NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|374671785|ref|NP_001243440|]
View 

single-stranded DNA-binding protein, mitochondrial precursor [Homo sapiens]

Protein Classification

single-stranded DNA-binding protein( domain architecture ID 10015717)

single-stranded DNA (ssDNA)-binding protein plays a key role in DNA replication, recombination, and repair

CATH:  2.40.50.140
Gene Ontology:  GO:0003697|GO:0006260
PubMed:  27838363
SCOP:  4000346

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 27-141 1.28e-51

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 161.43  E-value: 1.28e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785   27 ERSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDsevyqlGDVSQKTTWHRISVFRPgLRDVAYQYVKKGS 106
Cdd:TIGR00621   1 MRMVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQD------GEWKEETEWHDIVIFGR-LAEVAAQYLKKGS 73

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 374671785  107 RIYLEGKIDYGEYMDKNNVRRQATTIIADNIIFLS 141
Cdd:TIGR00621  74 LVYVEGRLRTRKWEDQNGQKRSKTEIIADNVQLLD 108
 
Name Accession Description Interval E-value
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 27-141 1.28e-51

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 161.43  E-value: 1.28e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785   27 ERSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDsevyqlGDVSQKTTWHRISVFRPgLRDVAYQYVKKGS 106
Cdd:TIGR00621   1 MRMVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQD------GEWKEETEWHDIVIFGR-LAEVAAQYLKKGS 73

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 374671785  107 RIYLEGKIDYGEYMDKNNVRRQATTIIADNIIFLS 141
Cdd:TIGR00621  74 LVYVEGRLRTRKWEDQNGQKRSKTEIIADNVQLLD 108
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 30-140 1.09e-34

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 116.57  E-value: 1.09e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785   30 LNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGdsevyqlGDVSQKTTWHRISVFRPgLRDVAYQYVKKGSRIY 109
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDR-------GEGDEETDFHRVVVFGK-LAEVAAQYLKKGSLVY 72

                          90       100       110
                  ....*....|....*....|....*....|.
gi 374671785  110 LEGKIDYGEYMDKNNVRRQATTIIADNIIFL 140
Cdd:pfam00436  73 VEGRLQTRKYEDQEGQKRYVTEIVADEVQFL 103
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 33-140 1.07e-31

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 108.85  E-value: 1.07e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  33 VHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDsevyqlgDVSQKTTWHRISVFRPgLRDVAYQYVKKGSRIYLEG 112
Cdd:cd04496    1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRD-------EEEEETDWIRVVAFGK-LAENAAKYLKKGDLVYVEG 72

                         90       100
                 ....*....|....*....|....*...
gi 374671785 113 KIDYGEYMDKNNVRRQATTIIADNIIFL 140
Cdd:cd04496   73 RLRTRSWEDKDGQKRYGTEVVADRIEFL 100
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
30-141 7.73e-31

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 107.23  E-value: 7.73e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  30 LNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDsevyqlGDVSQKTTWHRISVFRpGLRDVAYQYVKKGSRIY 109
Cdd:COG0629    1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQD------GEWKDETDWHRVVAWG-KLAENAAEYLKKGDKVY 73

                         90       100       110
                 ....*....|....*....|....*....|..
gi 374671785 110 LEGKIDYGEYMDKNNVRRQATTIIADNIIFLS 141
Cdd:COG0629   74 VEGRLRTRSWEDKDGQKRYTTEVVADEIQFLG 105
PRK06341 PRK06341
single-stranded DNA-binding protein; Provisional
 29-136 1.17e-24

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235782 [Multi-domain]  Cd Length: 166  Bit Score: 92.94  E-value: 1.17e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  29 SLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSevyqlGDVSQKTTWHRISVFRPGLRDVAYQYVKKGSRI 108
Cdd:PRK06341   4 SVNKVILIGNLGADPEIRRTQDGRPIANLRIATSETWRDRNS-----GERKEKTEWHRVVIFNEGLCKVAEQYLKKGAKV 78

                         90       100
                 ....*....|....*....|....*...
gi 374671785 109 YLEGKIDYGEYMDKNNVRRQATTIIADN 136
Cdd:PRK06341  79 YIEGQLQTRKWTDQSGVERYSTEVVLQG 106
 
Name Accession Description Interval E-value
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 27-141 1.28e-51

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 161.43  E-value: 1.28e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785   27 ERSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDsevyqlGDVSQKTTWHRISVFRPgLRDVAYQYVKKGS 106
Cdd:TIGR00621   1 MRMVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQD------GEWKEETEWHDIVIFGR-LAEVAAQYLKKGS 73

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 374671785  107 RIYLEGKIDYGEYMDKNNVRRQATTIIADNIIFLS 141
Cdd:TIGR00621  74 LVYVEGRLRTRKWEDQNGQKRSKTEIIADNVQLLD 108
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 30-140 1.09e-34

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 116.57  E-value: 1.09e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785   30 LNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGdsevyqlGDVSQKTTWHRISVFRPgLRDVAYQYVKKGSRIY 109
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDR-------GEGDEETDFHRVVVFGK-LAEVAAQYLKKGSLVY 72

                          90       100       110
                  ....*....|....*....|....*....|.
gi 374671785  110 LEGKIDYGEYMDKNNVRRQATTIIADNIIFL 140
Cdd:pfam00436  73 VEGRLQTRKYEDQEGQKRYVTEIVADEVQFL 103
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 33-140 1.07e-31

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 108.85  E-value: 1.07e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  33 VHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDsevyqlgDVSQKTTWHRISVFRPgLRDVAYQYVKKGSRIYLEG 112
Cdd:cd04496    1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRD-------EEEEETDWIRVVAFGK-LAENAAKYLKKGDLVYVEG 72

                         90       100
                 ....*....|....*....|....*...
gi 374671785 113 KIDYGEYMDKNNVRRQATTIIADNIIFL 140
Cdd:cd04496   73 RLRTRSWEDKDGQKRYGTEVVADRIEFL 100
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
30-141 7.73e-31

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 107.23  E-value: 7.73e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  30 LNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDsevyqlGDVSQKTTWHRISVFRpGLRDVAYQYVKKGSRIY 109
Cdd:COG0629    1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQD------GEWKDETDWHRVVAWG-KLAENAAEYLKKGDKVY 73

                         90       100       110
                 ....*....|....*....|....*....|..
gi 374671785 110 LEGKIDYGEYMDKNNVRRQATTIIADNIIFLS 141
Cdd:COG0629   74 VEGRLRTRSWEDKDGQKRYTTEVVADEIQFLG 105
PRK06341 PRK06341
single-stranded DNA-binding protein; Provisional
 29-136 1.17e-24

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235782 [Multi-domain]  Cd Length: 166  Bit Score: 92.94  E-value: 1.17e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  29 SLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSevyqlGDVSQKTTWHRISVFRPGLRDVAYQYVKKGSRI 108
Cdd:PRK06341   4 SVNKVILIGNLGADPEIRRTQDGRPIANLRIATSETWRDRNS-----GERKEKTEWHRVVIFNEGLCKVAEQYLKKGAKV 78

                         90       100
                 ....*....|....*....|....*...
gi 374671785 109 YLEGKIDYGEYMDKNNVRRQATTIIADN 136
Cdd:PRK06341  79 YIEGQLQTRKWTDQSGVERYSTEVVLQG 106
PRK05733 PRK05733
single-stranded DNA-binding protein; Provisional
 26-135 5.03e-23

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235585 [Multi-domain]  Cd Length: 172  Bit Score: 88.83  E-value: 5.03e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  26 LERSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGdsevyQLGDVSQKTTWHRISVFRPgLRDVAYQYVKKG 105
Cdd:PRK05733   1 MARGVNKVILVGTCGQDPEVRYLPNGNAVTNLSLATSEQWTDK-----QSGQKVERTEWHRVSLFGK-VAEIAGEYLRKG 74

                         90       100       110
                 ....*....|....*....|....*....|
gi 374671785 106 SRIYLEGKIDYGEYmDKNNVRRQATTIIAD 135
Cdd:PRK05733  75 SQVYIEGKLQTREW-EKDGIKRYTTEIVVD 103
PRK06642 PRK06642
single-stranded DNA-binding protein; Provisional
 29-136 1.64e-20

single-stranded DNA-binding protein; Provisional


Pssm-ID: 135984  Cd Length: 152  Bit Score: 81.69  E-value: 1.64e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  29 SLNRVHLLGRVGQDPVLRQV-EGKNPVTIfSLATNEMWRSGDSevyqlGDVSQKTTWHRISVFRPGLRDVAYQYVKKGSR 107
Cdd:PRK06642   4 SLNKVILIGNVGRDPEIRTTgEGKKIINL-SLATTETWKDRIT-----SERKERTEWHRVVIFSEGLVSVVERYVTKGSK 77

