|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
107-372 |
2.89e-23 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 102.70 E-value: 2.89e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 107 QLEKIYPEELSRLHRLETLNLQNNRLTSrgLPEkAFEHLTNLNYLYLANNKLTLAPRFLPNAlisvdfaanyltkiyglt 186
Cdd:COG4886 100 ELDLSGNEELSNLTNLESLDLSGNQLTD--LPE-ELANLTNLKELDLSNNQLTDLPEPLGNL------------------ 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 187 fgqkPNLRSVYLHNNKLADagLPDNMFNgSSNVEVLILSSNFLRHVPKHL--PPALYKLHLKNNKLEKIPPgAFSELSSL 264
Cdd:COG4886 159 ----TNLKSLDLSNNQLTD--LPEELGN-LTNLKELDLSNNQITDLPEPLgnLTNLEELDLSGNQLTDLPE-PLANLTNL 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 265 RELYLQNNYLTdeglDNETFWKLSSLEYLDLSSNNLSRVPAGLP-RSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSN 343
Cdd:COG4886 231 ETLDLSNNQLT----DLPELGNLTNLEELDLSNNQLTDLPPLANlTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLL 306
|
250 260
....*....|....*....|....*....
gi 1719757105 344 QLREQGIHPLAFQGLKRLHTVHLYNNALE 372
Cdd:COG4886 307 LLNLLELLILLLLLTTLLLLLLLLKGLLV 335
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
101-375 |
1.63e-22 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 100.39 E-value: 1.63e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 101 LSLQNNQLEKIyPEELSRLHRLETLNLQNNRLTSrgLPEkAFEHLTNLNYLYLANNKLTLAPRFLPN--ALISVDFAANY 178
Cdd:COG4886 118 LDLSGNQLTDL-PEELANLTNLKELDLSNNQLTD--LPE-PLGNLTNLKSLDLSNNQLTDLPEELGNltNLKELDLSNNQ 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 179 LTKIyGLTFGQKPNLRSVYLHNNKLADagLPDNMFNgSSNVEVLILSSNFLRHVP--KHLpPALYKLHLKNNKLEKIPPG 256
Cdd:COG4886 194 ITDL-PEPLGNLTNLEELDLSGNQLTD--LPEPLAN-LTNLETLDLSNNQLTDLPelGNL-TNLEELDLSNNQLTDLPPL 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 257 AfsELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLE 336
Cdd:COG4886 269 A--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSL 346
|
250 260 270
....*....|....*....|....*....|....*....
gi 1719757105 337 YLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVP 375
Cdd:COG4886 347 LALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALL 385
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
55-308 |
1.93e-21 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 99.00 E-value: 1.93e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 55 SPEEPGPG-PAAVSCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIyPEELSRlhRLETLNLQNNRLT 133
Cdd:PRK15370 157 APAKEAANrEEAVQRMRDCLKNNKTELRLKILGLTTIPACIPEQITTLILDNNELKSL-PENLQG--NIKTLYANSNQLT 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 134 SrgLPEKAFEHLTNLNylyLANNKLTLAPRFLPNALISVDFAANYLTKIYGlTFGQKPNLRSVYLHNNKLADAGLPD--- 210
Cdd:PRK15370 234 S--IPATLPDTIQEME---LSINRITELPERLPSALQSLDLFHNKISCLPE-NLPEELRYLSVYDNSIRTLPAHLPSgit 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 211 --NMFNGS---------SNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKL----EKIPPgafselsSLRELYLQNNYLT 275
Cdd:PRK15370 308 hlNVQSNSltalpetlpPGLKTLEAGENALTSLPASLPPELQVLDVSKNQItvlpETLPP-------TITTLDVSRNALT 380
|
250 260 270
....*....|....*....|....*....|....*
gi 1719757105 276 D--EGLDnetfwklSSLEYLDLSSNNLSRVPAGLP 308
Cdd:PRK15370 381 NlpENLP-------AALQIMQASRNNLVRLPESLP 408
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
98-372 |
1.51e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 94.23 E-value: 1.51e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 98 TNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAAN 177
Cdd:COG4886 20 LLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLT 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 178 YLTKIYGLTFGQKPNLRSVYLHNNKLADagLPDNMFNgSSNVEVLILSSNFLRHVPKHLP--PALYKLHLKNNKLEKIPP 255
Cdd:COG4886 100 ELDLSGNEELSNLTNLESLDLSGNQLTD--LPEELAN-LTNLKELDLSNNQLTDLPEPLGnlTNLKSLDLSNNQLTDLPE 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 256 gAFSELSSLRELYLQNNYLTDEGldnETFWKLSSLEYLDLSSNNLSRVPAGLPR--SLVLLHLEKNAIRSVDAnvLTPIR 333
Cdd:COG4886 177 -ELGNLTNLKELDLSNNQITDLP---EPLGNLTNLEELDLSGNQLTDLPEPLANltNLETLDLSNNQLTDLPE--LGNLT 250
|
250 260 270
....*....|....*....|....*....|....*....
gi 1719757105 334 SLEYLLLHSNQLREqgIHPLAfqGLKRLHTVHLYNNALE 372
Cdd:COG4886 251 NLEELDLSNNQLTD--LPPLA--NLTNLKTLDLSNNQLT 285
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
181-588 |
3.35e-19 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 92.22 E-value: 3.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 181 KIYGLTFgQKPNLRSVYLHNNKLAdAGLPDNMFNGSSNVEVLILSSN-FLRHVPKHLPPALYKLHLKNNKLEKIPPGAFS 259
Cdd:PLN00113 84 KISSAIF-RLPYIQTINLSNNQLS-GPIPDDIFTTSSSLRYLNLSNNnFTGSIPRGSIPNLETLDLSNNMLSGEIPNDIG 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 260 ELSSLRELYLQNNYLTdeGLDNETFWKLSSLEYLDLSSNNLS-RVPA--GLPRSLVLLHLEKNAIRS------------- 323
Cdd:PLN00113 162 SFSSLKVLDLGGNVLV--GKIPNSLTNLTSLEFLTLASNQLVgQIPRelGQMKSLKWIYLGYNNLSGeipyeiggltsln 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 324 ----VDANVLTPIRS-------LEYLLLHSNQLREQgIHPLAFqGLKRLHTVHLYNNALERVPSGLPRRVRTLMILH--- 389
Cdd:PLN00113 240 hldlVYNNLTGPIPSslgnlknLQYLFLYQNKLSGP-IPPSIF-SLQKLISLDLSDNSLSGEIPELVIQLQNLEILHlfs 317
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 390 NQITGIGREDFATTYFLEELNLSYNRItSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVK--RNELAALA 467
Cdd:PLN00113 318 NNFTGKIPVALTSLPRLQVLQLWSNKF-SGEIPKNLGKHNNLTVLDLSTNNLTGEIPEGLCSSGNLFKLIlfSNSLEGEI 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 468 RGALVGMAQLRELYLTSNRLRSRAlgPRAWVDLAHLQLLDIAGNQLT--------EIPeglpeSLEYLYLQNNKISAVPA 539
Cdd:PLN00113 397 PKSLGACRSLRRVRLQDNSFSGEL--PSEFTKLPLVYFLDISNNNLQgrinsrkwDMP-----SLQMLSLARNKFFGGLP 469
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 1719757105 540 NAFDSTpNLKGIFLRFNKLAvgSVVDSAFRRLKHLQVLDIEGNLEFGDI 588
Cdd:PLN00113 470 DSFGSK-RLENLDLSRNQFS--GAVPRKLGSLSELMQLKLSENKLSGEI 515
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
118-588 |
3.38e-19 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 92.22 E-value: 3.38e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 118 RLHRLETLNLQNNRLtSRGLPEKAFEHLTNLNYLYLANNKLTLA-PR-FLPNaLISVDFAANYLT-KIYgLTFGQKPNLR 194
Cdd:PLN00113 91 RLPYIQTINLSNNQL-SGPIPDDIFTTSSSLRYLNLSNNNFTGSiPRgSIPN-LETLDLSNNMLSgEIP-NDIGSFSSLK 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 195 SVYLHNNKLAdAGLPDNMFNGSSnVEVLILSSN-FLRHVPKHLPP--ALYKLHLKNNKLEKIPPGAFSELSSLRELYLQN 271
Cdd:PLN00113 168 VLDLGGNVLV-GKIPNSLTNLTS-LEFLTLASNqLVGQIPRELGQmkSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVY 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 272 NYLTdeGLDNETFWKLSSLEYLDLSSNNLS-RVPAGL--PRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLreQ 348
Cdd:PLN00113 246 NNLT--GPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIfsLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNF--T 321
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 349 GIHPLAFQGLKRLHTVHLYNNALE-RVPSGLPRR--VRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSpqvhrda 425
Cdd:PLN00113 322 GKIPVALTSLPRLQVLQLWSNKFSgEIPKNLGKHnnLTVLDLSTNNLTGEIPEGLCSSGNLFKLILFSNSLEG------- 394
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 426 frklrllrsldlsgnrlhTLPPGLP--RNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRaLGPRAWvDLAHL 503
Cdd:PLN00113 395 ------------------EIPKSLGacRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLQGR-INSRKW-DMPSL 454
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 504 QLLDIAGNQLTeipEGLPES-----LEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAvgSVVDSAFRRLKHLQVLD 578
Cdd:PLN00113 455 QMLSLARNKFF---GGLPDSfgskrLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLS--GEIPDELSSCKKLVSLD 529
|
490
....*....|
gi 1719757105 579 IEGNLEFGDI 588
Cdd:PLN00113 530 LSHNQLSGQI 539
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
106-417 |
6.32e-19 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 91.06 E-value: 6.32e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 106 NQLEKIYPEELSRLHRLETLNLQNNRLTsrGLPEKAFEHLTNLNYLYLANNKLT--LAPR-FLPNALISVDFAANYLTKI 182
Cdd:PLN00113 222 NNLSGEIPYEIGGLTSLNHLDLVYNNLT--GPIPSSLGNLKNLQYLFLYQNKLSgpIPPSiFSLQKLISLDLSDNSLSGE 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 183 YGLTFGQKPNLRSVYLHNNKL------ADAGLP--------DNMFNGS--------SNVEVLILSSNFLR-HVPKHLPPA 239
Cdd:PLN00113 300 IPELVIQLQNLEILHLFSNNFtgkipvALTSLPrlqvlqlwSNKFSGEipknlgkhNNLTVLDLSTNNLTgEIPEGLCSS 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 240 --LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEgLDNEtFWKLSSLEYLDLSSNNLS-RVPAG---LPrSLVL 313
Cdd:PLN00113 380 gnLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGE-LPSE-FTKLPLVYFLDISNNNLQgRINSRkwdMP-SLQM 456
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 314 LHLEKNairSVDANVLTPIRS--LEYLLLHSNQLreQGIHPLAFQGLKRLHTVHLYNNALE-RVPSGLP--RRVRTLMIL 388
Cdd:PLN00113 457 LSLARN---KFFGGLPDSFGSkrLENLDLSRNQF--SGAVPRKLGSLSELMQLKLSENKLSgEIPDELSscKKLVSLDLS 531
|
330 340
....*....|....*....|....*....
gi 1719757105 389 HNQITGIGREDFATTYFLEELNLSYNRIT 417
Cdd:PLN00113 532 HNQLSGQIPASFSEMPVLSQLDLSQNQLS 560
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
101-560 |
2.02e-16 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 83.36 E-value: 2.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 101 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTsrGLPEKAFEHLTNLNYLYLANNKLT-LAPRFL-------------- 165
Cdd:PLN00113 145 LDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLV--GKIPNSLTNLTSLEFLTLASNQLVgQIPRELgqmkslkwiylgyn 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 166 ------PN------ALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAgLPDNMFnGSSNVEVLILSSNFLR-HV 232
Cdd:PLN00113 223 nlsgeiPYeiggltSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGP-IPPSIF-SLQKLISLDLSDNSLSgEI 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 233 PKHLP--PALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNetFWKLSSLEYLDLSSNNLS-RVPAGLPR 309
Cdd:PLN00113 301 PELVIqlQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKN--LGKHNNLTVLDLSTNNLTgEIPEGLCS 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 310 S--LVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLreQGIHPLAFQGLKRLHTVHLYNNALE-RVPSG---LPrRVR 383
Cdd:PLN00113 379 SgnLFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSF--SGELPSEFTKLPLVYFLDISNNNLQgRINSRkwdMP-SLQ 455
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 384 TLMILHNQITGiGREDFATTYFLEELNLSYNRITSpqvhrdafrklrllrsldLSGNRLHTLPpglprNVHVLKVKRNEL 463
Cdd:PLN00113 456 MLSLARNKFFG-GLPDSFGSKRLENLDLSRNQFSG------------------AVPRKLGSLS-----ELMQLKLSENKL 511
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 464 AALARGALVGMAQLRELYLTSNRLRSRAlgPRAWVDLAHLQLLDIAGNQLT-EIPEGLP--ESLEYLYLQNNKISAvpan 540
Cdd:PLN00113 512 SGEIPDELSSCKKLVSLDLSHNQLSGQI--PASFSEMPVLSQLDLSQNQLSgEIPKNLGnvESLVQVNISHNHLHG---- 585
|
490 500
....*....|....*....|
gi 1719757105 541 afdSTPNlKGIFLRFNKLAV 560
Cdd:PLN00113 586 ---SLPS-TGAFLAINASAV 601
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
200-535 |
7.08e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 76.90 E-value: 7.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 200 NNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNyltdegl 279
Cdd:COG4886 34 LLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------- 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 280 dnETFWKLSSLEYLDLSSNNLSRVPAGLPR--SLVLLHLEKNAIRSVDAnVLTPIRSLEYLLLHSNQLREQgihPLAFQG 357
Cdd:COG4886 107 --EELSNLTNLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDL---PEELGN 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 358 LKRLHTVHLYNNALERVPSGLPRRVRtlmilhnqitgigredfattyfLEELNLSYNRITSpqvhrdafrklrllrsldl 437
Cdd:COG4886 181 LTNLKELDLSNNQITDLPEPLGNLTN----------------------LEELDLSGNQLTD------------------- 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 438 sgnrlhtLPPGLPRnvhvlkvkrnelaalargalvgMAQLRELYLTSNRLRS-RALGprawvDLAHLQLLDIAGNQLTEI 516
Cdd:COG4886 220 -------LPEPLAN----------------------LTNLETLDLSNNQLTDlPELG-----NLTNLEELDLSNNQLTDL 265
|
330 340
....*....|....*....|
gi 1719757105 517 PEGLP-ESLEYLYLQNNKIS 535
Cdd:COG4886 266 PPLANlTNLKTLDLSNNQLT 285
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
139-466 |
2.26e-14 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 76.66 E-value: 2.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 139 EKAFEHL-----TNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKiygLTFGQKPNLRSVYLHNNKLAD--AGLPDN 211
Cdd:PRK15370 166 EEAVQRMrdclkNNKTELRLKILGLTTIPACIPEQITTLILDNNELKS---LPENLQGNIKTLYANSNQLTSipATLPDT 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 212 mfngssnVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPpgafselsslrelylqnNYLTDEgldnetfwklssLE 291
Cdd:PRK15370 243 -------IQEMELSINRITELPERLPSALQSLDLFHNKISCLP-----------------ENLPEE------------LR 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 292 YLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVltpirsleylllhsnqlreqgihPLAfqglkrLHTVHLYNNAL 371
Cdd:PRK15370 287 YLSVYDNSIRTLPAHLPSGITHLNVQSNSLTALPETL-----------------------PPG------LKTLEAGENAL 337
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 372 ERVPSGLPRRVRTLMILHNQITgIGREDFATTyfLEELNLSYNRITSpqvhrdafrklrllrsldlsgnrlhtLPPGLPR 451
Cdd:PRK15370 338 TSLPASLPPELQVLDVSKNQIT-VLPETLPPT--ITTLDVSRNALTN--------------------------LPENLPA 388
|
330
....*....|....*
gi 1719757105 452 NVHVLKVKRNELAAL 466
Cdd:PRK15370 389 ALQIMQASRNNLVRL 403
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
300-540 |
4.15e-14 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 75.50 E-value: 4.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 300 LSRVPAGLPRSLVLLHLEKNAIRSVDANvltpirsleyllLHSNqlreqgihplafqglkrLHTVHLYNNALERVPSGLP 379
Cdd:PRK15370 190 LTTIPACIPEQITTLILDNNELKSLPEN------------LQGN-----------------IKTLYANSNQLTSIPATLP 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 380 RRVRTLMILHNQITGIgREDFATTyfLEELNLSYNRITS-PQVHRDAFRKLRLLRsldlsgNRLHTLPPGLPRNVHVLKV 458
Cdd:PRK15370 241 DTIQEMELSINRITEL-PERLPSA--LQSLDLFHNKISClPENLPEELRYLSVYD------NSIRTLPAHLPSGITHLNV 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 459 KRNELAALARGALVGmaqLRELYLTSNRLRS--RALGPRawvdlahLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISA 536
Cdd:PRK15370 312 QSNSLTALPETLPPG---LKTLEAGENALTSlpASLPPE-------LQVLDVSKNQITVLPETLPPTITTLDVSRNALTN 381
|
....
gi 1719757105 537 VPAN 540
Cdd:PRK15370 382 LPEN 385
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
247-558 |
1.44e-13 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 73.04 E-value: 1.44e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 247 NNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDA 326
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 327 NVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPR--RVRTLMILHNQITGIGrEDFATTY 404
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLP-EPLGNLT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 405 FLEELNLSYNRITSpqvhrdafrklrllrsldlsgnrlhtLPPGLPR--NVHVLKVKRNELAALArGALVGMAQLRELYL 482
Cdd:COG4886 160 NLKSLDLSNNQLTD--------------------------LPEELGNltNLKELDLSNNQITDLP-EPLGNLTNLEELDL 212
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1719757105 483 TSNRLRSRalgPRAWVDLAHLQLLDIAGNQLTEIPE--GLPeSLEYLYLQNNKISAVPANAfdSTPNLKGIFLRFNKL 558
Cdd:COG4886 213 SGNQLTDL---PEPLANLTNLETLDLSNNQLTDLPElgNLT-NLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQL 284
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
238-300 |
9.55e-13 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 63.31 E-value: 9.55e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1719757105 238 PALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTdeGLDNETFWKLSSLEYLDLSSNNL 300
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
222-424 |
2.43e-11 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 63.65 E-value: 2.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 222 LILSSNFLRHVPK-HLPPALYKLHLKNNKLEKIPpgAFSELSSLRELYLQNNYLTD-EGLDNetfwkLSSLEYLDLSSNN 299
Cdd:cd21340 7 LYLNDKNITKIDNlSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKiENLEN-----LVNLKKLYLGGNR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 300 LSRVpAGL--PRSLVLLHLEKNAIRS-----VDANVLTPI-RSLEYLLLHSNQLREqgIHPLAfqGLKRLhtvhlynnal 371
Cdd:cd21340 80 ISVV-EGLenLTNLEELHIENQRLPPgekltFDPRSLAALsNSLRVLNISGNNIDS--LEPLA--PLRNL---------- 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 1719757105 372 ervpsglprrvRTLMILHNQITGIGR--EDFATTYFLEELNLSYNRITSPQVHRD 424
Cdd:cd21340 145 -----------EQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVCKKPKYRD 188
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
55-385 |
2.47e-11 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 66.72 E-value: 2.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 55 SPEEPGPGPAAVSCP-RDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKI--YPEElsrlhrLETLNLQNNR 131
Cdd:PRK15387 180 APAEESRGRAAVVQKmRACLNNGNAVLNVGESGLTTLPDCLPAHITTLVIPDNNLTSLpaLPPE------LRTLEVSGNQ 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 132 LTSRG-LPEKAFEhltnlnyLYLANNKLTLAPRfLPNALISVDFAANYLTKIYGLtfgqKPNLRSVYLHNNKLAD-AGLP 209
Cdd:PRK15387 254 LTSLPvLPPGLLE-------LSIFSNPLTHLPA-LPSGLCKLWIFGNQLTSLPVL----PPGLQELSVSDNQLASlPALP 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 210 DNM-----FNGS--------SNVEVLILSSNFLRHVPKhLPPALYKLHLKNNKLEKIPpgafSELSSLRELYLQNNYLTD 276
Cdd:PRK15387 322 SELcklwaYNNQltslptlpSGLQELSVSDNQLASLPT-LPSELYKLWAYNNRLTSLP----ALPSGLKELIVSGNRLTS 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 277 EGLdnetfwKLSSLEYLDLSSNNLSRVPAgLPRSLVLLHLEKNAIRSVDANvLTPIRSLEYLLLHSNQLREQgihplAFQ 356
Cdd:PRK15387 397 LPV------LPSELKELMVSGNRLTSLPM-LPSGLLSLSVYRNQLTRLPES-LIHLSSETTVNLEGNPLSER-----TLQ 463
|
330 340 350
....*....|....*....|....*....|..
gi 1719757105 357 GLKRLHTVHLYNNAL---ERVPSGLPRRVRTL 385
Cdd:PRK15387 464 ALREITSAPGYSGPIirfDMAGASAPRETRAL 495
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
119-343 |
6.35e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 59.41 E-value: 6.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 119 LHRLETLNLQNNRLTSRGlpekAFEHLTNLNYLYLANNKltlaprflpnalisvdfaanyLTKIYGLTFGqkPNLRSVYL 198
Cdd:cd21340 1 LKRITHLYLNDKNITKID----NLSLCKNLKVLYLYDNK---------------------ITKIENLEFL--TNLTHLYL 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 199 HNNKladaglpdnmfngssnvevlILSSNFLRHVPKhlppaLYKLHLKNNKLEKIppGAFSELSSLRELYLQNNYL-TDE 277
Cdd:cd21340 54 QNNQ--------------------IEKIENLENLVN-----LKKLYLGGNRISVV--EGLENLTNLEELHIENQRLpPGE 106
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1719757105 278 GL--DNETFWKLS-SLEYLDLSSNNLSRV-PAGLPRSLVLLHLEKNAIRSVD--ANVLTPIRSLEYLLLHSN 343
Cdd:cd21340 107 KLtfDPRSLAALSnSLRVLNISGNNIDSLePLAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGN 178
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
100-303 |
9.24e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 59.03 E-value: 9.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 100 HLSLQNNQLEKIypEELSRLHRLETLNLQNNRLTS-RGLpekafEHLTNLNYLYLANNKltlaprflpnalisvdfaany 178
Cdd:cd21340 6 HLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKiENL-----EFLTNLTHLYLQNNQ--------------------- 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 179 LTKIYGLtfGQKPNLRSVYLHNNKLadaglpdnmfngsSNVEVLilssnflrhvpkHLPPALYKLHLKNNKLekiPPG-- 256
Cdd:cd21340 58 IEKIENL--ENLVNLKKLYLGGNRI-------------SVVEGL------------ENLTNLEELHIENQRL---PPGek 107
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 1719757105 257 -AFSELS------SLRELYLQNNYLTDegLDNetFWKLSSLEYLDLSSNNLSRV 303
Cdd:cd21340 108 lTFDPRSlaalsnSLRVLNISGNNIDS--LEP--LAPLRNLEQLDASNNQISDL 157
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
214-594 |
4.77e-09 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 59.48 E-value: 4.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 214 NGSSNVEVLILSSnflRHVPKHLPPALYKL------HLKNNKLE-KIPPGAFSELSSLRELYLQNNYLTdeGLDNETFwk 286
Cdd:PLN00113 66 NNSSRVVSIDLSG---KNISGKISSAIFRLpyiqtiNLSNNQLSgPIPDDIFTTSSSLRYLNLSNNNFT--GSIPRGS-- 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 287 LSSLEYLDLSSNNLS-RVPA--GLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLreQGIHPLAFQGLKRLHT 363
Cdd:PLN00113 139 IPNLETLDLSNNMLSgEIPNdiGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQL--VGQIPRELGQMKSLKW 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 364 VHL-YNNALERVPsglprrvrtlmilhNQITGIGRedfattyfLEELNLSYNRITSPqvhrdafrklrllrsldlsgnrl 442
Cdd:PLN00113 217 IYLgYNNLSGEIP--------------YEIGGLTS--------LNHLDLVYNNLTGP----------------------- 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 443 htLPPglprnvhvlkvkrnelaalargALVGMAQLRELYLTSNRLRSRAlgPRAWVDLAHLQLLDIAGNQLT-EIPEGLP 521
Cdd:PLN00113 252 --IPS----------------------SLGNLKNLQYLFLYQNKLSGPI--PPSIFSLQKLISLDLSDNSLSgEIPELVI 305
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1719757105 522 E--SLEYLYLQNNKISAVPANAFDSTPnlkgiflrfnklavgsvvdsafrrlkHLQVLDIEGNLEFGDISKDRGR 594
Cdd:PLN00113 306 QlqNLEILHLFSNNFTGKIPVALTSLP--------------------------RLQVLQLWSNKFSGEIPKNLGK 354
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
234-417 |
5.34e-09 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 58.14 E-value: 5.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 234 KHLPPALYKLHLKNNKLEKIPPG------AFSELSSLRELYLQNNYLTDEGLDN-ETFWKLSSLEYLDLSSNNLS----- 301
Cdd:cd00116 47 LRPQPSLKELCLSLNETGRIPRGlqsllqGLTKGCGLQELDLSDNALGPDGCGVlESLLRSSSLQELKLNNNGLGdrglr 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 302 ---RVPAGLPRSLVLLHLEKNAIRSVD----ANVLTPIRSLEYLLLHSNQLREQGIHPLAfQGLK---RLHTVHLYNNAL 371
Cdd:cd00116 127 llaKGLKDLPPALEKLVLGRNRLEGAScealAKALRANRDLKELNLANNGIGDAGIRALA-EGLKancNLEVLDLNNNGL 205
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 1719757105 372 ERVPSGL-------PRRVRTLMILHNQITGIGREDFATTYF-----LEELNLSYNRIT 417
Cdd:cd00116 206 TDEGASAlaetlasLKSLEVLNLGDNNLTDAGAAALASALLspnisLLTLSLSCNDIT 263
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
101-304 |
8.83e-09 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 55.95 E-value: 8.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 101 LSLQNNQLEKIypEELSRLHRLETLNLQNNRLTS-RGLpekafEHLTNLNYLYLANNKltlaprflpnalISVdfaanyl 179
Cdd:cd21340 29 LYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKiENL-----ENLVNLKKLYLGGNR------------ISV------- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 180 tkIYGLTfgQKPNLRSVYLHNNKLAdaglPDNMFngSSNVEVLILSSNFLRHvpkhlppalykLHLKNNKLEKIPPgaFS 259
Cdd:cd21340 83 --VEGLE--NLTNLEELHIENQRLP----PGEKL--TFDPRSLAALSNSLRV-----------LNISGNNIDSLEP--LA 139
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 1719757105 260 ELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVP 304
Cdd:cd21340 140 PLRNLEQLDASNNQISDLEELLDLLSSWPSLRELDLTGNPVCKKP 184
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
101-374 |
2.25e-08 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 56.21 E-value: 2.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 101 LSLQNNQLEKIYPEELSRLHR-LETLNLQNNRLTSRGLP--EKAFEHLTNLNYLYLANNKLTLAPRFLpnalisvDFAAN 177
Cdd:cd00116 3 LSLKGELLKTERATELLPKLLcLQVLRLEGNTLGEEAAKalASALRPQPSLKELCLSLNETGRIPRGL-------QSLLQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 178 YLTKIYGLT-------------------FGQKPNLRSVYLHNNKLADAGLPdnmfngssnvevlilssnFLRHVPKHLPP 238
Cdd:cd00116 76 GLTKGCGLQeldlsdnalgpdgcgvlesLLRSSSLQELKLNNNGLGDRGLR------------------LLAKGLKDLPP 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 239 ALYKLHLKNNKLEKIP----PGAFSELSSLRELYLQNNYLTDEGLDN--ETFWKLSSLEYLDLSSNnlsrvpaglprslV 312
Cdd:cd00116 138 ALEKLVLGRNRLEGAScealAKALRANRDLKELNLANNGIGDAGIRAlaEGLKANCNLEVLDLNNN-------------G 204
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1719757105 313 LLHLEKNAIrsvdANVLTPIRSLEYLLLHSNQLREQGIHPLAFQ---GLKRLHTVHLYNNALERV 374
Cdd:cd00116 205 LTDEGASAL----AETLASLKSLEVLNLGDNNLTDAGAAALASAllsPNISLLTLSLSCNDITDD 265
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
290-556 |
3.08e-08 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 56.71 E-value: 3.08e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 290 LEYLDLSSNNLSRVPAgLPRSLVLLHLEKNAIRSVDAnvlTPiRSLEYLLLHSNQLREQGIHPLAFQGLKrlhtvhLYNN 369
Cdd:PRK15387 244 LRTLEVSGNQLTSLPV-LPPGLLELSIFSNPLTHLPA---LP-SGLCKLWIFGNQLTSLPVLPPGLQELS------VSDN 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 370 ALERVPSgLPRRVRTLMILHNQITGIGredfATTYFLEELNLSYNRITS-PQVHRDAFRklrllrsLDLSGNRLHTLPpG 448
Cdd:PRK15387 313 QLASLPA-LPSELCKLWAYNNQLTSLP----TLPSGLQELSVSDNQLASlPTLPSELYK-------LWAYNNRLTSLP-A 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 449 LPRNVHVLKVKRNELAALArgalVGMAQLRELYLTSNRLRSRALGPRAWVDLAhlqlldIAGNQLTEIPEGLPE--SLEY 526
Cdd:PRK15387 380 LPSGLKELIVSGNRLTSLP----VLPSELKELMVSGNRLTSLPMLPSGLLSLS------VYRNQLTRLPESLIHlsSETT 449
|
250 260 270
....*....|....*....|....*....|...
gi 1719757105 527 LYLQNNKISAVPANAF---DSTPNLKGIFLRFN 556
Cdd:PRK15387 450 VNLEGNPLSERTLQALreiTSAPGYSGPIIRFD 482
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
414-540 |
3.58e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 56.63 E-value: 3.58e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 414 NRITSPQVHRDAFRKLRLLRSLDLSGnrLHTLPPGLPRNVHVLKVKRNELAALARGAlvgMAQLRELYLTSNRLRS---- 489
Cdd:PRK15370 164 NREEAVQRMRDCLKNNKTELRLKILG--LTTIPACIPEQITTLILDNNELKSLPENL---QGNIKTLYANSNQLTSipat 238
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1719757105 490 -------RALGPRAWVDL-----AHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPAN 540
Cdd:PRK15370 239 lpdtiqeMELSINRITELperlpSALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAH 301
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
359-582 |
4.21e-08 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 56.24 E-value: 4.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 359 KRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIgREDFATTyfLEELNLSYNRITSpqvhrdafrklrllrsldls 438
Cdd:PRK15370 199 EQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSI-PATLPDT--IQEMELSINRITE-------------------- 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 439 gnrlhtLPPGLPRNVHVLKVKRNELAALargalvgmaqlrelyltsnrlrsralgPRAWVDlaHLQLLDIAGNQLTEIPE 518
Cdd:PRK15370 256 ------LPERLPSALQSLDLFHNKISCL---------------------------PENLPE--ELRYLSVYDNSIRTLPA 300
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1719757105 519 GLPESLEYLYLQNNKISAVPANAfdsTPNLKgiFLRFNKLAVGSVVDSAfrrLKHLQVLDIEGN 582
Cdd:PRK15370 301 HLPSGITHLNVQSNSLTALPETL---PPGLK--TLEAGENALTSLPASL---PPELQVLDVSKN 356
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
208-492 |
7.21e-08 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 55.55 E-value: 7.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 208 LPDNMfngSSNVEVLILSSNFLRHVPKhLPPALYKLHLKNNKLEKIP---PGafselssLRELYLQNNYLTD-EGLDnet 283
Cdd:PRK15387 216 LPDCL---PAHITTLVIPDNNLTSLPA-LPPELRTLEVSGNQLTSLPvlpPG-------LLELSIFSNPLTHlPALP--- 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 284 fwklSSLEYLDLSSNNLSRVPAgLPRSLVLLHLEKNAIRSVDAnvlTPiRSLEYLLLHSNQLREQGIHPLAFQGLKrlht 363
Cdd:PRK15387 282 ----SGLCKLWIFGNQLTSLPV-LPPGLQELSVSDNQLASLPA---LP-SELCKLWAYNNQLTSLPTLPSGLQELS---- 348
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 364 vhLYNNALERVPSgLPRRVRTLMILHNQITGIGredfATTYFLEELNLSYNRITSPQVHRDAFRKLRLLrsldlsGNRLH 443
Cdd:PRK15387 349 --VSDNQLASLPT-LPSELYKLWAYNNRLTSLP----ALPSGLKELIVSGNRLTSLPVLPSELKELMVS------GNRLT 415
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 1719757105 444 TLPPgLPRNVHVLKVKRNELAALARgALVGMAQLRELYLTSNRLRSRAL 492
Cdd:PRK15387 416 SLPM-LPSGLLSLSVYRNQLTRLPE-SLIHLSSETTVNLEGNPLSERTL 462
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
101-158 |
2.19e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.90 E-value: 2.19e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 1719757105 101 LSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSrgLPEKAFEHLTNLNYLYLANNKL 158
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
191-274 |
2.47e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.90 E-value: 2.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 191 PNLRSVYLHNNKLADagLPDNMFNGSSNVEVLILSsnflrhvpkhlppalyklhlkNNKLEKIPPGAFSELSSLRELYLQ 270
Cdd:pfam13855 1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLS---------------------NNLLTTLSPGAFSGLPSLRYLDLS 57
|
....
gi 1719757105 271 NNYL 274
Cdd:pfam13855 58 GNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
243-440 |
4.18e-07 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 50.94 E-value: 4.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 243 LHLKNNKLEKIppGAFSELSSLRELYLQNNYLTD-EGLDNetfwkLSSLEYLDLSSNNLSRVP--AGLPRsLVLLHLEKN 319
Cdd:cd21340 7 LYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKiENLEF-----LTNLTHLYLQNNQIEKIEnlENLVN-LKKLYLGGN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 320 AIRSVDAnvLTPIRSLEYLLLHSNQLREQgiHPLAFQglkrlhtvhlynnalERVPSGLPRRVRTLMILHNQITGIgrED 399
Cdd:cd21340 79 RISVVEG--LENLTNLEELHIENQRLPPG--EKLTFD---------------PRSLAALSNSLRVLNISGNNIDSL--EP 137
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 1719757105 400 FATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGN 440
Cdd:cd21340 138 LAPLRNLEQLDASNNQISDLEELLDLLSSWPSLRELDLTGN 178
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
75-418 |
4.97e-07 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 52.48 E-value: 4.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 75 SQEGVVDCGGIDLREFPGDLPEHTNHLS---LQNNQLEKIYPEELSRL--HRLETLNLQNNRLTSRGLPekafehltnln 149
Cdd:COG5238 64 RFEGQGDPGLNPVALEKAAEAFPTQLLVvdwEGAEEVSPVALAETATAvaTPPPDLRRIMAKTLEDSLI----------- 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 150 yLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLT-------FGQKPNLRSVYLHNNKLADAGLPD--NMFNGSSNVE 220
Cdd:COG5238 133 -LYLALPRRINLIQVLKDPLGGNAVHLLGLAARLGLLaaismakALQNNSVETVYLGCNQIGDEGIEElaEALTQNTTVT 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 221 VLILSSNflrHVPKHLPPALYKlHLKNNKlekippgafselsSLRELYLQNNYLTDEGLDN--ETFWKLSSLEYLDLSSN 298
Cdd:COG5238 212 TLWLKRN---PIGDEGAEILAE-ALKGNK-------------SLTTLDLSNNQIGDEGVIAlaEALKNNTTVETLYLSGN 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 299 NLSrvpaglprslvllhlEKNAIRSvdANVLTPIRSLEYLLLHSNQLREQGIHPLA--FQGLKRLHTVHL-YNNALERVP 375
Cdd:COG5238 275 QIG---------------AEGAIAL--AKALQGNTTLTSLDLSVNRIGDEGAIALAegLQGNKTLHTLNLaYNGIGAQGA 337
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 1719757105 376 SGLPRRVRTLMILH------NQITGIGREDFATtyFLE------ELNLSYNRITS 418
Cdd:COG5238 338 IALAKALQENTTLHsldlsdNQIGDEGAIALAK--YLEgnttlrELNLGKNNIGK 390
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
451-513 |
5.35e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 46.75 E-value: 5.35e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1719757105 451 RNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSraLGPRAWVDLAHLQLLDIAGNQL 513
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTT--LSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
262-345 |
9.93e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 9.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 262 SSLRELYLQNNYLTDegLDNETFWKLSSLEYLDLSSNNLSrvpaglprslvllhleknairSVDANVLTPIRSLEYLLLH 341
Cdd:pfam13855 1 PNLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLT---------------------TLSPGAFSGLPSLRYLDLS 57
|
....
gi 1719757105 342 SNQL 345
Cdd:pfam13855 58 GNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
363-571 |
2.56e-06 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 50.55 E-value: 2.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 363 TVHLYNNALERVPSgLPRRVRTLMILHNQITGIGredfattyFLEELNLSYNRITSPQVHRDAFrkLRLLRSLDLSGNRL 442
Cdd:PRK15387 226 TLVIPDNNLTSLPA-LPPELRTLEVSGNQLTSLP--------VLPPGLLELSIFSNPLTHLPAL--PSGLCKLWIFGNQL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 443 HTLPPgLPRNVHVLKVKRNELAALArgALVgmAQLRELYLTSNRLRSRALGPRAwvdlahLQLLDIAGNQLTEIPEgLPE 522
Cdd:PRK15387 295 TSLPV-LPPGLQELSVSDNQLASLP--ALP--SELCKLWAYNNQLTSLPTLPSG------LQELSVSDNQLASLPT-LPS 362
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 1719757105 523 SLEYLYLQNNKISAVPAnafdSTPNLKGIFLRFNKLAVGSVVDSAFRRL 571
Cdd:PRK15387 363 ELYKLWAYNNRLTSLPA----LPSGLKELIVSGNRLTSLPVLPSELKEL 407
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
523-583 |
2.98e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.82 E-value: 2.98e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1719757105 523 SLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLavGSVVDSAFRRLKHLQVLDIEGNL 583
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNR 60
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
476-534 |
3.96e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.44 E-value: 3.96e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1719757105 476 QLRELYLTSNRLRSraLGPRAWVDLAHLQLLDIAGNQLTEIPE----GLPeSLEYLYLQNNKI 534
Cdd:pfam13855 2 NLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLTTLSPgafsGLP-SLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
121-203 |
1.10e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 43.28 E-value: 1.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 121 RLETLNLQNNRLTSrgLPEKAFEHLTNLNYLYLANNKLTlapRFLPNALisvdfaanyltkiYGLtfgqkPNLRSVYLHN 200
Cdd:pfam13855 2 NLRSLDLSNNRLTS--LDDGAFKGLSNLKVLDLSNNLLT---TLSPGAF-------------SGL-----PSLRYLDLSG 58
|
...
gi 1719757105 201 NKL 203
Cdd:pfam13855 59 NRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
502-558 |
5.39e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.36 E-value: 5.39e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 502 HLQLLDIAGNQLTEIPEGL---PESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKL 558
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAfkgLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
75-298 |
1.26e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 44.27 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 75 SQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLE----KIYPEELSRLHRLETLNLQNNRLTSRGLPE--KAFEHLTNL 148
Cdd:cd00116 116 NNNGLGDRGLRLLAKGLKDLPPALEKLVLGRNRLEgascEALAKALRANRDLKELNLANNGIGDAGIRAlaEGLKANCNL 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 149 NYLYLANNKLTLAPrflpnaliSVDFAAnyltkiyglTFGQKPNLRSVYLHNNKLADAGLPDnmfngssnvevlILSSNf 228
Cdd:cd00116 196 EVLDLNNNGLTDEG--------ASALAE---------TLASLKSLEVLNLGDNNLTDAGAAA------------LASAL- 245
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1719757105 229 lrhvpKHLPPALYKLHLKNNKLEKIPPGAFSEL----SSLRELYLQNNYLTDEG---LDNETFWKLSSLEYLDLSSN 298
Cdd:cd00116 246 -----LSPNISLLTLSLSCNDITDDGAKDLAEVlaekESLLELDLRGNKFGEEGaqlLAESLLEPGNELESLWVKDD 317
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
314-556 |
3.99e-04 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 42.08 E-value: 3.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 314 LHLEKNAIRSVDAnvLTPIRSLEYLLLHSNQLREqgIHPLAFqgLKRLHTVHLYNNALERVP--SGLPRrvrtlmilhnq 391
Cdd:cd21340 7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITK--IENLEF--LTNLTHLYLQNNQIEKIEnlENLVN----------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 392 itgigredfattyfLEELNLSYNRITspqvhrdafrklrllrsldlsgnrlhtlppglprnvhVLKvkrnelaalargAL 471
Cdd:cd21340 70 --------------LKKLYLGGNRIS-------------------------------------VVE------------GL 86
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 472 VGMAQLRELYLTSNRLRSR---ALGPRAWVDLAH-LQLLDIAGNQLTEIpEGLP--ESLEYLYLQNNKISAVP--ANAFD 543
Cdd:cd21340 87 ENLTNLEELHIENQRLPPGeklTFDPRSLAALSNsLRVLNISGNNIDSL-EPLAplRNLEQLDASNNQISDLEelLDLLS 165
|
250
....*....|...
gi 1719757105 544 STPNLKGIFLRFN 556
Cdd:cd21340 166 SWPSLRELDLTGN 178
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
266-587 |
4.05e-04 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 42.73 E-value: 4.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 266 ELYLQNNYLTDEGLDnETFWKLSSLEYLDLSSNNLSRVPAglprslvllhleknairSVDANVLTPIRSLEYLLLHSNQL 345
Cdd:cd00116 2 QLSLKGELLKTERAT-ELLPKLLCLQVLRLEGNTLGEEAA-----------------KALASALRPQPSLKELCLSLNET 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 346 REQ----GIHPLAFQGLKRLHTVHLYNNALervpsglprrvrtlmilhnQITGIGR-EDFATTYFLEELNLSYNRItspq 420
Cdd:cd00116 64 GRIprglQSLLQGLTKGCGLQELDLSDNAL-------------------GPDGCGVlESLLRSSSLQELKLNNNGL---- 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 421 vhrdafrklrllrsLDLSGNRLHTLPPGLPRNVHVLKVKRNEL-----AALArGALVGMAQLRELYLTSNRLRS---RAL 492
Cdd:cd00116 121 --------------GDRGLRLLAKGLKDLPPALEKLVLGRNRLegascEALA-KALRANRDLKELNLANNGIGDagiRAL 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 493 GpRAWVDLAHLQLLDIAGNQLTE-----IPEGLPE--SLEYLYLQNNKISAVPANAFDS-----TPNLKGIFLRFNKLAV 560
Cdd:cd00116 186 A-EGLKANCNLEVLDLNNNGLTDegasaLAETLASlkSLEVLNLGDNNLTDAGAAALASallspNISLLTLSLSCNDITD 264
|
330 340
....*....|....*....|....*....
gi 1719757105 561 GSVVDSA--FRRLKHLQVLDIEGNlEFGD 587
Cdd:cd00116 265 DGAKDLAevLAEKESLLELDLRGN-KFGE 292
|
|
| LRRNT |
smart00013 |
Leucine rich repeat N-terminal domain; |
68-98 |
4.35e-04 |
|
Leucine rich repeat N-terminal domain;
Pssm-ID: 214470 [Multi-domain] Cd Length: 33 Bit Score: 38.07 E-value: 4.35e-04
10 20 30
....*....|....*....|....*....|.
gi 1719757105 68 CPRDCACSqEGVVDCGGIDLREFPGDLPEHT 98
Cdd:smart00013 2 CPAPCNCS-GTAVDCSGRGLTEVPLDLPPDT 31
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
442-539 |
5.87e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 42.84 E-value: 5.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 442 LHTLPPGLPRNVHVLKVKRNELAALArgALVgmAQLRELYLTSNRLRSRALGPRAWVDLA-------HLQLLD------- 507
Cdd:PRK15387 213 LTTLPDCLPAHITTLVIPDNNLTSLP--ALP--PELRTLEVSGNQLTSLPVLPPGLLELSifsnpltHLPALPsglcklw 288
|
90 100 110
....*....|....*....|....*....|..
gi 1719757105 508 IAGNQLTEIPEgLPESLEYLYLQNNKISAVPA 539
Cdd:PRK15387 289 IFGNQLTSLPV-LPPGLQELSVSDNQLASLPA 319
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
406-487 |
1.62e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.12 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 406 LEELNLSYNRITSpqVHRDAFRklrllrsldlsgnrlhtlppGLPrNVHVLKVKRNELAALARGALVGMAQLRELYLTSN 485
Cdd:pfam13855 3 LRSLDLSNNRLTS--LDDGAFK--------------------GLS-NLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGN 59
|
..
gi 1719757105 486 RL 487
Cdd:pfam13855 60 RL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
96-132 |
3.53e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 35.96 E-value: 3.53e-03
10 20 30
....*....|....*....|....*....|....*..
gi 1719757105 96 EHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRL 132
Cdd:pfam13855 25 SNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
240-307 |
3.79e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 40.18 E-value: 3.79e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1719757105 240 LYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTdeGLDNETFWKLSSLEYLDLSSNNLS-RVPAGL 307
Cdd:PLN03150 444 LQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFN--GSIPESLGQLTSLRILNLNGNSLSgRVPAAL 510
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
263-300 |
5.06e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 35.30 E-value: 5.06e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1719757105 263 SLRELYLQNNYLTDEGLdnetFWKLSSLEYLDLSSNNL 300
Cdd:pfam12799 2 NLEVLDLSNNQITDIPP----LAKLPNLETLDLSGNNK 35
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
121-158 |
6.47e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 34.91 E-value: 6.47e-03
10 20 30
....*....|....*....|....*....|....*...
gi 1719757105 121 RLETLNLQNNRLTSRGLPEKafehLTNLNYLYLANNKL 158
Cdd:pfam12799 2 NLEVLDLSNNQITDIPPLAK----LPNLETLDLSGNNK 35
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
309-371 |
7.84e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 35.19 E-value: 7.84e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1719757105 309 RSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLreQGIHPLAFQGLKRLHTVHLYNNAL 371
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLL--TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
305-558 |
9.55e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 38.62 E-value: 9.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 305 AGLPRSLVLLHLEKNAIRSVDANVLTPIRsleyLLLHSNQL-REQGIHPLAFQGLKRLHTVHLYNN-----ALERVPSGL 378
Cdd:COG5238 129 DSLILYLALPRRINLIQVLKDPLGGNAVH----LLGLAARLgLLAAISMAKALQNNSVETVYLGCNqigdeGIEELAEAL 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 379 --PRRVRTLMILHNQITGIGREDFA----TTYFLEELNLSYNRITSPQVHrdAFRKLRLLrsldlsGNRLHTLppGLPRN 452
Cdd:COG5238 205 tqNTTVTTLWLKRNPIGDEGAEILAealkGNKSLTTLDLSNNQIGDEGVI--ALAEALKN------NTTVETL--YLSGN 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1719757105 453 vhvlKVKRNELAALARgALVGMAQLRELYLTSNRlrsraLGPRAWVDLA-HLQ------LLDIAGNQLTE-----IPEGL 520
Cdd:COG5238 275 ----QIGAEGAIALAK-ALQGNTTLTSLDLSVNR-----IGDEGAIALAeGLQgnktlhTLNLAYNGIGAqgaiaLAKAL 344
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 1719757105 521 PE--SLEYLYLQNNKIS----AVPANAFDSTPNLKGIFLRFNKL 558
Cdd:COG5238 345 QEntTLHSLDLSDNQIGdegaIALAKYLEGNTTLRELNLGKNNI 388
|
|
| |
