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Conserved domains on  [gi|683524007|ref|NP_001288657|]
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adrenodoxin, mitochondrial isoform 2 precursor [Mus musculus]

Protein Classification

2Fe-2S iron-sulfur cluster-binding family protein( domain architecture ID 1376)

2Fe-2S iron-sulfur cluster-binding family protein such as ferredoxin, an iron-sulfur protein transfering electrons in a wide variety of metabolic reactions

Gene Ontology:  GO:0051536

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
fer2 super family cl00159
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 71-150 1.70e-31

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


The actual alignment was detected with superfamily member PLN02593:

Pssm-ID: 444718 [Multi-domain]  Cd Length: 117  Bit Score: 109.42  E-value: 1.70e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 683524007  71 ITVHFKNRDGETLTTKGKIGDSLLDVVIENNLDIDGfgACEGTLACSTCHLIFED-HIYEKLDAITDEENDMLDLAFGLT 149
Cdd:PLN02593   1 ISVTFVDKDGEERTVKAPVGMSLLEAAHENDIELEG--ACEGSLACSTCHVIVMDeKVYNKLPEPTDEENDMLDLAFGLT 78


                 .
gi 683524007 150 D 150
Cdd:PLN02593  79 E 79
 
Name Accession Description Interval E-value
PLN02593 PLN02593
adrenodoxin-like ferredoxin protein
 71-150 1.70e-31

adrenodoxin-like ferredoxin protein


Pssm-ID: 178203 [Multi-domain]  Cd Length: 117  Bit Score: 109.42  E-value: 1.70e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 683524007  71 ITVHFKNRDGETLTTKGKIGDSLLDVVIENNLDIDGfgACEGTLACSTCHLIFED-HIYEKLDAITDEENDMLDLAFGLT 149
Cdd:PLN02593   1 ISVTFVDKDGEERTVKAPVGMSLLEAAHENDIELEG--ACEGSLACSTCHVIVMDeKVYNKLPEPTDEENDMLDLAFGLT 78


                 .
gi 683524007 150 D 150
Cdd:PLN02593  79 E 79
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 73-141 5.11e-04

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 36.99  E-value: 5.11e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 683524007  73 VHFkNRDGETLTTKGKIGDSLLDVVIENNLDIDGFgaCEGTlACSTCHLIFEDHIYEKLDAITDEENDM 141
Cdd:cd00207    1 VTI-NVPGSGVEVEVPEGETLLDAAREAGIDIPYS--CRAG-ACGTCKVEVVEGEVDQSDPSLLDEEEA 65
 
Name Accession Description Interval E-value
PLN02593 PLN02593
adrenodoxin-like ferredoxin protein
 71-150 1.70e-31

adrenodoxin-like ferredoxin protein


Pssm-ID: 178203 [Multi-domain]  Cd Length: 117  Bit Score: 109.42  E-value: 1.70e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 683524007  71 ITVHFKNRDGETLTTKGKIGDSLLDVVIENNLDIDGfgACEGTLACSTCHLIFED-HIYEKLDAITDEENDMLDLAFGLT 149
Cdd:PLN02593   1 ISVTFVDKDGEERTVKAPVGMSLLEAAHENDIELEG--ACEGSLACSTCHVIVMDeKVYNKLPEPTDEENDMLDLAFGLT 78


                 .
gi 683524007 150 D 150
Cdd:PLN02593  79 E 79
PTZ00490 PTZ00490
Ferredoxin superfamily; Provisional
 70-164 7.28e-09

Ferredoxin superfamily; Provisional


Pssm-ID: 185668  Cd Length: 143  Bit Score: 51.40  E-value: 7.28e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 683524007  70 KITVHFKNRDGETLTTKGKIGDSLLDVVIE-NNLDIDGfgACEGTLACSTCHLIFEDHIYEKLDAITDEENDMLDLAFGL 148
Cdd:PTZ00490  35 KVKVCVKKRDGTHCDVEVPVGMSLMHALRDvAKLDVEG--TCNGCMQCATCHVYLSAASFKKLGGPSEEEEDVLAKALDV 112

                         90
                 ....*....|....*.
gi 683524007 149 TDRNLEDPPISFSPAI 164
Cdd:PTZ00490 113 KETSRLACQVDLTPEM 128
fer2 cd00207
2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in ...
 73-141 5.11e-04

2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis and ferredoxins, which participate in redox chains (from bacteria to mammals). Fold is ismilar to thioredoxin.


Pssm-ID: 238126 [Multi-domain]  Cd Length: 84  Bit Score: 36.99  E-value: 5.11e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 683524007  73 VHFkNRDGETLTTKGKIGDSLLDVVIENNLDIDGFgaCEGTlACSTCHLIFEDHIYEKLDAITDEENDM 141
Cdd:cd00207    1 VTI-NVPGSGVEVEVPEGETLLDAAREAGIDIPYS--CRAG-ACGTCKVEVVEGEVDQSDPSLLDEEEA 65
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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