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Conserved domains on  [gi|402534571|ref|NP_001257951|]
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ATR-interacting protein isoform 3 [Homo sapiens]

Protein Classification

OmpH family outer membrane protein( domain architecture ID 12048616)

OmpH family outer membrane protein may play an active role either as folding catalysts or as chaperones in extracytoplasmic compartments; similar to Flavobacterium psychrophilum outer membrane protein P18

Gene Ontology:  GO:0051082|GO:0016020
PubMed:  2318304

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OmpH pfam03938
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 2-80 7.04e-04

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


:

Pssm-ID: 461098 [Multi-domain]  Cd Length: 140  Bit Score: 40.25  E-value: 7.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 402534571    2 KVMEEEVLIKNGEIKILRDSLHQTESVLEEQRrshflleQEKTQALSDKEKEFSKKLQSLQSELQFKDAE-MNELRTKLQ 80
Cdd:pfam03938  29 KKRQAELEAKQKELQKLYEELQKDGALLEEER-------EEKEQELQKKEQELQQLQQKAQQELQKKQQElLQPIQDKIN 101
 
Name Accession Description Interval E-value
OmpH pfam03938
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 2-80 7.04e-04

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 461098 [Multi-domain]  Cd Length: 140  Bit Score: 40.25  E-value: 7.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 402534571    2 KVMEEEVLIKNGEIKILRDSLHQTESVLEEQRrshflleQEKTQALSDKEKEFSKKLQSLQSELQFKDAE-MNELRTKLQ 80
Cdd:pfam03938  29 KKRQAELEAKQKELQKLYEELQKDGALLEEER-------EEKEQELQKKEQELQQLQQKAQQELQKKQQElLQPIQDKIN 101
OmpH smart00935
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 1-81 5.34e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 214922 [Multi-domain]  Cd Length: 140  Bit Score: 37.56  E-value: 5.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 402534571     1 MKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRShfLLEQEKT---QALSDKEKEFSKKLQSLQSELQFKDAE-MNELR 76
Cdd:smart00935  20 QKQLEKEFKKRQAELEKLEKELQKLKEKLQKDAAT--LSEAAREkkeKELQKKVQEFQRKQQKLQQDLQKRQQEeLQKIL 97


                   ....*
gi 402534571    77 TKLQT 81
Cdd:smart00935  98 DKINK 102
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1-87 6.25e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.50  E-value: 6.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 402534571   1 MKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRshfllEQEKTQA-LSDKEKEFSKKLQSL---QSELQFKDAEMNELR 76
Cdd:COG4372   40 LDKLQEELEQLREELEQAREELEQLEEELEQARS-----ELEQLEEeLEELNEQLQAAQAELaqaQEELESLQEEAEELQ 114

                         90
                 ....*....|.
gi 402534571  77 TKLQTSERANK 87
Cdd:COG4372  115 EELEELQKERQ 125
 
Name Accession Description Interval E-value
OmpH pfam03938
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 2-80 7.04e-04

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 461098 [Multi-domain]  Cd Length: 140  Bit Score: 40.25  E-value: 7.04e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 402534571    2 KVMEEEVLIKNGEIKILRDSLHQTESVLEEQRrshflleQEKTQALSDKEKEFSKKLQSLQSELQFKDAE-MNELRTKLQ 80
Cdd:pfam03938  29 KKRQAELEAKQKELQKLYEELQKDGALLEEER-------EEKEQELQKKEQELQQLQQKAQQELQKKQQElLQPIQDKIN 101
Prefoldin_2 pfam01920
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996.
 38-80 3.93e-03

Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996.


Pssm-ID: 396482 [Multi-domain]  Cd Length: 102  Bit Score: 37.20  E-value: 3.93e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 402534571   38 LLEQEKTQALSD--KEKEF-SKKLQSLQSELQFKDAEMNELRTKLQ 80
Cdd:pfam01920  52 LVKQDKEEVKEQleERKETlEKEIKTLEKQLEKLEKELEELKEELY 97
OmpH smart00935
Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH ...
 1-81 5.34e-03

Outer membrane protein (OmpH-like); This family includes outer membrane proteins such as OmpH among others. Skp (OmpH) has been characterized as a molecular chaperone that interacts with unfolded proteins as they emerge in the periplasm from the Sec translocation machinery.


Pssm-ID: 214922 [Multi-domain]  Cd Length: 140  Bit Score: 37.56  E-value: 5.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 402534571     1 MKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRShfLLEQEKT---QALSDKEKEFSKKLQSLQSELQFKDAE-MNELR 76
Cdd:smart00935  20 QKQLEKEFKKRQAELEKLEKELQKLKEKLQKDAAT--LSEAAREkkeKELQKKVQEFQRKQQKLQQDLQKRQQEeLQKIL 97


                   ....*
gi 402534571    77 TKLQT 81
Cdd:smart00935  98 DKINK 102
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1-87 6.25e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 39.50  E-value: 6.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 402534571   1 MKVMEEEVLIKNGEIKILRDSLHQTESVLEEQRRshfllEQEKTQA-LSDKEKEFSKKLQSL---QSELQFKDAEMNELR 76
Cdd:COG4372   40 LDKLQEELEQLREELEQAREELEQLEEELEQARS-----ELEQLEEeLEELNEQLQAAQAELaqaQEELESLQEEAEELQ 114

                         90
                 ....*....|.
gi 402534571  77 TKLQTSERANK 87
Cdd:COG4372  115 EELEELQKERQ 125
DUF641 pfam04859
Plant protein of unknown function (DUF641); Plant protein of unknown function.
 61-87 6.92e-03

Plant protein of unknown function (DUF641); Plant protein of unknown function.


Pssm-ID: 461458 [Multi-domain]  Cd Length: 127  Bit Score: 37.19  E-value: 6.92e-03
                          10        20
                  ....*....|....*....|....*..
gi 402534571   61 LQSELQFKDAEMNELRTKLQTSERANK 87
Cdd:pfam04859  96 LEAELKAKDSEIDSLREKLDEAERSNR 122
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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