                         90       100
                 ....*....|....*....|....*....
gi 374671785 108 IYLEGKIDYGEYMDKNNVRRQATTIIADN 136
Cdd:PRK06642  78 LYIEGSLQTRKWNDNSGQEKYTTEVVLQN 106
PRK09010 PRK09010
single-stranded DNA-binding protein; Provisional
 28-133 1.19e-19

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236362 [Multi-domain]  Cd Length: 177  Bit Score: 80.28  E-value: 1.19e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  28 RSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGdsevyQLGDVSQKTTWHRISVFRPgLRDVAYQYVKKGSR 107
Cdd:PRK09010   4 RGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK-----QTGEMKEQTEWHRVVLFGK-LAEVAGEYLRKGSQ 77

                         90       100
                 ....*....|....*....|....*.
gi 374671785 108 IYLEGKIDYGEYMDKNNVRRQATTII 133
Cdd:PRK09010  78 VYIEGQLRTRKWTDQSGQDRYTTEVV 103
PRK13732 PRK13732
single-stranded DNA-binding protein; Provisional
 28-133 1.86e-19

single-stranded DNA-binding protein; Provisional


Pssm-ID: 184284 [Multi-domain]  Cd Length: 175  Bit Score: 79.77  E-value: 1.86e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  28 RSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGdsevyQLGDVSQKTTWHRISVFRPgLRDVAYQYVKKGSR 107
Cdd:PRK13732   4 RGINKVILVGRLGKDPEVRYIPNGGAVANLQVATSESWRDK-----QTGEMREQTEWHRVVLFGK-LAEVAGEYLRKGAQ 77

                         90       100
                 ....*....|....*....|....*.
gi 374671785 108 IYLEGKIDYGEYMDkNNVRRQATTII 133
Cdd:PRK13732  78 VYIEGQLRTRSWED-NGITRYVTEIL 102
PRK08763 PRK08763
single-stranded DNA-binding protein; Provisional
 26-140 1.87e-18

single-stranded DNA-binding protein; Provisional


Pssm-ID: 181549 [Multi-domain]  Cd Length: 164  Bit Score: 76.90  E-value: 1.87e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  26 LERSLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDsevyqlGDVSQKTTWHRIsVFRPGLRDVAYQYVKKG 105
Cdd:PRK08763   1 MARGINKVILVGNLGNDPDIKYTQSGMTITRISLATTSVRKDRE------GNTQERTEWHRV-KFFGKLGEIAGEYLRKG 73

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 374671785 106 SRIYLEGKIDYGEYMDKNNVRRQATTIIADNIIFL 140
Cdd:PRK08763  74 SQCYIEGSIRYDKFTGQDGQERYVTEIVADEMQML 108
PRK06958 PRK06958
single-stranded DNA-binding protein; Provisional
 29-140 3.45e-17

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180777 [Multi-domain]  Cd Length: 182  Bit Score: 74.06  E-value: 3.45e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  29 SLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSevyqlGDVSQKTTWHRISVFRPgLRDVAYQYVKKGSRI 108
Cdd:PRK06958   3 SVNKVILVGNLGADPEVRYLPSGDAVANIRLATTDRYKDKAS-----GEFKEATEWHRVAFFGR-LAEIVGEYLKKGSSV 76

                         90       100       110
                 ....*....|....*....|....*....|..
gi 374671785 109 YLEGKIDYGEYMDKNNVRRQATTIIADNIIFL 140
Cdd:PRK06958  77 YIEGRIRTRKWQGQDGQDRYSTEIVADQMQML 108
PRK06863 PRK06863
single-stranded DNA-binding protein; Provisional
 30-135 8.68e-16

single-stranded DNA-binding protein; Provisional


Pssm-ID: 136097 [Multi-domain]  Cd Length: 168  Bit Score: 70.00  E-value: 8.68e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  30 LNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSevyqlGDVSQKTTWHRIsVFRPGLRDVAYQYVKKGSRIY 109
Cdd:PRK06863   4 INKVIIVGHLGNDPEIRTMPNGEAVANISVATSESWTDKNT-----GERREVTEWHRI-VFYRRQAEVAGEYLRKGSQVY 77

                         90       100
                 ....*....|....*....|....*.
gi 374671785 110 LEGKIDYGEYMDKNNVRRQATTIIAD 135
Cdd:PRK06863  78 VEGRLKTRKWQDQNGQDRYTTEIQGD 103
PRK08486 PRK08486
single-stranded DNA-binding protein; Provisional
 31-144 2.03e-09

