NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|567316040|ref|NP_001274526|]
View 

excitatory amino acid transporter 5 isoform 3 [Homo sapiens]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10003465)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
15-403 1.08e-91

Na+/H+-dicarboxylate symporter [Energy production and conversion];


:

Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 284.31  E-value: 1.08e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  15 RRNGLLILSVLSVIVGCLLGFFLRtrrlsPQEISYFQFPGELLMRMLKMMILPLVVSrnmfpaNLVEATFKQYRTKttpv 94
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLP-----ELVAAVLKPLGDIFINLLKMIVVPLVFF------SIVVGIASLGDLK---- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  95 vKSPKVApeeappRRILIY---------------------GVqeengshvqNFALDLTPPPEVVYKSEPGTSD------- 146
Cdd:COG1301   66 -KLGRIG------GKTLLYflvtttialviglvvanlfqpGA---------GLNLDLADAAAAEAAEAPSLLDfllniip 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 147 --------GMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDprAVG 218
Cdd:COG1301  130 snifeafaEGNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGL--DAL 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 219 KKLGFYSVTVVCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVL 298
Cdd:COG1301  208 GSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVL 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 299 PVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAV 378
Cdd:COG1301  288 PLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGI 367

                        410       420
                 ....*....|....*....|....*
gi 567316040 379 DWALDRFRTMINVLGDALAAGIMAH 403
Cdd:COG1301  368 DRILDMARTAVNVTGDAVATVVVAK 392
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
15-403 1.08e-91

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 284.31  E-value: 1.08e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  15 RRNGLLILSVLSVIVGCLLGFFLRtrrlsPQEISYFQFPGELLMRMLKMMILPLVVSrnmfpaNLVEATFKQYRTKttpv 94
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLP-----ELVAAVLKPLGDIFINLLKMIVVPLVFF------SIVVGIASLGDLK---- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  95 vKSPKVApeeappRRILIY---------------------GVqeengshvqNFALDLTPPPEVVYKSEPGTSD------- 146
Cdd:COG1301   66 -KLGRIG------GKTLLYflvtttialviglvvanlfqpGA---------GLNLDLADAAAAEAAEAPSLLDfllniip 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 147 --------GMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDprAVG 218
Cdd:COG1301  130 snifeafaEGNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGL--DAL 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 219 KKLGFYSVTVVCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVL 298
Cdd:COG1301  208 GSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVL 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 299 PVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAV 378
Cdd:COG1301  288 PLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGI 367

                        410       420
                 ....*....|....*....|....*
gi 567316040 379 DWALDRFRTMINVLGDALAAGIMAH 403
Cdd:COG1301  368 DRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
19-404 1.49e-90

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 280.56  E-value: 1.49e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040   19 LLILSVLSVIVGCLLGFFLrtrrlsPQEISYFQFPGELLMRMLKMMILPLVVS------RNMFPAN----LVEATFKQYR 88
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF------PELAAWLKPLGDLFIRLLKMIIVPLIFAsiisgiASLGDGKklgkLGGKTLLYFL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040   89 TKTT---------PVVKSPKvapEEAPPRRILIYGVQEENGSHVQNFALDLTPPPEVVYKSEPgtsdgmNVLGIVFFSAT 159
Cdd:pfam00375  75 VTTAiaaligllvANVFQPG---SGLALIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG------NVLAVIVFAIL 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  160 MGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDdpRAVGKKLGFYSVTVVCGLVLHGLFI 239
Cdd:pfam00375 146 FGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGTYG--LGILSSLAKFLLVVYLGLAIHLLIV 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  240 LPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTALYEAVAAIF 319
Cdd:pfam00375 224 YPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIF 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  320 IAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAG 399
Cdd:pfam00375 304 IAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAV 383


                  ....*
gi 567316040  400 IMAHI 404
Cdd:pfam00375 384 IVAKL 388
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 149-402 3.56e-28

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 115.92  E-value: 3.56e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 149 NVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIA---GKiLEMDDPRAVGKKLG-FY 224
Cdd:PRK13027 149 DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPLGVLGAIAfttGK-YGVGSLKQLGMLVAvFY 227

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 225 S-----VTVVCGLV--LHGLFILPLlyffitkknpivfIRGILQALLIALATSSSSATLPITFKcLLENNHIDRRIARFV 297
Cdd:PRK13027 228 LtcfvfVVVVLGAVmrLAGFSVFKL-------------IRYLREELLIVLGTASSDAVLPQVMR-KLEHMGIKDSTVGLV 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 298 LPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LPTDDITLII 376
Cdd:PRK13027 294 IPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLIL 373

                        250       260
                 ....*....|....*....|....*.
gi 567316040 377 AVDWALDRFRTMINVLGDALAAGIMA 402
Cdd:PRK13027 374 PVDWFMGIARALTNLIGNCVATVVVA 399
 
Name Accession Description Interval E-value
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
15-403 1.08e-91

