transmembrane protein 138 isoform 2 [Mus musculus]
Protein Classification
TMEM138 superfamily-containing protein( domain architecture ID 143948)
TMEM138 superfamily-containing protein
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| TMEM138 super family | cl20820 | Transmembrane protein 138; This family of proteins is found in eukaryotes and members are ... |
38-100 | 6.25e-17 | ||
Transmembrane protein 138; This family of proteins is found in eukaryotes and members are approximately 160 amino acids in length. There are two conserved sequence motifs: YYY and DPR. This transmembrane protein belongs to a family found in eukaryotes and is involved in the biogenesis and degradation of ciliated cells. Mutations in this protein cause the disease Joubert syndrome(JBTS) where the cilia becomes non-motile. Ciliopathy can be severe since cilia provide the cell with large amounts of information through signals. Ciliopathy can affect cell behaviour as the appropriate signals between the cell and its environment are not made, which can affect cell survival. The actual alignment was detected with superfamily member pfam14935: Pssm-ID: 434328 Cd Length: 119 Bit Score: 69.96 E-value: 6.25e-17
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| Name | Accession | Description | Interval | E-value | ||
| TMEM138 | pfam14935 | Transmembrane protein 138; This family of proteins is found in eukaryotes and members are ... |
38-100 | 6.25e-17 | ||
Transmembrane protein 138; This family of proteins is found in eukaryotes and members are approximately 160 amino acids in length. There are two conserved sequence motifs: YYY and DPR. This transmembrane protein belongs to a family found in eukaryotes and is involved in the biogenesis and degradation of ciliated cells. Mutations in this protein cause the disease Joubert syndrome(JBTS) where the cilia becomes non-motile. Ciliopathy can be severe since cilia provide the cell with large amounts of information through signals. Ciliopathy can affect cell behaviour as the appropriate signals between the cell and its environment are not made, which can affect cell survival. Pssm-ID: 434328 Cd Length: 119 Bit Score: 69.96 E-value: 6.25e-17
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| Name | Accession | Description | Interval | E-value | ||
| TMEM138 | pfam14935 | Transmembrane protein 138; This family of proteins is found in eukaryotes and members are ... |
38-100 | 6.25e-17 | ||
Transmembrane protein 138; This family of proteins is found in eukaryotes and members are approximately 160 amino acids in length. There are two conserved sequence motifs: YYY and DPR. This transmembrane protein belongs to a family found in eukaryotes and is involved in the biogenesis and degradation of ciliated cells. Mutations in this protein cause the disease Joubert syndrome(JBTS) where the cilia becomes non-motile. Ciliopathy can be severe since cilia provide the cell with large amounts of information through signals. Ciliopathy can affect cell behaviour as the appropriate signals between the cell and its environment are not made, which can affect cell survival. Pssm-ID: 434328 Cd Length: 119 Bit Score: 69.96 E-value: 6.25e-17
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