NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|209364523|ref|NP_001129217|]
View 

alsin isoform 2 [Homo sapiens]

Protein Classification

ATS1 family protein( domain architecture ID 11474102)

ATS1 family protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 39-216 2.20e-26

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


:

Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 108.14  E-value: 2.20e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523  39 GGKTVLQAALGVKHGVLLTEDGEVYSFG----------TLPWRSGPVEICPSSPilenalvgqyVITVATGSFHSGAVTD 108
Cdd:COG5184  147 GLSGVVAIAAGGYHTCALKSDGTVWCWGansygqlgdgTTTDRPTPVQVGGLSG----------VVAVAAGGDHSCALKS 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523 109 NGVAYMWGENSAGQCAVANQQYVPEPNPVSiadseasplLAVRILQLACGEEHTLALSISREIWAWG--TGCQLGLITTA 186
Cdd:COG5184  217 DGTVWCWGSNSSGQLGDGTTTDRATPVQVA---------GLTGVVAIAAGGSHTCALKSDGTVWCWGdnSYGQLGDGTTT 287

                        170       180       190
                 ....*....|....*....|....*....|
gi 209364523 187 fPVTKPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184  288 -DRSTPVKVPGLSG--VVAVAAGSSHTCAL 314
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 39-216 2.20e-26

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 108.14  E-value: 2.20e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523  39 GGKTVLQAALGVKHGVLLTEDGEVYSFG----------TLPWRSGPVEICPSSPilenalvgqyVITVATGSFHSGAVTD 108
Cdd:COG5184  147 GLSGVVAIAAGGYHTCALKSDGTVWCWGansygqlgdgTTTDRPTPVQVGGLSG----------VVAVAAGGDHSCALKS 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523 109 NGVAYMWGENSAGQCAVANQQYVPEPNPVSiadseasplLAVRILQLACGEEHTLALSISREIWAWG--TGCQLGLITTA 186
Cdd:COG5184  217 DGTVWCWGSNSSGQLGDGTTTDRATPVQVA---------GLTGVVAIAAGGSHTCALKSDGTVWCWGdnSYGQLGDGTTT 287

                        170       180       190
                 ....*....|....*....|....*....|
gi 209364523 187 fPVTKPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184  288 -DRSTPVKVPGLSG--VVAVAAGSSHTCAL 314
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
170-216 2.25e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 52.90  E-value: 2.25e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 209364523  170 EIWAWG--TGCQLGLITTAfPVTKPQKVEHLAGRVVLQVACGAFHSLAL 216
Cdd:pfam00415   3 RVYTWGrnDYGQLGLGTTE-NVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
 
Name Accession Description Interval E-value
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 39-216 2.20e-26

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 108.14  E-value: 2.20e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523  39 GGKTVLQAALGVKHGVLLTEDGEVYSFG----------TLPWRSGPVEICPSSPilenalvgqyVITVATGSFHSGAVTD 108
Cdd:COG5184  147 GLSGVVAIAAGGYHTCALKSDGTVWCWGansygqlgdgTTTDRPTPVQVGGLSG----------VVAVAAGGDHSCALKS 216

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523 109 NGVAYMWGENSAGQCAVANQQYVPEPNPVSiadseasplLAVRILQLACGEEHTLALSISREIWAWG--TGCQLGLITTA 186
Cdd:COG5184  217 DGTVWCWGSNSSGQLGDGTTTDRATPVQVA---------GLTGVVAIAAGGSHTCALKSDGTVWCWGdnSYGQLGDGTTT 287

                        170       180       190
                 ....*....|....*....|....*....|
gi 209364523 187 fPVTKPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184  288 -DRSTPVKVPGLSG--VVAVAAGSSHTCAL 314
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 31-216 1.87e-23

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 100.05  E-value: 1.87e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523  31 TPERLPGwgGKTVLQAALGVKHGVLLTEDGEVYSFG----------TLPWRSGPVEIcpssPILENalvgqyVITVATGS 100
Cdd:COG5184   40 TPVRVPG--LSNVVAVAAGGDHTCALKADGTVWCWGnnsygqlgdgTTTDRTTPVKV----PGLTG------VVAVAAGY 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523 101 FHSGAVTDNGVAYMWGENSAGQcaVANQQYVPEPNPVSIADSeaspllAVRILQLACGEEHTLALSISREIWAWG--TGC 178
Cdd:COG5184  108 YHSCALKSDGTVWCWGDNSSGQ--LGDGTTTNRLTPVQVDAG------LSGVVAIAAGGYHTCALKSDGTVWCWGanSYG 179

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 209364523 179 QLGLITTAfPVTKPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184  180 QLGDGTTT-DRPTPVQVGGLSG--VVAVAAGGDHSCAL 214
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 31-219 7.07e-22

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 95.43  E-value: 7.07e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523  31 TPERLPGWGGktVLQAALGVKHGVLLTEDGEVYSFG----------TLPWRSGPVEICPSspiLENalvgqyVITVATGS 100
Cdd:COG5184   90 TPVKVPGLTG--VVAVAAGYYHSCALKSDGTVWCWGdnssgqlgdgTTTNRLTPVQVDAG---LSG------VVAIAAGG 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523 101 FHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSeaspllavrILQLACGEEHTLALSISREIWAWGTG--C 178
Cdd:COG5184  159 YHTCALKSDGTVWCWGANSYGQLGDGTTTDRPTPVQVGGLSG---------VVAVAAGGDHSCALKSDGTVWCWGSNssG 229

