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Conserved domains on  [gi|301171536|ref|NP_001180350|]
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teashirt homolog 2 isoform 2 [Homo sapiens]

Protein Classification

homeobox domain-containing protein( domain architecture ID 10052840)

homeobox domain-containing protein may be involved in the transcriptional regulation of key eukaryotic developmental processes

Gene Ontology:  GO:0003677|GO:0006357|GO:0043565
PubMed:  1357790|26464018|21557080

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 839-907 1.76e-03

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


:

Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 37.61  E-value: 1.76e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 301171536  839 KGRQSNWNPQHLLILQAQFASSlfqtsegKYLlsdlGPQERMQISKFTGLSMTTISHWLANVKYQLRKT 907
Cdd:cd00086     1 RRKRTRFTPEQLEELEKEFEKN-------PYP----SREEREELAKELGLTERQVKIWFQNRRAKLKRS 58
 
Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 839-907 1.76e-03

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 37.61  E-value: 1.76e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 301171536  839 KGRQSNWNPQHLLILQAQFASSlfqtsegKYLlsdlGPQERMQISKFTGLSMTTISHWLANVKYQLRKT 907
Cdd:cd00086     1 RRKRTRFTPEQLEELEKEFEKN-------PYP----SREEREELAKELGLTERQVKIWFQNRRAKLKRS 58
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 837-905 4.04e-03

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 36.46  E-value: 4.04e-03
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 301171536    837 KRKGRQSnWNPQHLLILQAQFAsslfqtsEGKYLlsdlGPQERMQISKFTGLSMTTISHWLANVKYQLR 905
Cdd:smart00389    1 KRRKRTS-FTPEQLEELEKEFQ-------KNPYP----SREEREELAKKLGLSERQVKVWFQNRRAKWK 57
 
Name Accession Description Interval E-value
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 839-907 1.76e-03

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 37.61  E-value: 1.76e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 301171536  839 KGRQSNWNPQHLLILQAQFASSlfqtsegKYLlsdlGPQERMQISKFTGLSMTTISHWLANVKYQLRKT 907
Cdd:cd00086     1 RRKRTRFTPEQLEELEKEFEKN-------PYP----SREEREELAKELGLTERQVKIWFQNRRAKLKRS 58
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 837-905 4.04e-03

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 36.46  E-value: 4.04e-03
                            10        20        30        40        50        60
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 301171536    837 KRKGRQSnWNPQHLLILQAQFAsslfqtsEGKYLlsdlGPQERMQISKFTGLSMTTISHWLANVKYQLR 905
Cdd:smart00389    1 KRRKRTS-FTPEQLEELEKEFQ-------KNPYP----SREEREELAKKLGLSERQVKVWFQNRRAKWK 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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