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236275 [Multi-domain]  Cd Length: 182  Bit Score: 53.31  E-value: 2.03e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  31 NRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDsevyqlGDVSQKTTWHRISVF-RPGlrDVAYQYVKKGSRIY 109
Cdd:PRK08486   3 NKVILVGNLTRDVELRYLPSGSAIATIGLATSRRFKKQD------GEKGEEVCFIDIRLFgRTA--EIANQYLSKGSKVL 74

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 374671785 110 LEGKIDYGEYMDKNNVRRQATTIIADNIIFLSDQT 144
Cdd:PRK08486  75 IEGRLTFESWMDQNGQKRSKHTITAESMQMLDSKS 109
PRK07459 PRK07459
single-stranded DNA-binding protein; Provisional
 29-141 5.88e-09

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180986  Cd Length: 121  Bit Score: 50.84  E-value: 5.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  29 SLNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEmwRSGDSEvyqlGDVSQKTTWHRISvfrpglrDVAYQYVKKGSRI 108
Cdd:PRK07459   2 SLNSVTLVGRAGRDPEVRYFESGSVVCNLTLAVNR--RSRDDE----PDWFNLEIWGKTA-------QVAADYVKKGSLI 68

                         90       100       110
                 ....*....|....*....|....*....|....
gi 374671785 109 YLEGKIDYGEYMDKNN-VRRQATTIIADNIIFLS 141
Cdd:PRK07459  69 GITGSLKFDRWTDRNTgEDRSKPVIRVDRLELLG 102
PRK06293 PRK06293
single-stranded DNA-binding protein; Provisional
 30-139 6.74e-09

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180517 [Multi-domain]  Cd Length: 161  Bit Score: 51.44  E-value: 6.74e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  30 LNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEmwRSGDSEvyqlgdvsqKTTWHRISVFrpGLR-DVAYQYVKKGSRI 108
Cdd:PRK06293   1 MMFGYIVGRLGADPEERMTSKGKRVVVLRLGVKS--RVGSKD---------ETVWCRCNIW--GNRyDKMLPYLKKGSGV 67

                         90       100       110
                 ....*....|....*....|....*....|.
gi 374671785 109 YLEGKIDYGEYMDKNNVRRQATTIIADNIIF 139
Cdd:PRK06293  68 IVAGEMSPESYVDKDGSPQSSLVVSVDTIKF 98
PRK06751 PRK06751
single-stranded DNA-binding protein; Provisional
 30-140 6.28e-07

single-stranded DNA-binding protein; Provisional


Pssm-ID: 168659 [Multi-domain]  Cd Length: 173  Bit Score: 46.33  E-value: 6.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  30 LNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSEvyqlgdvsQKTTWHRISVFRPGLRDVAyQYVKKGSRIY 109
Cdd:PRK06751   2 MNRVILVGRLTKDPDLRYTPNGVAVATFTLAVNRAFANQQGE--------READFINCVIWRKQAENVA-NYLKKGSLAG 72

                         90       100       110
                 ....*....|....*....|....*....|.
gi 374671785 110 LEGKIDYGEYMDKNNVRRQATTIIADNIIFL 140
Cdd:PRK06751  73 VDGRLQTRNYEGQDGKRVYVTEVLAESVQFL 103
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
 30-146 7.99e-06

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 43.34  E-value: 7.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  30 LNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSGDSEvyqlgdvsQKTTWHRISVFRPGLRDVAyQYVKKGSRIY 109
Cdd:PRK07275   2 INNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGE--------READFINCVIWRQQAENLA-NWAKKGALIG 72

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 374671785 110 LEGKIDYGEYMDKNNVRRQATTIIADNIIFL-SDQTKE 146
Cdd:PRK07275  73 VTGRIQTRNYENQQGQRVYVTEVVADNFQMLeSRATRE 110
PRK06752 PRK06752
single-stranded DNA-binding protein; Validated
 30-140 6.93e-05

single-stranded DNA-binding protein; Validated


Pssm-ID: 168660  Cd Length: 112  Bit Score: 40.02  E-value: 6.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 374671785  30 LNRVHLLGRVGQDPVLRQVEGKNPVTIFSLATNEMWRSgdsevyQLGDvsQKTTWHRISVFRPGLRDVAyQYVKKGSRIY 109
Cdd:PRK06752   2 MNRVVLIGRLTKEPELYYTKQGVAYARVCVAVNRGFRN------SLGE--QQVDFINCVVWRKSAENVT-EYCTKGSLVG 72

                         90       100       110
                 ....*....|....*....|....*....|.
gi 374671785 110 LEGKIDYGEYMDKNNVRRQATTIIADNIIFL 140
Cdd:PRK06752  73 ITGRIHTRNYEDDQGKRIYITEVVIESITFL 103
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH