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Conserved domains on  [gi|343790880|ref|NP_001230494|]
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dehydrodolichyl diphosphate synthase complex subunit DHDDS isoform 4 [Homo sapiens]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10087541)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates

CATH:  3.40.1180.10
EC:  2.5.1.-
Gene Ontology:  GO:0004659|GO:0016094
PubMed:  16900467|12636086|12135472
SCOP:  4003318

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 28-209 9.17e-98

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


:

Pssm-ID: 259850  Cd Length: 219  Bit Score: 286.58  E-value: 9.17e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEE 107
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 108 ------------------------------------KCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLDK 151
Cdd:cd00475   81 lhkngvrlrvigdlsllpedlreaieeaeeatknntGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 343790880 152 CLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:cd00475  161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
 
Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 28-209 9.17e-98

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 286.58  E-value: 9.17e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEE 107
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 108 ------------------------------------KCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLDK 151
Cdd:cd00475   81 lhkngvrlrvigdlsllpedlreaieeaeeatknntGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 343790880 152 CLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:cd00475  161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 32-212 3.46e-85

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 254.60  E-value: 3.46e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880   32 IMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKF-----SRLME 106
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEYlrrelPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  107 E--------------------------------KCFLNVCFAYTSRHEISNAVREMAwgVEQGLLDPSDISESLLDKCLY 154
Cdd:pfam01255  81 NgvrvrvigdlsllpedlqeaieeaeeatknntGLTLNIALNYGGRDEIVDAVRKIV--KEGKKLDPEDIDEELISSHLY 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 343790880  155 TNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNH 212
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRE 216
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
20-209 4.51e-79

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 239.96  E-value: 4.51e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:COG0020   10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 100 KFSR----LMEE--------------------------------KCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSD 143
Cdd:COG0020   90 YLRReldeLHKNnvrvrvigdrsrlpeslqeaieeaeeltknntGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPED 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 343790880 144 ISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:COG0020  170 IDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQ 235
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 27-213 2.43e-68

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 211.88  E-value: 2.43e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880   27 KHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQK------ 100
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKldrevk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  101 -----------------FSRLMEEKC-------------FLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLD 150
Cdd:TIGR00055  81 elhrynvririigdlslLSKELQEKIkkaeedtknntdfTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 343790880  151 KCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNHS 213
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHR 223
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 20-209 3.18e-61

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 194.71  E-value: 3.18e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14830  17 LDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 100 KFS----RLME---------------EKCF-----------------LNVCFAYTSRHEISNAVREMAWGVEQGLLDPSD 143
Cdd:PRK14830  97 FLDkfvpELIEnnvkvnvigdtdrlpEHTLralekaiektknntgliLNFALNYGGRAEIVSAVKEIAKDVLDGKLNPED 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 343790880 144 ISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:PRK14830 177 ITEELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQ 242
 
Name Accession Description Interval E-value
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 28-209 9.17e-98

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 286.58  E-value: 9.17e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLMEE 107
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELEE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 108 ------------------------------------KCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLDK 151
Cdd:cd00475   81 lhkngvrlrvigdlsllpedlreaieeaeeatknntGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDPEDITEELISK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 343790880 152 CLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:cd00475  161 HLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQ 218
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 32-212 3.46e-85

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 254.60  E-value: 3.46e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880   32 IMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKF-----SRLME 106
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELLKEEYlrrelPELHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  107 E--------------------------------KCFLNVCFAYTSRHEISNAVREMAwgVEQGLLDPSDISESLLDKCLY 154
Cdd:pfam01255  81 NgvrvrvigdlsllpedlqeaieeaeeatknntGLTLNIALNYGGRDEIVDAVRKIV--KEGKKLDPEDIDEELISSHLY 158

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 343790880  155 TNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNH 212
Cdd:pfam01255 159 TAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRE 216
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
20-209 4.51e-79

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 239.96  E-value: 4.51e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:COG0020   10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 100 KFSR----LMEE--------------------------------KCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSD 143
Cdd:COG0020   90 YLRReldeLHKNnvrvrvigdrsrlpeslqeaieeaeeltknntGLTLNIALNYGGRWEIVDAVRKIARDVAAGELDPED 169

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 343790880 144 ISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:COG0020  170 IDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQ 235
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 27-213 2.43e-68

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 211.88  E-value: 2.43e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880   27 KHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQK------ 100
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKldrevk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  101 -----------------FSRLMEEKC-------------FLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLD 150
Cdd:TIGR00055  81 elhrynvririigdlslLSKELQEKIkkaeedtknntdfTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLPEDIDEETLN 160

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 343790880  151 KCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMNHS 213
Cdd:TIGR00055 161 KHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHR 223
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 20-209 3.18e-61

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 194.71  E-value: 3.18e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14830  17 LDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 100 KFS----RLME---------------EKCF-----------------LNVCFAYTSRHEISNAVREMAWGVEQGLLDPSD 143
Cdd:PRK14830  97 FLDkfvpELIEnnvkvnvigdtdrlpEHTLralekaiektknntgliLNFALNYGGRAEIVSAVKEIAKDVLDGKLNPED 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 343790880 144 ISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:PRK14830 177 ITEELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQ 242
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 25-209 1.00e-54

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 177.83  E-value: 1.00e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDL----ARQK 100
Cdd:PRK14831  20 LPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLfervLRRE 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 101 FSRLMEEKC---FL-----------------------------NVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESL 148
Cdd:PRK14831 100 LEELMEENVrirFVgdldplpkslqeeisrsteltknnngihfNVCTNYGGRQEIVQAARAIAQQVQQGELDPSEIDENL 179

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 343790880 149 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:PRK14831 180 FESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQ 240
PRK14834 PRK14834
isoprenyl transferase;
26-208 2.92e-48

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 161.07  E-value: 2.92e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  26 PKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARqKFSR-- 103
Cdd:PRK14834  15 PRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLR-LFIRrd 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 104 --------------------------LMEE---------KCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESL 148
Cdd:PRK14834  94 laelhrngvrvrvigeragleadicaLLNEaeeltrnntGLNLVIAFNYGSRDEIARAVRRLAREVAEGRLDPASIDAET 173

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 149 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 208
Cdd:PRK14834 174 ISANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEY 233
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 25-210 1.44e-47

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 159.78  E-value: 1.44e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLM----DLARQK 100
Cdd:PRK14832  18 IPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMllfeRLLRRE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 101 FSRLMEE--------------------------------KCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESL 148
Cdd:PRK14832  98 LAQMHREgvrisfigdlsalpkslqtemersmtetlnnqAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADAVNEQL 177

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 343790880 149 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQM 210
Cdd:PRK14832 178 VEQHLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQK 239
PRK14835 PRK14835
isoprenyl transferase;
11-209 1.95e-46

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 157.31  E-value: 1.95e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  11 LWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEV 90
Cdd:PRK14835  27 GYEQRLEREVKHGKLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEV 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  91 DGLMDLARQKFSRL--------------------------------MEEKC------FLNVCFAYTSRHEISNAVREMAW 132
Cdd:PRK14835 107 ETLMNLFEREARRMavdprihanrvrvraigrhdgfppkvlealeeLEERTeghegmLLNIAVGYGGREEIVDAVKSLLL 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 133 GVEQGLLDPSDISESL----LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 208
Cdd:PRK14835 187 EAAATGKSPEEVAAELtpehISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDY 266


                 .
gi 343790880 209 Q 209
Cdd:PRK14835 267 Q 267
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 19-228 1.17e-43

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 149.45  E-value: 1.17e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  19 IIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDL-- 96
Cdd:PRK14836   8 IPANENIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELfl 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  97 ---------------------ARQKFS-RLME------------EKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPS 142
Cdd:PRK14836  88 kaldrevdklhrngirvrfigDRSRLSpKLQErmeyaerltasnTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAPD 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 143 DISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYtfwnlfeailqfqmNHSVLQKARDMY 222
Cdd:PRK14836 168 EIDEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDF--------------DAQELQQALEDY 233


                 ....*.
gi 343790880 223 AEERKR 228
Cdd:PRK14836 234 ASRERR 239
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 20-208 1.30e-40

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 141.07  E-value: 1.30e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14829   9 IPKNKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 100 KFSR---LMEEKCF---------------------------------LNVCFAYTSRHEISNAVREMAWGVEQGLLDPSD 143
Cdd:PRK14829  89 VIHRrreQMDEWGVrvrwsgrrprlwksvideleaaeeltknnttmdLVFCVNYGGRAEIADAAAAIAREVRDGKISGDR 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 343790880 144 ISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 208
Cdd:PRK14829 169 VTEKMISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEY 233
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
25-208 5.84e-39

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 136.48  E-value: 5.84e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLAR------ 98
Cdd:PRK14833   4 TLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKkylkde 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  99 -----------------QKFSR-------LMEEKCF----LNVCFA--YTSRHEISNAVREM--AWGVEQGLLdpsDISE 146
Cdd:PRK14833  84 rstylennirfkaigdlEGFSKelrdtilQLEEDTRsfkgFTQVLAlnYGSKDEISRAFKKLleSPPSHIGEL---ESLE 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 343790880 147 SLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQF 208
Cdd:PRK14833 161 EEISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDF 222
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 11-212 2.30e-38

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 135.64  E-value: 2.30e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  11 LWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVER-QEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSE 89
Cdd:PRK14828  12 VYARRLLGELDGAQVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEE 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  90 VDGLMDLARQKFSRLMEEK------------------CFL---------------NVCFAYTSRHEISNAVREMAW-GVE 135
Cdd:PRK14828  92 LNPLLDIIEDVVRQLAPDGrwrvrhvgsldllpapsaNRLkeaeeatvgndgikvNVAVGYGGRQEIVDAVRSLLTeHKD 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 136 QGLlDPSDISES----LLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQMN 211
Cdd:PRK14828 172 KGT-SIDELAESvtvdAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALRDYSQR 250


                 .
gi 343790880 212 H 212
Cdd:PRK14828 251 E 251
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 24-209 3.10e-38

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 135.36  E-value: 3.10e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  24 PMPKHIAFIMDGNRRYAKK----CQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDL--- 96
Cdd:PRK14840  17 SLPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAELFSLfns 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  97 -ARQKFSRLMEEK----CF--------------------------LNVCFA--YTSRHEISNAVREMAWGVEQGLLDPSD 143
Cdd:PRK14840  97 qLDSQLPYLHENEirlrCIgdlsklpqelqnnieqassatahysrMELVLAinYGGKDELVRAFKKLHQDLANKKISSDD 176

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 343790880 144 ISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:PRK14840 177 ISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQ 242
PRK14838 PRK14838
isoprenyl transferase;
25-209 3.94e-38

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 134.62  E-value: 3.94e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDL-------- 96
Cdd:PRK14838  10 IPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLlldsieee 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  97 ---------------------ARQKFSRLMEEKCF-----LNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLD 150
Cdd:PRK14838  90 tfmknnirfriigdiaklpeeVQERLNECEEHTAKntgmcLVLALSYSSRWEITEATRQIATLVQNGELNPEEITEESIS 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 343790880 151 KCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:PRK14838 170 EHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQ 228
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 25-205 1.56e-37

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 132.81  E-value: 1.56e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRL 104
Cdd:PRK14841   3 IPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIDRE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 105 ME------------------------------------EKCFLNVCFAYTSRHEISNAVREMAWGVEQGllDPSDISESL 148
Cdd:PRK14841  83 MEllrrervrvrilgrkeglpekvlkkwqeveektkefDRMTLVIAFNYGGRREILDAVESILKDVSQG--KKIELTEET 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 343790880 149 LDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAI 205
Cdd:PRK14841 161 FRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAI 217
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 20-204 5.32e-37

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 133.16  E-value: 5.32e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  20 IKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQ 99
Cdd:PRK14827  62 IPADRLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFNRD 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 100 KFSRLME------------------------------------EKCFLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSD 143
Cdd:PRK14827 142 VVRRRRDnlnkmgvrirwvgsrprlwrsvinelaiaeemtksnDVITINYCVNYGGRTEITEATREIAREAAAGRLNPER 221