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 284.31  E-value: 1.08e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  15 RRNGLLILSVLSVIVGCLLGFFLRtrrlsPQEISYFQFPGELLMRMLKMMILPLVVSrnmfpaNLVEATFKQYRTKttpv 94
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLP-----ELVAAVLKPLGDIFINLLKMIVVPLVFF------SIVVGIASLGDLK---- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  95 vKSPKVApeeappRRILIY---------------------GVqeengshvqNFALDLTPPPEVVYKSEPGTSD------- 146
Cdd:COG1301   66 -KLGRIG------GKTLLYflvtttialviglvvanlfqpGA---------GLNLDLADAAAAEAAEAPSLLDfllniip 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 147 --------GMNVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDDprAVG 218
Cdd:COG1301  130 snifeafaEGNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMKLAPIGVFALIAATVAKYGL--DAL 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 219 KKLGFYSVTVVCGLVLHGLFILPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVL 298
Cdd:COG1301  208 GSLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEATLPVTMEKAEEKLGVSKSVASFVL 287

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 299 PVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAV 378
Cdd:COG1301  288 PLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAGLVMLAAVLSAVGLPLEGIALILGI 367

                        410       420
                 ....*....|....*....|....*
gi 567316040 379 DWALDRFRTMINVLGDALAAGIMAH 403
Cdd:COG1301  368 DRILDMARTAVNVTGDAVATVVVAK 392
SDF pfam00375
Sodium:dicarboxylate symporter family;
19-404 1.49e-90

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 280.56  E-value: 1.49e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040   19 LLILSVLSVIVGCLLGFFLrtrrlsPQEISYFQFPGELLMRMLKMMILPLVVS------RNMFPAN----LVEATFKQYR 88
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF------PELAAWLKPLGDLFIRLLKMIIVPLIFAsiisgiASLGDGKklgkLGGKTLLYFL 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040   89 TKTT---------PVVKSPKvapEEAPPRRILIYGVQEENGSHVQNFALDLTPPPEVVYKSEPgtsdgmNVLGIVFFSAT 159
Cdd:pfam00375  75 VTTAiaaligllvANVFQPG---SGLALIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG------NVLAVIVFAIL 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  160 MGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEMDdpRAVGKKLGFYSVTVVCGLVLHGLFI 239
Cdd:pfam00375 146 FGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPIGVFALIANTVGTYG--LGILSSLAKFLLVVYLGLAIHLLIV 223

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  240 LPLLYFFITKKNPIVFIRGILQALLIALATSSSSATLPITFKCLLENNHIDRRIARFVLPVGATINMDGTALYEAVAAIF 319
Cdd:pfam00375 224 YPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPVTLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIF 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040  320 IAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWALDRFRTMINVLGDALAAG 399
Cdd:pfam00375 304 IAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAV 383


                  ....*
gi 567316040  400 IMAHI 404
Cdd:pfam00375 384 IVAKL 388
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 149-402 3.56e-28

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 115.92  E-value: 3.56e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 149 NVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIA---GKiLEMDDPRAVGKKLG-FY 224
Cdd:PRK13027 149 DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPLGVLGAIAfttGK-YGVGSLKQLGMLVAvFY 227

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 225 S-----VTVVCGLV--LHGLFILPLlyffitkknpivfIRGILQALLIALATSSSSATLPITFKcLLENNHIDRRIARFV 297
Cdd:PRK13027 228 LtcfvfVVVVLGAVmrLAGFSVFKL-------------IRYLREELLIVLGTASSDAVLPQVMR-KLEHMGIKDSTVGLV 293

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 298 LPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LPTDDITLII 376
Cdd:PRK13027 294 IPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLVLIL 373

                        250       260
                 ....*....|....*....|....*.
gi 567316040 377 AVDWALDRFRTMINVLGDALAAGIMA 402
Cdd:PRK13027 374 PVDWFMGIARALTNLIGNCVATVVVA 399
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 150-402 3.90e-28

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 116.02  E-value: 3.90e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 150 VLGIVFFSATMGIMLGRM-GDSGAPLVSFCQCLNESVMKIVAVAVWYFPFGIVFLIAGKIlemddpravgKKLGFYSVTV 228
Cdd:PRK11283 160 MLPIIFFSVLFGLGLSSLpATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTV----------ANFGFASLWP 229

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 229 VCGLVLhgLFILPLLYFF---------ITKKNPIVFIRGILQALLIALATSSSSATLPITFKcLLENNHIDRRIARFVLP 299
Cdd:PRK11283 230 LAKLVL--LVYFAILFFAlvvlgivarLCGLSIWILIRILKDELILAYSTASSETVLPRIIE-KMEAYGAPKSITSFVVP 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 300 VGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVD 379
Cdd:PRK11283 307 TGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVD 386

