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Conserved domains on  [gi|55749577|ref|NP_001142|]
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ADP/ATP translocase 1 [Homo sapiens]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 7-298 6.84e-157

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 439.59  E-value: 6.84e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577    7 SFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEK--QYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPT 84
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKvpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577   85 QALNFAFKDKYKQLFlGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAaQREFHGLGDCIIKI 164
Cdd:PTZ00169  86 QAFNFAFKDYFKNMF-PKYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASDIGKGG-DREFTGLFDCLMKI 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577  165 FKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGML-PDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSG 243
Cdd:PTZ00169 164 SKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLfGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMMSG 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 55749577  244 RK-GADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV 298
Cdd:PTZ00169 244 RKaKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAGGALVLVFYDELQKLL 299
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 7-298 6.84e-157

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 439.59  E-value: 6.84e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577    7 SFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEK--QYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPT 84
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKvpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577   85 QALNFAFKDKYKQLFlGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAaQREFHGLGDCIIKI 164
Cdd:PTZ00169  86 QAFNFAFKDYFKNMF-PKYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASDIGKGG-DREFTGLFDCLMKI 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577  165 FKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGML-PDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSG 243
Cdd:PTZ00169 164 SKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLfGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMMSG 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 55749577  244 RK-GADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV 298
Cdd:PTZ00169 244 RKaKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAGGALVLVFYDELQKLL 299
Mito_carr pfam00153
Mitochondrial carrier protein;
7-101 5.29e-29

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 106.59  E-value: 5.29e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577     7 SFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQisaeKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQA 86
Cdd:pfam00153   4 SFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGK----SKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAA 79

                          90
                  ....*....|....*
gi 55749577    87 LNFAFKDKYKQLFLG 101
Cdd:pfam00153  80 IYFGTYETLKRLLLK 94
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 7-298 6.84e-157

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 439.59  E-value: 6.84e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577    7 SFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEK--QYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPT 84
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGKvpRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577   85 QALNFAFKDKYKQLFlGGVDRHKQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAaQREFHGLGDCIIKI 164
Cdd:PTZ00169  86 QAFNFAFKDYFKNMF-PKYNQKTDFWKFFGVNILSGGLAGASSLLIVYPLDFARTRLASDIGKGG-DREFTGLFDCLMKI 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577  165 FKSDGLRGLYQGFNVSVQGIIIYRAAYFGVYDTAKGML-PDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSG 243
Cdd:PTZ00169 164 SKQTGFLSLYQGFGVSVQGIIVYRGAYFGLYDSAKALLfGNDKNTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMMSG 243

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 55749577  244 RK-GADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYV 298
Cdd:PTZ00169 244 RKaKSEIQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAGGALVLVFYDELQKLL 299
Mito_carr pfam00153
Mitochondrial carrier protein;
7-101 5.29e-29

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 106.59  E-value: 5.29e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577     7 SFLKDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQisaeKQYKGIIDCVVRIPKEQGFLSFWRGNLANVIRYFPTQA 86
Cdd:pfam00153   4 SFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGK----SKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAA 79

                          90
                  ....*....|....*
gi 55749577    87 LNFAFKDKYKQLFLG 101
Cdd:pfam00153  80 IYFGTYETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
109-206 3.75e-25

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 96.19  E-value: 3.75e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577   109 FWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKGAAQRefHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYR 188
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKG--RGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78

                          90
                  ....*....|....*...
gi 55749577   189 AAYFGVYDTAKGMLPDPK 206
Cdd:pfam00153  79 AIYFGTYETLKRLLLKKL 96
Mito_carr pfam00153
Mitochondrial carrier protein;
211-297 2.88e-19

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 80.78  E-value: 2.88e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577   211 FVSWMIAqsvTAVAGLVSYPFDTVRRRMMMQSGRKGAdiMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LV 289
Cdd:pfam00153   9 LLAGGIA---GAIAVTVTYPLDVVKTRLQVQGGSGKS--KGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAIyFG 83


                  ....*...
gi 55749577   290 LYDEIKKY 297
Cdd:pfam00153  84 TYETLKRL 91
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
 116-238 6.87e-04

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 40.29  E-value: 6.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 55749577  116 NLASGGAAGATSLCFVYPLDFARTRLAADvgkgaaqrefhglgdciiKIFKSDGLRGLYQGFNVSVQGIIIYRAAYFGVY 195
Cdd:PTZ00168   6 NLVTGALSGVIVDAVLYPIDSIKTNIQAK------------------KSFSFSDIKKLYSGILPTLVGTVPASAFFYCFY 67

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 55749577  196 DTAKGMLPDPK-NVHIFVSWMIAQSVTAV-AGLVSYPFDTVRRRM 238
Cdd:PTZ00168  68 ELSKKLLTEYReNISKTNLYLISTSIAEItACIVRLPFEIVKQNM 112
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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