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Conserved domains on  [gi|229892345|ref|NP_001153517|]
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zinc finger protein GLI1 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 434-953 6.83e-09

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 60.34  E-value: 6.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  434 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 510
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  511 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 590
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  591 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 669
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  670 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 749
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  750 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 829
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  830 NHKSGSYPTPSPCHENFVVGANRAShraaappRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 909
Cdd:PHA03247 2985 SREAPASSTPPLTGHSLSRVSSWAS-------SLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 229892345  910 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 953
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC super family cl24666
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 109-137 2.28e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


The actual alignment was detected with superfamily member pfam16159:

Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.28e-06
                          10        20
                  ....*....|....*....|....*....
gi 229892345  109 CRWDGCSQEFDSQEQLVHHINSEHIHGER 137
Cdd:pfam16159   7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 169-259 4.55e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 4.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 169 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 248
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                         90
                 ....*....|.
gi 229892345 249 SSLRKHVKTVH 259
Cdd:COG5189  412 NGLKYHRKHSH 422
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 434-953 6.83e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 60.34  E-value: 6.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  434 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 510
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  511 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 590
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  591 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 669
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  670 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 749
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  750 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 829
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  830 NHKSGSYPTPSPCHENFVVGANRAShraaappRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 909
Cdd:PHA03247 2985 SREAPASSTPPLTGHSLSRVSSWAS-------SLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 229892345  910 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 953
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 109-137 2.28e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.28e-06
                          10        20
                  ....*....|....*....|....*....
gi 229892345  109 CRWDGCSQEFDSQEQLVHHINSEHIHGER 137
Cdd:pfam16159   7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 169-259 4.55e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 4.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 169 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 248
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                         90
                 ....*....|.
gi 229892345 249 SSLRKHVKTVH 259
Cdd:COG5189  412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
189-216 2.52e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.52e-05
                          10        20
                  ....*....|....*....|....*...
gi 229892345  189 NLKTHLRSHTGEKPYMCEHegCSKAFSN 216
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
68-305 2.13e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 2.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  68 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 140
Cdd:COG5236  117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 141 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 211
Cdd:COG5236  193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 212 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 270
Cdd:COG5236  258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 229892345 271 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 305
Cdd:COG5236  333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
 
Name Accession Description Interval E-value
PHA03247 PHA03247
large tegument protein UL36; Provisional
 434-953 6.83e-09

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 60.34  E-value: 6.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  434 ASPFPPGSPPENGASSLPGLMPAQH-YLLRARYASARGGGTSPTAASSLDRIGGLPMPP--WRSRAEYPGYNPNAGVTRR 510
Cdd:PHA03247 2622 HAPDPPPPSPSPAANEPDPHPPPTVpPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPqrPRRRAARPTVGSLTSLADP 2701

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  511 ASDPAQAADRPAPArvqrfksLGCVHTPPTVAGGGQNFdPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGL 590
Cdd:PHA03247 2702 PPPPPTPEPAPHAL-------VSATPLPPGPAAARQAS-PALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPA 2773

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  591 NPYMDFPPTDTLGYGGPEGAAAEPY-GARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALG 669
Cdd:PHA03247 2774 APAAGPPRRLTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  670 GTYSQCprlehyGQVQVKPEQGCPVGSDSTGLAPclnahPSEGPPHPQPLFSHYPQPSPPqylqSGPYTQPPPDyLPSEP 749
Cdd:PHA03247 2854 GSVAPG------GDVRRRPPSRSPAAKPAAPARP-----PVRRLARPAVSRSTESFALPP----DQPERPPQPQ-APPPP 2917

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  750 RPCLDFDSPTHSTGQLKAQlvcnyVQSQQELLWEGGgreDAPAQEPSYQSPKFLGGSQVsPSRAKAPvNTYGPgfgPNLP 829
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPP-----PRPQPPLAPTTD---PAGAGEPSGAVPQPWLGALV-PGRVAVP-RFRVP---QPAP 2984

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  830 NHKSGSYPTPSPCHENFVVGANRAShraaappRLLPPLPTCYGPLKVGGTnpscghpevgrlgggpaLYPPPEGQVCNPL 909
Cdd:PHA03247 2985 SREAPASSTPPLTGHSLSRVSSWAS-------SLALHEETDPPPVSLKQT-----------------LWPPDDTEDSDAD 3040

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 229892345  910 DSLDLDNTQLDFVAILDEPQGLSPPPSHdqrgssghtPPPSGPP 953
Cdd:PHA03247 3041 SLFDSDSERSDLEALDPLPPEPHDPFAH---------EPDPATP 3075
FOXP-CC pfam16159
FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found ...
 109-137 2.28e-06

FOXP coiled-coil domain; This domain, approximately 60-70 residues in length, is mainly found in Forkhead box proteins in various Mammalia species. It is a coiled-coil domain, which modulates the dimeric associations of FOXP transcription factors. Several key disease mutations, for instance those found in the IPEX syndrome are located in this domain


Pssm-ID: 465036  Cd Length: 68  Bit Score: 45.75  E-value: 2.28e-06
                          10        20
                  ....*....|....*....|....*....
gi 229892345  109 CRWDGCSQEFDSQEQLVHHINSEHIHGER 137
Cdd:pfam16159   7 CRWPGCETVCEDFGSFLKHLNSEHALDDR 35
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 169-259 4.55e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 50.10  E-value: 4.55e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 169 GEKPHKCTFEGCRKSYSRLENLKTHLRshtgekpymceHEGCSKAFSNASDRAKHQNRTHSNeKPYVCklPGCTKRYTDP 248
Cdd:COG5189  346 DGKPYKCPVEGCNKKYKNQNGLKYHML-----------HGHQNQKLHENPSPEKMNIFSAKD-KPYRC--EVCDKRYKNL 411

                         90
                 ....*....|.
gi 229892345 249 SSLRKHVKTVH 259
Cdd:COG5189  412 NGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
189-216 2.52e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.97  E-value: 2.52e-05
                          10        20
                  ....*....|....*....|....*...
gi 229892345  189 NLKTHLRSHTGEKPYMCEHegCSKAFSN 216
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
159-186 3.04e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 41.59  E-value: 3.04e-05
                          10        20
                  ....*....|....*....|....*...
gi 229892345  159 MLVVHMRRHTGEKPHKCTFegCRKSYSR 186
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPE--CGKSFKS 26
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 597-749 3.16e-05

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 48.16  E-value: 3.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  597 PPTDTLGYGGPEGAAAEPYGARGPGSLPLGPGP---PTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKAlgGTYS 673
Cdd:PRK10263  339 PVTQTPPVASVDVPPAQPTVAWQPVPGPQTGEPviaPAPEGYPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPAA--EQPA 416

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 229892345  674 QCPRLEHYGQVQVKPEQGCPVGSDSTGLAPcLNAHPSEGPPHPQPLF---SHYPQPSPPQYLQSGPYTQPPPDYLPSEP 749
Cdd:PRK10263  417 QQPYYAPAPEQPAQQPYYAPAPEQPVAGNA-WQAEEQQSTFAPQSTYqteQTYQQPAAQEPLYQQPQPVEQQPVVEPEP 494
PHA03247 PHA03247
large tegument protein UL36; Provisional
 383-742 1.12e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 46.47  E-value: 1.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  383 PIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPglmpaqhyllr 462
Cdd:PHA03247 2751 PGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALP----------- 2819

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  463 aryASARGGGTSPTAASSLDRIGGLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPTVA 542
Cdd:PHA03247 2820 ---PAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTE 2896

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  543 GGGQNFD-PYLPTSVYSPQPPSITENAAMDARGLQEEPEvgtsmvgSGLNPYMDFPPTDTLGYGGPEGAAAEPY-GARGP 620
Cdd:PHA03247 2897 SFALPPDqPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP-------PPRPQPPLAPTTDPAGAGEPSGAVPQPWlGALVP 2969

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  621 GSLPL------GPGPPTNYGPNPCPQQASYPDPTQETWGE-FPSHSGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQgcP 693
Cdd:PHA03247 2970 GRVAVprfrvpQPAPSREAPASSTPPLTGHSLSRVSSWASsLALHEETDPPPVSLKQTLWPPDDTEDSDADSLFDSD--S 3047

                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|..
gi 229892345  694 VGSDSTGLAPclnahpseGPPHPQPLFSHYPQPSPPQY-LQSGPYTQ--PPP 742
Cdd:PHA03247 3048 ERSDLEALDP--------LPPEPHDPFAHEPDPATPEAgARESPSSQfgPPP 3091
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
171-251 1.27e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.84  E-value: 1.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 171 KPHKCtfEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNaSDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSS 250
Cdd:COG5048   32 RPDSC--PNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSR-PLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108


                 .
gi 229892345 251 L 251
Cdd:COG5048  109 S 109
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
163-219 1.96e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 45.07  E-value: 1.96e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 229892345 163 HMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASD 219
Cdd:COG5048   52 HIRSHTGEKPSQCSYSGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS 108
dnaA PRK14086
chromosomal replication initiator protein DnaA;
635-855 5.76e-04

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 43.66  E-value: 5.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 635 PNPCPQQASYPDPTQETWGEFPSHSglYPGPKALggtysqcPRLEHYGQVQVKPEqgcpvgsdSTGLAPCLNAHPSEGPp 714
Cdd:PRK14086  96 APPPPHARRTSEPELPRPGRRPYEG--YGGPRAD-------DRPPGLPRQDQLPT--------ARPAYPAYQQRPEPGA- 157

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 715 HPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEP-RPCLDFDSPTHSTGQLKaqlvcnyvQSQQELLWEGGGREDAPAQ 793
Cdd:PRK14086 158 WPRAADDYGWQQQRLGFPPRAPYASPASYAPEQERdREPYDAGRPEYDQRRRD--------YDHPRPDWDRPRRDRTDRP 229

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 229892345 794 EPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSgSYPTPSPCH---------ENFVVGA-NRASH 855
Cdd:PRK14086 230 EPPPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPA-PAPGPGEPTarlnpkytfDTFVIGAsNRFAH 300
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
147-254 8.19e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.15  E-value: 8.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 147 CSRELRPFKAQYMLVVHMR--RHTGE--KPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCEHEGCSKAFSNASDRAK 222
Cdd:COG5048  292 SKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNEP 371

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 229892345 223 HQ----NRTHSNEKPYVCKLPGCTKRYTDPSSLRKH 254
Cdd:COG5048  372 PQslqqYKDLKNDKKSETLSNSCIRNFKRDSNLSLH 407
PHA03247 PHA03247
large tegument protein UL36; Provisional
 434-911 1.19e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  434 ASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASsldrigglPMPPWRSRAEYPGYNPNAgvtrrASD 513
Cdd:PHA03247 2552 PPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSAR--------PRAPVDDRGDPRGPAPPS-----PLP 2618

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  514 PAQAA-DRPAPARVQRFKSLGCVHTPPTVAGGGQNFDPYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSgLNP 592
Cdd:PHA03247 2619 PDTHApDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGS-LTS 2697

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  593 YMDFPPtdtlgyggPEGAAAEPYGARGPGsLPLGPGPPTNYGPNPCPQQASYPDPTQETwGEFPSHSGLYPGPKALGGTY 672
Cdd:PHA03247 2698 LADPPP--------PPPTPEPAPHALVSA-TPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPARPPTTAGPP 2767

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  673 SQCPrlehyGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPDYLPSEPRPC 752
Cdd:PHA03247 2768 APAP-----PAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPP 2842

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  753 LDFDSPTHSTgqlkaqlvCNYVQSQQELLWEGGGREDAPA-QEPSYQSPKFLGGSQVSPSRAKAPVNTYGPgfgPNLPNH 831
Cdd:PHA03247 2843 PGPPPPSLPL--------GGSVAPGGDVRRRPPSRSPAAKpAAPARPPVRRLARPAVSRSTESFALPPDQP---ERPPQP 2911

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  832 KSGSYPTPSPCHENfvvgANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLggGPALYPPPEGQVCNPLDS 911
Cdd:PHA03247 2912 QAPPPPQPQPQPPP----PPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAL--VPGRVAVPRFRVPQPAPS 2985
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
392-524 1.93e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 1.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 392 PSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFPPGSPPENGASSLPGLMPAQHYLLRARYASARGG 471
Cdd:PRK12323 365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 229892345 472 GTSPTAASSLdriggLPMPPWRSRAEYPGYNPNAGVTRRASDPAQAADRPAPA 524
Cdd:PRK12323 445 GGAPAPAPAP-----AAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPA 492
COG5236 COG5236
Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];
68-305 2.13e-03

Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only];


Pssm-ID: 227561 [Multi-domain]  Cd Length: 493  Bit Score: 41.93  E-value: 2.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345  68 EGDMSSPNSTGIQDPLLGMLDGREDLereeKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEH-------IHGERKEF 140
Cdd:COG5236  117 PADITDRRQWKGREEKVGIFYEGEDV----RDEMEDLLSFKCPKSKCHRRCGSLKELKKHYKAQHgfvlcseCIGNKKDF 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 141 VChwggcsrELRPFKAQymlvvHMRRH-------TGEKPH-KCTFegCRKSYSRLENLKTHLRSHTgEKPYMCEHEGCS- 211
Cdd:COG5236  193 WN-------EIRLFRSS-----TLRDHknggleeEGFKGHpLCIF--CKIYFYDDDELRRHCRLRH-EACHICDMVGPIr 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 212 -KAFSNASDRAKHQNRTHsnekpYVCKLPGCTKR----YTDPSSLRKHVKTVHGPDAHVT----------------KRHR 270
Cdd:COG5236  258 yQYFKSYEDLEAHFRNAH-----YCCTFQTCRVGkcyvFPYHTELLEHLTRFHKVNARLSeiprpgrcsipvmdpfKRKK 332

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 229892345 271 GDGPLPRAPSI--STVEPKREREGGPIREESRLTVPE 305
Cdd:COG5236  333 APARVSVIDPSggNARAPMAHRGGSRQDTASPSTEAE 369
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
100-236 3.99e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.83  E-value: 3.99e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 100 EPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGE-RKEFVCHWGGCSRelrPFKAQYMLVVHMRRHTGEKPHKCTFE 178
Cdd:COG5048  281 SSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNHSGEsLKPFSCPYSLCGK---LFSRNDALKRHILLHTSISPAKEKLL 357

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 229892345 179 GCRKSYSRLEN-----------------------------------LKTHLRSHTGEKPYMCEHEGCSKAFSNASDrAKH 223
Cdd:COG5048  358 NSSSKFSPLLNneppqslqqykdlkndkksetlsnscirnfkrdsnLSLHIITHLSFRPYNCKNPPCSKSFNRHYN-LIP 436

                        170
                 ....*....|...
gi 229892345 224 QNRTHSNEKPYVC 236
Cdd:COG5048  437 HKKIHTNHAPLLC 449
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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