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syntaxin-18 isoform 2 [Mus musculus]
Syntaxin-18_N and SNARE_syntaxin18 domain-containing protein( domain architecture ID 10564682)
Syntaxin-18_N and SNARE_syntaxin18 domain-containing protein
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
SNARE_syntaxin18 | cd15850 | SNARE motif, subgroup Qa; Syntaxin18 (also known as Ufe1p) is involved in retrograde transport ... |
245-303 | 8.79e-22 | |||
SNARE motif, subgroup Qa; Syntaxin18 (also known as Ufe1p) is involved in retrograde transport of CopI coatomer coated vesicles from the Golgi to the ER. It forms a complex with USE1 (SLT1, Qc), Bnip1 (Sec20p, Qb) and Sec22b (R-SNARE). Syntaxin18 is a member of the Qa subfamily of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein family. SNARE proteins consist of coiled-coil helices (called SNARE motifs) which mediate the interactions between SNARE proteins, and a transmembrane domain. The SNARE complex mediates membrane fusion, important for trafficking of newly synthesized proteins, recycling of pre-existing proteins and organelle formation. SNARE proteins are classified into four groups, Qa-, Qb-, Qc- and R-SNAREs, depending on whether the residue in the hydrophilic center layer of the four-helical bundle is a glutamine (Q) or arginine (R). Qc-, as well as Qa- and Qb-SNAREs, are localized to target organelle membranes, while R-SNARE is localized to vesicle membranes. They form unique complexes consisting of one member of each subgroup, that mediate fusion between a specific type of vesicles and their target organelle. Their SNARE motifs form twisted and parallel heterotetrameric helix bundles. : Pssm-ID: 277203 Cd Length: 59 Bit Score: 86.58 E-value: 8.79e-22
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Syntaxin-18_N | pfam10496 | SNARE-complex protein Syntaxin-18 N-terminus; This is the conserved N-terminal of Syntaxin-18. ... |
4-96 | 1.98e-21 | |||
SNARE-complex protein Syntaxin-18 N-terminus; This is the conserved N-terminal of Syntaxin-18. Syntaxin-18 is found in the SNARE complex of the endoplasmic reticulum and functions in the trafficking between the ER intermediate compartment and the cis-Golgi vesicle. In particular, the N-terminal region is important for the formation of ER aggregates. More specifically, syntaxin-18 is involved in endoplasmic reticulum-mediated phagocytosis, presumably by regulating the specific and direct fusion of the ER with the plasma or phagosomal membranes. : Pssm-ID: 463116 Cd Length: 87 Bit Score: 86.32 E-value: 1.98e-21
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Name | Accession | Description | Interval | E-value | |||
SNARE_syntaxin18 | cd15850 | SNARE motif, subgroup Qa; Syntaxin18 (also known as Ufe1p) is involved in retrograde transport ... |
245-303 | 8.79e-22 | |||
SNARE motif, subgroup Qa; Syntaxin18 (also known as Ufe1p) is involved in retrograde transport of CopI coatomer coated vesicles from the Golgi to the ER. It forms a complex with USE1 (SLT1, Qc), Bnip1 (Sec20p, Qb) and Sec22b (R-SNARE). Syntaxin18 is a member of the Qa subfamily of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein family. SNARE proteins consist of coiled-coil helices (called SNARE motifs) which mediate the interactions between SNARE proteins, and a transmembrane domain. The SNARE complex mediates membrane fusion, important for trafficking of newly synthesized proteins, recycling of pre-existing proteins and organelle formation. SNARE proteins are classified into four groups, Qa-, Qb-, Qc- and R-SNAREs, depending on whether the residue in the hydrophilic center layer of the four-helical bundle is a glutamine (Q) or arginine (R). Qc-, as well as Qa- and Qb-SNAREs, are localized to target organelle membranes, while R-SNARE is localized to vesicle membranes. They form unique complexes consisting of one member of each subgroup, that mediate fusion between a specific type of vesicles and their target organelle. Their SNARE motifs form twisted and parallel heterotetrameric helix bundles. Pssm-ID: 277203 Cd Length: 59 Bit Score: 86.58 E-value: 8.79e-22
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Syntaxin-18_N | pfam10496 | SNARE-complex protein Syntaxin-18 N-terminus; This is the conserved N-terminal of Syntaxin-18. ... |
4-96 | 1.98e-21 | |||
SNARE-complex protein Syntaxin-18 N-terminus; This is the conserved N-terminal of Syntaxin-18. Syntaxin-18 is found in the SNARE complex of the endoplasmic reticulum and functions in the trafficking between the ER intermediate compartment and the cis-Golgi vesicle. In particular, the N-terminal region is important for the formation of ER aggregates. More specifically, syntaxin-18 is involved in endoplasmic reticulum-mediated phagocytosis, presumably by regulating the specific and direct fusion of the ER with the plasma or phagosomal membranes. Pssm-ID: 463116 Cd Length: 87 Bit Score: 86.32 E-value: 1.98e-21
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Name | Accession | Description | Interval | E-value | |||
SNARE_syntaxin18 | cd15850 | SNARE motif, subgroup Qa; Syntaxin18 (also known as Ufe1p) is involved in retrograde transport ... |
245-303 | 8.79e-22 | |||
SNARE motif, subgroup Qa; Syntaxin18 (also known as Ufe1p) is involved in retrograde transport of CopI coatomer coated vesicles from the Golgi to the ER. It forms a complex with USE1 (SLT1, Qc), Bnip1 (Sec20p, Qb) and Sec22b (R-SNARE). Syntaxin18 is a member of the Qa subfamily of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) protein family. SNARE proteins consist of coiled-coil helices (called SNARE motifs) which mediate the interactions between SNARE proteins, and a transmembrane domain. The SNARE complex mediates membrane fusion, important for trafficking of newly synthesized proteins, recycling of pre-existing proteins and organelle formation. SNARE proteins are classified into four groups, Qa-, Qb-, Qc- and R-SNAREs, depending on whether the residue in the hydrophilic center layer of the four-helical bundle is a glutamine (Q) or arginine (R). Qc-, as well as Qa- and Qb-SNAREs, are localized to target organelle membranes, while R-SNARE is localized to vesicle membranes. They form unique complexes consisting of one member of each subgroup, that mediate fusion between a specific type of vesicles and their target organelle. Their SNARE motifs form twisted and parallel heterotetrameric helix bundles. Pssm-ID: 277203 Cd Length: 59 Bit Score: 86.58 E-value: 8.79e-22
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Syntaxin-18_N | pfam10496 | SNARE-complex protein Syntaxin-18 N-terminus; This is the conserved N-terminal of Syntaxin-18. ... |
4-96 | 1.98e-21 | |||
SNARE-complex protein Syntaxin-18 N-terminus; This is the conserved N-terminal of Syntaxin-18. Syntaxin-18 is found in the SNARE complex of the endoplasmic reticulum and functions in the trafficking between the ER intermediate compartment and the cis-Golgi vesicle. In particular, the N-terminal region is important for the formation of ER aggregates. More specifically, syntaxin-18 is involved in endoplasmic reticulum-mediated phagocytosis, presumably by regulating the specific and direct fusion of the ER with the plasma or phagosomal membranes. Pssm-ID: 463116 Cd Length: 87 Bit Score: 86.32 E-value: 1.98e-21
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Blast search parameters | ||||
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