                        250       260
                 ....*....|....*....|...
gi 567316040 380 WALDRFRTMINVLGDALAAGIMA 402
Cdd:PRK11283 387 RILDMARTALNVVGNALAVLVIA 409
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 149-412 3.20e-27

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 113.07  E-value: 3.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 149 NVLGIVFFSATMGIMLGRMGDSGAPLVSFCQCLNESVMKIVAVAVWYFPFG----IVFLIA----GKILEMddpravGKK 220
Cdd:PRK01663 149 DILQVLLFAVLFGFALARLGEKGKPVFDFIESLSHVLFGIVNMIMKLAPIGafgaMAFTIGkygvGSLVQL------GQL 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 221 LG-FYS-----VTVVCGLV--LHGLFILPllyffitkknpivFIRGILQALLIALATSSSSATLP-ITFKclLENNHIDR 291
Cdd:PRK01663 223 IGcFYItcilfVFVVLGAIarLTGFSIFK-------------FIRYIKEELLIVLGTSSSESALPrMMEK--MEKLGCKK 287

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 292 RIARFVLPVGATINMDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVG-LPTD 370
Cdd:PRK01663 288 SVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVA 367

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 567316040 371 DITLIIAVDWALDRFRTMINVLGDALAAGIMAHICrKDFARD 412
Cdd:PRK01663 368 GLALILGIDRFMSEARALTNLIGNGVATVVVAKWE-KELDRE 408
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 149-400 5.92e-10

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 60.45  E-value: 5.92e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 149 NVLGIVFFSATMGIMLGRMGDSGAPLVsfcQCLNESVMKIVAVAVWYFPFGIVFLIAGKILEmddpRAVGK--KLGFYSV 226
Cdd:PRK14695  60 NYIGILSWAVIFGIAMREASKNSKELL---KTIADVTSKIVEWIINLAPFGILGLVFKTISD----KGVGSlaNYGILLV 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 227 TVVCGLVLHGLFILPLLYFFITKKNPIVFIRGILQ-ALLIALATSSSSATLPITFKcLLENNHIDRRIARFVLPVGATIN 305
Cdd:PRK14695 133 LLVTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTIN 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 306 MDGTALYEAVAAIFIAQVNNYELDFGQIITISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWAL--- 382
Cdd:PRK14695 212 MAGVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGISNDIAIQIVGVGFVIgvi 291

                        250
                 ....*....|....*....
gi 567316040 383 -DRFRTMINVLGDALAAGI 400
Cdd:PRK14695 292 qDSCETALNSSTDVLFTAV 310
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 149-350 1.89e-08

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 56.41  E-value: 1.89e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 149 NVLGIVFFSATMGIMLGRMGDSGAPLVsfcQCLNESVMKIVAVAVWYFPFGIVFLIAGKILE--MDDPRAVGKKLGfysV 226
Cdd:PRK13628 146 NYIGILAWAIGLGLALRHASDTTKNVV---NDLSEAVSQIVKWVIRFAPIGIFGLVASTLAEtgFSALAGYAQLLA---V 219

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 227 TVVCGLVLhGLFILPLLYFFITKKNP--IVFiRGILQALLIALATSSSSATLPITFKcLLENNHIDRRIARFVLPVGATI 304
Cdd:PRK13628 220 LVGCMLFV-ALVVNPLIVFWKIRRNPypLVF-TCLRESGVTAFFTRSSAANIPVNMA-LCEKLGLDEDTYSVSIPLGATI 296

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 567316040 305 NMDGtalyeavAAIFI-----AQVN--NYELDFGQIITISITATAASIGAAGI 350
Cdd:PRK13628 297 NMAG-------AAITItvltlAAVHtlGIPVDLPTALLLSVVAAISACGASGV 342
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
149-351 7.79e-08

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 54.41  E-value: 7.79e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 149 NVLGIVFFSATMGIMLGRMGDSGAPLVSfcqCLNESVMKIVAVAVWYFPFGIVFLIAGKILEmddpraVG-KKLGFYS-- 225
Cdd:COG3633  145 NYIGILAWAIGLGLALRHASDTTKTVLS---DLSDAVSKIVRWVIRFAPLGIFGLVASTVAT------TGfSALLGYAhl 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 567316040 226 --VTVVCGLVLhGLFILPLLYFFITKKNP--IVFiRGILQALLIALATSSSSATLPITFKcLLENNHIDRRIARFVLPVG 301
Cdd:COG3633  216 laVLVGCMLFV-ALVVNPLIVFLKIRRNPypLVF-TCLRESGITAFFTRSSAANIPVNMA-LCEKLGLDEDTYSVSIPLG 292

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 567316040 302 ATINMDGtalyeavAAIFI-----AQVN--NYELDFGQIITISITATAASIGAAGIP 351
Cdd:COG3633  293 ATINMAG-------AAITItvltlAAVHtlGIEVDLPTALLLSVVAAVSACGASGVA 342
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH