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Conserved domains on  [gi|258679511|ref|NP_001158307|]
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LINE-1 type transposase domain-containing protein 1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tnp_22_dsRBD super family cl38762
L1 transposable element dsRBD-like domain; This entry represents the double stranded ...
 799-860 2.49e-13

L1 transposable element dsRBD-like domain; This entry represents the double stranded RNA-binding-like domain.


The actual alignment was detected with superfamily member pfam17490:

Pssm-ID: 407521  Cd Length: 65  Bit Score: 65.51  E-value: 2.49e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 258679511  799 DTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEFRDYVLHMPTLRELL 860
Cdd:pfam17490   2 ETLQARREWGPIFNILKEKNFQPRISYPAKLSFISEGEIKYFIDKQ*LRDFVTTRPALKELL 63
Tnp_22_dsRBD super family cl38762
L1 transposable element dsRBD-like domain; This entry represents the double stranded ...
 251-315 1.80e-12

L1 transposable element dsRBD-like domain; This entry represents the double stranded RNA-binding-like domain.


The actual alignment was detected with superfamily member pfam17490:

Pssm-ID: 407521  Cd Length: 65  Bit Score: 63.20  E-value: 1.80e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 258679511  251 SATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKD 315
Cdd:pfam17490   1 AETLQARREWGPIFNILKEKNFQPRISYPAKLSFISEGEIKYFIDKQ*LRDFVTTRPALKELLKE 65
Transposase_22 super family cl25509
L1 transposable element RBD-like domain; This entry represents the RBD-like domain.
 701-795 1.61e-07

L1 transposable element RBD-like domain; This entry represents the RBD-like domain.


The actual alignment was detected with superfamily member pfam02994:

Pssm-ID: 460776 [Multi-domain]  Cd Length: 98  Bit Score: 50.12  E-value: 1.61e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679511  701 NIRLIGIPEKESyENRAEDIIKEI--IDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASR 778
Cdd:pfam02994   3 NLRLICDPEEDR-ENAAEDEINEIdiEGEFFEKLAKQAEQQIQEIQDTPKRPNLRLAGPPEIDVEFGKKEEKEKQDIAAE 81

                          90
                  ....*....|....*..
gi 258679511  779 ERREITYQGTRIRLTAD 795
Cdd:pfam02994  82 EFGNLALKAKPIILEID 98
 
Name Accession Description Interval E-value
Tnp_22_dsRBD pfam17490
L1 transposable element dsRBD-like domain; This entry represents the double stranded ...
 799-860 2.49e-13

L1 transposable element dsRBD-like domain; This entry represents the double stranded RNA-binding-like domain.


Pssm-ID: 407521  Cd Length: 65  Bit Score: 65.51  E-value: 2.49e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 258679511  799 DTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEFRDYVLHMPTLRELL 860
Cdd:pfam17490   2 ETLQARREWGPIFNILKEKNFQPRISYPAKLSFISEGEIKYFIDKQ*LRDFVTTRPALKELL 63
Tnp_22_dsRBD pfam17490
L1 transposable element dsRBD-like domain; This entry represents the double stranded ...
 251-315 1.80e-12

L1 transposable element dsRBD-like domain; This entry represents the double stranded RNA-binding-like domain.


Pssm-ID: 407521  Cd Length: 65  Bit Score: 63.20  E-value: 1.80e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 258679511  251 SATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKD 315
Cdd:pfam17490   1 AETLQARREWGPIFNILKEKNFQPRISYPAKLSFISEGEIKYFIDKQ*LRDFVTTRPALKELLKE 65
Transposase_22 pfam02994
L1 transposable element RBD-like domain; This entry represents the RBD-like domain.
 701-795 1.61e-07

L1 transposable element RBD-like domain; This entry represents the RBD-like domain.


Pssm-ID: 460776 [Multi-domain]  Cd Length: 98  Bit Score: 50.12  E-value: 1.61e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679511  701 NIRLIGIPEKESyENRAEDIIKEI--IDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASR 778
Cdd:pfam02994   3 NLRLICDPEEDR-ENAAEDEINEIdiEGEFFEKLAKQAEQQIQEIQDTPKRPNLRLAGPPEIDVEFGKKEEKEKQDIAAE 81

                          90
                  ....*....|....*..
gi 258679511  779 ERREITYQGTRIRLTAD 795
Cdd:pfam02994  82 EFGNLALKAKPIILEID 98
 
Name Accession Description Interval E-value
Tnp_22_dsRBD pfam17490
L1 transposable element dsRBD-like domain; This entry represents the double stranded ...
 799-860 2.49e-13

L1 transposable element dsRBD-like domain; This entry represents the double stranded RNA-binding-like domain.


Pssm-ID: 407521  Cd Length: 65  Bit Score: 65.51  E-value: 2.49e-13
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 258679511  799 DTLDARSKWSNVFKVLLEKGFNPRILYPAKMAFDFRGKTKVFLSIEEFRDYVLHMPTLRELL 860
Cdd:pfam17490   2 ETLQARREWGPIFNILKEKNFQPRISYPAKLSFISEGEIKYFIDKQ*LRDFVTTRPALKELL 63
Tnp_22_dsRBD pfam17490
L1 transposable element dsRBD-like domain; This entry represents the double stranded ...
 251-315 1.80e-12

L1 transposable element dsRBD-like domain; This entry represents the double stranded RNA-binding-like domain.


Pssm-ID: 407521  Cd Length: 65  Bit Score: 63.20  E-value: 1.80e-12
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 258679511  251 SATLDISKQWSNVFNILRENDFEPKFLCEVKLAFKCDGEIKTFSDLQSLRKFASQKSSVKELLKD 315
Cdd:pfam17490   1 AETLQARREWGPIFNILKEKNFQPRISYPAKLSFISEGEIKYFIDKQ*LRDFVTTRPALKELLKE 65
Transposase_22 pfam02994
L1 transposable element RBD-like domain; This entry represents the RBD-like domain.
 701-795 1.61e-07

L1 transposable element RBD-like domain; This entry represents the RBD-like domain.


Pssm-ID: 460776 [Multi-domain]  Cd Length: 98  Bit Score: 50.12  E-value: 1.61e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 258679511  701 NIRLIGIPEKESyENRAEDIIKEI--IDENFAELKKGSSLEIVSACRVPSKIDEKRLTPRHILVKFWNSSDKEKIIRASR 778
Cdd:pfam02994   3 NLRLICDPEEDR-ENAAEDEINEIdiEGEFFEKLAKQAEQQIQEIQDTPKRPNLRLAGPPEIDVEFGKKEEKEKQDIAAE 81

                          90
                  ....*....|....*..
gi 258679511  779 ERREITYQGTRIRLTAD 795
Cdd:pfam02994  82 EFGNLALKAKPIILEID 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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