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Conserved domains on  [gi|307574674|ref|NP_001182606|]
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vesicle-associated membrane protein-associated protein B/C isoform 2 [Homo sapiens]

Protein Classification

motile sperm domain-containing protein( domain architecture ID 10457611)

motile sperm domain-containing protein may form filaments, similar to major motile sperm protein (MSP) and vesicle-associated membrane protein-associated proteins

CATH:  2.60.40.10
SCOP:  4007566

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Motile_Sperm pfam00635
MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These ...
 8-90 4.52e-26

MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These proteins oligomerise to form filaments. This family contains many other proteins.


:

Pssm-ID: 459882  Cd Length: 109  Bit Score: 92.81  E-value: 4.52e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307574674    8 LSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGASINVSGRRWTADEEDSAEQQPH 87
Cdd:pfam00635   2 LTIDPPDLIFFAAPGNKQGTSTLTLKNTSDKRVAFKVKTTNPKKYRVRPNYGIIKPGESVTITITRQPFDEEPGDAKKDK 81


                  ...
gi 307574674   88 FSI 90
Cdd:pfam00635  82 FVI 84
 
Name Accession Description Interval E-value
Motile_Sperm pfam00635
MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These ...
 8-90 4.52e-26

MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These proteins oligomerise to form filaments. This family contains many other proteins.


Pssm-ID: 459882  Cd Length: 109  Bit Score: 92.81  E-value: 4.52e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307574674    8 LSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGASINVSGRRWTADEEDSAEQQPH 87
Cdd:pfam00635   2 LTIDPPDLIFFAAPGNKQGTSTLTLKNTSDKRVAFKVKTTNPKKYRVRPNYGIIKPGESVTITITRQPFDEEPGDAKKDK 81


                  ...
gi 307574674   88 FSI 90
Cdd:pfam00635  82 FVI 84
SCS2 COG5066
VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and ...
 8-69 7.88e-16

VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and secretion];


Pssm-ID: 227398 [Multi-domain]  Cd Length: 242  Bit Score: 69.61  E-value: 7.88e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 307574674   8 LSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGASINV 69
Cdd:COG5066    1 MAVEISPQTTFYVPLTNKSKEMFSVQNNSPEPVGFKVKTTAPKDYCVRPNMGLIEPMSTVEV 62
 
Name Accession Description Interval E-value
Motile_Sperm pfam00635
MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These ...
 8-90 4.52e-26

MSP (Major sperm protein) domain; Major sperm proteins are involved in sperm motility. These proteins oligomerise to form filaments. This family contains many other proteins.


Pssm-ID: 459882  Cd Length: 109  Bit Score: 92.81  E-value: 4.52e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 307574674    8 LSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGASINVSGRRWTADEEDSAEQQPH 87
Cdd:pfam00635   2 LTIDPPDLIFFAAPGNKQGTSTLTLKNTSDKRVAFKVKTTNPKKYRVRPNYGIIKPGESVTITITRQPFDEEPGDAKKDK 81


                  ...
gi 307574674   88 FSI 90
Cdd:pfam00635  82 FVI 84
SCS2 COG5066
VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and ...
 8-69 7.88e-16

VAMP-associated protein involved in inositol metabolism [Intracellular trafficking and secretion];


Pssm-ID: 227398 [Multi-domain]  Cd Length: 242  Bit Score: 69.61  E-value: 7.88e-16
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 307574674   8 LSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGASINV 69
Cdd:COG5066    1 MAVEISPQTTFYVPLTNKSKEMFSVQNNSPEPVGFKVKTTAPKDYCVRPNMGLIEPMSTVEV 62
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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