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 343790880 144 ISESLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEA 204
Cdd:PRK14827 222 ITESTIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAA 282
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 25-209 4.87e-34

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 123.94  E-value: 4.87e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  25 MPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDL-------- 96
Cdd:PRK14842   8 IPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLlvefietr 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  97 ---------------ARQKFSRLMEEKC-------------FLNVCFAYTSRHEI-SNAVREMAWGVEQGLLDPSDISES 147
Cdd:PRK14842  88 ldtihargirihhsgSRKKLTRTVLDKIdfamaktkknknlTVNFCLNYGSHDELlRAAQEVFLARKAKKVTLEKPLKEK 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 343790880 148 LLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:PRK14842 168 EFEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYE 229
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
33-219 4.56e-29

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 110.46  E-value: 4.56e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  33 MDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDL---------------- 96
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELfvwaldsevkslhrhn 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  97 -------ARQKFSRLMEEKC-------------FLNVCFAYTSRHEISNAVREMAWGVEQGLLDPSDISESLLDKCLYTN 156
Cdd:PRK10240  81 vrlriigDTSRFNSRLQERIrksealtagntglTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQPDQIDEEMLNQHICMH 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 343790880 157 RSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTfWNLFEAILqfqmnHSVLQKAR 219
Cdd:PRK10240 161 ELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFD-EQDFEGAL-----NAFANRER 217
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 23-196 2.82e-28

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 108.37  E-value: 2.82e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  23 GPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLM----DLAR 98
Cdd:PRK14837   4 NSLPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMfliaDYLS 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  99 QKFS----------------RLMEE------------KCF----LNVCFAYTSRHEISNAVREMawgVEQGlLDPSDISE 146
Cdd:PRK14837  84 SEFNfykknnikiivsgdieSLSEEvkksikdaisftKNFdglvLNLAINYGGRNEIVRAVKKF---LSSG-LDLETLNE 159

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 343790880 147 SLLDKCLYTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEY 196
Cdd:PRK14837 160 NVFSKFLDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEY 209
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
28-209 2.60e-25

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 100.99  E-value: 2.60e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  28 HIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKSEVDGLMDLARQKFSRLME- 106
Cdd:PRK14839  12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAYLRNETEr 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 107 -----------------------------------EKCFLNVCFAYTSRHEISNAVREMawgveqglLDPSDISESLLDK 151
Cdd:PRK14839  92 larngvrltvigrrdrlpdgipeaiaraeaataggDRLHLRIAVDYSARDAILAAAAKA--------LGPEGLSREAFSD 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 343790880 152 CLyTNRSPHPDILIRTSGEVRLSDFLLWQTSHSCLVFQPVLWPEYTFWNLFEAILQFQ 209
Cdd:PRK14839 164 LL-TGDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFH 220
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 9-210 3.52e-21

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 91.21  E-value: 3.52e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880   9 LSLWERFCANIIKAGPMPKHIAFIMDGNRRYAKKCQVERQEGHSQGFNKLAETLRWCLNLGILEVTVYAFSIENFKRSKS 88
Cdd:PTZ00349   3 LNIIERFITSLLRDFINIKHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880  89 EV--------------DGLMDLARQKFSRL-------------------MEEKC------FLNVCFAYTSRHEIS----- 124
Cdd:PTZ00349  83 EIhflfylnllilineDFFFKFIKDNKIKIkiignlsyindayrkiihdIEEKTenfdniLLNIFFSYTSRNEMSlckfn 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 343790880 125 ---------NAVRE---------MAWGVEQGLLDPSDISESL-------------LD-----KC---------------- 152
Cdd:PTZ00349 163 pnlyfdtykNLLEEkkilcgsniLTDPIKEGTFAIPDDEDECdyldheleneridLDlkfdgDCicgeksflneeqieiv 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 343790880 153 -----LYTNRSPHPDILIRTSGEVRLSDFLLWQTSH-SCLVFQPVLWPEYTFWNLFEAILQFQM 210
Cdd:PTZ00349 243 nyhkkLLTSDLPPPNILIRTSGEKRLSDFMLYQISEfTEIYFINEYWPIFNFLQFIYIILHYTI 306
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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