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metalloreductase STEAP2 isoform c [Homo sapiens]
COG2085 and Ferric_reduct domain-containing protein( domain architecture ID 11946522)
COG2085 and Ferric_reduct domain-containing protein
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||
COG2085 | COG2085 | Predicted dinucleotide-binding enzyme [General function prediction only]; |
33-222 | 1.09e-36 | ||||
Predicted dinucleotide-binding enzyme [General function prediction only]; : Pssm-ID: 441688 [Multi-domain] Cd Length: 205 Bit Score: 132.99 E-value: 1.09e-36
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Ferric_reduct | pfam01794 | Ferric reductase like transmembrane component; This family includes a common region in the ... |
259-401 | 1.07e-07 | ||||
Ferric reductase like transmembrane component; This family includes a common region in the transmembrane proteins mammalian cytochrome B-245 heavy chain (gp91-phox), ferric reductase transmembrane component in yeast and respiratory burst oxidase from mouse-ear cress. This may be a family of flavocytochromes capable of moving electrons across the plasma membrane. The Frp1 protein from S. pombe is a ferric reductase component and is required for cell surface ferric reductase activity, mutants in frp1 are deficient in ferric iron uptake. Cytochrome B-245 heavy chain is a FAD-dependent dehydrogenase it is also has electron transferase activity which reduces molecular oxygen to superoxide anion, a precursor in the production of microbicidal oxidants. Mutations in the sequence of cytochrome B-245 heavy chain (gp91-phox) lead to the X-linked chronic granulomatous disease. The bacteriocidal ability of phagocytic cells is reduced and is characterized by the absence of a functional plasma membrane associated NADPH oxidase. The chronic granulomatous disease gene codes for the beta chain of cytochrome B-245 and cytochrome B-245 is missing from patients with the disease. : Pssm-ID: 426438 [Multi-domain] Cd Length: 121 Bit Score: 50.34 E-value: 1.07e-07
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Name | Accession | Description | Interval | E-value | ||||
COG2085 | COG2085 | Predicted dinucleotide-binding enzyme [General function prediction only]; |
33-222 | 1.09e-36 | ||||
Predicted dinucleotide-binding enzyme [General function prediction only]; Pssm-ID: 441688 [Multi-domain] Cd Length: 205 Bit Score: 132.99 E-value: 1.09e-36
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F420_oxidored | pfam03807 | NADP oxidoreductase coenzyme F420-dependent; |
34-119 | 4.60e-20 | ||||
NADP oxidoreductase coenzyme F420-dependent; Pssm-ID: 397743 [Multi-domain] Cd Length: 92 Bit Score: 84.21 E-value: 4.60e-20
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Ferric_reduct | pfam01794 | Ferric reductase like transmembrane component; This family includes a common region in the ... |
259-401 | 1.07e-07 | ||||
Ferric reductase like transmembrane component; This family includes a common region in the transmembrane proteins mammalian cytochrome B-245 heavy chain (gp91-phox), ferric reductase transmembrane component in yeast and respiratory burst oxidase from mouse-ear cress. This may be a family of flavocytochromes capable of moving electrons across the plasma membrane. The Frp1 protein from S. pombe is a ferric reductase component and is required for cell surface ferric reductase activity, mutants in frp1 are deficient in ferric iron uptake. Cytochrome B-245 heavy chain is a FAD-dependent dehydrogenase it is also has electron transferase activity which reduces molecular oxygen to superoxide anion, a precursor in the production of microbicidal oxidants. Mutations in the sequence of cytochrome B-245 heavy chain (gp91-phox) lead to the X-linked chronic granulomatous disease. The bacteriocidal ability of phagocytic cells is reduced and is characterized by the absence of a functional plasma membrane associated NADPH oxidase. The chronic granulomatous disease gene codes for the beta chain of cytochrome B-245 and cytochrome B-245 is missing from patients with the disease. Pssm-ID: 426438 [Multi-domain] Cd Length: 121 Bit Score: 50.34 E-value: 1.07e-07
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Name | Accession | Description | Interval | E-value | ||||
COG2085 | COG2085 | Predicted dinucleotide-binding enzyme [General function prediction only]; |
33-222 | 1.09e-36 | ||||
Predicted dinucleotide-binding enzyme [General function prediction only]; Pssm-ID: 441688 [Multi-domain] Cd Length: 205 Bit Score: 132.99 E-value: 1.09e-36
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F420_oxidored | pfam03807 | NADP oxidoreductase coenzyme F420-dependent; |
34-119 | 4.60e-20 | ||||
NADP oxidoreductase coenzyme F420-dependent; Pssm-ID: 397743 [Multi-domain] Cd Length: 92 Bit Score: 84.21 E-value: 4.60e-20
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Ferric_reduct | pfam01794 | Ferric reductase like transmembrane component; This family includes a common region in the ... |
259-401 | 1.07e-07 | ||||
Ferric reductase like transmembrane component; This family includes a common region in the transmembrane proteins mammalian cytochrome B-245 heavy chain (gp91-phox), ferric reductase transmembrane component in yeast and respiratory burst oxidase from mouse-ear cress. This may be a family of flavocytochromes capable of moving electrons across the plasma membrane. The Frp1 protein from S. pombe is a ferric reductase component and is required for cell surface ferric reductase activity, mutants in frp1 are deficient in ferric iron uptake. Cytochrome B-245 heavy chain is a FAD-dependent dehydrogenase it is also has electron transferase activity which reduces molecular oxygen to superoxide anion, a precursor in the production of microbicidal oxidants. Mutations in the sequence of cytochrome B-245 heavy chain (gp91-phox) lead to the X-linked chronic granulomatous disease. The bacteriocidal ability of phagocytic cells is reduced and is characterized by the absence of a functional plasma membrane associated NADPH oxidase. The chronic granulomatous disease gene codes for the beta chain of cytochrome B-245 and cytochrome B-245 is missing from patients with the disease. Pssm-ID: 426438 [Multi-domain] Cd Length: 121 Bit Score: 50.34 E-value: 1.07e-07
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Blast search parameters | ||||
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