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Conserved domains on  [gi|525313748|ref|NP_001139110|]
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G-protein-signaling modulator 1 isoform a [Homo sapiens]

Protein Classification

TPR and TPR_12 domain-containing protein( domain architecture ID 11421204)

protein containing domains TPR, TPR_12, and GoLoco

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
210-464 2.55e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 2.55e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 210 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLrdqaveA 289
Cdd:COG0457    9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE------ALYNLGLAYLRLGRYEEALADYEQALELDPDD------A 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 290 QACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADrvgegrACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDrhgel 369
Cdd:COG0457   77 EALNNLGLALQALGRYEEALEDYDKALELDPDDAE------ALYNLGLALLELGRYDEAIEAYERALELDPDDAD----- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 370 tARMNVAQLQLVLGRLTSPAAS-EKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLEREQNGDSHHSGDWRGPSRDSLPL 448
Cdd:COG0457  146 -ALYNLGIALEKLGRYEEALELlEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLL 224

                        250
                 ....*....|....*.
gi 525313748 449 PVRSRKYQEGPDAERR 464
Cdd:COG0457  225 LALALLLALRLAALAL 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
69-325 1.21e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.97  E-value: 1.21e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  69 YSQLGNAYFYLKEHGRALEYHKHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQgdkvgeARA 148
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 149 LYNIGNVYHAKGKqlswnaanatqdpghlppdvretLCKASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEA 228
Cdd:COG0457   79 LNNLGLALQALGR-----------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEA 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 229 TTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERA 308
Cdd:COG0457  130 IEAYERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLAL 203

                        250
                 ....*....|....*..
gi 525313748 309 AEYHLRHLLIAQELADR 325
Cdd:COG0457  204 EQALRKKLAILTLAALA 220
GoLoco pfam02188
GoLoco motif;
496-517 4.13e-07

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 46.26  E-value: 4.13e-07
                          10        20
                  ....*....|....*....|..
gi 525313748  496 ECFFDLLTKFQSSRMDDQRCPL 517
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
597-617 7.26e-06

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.79  E-value: 7.26e-06
                          10        20
                  ....*....|....*....|.
gi 525313748  597 DDFFNMLIKYQSSRIDDQRCP 617
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco pfam02188
GoLoco motif;
549-569 1.24e-05

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.24e-05
                          10        20
                  ....*....|....*....|.
gi 525313748  549 EEFFDLIASSQSRRLDDQRAS 569
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco pfam02188
GoLoco motif;
631-652 1.28e-05

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.28e-05
                          10        20
                  ....*....|....*....|..
gi 525313748  631 EDFFSLIQRVQAKRMDEQRVDL 652
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
210-464 2.55e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 2.55e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 210 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLrdqaveA 289
Cdd:COG0457    9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE------ALYNLGLAYLRLGRYEEALADYEQALELDPDD------A 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 290 QACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADrvgegrACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDrhgel 369
Cdd:COG0457   77 EALNNLGLALQALGRYEEALEDYDKALELDPDDAE------ALYNLGLALLELGRYDEAIEAYERALELDPDDAD----- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 370 tARMNVAQLQLVLGRLTSPAAS-EKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLEREQNGDSHHSGDWRGPSRDSLPL 448
Cdd:COG0457  146 -ALYNLGIALEKLGRYEEALELlEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLL 224

                        250
                 ....*....|....*.
gi 525313748 449 PVRSRKYQEGPDAERR 464
Cdd:COG0457  225 LALALLLALRLAALAL 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
69-325 1.21e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.97  E-value: 1.21e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  69 YSQLGNAYFYLKEHGRALEYHKHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQgdkvgeARA 148
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 149 LYNIGNVYHAKGKqlswnaanatqdpghlppdvretLCKASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEA 228
Cdd:COG0457   79 LNNLGLALQALGR-----------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEA 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 229 TTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERA 308
Cdd:COG0457  130 IEAYERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLAL 203

                        250
                 ....*....|....*..
gi 525313748 309 AEYHLRHLLIAQELADR 325
Cdd:COG0457  204 EQALRKKLAILTLAALA 220
TPR_12 pfam13424
Tetratricopeptide repeat;
210-281 9.91e-10

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 55.47  E-value: 9.91e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 525313748  210 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEF--GDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQ 281
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco pfam02188
GoLoco motif;
496-517 4.13e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 46.26  E-value: 4.13e-07
                          10        20
                  ....*....|....*....|..
gi 525313748  496 ECFFDLLTKFQSSRMDDQRCPL 517
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
597-617 7.26e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.79  E-value: 7.26e-06
                          10        20
                  ....*....|....*....|.
gi 525313748  597 DDFFNMLIKYQSSRIDDQRCP 617
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 596-618 1.14e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 42.10  E-value: 1.14e-05
                           10        20
                   ....*....|....*....|...
gi 525313748   596 GDDFFNMLIKYQSSRIDDQRCPP 618
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
549-569 1.24e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.24e-05
                          10        20
                  ....*....|....*....|.
gi 525313748  549 EEFFDLIASSQSRRLDDQRAS 569
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco pfam02188
GoLoco motif;
631-652 1.28e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.28e-05
                          10        20
                  ....*....|....*....|..
gi 525313748  631 EDFFSLIQRVQAKRMDEQRVDL 652
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 548-570 2.78e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 41.33  E-value: 2.78e-05
                           10        20
                   ....*....|....*....|...
gi 525313748   548 TEEFFDLIASSQSRRLDDQRASV 570
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 495-517 3.55e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 40.95  E-value: 3.55e-05
                           10        20
                   ....*....|....*....|...
gi 525313748   495 EECFFDLLTKFQSSRMDDQRCPL 517
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 210-385 4.10e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 46.84  E-value: 4.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 210 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKE-FGDKAAE-RRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDqAV 287
Cdd:NF040586 479 MTAGGLGADLRALGRFREALELDEETLERHRRvFGEDHPRtLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLG-PD 557

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 288 EAQACYSLGN---TYTLLQDYERAAEY---HLRHLLIAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQE 361
Cdd:NF040586 558 HPRTLLSANNlarDLRELGRYAEALDLleeALERYREVLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRR 637

                        170       180
                 ....*....|....*....|....*.
gi 525313748 362 I-GDRHGE-LTARMNVAQLQLVLGRL 385
Cdd:NF040586 638 RfGPDHPDtLAAALSLANDLRALGDA 663
TPR_12 pfam13424
Tetratricopeptide repeat;
106-162 8.52e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 8.52e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 525313748  106 AKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQ--GDKVGEARALYNIGNVYHAKGKQ 162
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRY 61
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 630-652 8.99e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 39.79  E-value: 8.99e-05
                           10        20
                   ....*....|....*....|...
gi 525313748   630 DEDFFSLIQRVQAKRMDEQRVDL 652
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 40-434 3.82e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 43.75  E-value: 3.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  40 KAGDFKTGVAFFEAAVQV-----GTEDLKTLSAiYSQLGNAYFYLKEHGRALEyhkhdllLARTIGDRMGEAK------- 107
Cdd:NF040586 404 LRGDYESARDLAERALERwrerlGPDDRQTLRL-RFHLANALRSLGRYEEARE-------LDEDTLERQRRVLglgedhp 475

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 108 ----ASGNLGNTLKVLGRFDEAavccqrhLSIAQEqgdkvgearalynignvyhakgkqlSWNAANATqdpghLPPDVRE 183
Cdd:NF040586 476 htlmTAGGLGADLRALGRFREA-------LELDEE-------------------------TLERHRRV-----FGEDHPR 518

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 184 TLckasefyernlslvkelgdraaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFG--DKAAERRAYSNLGNAHVF 261
Cdd:NF040586 519 TL------------------------RAANNLAVSLRLLGDYREALELDREVLRRRRRVLgpDHPRTLLSANNLARDLRE 574

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 262 LGRFDVAAEYYKKTLQLSRQLR---DQAVEAQACYSLGNTYTLLQDYERAAEyHLRHLLiaQELADRVGEG----RAC-W 333
Cdd:NF040586 575 LGRYAEALDLLEEALERYREVLggpDHPDTLRAAKSLAVALRRAGRLEEALE-LAEDTY--ERYRRRFGPDhpdtLAAaL 651

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 334 SLGNAYVSMGRPAQALTFAKKHLQISQEI-GDRHG-ELTARMNVAQLQLVLGrltspaasekpdlagyEAQGARpkrtqR 411
Cdd:NF040586 652 SLANDLRALGDADEARELAREVLDRYRRVlGEDHPfTLACRNNLAVLLRALG----------------DPEEAR-----E 710

                        410       420
                 ....*....|....*....|...
gi 525313748 412 LSAETWDLLrlpleREQNGDSHH 434
Cdd:NF040586 711 LAEAALEGL-----RERLGPDHP 728
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 289-321 4.98e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 4.98e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 525313748   289 AQACYSLGNTYTLLQDYERAAEYHLRHLLIAQE 321
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 106-138 5.13e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 5.13e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 525313748   106 AKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQE 138
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
210-464 2.55e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 2.55e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 210 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLrdqaveA 289
Cdd:COG0457    9 EAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAE------ALYNLGLAYLRLGRYEEALADYEQALELDPDD------A 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 290 QACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADrvgegrACWSLGNAYVSMGRPAQALTFAKKHLQISQEIGDrhgel 369
Cdd:COG0457   77 EALNNLGLALQALGRYEEALEDYDKALELDPDDAE------ALYNLGLALLELGRYDEAIEAYERALELDPDDAD----- 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 370 tARMNVAQLQLVLGRLTSPAAS-EKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLEREQNGDSHHSGDWRGPSRDSLPL 448
Cdd:COG0457  146 -ALYNLGIALEKLGRYEEALELlEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLL 224

                        250
                 ....*....|....*.
gi 525313748 449 PVRSRKYQEGPDAERR 464
Cdd:COG0457  225 LALALLLALRLAALAL 240
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
105-372 2.75e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.90  E-value: 2.75e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 105 EAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEqgdkvgEARALYNIGNVYHAKGKqlswnaanatqdpghlppdvret 184
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPD------DAEALYNLGLAYLRLGR----------------------- 57

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 185 LCKASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGR 264
Cdd:COG0457   58 YEEALADYEQALEL------DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE------ALYNLGLALLELGR 125

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 265 FDVAAEYYKKTLQLSRQLrdqaveAQACYSLGNTYTLLQDYERAAEYHLRhlLIAQELADRVGEGRACWSLGNAYVSMGR 344
Cdd:COG0457  126 YDEAIEAYERALELDPDD------ADALYNLGIALEKLGRYEEALELLEK--LEAAALAALLAAALGEAALALAAAEVLL 197

                        250       260
                 ....*....|....*....|....*...
gi 525313748 345 PAQALTFAKKHLQISQEIGDRHGELTAR 372
Cdd:COG0457  198 ALLLALEQALRKKLAILTLAALAELLLL 225
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
69-325 1.21e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 76.97  E-value: 1.21e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  69 YSQLGNAYFYLKEHGRALEYHKHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQgdkvgeARA 148
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 149 LYNIGNVYHAKGKqlswnaanatqdpghlppdvretLCKASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEA 228
Cdd:COG0457   79 LNNLGLALQALGR-----------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEA 129

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 229 TTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERA 308
Cdd:COG0457  130 IEAYERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLAL 203

                        250
                 ....*....|....*..
gi 525313748 309 AEYHLRHLLIAQELADR 325
Cdd:COG0457  204 EQALRKKLAILTLAALA 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
145-427 4.12e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 75.43  E-value: 4.12e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 145 EARALYNIGNVYHAKGKQLswnaanatqdpghlppdvretlcKASEFYERNLSLVKELGDraaqgrAYGNLGNTHYLLGN 224
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYE-----------------------EAIEDYEKALELDPDDAE------ALYNLGLAYLRLGR 57

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 225 FTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLrdqaveAQACYSLGNTYTLLQD 304
Cdd:COG0457   58 YEEALADYEQALELDPDDAE------ALNNLGLALQALGRYEEALEDYDKALELDPDD------AEALYNLGLALLELGR 125

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 305 YERAAEYHLRHLLIAQELADrvgegrACWSLGNAYVSMGRPAQALTFAKKHLQisQEIGDRHGELTARMNVAQLQLVLGR 384
Cdd:COG0457  126 YDEAIEAYERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEA--AALAALLAAALGEAALALAAAEVLL 197

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 525313748 385 LTSPAASEKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLERE 427
Cdd:COG0457  198 ALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALAL 240
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 33-316 4.19e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 63.98  E-value: 4.19e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  33 LEGERLCKAGDFKTGVAFFEAAVQVGTEDLKTlsaiYSQLGNAYFYLKEHGRALEYHKHdlLLARTiGDRmgeAKASGNL 112
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEA----HLALGNLYRRRGEYDRAIRIHQK--LLERD-PDR---AEALLEL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 113 GNTLKVLGRFDEAAVCCQRHLSIAQEQgdkvgeARALYNIGNVYHAKGKqlsWNAANATQDP-GHLPPDVRETLCKASEF 191
Cdd:COG2956   83 AQDYLKAGLLDRAEELLEKLLELDPDD------AEALRLLAEIYEQEGD---WEKAIEVLERlLKLGPENAHAYCELAEL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 192 YER--NLSLVKELGDRAAQ-----GRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGdkaaerRAYSNLGNAHVFLGR 264
Cdd:COG2956  154 YLEqgDYDEAIEALEKALKldpdcARALLLLAELYLEQGDYEEAIAALERALEQDPDYL------PALPRLAELYEKLGD 227

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|..
gi 525313748 265 FDVAAEYYKKTLQLSRQLRDQaveaqacYSLGNTYTLLQDYERAAEYHLRHL 316
Cdd:COG2956  228 PEEALELLRKALELDPSDDLL-------LALADLLERKEGLEAALALLERQL 272
TPR_12 pfam13424
Tetratricopeptide repeat;
210-281 9.91e-10

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 55.47  E-value: 9.91e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 525313748  210 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEF--GDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQ 281
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 201-358 3.13e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 60.01  E-value: 3.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 201 ELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSR 280
Cdd:COG3914   70 AAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAE------ALFNLGNLLLALGRLEEALAALRRALALNP 143

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 525313748 281 QLrdqaveAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADrvgegrACWSLGNAYVSMGRPAQALTFAKKHLQI 358
Cdd:COG3914  144 DF------AEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAE------ALNNLGNALQDLGRLEEAIAAYRRALEL 209
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 206-361 8.32e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.43  E-value: 8.32e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 206 AAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQlrdq 285
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPE------AFALLGEILLQLGDLDEAIVLLHEALELDPD---- 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 525313748 286 avEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADrvgegrACWSLGNAYVSMGRPAQALTFAKKHLQISQE 361
Cdd:COG4783   71 --EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE------AYLRLARAYRALGRPDEAIAALEKALELDPD 138
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 192-385 1.15e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.08  E-value: 1.15e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 192 YERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEY 271
Cdd:COG3914   21 AAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALAL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 272 YKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADrvgegrACWSLGNAYVSMGRPAQALTF 351
Cdd:COG3914  101 YRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDFAE------AYLNLGEALRRLGRLEEAIAA 168

                        170       180       190
                 ....*....|....*....|....*....|....
gi 525313748 352 AKKHLQIsqeigdRHGELTARMNVAQLQLVLGRL 385
Cdd:COG3914  169 LRRALEL------DPDNAEALNNLGNALQDLGRL 196
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 111-362 1.72e-08

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.28  E-value: 1.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 111 NLGNTLKVLGRFDEAAVCCQRHLSIAQEQgdkvgeARALYNIGNVYHAKGKqlswnaanatqdpghlpPDvretlcKASE 190
Cdd:COG2956   47 ALGNLYRRRGEYDRAIRIHQKLLERDPDR------AEALLELAQDYLKAGL-----------------LD------RAEE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 191 FYERnlsLVKELGDRAaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEfgdkaaERRAYSNLGNAHVFLGRFDVAAE 270
Cdd:COG2956   98 LLEK---LLELDPDDA---EALRLLAEIYEQEGDWEKAIEVLERLLKLGPE------NAHAYCELAELYLEQGDYDEAIE 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 271 YYKKTLQLSRQlrdqAVEAQacYSLGNTYTLLQDYERAAEyHLRHLLIAQELADRVGEgracwSLGNAYVSMGRPAQALT 350
Cdd:COG2956  166 ALEKALKLDPD----CARAL--LLLAELYLEQGDYEEAIA-ALERALEQDPDYLPALP-----RLAELYEKLGDPEEALE 233

                        250
                 ....*....|..
gi 525313748 351 FAKKHLQISQEI 362
Cdd:COG2956  234 LLRKALELDPSD 245
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 211-324 3.80e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.54  E-value: 3.80e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 211 AYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLrdqaveAQ 290
Cdd:COG3914  114 ALFNLGNLLLALGRLEEALAALRRALALNPDFAE------AYLNLGEALRRLGRLEEAIAALRRALELDPDN------AE 181

                         90       100       110
                 ....*....|....*....|....*....|....
gi 525313748 291 ACYSLGNTYTLLQDYERAAEYHLRHLLIAQELAD 324
Cdd:COG3914  182 ALNNLGNALQDLGRLEEAIAAYRRALELDPDNAD 215
COG3899 COG3899
Predicted ATPase [General function prediction only];
201-427 1.28e-07

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 55.25  E-value: 1.28e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  201 ELGDRAAQGRAYGNLGntHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSR 280
Cdd:COG3899   784 RHGNPPASARAYANLG--LLLLGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGL 861

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  281 QLRDQAVEAQACYSLGNTyTLLQDYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQ 360
Cdd:COG3899   862 ETGDAALALLALAAAAAA-AAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAA 940

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 525313748  361 EIGDRHGELTARMNVAQLQLVLGRLTSPAASEKPDLAGYEAQGARPKRTQRLSAETWDLLRLPLERE 427
Cdd:COG3899   941 AAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAA 1007
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 1-281 1.93e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 54.23  E-value: 1.93e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748   1 MAGPAPPAADELPGPAARRLYSRMEASCLELALEGERLCKAGDFKTGVAFFEAAVQVGTEDLKTLSAIYSQLGNAYFYLK 80
Cdd:COG3914   13 AAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALG 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  81 EHGRALEYHKHDLLLARTigdrmgEAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQgdkvgeARALYNIGNVYHAKG 160
Cdd:COG3914   93 RYEEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDF------AEAYLNLGEALRRLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 161 KQLswnaanatqdpghlppdvretlcKASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAK 240
Cdd:COG3914  161 RLE-----------------------EAIAALRRALEL------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDP 211

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 525313748 241 EFgdkaaeRRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQ 281
Cdd:COG3914  212 DN------ADAHSNLLFALRQACDWEVYDRFEELLAALARG 246
GoLoco pfam02188
GoLoco motif;
496-517 4.13e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 46.26  E-value: 4.13e-07
                          10        20
                  ....*....|....*....|..
gi 525313748  496 ECFFDLLTKFQSSRMDDQRCPL 517
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_12 pfam13424
Tetratricopeptide repeat;
250-321 3.93e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.07  E-value: 3.93e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 525313748  250 RAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLR--DQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQE 321
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLLgpDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco pfam02188
GoLoco motif;
597-617 7.26e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.79  E-value: 7.26e-06
                          10        20
                  ....*....|....*....|.
gi 525313748  597 DDFFNMLIKYQSSRIDDQRCP 617
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
35-161 1.09e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 47.31  E-value: 1.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  35 GERLCKAGDFKTGVAFFEAAVQVGTEDlktlSAIYSQLGNAYFYLKEHGRALEYHKHDLLLartigdRMGEAKASGNLGN 114
Cdd:COG0457   49 GLAYLRLGRYEEALADYEQALELDPDD----AEALNNLGLALQALGRYEEALEDYDKALEL------DPDDAEALYNLGL 118

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 525313748 115 TLKVLGRFDEAAVCCQRHLSIaqeqgdKVGEARALYNIGNVYHAKGK 161
Cdd:COG0457  119 ALLELGRYDEAIEAYERALEL------DPDDADALYNLGIALEKLGR 159
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 596-618 1.14e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 42.10  E-value: 1.14e-05
                           10        20
                   ....*....|....*....|...
gi 525313748   596 GDDFFNMLIKYQSSRIDDQRCPP 618
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
549-569 1.24e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.24e-05
                          10        20
                  ....*....|....*....|.
gi 525313748  549 EEFFDLIASSQSRRLDDQRAS 569
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCS 21
GoLoco pfam02188
GoLoco motif;
631-652 1.28e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.28e-05
                          10        20
                  ....*....|....*....|..
gi 525313748  631 EDFFSLIQRVQAKRMDEQRVDL 652
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_12 pfam13424
Tetratricopeptide repeat;
293-361 2.04e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.14  E-value: 2.04e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 525313748  293 YSLGNTYTLLQDYERAAEYHLRHLLIAQEL--ADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQE 361
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 548-570 2.78e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 41.33  E-value: 2.78e-05
                           10        20
                   ....*....|....*....|...
gi 525313748   548 TEEFFDLIASSQSRRLDDQRASV 570
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 250-359 3.33e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.84  E-value: 3.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 250 RAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEyhlrhlLIAQELADRVGEG 329
Cdd:COG4235   18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPD------NADALLDLAEALLAAGDTEEAEE------LLERALALDPDNP 85

                         90       100       110
                 ....*....|....*....|....*....|
gi 525313748 330 RACWSLGNAYVSMGRPAQALTFAKKHLQIS 359
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 495-517 3.55e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 40.95  E-value: 3.55e-05
                           10        20
                   ....*....|....*....|...
gi 525313748   495 EECFFDLLTKFQSSRMDDQRCPL 517
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 210-385 4.10e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 46.84  E-value: 4.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 210 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKE-FGDKAAE-RRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDqAV 287
Cdd:NF040586 479 MTAGGLGADLRALGRFREALELDEETLERHRRvFGEDHPRtLRAANNLAVSLRLLGDYREALELDREVLRRRRRVLG-PD 557

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 288 EAQACYSLGN---TYTLLQDYERAAEY---HLRHLLIAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQE 361
Cdd:NF040586 558 HPRTLLSANNlarDLRELGRYAEALDLleeALERYREVLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAEDTYERYRR 637

                        170       180
                 ....*....|....*....|....*.
gi 525313748 362 I-GDRHGE-LTARMNVAQLQLVLGRL 385
Cdd:NF040586 638 RfGPDHPDtLAAALSLANDLRALGDA 663
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 246-385 4.46e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.64  E-value: 4.46e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 246 AAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYhlrhllIAQELADR 325
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPD------NPEAFALLGEILLQLGDLDEAIVL------LHEALELD 68

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 326 VGEGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEigdrHGEltARMNVAQLQLVLGRL 385
Cdd:COG4783   69 PDEPEARLNLGLALLKAGDYDEALALLEKALKLDPE----HPE--AYLRLARAYRALGRP 122
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 202-323 6.96e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 6.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 202 LGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQ 281
Cdd:COG5010   47 RDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE------LYYNLALLYSRSGDKDEAKEYYEKALALSPD 120

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 525313748 282 lrdqavEAQACYSLGNTYTLLQDYERAAEyHLRHLLIAQELA 323
Cdd:COG5010  121 ------NPNAYSNLAALLLSLGQDDEAKA-ALQRALGTSPLK 155
TPR_12 pfam13424
Tetratricopeptide repeat;
106-162 8.52e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 8.52e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 525313748  106 AKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQ--GDKVGEARALYNIGNVYHAKGKQ 162
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRY 61
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 630-652 8.99e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 39.79  E-value: 8.99e-05
                           10        20
                   ....*....|....*....|...
gi 525313748   630 DEDFFSLIQRVQAKRMDEQRVDL 652
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
187-284 1.76e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 187 KASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGNFTEATTFHKerlAIAKEFGDKaaerRAYSNLGNAHVFLGRFD 266
Cdd:COG3063   10 EAEEYYEKALEL------DPDNADALNNLGLLLLEQGRYDEAIALEK---ALKLDPNNA----EALLNLAELLLELGDYD 76

                         90
                 ....*....|....*...
gi 525313748 267 VAAEYYKKTLQLSRQLRD 284
Cdd:COG3063   77 EALAYLERALELDPSALR 94
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
210-357 1.99e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.37  E-value: 1.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 210 RAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQlRDQAV-- 287
Cdd:COG4785   74 QLYYERGVAYDSLGDYDLAIADFDQALELDPDLAE------AYNNRGLAYLLLGDYDAALEDFDRALELDPD-YAYAYln 146

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 525313748 288 EAQACYSLGNTYTLLQDYERAAEY-------HLRHLLIAQELADRVGEGRACWSLGNAYVSMGRPAQALTFAKKHLQ 357
Cdd:COG4785  147 RGIALYYLGRYELAIADLEKALELdpndperALWLYLAERKLDPEKALALLLEDWATAYLLQGDTEEARELFKLALA 223
TPR_12 pfam13424
Tetratricopeptide repeat;
187-241 2.04e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 40.06  E-value: 2.04e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 525313748  187 KASEFYERNLSLVKEL--GDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKE 241
Cdd:pfam13424  21 EALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
258-361 2.30e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.54  E-value: 2.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 258 AHVFLGRFDVAAEYYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYHlRHLLIAQELADrvgegrACWSLGN 337
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPD------NADALNNLGLLLLEQGRYDEAIALE-KALKLDPNNAE------ALLNLAE 67

                         90       100
                 ....*....|....*....|....
gi 525313748 338 AYVSMGRPAQALTFAKKHLQISQE 361
Cdd:COG3063   68 LLLELGDYDEALAYLERALELDPS 91
TPR_12 pfam13424
Tetratricopeptide repeat;
65-138 2.82e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.68  E-value: 2.82e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 525313748   65 LSAIYSQLGNAYFYLKEHGRALEYHKHDLLLARTI--GDRMGEAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQE 138
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR_7 pfam13176
Tetratricopeptide repeat;
291-325 2.91e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 38.68  E-value: 2.91e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 525313748  291 ACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADR 325
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDR 35
TPR_MalT pfam17874
MalT-like TPR region; This entry contains a series of TPR repeats.
 223-385 3.09e-04

MalT-like TPR region; This entry contains a series of TPR repeats.


Pssm-ID: 436107 [Multi-domain]  Cd Length: 336  Bit Score: 43.45  E-value: 3.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  223 GNFTEATTFHKERLAIAKEfgDKAAER-RAYSNLGNAHVFLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTL 301
Cdd:pfam17874  15 GDAERALELAEQALALLPE--DDLLARgLATFVLGEAYLCLGDLDAALQAMREAEALARRADSPHVTLWALLQQGEILRA 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  302 -------LQDYERAAEYHLRHLLIAQELAdrvgeGRACWSLGNAYVSMGRPAQALTFAKKHLQISQEiGDRHGELTARMN 374
Cdd:pfam17874  93 qgrlhqaLETYQQALQLARDHGLQHLPLH-----GFLLVGLADLLYEWNDLEEAEQHAQQGIQLGRQ-WEPDAAVDAYVL 166

                         170
                  ....*....|.
gi 525313748  375 VAQLQLVLGRL 385
Cdd:pfam17874 167 LARIALAQGEL 177
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 40-434 3.82e-04

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 43.75  E-value: 3.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  40 KAGDFKTGVAFFEAAVQV-----GTEDLKTLSAiYSQLGNAYFYLKEHGRALEyhkhdllLARTIGDRMGEAK------- 107
Cdd:NF040586 404 LRGDYESARDLAERALERwrerlGPDDRQTLRL-RFHLANALRSLGRYEEARE-------LDEDTLERQRRVLglgedhp 475

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 108 ----ASGNLGNTLKVLGRFDEAavccqrhLSIAQEqgdkvgearalynignvyhakgkqlSWNAANATqdpghLPPDVRE 183
Cdd:NF040586 476 htlmTAGGLGADLRALGRFREA-------LELDEE-------------------------TLERHRRV-----FGEDHPR 518

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 184 TLckasefyernlslvkelgdraaqgRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFG--DKAAERRAYSNLGNAHVF 261
Cdd:NF040586 519 TL------------------------RAANNLAVSLRLLGDYREALELDREVLRRRRRVLgpDHPRTLLSANNLARDLRE 574

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 262 LGRFDVAAEYYKKTLQLSRQLR---DQAVEAQACYSLGNTYTLLQDYERAAEyHLRHLLiaQELADRVGEG----RAC-W 333
Cdd:NF040586 575 LGRYAEALDLLEEALERYREVLggpDHPDTLRAAKSLAVALRRAGRLEEALE-LAEDTY--ERYRRRFGPDhpdtLAAaL 651

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 334 SLGNAYVSMGRPAQALTFAKKHLQISQEI-GDRHG-ELTARMNVAQLQLVLGrltspaasekpdlagyEAQGARpkrtqR 411
Cdd:NF040586 652 SLANDLRALGDADEARELAREVLDRYRRVlGEDHPfTLACRNNLAVLLRALG----------------DPEEAR-----E 710

                        410       420
                 ....*....|....*....|...
gi 525313748 412 LSAETWDLLrlpleREQNGDSHH 434
Cdd:NF040586 711 LAEAALEGL-----RERLGPDHP 728
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 258-354 4.51e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.36  E-value: 4.51e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 258 AHVFLGRFDVAAEYYKktlQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRhllIAQELADRVGEGRACWSLGN 337
Cdd:COG1729    2 ALLKAGDYDEAIAAFK---AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGL 75

                         90
                 ....*....|....*..
gi 525313748 338 AYVSMGRPAQALTFAKK 354
Cdd:COG1729   76 SYLELGDYDKARATLEE 92
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 198-317 7.23e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.99  E-value: 7.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 198 LVKELGDRAAQ----GRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDVAAEYYK 273
Cdd:COG4235    2 AIARLRQALAAnpndAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNAD------ALLDLAEALLAAGDTEEAEELLE 75

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 525313748 274 KTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYhLRHLL 317
Cdd:COG4235   76 RALALDPD------NPEALYLLGLAAFQQGDYAEAIAA-WQKLL 112
TPR_1 pfam00515
Tetratricopeptide repeat;
250-278 1.04e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.02  E-value: 1.04e-03
                          10        20
                  ....*....|....*....|....*....
gi 525313748  250 RAYSNLGNAHVFLGRFDVAAEYYKKTLQL 278
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALEL 30
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 255-361 1.23e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 41.25  E-value: 1.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 255 LGNAHVFLGRFDVAAEYYKKTLQLSRQlrdqavEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELAdrvgegRACWS 334
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEALELDPE------TVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRA------EALLE 81

                         90       100
                 ....*....|....*....|....*..
gi 525313748 335 LGNAYVSMGRPAQALTFAKKHLQISQE 361
Cdd:COG2956   82 LAQDYLKAGLLDRAEELLEKLLELDPD 108
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 30-161 1.77e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 39.02  E-value: 1.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  30 ELALEGERLCKAGDFKTGVAFFEAAVQVGTEDLktlsAIYSQLGNAYFYLKEHGRALEYHKHDLLLARtigdrmGEAKAS 109
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNP----EAFALLGEILLQLGDLDEAIVLLHEALELDP------DEPEAR 75

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 525313748 110 GNLGNTLKVLGRFDEAAVCCQRHLSIAQEQgdkvgeARALYNIGNVYHAKGK 161
Cdd:COG4783   76 LNLGLALLKAGDYDEALALLEKALKLDPEH------PEAYLRLARAYRALGR 121
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 197-277 1.93e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.43  E-value: 1.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 197 SLVKELGDRAAQGRAYGNLGNTHYLLGNFTEA-TTFhkerLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKT 275
Cdd:COG1729   18 AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAaEAF----EKLLKRYPDSPKAPDALLKLGLSYLELGDYDKARATLEEL 93


                 ..
gi 525313748 276 LQ 277
Cdd:COG1729   94 IK 95
COG3899 COG3899
Predicted ATPase [General function prediction only];
29-428 2.01e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 41.38  E-value: 2.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748   29 LELALE-GERLCKAGDFKTGVAFFEAAVQVGT-------EDLKTLSAIYSQLGNAYFYLKEHGRALEYHKHDLLLARTIG 100
Cdd:COG3899   745 LALLLElAEALYLAGRFEEAEALLERALAARAlaalaalRHGNPPASARAYANLGLLLLGDYEEAYEFGELALALAERLG 824

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  101 DRMGEAKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQEQGDKVGEARALYNIGNVYHAKGKQLSWNAANATQDPGHLPPD 180
Cdd:COG3899   825 DRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAAL 904

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  181 VRETLCKASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHV 260
Cdd:COG3899   905 AAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAA 984

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  261 FLGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYV 340
Cdd:COG3899   985 AAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAA 1064

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  341 SMGRPAQALTFAKKHLQISQEIGDRHGELTARMNVAQLQLVLGRLTSPAASEKPDLAGYEAQGARPKRTQRLSAETWDLL 420
Cdd:COG3899  1065 AAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALAL 1144


                  ....*...
gi 525313748  421 RLPLEREQ 428
Cdd:COG3899  1145 ALAALLLL 1152
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 198-359 2.19e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.17  E-value: 2.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 198 LVKELGDRAAQGRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQ 277
Cdd:COG5010    3 ALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 278 LSRQlrdqavEAQACYSLGNTYTLLQDYERAaeyhLRHLLIAQELADrvGEGRACWSLGNAYVSMGRPAQALTFAKKHLQ 357
Cdd:COG5010   83 LDPN------NPELYYNLALLYSRSGDKDEA----KEYYEKALALSP--DNPNAYSNLAALLLSLGQDDEAKAALQRALG 150


                 ..
gi 525313748 358 IS 359
Cdd:COG5010  151 TS 152
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
219-311 3.05e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 3.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 219 HYLLGNFTEATTFHKERLAIAKEFGDkaaerrAYSNLGNAHVFLGRFDvAAEYYKKTLQLSRQlrdqavEAQACYSLGNT 298
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNAD------ALNNLGLLLLEQGRYD-EAIALEKALKLDPN------NAEALLNLAEL 68

                         90
                 ....*....|...
gi 525313748 299 YTLLQDYERAAEY 311
Cdd:COG3063   69 LLELGDYDEALAY 81
TPR_1 pfam00515
Tetratricopeptide repeat;
106-138 3.70e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 3.70e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 525313748  106 AKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQE 138
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
35-207 4.65e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.22  E-value: 4.65e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748  35 GERLCKAGDFKTGVAFFEAAVQVGTEDlktlSAIYSQLGNAYFYLKEHGRALEYHKHDLLLARtigdrmGEAKASGNLGN 114
Cdd:COG0457   83 GLALQALGRYEEALEDYDKALELDPDD----AEALYNLGLALLELGRYDEAIEAYERALELDP------DDADALYNLGI 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 115 TLKVLGRFDEAAVCCQRHLSIAQEQGDKVGEARALYNIGNVYHAKGKQLSWNAANATQDPGHLPPDVRETLCKASEFYER 194
Cdd:COG0457  153 ALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLA 232

                        170
                 ....*....|...
gi 525313748 195 NLSLVKELGDRAA 207
Cdd:COG0457  233 LRLAALALYQYRA 245
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 289-321 4.98e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 4.98e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 525313748   289 AQACYSLGNTYTLLQDYERAAEYHLRHLLIAQE 321
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 106-138 5.13e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 5.13e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 525313748   106 AKASGNLGNTLKVLGRFDEAAVCCQRHLSIAQE 138
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 219-311 6.27e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.89  E-value: 6.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 525313748 219 HYLLGNFTEA-TTFHKerlaIAKEFGDKAAERRAYSNLGNAHVFLGRFDVAAEYYKKTLQLSrqlRDQAVEAQACYSLGN 297
Cdd:COG1729    3 LLKAGDYDEAiAAFKA----FLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY---PDSPKAPDALLKLGL 75

                         90
                 ....*....|....
gi 525313748 298 TYTLLQDYERAAEY 311
Cdd:COG1729   76 SYLELGDYDKARAT 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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