unique cartilage matrix-associated protein isoform 2 precursor [Homo sapiens]
List of domain hits
Name | Accession | Description | Interval | E-value | |||
UCMA super family | cl25314 | Unique cartilage matrix associated protein; UCMA is a secreted cartilage-specific protein ... |
1-102 | 1.57e-49 | |||
Unique cartilage matrix associated protein; UCMA is a secreted cartilage-specific protein located in chromosome 2 that is predominantly expressed in resting chondrocytes. It is secreted into the extracellular matrix as an uncleaved precursor and shows the same restricted distribution pattern in cartilage as UCMA mRNA. This protein is proteolytically processed and contains tyrosine sulfates. It seems to be to be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of foetal cartilage. The actual alignment was detected with superfamily member pfam17085: Pssm-ID: 293690 Cd Length: 134 Bit Score: 153.60 E-value: 1.57e-49
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Name | Accession | Description | Interval | E-value | |||
UCMA | pfam17085 | Unique cartilage matrix associated protein; UCMA is a secreted cartilage-specific protein ... |
1-102 | 1.57e-49 | |||
Unique cartilage matrix associated protein; UCMA is a secreted cartilage-specific protein located in chromosome 2 that is predominantly expressed in resting chondrocytes. It is secreted into the extracellular matrix as an uncleaved precursor and shows the same restricted distribution pattern in cartilage as UCMA mRNA. This protein is proteolytically processed and contains tyrosine sulfates. It seems to be to be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of foetal cartilage. Pssm-ID: 293690 Cd Length: 134 Bit Score: 153.60 E-value: 1.57e-49
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Name | Accession | Description | Interval | E-value | |||
UCMA | pfam17085 | Unique cartilage matrix associated protein; UCMA is a secreted cartilage-specific protein ... |
1-102 | 1.57e-49 | |||
Unique cartilage matrix associated protein; UCMA is a secreted cartilage-specific protein located in chromosome 2 that is predominantly expressed in resting chondrocytes. It is secreted into the extracellular matrix as an uncleaved precursor and shows the same restricted distribution pattern in cartilage as UCMA mRNA. This protein is proteolytically processed and contains tyrosine sulfates. It seems to be to be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of foetal cartilage. Pssm-ID: 293690 Cd Length: 134 Bit Score: 153.60 E-value: 1.57e-49
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Selenoprotein_S | pfam06936 | Selenoprotein S (SelS); This family consists of several mammalian selenoprotein S (SelS) ... |
7-87 | 4.85e-03 | |||
Selenoprotein S (SelS); This family consists of several mammalian selenoprotein S (SelS) sequences. SelS is a plasma membrane protein and is present in a variety of tissues and cell types. Selenoprotein S (SelS) is an intrinsically disordered protein. It formsa selenosulfide bond between cys 174 and Sec 188, that has a redox potential -234 mV. In vitro, SelS is an efficient reductase that depends on the presence of selenocysteine. Due to the high reactivity, SelS also has peroxidase activity that can catalyze the reduction of hydrogen peroxide. It is also resistant to inactivation by hydrogen peroxide which might provide evolutionary advantage compared to cysteine containing peroxidases. Pssm-ID: 462043 [Multi-domain] Cd Length: 192 Bit Score: 34.43 E-value: 4.85e-03
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Blast search parameters | ||||
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