-LAAGRMSRSSYNLVPRYIPQKQsedmhAFvtEVAYkmELLQIENMVLSpwTLIVAVLLQNRPsm 339
Cdd:PRK03355 434 GKIYVRFGEPVSMRQyLGAPHGPLTQDPDAKRLALQKM-----AF--EVAW--RINQVTPVTAT--SLVSLLLLGTRG-- 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 340 dfdalveKTLWLKGLTQAFGGFLIW------PDNKPA-----EEVVPASILLHSNiaslvkDQVILKVDSGDSEVVDGLM 408
Cdd:PRK03355 501 -------RALTLDELHHTLQDSLDYlerrqlPVSTSAlrlrdPEGVRAALDALSN------GGPVTRVDSGREPVWYIAP 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 409 LQHitlLMCSAYRNQLLNIFVRPSLVAVALQMTPGFRKEDVYSCF-----RfLRDVFADEFIFLPGNTLK---------- 473
Cdd:PRK03355 568 DDH---LVAAFYRNSVIHAFLERAIVELALAAAAHVDEGDRLAAFwdqamR-LRDLLKFEFFFADSDAFRanlraemawi 643
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 474 --DFEEgcyllckSEAIQVTTKDILVTEKGntvleFLVG--LFKPFVESYQIICKYLLSEEEDHFSEEQYLAAVRKFTSQ 549
Cdd:PRK03355 644 dpDWED-------RLAAGGDEIDALLRAKR-----PLMAhaMLRPFFEAYEVVADVLRDAPPDTIDEKELTALALGLGRQ 711
|
570 580 590
....*....|....*....|....*....|..
gi 939106619 550 LLDQGTSQCYDVLSSDVQKNALAACVRLGVVE 581
Cdd:PRK03355 712 YVLQGRVRSSESVSTLLFATARQLARDQGLLE 743
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
77-222 |
1.08e-30 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 116.61 E-value: 1.08e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 77 CVNEEGIQKLQRaiqEHPVVLLPSHRSYIDFLMLSFLLYNYDLPvPVIAAGMDFLGMKMVGELLRMSGAFFMRRtfgGNK 156
Cdd:pfam01553 1 RIEVHGLENLPR---GGPAIVVANHQSYLDVLLLSLALYKRGRP-LVFVAKKELFDIPLVGWLMRLLGCIFIDR---KNR 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 939106619 157 LYWAVFSEYVKTMLRNGYaPVEFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISIS 222
Cdd:pfam01553 74 KDAAGTLEYLVELLREGK-LVVIFPEGTRSREGELLPFKKGAFRLAIE-------AGVPIVPVAIS 131
|
|
| LPLAT |
cd06551 |
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
73-279 |
3.91e-26 |
|
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).
Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 105.57 E-value: 3.91e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 73 FSKVCVNEEGIQKLQRAIQEH-----PVVLLPSHRSYIDFLMLSFLLYNYdLPVPVIAAGMDFLGMKmvGELLRMSGAFF 147
Cdd:cd06551 1 FRYLLLNFFGFVRLEVKGPPPppgggPVLFVSNHSSWWDGLILFLLLERG-LRRDVYGLMDEELLER--YPFFTRLGAFS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 148 MRRTFGGnklYWAVFSEYVKTMLRNGYAPVEFFLEGTRSR-SAKTLTPKFGLLNIvmepffkREVFDTYLVPISISYDKI 226
Cdd:cd06551 78 VDRDSPR---SAAKSLKYVARLLSKPGSVVWIFPEGTRTRrDKRPLQFKPGVAHL-------AEKAGVPIVPVALRYTFE 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 939106619 227 LEetlyvyellgvpkpkesttgllkarkilsENFGSIHVYFGDPVSLRSLAAG 279
Cdd:cd06551 148 LF-----------------------------EQFPEIFVRIGPPIPYAETALG 171
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
95-224 |
1.53e-22 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 93.19 E-value: 1.53e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 95 VVLLPSHRSYIDFLMLSFLLYNYDLPVPVIAAGMDFLgMKMVGELLRMSGAFFMRRTFGgnKLYWAVFSEYVKtMLRNGY 174
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFY-VPLLGWLLRLLGAIFIDRSNG--RKARAALREAVE-LLKEGE 76
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 939106619 175 aPVEFFLEGTRSRSAKTLTPKFGLLNIVMEPffkrevfDTYLVPISISYD 224
Cdd:smart00563 77 -WLLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRGT 118
|
|
| PRK11915 |
PRK11915 |
lysophospholipid acyltransferase; |
24-541 |
6.93e-21 |
|
lysophospholipid acyltransferase;
Pssm-ID: 237022 [Multi-domain] Cd Length: 621 Bit Score: 96.94 E-value: 6.93e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 24 LYSLSKESLQSVDVLREEVSEILDEMSHKLRLGAIR-FCAFtlSKVFKQIFSkVCVNEEGIQKLQRAIQEHPVVLLPSHR 102
Cdd:PRK11915 48 LRALADELGRDPDSVRAEAAGYLREMAASLDERAVQaWRGF--SRWLMRAYD-VLVDEDQITQLRKLDRKATLAFAFSHR 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 103 SYID-FLMLSFLLYNYDLPVPVIA-AGMDFLGMkmvGELLRMSGAFFMRRTFGGNKLYWAVFSEYVKTMLRNgYAPVEFF 180
Cdd:PRK11915 125 SYLDgMLLPEVILANRLSPALTFGgANLNFFPM---GAWAKRTGAIFIRRQTKDIPVYRFVLRAYAAQLVQN-HVNLTWS 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 181 LEGTRSRSAKTLTPKFGLLNIVMEPFFKREVFDTYLVPISISYDKILEETLYVYELLGVPKPKESTTGLLKARKILSENF 260
Cdd:PRK11915 201 IEGGRTRTGKLRPPVFGILRYITDAVDEIDGPEVYLVPTSIVYDQLHEVEAMTTEAYGAVKRPEDLRFLVRLARQQGERL 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 261 GSIHVYFGDPVSLRS-LAAGRMSRSSynlvpryipqKQSEdmhafVTEVAYKMELLQIENMVLSPWTLIVAVLLQNRPSM 339
Cdd:PRK11915 281 GRAYLDFGEPLPLRKrLQELRADKSG----------TGSE-----IERIALDVEHRINRATPVTPTAVVSLALLGADRSL 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 340 DFDALVEKTLWLKGLTQAFGgfliWPDNKPAEEVVPASI--LLHSNIASlvkdQVILKVDSGdSEVVDGLML-QHitlLM 416
Cdd:PRK11915 346 SISEVLATVRPLASYIAARN----WAVAGAADLTNRSTIrwTLHQMVAS----GVVSVYDAG-TEAVWGIGEdQH---LV 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 417 CSAYRNQLLNIFVRPSLVAVALQMTPGFRKE------DVYSCFRFLRDVFADEFIFlPGNTL--KDFEEGCYLLCKSEAI 488
Cdd:PRK11915 414 AAFYRNTAIHILVDRAIAELALLAAAETTTNgsvspaTVRDEALSLRELLKFEFLF-SGRAQfeKDLANEVRLIGSVVDT 492
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 939106619 489 Q--VTTKDIL-VTEKGNTVLEFLVglFKPFVESYQIICKYLLSEEEDHFSEEQYLA 541
Cdd:PRK11915 493 SkaAAAADVWrLLESADLLLAHLV--LRPFLDAYHIVADRLAAHEDDSFDEEGFLA 546
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
232-521 |
7.72e-17 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 82.57 E-value: 7.72e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 232 YVYELLGVPKPKESTTGLLK-ARKILSENFGSIHVYFGDPVSLRSLAAGRMSRSSYnlvpryipqkQSEDMHAFVTEVAY 310
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSyARSQLSLKLGRVYVRFGEPWSLREFLDEQGDRPAT----------DAARRRLALQKLAF 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 311 KMeLLQI-ENMVLSPWTLIVAVLLQNRP-SMDFDALVEKTLWL------KGLTQAFGGFLiwpdnkPAEEVVPASillhs 382
Cdd:pfam19277 71 EV-LSRInRVTPVMPTALVGTVLLTLRGrALTLSELIRRVEWLldyiraRGGPVAHFGDL------RTEEVVDRA----- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 383 nIASLVKDQVILKVDSGDSEV-----VDGLMLqhitllmcSAYRNQLLNIFVRPSLVAVALQMTP-----GFRKEDVYSC 452
Cdd:pfam19277 139 -LDVLGNAGLVTRVDGGPEPVyyiapEDHFQA--------SFYRNMTIHLFVERAIVELALLTKVkaaqrGDSYEALWDQ 209
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 453 FRFLRDVFADEFIFLPGNTLK-DFEEGCYLLCKSEAIQVTTKDILVTEKGNTVLEFLVGLFKPFVESYQI 521
Cdd:pfam19277 210 VLRLRDLLKFEFFFPPKEGFReNLRAELDLLDPWEDRVITGERDIERLLGRENPDFACFLLWPFIEAYWL 279
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
91-277 |
3.89e-10 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 60.02 E-value: 3.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 91 QEHPVVLLPSHRSYIDFLMLSFLlynydLPVPV-IAAGMDFLGMKMVGELLRMSGAFFMRRTFGGNKLywAVFsEYVKTM 169
Cdd:COG0204 41 ADGPVLIVANHQSWLDILLLLAA-----LPRPVrFVAKKELFKIPLLGWLLRALGAIPVDRSKRRAAL--RAL-RQAVEA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 170 LRNGYAPVeFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISISYdkileeTLYVYELLGVPKPkesttgl 249
Cdd:COG0204 113 LKAGESLV-IFPEGTRSPDGRLLPFKTGAARLALE-------AGVPIVPVAIDG------TERALPKGFLPRP------- 171
|
170 180
....*....|....*....|....*...
gi 939106619 250 lkarkilsenfGSIHVYFGDPVSLRSLA 277
Cdd:COG0204 172 -----------GKVTVRIGPPIDPSDLE 188
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
94-283 |
3.98e-10 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 59.21 E-value: 3.98e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 94 PVVLLPSHRSYIDFLMLSFLLYNYdlPVPVIAAgmDFLGMKMVGELLRMSGAFFMRRtfGGNKLYWAVFsEYVKTMLRNG 173
Cdd:cd07989 25 PVIIVANHQSYLDPLVLGAALPRP--IRFVAKK--ELFKIPFLGWLLRLLGAIPIDR--GNGRSAREAL-REAIEALKEG 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 939106619 174 YAPVeFFLEGTRSRSAKTLTPKFGLLNIVMEpffkrevFDTYLVPISISYdkileeTLYVYELLGVPKPkesttgllkar 253
Cdd:cd07989 98 ESVV-IFPEGTRSRDGELLPFKSGAFRLAKE-------AGVPIVPVAISG------TWGSLPKGKKLPR----------- 152
|
170 180 190
....*....|....*....|....*....|
gi 939106619 254 kilsenFGSIHVYFGDPVSLRSLAAGRMSR 283
Cdd:cd07989 153 ------PGRVTVRIGEPIPPEGLELAEEDR 176
|
|
| |