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 209364523 179 QLGLITTAFPVTkPQKVEHLAGrvVLQVACGAFHSLAL-----VQC 219
Cdd:COG5184  230 QLGDGTTTDRAT-PVQVAGLTG--VVAIAAGGSHTCALksdgtVWC 272
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 45-216 1.91e-20

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 91.58  E-value: 1.91e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523  45 QAALGVKHGVLLTEDGEVYSFG----------TLPWRSGPVEIcpssPILENalvgqyVITVATGSFHSGAVTDNGVAYM 114
Cdd:COG5184    2 QVAAGGSHSCALKSDGTVWCWGdnsygqlgdgTTTDRSTPVRV----PGLSN------VVAVAAGGDHTCALKADGTVWC 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523 115 WGENSAGQCAVANQQYVPEPNPVSIADSeaspllavrILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAfPVTKP 192
Cdd:COG5184   72 WGNNSYGQLGDGTTTDRTTPVKVPGLTG---------VVAVAAGYYHSCALKSDGTVWCWGDNSsgQLGDGTTT-NRLTP 141

                        170       180
                 ....*....|....*....|....
gi 209364523 193 QKVEHLAGRVVlQVACGAFHSLAL 216
Cdd:COG5184  142 VQVDAGLSGVV-AIAAGGYHTCAL 164
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 94-216 9.13e-18

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 83.49  E-value: 9.13e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523  94 ITVATGSFHSGAVTDNGVAYMWGENSAGQcaVANQQYVPEPNPVSIADSEaspllavRILQLACGEEHTLALSISREIWA 173
Cdd:COG5184    1 TQVAAGGSHSCALKSDGTVWCWGDNSYGQ--LGDGTTTDRSTPVRVPGLS-------NVVAVAAGGDHTCALKADGTVWC 71

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 209364523 174 WGTGC--QLGLITTAFPVTkPQKVEHLAGrvVLQVACGAFHSLAL 216
Cdd:COG5184   72 WGNNSygQLGDGTTTDRTT-PVKVPGLTG--VVAVAAGYYHSCAL 113
ATS1 COG5184
Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, ...
 31-189 1.12e-17

Alpha-tubulin suppressor ATS1 and related RCC1 domain-containing proteins [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 444065 [Multi-domain]  Cd Length: 343  Bit Score: 83.49  E-value: 1.12e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523  31 TPERLPGWGGktVLQAALGVKHGVLLTEDGEVYSFG----------TLPWRSGPVEICPSSPilenalvgqyVITVATGS 100
Cdd:COG5184  191 TPVQVGGLSG--VVAVAAGGDHSCALKSDGTVWCWGsnssgqlgdgTTTDRATPVQVAGLTG----------VVAIAAGG 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 209364523 101 FHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADseaspllavRILQLACGEEHTLALSISREIWAWGTGC-- 178
Cdd:COG5184  259 SHTCALKSDGTVWCWGDNSYGQLGDGTTTDRSTPVKVPGLS---------GVVAVAAGSSHTCALLTDGTVWCWGDNAyg 329

                        170
                 ....*....|....
gi 209364523 179 QLGLITT---AFPV 189
Cdd:COG5184  330 QLGDGTTtdrSTPV 343
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
170-216 2.25e-09

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 52.90  E-value: 2.25e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 209364523  170 EIWAWG--TGCQLGLITTAfPVTKPQKVEHLAGRVVLQVACGAFHSLAL 216
Cdd:pfam00415   3 RVYTWGrnDYGQLGLGTTE-NVLVPQKVEGLSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
93-122 3.41e-06

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 43.18  E-value: 3.41e-06
                          10        20        30
                  ....*....|....*....|....*....|
gi 209364523   93 VITVATGSFHSGAVTDNGVAYMWGENSAGQ 122
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWGDNSYGQ 30
RCC1 pfam00415
Regulator of chromosome condensation (RCC1) repeat;
109-165 2.18e-05

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 395335 [Multi-domain]  Cd Length: 50  Bit Score: 41.35  E-value: 2.18e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 209364523  109 NGVAYMWGENSAGQCAVANQQYVPEPNPVSIadseaspLLAVRILQLACGEEHTLAL 165
Cdd:pfam00415   1 DGRVYTWGRNDYGQLGLGTTENVLVPQKVEG-------LSGNKVVQVACGGDHTVAL 50
RCC1_2 pfam13540
Regulator of chromosome condensation (RCC1) repeat;
152-175 9.03e-03

Regulator of chromosome condensation (RCC1) repeat;


Pssm-ID: 463914 [Multi-domain]  Cd Length: 30  Bit Score: 33.55  E-value: 9.03e-03
                          10        20
                  ....*....|....*....|....
gi 209364523  152 ILQLACGEEHTLALSISREIWAWG 175
Cdd:pfam13540   1 VVSVAAGDNHTLALTSDGRVYCWG 24
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH