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Conserved domains on  [gi|428977040|ref|NP_001258798|]
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SUZ RNA-binding domain-containing isoform 3 [Homo sapiens]

Protein Classification

SUZ and SUZ-C domain-containing protein( domain architecture ID 10579291)

SUZ and SUZ-C domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SUZ-C pfam12901
SUZ-C motif; The SUZ-C domain is a conserved motif found in one or more copies in several ...
118-150 3.76e-10

SUZ-C motif; The SUZ-C domain is a conserved motif found in one or more copies in several RNA-binding proteins. It is always found at the C-terminus of the protein and appear to be required for localization of the protein to specific subcellular structures. It was first characterized in the C.elegans protein Szy-20 which localizes to the centrosome. It is widely distributed in eukaryotes.


:

Pssm-ID: 463745  Cd Length: 33  Bit Score: 51.77  E-value: 3.76e-10
                          10        20        30
                  ....*....|....*....|....*....|...
gi 428977040  118 RPTRISQPEDSRQPNNVIRQPLGPDGSQGFKQR 150
Cdd:pfam12901   1 RLKSVSLDDANRPNNNVLRQPRGPDGSKGFRQR 33
SUZ pfam12752
SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched ...
55-106 5.06e-10

SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched in positively charged amino acids. It was first characterized in the C.elegans protein Szy-20 where it has been shown to bind RNA and allow their localization to the centrosome. Warning- the domain has a compositionally biased character.


:

Pssm-ID: 463689 [Multi-domain]  Cd Length: 56  Bit Score: 51.94  E-value: 5.06e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 428977040   55 PPPQIRILKRPTSNGVVSSPNSTSRPTL----PVKSLAQREAEYAEARKRILGSAS 106
Cdd:pfam12752   1 PPPKMKILRRPSSGSSSSSSAGSSGASSssgsDSKTLEEREAEYAEARARIFGSSE 56
 
Name Accession Description Interval E-value
SUZ-C pfam12901
SUZ-C motif; The SUZ-C domain is a conserved motif found in one or more copies in several ...
118-150 3.76e-10

SUZ-C motif; The SUZ-C domain is a conserved motif found in one or more copies in several RNA-binding proteins. It is always found at the C-terminus of the protein and appear to be required for localization of the protein to specific subcellular structures. It was first characterized in the C.elegans protein Szy-20 which localizes to the centrosome. It is widely distributed in eukaryotes.


Pssm-ID: 463745  Cd Length: 33  Bit Score: 51.77  E-value: 3.76e-10
                          10        20        30
                  ....*....|....*....|....*....|...
gi 428977040  118 RPTRISQPEDSRQPNNVIRQPLGPDGSQGFKQR 150
Cdd:pfam12901   1 RLKSVSLDDANRPNNNVLRQPRGPDGSKGFRQR 33
SUZ pfam12752
SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched ...
55-106 5.06e-10

SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched in positively charged amino acids. It was first characterized in the C.elegans protein Szy-20 where it has been shown to bind RNA and allow their localization to the centrosome. Warning- the domain has a compositionally biased character.


Pssm-ID: 463689 [Multi-domain]  Cd Length: 56  Bit Score: 51.94  E-value: 5.06e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 428977040   55 PPPQIRILKRPTSNGVVSSPNSTSRPTL----PVKSLAQREAEYAEARKRILGSAS 106
Cdd:pfam12752   1 PPPKMKILRRPSSGSSSSSSAGSSGASSssgsDSKTLEEREAEYAEARARIFGSSE 56
 
Name Accession Description Interval E-value
SUZ-C pfam12901
SUZ-C motif; The SUZ-C domain is a conserved motif found in one or more copies in several ...
118-150 3.76e-10

SUZ-C motif; The SUZ-C domain is a conserved motif found in one or more copies in several RNA-binding proteins. It is always found at the C-terminus of the protein and appear to be required for localization of the protein to specific subcellular structures. It was first characterized in the C.elegans protein Szy-20 which localizes to the centrosome. It is widely distributed in eukaryotes.


Pssm-ID: 463745  Cd Length: 33  Bit Score: 51.77  E-value: 3.76e-10
                          10        20        30
                  ....*....|....*....|....*....|...
gi 428977040  118 RPTRISQPEDSRQPNNVIRQPLGPDGSQGFKQR 150
Cdd:pfam12901   1 RLKSVSLDDANRPNNNVLRQPRGPDGSKGFRQR 33
SUZ pfam12752
SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched ...
55-106 5.06e-10

SUZ domain; The SUZ domain is a conserved RNA-binding domain found in eukaryotes and enriched in positively charged amino acids. It was first characterized in the C.elegans protein Szy-20 where it has been shown to bind RNA and allow their localization to the centrosome. Warning- the domain has a compositionally biased character.


Pssm-ID: 463689 [Multi-domain]  Cd Length: 56  Bit Score: 51.94  E-value: 5.06e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 428977040   55 PPPQIRILKRPTSNGVVSSPNSTSRPTL----PVKSLAQREAEYAEARKRILGSAS 106
Cdd:pfam12752   1 PPPKMKILRRPSSGSSSSSSAGSSGASSssgsDSKTLEEREAEYAEARARIFGSSE 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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