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Conserved domains on  [gi|334187226|ref|NP_001190938|]
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Integrase-type DNA-binding superfamily protein [Arabidopsis thaliana]

Protein Classification

AP2/ERF family transcription factor( domain architecture ID 10889857)

AP2/ERF family transcription factor binds to the GCC-box pathogenesis-related promoter element; similar to Oryza sativa APETALA2-like proteins which act as transcription factors

CATH:  3.30.730.10
Gene Ontology:  GO:0003700|GO:0006355|GO:0003677
PubMed:  15708341
SCOP:  4000937

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
223-286 1.84e-28

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


:

Pssm-ID: 197689  Cd Length: 64  Bit Score: 106.58  E-value: 1.84e-28
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334187226   223 KYRGVTLHKCGRWEARMGQFLGKKYVYLGLFDTEVEAARAYDKAAIKCNGKDAVTNFDPSIYDE 286
Cdd:smart00380   1 KYRGVRQRPWGKWVAEIRDPSKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLYDS 64
AP2 super family cl00033
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
 131-192 1.33e-13

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


The actual alignment was detected with superfamily member smart00380:

Pssm-ID: 444663  Cd Length: 64  Bit Score: 65.36  E-value: 1.33e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334187226   131 QYRGVTFyRRTGRWESHIWD--CGKQVYLGGFDTAHAAARAYDRAAIKFRGVEADINFNIDDYD 192
Cdd:smart00380   1 KYRGVRQ-RPWGKWVAEIRDpsKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLYD 63
 
Name Accession Description Interval E-value
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
223-286 1.84e-28

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 106.58  E-value: 1.84e-28
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334187226   223 KYRGVTLHKCGRWEARMGQFLGKKYVYLGLFDTEVEAARAYDKAAIKCNGKDAVTNFDPSIYDE 286
Cdd:smart00380   1 KYRGVRQRPWGKWVAEIRDPSKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLYDS 64
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
 222-282 2.11e-25

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 98.11  E-value: 2.11e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334187226 222 SKYRGVTLHKCGRWEARMGQFLGKKYVYLGLFDTEVEAARAYDKAAIKCNGKDAVTNFDPS 282
Cdd:cd00018    1 SKYRGVRQRPWGKWVAEIRDPSGGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFPDS 61
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
131-192 1.33e-13

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 65.36  E-value: 1.33e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334187226   131 QYRGVTFyRRTGRWESHIWD--CGKQVYLGGFDTAHAAARAYDRAAIKFRGVEADINFNIDDYD 192
Cdd:smart00380   1 KYRGVRQ-RPWGKWVAEIRDpsKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLYD 63
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
 131-189 2.25e-11

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 58.82  E-value: 2.25e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334187226 131 QYRGVTFyRRTGRWESHIWDC--GKQVYLGGFDTAHAAARAYDRAAIKFRGVEADINFNID 189
Cdd:cd00018    2 KYRGVRQ-RPWGKWVAEIRDPsgGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFPDS 61
AP2 pfam00847
AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription ...
 223-269 6.59e-07

AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription factor proteins.


Pssm-ID: 425904  Cd Length: 52  Bit Score: 46.09  E-value: 6.59e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 334187226  223 KYRGVTLHKC-GRWEA--RMGQFLGKKYVYLGLFDTEvEAARAYDKAAIK 269
Cdd:pfam00847   1 KIRGVRYDKKwGRWVAewSENGKRRKKRFSLGKYGTE-EAKRAAIEARKK 49
 
Name Accession Description Interval E-value
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
223-286 1.84e-28

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 106.58  E-value: 1.84e-28
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334187226   223 KYRGVTLHKCGRWEARMGQFLGKKYVYLGLFDTEVEAARAYDKAAIKCNGKDAVTNFDPSIYDE 286
Cdd:smart00380   1 KYRGVRQRPWGKWVAEIRDPSKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLYDS 64
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
 222-282 2.11e-25

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 98.11  E-value: 2.11e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334187226 222 SKYRGVTLHKCGRWEARMGQFLGKKYVYLGLFDTEVEAARAYDKAAIKCNGKDAVTNFDPS 282
Cdd:cd00018    1 SKYRGVRQRPWGKWVAEIRDPSGGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFPDS 61
AP2 smart00380
DNA-binding domain in plant proteins such as APETALA2 and EREBPs;
131-192 1.33e-13

DNA-binding domain in plant proteins such as APETALA2 and EREBPs;


Pssm-ID: 197689  Cd Length: 64  Bit Score: 65.36  E-value: 1.33e-13
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 334187226   131 QYRGVTFyRRTGRWESHIWD--CGKQVYLGGFDTAHAAARAYDRAAIKFRGVEADINFNIDDYD 192
Cdd:smart00380   1 KYRGVRQ-RPWGKWVAEIRDpsKGKRVWLGTFDTAEEAARAYDRAAFKFRGRSARLNFPNSLYD 63
AP2 cd00018
DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP ...
 131-189 2.25e-11

DNA-binding domain found in transcription regulators in plants such as APETALA2 and EREBP (ethylene responsive element binding protein). In EREBPs the domain specifically binds to the 11bp GCC box of the ethylene response element (ERE), a promotor element essential for ethylene responsiveness. EREBPs and the C-repeat binding factor CBF1, which is involved in stress response, contain a single copy of the AP2 domain. APETALA2-like proteins, which play a role in plant development contain two copies.


Pssm-ID: 237985  Cd Length: 61  Bit Score: 58.82  E-value: 2.25e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 334187226 131 QYRGVTFyRRTGRWESHIWDC--GKQVYLGGFDTAHAAARAYDRAAIKFRGVEADINFNID 189
Cdd:cd00018    2 KYRGVRQ-RPWGKWVAEIRDPsgGRRIWLGTFDTAEEAARAYDRAALKLRGSSAVLNFPDS 61
AP2 pfam00847
AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription ...
 223-269 6.59e-07

AP2 domain; This 60 amino acid residue domain can bind to DNA and is found in transcription factor proteins.


Pssm-ID: 425904  Cd Length: 52  Bit Score: 46.09  E-value: 6.59e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 334187226  223 KYRGVTLHKC-GRWEA--RMGQFLGKKYVYLGLFDTEvEAARAYDKAAIK 269
Cdd:pfam00847   1 KIRGVRYDKKwGRWVAewSENGKRRKKRFSLGKYGTE-EAKRAAIEARKK 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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