|
Name |
Accession |
Description |
Interval |
E-value |
| HkD_Girdin |
cd22229 |
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation ... |
10-165 |
3.85e-90 |
|
Hook domain found in Girdin and similar proteins; Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration.
Pssm-ID: 411800 Cd Length: 156 Bit Score: 289.38 E-value: 3.85e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 10 LEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFY 89
Cdd:cd22229 1 LEQFMSSPLVTWVKTFGPLATGNGTPLDEYVALVDGVFLNEVMLQINPKSSNQRVNKKVNNDASLRIQNLSILVKQIKLY 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 208022632 90 YQETLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22229 81 YQETLQQLIMMSLPNVLVLGRNPLSEQGTEEMKKLLLLLLGCAVQCERKEEFIERIQTLDFDTKAAVAAHIQEVTH 156
|
|
| HkD_Daple |
cd22228 |
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) ... |
13-165 |
1.38e-62 |
|
Hook domain found in Daple (Dvl-associating protein with a high frequency of leucine residues) and similar proteins; Protein Daple, also called coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling.
Pssm-ID: 411799 Cd Length: 153 Bit Score: 210.55 E-value: 1.38e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 13 FMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFYYQE 92
Cdd:cd22228 1 FLQSPLVTWVKTFGPLGFGSEDKLSMYMDLVDGVFLNKIMLQIDPRPTNQRVNKHVNNDVNLRIQNLTILVRHIKTYYQE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 208022632 93 TLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22228 81 VLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKMLLLVLGCAVQCERKEEFIERIKQLDIETQAAIVSHIQEVTH 153
|
|
| HkD_HkRP |
cd22223 |
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, ... |
13-165 |
2.74e-60 |
|
Hook domain found in the Hook-related protein (HkRP) family; The HkRP family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C (CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). It acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein G(i) alpha subunits. It also acts as a guanine nucleotide dissociation inhibitor for guanine nucleotide-binding protein G(s) subunit alpha GNAS. In addition, Girdin plays an essential role in cell migration. Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing. All family members contain a conserved globular Hook domain which folds as a variant of the helical calponin homology (CH) domain.
Pssm-ID: 411794 Cd Length: 149 Bit Score: 203.59 E-value: 2.74e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 13 FMTSPLVTWVKTFgplaAGNGTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLRMHNLSILVRQIKFYYQE 92
Cdd:cd22223 1 FLSSPLVTWAKTF----ADDGSAELSYTDLVDGVFLNNVMLQIDPRPFSEVSNRNVDDDVNARIQNLDLLLRNIKSFYQE 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 208022632 93 TLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22223 77 VLQQLIVMKLPDILTIGREPESEQSLEELEKLLLLLLGCAVQCERKEEFIERIKNLDLEVQHALVACIQEVTD 149
|
|
| HkD_Gipie |
cd22230 |
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar ... |
11-164 |
3.81e-36 |
|
Hook domain found in Gipie (GRP78-interacting protein induced by ER stress) and similar proteins; Gipie, also called coiled-coil domain-containing protein 88B (CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. It acts as a positive regulator of T-cell maturation and inflammatory function. As a microtubule-binding protein, Gipie regulates lytic granule clustering and NK cell killing.
Pssm-ID: 411801 Cd Length: 170 Bit Score: 135.34 E-value: 3.81e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 11 EQFMTSPLVTWVKTF------------GPLAAGNGTNLD---EYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDASLR 75
Cdd:cd22230 1 EEFMSGALVTWALGFeglvgeeedslgFPEEEEEEGTLDaekRFLRLSNGDLLNRVMGIIDPSPRGGPRMRGDDGPAAHR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 76 MHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAA 155
Cdd:cd22230 81 VQNLHILWGRLRDFYQEELQQLILSPPPDLQVMGRDPFTEEAVQELEKLLRLLLGAAVQCERRELFIRHIQGLDLDVQAE 160
|
....*....
gi 208022632 156 VAAHIQEVT 164
Cdd:cd22230 161 LAEAIQEVT 169
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
596-1374 |
1.61e-25 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 115.54 E-value: 1.61e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAE---ELENELHHLEKEneLLQKKITNLKitcEKIEALEQENSELEREN 672
Cdd:TIGR02168 181 LERTRENLDRLEDILNELERQLKSLERQAEKAErykELKAELRELELA--LLVLRLEELR---EELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 673 RKLKKTLdsfKNLTFQLESLEKENSQLDEENLELRRNVESLKCA-SMKMAQLQLENKELESEKEQLKKGLELLKASFKKT 751
Cdd:TIGR02168 256 EELTAEL---QELEEKLEELRLEVSELEEEIEELQKELYALANEiSRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 752 ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:TIGR02168 333 DELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR---SKVAQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 832 KQLEKENKRLRQQAEIKDTTLEENNVKigNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDL 911
Cdd:TIGR02168 410 ERLEDRRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQL 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 912 VSEKLKTQQMNNDLEKLTHELEKIGLNKERL------LHDEQSTDDRYKL-----LESKLESTLKKSLEIKEEKIAALE- 979
Cdd:TIGR02168 488 QARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvLSELISVDEGYEAaieaaLGGRLQAVVVENLNAAKKAIAFLKq 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 980 ------ARLEESTNYNQQLRQELKTVKKNYEA--------------------------------------LKQRQDEERM 1015
Cdd:TIGR02168 568 nelgrvTFLPLDSIKGTEIQGNDREILKNIEGflgvakdlvkfdpklrkalsyllggvlvvddldnalelAKKLRPGYRI 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1016 V-------QSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Cdd:TIGR02168 648 VtldgdlvRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1089 TVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHER 1168
Cdd:TIGR02168 728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1169 QASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM-LLENKNHETVAAEYKKLCGEND 1247
Cdd:TIGR02168 808 LRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELeELIEELESELEALLNERASLEE 887
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1248 RLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLL 1327
Cdd:TIGR02168 888 ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDE 967
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|.
gi 208022632 1328 DQIQTLMLQNRTLLEQ----NMESKDlfhvEQRQYIDKLNELRRQKEKLEE 1374
Cdd:TIGR02168 968 EEARRRLKRLENKIKElgpvNLAAIE----EYEELKERYDFLTAQKEDLTE 1014
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
249-1079 |
1.76e-22 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 105.91 E-value: 1.76e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 249 LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnLLSDARSARMYRDELDALREKavrVDKLESE 328
Cdd:TIGR02168 230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLE---VSELEEEIEELQKELYALANE---ISRLEQQ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 329 VSRYKERLH----DIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDM 400
Cdd:TIGR02168 304 KQILRERLAnlerQLEELEAQLEELESKLDELAEELAELEEKLEELKEEleslEAELEELEAELEELESRLEELEEQLET 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 401 DRKKIEELmEENMTLEMAQKQSMDEslhlgwELEQISRTSELSEAPQKSLGhevNELTSSRLLKLEMENQSLTKTVEELR 480
Cdd:TIGR02168 384 LRSKVAQL-ELQIASLNNEIERLEA------RLERLEDRRERLQQEIEELL---KKLEEAELKELQAELEELEEELEELQ 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 481 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQEN 560
Cdd:TIGR02168 454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDE 533
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 561 EHLNQTVSSLRQRSQ----ISAEARVKDIE--KENKILHESIKE-TSSKLSKIEFEKRQIKKELEHYKEKGERAEELENE 633
Cdd:TIGR02168 534 GYEAAIEAALGGRLQavvvENLNAAKKAIAflKQNELGRVTFLPlDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK 613
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 634 LHhlekenELLQKKITNLKITCEKIEALEQENsELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESL 713
Cdd:TIGR02168 614 LR------KALSYLLGGVLVVDDLDNALELAK-KLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKI 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKasfKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEmen 793
Cdd:TIGR02168 687 EELEEKIAELEKALAELRKELEELEEELEQLR---KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELE--- 760
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 794 qtlqknlEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Cdd:TIGR02168 761 -------AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEklktqqmnndLEKLTHELEKIGLNKERLLHDEQSTDDRY 953
Cdd:TIGR02168 834 AATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE----------LEALLNERASLEEALALLRSELEELSEEL 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 954 KLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELktvkknyeALKQRQDEERMVQSSPPISGEDNKWERES 1033
Cdd:TIGR02168 904 RELESKR-SELRRELEELREKLAQLELRLEGLEVRIDNLQERL--------SEEYSLTLEEAEALENKIEDDEEEARRRL 974
|
810 820 830 840
....*....|....*....|....*....|....*....|....*.
gi 208022632 1034 QETTRELlkvkDRLIEVernNATLQAEKQALKTQLKQLETQNNNLQ 1079
Cdd:TIGR02168 975 KRLENKI----KELGPV---NLAAIEEYEELKERYDFLTAQKEDLT 1013
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
462-1299 |
7.76e-22 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 103.60 E-value: 7.76e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 462 LLKLEMENQSLTK---TVEELRTTVDSVEGNASKILK-MEKENQRLSKKVEILENEIVQEKQSLQNcqnlSKDLMKEKAQ 537
Cdd:TIGR02168 178 ERKLERTRENLDRledILNELERQLKSLERQAEKAERyKELKAELRELELALLVLRLEELREELEE----LQEELKEAEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 538 LEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKEL 617
Cdd:TIGR02168 254 ELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY-ALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKL 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 618 EHYKEkgeRAEELENELHHLEKENELLQKKITNLKITCEKIEALEQE-NSELERENRKLKKTLDSFKNLTFQLESLEKEN 696
Cdd:TIGR02168 333 DELAE---ELAELEEKLEELKEELESLEAELEELEAELEELESRLEElEEQLETLRSKVAQLELQIASLNNEIERLEARL 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 697 SQLDEENLELRRNVESLKcasmkMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN 776
Cdd:TIGR02168 410 ERLEDRRERLQQEIEELL-----KKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRL--------EQLEKENK---SLE---QETSQ--LEKDKKQLEKENKR 840
Cdd:TIGR02168 485 AQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvlsELISVDEGyeaAIEaalGGRLQavVVENLNAAKKAIAF 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 841 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKEnkelVKRATIDIKTLVTLREDLvseklktQQ 920
Cdd:TIGR02168 565 LKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPK----LRKALSYLLGGVLVVDDL-------DN 633
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 921 MNNDLEKLTHELEKIGLNKERLLHD----EQSTDDRYKLLESKLE-STLKKSLEIKEEKIAALEARLEESTNYNQQLRQE 995
Cdd:TIGR02168 634 ALELAKKLRPGYRIVTLDGDLVRPGgvitGGSAKTNSSILERRREiEELEEKIEELEEKIAELEKALAELRKELEELEEE 713
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 996 LKTVKKNYEALKQ------------RQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQA 1063
Cdd:TIGR02168 714 LEQLRKELEELSRqisalrkdlarlEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1064 LKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQStslmnqnaqlliqqSSLENENESVIK 1143
Cdd:TIGR02168 794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI--------------EELSEDIESLAA 859
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1144 EREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEdlekmLKVEQE 1223
Cdd:TIGR02168 860 EIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLE-----LRLEGL 934
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 208022632 1224 KMLLENKNhETVAAEYKKLCGENDRLnhtYSQLLKETEVLQTDHKNLKSLLNNskLEQTRLEA--EFSKLKEQYQQLD 1299
Cdd:TIGR02168 935 EVRIDNLQ-ERLSEEYSLTLEEAEAL---ENKIEDDEEEARRRLKRLENKIKE--LGPVNLAAieEYEELKERYDFLT 1006
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
610-1223 |
7.88e-22 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 103.22 E-value: 7.88e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 610 KRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNLTFQL 689
Cdd:PRK03918 171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEIS---SELPELREELEKLEKEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 690 ESLEKENSQLDEENLELRRNVESLKcasmkmaqlqLENKELESEKEQLKKglelLKASFKKTERLEVSYQGLDIENQRLQ 769
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELK----------KEIEELEEKVKELKE----LKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 770 KTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEK------ENKSLEQETSQLEKDKKQLEKEN-KRLR 842
Cdd:PRK03918 314 KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEErhelyeEAKAKKEELERLKKRLTGLTPEKlEKEL 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 843 QQAEIKDTTLEEN----NVKIGNLEKENKTLSKEIGIYKES------CVRLKElEKENKELVKRATIDIKtlvtlreDLV 912
Cdd:PRK03918 394 EELEKAKEEIEEEiskiTARIGELKKEIKELKKAIEELKKAkgkcpvCGRELT-EEHRKELLEEYTAELK-------RIE 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 913 SEKLKTQQMNNDLEKLTHELEKIgLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEEstnynqqL 992
Cdd:PRK03918 466 KELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIK-------L 537
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 993 RQELKTVKKNYEALKQRQDEERMVqssppisgednkwERESQETTRELLKVKDRLIEVERNNAtlqaekQALKTQLKQLE 1072
Cdd:PRK03918 538 KGEIKSLKKELEKLEELKKKLAEL-------------EKKLDELEEELAELLKELEELGFESV------EELEERLKELE 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1073 tqnnnlqaqilALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLmnqnaqlliqqSSLENENESVIKEREDLKSLY 1152
Cdd:PRK03918 599 -----------PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEEL-----------AETEKRLEELRKELEELEKKY 656
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 208022632 1153 DSliKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQE 1223
Cdd:PRK03918 657 SE--EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEE 725
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
517-1204 |
1.86e-20 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 98.55 E-value: 1.86e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 517 EKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEaRVKDIEKENKILHESI 596
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKD-KINKLNSDLSKINSEI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 597 KETSSKLSKIEFEKRQIKKELEHYKEKgerAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLK 676
Cdd:TIGR04523 113 KNDKEQKNKLEVELNKLEKQKKENKKN---IDKFLTEIKKKEKELEKLNNKYNDLK---KQKEELENELNLLEKEKLNIQ 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 677 KTLDSFKN-------LTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLKKGLELLKASFK 749
Cdd:TIGR04523 187 KNIDKIKNkllklelLLSNLKKKIQKNKSLESQISELKKQNNQLK------DNIEKKQQEINEKTTEISNTQTQLNQLKD 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEME-NQTLQKNL-EELKISSKRLEQLEKENKSLEQETSQL 827
Cdd:TIGR04523 261 EQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQkEQDWNKELkSELKNQEKKLEEIQNQISQNNKIISQL 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 828 EKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:TIGR04523 341 NEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 908 REDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLE---STLKKSLEIKEEKIAALEARLEE 984
Cdd:TIGR04523 421 KELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSrsiNKIKQNLEQKQKELKSKEKELKK 500
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 985 STNYNQQLRQELKTVKKNYEALKQRQD--EERMVQSSPPISGEDNKWERESQETTRELLK-----VKDRLIEVERNNATL 1057
Cdd:TIGR04523 501 LNEEKKELEEKVKDLTKKISSLKEKIEklESEKKEKESKISDLEDELNKDDFELKKENLEkeideKNKEIEELKQTQKSL 580
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1058 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1137
Cdd:TIGR04523 581 KKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNK 660
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1138 NESVIKEREDLKSLYDSLI---KDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL 1204
Cdd:TIGR04523 661 WPEIIKKIKESKTKIDDIIelmKDWLKELSLHYKKYITRMIRIKDLPKLEEKYKEIEKELKKLDEFSKEL 730
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
571-1072 |
1.87e-20 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 98.60 E-value: 1.87e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 571 RQRSQISAEARVKDIEKENK-----ILHEsIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQ 645
Cdd:PRK03918 180 RLEKFIKRTENIEELIKEKEkeleeVLRE-INEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 646 KKITNLKitcEKIEALEQENSELERENRKLKK---------TLDSFKNLTFQ-LESLEKENSQLDEENLELRRNVESLKC 715
Cdd:PRK03918 259 EKIRELE---ERIEELKKEIEELEEKVKELKElkekaeeyiKLSEFYEEYLDeLREIEKRLSRLEEEINGIEERIKELEE 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 716 ASMKMAQLQLENKELESEKEQLKKGLELL---KASFKKTERLEVSYQGLDIEN-----QRLQKTLENSNKKIQQLESELQ 787
Cdd:PRK03918 336 KEERLEELKKKLKELEKRLEELEERHELYeeaKAKKEELERLKKRLTGLTPEKlekelEELEKAKEEIEEEISKITARIG 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 788 DLEMENQTLQKNLEELKIS-----------------------SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:PRK03918 416 ELKKEIKELKKAIEELKKAkgkcpvcgrelteehrkelleeyTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESEL 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 845 AEIKDTT-----------------LEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKratidiktlvtl 907
Cdd:PRK03918 496 IKLKELAeqlkeleeklkkynleeLEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEK------------ 563
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 908 redlvseklKTQQMNNDLEKLTHELEKIGLNkerllhDEQSTDDRYKLLESKLESTL-----KKSLEIKEEKIAALEARL 982
Cdd:PRK03918 564 ---------KLDELEEELAELLKELEELGFE------SVEELEERLKELEPFYNEYLelkdaEKELEREEKELKKLEEEL 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 983 EESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQssppISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQ 1062
Cdd:PRK03918 629 DKAFEELAETEKRLEELRKELEELEKKYSEEEYEE----LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELE 704
|
570
....*....|
gi 208022632 1063 ALKTQLKQLE 1072
Cdd:PRK03918 705 EREKAKKELE 714
|
|
| HkD_SF |
cd22211 |
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ... |
16-165 |
3.60e-20 |
|
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.
Pssm-ID: 411792 Cd Length: 145 Bit Score: 88.87 E-value: 3.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 16 SPLVTWVKTFGPLaagngTNLDEYVALVDGVFLNQVMLQINPKLESQRVNKKVNNDAS--LRMHNLSILVRQIKFYYQET 93
Cdd:cd22211 2 AALLAWINTFPLS-----SPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSSDNwvLKLNNLKKLYRSLSKYYREV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 208022632 94 LQQLIM-MSLPNVLIIGKNPfseqGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTH 165
Cdd:cd22211 77 LGQQLSdLPLPDLSAIARDG----DEEEIVKLLELVLGAAVQCENKEEYIARIQQLDESTQAELMLIIQEVLE 145
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
476-1269 |
5.40e-20 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 97.45 E-value: 5.40e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 476 VEELRTTVDSVEGNASKILKMEKENQRLSK-KVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK 554
Cdd:TIGR02169 193 IDEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 555 ILEQENEHlnqtVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEkgeRAEELENEL 634
Cdd:TIGR02169 273 LLEELNKK----IKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA---EIEELEREI 345
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 635 HHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKnltfqlESLEKENSQLDEENLELRRNVESLK 714
Cdd:TIGR02169 346 EEERKRRDKLTEEYAELK---EELEDLRAELEEVDKEFAETRDELKDYR------EKLEKLKREINELKRELDRLQEELQ 416
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 715 CASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERlevsyqgldiENQRLQKTLENSNKKIQQLESELQDLEMENQ 794
Cdd:TIGR02169 417 RLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEW----------KLEQLAADLSKYEQELYDLKEEYDRVEKELS 486
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 795 TLQKNLEELKISSKRLEQLEKENKSLEQE-----------TSQLEKDKKQL-----------------------EKENKR 840
Cdd:TIGR02169 487 KLQRELAEAEAQARASEERVRGGRAVEEVlkasiqgvhgtVAQLGSVGERYataievaagnrlnnvvveddavaKEAIEL 566
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 841 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIykesCVRLKELEKENKELVK---------------RATIDIKTLV 905
Cdd:TIGR02169 567 LKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGF----AVDLVEFDPKYEPAFKyvfgdtlvvedieaaRRLMGKYRMV 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 906 TLREDLV---------------------SEKLKTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDRYKLLE--SKLES 962
Cdd:TIGR02169 643 TLEGELFeksgamtggsraprggilfsrSEPAELQRLRERLEGLKRELSSL---QSELRRIENRLDELSQELSdaSRKIG 719
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 963 TLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQR-----------QDEERMVQSSPPISGEDNKwER 1031
Cdd:TIGR02169 720 EIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARieeleedlhklEEALNDLEARLSHSRIPEI-QA 798
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1032 ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENS 1111
Cdd:TIGR02169 799 ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALR 878
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1112 TLnsqstslmnqnaqlliqqsslenenesvIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLE 1191
Cdd:TIGR02169 879 DL----------------------------ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALE 930
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1192 VEHRDLEDRYNQLLKQKGQLEDLEKM----LKVEQEKMLLENKN------HETVAAEYKKLCGENDRLNHTYSQLLKETE 1261
Cdd:TIGR02169 931 EELSEIEDPKGEDEEIPEEELSLEDVqaelQRVEEEIRALEPVNmlaiqeYEEVLKRLDELKEKRAKLEEERKAILERIE 1010
|
....*...
gi 208022632 1262 VLQTDHKN 1269
Cdd:TIGR02169 1011 EYEKKKRE 1018
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
253-890 |
4.56e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 94.36 E-value: 4.56e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLlsdarsarmyRDELDALREKavrVDKLESEVSRY 332
Cdd:PRK03918 167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEI----------SSELPELREE---LEKLEKEVKEL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 333 KERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEnlqlkaklhdmemerdmdRKKIEELMEEN 412
Cdd:PRK03918 234 EELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE------------------LKELKEKAEEY 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 413 MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLghevnELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgnasK 492
Cdd:PRK03918 296 IKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKEL-----EEKEERLEELKKKLKELEKRLEELEERHELYE----E 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 493 ILKMEKENQRLSKKVEILENEIVQEKQslqncqnlsKDLMKEKAQLEKTIETLREnserQIKILEQENEHLNQTVSSLRQ 572
Cdd:PRK03918 367 AKAKKEELERLKKRLTGLTPEKLEKEL---------EELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEELKK 433
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 573 RSQISAEARVKDIEKENKilhESIKETSSKLSKIEFEKrqikkelehyKEKGERAEELENELHHLEKENElLQKKITNLK 652
Cdd:PRK03918 434 AKGKCPVCGRELTEEHRK---ELLEEYTAELKRIEKEL----------KEIEEKERKLRKELRELEKVLK-KESELIKLK 499
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 653 ITCEKIEALEQENS-----ELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQL--QL 725
Cdd:PRK03918 500 ELAEQLKELEEKLKkynleELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELlkEL 579
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 726 ENKELESEKEqLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMenqtLQKNLEEL-- 803
Cdd:PRK03918 580 EELGFESVEE-LEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEE----LRKELEELek 654
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKeIGIYKESCVRL 883
Cdd:PRK03918 655 KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALER-VEELREKVKKY 733
|
....*..
gi 208022632 884 KELEKEN 890
Cdd:PRK03918 734 KALLKER 740
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
181-814 |
5.10e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 93.98 E-value: 5.10e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 181 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHflphasssaqspcgspgmKRTESRQHLSVELADAKAKI 260
Cdd:PRK03918 186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------------------KEVKELEELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsarmyRDELDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:PRK03918 248 ESLEGSKRKLEEKIRELEERIEELKKEIEELEEK--------------VKELKELKEKAEEYIKLSEFYEEYLDELREIE 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 341 fykarveelkednqvllETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEmerdmdrKKIEELMEENMTLEMAqK 420
Cdd:PRK03918 314 -----------------KRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELE-------KRLEELEERHELYEEA-K 368
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 421 QSMDESLHL-----GWELEQISRTSELSEAPQKSLGHEVNELTsSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILK 495
Cdd:PRK03918 369 AKKEELERLkkrltGLTPEKLEKELEELEKAKEEIEEEISKIT-ARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTE 447
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 496 MEKENQRLSKKVEIleneivqekqslqncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENE--HLNQTVSSLRQR 573
Cdd:PRK03918 448 EHRKELLEEYTAEL-------------------KRIEKELKEIEEKERKLRKELRELEKVLKKESEliKLKELAEQLKEL 508
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 574 SQISAEARVKDIEKENkilhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PRK03918 509 EEKLKKYNLEELEKKA----EEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGF 584
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 654 TCekIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEenlelrrnveslkcASMKMAQLQLENKELESE 733
Cdd:PRK03918 585 ES--VEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDK--------------AFEELAETEKRLEELRKE 648
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 734 KEQLKKglellKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL 813
Cdd:PRK03918 649 LEELEK-----KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERV 723
|
.
gi 208022632 814 E 814
Cdd:PRK03918 724 E 724
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-904 |
9.75e-19 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 93.59 E-value: 9.75e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARmyrdelDALREKAVRVDKLESEVSR 331
Cdd:TIGR02169 288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------REIEEERKRRDKLTEEYAE 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 332 YKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRarsDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR02169 362 LKEELEDLR---AELEEVDKEFAETRDELKDYREKLEKLK---REINELKRELDRLQEELQRLSEELADLNAAIAGIEAK 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRTTV-------- 483
Cdd:TIGR02169 436 INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV-EKELSKLQRELAEAEAQARASEERVrggravee 514
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 484 ---DSVEGNASKILKMEKENQRLSKKVEI-----LENEIVQEKQSLQNCQNLSKDL---------MKEKAQLEKTIETLR 546
Cdd:TIGR02169 515 vlkASIQGVHGTVAQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKEAIELLKRRkagratflpLNKMRDERRDLSILS 594
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 547 ENSERQIKI-------------------------LEQENEHLNQ-----------------TVSSLRQRSQISAEARVKD 584
Cdd:TIGR02169 595 EDGVIGFAVdlvefdpkyepafkyvfgdtlvvedIEAARRLMGKyrmvtlegelfeksgamTGGSRAPRGGILFSRSEPA 674
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 585 IEKEnkiLHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE----ELENELHHLEKENELLQKKITNLKitcEKIEA 660
Cdd:TIGR02169 675 ELQR---LRERLEGLKRELSSLQSELRRIENRLDELSQELSDASrkigEIEKEIEQLEQEEEKLKERLEELE---EDLSS 748
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 661 LEQENSELEREnrklkktldsfknltfqLESLEKENSQLDEENLELRRNVESLKcASMKMAQLQLENKELESEKEQLKKG 740
Cdd:TIGR02169 749 LEQEIENVKSE-----------------LKELEARIEELEEDLHKLEEALNDLE-ARLSHSRIPEIQAELSKLEEEVSRI 810
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 741 LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSL 820
Cdd:TIGR02169 811 EARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE---AALRDLESRLGDL 887
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 821 EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELvKRATID 900
Cdd:TIGR02169 888 KKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAEL-QRVEEE 966
|
....
gi 208022632 901 IKTL 904
Cdd:TIGR02169 967 IRAL 970
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
497-1281 |
2.11e-18 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 92.34 E-value: 2.11e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLnqtvSSLRQRSQI 576
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLN----EERIDLLQE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 656
Cdd:pfam02463 245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 657 KIEALEQENSELERENRKLKKTLD----SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELE- 731
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEikreAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEe 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 732 ---SEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTlqKNLEELKISSK 808
Cdd:pfam02463 405 keaQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE--DLLKETQLVKL 482
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKES--CVRLKEL 886
Cdd:pfam02463 483 QEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVsaTADEVEE 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 887 EKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKK 966
Cdd:pfam02463 563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 967 SLEIKEEKIAALEARLEESTNYNQQL---RQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKV 1043
Cdd:pfam02463 643 AKESGLRKGVSLEEGLAEKSEVKASLselTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1044 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1123
Cdd:pfam02463 723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1124 NAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELlhERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQ 1203
Cdd:pfam02463 803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELK--EEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 208022632 1204 LLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQ 1281
Cdd:pfam02463 881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
594-1374 |
2.45e-18 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 92.05 E-value: 2.45e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 594 ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNlkitcEKIEALEQENSELERENR 673
Cdd:TIGR02169 180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALE-----RQKEAIERQLASLEEELE 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 674 KLKKTLDSF-KNLTFQLESLEKENSQL----DEENLELRRNVESLKcASMKMAQLQLENKELESEK--EQLKKGLELLKA 746
Cdd:TIGR02169 255 KLTEEISELeKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELE-AEIASLERSIAEKERELEDaeERLAKLEAEIDK 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 747 SFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQknlEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR02169 334 LLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR---DELKDYREKLEKLKREINELKRELDR 410
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 827 LEKDKKQLEKENKRLRQQAEIK-------DTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKE----LEKENKELVK 895
Cdd:TIGR02169 411 LQEELQRLSEELADLNAAIAGIeakinelEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEeydrVEKELSKLQR 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 896 RATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKER-LLHDEQSTDDRYKLLESKLESTLKKSLEI-KEE 973
Cdd:TIGR02169 491 ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyATAIEVAAGNRLNNVVVEDDAVAKEAIELlKRR 570
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 974 KIAAL------EARLEES-----------------TNYNQQLRQELK------TVKKNYEALKQRQDEERMV-------Q 1017
Cdd:TIGR02169 571 KAGRAtflplnKMRDERRdlsilsedgvigfavdlVEFDPKYEPAFKyvfgdtLVVEDIEAARRLMGKYRMVtlegelfE 650
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1018 SSPPISGEDNKWERESQETTR---ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1094
Cdd:TIGR02169 651 KSGAMTGGSRAPRGGILFSRSepaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQ 730
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1095 QNTTLQTQNAKLQVEnstLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLikDHEKLELLhERQASEye 1174
Cdd:TIGR02169 731 EEEKLKERLEELEED---LSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARL--SHSRIPEI-QAELSK-- 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1175 sliskhgtLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEkmLLENKNhetvaaeyKKLCGENDRLNHTYS 1254
Cdd:TIGR02169 803 --------LEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI--DLKEQI--------KSIEKEIENLNGKKE 864
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1255 QLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLD------ 1328
Cdd:TIGR02169 865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDpkgede 944
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1329 --------------QIQTLMLQNRTLLEQNMESKDLFHVEQRQYidklNELRRQKEKLEE 1374
Cdd:TIGR02169 945 eipeeelsledvqaELQRVEEEIRALEPVNMLAIQEYEEVLKRL----DELKEKRAKLEE 1000
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
465-895 |
5.65e-18 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 90.46 E-value: 5.65e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 465 LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQ-LEKTIE 543
Cdd:TIGR04523 234 IEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQdWNKELK 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 544 TLRENSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK-- 621
Cdd:TIGR04523 314 SELKNQEKKLEEIQNQISQNNKIISQLNEQIS-QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLEsq 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 622 ---------EKGERAEELENELHHLEKENELLQKKITNLKITCEK----IEALEQENSELERENRKLKKTLDSFKNltfQ 688
Cdd:TIGR04523 393 indleskiqNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKnnseIKDLTNQDSVKELIIKNLDNTRESLET---Q 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 689 LESLEKEnsqLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKterlevsyqgLDIENQRL 768
Cdd:TIGR04523 470 LKVLSRS---INKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEK----------LESEKKEK 536
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 769 QKTLENSNKKIQQLESELQDLEMENQTLQKNleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIK 848
Cdd:TIGR04523 537 ESKISDLEDELNKDDFELKKENLEKEIDEKN--------KEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEK 608
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 208022632 849 DTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVK 895
Cdd:TIGR04523 609 EKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
350-1058 |
3.23e-17 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 88.64 E-value: 3.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 350 KEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQ-----LKAKLHDMEMERDmdrkkieelmeenmtlEMAQKQsmd 424
Cdd:pfam15921 73 KEHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRqsvidLQTKLQEMQMERD----------------AMADIR--- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 425 eslhlgweleqiSRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKtVEELRTTVDSVEGNASKILKMEKENQRLS 504
Cdd:pfam15921 134 ------------RRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ-IEQLRKMMLSHEGVLQEIRSILVDFEEAS 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 505 KKvEILENEIVQEKQSLQNCQNLSKDLMKEKAQL----------EKTIETLRENSERQIK-ILEQENEHLNQTVSS---- 569
Cdd:pfam15921 201 GK-KIYEHDSMSTMHFRSLGSAISKILRELDTEIsylkgrifpvEDQLEALKSESQNKIElLLQQHQDRIEQLISEheve 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 570 ---LRQRSQiSAEARVKDIEKENKILHESIKETSS----KLSKIEFEKRQIKKELEHYKEKGE-RAEELE-------NEL 634
Cdd:pfam15921 280 itgLTEKAS-SARSQANSIQSQLEIIQEQARNQNSmymrQLSDLESTVSQLRSELREAKRMYEdKIEELEkqlvlanSEL 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 635 HHLEKENELLQKKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLTFQLESLEKEnsqLDEENLELRRNVESL 713
Cdd:pfam15921 359 TEARTERDQFSQESGNLDDQLQKLLAdLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRE---LDDRNMEVQRLEALL 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 714 KC--------ASMKMAQLQLENK----------ELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS 775
Cdd:pfam15921 436 KAmksecqgqMERQMAAIQGKNEslekvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEAT 515
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 776 NKKIQQLES-------ELQDLEMEN---QTLQKNLEELKIS----SKRLEQLEKENKSLEQETSQ-------LEKDKKQL 834
Cdd:pfam15921 516 NAEITKLRSrvdlklqELQHLKNEGdhlRNVQTECEALKLQmaekDKVIEILRQQIENMTQLVGQhgrtagaMQVEKAQL 595
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 835 EKE--NKRLRQQ-----AEIKDTTLEENNVKIGNLEKENKTLskeIGIYKESCVRLKELEKENKELVKRATIDIKTLVTL 907
Cdd:pfam15921 596 EKEinDRRLELQefkilKDKKDAKIRELEARVSDLELEKVKL---VNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSL 672
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 908 REDLvsEKLKtQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLES------KLESTLKKSLEIKEEKIAALEAR 981
Cdd:pfam15921 673 SEDY--EVLK-RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGsdghamKVAMGMQKQITAKRGQIDALQSK 749
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 208022632 982 LeestnynQQLRQELKTVKKNYEALKqrQDEERMVQSSPPISGEDNKW--ERESQETTRELLKVKDRLIEVERNNATLQ 1058
Cdd:pfam15921 750 I-------QFLEEAMTNANKEKHFLK--EEKNKLSQELSTVATEKNKMagELEVLRSQERRLKEKVANMEVALDKASLQ 819
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
701-1014 |
3.51e-17 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 88.07 E-value: 3.51e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 701 EENL--------ELRRNVESLKcasmKMAQLQLENKELESEKEQLKKGLELLKASFKKTE--RLEVSYQGLDIENQRLQK 770
Cdd:COG1196 185 EENLerledilgELERQLEPLE----RQAEKAERYRELKEELKELEAELLLLKLRELEAEleELEAELEELEAELEELEA 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 771 TLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT 850
Cdd:COG1196 261 ELAELEAELEELRLELEELELELEEAQAEEYELL---AELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEE 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 851 TLEENNVKIGNLEKENKTLSKEigiykescvrLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTH 930
Cdd:COG1196 338 ELEELEEELEEAEEELEEAEAE----------LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 931 ELEKIGLNKERLLhDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQ 1010
Cdd:COG1196 408 AEEALLERLERLE-EELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486
|
....
gi 208022632 1011 DEER 1014
Cdd:COG1196 487 AEAA 490
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-1011 |
4.17e-17 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 88.20 E-value: 4.17e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnMNLLSDARSARMYRDeldaLREKAVRVDKLESEVSR 331
Cdd:TIGR02169 238 QKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKK-IKDLGEEEQLRVKEK----IGELEAEIASLERSIAE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 332 YKERLHDIEfykARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenlQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:TIGR02169 313 KERELEDAE---ERLAKLEAEIDKLLAEIEELEREIEEERKRRD----------KLTEEYAELKEELEDLRAELEEVDKE 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 412 NMTLEMAQKQSMDESLHLGWELEQISRTselseapQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRTTVDSVegnAS 491
Cdd:TIGR02169 380 FAETRDELKDYREKLEKLKREINELKRE-------LDRLQEELQRL-SEELADLNAAIAGIEAKINELEEEKEDK---AL 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE---RQIKILEQENEHLNQTVS 568
Cdd:TIGR02169 449 EIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggrAVEEVLKASIQGVHGTVA 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 569 SL---RQRSQISAE----ARVKDIEKENKILHESIKE--TSSKLSKIEF----EKRQIKKELEHYKEKG----------- 624
Cdd:TIGR02169 529 QLgsvGERYATAIEvaagNRLNNVVVEDDAVAKEAIEllKRRKAGRATFlplnKMRDERRDLSILSEDGvigfavdlvef 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 625 ---------------------ERAEELENELHHLEKENELLQK-------------KITNLKITCEKIEALEQENSELER 670
Cdd:TIGR02169 609 dpkyepafkyvfgdtlvvediEAARRLMGKYRMVTLEGELFEKsgamtggsraprgGILFSRSEPAELQRLRERLEGLKR 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 671 ENRKLKKTLDSFKNLTFQLESLEKENSQldeENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFKK 750
Cdd:TIGR02169 689 ELSSLQSELRRIENRLDELSQELSDASR---KIGEIEKEIEQLE---QEEEKLKERLEELEEDLSSLEQEIENVKSELKE 762
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 751 TERlEVSYQGLDIENqrLQKTLEN-----SNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETS 825
Cdd:TIGR02169 763 LEA-RIEELEEDLHK--LEEALNDlearlSHSRIPEIQAELSKLEEEVSRIEARLREIE---QKLNRLTLEKEYLEKEIQ 836
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKeigiykescvRLKELEKENKElvkratidiktlv 905
Cdd:TIGR02169 837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES----------RLGDLKKERDE------------- 893
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 906 tLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLkkSLEIKEEKIAALEARLEES 985
Cdd:TIGR02169 894 -LEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEEL--SLEDVQAELQRVEEEIRAL 970
|
810 820
....*....|....*....|....*.
gi 208022632 986 TNYNQQLRQELKTVKKNYEALKQRQD 1011
Cdd:TIGR02169 971 EPVNMLAIQEYEEVLKRLDELKEKRA 996
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
136-839 |
5.33e-17 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 87.82 E-value: 5.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 136 QKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENvfdlqwmevTDMSQEDIEPLLKNMALHLKRLIDERDEHSETIIELS 215
Cdd:TIGR02169 272 QLLEELNKKIKDLGEEEQLRVKEKIGELEAEIAS---------LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 216 EERDGLHFLPHASSSAQSpcgspgmKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEN 295
Cdd:TIGR02169 343 REIEEERKRRDKLTEEYA-------ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEEL 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 296 MNLLSDARSARMyrdELDALREKavrVDKLESEVsrykerlhdiefyKARVEELKEDNQVLLETKTMLEDQLEGTRARSD 375
Cdd:TIGR02169 416 QRLSEELADLNA---AIAGIEAK---INELEEEK-------------EDKALEIKKQEWKLEQLAADLSKYEQELYDLKE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 376 KLHELEKENLQLKAKLHDMEMERD------MDRKKIEELMEENMT---LEMAQKQSMDESLHLGWEL------------- 433
Cdd:TIGR02169 477 EYDRVEKELSKLQRELAEAEAQARaseervRGGRAVEEVLKASIQgvhGTVAQLGSVGERYATAIEVaagnrlnnvvved 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 434 -------------EQISRTSEL------SEAPQKSLGHE------------------------------VNELTSS---- 460
Cdd:TIGR02169 557 davakeaiellkrRKAGRATFLplnkmrDERRDLSILSEdgvigfavdlvefdpkyepafkyvfgdtlvVEDIEAArrlm 636
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 461 ---RLLKLE---------MENQSLTKTVEELRTTVD--SVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Cdd:TIGR02169 637 gkyRMVTLEgelfeksgaMTGGSRAPRGGILFSRSEpaELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR 716
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 527 LSKDLMKEKAQLEKTIETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKI----LHESIKET 599
Cdd:TIGR02169 717 KIGEIEKEIEQLEQEEEKLKErleELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLearlSHSRIPEI 796
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 600 SSKLSKIEFEKRQIKKelehykekgeRAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTL 679
Cdd:TIGR02169 797 QAELSKLEEEVSRIEA----------RLREIEQKLNRLTLEKEYLEKEIQELQ---EQRIDLKEQIKSIEKEIENLNGKK 863
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 680 DSFKNltfQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQ 759
Cdd:TIGR02169 864 EELEE---ELEELEAALRDLESRLGDLKKERDELE---AQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIE 937
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 760 ---GLDIENQRLQKTLENSNKKIQQLESELQDLEMENqtlQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR02169 938 dpkGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVN---MLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
|
...
gi 208022632 837 ENK 839
Cdd:TIGR02169 1015 KKR 1017
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
325-935 |
1.48e-16 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 86.27 E-value: 1.48e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 325 LESEVSRYK--ERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDR 402
Cdd:PRK03918 141 LESDESREKvvRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELR 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 403 KKIEELMEENMTLEmaqkqsmdeslHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRtt 482
Cdd:PRK03918 221 EELEKLEKEVKELE-----------ELKEEIEELEKELESLEGSKRKLEEKIREL-EERIEELKKEIEELEEKVKELK-- 286
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 483 vdSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKtIETLRENSERQIKILEQENEH 562
Cdd:PRK03918 287 --ELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHEL 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 563 LNQTVSSLRQRSQISA----------EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELEN 632
Cdd:PRK03918 364 YEEAKAKKEELERLKKrltgltpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGR 443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 633 ELHHlEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEkensQLDEENLELRR-NVE 711
Cdd:PRK03918 444 ELTE-EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAE----QLKELEEKLKKyNLE 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 712 SLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN-KKIQQLESELQDLE 790
Cdd:PRK03918 519 ELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELE 598
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 791 menqTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKigNLEKENKTLS 870
Cdd:PRK03918 599 ----PFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYE--ELREEYLELS 672
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 208022632 871 KEIGIYKEscvRLKELEKENKELVKratiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:PRK03918 673 RELAGLRA---ELEELEKRREEIKK----TLEKLKEELEEREKAKKELEKLEKALERVEELREKV 730
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
497-1072 |
2.90e-16 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 85.37 E-value: 2.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQ--RS 574
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARleQD 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEhykEKGERAEELENELHHLEKENELLQKKITnlkit 654
Cdd:COG1196 304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELE---EAEEELEEAEAELAEAEEALLEAEAELA----- 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 655 cEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEK 734
Cdd:COG1196 376 -EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELE------EEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQT--LQKNLEELKISSKRLEQ 812
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkAALLLAGLRGLAGAVAV 528
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 813 LEKENKSLEQ---------------ETSQLEKDKKQLEKENKRLR----QQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Cdd:COG1196 529 LIGVEAAYEAaleaalaaalqnivvEDDEVAAAAIEYLKAAKAGRatflPLDKIRARAALAAALARGAIGAAVDLVASDL 608
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRY 953
Cdd:COG1196 609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 954 KLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGED-NKWERE 1032
Cdd:COG1196 689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDlEELERE 768
|
570 580 590 600
....*....|....*....|....*....|....*....|....*..
gi 208022632 1033 SQETTRELlkvkDRLIEVernN-------ATLQAEKQALKTQLKQLE 1072
Cdd:COG1196 769 LERLEREI----EALGPV---NllaieeyEELEERYDFLSEQREDLE 808
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
252-1074 |
3.79e-16 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 85.12 E-value: 3.79e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQME---IELKRLQQENMNLLSDA-----RSARMYRDELDALREKAVRVD 323
Cdd:TIGR02169 178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAEryqALLKEKREYEGYELLKEkealeRQKEAIERQLASLEEELEKLT 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 324 KLESE-VSRYKERLHDIEFYKARVEELKEDNQVLLETKtMLEDQLEGTRARS------DKLHELEKENLQLKAKLHDMEM 396
Cdd:TIGR02169 258 EEISElEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEK-IGELEAEIASLERsiaekeRELEDAEERLAKLEAEIDKLLA 336
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 397 ERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTS-----ELSEAPQK--SLGHEVNELTSSRLLKLEmEN 469
Cdd:TIGR02169 337 EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdELKDYREKleKLKREINELKRELDRLQE-EL 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 470 QSLTKTVEELRTTVDSVEGnasKILKMEKENQRLSKKVEILEneivqekqslQNCQNLSKDLMKEKAQLEKTIETLREnS 549
Cdd:TIGR02169 416 QRLSEELADLNAAIAGIEA---KINELEEEKEDKALEIKKQE----------WKLEQLAADLSKYEQELYDLKEEYDR-V 481
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 550 ERQIKILEQENEHLNQTVSSLRQRsQISAEARVKDIEKENKILHESIKE---------------TSSKLSKIEFEKRQIK 614
Cdd:TIGR02169 482 EKELSKLQRELAEAEAQARASEER-VRGGRAVEEVLKASIQGVHGTVAQlgsvgeryataievaAGNRLNNVVVEDDAVA 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 615 KELEHY--KEKGERAEELE-NELHHLEKENELLQKK-----ITNLKITCEKIEA---------LEQENSELEREnrklkk 677
Cdd:TIGR02169 561 KEAIELlkRRKAGRATFLPlNKMRDERRDLSILSEDgvigfAVDLVEFDPKYEPafkyvfgdtLVVEDIEAARR------ 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 678 TLDSFKNLTFQLESLEKENS----------------QLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKkgl 741
Cdd:TIGR02169 635 LMGKYRMVTLEGELFEKSGAmtggsraprggilfsrSEPAELQRLRERLEGLK---RELSSLQSELRRIENRLDELS--- 708
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 742 ELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE--ELKISSKRLEQLEKENKS 819
Cdd:TIGR02169 709 QELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEelEEDLHKLEEALNDLEARL 788
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 820 LEQETSQLEKDKKQLEKENKRLRQQaeikdttLEENNVKIGNLEKENKTLSKEIgiyKESCVRLKELEKENKELVKRati 899
Cdd:TIGR02169 789 SHSRIPEIQAELSKLEEEVSRIEAR-------LREIEQKLNRLTLEKEYLEKEI---QELQEQRIDLKEQIKSIEKE--- 855
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 900 dIKTLVTLREDLVSEKLKTQQMNNDLEKlthelEKIGLNKERLLHDEQstddrYKLLESKLEsTLKKSLEIKEEKIAALE 979
Cdd:TIGR02169 856 -IENLNGKKEELEEELEELEAALRDLES-----RLGDLKKERDELEAQ-----LRELERKIE-ELEAQIEKKRKRLSELK 923
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 980 ARLEESTNYNQQLRQELKTVKKNYEAL-------KQRQDEERMVQSSPPIsgeDNKWERESQEttrellkVKDRLIEVER 1052
Cdd:TIGR02169 924 AKLEALEEELSEIEDPKGEDEEIPEEElsledvqAELQRVEEEIRALEPV---NMLAIQEYEE-------VLKRLDELKE 993
|
890 900
....*....|....*....|..
gi 208022632 1053 NNATLQAEKQALKTQLKQLETQ 1074
Cdd:TIGR02169 994 KRAKLEEERKAILERIEEYEKK 1015
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
626-1350 |
5.41e-16 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 83.92 E-value: 5.41e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 626 RAEELENELHHLEKENELLQKKITNL-KITCEKIEALEQENSELErenrKLKKTLDSFKNltfqleSLEKENSQLDEENL 704
Cdd:TIGR04523 34 EEKQLEKKLKTIKNELKNKEKELKNLdKNLNKDEEKINNSNNKIK----ILEQQIKDLND------KLKKNKDKINKLNS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 705 ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSyqgLDIENQRLQKTLENSNKKIQQLES 784
Cdd:TIGR04523 104 DLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEK---LNNKYNDLKKQKEELENELNLLEK 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK 864
Cdd:TIGR04523 181 EKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKD 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 865 ENKTLskeigiykescvrLKELEKENKELVKRATidiktlvtlredlvseklKTQQMNNDLEKLTHELEKigLNKERllh 944
Cdd:TIGR04523 261 EQNKI-------------KKQLSEKQKELEQNNK------------------KIKELEKQLNQLKSEISD--LNNQK--- 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 945 deqstddrykllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKnyealkqrqdeermvqssppisg 1024
Cdd:TIGR04523 305 ------------EQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKK----------------------- 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1025 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNA 1104
Cdd:TIGR04523 350 ELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1105 KLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLK 1184
Cdd:TIGR04523 430 RLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELE 509
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1185 SAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMlLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQ 1264
Cdd:TIGR04523 510 EKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKD-DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ 588
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1265 TDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQN 1344
Cdd:TIGR04523 589 ELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKI 668
|
....*.
gi 208022632 1345 MESKDL 1350
Cdd:TIGR04523 669 KESKTK 674
|
|
| HkD_Hook |
cd22222 |
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes ... |
15-163 |
8.72e-16 |
|
Hook domain found in Hook family of microtubule-binding proteins; The Hook family includes Hook1-3. Hook1 is a microtubule-binding protein required for spermatid differentiation. Hook2, also a microtubule-binding protein, contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. Hook adaptor proteins share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain, and contacts the helix alpha1 of dynein light intermediate chain 1 (LIC1) in a hydrophobic groove.
Pssm-ID: 411793 Cd Length: 147 Bit Score: 76.13 E-value: 8.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 15 TSPLVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKLESQ----RVNKKVNNDASLRMHNLSILVRQIKFYY 90
Cdd:cd22222 1 CDSLLQWLQTFN-LIAPHATAED----LSDGVAIAQVLNQIDPEYFSDswlsKIKPDVGDNWRLKVSNLKKILKGIVDYY 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 208022632 91 QETL-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22222 76 SEVLgQQISGFTMPDVNAIAEK----EDPKELGRLLQLVLGCAVNCERKEEYIQAIMGLEESVQHVVMEAIQEL 145
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
730-1320 |
1.88e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 82.42 E-value: 1.88e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 730 LESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKR 809
Cdd:PRK03918 160 YENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 810 LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqAEIKDttLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKE 889
Cdd:PRK03918 240 IEELEKELESLEGSKRKLEEKIRELEERIEELK--KEIEE--LEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 890 NKELVKRatidIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGlNKERLLHDEQSTDDRYKLLESKLEStlkKSLE 969
Cdd:PRK03918 316 LSRLEEE----INGIEERIKELEEKEERLEELKKKLKELEKRLEELE-ERHELYEEAKAKKEELERLKKRLTG---LTPE 387
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 970 IKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISG---EDNKWERESQETTRELLKVKDR 1046
Cdd:PRK03918 388 KLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGrelTEEHRKELLEEYTAELKRIEKE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1047 LIEVErnnatlqAEKQALKTQLKQLETqnnnlqaqILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ 1126
Cdd:PRK03918 468 LKEIE-------EKERKLRKELRELEK--------VLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKE 532
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1127 LLIQqssLENENESVIKEREDLKSLYDSLIKDHEKLELLhERQASEYESLISKHGTlkSAHKNLEVEHRDLE---DRYNQ 1203
Cdd:PRK03918 533 KLIK---LKGEIKSLKKELEKLEELKKKLAELEKKLDEL-EEELAELLKELEELGF--ESVEELEERLKELEpfyNEYLE 606
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1204 LLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSqllketevlQTDHKNLKSLLNNSKLEQTR 1283
Cdd:PRK03918 607 LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYS---------EEEYEELREEYLELSRELAG 677
|
570 580 590
....*....|....*....|....*....|....*..
gi 208022632 1284 LEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLE 1320
Cdd:PRK03918 678 LRAELEELEKRREEIKKTLEKLKEELEEREKAKKELE 714
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
309-1107 |
3.39e-15 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 82.04 E-value: 3.39e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 309 RDELDALREKAVRVDKLESEVSRYKERLH----DIEFYKARVEELKEDNQ-VLLETKTMLEDQLEGTRARsdkLHELEKE 383
Cdd:TIGR02169 176 LEELEEVEENIERLDLIIDEKRQQLERLRrereKAERYQALLKEKREYEGyELLKEKEALERQKEAIERQ---LASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTL---EMAQKQSMDESLHLgwELEQISRTSELSEAPQKSLghevneltSS 460
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeeEQLRVKEKIGELEA--EIASLERSIAEKERELEDA--------EE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 461 RLLKLEMENQSLTKTVEELRTtvdSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK 540
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELER---EIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKR 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 541 TIETLRENSERQI---KILEQENEHLNQTVSSLRQRsQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK--- 614
Cdd:TIGR02169 400 EINELKRELDRLQeelQRLSEELADLNAAIAGIEAK-INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKeey 478
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 615 ----KELehykekgeraEELENELHHLEKENELLQKKITNLKITCEKIEALEQ----ENSELERENRKLKKTLDS----- 681
Cdd:TIGR02169 479 drveKEL----------SKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgTVAQLGSVGERYATAIEVaagnr 548
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 682 FKNLTFQLESLEKENSQ-LDEENL---------ELRRNVESLKCASMKMAQLQLEN-KELESEKEQLKK---GLELLKAS 747
Cdd:TIGR02169 549 LNNVVVEDDAVAKEAIElLKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDlVEFDPKYEPAFKyvfGDTLVVED 628
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 748 FKKTERLEVSYQGLDIENQRLQKT-----------LENSNK-----KIQQLESELQDLEMENQTLQKNLEELKissKRLE 811
Cdd:TIGR02169 629 IEAARRLMGKYRMVTLEGELFEKSgamtggsraprGGILFSrsepaELQRLRERLEGLKRELSSLQSELRRIE---NRLD 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Cdd:TIGR02169 706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLE 785
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 892 ELVKRATIDIKT--LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEStLKKSLE 969
Cdd:TIGR02169 786 ARLSHSRIPEIQaeLSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEN-LNGKKE 864
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 970 IKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEermvqssppISGEDNKWERESQETTRELLKVKDRLIE 1049
Cdd:TIGR02169 865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE---------LEAQIEKKRKRLSELKAKLEALEEELSE 935
|
810 820 830 840 850 860 870
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 208022632 1050 VERNNA-------------TLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQ 1107
Cdd:TIGR02169 936 IEDPKGedeeipeeelsleDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
556-1317 |
7.63e-15 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 80.55 E-value: 7.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 556 LEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETSSKLSKIEFEKRQIkkeLEHYKEKGERAEELENELH 635
Cdd:pfam15921 76 IERVLEEYSHQVKDLQRRLNESNELH----EKQKFYLRQSVIDLQTKLQEMQMERDAM---ADIRRRESQSQEDLRNQLQ 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 636 HLEKENELLQkkitnlkitCEKIEALEQENSELErenrKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKC 715
Cdd:pfam15921 149 NTVHELEAAK---------CLKEDMLEDSNTQIE----QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHF 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 716 ASMKMAQLQLEnKELESEKEQLK-------KGLELLKA-SFKKTERLEVSYQgldienQRLQKTLENSNKKIQQLESELQ 787
Cdd:pfam15921 216 RSLGSAISKIL-RELDTEISYLKgrifpveDQLEALKSeSQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKAS 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 788 DLEMENQTLQKNLEELKISSKR-----LEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL 862
Cdd:pfam15921 289 SARSQANSIQSQLEIIQEQARNqnsmyMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQF 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 863 EKENKTLSKEI-GIYKESCVRLKEL--EKE-NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLN 938
Cdd:pfam15921 369 SQESGNLDDQLqKLLADLHKREKELslEKEqNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMER 448
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 939 KERLLHDEQSTDDRYKLLESKLEST---LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVK-KNYEALKQRQDEER 1014
Cdd:pfam15921 449 QMAAIQGKNESLEKVSSLTAQLESTkemLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEaTNAEITKLRSRVDL 528
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1015 MVQSSPPISGEDNKWERESQETTRELLKV--KDRLIEVERNNATLQAE--------KQALKTQLKQLETQNNNLQaqiLA 1084
Cdd:pfam15921 529 KLQELQHLKNEGDHLRNVQTECEALKLQMaeKDKVIEILRQQIENMTQlvgqhgrtAGAMQVEKAQLEKEINDRR---LE 605
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1085 LQRQTVSLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLEL 1164
Cdd:pfam15921 606 LQEFKILKDKKDAKIRELEARV----SDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKR 681
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1165 LHERQASEYESLISK-HGTLKSAHKNLEVEHRDLEDR--------------YNQLLKQKGQLEDLEKMLKVEQEKMLLEN 1229
Cdd:pfam15921 682 NFRNKSEEMETTTNKlKMQLKSAQSELEQTRNTLKSMegsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEAMTNAN 761
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1230 KNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQC 1309
Cdd:pfam15921 762 KEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQH 841
|
....*....
gi 208022632 1310 EL-LSQLKG 1317
Cdd:pfam15921 842 TLdVKELQG 850
|
|
| HOOK_N |
pfam19047 |
HOOK domain; This domain is found at the N-terminus of HOOK proteins. |
18-163 |
1.40e-14 |
|
HOOK domain; This domain is found at the N-terminus of HOOK proteins.
Pssm-ID: 465958 Cd Length: 151 Bit Score: 72.83 E-value: 1.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 18 LVTWVKTFGpLAAGNGTNLDeyvaLVDGVFLNQVMLQINPKLES----QRVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:pfam19047 6 LLTWLQTFN-VPAPCATVED----LTDGVAMAQVLHQIDPSWFTeawlSRIKEDVGDNWRLKVSNLKKILQSVVDYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 208022632 94 L-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:pfam19047 81 LgQQISDFLLPDVNLIGEH----SDPAELGRLLQLILGCAVNCEKKQEYIQQIMTLEESVQHVVMTAIQEL 147
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
252-943 |
1.42e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 79.60 E-value: 1.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 252 ELADAKAKIRRLRQELEEKTEQLldckqeleqmeielKRLQQEnmnllsdARSARMYRdeldALREKAVRVDkLESEVSR 331
Cdd:COG1196 180 KLEATEENLERLEDILGELERQL--------------EPLERQ-------AEKAERYR----ELKEELKELE-AELLLLK 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 332 YKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRArsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRL---ELEELELELEEAQAEEYELLAELARLEQDIARLEER 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 412 NMTLEMAQKQsmdeslhLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgnas 491
Cdd:COG1196 311 RRELEERLEE-------LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEE---- 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 492 KILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Cdd:COG1196 380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 572 QRSQISAEARVKDIEKENKILHESIKEtSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Cdd:COG1196 460 ALLELLAELLEEAALLEAALAELLEEL-AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEA 538
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 652 KITCEKIEALEQENSELERENRKLKKTLDSFKN--LTFQLESLEKENSQLDEENLELRRN------VESLKCASMKMAQL 723
Cdd:COG1196 539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAgrATFLPLDKIRARAALAAALARGAIGaavdlvASDLREADARYYVL 618
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 724 QLENKELESEKEQLKKGLELLKASfkkTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Cdd:COG1196 619 GDTLLGRTLVAARLEAALRRAVTL---AGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELEL 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEN----KTLSKEIGIYKEs 879
Cdd:COG1196 696 EEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEppdlEELERELERLER- 774
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 208022632 880 cvRLKELEK-------ENKELVKRATidikTLVTLREDLVSEKlktqqmnNDLEKLTHELEKIGlnKERLL 943
Cdd:COG1196 775 --EIEALGPvnllaieEYEELEERYD----FLSEQREDLEEAR-------ETLEEAIEEIDRET--RERFL 830
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
313-828 |
1.71e-14 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 79.31 E-value: 1.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 313 DALREKAVRVDKLESEVSRYKER-LHD--------IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKE 383
Cdd:PRK02224 180 RVLSDQRGSLDQLKAQIEEKEEKdLHErlngleseLAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAE 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDEslhlgweleqisrtSELSEAPQKSLghevneltSSRLL 463
Cdd:PRK02224 260 IEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAE--------------AGLDDADAEAV--------EARRE 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 464 KLEMENQSLTKTVEELRTTV----DSVEGNASKILKMEKENQRLSKKVEILENEivqekqsLQNCQNLSKDLMKEKAQLE 539
Cdd:PRK02224 318 ELEDRDEELRDRLEECRVAAqahnEEAESLREDADDLEERAEELREEAAELESE-------LEEAREAVEDRREEIEELE 390
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 540 KTIETLRE---NSERQIKILEQENEHLNQTVSSLRQRSQiSAEARVKDIEK---ENKILHE------------------S 595
Cdd:PRK02224 391 EEIEELRErfgDAPVDLGNAEDFLEELREERDELREREA-ELEATLRTARErveEAEALLEagkcpecgqpvegsphveT 469
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 596 IKETSSKLSKIEFEKRQIKKELEHYKEKGERAEEL---ENELHHLEKENELLQKKITNLKITC----EKIEALEQENSEL 668
Cdd:PRK02224 470 IEEDRERVEELEAELEDLEEEVEEVEERLERAEDLveaEDRIERLEERREDLEELIAERRETIeekrERAEELRERAAEL 549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 669 ERENR----KLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL 744
Cdd:PRK02224 550 EAEAEekreAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERL 629
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 745 KASFKKTERLEVSYQGLDIENQRLQKtlENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQET 824
Cdd:PRK02224 630 AEKRERKRELEAEFDEARIEEAREDK--ERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRV 707
|
....
gi 208022632 825 SQLE 828
Cdd:PRK02224 708 EALE 711
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
616-1382 |
4.08e-14 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 78.47 E-value: 4.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 616 ELEHYKEKGERAEELEnelhhlEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Cdd:pfam02463 164 GSRLKRKKKEALKKLI------EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 696 NSQLDEENLELRRNVESLKCASMKMAQ--LQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLE 773
Cdd:pfam02463 238 RIDLLQELLRDEQEEIESSKQEIEKEEekLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLK 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 774 NSNKKIQQLESELQDLEMENQTLQKNLEELKIS-SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:pfam02463 318 ESEKEKKKAEKELKKEKEEIEELEKELKELEIKrEAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEEL 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 853 EENNVKIGNLEKENKTLSKEIGIYKEscvRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHEL 932
Cdd:pfam02463 398 ELKSEEEKEAQLLLELARQLEDLLKE---EKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 933 EKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:pfam02463 475 KETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVS 554
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1013 ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL 1092
Cdd:pfam02463 555 ATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTEL 634
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1093 QEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHE-RQAS 1171
Cdd:pfam02463 635 TKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKeELKK 714
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1172 EYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNH 1251
Cdd:pfam02463 715 LKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1252 TYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLnnqcELLSQLKGNLEEENRHLLDQIQ 1331
Cdd:pfam02463 795 KLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKL----EKLAEEELERLEEEITKEELLQ 870
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|.
gi 208022632 1332 TLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKF 1382
Cdd:pfam02463 871 ELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEE 921
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
477-829 |
2.33e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 75.86 E-value: 2.33e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 477 EELRTTVDSVEgnaSKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQIKIL 556
Cdd:TIGR02168 680 EELEEKIEELE---EKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL----EERIAQL 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKiLHESIKETSSKLSKIEFEKRQIKKEL----EHYKEKGERAEELEN 632
Cdd:TIGR02168 753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEE-LEAQIEQLKEELKALREALDELRAELtllnEEAANLRERLESLER 831
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 633 ELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNL----TFQLESLEKENSQLDEENLELRR 708
Cdd:TIGR02168 832 RIAATERRLEDLEEQIEELS---EDIESLAAEIEELEELIEELESELEALLNEraslEEALALLRSELEELSEELRELES 908
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 709 NVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFkkTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQD 788
Cdd:TIGR02168 909 KRSELR---RELEELREKLAQLELRLEGLEVRIDNLQERL--SEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 208022632 789 LEMENQTlqkNLEELKISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:TIGR02168 984 LGPVNLA---AIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
339-1306 |
2.42e-13 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 75.95 E-value: 2.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 339 IEFYKA----RVEELKE--DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEEN 412
Cdd:PTZ00121 1018 IDFNQNfnieKIEELTEygNNDDVLKEKDIIDEDIDGNHEGKAEAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAF 1097
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 413 MTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKlEMENQSLTKTVEELRTTVDSVEGNASK 492
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE-DAKRVEIARKAEDARKAEEARKAEDAK 1176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 493 ILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ---ENEHLNQTVSS 569
Cdd:PTZ00121 1177 KAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAkkaEEERNNEEIRK 1256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 570 LRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGE---RAEELENELHHLEKENELLQK 646
Cdd:PTZ00121 1257 FEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEeakKADEAKKKAEEAKKKADAAKK 1336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 647 KITNLKITCE------KIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS-QLDEENLELRRNVESLKcasmK 719
Cdd:PTZ00121 1337 KAEEAKKAAEaakaeaEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdEAKKKAEEDKKKADELK----K 1412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 720 MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQtLQKN 799
Cdd:PTZ00121 1413 AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADE-AKKK 1491
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 800 LEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTtleENNVKIGNLEKENKTLSKEigiyKES 879
Cdd:PTZ00121 1492 AEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKA---EEKKKADELKKAEELKKAE----EKK 1564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 880 CVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIglnKERLLHDEQSTDDRYKLLESK 959
Cdd:PTZ00121 1565 KAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKI---KAEELKKAEEEKKKVEQLKKK 1641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 960 LESTLKKSLEIKEE------KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQssppisgEDNKWERES 1033
Cdd:PTZ00121 1642 EAEEKKKAEELKKAeeenkiKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE-------ELKKKEAEE 1714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1034 QETTRELLKVKD-RLIEVERNNATLQAEKQALKtQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENST 1112
Cdd:PTZ00121 1715 KKKAEELKKAEEeNKIKAEEAKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRR 1793
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1113 LNSQSTSLMNQNAQLLIQQSSleNENESVIKereDLKSLYDSLIKdheklellherqaseyESLISKHGTLKSAHKnlev 1192
Cdd:PTZ00121 1794 MEVDKKIKDIFDNFANIIEGG--KEGNLVIN---DSKEMEDSAIK----------------EVADSKNMQLEEADA---- 1848
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1193 ehrdledrynqllkqkgqledlekmlkVEQEKMLLENKNHETVAAEykklcgendrlnhtySQLLKETEVLQTDHKNLKS 1272
Cdd:PTZ00121 1849 ---------------------------FEKHKFNKNNENGEDGNKE---------------ADFNKEKDLKEDDEEEIEE 1886
|
970 980 990
....*....|....*....|....*....|....
gi 208022632 1273 LLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLN 1306
Cdd:PTZ00121 1887 ADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLD 1920
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
256-1096 |
4.80e-13 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 74.70 E-value: 4.80e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 256 AKAKIRRLRQELEEKTEQLLDCKQELEQMEIEL----KRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSR 331
Cdd:TIGR00606 187 ALETLRQVRQTQGQKVQEHQMELKYLKQYKEKAceirDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMK 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 332 YKERLHDIEFYKARVEELKED-NQVLLETKTMLEDQL-EGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELM 409
Cdd:TIGR00606 267 LDNEIKALKSRKKQMEKDNSElELKMEKVFQGTDEQLnDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 410 EENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGH-EVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEG 488
Cdd:TIGR00606 347 VEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSErQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQE 426
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 489 NASKI-LKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL---SKDLMKEKAQLEKTIETL---RENS------------ 549
Cdd:TIGR00606 427 QADEIrDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLegsSDRILELDQELRKAERELskaEKNSltetlkkevksl 506
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 550 -------ERQIKILEQENEHLNQTVSSLRQ-----RSQISAEARVKDIEKENKILHESI-------KETSSKLSKIEFEK 610
Cdd:TIGR00606 507 qnekadlDRKLRKLDQEMEQLNHHTTTRTQmemltKDKMDKDEQIRKIKSRHSDELTSLlgyfpnkKQLEDWLHSKSKEI 586
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 611 RQIKKELEHYKEKGERAEELEnelHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQ-- 688
Cdd:TIGR00606 587 NQTRDRLAKLNKELASLEQNK---NHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRAMLAGAta 663
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 689 -----LESLEKENS----------QLDEENLELRRNVES-LKCASMKMAQLQLENKELESEKEQLKKGLE----LLKASF 748
Cdd:TIGR00606 664 vysqfITQLTDENQsccpvcqrvfQTEAELQEFISDLQSkLRLAPDKLKSTESELKKKEKRRDEMLGLAPgrqsIIDLKE 743
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ---DLEMENQTLQKNLEELKISSKRLEQLEKENKS--LEQE 823
Cdd:TIGR00606 744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEEsakVCLTDVTIMERFQMELKDVERKIAQQAAKLQGsdLDRT 823
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Cdd:TIGR00606 824 VQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIRE 903
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 904 LVTLRED---LVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRY-KLLESKLESTLKKSLEIKEEKIAALE 979
Cdd:TIGR00606 904 IKDAKEQdspLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYmKDIENKIQDGKDDYLKQKETELNTVN 983
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 980 ARLEESTNYNQQLRQELKTVKKNYEALKQRqdeERMVQSSPPISGEDNKWeRESQETTRELLKV--KDRLIEVERNNATL 1057
Cdd:TIGR00606 984 AQLEECEKHQEKINEDMRLMRQDIDTQKIQ---ERWLQDNLTLRKRENEL-KEVEEELKQHLKEmgQMQVLQMKQEHQKL 1059
|
890 900 910
....*....|....*....|....*....|....*....
gi 208022632 1058 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQN 1096
Cdd:TIGR00606 1060 EENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRD 1098
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
882-1387 |
7.11e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.20 E-value: 7.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLE 961
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 962 StLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERESQETTRELL 1041
Cdd:COG1196 320 E-LEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE--AEEELEELAEELLEALRAAA 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1042 KVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLM 1121
Cdd:COG1196 397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1122 NQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQA--------SEYESLISKHGTLKSAHKNLEVE 1193
Cdd:COG1196 477 AALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavligveAAYEAALEAALAAALQNIVVEDD 556
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1194 hRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSL 1273
Cdd:COG1196 557 -EVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1274 LNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHV 1353
Cdd:COG1196 636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715
|
490 500 510
....*....|....*....|....*....|....
gi 208022632 1354 EQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSP 1387
Cdd:COG1196 716 RLEEELEEEALEEQLEAEREELLEELLEEEELLE 749
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
257-836 |
1.32e-12 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 73.13 E-value: 1.32e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 257 KAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDEL-DALREKAVRVDKLESEVSRYKER 335
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLeKEKLNIQKNIDKIKNKLLKLELL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 336 LHDIEFY-------KARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDMEMERDMDRKK 404
Cdd:TIGR04523 203 LSNLKKKiqknkslESQISELKKQNNQLKDNIEKKQQEINEKTTEisntQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 405 IEELMEENMTLEMA-----QKQSMDESLHLGWELEQISRT-----SELSEAPQK--SLGHEVNELTSSrLLKLEMENQSL 472
Cdd:TIGR04523 283 IKELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKleeiqNQISQNNKIisQLNEQISQLKKE-LTNSESENSEK 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 473 TKTVEElrttvdsvegNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLrensERQ 552
Cdd:TIGR04523 362 QRELEE----------KQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELL----EKE 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 553 IKILEQENEHLNQTVSSLRqrSQISA-EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELehyKEKGERAEELE 631
Cdd:TIGR04523 428 IERLKETIIKNNSEIKDLT--NQDSVkELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKEL---KSKEKELKKLN 502
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 632 NELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSfKNLTFQLESLEKENSQLDEENLELRRNVE 711
Cdd:TIGR04523 503 EEKKELEEKVKDLTKKISSLK---EKIEKLESEKKEKESKISDLEDELNK-DDFELKKENLEKEIDEKNKEIEELKQTQK 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 712 SLKcasMKMAQLQLENKELESEKEQLKKGLEL-----------LKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 780
Cdd:TIGR04523 579 SLK---KKQEEKQELIDQKEKEKKDLIKEIEEkekkisslekeLEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIK 655
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 208022632 781 QLESELQDLEMENQTLQKNLEEL---------------------KISSKRLEQLEKENKSLEQETSQLEKDKKQLEK 836
Cdd:TIGR04523 656 EIRNKWPEIIKKIKESKTKIDDIielmkdwlkelslhykkyitrMIRIKDLPKLEEKYKEIEKELKKLDEFSKELEN 732
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
705-1379 |
2.40e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 72.40 E-value: 2.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 705 ELRRNVESLKcasmKMAQLQLENKELESEKEQLKKGLELLKAsfkkterlevsyqgldienQRLQKTLENSNKKIQQLES 784
Cdd:TIGR02168 197 ELERQLKSLE----RQAEKAERYKELKAELRELELALLVLRL-------------------EELREELEELQEELKEAEE 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 785 ELQDLEMENQTLQKNLEELkisskRLEQLEkenksleqetsqLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK 864
Cdd:TIGR02168 254 ELEELTAELQELEEKLEEL-----RLEVSE------------LEEEIEELQKELYALANEISRLEQQKQILRERLANLER 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 865 ENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKtlvTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLH 944
Cdd:TIGR02168 317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELE---SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 945 DEQSTDDRYKLLESKLEStLKKSLEIKEEKIAALEARLEEstnyNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISG 1024
Cdd:TIGR02168 394 QIASLNNEIERLEARLER-LEDRRERLQQEIEELLKKLEE----AELKELQAELEELEEELEELQEELERLEEALEELRE 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1025 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKqletqNNNLQAQILALQRQTVSLQEQ-----NTTL 1099
Cdd:TIGR02168 469 ELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK-----NQSGLSGILGVLSELISVDEGyeaaiEAAL 543
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1100 QTQNAKLQVENSTLNSQSTSLMNQNAQL--------LIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHE---- 1167
Cdd:TIGR02168 544 GGRLQAVVVENLNAAKKAIAFLKQNELGrvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSyllg 623
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1168 ------------RQASEY---ESLISKHGTLKSAH---------------------KNLEVEHRDLEDRYNQLLKQ---- 1207
Cdd:TIGR02168 624 gvlvvddldnalELAKKLrpgYRIVTLDGDLVRPGgvitggsaktnssilerrreiEELEEKIEELEEKIAELEKAlael 703
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1208 KGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAE 1287
Cdd:TIGR02168 704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1288 FSKLKEQYQQLditSTKLNNQCELLSQLKGNLEEENRHLLDQIQTL--MLQNRTLLEQNMESKDLFHVEQRQYIDKLNEL 1365
Cdd:TIGR02168 784 IEELEAQIEQL---KEELKALREALDELRAELTLLNEEAANLRERLesLERRIAATERRLEDLEEQIEELSEDIESLAAE 860
|
730
....*....|....
gi 208022632 1366 RRQKEKLEEKIMDQ 1379
Cdd:TIGR02168 861 IEELEELIEELESE 874
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
340-1176 |
2.96e-12 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 72.31 E-value: 2.96e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 340 EFYKARVEELKEDNQVL--LETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK--IEELMEENMTL 415
Cdd:pfam02463 166 RLKRKKKEALKKLIEETenLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLklNEERIDLLQEL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 416 EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILK 495
Cdd:pfam02463 246 LRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKK 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 496 MEKENQRLSKKVEILENEI-VQEKQSLQN---CQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLR 571
Cdd:pfam02463 326 AEKELKKEKEEIEELEKELkELEIKREAEeeeEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEK 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 572 QRSQISAEARVKDIEKENKILhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNL 651
Cdd:pfam02463 406 EAQLLLELARQLEDLLKEEKK-EELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN---LELRRNVESLKCASMKMAQLQLENK 728
Cdd:pfam02463 485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVaveNYKVAISTAVIVEVSATADEVEERQ 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 729 ELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQR-LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS 807
Cdd:pfam02463 565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILnLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELE 887
Cdd:pfam02463 645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLA 724
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 888 KENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE-KLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKK 966
Cdd:pfam02463 725 DRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEeEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 967 SLEIKEEKIAALEARLEESTNyNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTREllkVKDR 1046
Cdd:pfam02463 805 ALEEELKEEAELLEEEQLLIE-QEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKE---EELE 880
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1047 LIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTS----LMN 1122
Cdd:pfam02463 881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENnkeeEEE 960
|
810 820 830 840 850
....*....|....*....|....*....|....*....|....*....|....
gi 208022632 1123 QNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESL 1176
Cdd:pfam02463 961 RNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEE 1014
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
369-751 |
4.84e-12 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 71.63 E-value: 4.84e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 369 GTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQK 448
Cdd:TIGR02168 671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 449 SLGHEVNELTSSRLLKLEM--ENQSLTKTVEELRTTVDsvegnaSKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN 526
Cdd:TIGR02168 751 QLSKELTELEAEIEELEERleEAEEELAEAEAEIEELE------AQIEQLKEELKALREALDELRAELTLLNEEAANLRE 824
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 527 LSKDLMKEKAQLEKTIETLRENSER---QIKILEQENEHLNQTVSSLRQRSQI------SAEARVKDIEKENKILHESIK 597
Cdd:TIGR02168 825 RLESLERRIAATERRLEDLEEQIEElseDIESLAAEIEELEELIEELESELEAllneraSLEEALALLRSELEELSEELR 904
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 598 ETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELhhLEKENELLQkkiTNLKITCEKIEALEQENSELERENRKLKK 677
Cdd:TIGR02168 905 ELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL--QERLSEEYS---LTLEEAEALENKIEDDEEEARRRLKRLEN 979
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 208022632 678 TLDSFKNLTF----QLESLEKENSQLDEENLELRRNVESLKCASMKMaqlqleNKELeseKEQLKKGLELLKASFKKT 751
Cdd:TIGR02168 980 KIKELGPVNLaaieEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI------DREA---RERFKDTFDQVNENFQRV 1048
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
244-713 |
6.33e-12 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 70.84 E-value: 6.33e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 244 ESRQHLSV---ELADAKAKIRR-------LRQELEEKTEQLLDCKQELEQM--EIELKRLQQENMNLLSDARSARmyRDE 311
Cdd:PRK02224 248 ERREELETleaEIEDLRETIAEterereeLAEEVRDLRERLEELEEERDDLlaEAGLDDADAEAVEARREELEDR--DEE 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 312 L-DALREKAVRVDKLESEVSRYKERLHDIEfykARVEELKEDNQVLletKTMLEDQLEGTRARSDKLHELEKENLQLKAK 390
Cdd:PRK02224 326 LrDRLEECRVAAQAHNEEAESLREDADDLE---ERAEELREEAAEL---ESELEEAREAVEDRREEIEELEEEIEELRER 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 391 LHDMEMER-------DMDRKKIEELMEENMTLEmAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL 463
Cdd:PRK02224 400 FGDAPVDLgnaedflEELREERDELREREAELE-ATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVE 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 464 KLEMENQSLTKTVEELRTTVDSVEgnasKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Cdd:PRK02224 479 ELEAELEDLEEEVEEVEERLERAE----DLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAE 554
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 544 TLRENSERQikilEQENEHLNQTVSSLRQRSQISAEArvkdIEKENKI--LHESIKETSSKLSKIEfEKRQIKKEL---- 617
Cdd:PRK02224 555 EKREAAAEA----EEEAEEAREEVAELNSKLAELKER----IESLERIrtLLAAIADAEDEIERLR-EKREALAELnder 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 618 -EHYKEKGERAEELENELH--HLEKENELLQKKITNLKITCEKIEALEQENSELE----------RENRKLKKTLDSFKN 684
Cdd:PRK02224 626 rERLAEKRERKRELEAEFDeaRIEEAREDKERAEEYLEQVEEKLDELREERDDLQaeigavenelEELEELRERREALEN 705
|
490 500 510
....*....|....*....|....*....|....
gi 208022632 685 LTFQLESLEKENSQLDEENLELR-----RNVESL 713
Cdd:PRK02224 706 RVEALEALYDEAEELESMYGDLRaelrqRNVETL 739
|
|
| HkD_Hook2 |
cd22227 |
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a ... |
18-163 |
1.58e-11 |
|
Hook domain found in protein Hook 2 (Hook2) and similar proteins; Hook2 is a microtubule-binding protein that contributes to the establishment and maintenance of centrosome function. It may function in the positioning or formation of aggresomes, which are pericentriolar accumulations of misfolded proteins, proteasomes and chaperones. Hook2 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411798 Cd Length: 150 Bit Score: 64.13 E-value: 1.58e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 18 LVTWVKTFGPLAAGNgtnldEYVALVDGVFLNQVMLQINPKLES----QRVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:cd22227 6 LLTWLQTFQVPSPCS-----SYQDLTSGVAIAQVLNRIDPSWFNeawlGRIKEDTGDNWRLKVSNLKKILQSLLEYYQDV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 208022632 94 L-QQLIMMSLPNVLIIGKnpFSEqgTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22227 81 LgHQVSEDHLPDVNLIGE--FSD--DTELGKLLQLVLGCAISCEKKQEHIQQIMTLEESVQHVVMEAIQEL 147
|
|
| HkD_Hook3 |
cd22226 |
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein ... |
18-163 |
1.77e-11 |
|
Hook domain found in protein Hook 3 (Hook3) and similar proteins; Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking. It is involved in Golgi and endosome transport. It acts as a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and the kinesin KIF1C. It may participate in the turnover of the endocytosed scavenger receptor. Hook3 is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411797 Cd Length: 153 Bit Score: 64.22 E-value: 1.77e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 18 LVTWVKTFGPLAAGngTNLDEyvaLVDGVFLNQVMLQINPKLESQ----RVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:cd22226 9 LLTWIQTFNVDAPC--QTVED---LTSGVVMAQVLQKIDPAYFDEnwlnRIKTEVGDNWRLKISNLKKILKGILDYNHEI 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 208022632 94 L-QQLIMMSLPNVLIIGKNpfseQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22226 84 LgQQINDFTLPDVNLIGEH----SDAAELGRMLQLILGCAVNCEQKQEYIQTIMMMEESVQHVVMTAIQEL 150
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
257-1376 |
2.60e-11 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 69.31 E-value: 2.60e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 257 KAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNL----LSDARSARMYRDELDALReKAVRVDKLESEVSRY 332
Cdd:TIGR01612 557 KKLIHEIKKELEEENEDSIHLEKEIKDLFDKYLEIDDEIIYInklkLELKEKIKNISDKNEYIK-KAIDLKKIIENNNAY 635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 333 KERLHDIEFYKArVEELKEDNQVLLETKTMLEDQLEGTRAR-----SDKLHELEKENLQLKAKLHDMEMERDMDRKKIEE 407
Cdd:TIGR01612 636 IDELAKISPYQV-PEHLKNKDKIYSTIKSELSKIYEDDIDAlynelSSIVKENAIDNTEDKAKLDDLKSKIDKEYDKIQN 714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 408 LMEENMTLEMAQKQSMDESL---------HLGWEL-EQISRTSELSEAPQKSLGHEVNELTSSR-----------LLKLE 466
Cdd:TIGR01612 715 METATVELHLSNIENKKNELldiiveikkHIHGEInKDLNKILEDFKNKEKELSNKINDYAKEKdelnkykskisEIKNH 794
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 467 MENQSLTKTV--EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKD-LMKEKAQLEKTIE 543
Cdd:TIGR01612 795 YNDQINIDNIkdEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFINFENNCKEkIDSEHEQFAELTN 874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 544 TLR-ENSERQIKILEQE----NEHLNQTVSSLRQRSQ-ISAEARVKDIEKENKILHESIKETSSKLSKIefeKRQIKKEL 617
Cdd:TIGR01612 875 KIKaEISDDKLNDYEKKfndsKSLINEINKSIEEEYQnINTLKKVDEYIKICENTKESIEKFHNKQNIL---KEILNKNI 951
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 618 EHYKEKGERAEELENELhhlekENELLQKKITNLKITCE-KIEALEQENSELERENRKLKKTLDSFKN--LTFQLESLEK 694
Cdd:TIGR01612 952 DTIKESNLIEKSYKDKF-----DNTLIDKINELDKAFKDaSLNDYEAKNNELIKYFNDLKANLGKNKEnmLYHQFDEKEK 1026
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 695 ENSQLDEENLELRRNVESLKCA---SMKMAQLQLEN---KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRL 768
Cdd:TIGR01612 1027 ATNDIEQKIEDANKNIPNIEIAihtSIYNIIDEIEKeigKNIELLNKEILEEAEINITNFNEIKEKLKHYNFDDFGKEEN 1106
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 769 QKTLENSNKKiqqleseLQDLEMENQTLQKNLEELKISSKRLEQLEKENKSleqETSQLEK---------DKKQLEKENK 839
Cdd:TIGR01612 1107 IKYADEINKI-------KDDIKNLDQKIDHHIKALEEIKKKSENYIDEIKA---QINDLEDvadkaisndDPEEIEKKIE 1176
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 840 RLRQQAEIKDTTLEENN---VKIGNLEKENKTLSKEIGI---YKESCVRLKeLEKENKElVKRATIDIKTLVTLREDLVS 913
Cdd:TIGR01612 1177 NIVTKIDKKKNIYDEIKkllNEIAEIEKDKTSLEEVKGInlsYGKNLGKLF-LEKIDEE-KKKSEHMIKAMEAYIEDLDE 1254
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 914 EKLKTQQMNNDL---EKLTHELEKIGLNKERLL--------HDEQSTDDRYKLLESKLESTLKKSL-EIKEEkiaaLEAR 981
Cdd:TIGR01612 1255 IKEKSPEIENEMgieMDIKAEMETFNISHDDDKdhhiiskkHDENISDIREKSLKIIEDFSEESDInDIKKE----LQKN 1330
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 982 LEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQssppISGEDNKWERESQETTRELLKvKDRLIEVERNNATLQAEK 1061
Cdd:TIGR01612 1331 LLDAQKHNSDINLYLNEIANIYNILKLNKIKKIIDE----VKEYTKEIEENNKNIKDELDK-SEKLIKKIKDDINLEECK 1405
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1062 QALKTqlkQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQ--LLIQQSSLENE-- 1137
Cdd:TIGR01612 1406 SKIES---TLDDKDIDECIKKIKELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQhiLKIKKDNATNDhd 1482
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1138 -NESVIKERED----LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLK------SAHKNLEVEHRDLEDRYNQLLK 1206
Cdd:TIGR01612 1483 fNINELKEHIDkskgCKDEADKNAKAIEKNKELFEQYKKDVTELLNKYSALAiknkfaKTKKDSEIIIKEIKDAHKKFIL 1562
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1207 QKGQLEdlEKMLKVEQEKMLLENKnhetvaaeykklCGENDRLNHTYSQLLKETEVLQTDH---KNLKSLLNNSKLEQTR 1283
Cdd:TIGR01612 1563 EAEKSE--QKIKEIKKEKFRIEDD------------AAKNDKSNKAAIDIQLSLENFENKFlkiSDIKKKINDCLKETES 1628
|
1130 1140 1150 1160 1170 1180 1190 1200
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1284 LEAEFSKLK--EQYQQLDITSTKLNNQCELLSQLKG---NLEEENRHlLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQY 1358
Cdd:TIGR01612 1629 IEKKISSFSidSQDTELKENGDNLNSLQEFLESLKDqkkNIEDKKKE-LDELDSEIEKIEIDVDQHKKNYEIGIIEKIKE 1707
|
1210 1220
....*....|....*....|
gi 208022632 1359 IDKLN--ELRRQKEKLEEKI 1376
Cdd:TIGR01612 1708 IAIANkeEIESIKELIEPTI 1727
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
182-801 |
2.95e-11 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 68.99 E-value: 2.95e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 182 SQEDIEPLLKNMALHLKRLIDErdeHSETIIELSEERDGlhflphASSSAQSPCGSPGMKRTESRQHLSV---ELADAKA 258
Cdd:pfam15921 254 SQNKIELLLQQHQDRIEQLISE---HEVEITGLTEKASS------ARSQANSIQSQLEIIQEQARNQNSMymrQLSDLES 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 259 KIRRLRQELEEKTEQLLDCKQELEqmeielKRLQQENmnllSDARSARMYRDEL--------DALREKAVRVDKLESEVS 330
Cdd:pfam15921 325 TVSQLRSELREAKRMYEDKIEELE------KQLVLAN----SELTEARTERDQFsqesgnldDQLQKLLADLHKREKELS 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 331 RYKE---RLHD--------IEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKL-HDMEMER 398
Cdd:pfam15921 395 LEKEqnkRLWDrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLtAQLESTK 474
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 399 DMDRKKIEELMEENMTLEMAQKQSMDeslhLGWELEQISRTSELSEApqkslghEVNELTSSRLLKLEmENQSLTKTVEE 478
Cdd:pfam15921 475 EMLRKVVEELTAKKMTLESSERTVSD----LTASLQEKERAIEATNA-------EITKLRSRVDLKLQ-ELQHLKNEGDH 542
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 479 LRTTvdSVEGNASKILKMEKEnqrlsKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETlRENSERQIKILEQ 558
Cdd:pfam15921 543 LRNV--QTECEALKLQMAEKD-----KVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIND-RRLELQEFKILKD 614
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 559 ENEhlnqtvSSLRQrsqisAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKekgeraeeleNELHHLE 638
Cdd:pfam15921 615 KKD------AKIRE-----LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSR----------NELNSLS 673
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 639 KENELLQKKITN----LKITCEKIE-ALEQENSELERENRKLKK-----------TLDSFKNLTF---QLESLEKENSQL 699
Cdd:pfam15921 674 EDYEVLKRNFRNkseeMETTTNKLKmQLKSAQSELEQTRNTLKSmegsdghamkvAMGMQKQITAkrgQIDALQSKIQFL 753
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 700 DEENLELRRNVESLKCASMKMAQlqlENKELESEKEQLKKGLELLKAsfkKTERLEVSYQGLDIENQRLQKTLENSNKKI 779
Cdd:pfam15921 754 EEAMTNANKEKHFLKEEKNKLSQ---ELSTVATEKNKMAGELEVLRS---QERRLKEKVANMEVALDKASLQFAECQDII 827
|
650 660
....*....|....*....|..
gi 208022632 780 QQLESELQDLEMENQTLQKNLE 801
Cdd:pfam15921 828 QRQEQESVRLKLQHTLDVKELQ 849
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
252-1088 |
3.00e-11 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 69.05 E-value: 3.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEqmeielkrlqqenmnllsdarsarmyrDELDALREKAVRVDKLESEVSR 331
Cdd:pfam01576 223 QIAELQAQIAELRAQLAKKEEELQAALARLE---------------------------EETAQKNNALKKIRELEAQISE 275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 332 YKERLHDIEFYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLK------AKLHDMEME--RDMDR 402
Cdd:pfam01576 276 LQEDLESERAARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKkaleeeTRSHEAQLQemRQKHT 355
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 403 KKIEELMEE-------NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKT 475
Cdd:pfam01576 356 QALEELTEQleqakrnKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-QARLSESERQRAELAEK 434
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 476 VEELRTTVDSVEGNASkilKMEKENQRLSKKVEILENEivqekqsLQNCQNLSKDLMKEKAQLEktiETLRENSERQIKI 555
Cdd:pfam01576 435 LSKLQSELESVSSLLN---EAEGKNIKLSKDVSSLESQ-------LQDTQELLQEETRQKLNLS---TRLRQLEDERNSL 501
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 556 LEQENEHLNQTVSSLRQRSqiSAEARVKDIEKEnkilhesIKETSSKLSKIEFEKRQIKKELEhykEKGERAEELENELH 635
Cdd:pfam01576 502 QEQLEEEEEAKRNVERQLS--TLQAQLSDMKKK-------LEEDAGTLEALEEGKKRLQRELE---ALTQQLEEKAAAYD 569
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 636 HLEKENELLQKKITNLKItceKIEALEQENSELERENRKLKKTLDSFKNLTFQL---------ESLEKENSQLD-----E 701
Cdd:pfam01576 570 KLEKTKNRLQQELDDLLV---DLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerdraeaEAREKETRALSlaralE 646
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 702 ENLELRRNVESlkcaSMKMAQLQLEN-------------------KELESEKEQLKKGLELLKASFKKTE----RLEVSY 758
Cdd:pfam01576 647 EALEAKEELER----TNKQLRAEMEDlvsskddvgknvhelerskRALEQQVEEMKTQLEELEDELQATEdaklRLEVNM 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 759 QGLDIENQR-LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE--------QLEKENKSLEQETSQLEK 829
Cdd:pfam01576 723 QALKAQFERdLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQLKK 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 830 DK---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIyKESCVRLKELEKE-------NKELVKRATI 899
Cdd:pfam01576 803 LQaqmKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGASGKSALQ 881
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 900 DIK-----TLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIG--LNKERLLH----------DEQSTDDRYKL--LESKL 960
Cdd:pfam01576 882 DEKrrleaRIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTteLAAERSTSqksesarqqlERQNKELKAKLqeMEGTV 961
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 961 ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL-KTVKKNYEALKQRQDEERMVQssppisgednKWERESQETTRE 1039
Cdd:pfam01576 962 KSKFKSSIAALEAKIAQLEEQLEQESRERQAANKLVrRTEKKLKEVLLQVEDERRHAD----------QYKDQAEKGNSR 1031
|
890 900 910 920
....*....|....*....|....*....|....*....|....*....
gi 208022632 1040 LLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Cdd:pfam01576 1032 MKQLKRQLEEAEEEASRANAARRKLQRELDDATESNESMNREVSTLKSK 1080
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
201-669 |
4.93e-11 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 68.14 E-value: 4.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 201 IDERDEHSETIIELSEERDGLhflphasssaqspcgspGMKRTESRQHLSVELADAKAkIRRLRQELEEKTEQ----LLD 276
Cdd:PRK02224 271 EREREELAEEVRDLRERLEEL-----------------EEERDDLLAEAGLDDADAEA-VEARREELEDRDEElrdrLEE 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 277 CKQELEQMEIELKRLQQENMNLLSDARSARMYRDELD--------ALREKAVRVDKLESEVSRYKERLHDIEFYKARVEE 348
Cdd:PRK02224 333 CRVAAQAHNEEAESLREDADDLEERAEELREEAAELEseleeareAVEDRREEIEELEEEIEELRERFGDAPVDLGNAED 412
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 349 LKEDnqvLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDM-----------DRKKIEELMEENMTLEm 417
Cdd:PRK02224 413 FLEE---LREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVegsphvetieeDRERVEELEAELEDLE- 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 418 AQKQSMDESLHLGWEL-EQISRTSELSEapQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKilkM 496
Cdd:PRK02224 489 EEVEEVEERLERAEDLvEAEDRIERLEE--RREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAE---A 563
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSkDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQI 576
Cdd:PRK02224 564 EEEAEEAREEVAELNSKLAELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAE 642
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKenellqkkitnlkiTCE 656
Cdd:PRK02224 643 FDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALEN--------------RVE 708
|
490
....*....|...
gi 208022632 657 KIEALEQENSELE 669
Cdd:PRK02224 709 ALEALYDEAEELE 721
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
638-1075 |
5.83e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 67.49 E-value: 5.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 638 EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLkcas 717
Cdd:COG4717 53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL---- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 718 mkmaQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKI-QQLESELQDLEMENQTL 796
Cdd:COG4717 129 ----PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEEL 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 797 QKNLEELKissKRLEQLEKENKSLEQETSQLEkDKKQLEKENKRLRQQAEI------------KDTTLEENNVKIGN--- 861
Cdd:COG4717 205 QQRLAELE---EELEEAQEELEELEEELEQLE-NELEAAALEERLKEARLLlliaaallallgLGGSLLSLILTIAGvlf 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 862 ------------LEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLT 929
Cdd:COG4717 281 lvlgllallfllLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELE 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 930 HELEKIGLNKER--LLHDEQSTDDryKLLESKLEstLKKSLEIKEEKIAALEARLEESTNYNQ---------QLRQELKT 998
Cdd:COG4717 361 EELQLEELEQEIaaLLAEAGVEDE--EELRAALE--QAEEYQELKEELEELEEQLEELLGELEellealdeeELEEELEE 436
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 208022632 999 VKKNYEALKQRQDEERMVQSSppISGEDNKWE--RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN 1075
Cdd:COG4717 437 LEEELEELEEELEELREELAE--LEAELEQLEedGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
136-847 |
5.93e-11 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 68.07 E-value: 5.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 136 QKKEEFIERIQGLD-FDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMSQEDIEPL---LKNMALHLKRLIDERDEHSETI 211
Cdd:TIGR00618 163 KEKKELLMNLFPLDqYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYherKQVLEKELKHLREALQQTQQSH 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 212 IELSEERDGLHflphASSSAQSPCGSPgMKRTESRQHLSVELADAKAKIRRLRQ--ELEEKTEQLLDCKQELEQMEIELK 289
Cdd:TIGR00618 243 AYLTQKREAQE----EQLKKQQLLKQL-RARIEELRAQEAVLEETQERINRARKaaPLAAHIKAVTQIEQQAQRIHTELQ 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 290 RLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEG 369
Cdd:TIGR00618 318 SKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQS 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 370 TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDeslhlgwelEQISRTSELSEAPQKS 449
Cdd:TIGR00618 398 LCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQ---------CEKLEKIHLQESAQSL 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 450 LGHEVNELTSSRLLKLEMEnqslTKTVEElrttvdsvegnasKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 529
Cdd:TIGR00618 469 KEREQQLQTKEQIHLQETR----KKAVVL-------------ARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQ 531
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 530 DLMKEKAQLEKTIETLRE--NSER-QIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Cdd:TIGR00618 532 RGEQTYAQLETSEEDVYHqlTSERkQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLA 611
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 607 EfEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEAL---EQENSELERENRKLKKTLDSFK 683
Cdd:TIGR00618 612 C-EQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALsirVLPKELLASRQLALQKMQSEKE 690
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 684 NLTFQLESLEKENSQLDEEN---LELRRNVESLKCASMKM-----AQLQLENKELESEKEQLKKGL-ELLKASFKKTERL 754
Cdd:TIGR00618 691 QLTYWKEMLAQCQTLLRELEthiEEYDREFNEIENASSSLgsdlaAREDALNQSLKELMHQARTVLkARTEAHFNNNEEV 770
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 755 EVSYQgLDIENQRLQKTLENSNKKIQQLESELQDLEMENQT------LQKNLEELKISSKR---LEQLEKENKSLEQETS 825
Cdd:TIGR00618 771 TAALQ-TGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQeipsdeDILNLQCETLVQEEeqfLSRLEEKSATLGEITH 849
|
730 740
....*....|....*....|..
gi 208022632 826 QLEKDKKQLEKENKRLRQQAEI 847
Cdd:TIGR00618 850 QLLKYEECSKQLAQLTQEQAKI 871
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
261-1123 |
6.20e-11 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 67.89 E-value: 6.20e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARsarmyrDELDALREKAVRVDKLESEVSRYKERLHDIE 340
Cdd:pfam01576 211 RKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLE------EETAQKNNALKKIRELEAQISELQEDLESER 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 341 FYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDKLHELEKENLQLK------AKLHDMEME--RDMDRKKIEELMEE 411
Cdd:pfam01576 285 AARNKAEKQRRDLGEELEAlKTELEDTLDTTAAQQELRSKREQEVTELKkaleeeTRSHEAQLQemRQKHTQALEELTEQ 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 412 -------NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEELRTTVD 484
Cdd:pfam01576 365 leqakrnKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQEL-QARLSESERQRAELAEKLSKLQSELE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 485 SVEGNASKIlkmEKENQRLSKKVEILENEivqekqsLQNCQNLSKDLMKEKAQLEKTietLRENSERQIKILEQENEHLN 564
Cdd:pfam01576 444 SVSSLLNEA---EGKNIKLSKDVSSLESQ-------LQDTQELLQEETRQKLNLSTR---LRQLEDERNSLQEQLEEEEE 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 565 QTVSSLRQRSqiSAEARVKDIEKEnkilhesIKETSSKLSKIEFEKRQIKKELEhykEKGERAEELENELHHLEKENELL 644
Cdd:pfam01576 511 AKRNVERQLS--TLQAQLSDMKKK-------LEEDAGTLEALEEGKKRLQRELE---ALTQQLEEKAAAYDKLEKTKNRL 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 645 QKKITNLKItceKIEALEQENSELERENRKLKKTLDSFKNLTFQL---------ESLEKENSQLD-----EENLELRRNV 710
Cdd:pfam01576 579 QQELDDLLV---DLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYaeerdraeaEAREKETRALSlaralEEALEAKEEL 655
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 711 ESlkcaSMKMAQLQLEN-------------------KELESEKEQLKKGLELLKASFKKTE----RLEVSYQGLDIENQR 767
Cdd:pfam01576 656 ER----TNKQLRAEMEDlvsskddvgknvhelerskRALEQQVEEMKTQLEELEDELQATEdaklRLEVNMQALKAQFER 731
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 768 -LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE--------QLEKENKSLEQETSQLEKDK---KQLE 835
Cdd:pfam01576 732 dLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLEldlkeleaQIDAANKGREEAVKQLKKLQaqmKDLQ 811
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 836 KENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIyKESCVRLKELEKE-------NKELVKRATIDIK-----T 903
Cdd:pfam01576 812 RELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAA-SERARRQAQQERDeladeiaSGASGKSALQDEKrrleaR 890
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKigLNKErlLHDEQSTDDRYKLLESKLESTLKKsleikeekiaaLEARLE 983
Cdd:pfam01576 891 IAQLEEELEEEQSNTELLNDRLRKSTLQVEQ--LTTE--LAAERSTSQKSESARQQLERQNKE-----------LKAKLQ 955
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 984 EstnYNQQLRQELKTVKKNYEAlKQRQDEERMVQSSppisgednkweRESQETTRELLKVKDRLIEVernnaTLQAEKQa 1063
Cdd:pfam01576 956 E---MEGTVKSKFKSSIAALEA-KIAQLEEQLEQES-----------RERQAANKLVRRTEKKLKEV-----LLQVEDE- 1014
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 208022632 1064 lKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVE-------NSTLNSQSTSLMNQ 1123
Cdd:pfam01576 1015 -RRHADQYKDQAEKGNSRMKQLKRQLEEAEEEASRANAARRKLQRElddatesNESMNREVSTLKSK 1080
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
252-1012 |
7.22e-11 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 67.76 E-value: 7.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMyRDELDALREKAVRVDKLESEVSR 331
Cdd:TIGR00606 320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLAT-RLELDGFERGPFSERQIKNFHTL 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 332 YKERLHDIEFYKAR-VEELKEDNQVLLETKTMLEDQLEGT-RARSDKLHELEKENLQLKAKLHDME-MERDMDR--KKIE 406
Cdd:TIGR00606 399 VIERQEDEAKTAAQlCADLQSKERLKQEQADEIRDEKKGLgRTIELKKEILEKKQEELKFVIKELQqLEGSSDRilELDQ 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 407 ELMEENMTLEMAQKQSMDESL-----HLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL--KLEMENQSLTKTVEEL 479
Cdd:TIGR00606 479 ELRKAERELSKAEKNSLTETLkkevkSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLtkDKMDKDEQIRKIKSRH 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 480 RTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN------SERQI 553
Cdd:TIGR00606 559 SDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEE 638
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 554 KILEQENEHLNQtvsSLRQRSQISAEARVKDiekenKILHESIKETSS------KLSKIEFEKRQIKKELEH-YKEKGER 626
Cdd:TIGR00606 639 SDLERLKEEIEK---SSKQRAMLAGATAVYS-----QFITQLTDENQSccpvcqRVFQTEAELQEFISDLQSkLRLAPDK 710
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 627 AEELENELHHLEKENELLqkkITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNltfqleSLEKENSQLDEENLEL 706
Cdd:TIGR00606 711 LKSTESELKKKEKRRDEM---LGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKN------DIEEQETLLGTIMPEE 781
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 707 RrNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASF------KKTERLEVSYQGLDIENQRLQKTLENSNKKIQ 780
Cdd:TIGR00606 782 E-SAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRtvqqvnQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQ 860
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 781 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQqaeikdttleENNVKIG 860
Cdd:TIGR00606 861 HLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQ----------EKEELIS 930
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 861 NLEKENKTLSKEIGIYKESCVR----LKELEKENKELVKRATIDIKT-LVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:TIGR00606 931 SKETSNKKAQDKVNDIKEKVKNihgyMKDIENKIQDGKDDYLKQKETeLNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ 1010
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 936 GLnKERLLHDEqstddrykLLESKLESTLKkslEIKEEKIAAL----EARLEESTNYNQQLRQELKTVKKNYEALKQRQD 1011
Cdd:TIGR00606 1011 KI-QERWLQDN--------LTLRKRENELK---EVEEELKQHLkemgQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQK 1078
|
.
gi 208022632 1012 E 1012
Cdd:TIGR00606 1079 G 1079
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
434-1044 |
7.69e-11 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 67.44 E-value: 7.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 434 EQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQ--SLTKTVEELRTTVDSVEGNAskilKMEKEN-QRLSKKVEIL 510
Cdd:pfam05483 219 EDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKmkDLTFLLEESRDKANQLEEKT----KLQDENlKELIEKKDHL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENE-------HLNQTVSSLRQRSQiSAEARVK 583
Cdd:pfam05483 295 TKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAahsfvvtEFEATTCSLEELLR-TEQQRLE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITcekIEALEQ 663
Cdd:pfam05483 374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFL---LQAREK 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 664 ENSELEREnrkLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVEslkcasmkmaQLQLENKELESEKEQLKkglel 743
Cdd:pfam05483 451 EIHDLEIQ---LTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCD----------KLLLENKELTQEASDMT----- 512
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 744 lkasfkkterLEVSYQGLDIENQRLQKtlENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK-RLEQLEKENKSLEQ 822
Cdd:pfam05483 513 ----------LELKKHQEDIINCKKQE--ERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKcKLDKSEENARSIEY 580
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 823 ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLkELEKENKELVKRATIDik 902
Cdd:pfam05483 581 EVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKL-ELELASAKQKFEEIID-- 657
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 903 tlvTLREDLVSEKLKTQQMNNDLEKLTHEL-EKIGLNKERLLHDEQSTDDRYKLLEsKLESTLKKSLEIKEEKIAALEAR 981
Cdd:pfam05483 658 ---NYQKEIEDKKISEEKLLEEVEKAKAIAdEAVKLQKEIDKRCQHKIAEMVALME-KHKHQYDKIIEERDSELGLYKNK 733
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 208022632 982 LEESTNYNQQLRQELKTVKKNYEALKQRQDEERMvqssppisgEDNKWERESQETTRELLKVK 1044
Cdd:pfam05483 734 EQEQSSAKAALEIELSNIKAELLSLKKQLEIEKE---------EKEKLKMEAKENTAILKDKK 787
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
625-1009 |
9.66e-11 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 66.71 E-value: 9.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 625 ERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLdsfknltfQLESLEKENSQLDEENL 704
Cdd:COG4717 71 KELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL--------QLLPLYQELEALEAELA 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 705 ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVsyqgldienQRLQKTLENSNKKIQQLES 784
Cdd:COG4717 143 ELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEEL---------QDLAEELEELQQRLAELEE 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 785 ELQDLEMENQTLQKNLEELKISSKRLEQLEKENK--------------------------------------------SL 820
Cdd:COG4717 214 ELEEAQEELEELEEELEQLENELEAAALEERLKEarlllliaaallallglggsllsliltiagvlflvlgllallflLL 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 821 EQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID 900
Cdd:COG4717 294 AREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 901 ---IKTLVTLREDLVS---EKLKTQQMNNDLEKLTHELEKIGLNKERLL--HDEQSTDDRYKLLESKLEStLKKSLEIKE 972
Cdd:COG4717 374 allAEAGVEDEEELRAaleQAEEYQELKEELEELEEQLEELLGELEELLeaLDEEELEEELEELEEELEE-LEEELEELR 452
|
410 420 430
....*....|....*....|....*....|....*....
gi 208022632 973 EKIAALEARLE--ESTNYNQQLRQELKTVKKNYEALKQR 1009
Cdd:COG4717 453 EELAELEAELEqlEEDGELAELLQELEELKAELRELAEE 491
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
585-1240 |
1.21e-10 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 66.67 E-value: 1.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 585 IEKENKILHESIKETSSKLS---KIEFEKRQIKKELEHYKEK-GERAEELENELHHLEKENELLQKKITNLKITCEKiEA 660
Cdd:pfam05483 90 IKKWKVSIEAELKQKENKLQenrKIIEAQRKAIQELQFENEKvSLKLEEEIQENKDLIKENNATRHLCNLLKETCAR-SA 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 661 LEQENSELERE---------NRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVES--LKCASMKMAQLQLENKE 729
Cdd:pfam05483 169 EKTKKYEYEREetrqvymdlNNNIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEeyKKEINDKEKQVSLLLIQ 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 730 LESEKEQLKKGLELLKASFKKTERLEvsyqgldiENQRLQ-KTLENSNKKIQQLESELQDLEMENQ---TLQKNLEE-LK 804
Cdd:pfam05483 249 ITEKENKMKDLTFLLEESRDKANQLE--------EKTKLQdENLKELIEKKDHLTKELEDIKMSLQrsmSTQKALEEdLQ 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 805 ISSKRLEQLEKENKSLEQETSQLEKDKK----QLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIgiykESC 880
Cdd:pfam05483 321 IATKTICQLTEEKEAQMEELNKAKAAHSfvvtEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSEL----EEM 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 881 VRLKElekeNKELVKRatiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE--- 957
Cdd:pfam05483 397 TKFKN----NKEVELE---ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEehy 469
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 958 SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQE-----LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERE 1032
Cdd:pfam05483 470 LKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEasdmtLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDE 549
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1033 SQETTRELLK----VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQ----TQNA 1104
Cdd:pfam05483 550 LESVREEFIQkgdeVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKkkgsAENK 629
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1105 KLQVENSTLNSQSTSL---------MNQNAQLLIQQSSLENENesVIKEREDLKSLYDSLIKDHEKLEL----------- 1164
Cdd:pfam05483 630 QLNAYEIKVNKLELELasakqkfeeIIDNYQKEIEDKKISEEK--LLEEVEKAKAIADEAVKLQKEIDKrcqhkiaemva 707
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1165 LHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYN-QLLKQKGQLEDLEKMLKV---EQEKMLLENKNHETVAAEYK 1240
Cdd:pfam05483 708 LMEKHKHQYDKIIEERDSELGLYKNKEQEQSSAKAALEiELSNIKAELLSLKKQLEIekeEKEKLKMEAKENTAILKDKK 787
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
263-586 |
1.25e-10 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 66.25 E-value: 1.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 263 LRQELEEKTEQLL-------DCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKER 335
Cdd:pfam05622 64 LQKQLEQLQEENFrletardDYRIKCEELEKEVLELQHRNEELTSLAEEAQALKDEMDILRESSDKVKKLEATVETYKKK 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 336 LHDIEFYKARVEELKEDNQVLLETKTMLED----------QLEGTRARSDKLH-----------ELEKENLQLKAKLHDM 394
Cdd:pfam05622 144 LEDLGDLRRQVKLLEERNAEYMQRTLQLEEelkkanalrgQLETYKRQVQELHgklseeskkadKLEFEYKKLEEKLEAL 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 395 EMERDMDRKKIEELMEENMTLEMAQKQSMdeslhlgwELEQISRTSELSEAPQKSLGHEVNEL-TSSRLLKLEMENQSL- 472
Cdd:pfam05622 224 QKEKERLIIERDTLRETNEELRCAQLQQA--------ELSQADALLSPSSDPGDNLAAEIMPAeIREKLIRLQHENKMLr 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 473 ---TKTVEELRTTVDSVEGNASKIL-KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE- 547
Cdd:pfam05622 296 lgqEGSYRERLTELQQLLEDANRRKnELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLEEHLEKLHEa 375
|
330 340 350
....*....|....*....|....*....|....*....
gi 208022632 548 NSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIE 586
Cdd:pfam05622 376 QSELQKKKEQIEELEPKQDSNLAQKIDELQEALRKKDED 414
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
241-559 |
2.01e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 66.23 E-value: 2.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREK-A 319
Cdd:TIGR02168 667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQlE 746
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 320 VRVDKLESEVSRYKERlhdIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRAR----SDKLHELEKENLQLKAKLHDME 395
Cdd:TIGR02168 747 ERIAQLSKELTELEAE---IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEElkalREALDELRAELTLLNEEAANLR 823
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 396 MERDMDRKKIEELMEEnmtLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSsrllkLEMENQSLTKT 475
Cdd:TIGR02168 824 ERLESLERRIAATERR---LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS-----LEEALALLRSE 895
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 476 VEELRTTVDSVEgnaSKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQ----NLSKDLMKEKAQLEKTIETLRENSER 551
Cdd:TIGR02168 896 LEELSEELRELE---SKRSELRRELEELREKLAQLELRLEGLEVRIDNLQerlsEEYSLTLEEAEALENKIEDDEEEARR 972
|
....*...
gi 208022632 552 QIKILEQE 559
Cdd:TIGR02168 973 RLKRLENK 980
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1035-1370 |
2.41e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 65.73 E-value: 2.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1035 ETTRE-LLKVKDRLIEVERNNATL--QAEK----QALKTQLKQLEtqnnnlqAQILALQRQTVSLQeqnttLQTQNAKLQ 1107
Cdd:COG1196 182 EATEEnLERLEDILGELERQLEPLerQAEKaeryRELKEELKELE-------AELLLLKLRELEAE-----LEELEAELE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1108 VENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYEsliskhgTLKSAH 1187
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEE-------RLEELE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1188 KNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDH 1267
Cdd:COG1196 323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1268 KNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmLQNRTLLEQNMES 1347
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL-LEEAALLEAALAE 481
|
330 340
....*....|....*....|...
gi 208022632 1348 KDLFHVEQRQYIDKLNELRRQKE 1370
Cdd:COG1196 482 LLEELAEAAARLLLLLEAEADYE 504
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
419-1052 |
2.57e-10 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 65.69 E-value: 2.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 419 QKQSMDESLhlgwELEQISRTSELSEAPQKSLGHEVneltsSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKmek 498
Cdd:PRK01156 151 RKKILDEIL----EINSLERNYDKLKDVIDMLRAEI-----SNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLK--- 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 499 ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL-RQRSQIS 577
Cdd:PRK01156 219 EIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVyKNRNYIN 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 578 AEARVK-DIEKENKILhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNlkitce 656
Cdd:PRK01156 299 DYFKYKnDIENKKQIL-SNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKS------ 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 657 kieaLEQENSELERENRKLKKTLDsfknltFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Cdd:PRK01156 372 ----IESLKKKIEEYSKNIERMSA------FISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDE 441
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 737 LKKGLELLKAsfkkteRLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKE 816
Cdd:PRK01156 442 LSRNMEMLNG------QSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLK---KRKEYLESE 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 817 N-KSLEQETSQLEKDKKQLEKEnkrlrqqaEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEscvrlkelEKENKELVK 895
Cdd:PRK01156 513 EiNKSINEYNKIESARADLEDI--------KIKINELKDKHDKYEEIKNRYKSLKLEDLDSKR--------TSWLNALAV 576
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 896 RATIDIKTLVTlREDLVSEKLktqqmnNDLEKLTHELEKiglnkeRLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKI 975
Cdd:PRK01156 577 ISLIDIETNRS-RSNEIKKQL------NDLESRLQEIEI------GFPDDKSYIDKSIREIENEANNLNNKYNEIQENKI 643
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 208022632 976 AAlearleestnynQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVER 1052
Cdd:PRK01156 644 LI------------EKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILR 708
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
262-1250 |
2.61e-10 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 65.97 E-value: 2.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSdarsarmyrdeldalrEKAVRVDKLESEVSRYKERlhdiEF 341
Cdd:pfam01576 2 RQEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCE----------------EKNALQEQLQAETELCAEA----EE 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 342 YKARVEELKednQVLLETKTMLEDQLEGTRARSDKLHELEKEnlqLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ 421
Cdd:pfam01576 62 MRARLAARK---QELEEILHELESRLEEEEERSQQLQNEKKK---MQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKK 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 422 SMDESLHLGWELEQISRTselseapQKSLGHEVNELTSSrLLKLEMENQSLTKTVEELRTTVDSVEGnasKILKMEKENQ 501
Cdd:pfam01576 136 LEEDILLLEDQNSKLSKE-------RKLLEERISEFTSN-LAEEEEKAKSLSKLKNKHEAMISDLEE---RLKKEEKGRQ 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 502 RLSKKVEILENEIVQEKQSLQNCQNLSKDLmkeKAQLEKTIETLRENSERqikiLEQENEHLNQTVSSLRQrsqisAEAR 581
Cdd:pfam01576 205 ELEKAKRKLEGESTDLQEQIAELQAQIAEL---RAQLAKKEEELQAALAR----LEEETAQKNNALKKIRE-----LEAQ 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 582 VKDiekenkiLHESIKETSSKLSKIEFEKRQIKKELEHYKEkgeraeELENELHHLEKENELLQKK---ITNLKitceki 658
Cdd:pfam01576 273 ISE-------LQEDLESERAARNKAEKQRRDLGEELEALKT------ELEDTLDTTAAQQELRSKReqeVTELK------ 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 659 EALEQENSELERENRKL-KKTLDSFKNLTFQLE-------SLEKENSQLDEENLELRRNVESLKCASMkmaqlqlenkEL 730
Cdd:pfam01576 334 KALEEETRSHEAQLQEMrQKHTQALEELTEQLEqakrnkaNLEKAKQALESENAELQAELRTLQQAKQ----------DS 403
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 731 ESEKEQLKKGLELLKASFKKTER----LEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEE---- 802
Cdd:pfam01576 404 EHKRKKLEGQLQELQARLSESERqraeLAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEetrq 483
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 803 -LKISSkRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGI----YK 877
Cdd:pfam01576 484 kLNLST-RLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEAltqqLE 562
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 878 ESCVRLKELEKENKELVKRAtidiktlvtlrEDLVSEKLKTQQMNNDLEKLTHELEKiglnkerLLHDEQSTDDRYKLLE 957
Cdd:pfam01576 563 EKAAAYDKLEKTKNRLQQEL-----------DDLLVDLDHQRQLVSNLEKKQKKFDQ-------MLAEEKAISARYAEER 624
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 958 SKLESTLKKsleiKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEerMVQSSPPISGEDNKWERESQETT 1037
Cdd:pfam01576 625 DRAEAEARE----KETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDD--VGKNVHELERSKRALEQQVEEMK 698
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1038 RELLKVKDRLIEVERNNATLQAEKQALKTQL--------KQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVE 1109
Cdd:pfam01576 699 TQLEELEDELQATEDAKLRLEVNMQALKAQFerdlqardEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELD 778
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1110 NSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKN 1189
Cdd:pfam01576 779 LKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQ 858
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 208022632 1190 LEVEHRDLEDRYNQLLKQKGQLED----LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLN 1250
Cdd:pfam01576 859 AQQERDELADEIASGASGKSALQDekrrLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLT 923
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
456-877 |
2.91e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 65.17 E-value: 2.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 456 ELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEK--QSLQNCQNLSKDLMK 533
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 534 EKAQLEKTIETLRENsERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQI 613
Cdd:COG4717 147 RLEELEERLEELREL-EEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 614 KKELEHYKEKGERAEELEnELHHLE--------------KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTL 679
Cdd:COG4717 226 EEELEQLENELEAAALEE-RLKEARlllliaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 680 DSFKNLTfQLESLEKE--NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKkglelLKASFKKTERLEVS 757
Cdd:COG4717 305 EELQALP-ALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ-----LEELEQEIAALLAE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 758 YQGLDIE----NQRLQKTLENSNKKIQQLESELQDL--EMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:COG4717 379 AGVEDEEelraALEQAEEYQELKEELEELEEQLEELlgELEELLEALDEEELE---EELEELEEELEELEEELEELREEL 455
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 208022632 832 KQLEKENKRLRqqaeiKDTTLEENNVKIGNLEKENKTLSKEIGIYK 877
Cdd:COG4717 456 AELEAELEQLE-----EDGELAELLQELEELKAELRELAEEWAALK 496
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
259-695 |
4.61e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.79 E-value: 4.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 259 KIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAvrvdKLESEVSRYKERLHD 338
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELE----ALEAELAELPERLEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 339 IEFYKARVEELKEDNQVLLETKTMLEDQLEgtRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEmA 418
Cdd:COG4717 151 LEERLEELRELEEELEELEAELAELQEELE--ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE-E 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 419 QKQSMDESLHLGWELEQISRTSELSEAPQKSLGHevnELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEK 498
Cdd:COG4717 228 ELEQLENELEAAALEERLKEARLLLLIAAALLAL---LGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 499 ENQRLSKKVEILENEIVQE-KQSLQNCQNLSKDLMKEK-AQLEKTIETLRENSERQIKILEQENEHlnqtvsslrQRSQI 576
Cdd:COG4717 305 EELQALPALEELEEEELEElLAALGLPPDLSPEELLELlDRIEELQELLREAEELEEELQLEELEQ---------EIAAL 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 577 SAEARVKDIEKENKIL--HESIKETSSKLSKIEFEKRQIKKELEHYKEKGERaEELENELHHLEKENELLQKKITNLKit 654
Cdd:COG4717 376 LAEAGVEDEEELRAALeqAEEYQELKEELEELEEQLEELLGELEELLEALDE-EELEEELEELEEELEELEEELEELR-- 452
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 208022632 655 cEKIEALEQENSELERENRkLKKTLDSFKNLTFQLESLEKE 695
Cdd:COG4717 453 -EELAELEAELEQLEEDGE-LAELLQELEELKAELRELAEE 491
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
729-1116 |
5.16e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.70 E-value: 5.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 729 ELESEKEqlkKGLELLKASFKKTERLEVSyqgLDIENQRLQKTLENSNKKI--QQLESELQDLEmenqtlqknleeLKIS 806
Cdd:TIGR02169 167 EFDRKKE---KALEELEEVEENIERLDLI---IDEKRQQLERLRREREKAEryQALLKEKREYE------------GYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 807 SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL-EKENKTLSKEIGIYKESCVRLKE 885
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLER 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 886 LEKENKELVKRATIDIKTLVTLREDLVSEKlktqqmnndlEKLTHELEkiglnkerllhdeqstddRYKLLESKLESTLK 965
Cdd:TIGR02169 309 SIAEKERELEDAEERLAKLEAEIDKLLAEI----------EELEREIE------------------EERKRRDKLTEEYA 360
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 966 KsleiKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEermvqssppISGEDNKWERESQETTRELLKVKD 1045
Cdd:TIGR02169 361 E----LKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE---------LKRELDRLQEELQRLSEELADLNA 427
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 208022632 1046 RLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQ 1116
Cdd:TIGR02169 428 AIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ 498
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1025-1287 |
7.11e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.19 E-value: 7.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1025 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA-------QILALQRQTVSLQEQNT 1097
Cdd:COG1196 233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAeeyellaELARLEQDIARLEERRR 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1098 TLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLI 1177
Cdd:COG1196 313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1178 SKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKmllENKNHETVAAEYKKLCGENDRLNHTYSQLL 1257
Cdd:COG1196 393 RAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEE---EEEALEEAAEEEAELEEEEEALLELLAELL 469
|
250 260 270
....*....|....*....|....*....|
gi 208022632 1258 KETEVLQTDHKNLKSLLNNSKLEQTRLEAE 1287
Cdd:COG1196 470 EEAALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
688-1218 |
7.89e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 64.29 E-value: 7.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 688 QLESLEKENSQLDEENLelrrnVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKasfkktERLEvSYQGLDIENQR 767
Cdd:PRK02224 188 SLDQLKAQIEEKEEKDL-----HERLNGLESELAELDEEIERYEEQREQARETRDEAD------EVLE-EHEERREELET 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 768 LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL------------------KISSKRLEQLEKENKSLEQETSQLEK 829
Cdd:PRK02224 256 LEAEIEDLRETIAETEREREELAEEVRDLRERLEELeeerddllaeaglddadaEAVEARREELEDRDEELRDRLEECRV 335
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 830 DKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEscvRLKELEKENKELVKR---ATIDIKTLVT 906
Cdd:PRK02224 336 AAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRRE---EIEELEEEIEELRERfgdAPVDLGNAED 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL----------------HDEQSTDDRYKL--LESKLEStLKKSL 968
Cdd:PRK02224 413 FLEELREERDELREREAELEATLRTARERVEEAEALLeagkcpecgqpvegspHVETIEEDRERVeeLEAELED-LEEEV 491
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 969 EIKEEKIAALEArLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERESQETTRELLKVKDRLI 1048
Cdd:PRK02224 492 EEVEERLERAED-LVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE--LRERAAELEAEAEEKREAAAEAEEEAE 568
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1049 EVERNNATLQAEKQALKTQLKQLETQnNNLQAQILALQRQTVSLQEQNTTLQTQNA------------KLQVENSTLNSQ 1116
Cdd:PRK02224 569 EAREEVAELNSKLAELKERIESLERI-RTLLAAIADAEDEIERLREKREALAELNDerrerlaekrerKRELEAEFDEAR 647
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1117 STSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQaseyESLISKHGTLKSAHKNLEvehrD 1196
Cdd:PRK02224 648 IEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERR----EALENRVEALEALYDEAE----E 719
|
570 580
....*....|....*....|....*
gi 208022632 1197 LEDRYNQL---LKQKgQLEDLEKML 1218
Cdd:PRK02224 720 LESMYGDLraeLRQR-NVETLERML 743
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
203-872 |
1.04e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 64.01 E-value: 1.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 203 ERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTES-RQHLSVELADAKAKIRRLRQELEE--KTEQLLDCKQ 279
Cdd:PTZ00121 1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEkKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAE 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 280 ELEQMEIELKRLQQENMNLLSDARS-ARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELK----EDNQ 354
Cdd:PTZ00121 1326 EAKKKADAAKKKAEEAKKAAEAAKAeAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKkkaeEDKK 1405
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 355 VLLETKTMLEDQLEGTRARsdKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELE 434
Cdd:PTZ00121 1406 KADELKKAAAAKKKADEAK--KKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK 1483
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 435 QISRTSELSEAPQKSlghevneltSSRLLKLEMENqsltKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEI 514
Cdd:PTZ00121 1484 KADEAKKKAEEAKKK---------ADEAKKAAEAK----KKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE 1550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 515 VQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHE 594
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE 1630
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 595 SIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQENSElERENRK 674
Cdd:PTZ00121 1631 EKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEK---KAAEALKKEAEE-AKKAEE 1706
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 675 LKKTLDSFKNLTFQLESLEKENSQLDEenlELRRNVESLKcasmKMAQlQLENKELESEKEQLKKGLELLKASFKKTERL 754
Cdd:PTZ00121 1707 LKKKEAEEKKKAEELKKAEEENKIKAE---EAKKEAEEDK----KKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 755 EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQL 834
Cdd:PTZ00121 1779 AVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNN 1858
|
650 660 670
....*....|....*....|....*....|....*...
gi 208022632 835 EKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Cdd:PTZ00121 1859 ENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKD 1896
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
533-878 |
1.43e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 63.22 E-value: 1.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 533 KEKAQLEKTIETLRENSERQIKileqENEHLNQTVSSLRQRSQISAEARVKDIE------KENKILHESIKETSSKLSKI 606
Cdd:pfam05557 27 RARIELEKKASALKRQLDRESD----RNQELQKRIRLLEKREAEAEEALREQAElnrlkkKYLEALNKKLNEKESQLADA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 607 EFEKRQIKKELEHYKEKGERAE----ELENELHHLEKENELLQKKITNLKITCEKIEALEQENS-------ELERENRKL 675
Cdd:pfam05557 103 REVISCLKNELSELRRQIQRAElelqSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQSSLAeaeqrikELEFEIQSQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 676 KKTLDSFKNLTFQLES---LEKENSQLDEENLELRRNVESlkcasmkmaqlqleNKELESEKEQLKKGLELLKASFKKTE 752
Cdd:pfam05557 183 EQDSEIVKNSKSELARipeLEKELERLREHNKHLNENIEN--------------KLLLKEEVEDLKRKLEREEKYREEAA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 753 RLEVsyqgldienqrlqktlensnkKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK-------SLEQETS 825
Cdd:pfam05557 249 TLEL---------------------EKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIvlkeensSLTSSAR 307
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 208022632 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKE 878
Cdd:pfam05557 308 QLEKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRA 360
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
521-873 |
1.49e-09 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 62.61 E-value: 1.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 521 LQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAE--ARVKDIEKENKILHESIKE 598
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREkhEELEEKYKELSASSEELSE 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 599 TSSKLSKIEFEKRQIKKELEH-YKEKGERAEELENELHHLEKEnellQKKITNLKitcekiealEQENSELERENRKLKK 677
Cdd:pfam07888 116 EKDALLAQRAAHEARIRELEEdIKTLTQRVLERETELERMKER----AKKAGAQR---------KEEEAERKQLQAKLQQ 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 678 TLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVS 757
Cdd:pfam07888 183 TEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLT---QKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEE 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 758 YQGLDIENQRLQKTLENSNKKIQQLESELQDLEM-----------ENQTLQKNLEELKISSKRL-EQLEKENKSLEQETS 825
Cdd:pfam07888 260 LSSMAAQRDRTQAELHQARLQAAQLTLQLADASLalregrarwaqERETLQQSAEADKDRIEKLsAELQRLEERLQEERM 339
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 208022632 826 QLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Cdd:pfam07888 340 EREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEK 387
|
|
| HkD_Hook1 |
cd22225 |
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a ... |
18-163 |
2.44e-09 |
|
Hook domain found in protein Hook 1 (Hook1) and similar proteins; Hook1 is a microtubule-binding protein required for spermatid differentiation. It is a component of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex.
Pssm-ID: 411796 Cd Length: 150 Bit Score: 57.94 E-value: 2.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 18 LVTWVKTFGPLAAGNGTNldeyvALVDGVFLNQVMLQINPKLESQ----RVNKKVNNDASLRMHNLSILVRQIKFYYQET 93
Cdd:cd22225 5 LIIWLQTFNTAAPCQTVQ-----DLTSGVAMAQVLHQIDSSWFDEswlsRIKEDVGDNWRIKMSNLKKILQGIVDYYHEF 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 208022632 94 L-QQLIMMSLPNVliigkNPFSEQGTE-EVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEV 163
Cdd:cd22225 80 LdQQISEFLLPDL-----NRIAEHSDPvELGRLLQLILGCAVNCEKKQEHIQNIMTLEESVQHVVMTAIQEL 146
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
436-1323 |
2.66e-09 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 62.85 E-value: 2.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 436 ISRTSELSEapqksLGHEVNELTSSRLLKLEMENQSLTKTveELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIV 515
Cdd:PTZ00121 1026 IEKIEELTE-----YGNNDDVLKEKDIIDEDIDGNHEGKA--EAKAHVGQDEGLKPSYKDFDFDAKEDNRADEATEEAFG 1098
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 516 QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENkilhES 595
Cdd:PTZ00121 1099 KAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKA----ED 1174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 596 IKETSSKLSKIEFEKRQIKKELEHYKeKGERAEELENELHHLEKENELLQKKITNLKITCE-KIEALEQENSELERENRK 674
Cdd:PTZ00121 1175 AKKAEAARKAEEVRKAEELRKAEDAR-KAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEaKKDAEEAKKAEEERNNEE 1253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 675 LKKTLDSFKNLTFQLESLEKENSQLDEEnlELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKasfkKTERL 754
Cdd:PTZ00121 1254 IRKFEEARMAHFARRQAAIKAEEARKAD--ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKK----KAEEA 1327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 755 EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQL 834
Cdd:PTZ00121 1328 KKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKA 1407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 835 EkenkrlrqqaEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSE 914
Cdd:PTZ00121 1408 D----------ELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKK 1477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 915 KLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSleikEEKIAALEARLEESTNYNQQLR- 993
Cdd:PTZ00121 1478 KAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKA----EEAKKADEAKKAEEKKKADELKk 1553
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 994 -QELKTVKKNYEALKQRQDEERmvqssppisgeDNKWERESQETtrellkvkdRLIEVERNNATLQAEKQALKTQLKQLE 1072
Cdd:PTZ00121 1554 aEELKKAEEKKKAEEAKKAEED-----------KNMALRKAEEA---------KKAEEARIEEVMKLYEEEKKMKAEEAK 1613
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1073 TQNnnlQAQILALQ-RQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSL 1151
Cdd:PTZ00121 1614 KAE---EAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKA 1690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1152 YDSLIKDHE---KLELLHERQASEY---ESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKM 1225
Cdd:PTZ00121 1691 AEALKKEAEeakKAEELKKKEAEEKkkaEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKA 1770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1226 LLENKNHETVAAEYKKLCGENDRL--NHTYSQLLKETEVLQTDHKNLKSLLNNSKleqtrlEAEFSKLKEqyqqLDITST 1303
Cdd:PTZ00121 1771 EEIRKEKEAVIEEELDEEDEKRRMevDKKIKDIFDNFANIIEGGKEGNLVINDSK------EMEDSAIKE----VADSKN 1840
|
890 900
....*....|....*....|
gi 208022632 1304 KLNNQCELLSQLKGNLEEEN 1323
Cdd:PTZ00121 1841 MQLEEADAFEKHKFNKNNEN 1860
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
883-1343 |
3.01e-09 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 62.09 E-value: 3.01e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 883 LKELEKENKELVK----RATIDIKTLVTLREDLVSEKLKT---QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKL 955
Cdd:COG4717 48 LERLEKEADELFKpqgrKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 956 LESKLE-STLKKSLEIKEEKIAALEARLEEStnynQQLRQELKTVKKNYEALKQRQDEERmvqssppisgednkwERESQ 1034
Cdd:COG4717 128 LPLYQElEALEAELAELPERLEELEERLEEL----RELEEELEELEAELAELQEELEELL---------------EQLSL 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1035 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTvSLQEQNTTLQTQNAKLQVENSTLN 1114
Cdd:COG4717 189 ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEE-RLKEARLLLLIAAALLALLGLGGS 267
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1115 SQSTSLMNQNAQLLIQQSSLeneneSVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEH 1194
Cdd:COG4717 268 LLSLILTIAGVLFLVLGLLA-----LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLEL 342
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1195 RDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRlnhtYSQLLKETEVLQTDHKNLKSLL 1274
Cdd:COG4717 343 LDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEE----YQELKEELEELEEQLEELLGEL 418
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 208022632 1275 NN--SKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENR--HLLDQIQTLMLQNRTLLEQ 1343
Cdd:COG4717 419 EEllEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELAEE 491
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
611-1340 |
3.48e-09 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 62.24 E-value: 3.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 611 RQIKKELEHYKEKGERAEELENELHHLEKENELlqkkitnlkitCEKIEALEQENSELERenrkLKKTLDSFKNLTfQLE 690
Cdd:COG4913 228 DALVEHFDDLERAHEALEDAREQIELLEPIREL-----------AERYAAARERLAELEY----LRAALRLWFAQR-RLE 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 691 SLEKEnsqLDEENLELRRNVEslkcasmKMAQLQLENKELESEKEQLKKglELLKASFKKTERLEVsyqgldiENQRLQK 770
Cdd:COG4913 292 LLEAE---LEELRAELARLEA-------ELERLEARLDALREELDELEA--QIRGNGGDRLEQLER-------EIERLER 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 771 TLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK-RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQqaEIKD 849
Cdd:COG4913 353 ELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAaLLEALEEELEALEEALAEAEAALRDLRRELRELEA--EIAS 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 850 ttLEENNVKI-GNLEKENKTLSKEIGIYKESCVRLKEL-EKENKELVKRATIDiKTLVTLRED-LVSEKlktqqmnnDLE 926
Cdd:COG4913 431 --LERRKSNIpARLLALRDALAEALGLDEAELPFVGELiEVRPEEERWRGAIE-RVLGGFALTlLVPPE--------HYA 499
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 927 KLTHELEKIGLnKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAA-LEARLEESTNY-----NQQLRQELK--- 997
Cdd:COG4913 500 AALRWVNRLHL-RGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAwLEAELGRRFDYvcvdsPEELRRHPRait 578
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 998 ---TVKKNYEAL-KQRQDEERmvqsSPPISGEDNkweresqettRELLKVKDRLIevernnATLQAEKQALKTQLKQLET 1073
Cdd:COG4913 579 ragQVKGNGTRHeKDDRRRIR----SRYVLGFDN----------RAKLAALEAEL------AELEEELAEAEERLEALEA 638
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1074 QNNNLQAQILALQRQTVSLQEQNTTLQTQNAklqvenstlnsqstslmnqnaqllIQQssLENENESVIKEREDLKSLYD 1153
Cdd:COG4913 639 ELDALQERREALQRLAEYSWDEIDVASAERE------------------------IAE--LEAELERLDASSDDLAALEE 692
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1154 SLikdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQL--LKQKGQLEDLEKMLKVEQEKmllenKN 1231
Cdd:COG4913 693 QL----EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAedLARLELRALLEERFAAALGD-----AV 763
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1232 HETVAAEY-KKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKE----QYQQlDITSTKLN 1306
Cdd:COG4913 764 ERELRENLeERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEdglpEYEE-RFKELLNE 842
|
730 740 750
....*....|....*....|....*....|....
gi 208022632 1307 NQCELLSQLKGNLEEENRHLLDQIQTLmlqNRTL 1340
Cdd:COG4913 843 NSIEFVADLLSKLRRAIREIKERIDPL---NDSL 873
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
580-1244 |
3.62e-09 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 62.02 E-value: 3.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 580 ARVKDIEKENKILHESIKETSsKLSKIEFEKRQIKKELEHYK-----EKGERAEELENELHHLE--KENELLQKKITNLK 652
Cdd:COG5022 810 KEYRSYLACIIKLQKTIKREK-KLRETEEVEFSLKAEVLIQKfgrslKAKKRFSLLKKETIYLQsaQRVELAERQLQELK 888
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 653 ITCEKIEALEQENSELERENRKLKKTLDS--FKNLTFQLESLEKENSQLDEENLELrrnveslkcASMKMAQLQLENKEL 730
Cdd:COG5022 889 IDVKSISSLKLVNLELESEIIELKKSLSSdlIENLEFKTELIARLKKLLNNIDLEE---------GPSIEYVKLPELNKL 959
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 731 ESEKEQLKKglellkasfkkterlevsyqgldienqrLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRL 810
Cdd:COG5022 960 HEVESKLKE----------------------------TSEEYEDLLKKSTILVREGNKANSELKNFKKELAELSKQYGAL 1011
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKD----TTLEEN----NVKIGNLEKENKTLSK------EIGIY 876
Cdd:COG5022 1012 QESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKlkglLLLENNqlqaRYKALKLRRENSLLDDkqlyqlESTEN 1091
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 877 KESCVRLKELEKENKELVKRATIDIKTL-VTLREDLVSEKLK--------TQQMNNDLEKLTHELEKIG--LNKERLLHd 945
Cdd:COG5022 1092 LLKTINVKDLEVTNRNLVKPANVLQFIVaQMIKLNLLQEISKflsqlvntLEPVFQKLSVLQLELDGLFweANLEALPS- 1170
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 946 eqstddrYKLLESKLESTLKKSleikeekiAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQS------- 1018
Cdd:COG5022 1171 -------PPPFAALSEKRLYQS--------ALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISegwvpte 1235
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1019 -SPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQ---- 1093
Cdd:COG5022 1236 ySTSLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKsate 1315
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1094 -EQNTTLQtQNAKLQVENSTLNSQSTSLMnQNAQLLiqqsslenenESVIKEREDLKSLYDSL--IKDHEKLELLHERQA 1170
Cdd:COG5022 1316 vNYNSEEL-DDWCREFEISDVDEELEELI-QAVKVL----------QLLKDDLNKLDELLDACysLNPAEIQNLKSRYDP 1383
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 208022632 1171 SEYEsliskHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQlEDLEKMLKvEQEKMLLENKNHETVAAEYKKLCG 1244
Cdd:COG5022 1384 ADKE-----NNLPKEILKKIEALLIKQELQLSLEGKDETE-VHLSEIFS-EEKSLISLDRNSIYKEEVLSSLSA 1450
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
264-782 |
4.04e-09 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 61.68 E-value: 4.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 264 RQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDarSARMYRDELDALREKAVRVDKLESEVSRYKERLHD-IEFY 342
Cdd:pfam05557 1 RAELIESKARLSQLQNEKKQMELEHKRARIELEKKASA--LKRQLDRESDRNQELQKRIRLLEKREAEAEEALREqAELN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHEL----EKENLQLKAKLHDMEMER---DMDRKKIEELMEENMTL 415
Cdd:pfam05557 79 RLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELrrqiQRAELELQSTNSELEELQerlDLLKAKASEAEQLRQNL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 416 EMAQKQSMDESLH---LGWELEQISRTSELSEAPQKSLGhEVNELTS---------SRLLKLEMENQSLTKTVEELRTTV 483
Cdd:pfam05557 159 EKQQSSLAEAEQRikeLEFEIQSQEQDSEIVKNSKSELA-RIPELEKelerlrehnKHLNENIENKLLLKEEVEDLKRKL 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 484 DSVEGNASKILKMEKENQRLSKKV-----------------EILENEIVQEKQ--------------SLQNCQNLSKDLM 532
Cdd:pfam05557 238 EREEKYREEAATLELEKEKLEQELqswvklaqdtglnlrspEDLSRRIEQLQQreivlkeenssltsSARQLEKARRELE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 533 KEKAQLEKTIETL---RENSERQIKILEQENEHLNQTVSSLRQ-----RSQISAEARVKDIEKENKILHESIKETSSKLS 604
Cdd:pfam05557 318 QELAQYLKKIEDLnkkLKRHKALVRRLQRRVLLLTKERDGYRAilesyDKELTMSNYSPQLLERIEEAEDMTQKMQAHNE 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 605 KIEFEKRQIKKELEHYKekgERAEELENELHHLEKENELLQKKITNLKITC--EKIEALEQENSELERENRKLKKtldsf 682
Cdd:pfam05557 398 EMEAQLSVAEEELGGYK---QQAQTLERELQALRQQESLADPSYSKEEVDSlrRKLETLELERQRLREQKNELEM----- 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 683 knltfqleSLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLD 762
Cdd:pfam05557 470 --------ELERRCLQGDYDPKKTKVLHLSMNPAAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMN 541
|
570 580
....*....|....*....|.
gi 208022632 763 I-ENQRLQKTLENSNKKIQQL 782
Cdd:pfam05557 542 FkEVLDLRKELESAELKNQRL 562
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
577-816 |
5.19e-09 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 60.55 E-value: 5.19e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 577 SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELehykekgeraEELENELHHLEKENELLQKKITNLKitcE 656
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQL----------AALERRIAALARRIRALEQELAALE---A 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 657 KIEALEQENSELERENRKLKKTLDSfknltfQLESLEKENSQldeENLELRRNVESLKCASMKMAQLQLENKELESEKEQ 736
Cdd:COG4942 84 ELAELEKEIAELRAELEAQKEELAE------LLRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 737 LKKGLELLKAS----FKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQ 812
Cdd:COG4942 155 LRADLAELAALraelEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
|
....
gi 208022632 813 LEKE 816
Cdd:COG4942 235 EAAA 238
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
773-1377 |
7.21e-09 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 60.85 E-value: 7.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 773 ENSNKKIQQLESELQDLEMENQTLQKNLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRqqaeikdtTL 852
Cdd:PRK03918 189 ENIEELIKEKEKELEEVLREINEISSELPEL---REELEKLEKEVKELEELKEEIEELEKELESLEGSKR--------KL 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 853 EEnnvKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKratidiktLVTLREDLVSEKlktqqmnNDLEKLTHEL 932
Cdd:PRK03918 258 EE---KIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK--------LSEFYEEYLDEL-------REIEKRLSRL 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 933 EKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEkiaalearleestnynQQLRQELKTVKKNYEALKQRqde 1012
Cdd:PRK03918 320 EEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEER----------------HELYEEAKAKKEELERLKKR--- 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1013 ermvqssppisgednKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA--QILALQRQTV 1090
Cdd:PRK03918 381 ---------------LTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakGKCPVCGREL 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1091 SLQEQNTTLQTQNAKLqvenSTLNSQSTSLMNQNAQLLIQQSSLENEnesVIKERE--DLKSLYDSLIKDHEKLELLH-- 1166
Cdd:PRK03918 446 TEEHRKELLEEYTAEL----KRIEKELKEIEEKERKLRKELRELEKV---LKKESEliKLKELAEQLKELEEKLKKYNle 518
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1167 --ERQASEYESLISKHGTLKSAHKNLEvehRDLEdRYNQLLKQKGQLEdlEKMLKVEQEKMLLENKNHETVAAEYKKLCG 1244
Cdd:PRK03918 519 elEKKAEEYEKLKEKLIKLKGEIKSLK---KELE-KLEELKKKLAELE--KKLDELEEELAELLKELEELGFESVEELEE 592
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1245 ENDRLNHTYSQLLKetevlqtdhknLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEEN- 1323
Cdd:PRK03918 593 RLKELEPFYNEYLE-----------LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEy 661
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*..
gi 208022632 1324 ---RHLLDQIQTLMLQNRTLLEQNMESKDlfhveqrQYIDKLNELRRQKEKLEEKIM 1377
Cdd:PRK03918 662 eelREEYLELSRELAGLRAELEELEKRRE-------EIKKTLEKLKEELEEREKAKK 711
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
917-1147 |
1.16e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 59.39 E-value: 1.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 996
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 997 KTVKKNYEALKQRQdeERMVQSSPP---ISGEDnkweresqettreLLKVKDRLIEVERNNATLQAEKQALKTQLKQLET 1073
Cdd:COG4942 100 EAQKEELAELLRAL--YRLGRQPPLallLSPED-------------FLDAVRRLQYLKYLAPARREQAEELRADLAELAA 164
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 208022632 1074 QNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1147
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
796-1157 |
1.68e-08 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 59.93 E-value: 1.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 796 LQKNLEELKissKRlEQLEKENKSLEQ---ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Cdd:PRK11281 41 VQAQLDALN---KQ-KLLEAEDKLVQQdleQTLALLDKIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 873 IgIYKEScvrLKELEKE-NKELVKRATIDiKTLVTLREDLVSEK--------------LKTQQMNNDLEKLTHELEKIGL 937
Cdd:PRK11281 117 T-LSTLS---LRQLESRlAQTLDQLQNAQ-NDLAEYNSQLVSLQtqperaqaalyansQRLQQIRNLLKGGKVGGKALRP 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 938 NKERLLHDEQS-----TDDRYKLLE--SKLESTLKKSLEIKEEKIAALEAR---LEESTNyNQQLRQELKTVKknyEAlk 1007
Cdd:PRK11281 192 SQRVLLQAEQAllnaqNDLQRKSLEgnTQLQDLLQKQRDYLTARIQRLEHQlqlLQEAIN-SKRLTLSEKTVQ---EA-- 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1008 QRQDEERMVQSSPPISGEdnkweresQETTRELlkvKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILAL-- 1085
Cdd:PRK11281 266 QSQDEAARIQANPLVAQE--------LEINLQL---SQRLLKATEKLNTLTQQNLRVKNWLDRLTQSERNIKEQISVLkg 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1086 ----------QRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNA---QLLIQQSSLENENE-----SVIKERED 1147
Cdd:PRK11281 335 slllsrilyqQQQALPSADLIEGLADRIADLRLEQFEINQQRDALFQPDAyidKLEAGHKSEVTDEVrdallQLLDERRE 414
|
410
....*....|
gi 208022632 1148 lksLYDSLIK 1157
Cdd:PRK11281 415 ---LLDQLNK 421
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
990-1207 |
2.31e-08 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 58.24 E-value: 2.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 990 QQLRQELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKtqlK 1069
Cdd:COG4942 23 AEAEAELEQLQQEIAELEKELAALKKEEKA--LLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR---A 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1070 QLETQNNNLQAQILALQRQtvSLQEQNTTLQTQNAKLQVENST--LNSQSTSLMNQNAQLLIQQSSLENENESVIKERED 1147
Cdd:COG4942 98 ELEAQKEELAELLRALYRL--GRQPPLALLLSPEDFLDAVRRLqyLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1148 LKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQ 1207
Cdd:COG4942 176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
666-1180 |
3.83e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 58.24 E-value: 3.83e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 666 SELERENRKL-KKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL 744
Cdd:COG4717 49 ERLEKEADELfKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLL 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 745 KAsFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISS-KRLEQLEKENKSLEQE 823
Cdd:COG4717 129 PL-YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATeEELQDLAEELEELQQR 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEennvkignLEKENKTLSKEIGIYKESCVRLkELEKENKELVKRATIDIKT 903
Cdd:COG4717 208 LAELEEELEEAQEELEELEEELEQLENELE--------AAALEERLKEARLLLLIAAALL-ALLGLGGSLLSLILTIAGV 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESklesTLKKSLEIKEEKIAALEARLE 983
Cdd:COG4717 279 LFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPD----LSPEELLELLDRIEELQELLR 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 984 ESTNYNQQLR-QELKTVKKNYEALKQRQDEERMVQSSppisgednKWERESQETTRELLKVKDRLieverNNATLQAEKQ 1062
Cdd:COG4717 355 EAEELEEELQlEELEQEIAALLAEAGVEDEEELRAAL--------EQAEEYQELKEELEELEEQL-----EELLGELEEL 421
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1063 ALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTlnsqstslmnqnAQLLIQQSSLENENESVI 1142
Cdd:COG4717 422 LEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGEL------------AELLQELEELKAELRELA 489
|
490 500 510
....*....|....*....|....*....|....*...
gi 208022632 1143 KEREDLKSLYDSLikdHEKLELLHERQASEYESLISKH 1180
Cdd:COG4717 490 EEWAALKLALELL---EEAREEYREERLPPVLERASEY 524
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
241-570 |
4.20e-08 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 58.54 E-value: 4.20e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 241 KRTESRQH---LSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllsdarsarmYRDELDALRE 317
Cdd:TIGR02169 696 ELRRIENRldeLSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEN----------VKSELKELEA 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 318 kavRVDKLESEVSRYKERLHDIE--FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE----LEKENLQLKAKL 391
Cdd:TIGR02169 766 ---RIEELEEDLHKLEEALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLekeyLEKEIQELQEQR 842
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 392 HDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Cdd:TIGR02169 843 IDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 472 LTK---------TVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILE---NEIVQEKQSLQNCQNLSKD----LMKEK 535
Cdd:TIGR02169 923 KAKlealeeelsEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEpvnMLAIQEYEEVLKRLDELKEkrakLEEER 1002
|
330 340 350
....*....|....*....|....*....|....*..
gi 208022632 536 AQLEKTIETLrENSERQI--KILEQENEHLNQTVSSL 570
Cdd:TIGR02169 1003 KAILERIEEY-EKKKREVfmEAFEAINENFNEIFAEL 1038
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
725-1316 |
4.59e-08 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 58.37 E-value: 4.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELK 804
Cdd:PRK01156 159 LEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLK 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 805 ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEiKDTTLEENNV---------------KIGNLEKENKTL 869
Cdd:PRK01156 239 SALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEE-RHMKIINDPVyknrnyindyfkyknDIENKKQILSNI 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 870 SKEIGIYKESCVRLKELEKENKELVKRATiDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQST 949
Cdd:PRK01156 318 DAEINKYHAIIKKLSVLQKDYNDYIKKKS-RYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEI 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 950 DDRYKLLESKLESTL---KKSLEIKEEKIAALEARLEestnynqQLRQELKTVKKNYEALKQrqdeermvQSSPPISGE- 1025
Cdd:PRK01156 397 LKIQEIDPDAIKKELneiNVKLQDISSKVSSLNQRIR-------ALRENLDELSRNMEMLNG--------QSVCPVCGTt 461
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1026 --DNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNN-----------LQAQILALQRQTVSL 1092
Cdd:PRK01156 462 lgEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINksineynkiesARADLEDIKIKINEL 541
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1093 QEQNTTL-QTQNAKLQVENSTLNSQSTSLMNQNAQLliqqSSLENENesVIKEREDLKSLYDSLIKDHEKLELLHERQAS 1171
Cdd:PRK01156 542 KDKHDKYeEIKNRYKSLKLEDLDSKRTSWLNALAVI----SLIDIET--NRSRSNEIKKQLNDLESRLQEIEIGFPDDKS 615
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1172 EYESLISKhgtlksahknLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEkmllenknhetvaaEYKKLCGENDRLNH 1251
Cdd:PRK01156 616 YIDKSIRE----------IENEANNLNNKYNEIQENKILIEKLRGKIDNYKK--------------QIAEIDSIIPDLKE 671
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 208022632 1252 TYSQLLKetevLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLK 1316
Cdd:PRK01156 672 ITSRIND----IEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIK 732
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
575-831 |
6.24e-08 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 57.72 E-value: 6.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 575 QISAEARVKDIE---------KENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENElhhlekENELLQ 645
Cdd:PHA02562 146 QLSAPARRKLVEdlldisvlsEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGE------NIARKQ 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 646 KKITNLKITCEKIEA-LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCasmkMAQLQ 724
Cdd:PHA02562 220 NKYDELVEEAKTIKAeIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTC----TQQIS 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 725 LENKELESEKEQLK---KGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQknlE 801
Cdd:PHA02562 296 EGPDRITKIKDKLKelqHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQ---A 372
|
250 260 270
....*....|....*....|....*....|
gi 208022632 802 ELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Cdd:PHA02562 373 EFVDNAEELAKLQDELDKIVKTKSELVKEK 402
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
770-1201 |
7.97e-08 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 57.47 E-value: 7.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 770 KTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE--KENKRLRQQAEI 847
Cdd:COG4717 64 RKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPlyQELEALEAELAE 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 848 KDT---TLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKElvKRATIDIKTLVTLREDLVSEKLKTQQMNND 924
Cdd:COG4717 144 LPErleELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE--EELQDLAEELEELQQRLAELEEELEEAQEE 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 925 LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE----SKLESTLKKSLEIKEEKIAALEARLEESTNYNQQL-RQELKTV 999
Cdd:COG4717 222 LEELEEELEQLENELEAAALEERLKEARLLLLIaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLaREKASLG 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1000 KKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERnnatlQAEKQALKTQLKQLETQNNNLQ 1079
Cdd:COG4717 302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLR-----EAEELEEELQLEELEQEIAALL 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1080 A-----------QILALQRQTVSLQEQNTTLQTQ--NAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKERE 1146
Cdd:COG4717 377 AeagvedeeelrAALEQAEEYQELKEELEELEEQleELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELA 456
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 208022632 1147 DLKSLYDSLIKDHEKLELLHERQ--ASEYESLISKHGTLKSAHKNLEVEHRDLEDRY 1201
Cdd:COG4717 457 ELEAELEQLEEDGELAELLQELEelKAELRELAEEWAALKLALELLEEAREEYREER 513
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
261-974 |
1.05e-07 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 57.40 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 261 RRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENmnllsdarsarmyrDELDALREKAVRVDKLESEVSRYKErlhdie 340
Cdd:COG5022 857 AKKRFSLLKKETIYLQSAQRVELAERQLQELKIDV--------------KSISSLKLVNLELESEIIELKKSLS------ 916
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 341 fykarvEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKenLQLKAKLHDMEmerdmdrKKIEELMEEnmtLEMAQK 420
Cdd:COG5022 917 ------SDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVK--LPELNKLHEVE-------SKLKETSEE---YEDLLK 978
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 421 QSmdeslhlgweleqisrtselseapqkslghevnELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKEN 500
Cdd:COG5022 979 KS---------------------------------TILVREGNKANSELKNFKKELAELSKQYGALQESTKQLKELPVEV 1025
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 501 QRLSKKVEILeNEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRenserqikiLEQENEHLNQTVSSLRQRSQIsaea 580
Cdd:COG5022 1026 AELQSASKII-SSESTELSILKPLQKLKGLLLLENNQLQARYKALK---------LRRENSLLDDKQLYQLESTEN---- 1091
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 581 rvkdieKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKitCEKIEA 660
Cdd:COG5022 1092 ------LLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQLELD--GLFWEA 1163
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 661 LEQENSELERENRKLKKTLdsfknltFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG 740
Cdd:COG5022 1164 NLEALPSPPPFAALSEKRL-------YQSALYDEKSKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVPTEY 1236
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 741 LELLKAS-----FKKTERLEVSYQGLDIENQrLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEK 815
Cdd:COG5022 1237 STSLKGFnnlnkKFDTPASMSNEKLLSLLNS-IDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKASSLRWKSATE 1315
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 816 ENKSLEQE------------TSQLEKDK---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEigiykesc 880
Cdd:COG5022 1316 VNYNSEELddwcrefeisdvDEELEELIqavKVLQLLKDDLNKLDELLDACYSLNPAEIQNLKSRYDPADKE-------- 1387
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 881 vrlKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNndleklthelekiglNKERLLHDEQSTDDRYKLLESKL 960
Cdd:COG5022 1388 ---NNLPKEILKKIEALLIKQELQLSLEGKDETEVHLSEIFS---------------EEKSLISLDRNSIYKEEVLSSLS 1449
|
730
....*....|....
gi 208022632 961 ESTLKKSLEIKEEK 974
Cdd:COG5022 1450 ALLTKEKIALLDRK 1463
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
252-822 |
1.64e-07 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 56.46 E-value: 1.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllSDARSARMYRDELDALREkavRVDKLESEVSR 331
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLER---ELEERERRRAR 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 332 YKERLHDIEFykarveELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLhdmemerdmdRKKIEELMEE 411
Cdd:COG4913 364 LEALLAALGL------PLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL----------RRELRELEAE 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 412 NMTLEmAQKQSMDESLHlgwEL-EQISRTSELSEAPQKSLGH--EVNELTSS------RLLKlemeNQSLTKTVEE---- 478
Cdd:COG4913 428 IASLE-RRKSNIPARLL---ALrDALAEALGLDEAELPFVGEliEVRPEEERwrgaieRVLG----GFALTLLVPPehya 499
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 479 ----------LRTTVDS--VEGNASKILKMEKENQRLSKKVEILENEIvqekqslqncQNLSKDLMKEKAQLEK--TIET 544
Cdd:COG4913 500 aalrwvnrlhLRGRLVYerVRTGLPDPERPRLDPDSLAGKLDFKPHPF----------RAWLEAELGRRFDYVCvdSPEE 569
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 545 LRENS-----ERQIKILEQENEHlnQTVSSLRQRSQI--SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKEL 617
Cdd:COG4913 570 LRRHPraitrAGQVKGNGTRHEK--DDRRRIRSRYVLgfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERR 647
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 618 EHY-------------KEKGERAEELENELHHLEKEN---ELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDS 681
Cdd:COG4913 648 EALqrlaeyswdeidvASAEREIAELEAELERLDASSddlAALEEQLEELE---AELEELEEELDELKGEIGRLEKELEQ 724
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 682 F----KNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM-AQLQLENKELESEKEQLKKGLELLKASFKKTERLEV 756
Cdd:COG4913 725 AeeelDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELrENLEERIDALRARLNRAEEELERAMRAFNREWPAET 804
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 208022632 757 SYQGLDIEN----QRLQKTLENSN-----KKIQQL--ESELQDLEMENQTLQKNLEELKisskrlEQLEKENKSLEQ 822
Cdd:COG4913 805 ADLDADLESlpeyLALLDRLEEDGlpeyeERFKELlnENSIEFVADLLSKLRRAIREIK------ERIDPLNDSLKR 875
|
|
| Crescentin |
pfam19220 |
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ... |
508-872 |
1.90e-07 |
|
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.
Pssm-ID: 437057 [Multi-domain] Cd Length: 401 Bit Score: 55.46 E-value: 1.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 508 EILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK---ILEQE---NEHLNQTVSSLRQRSQiSAEAR 581
Cdd:pfam19220 6 ELLRVRLGEMADRLEDLRSLKADFSQLIEPIEAILRELPQAKSRLLEleaLLAQEraaYGKLRRELAGLTRRLS-AAEGE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 582 VKDIEKENKILHESIKETSSKLSKIEFEKRQ-------IKKELEHykeKGERAEELENELHHLEKENELLQKKITNLKit 654
Cdd:pfam19220 85 LEELVARLAKLEAALREAEAAKEELRIELRDktaqaeaLERQLAA---ETEQNRALEEENKALREEAQAAEKALQRAE-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 655 cEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESlKCASMK------MAQLQLENK 728
Cdd:pfam19220 160 -GELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARLRALEG-QLAAEQaereraEAQLEEAVE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 729 ELESEKEQLKKGLELLKASFKKTERLevsyqgldienqrlqktlensnkkIQQLESELQDLEMENQTLQKNLEELKIS-- 806
Cdd:pfam19220 238 AHRAERASLRMKLEALTARAAATEQL------------------------LAEARNQLRDRDEAIRAAERRLKEASIErd 293
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 208022632 807 --SKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE 872
Cdd:pfam19220 294 tlERRLAGLEADLERRTQQFQEMQRARAELEERAEMLTKALAAKDAALERAEERIASLSDRIAELTKR 361
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
345-652 |
2.43e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 55.90 E-value: 2.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 345 RVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdMEMERDMDRKKIEELMEENMTLEMAQkqsmd 424
Cdd:pfam17380 300 RLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMA-----MERERELERIRQEERKRELERIRQEE----- 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 425 eslhLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLK-LEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRl 503
Cdd:pfam17380 370 ----IAMEISRMRELERLQMERQQKNERVRQELEAARKVKiLEEERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEER- 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 504 SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHlnqtvsslRQRSQISAEARVK 583
Cdd:pfam17380 445 AREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEE--------RKQAMIEEERKRK 516
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 208022632 584 DIEKENKILHESIKETSSKlsKIEFEKRQIKKELEHYK---EKGERAEELENELHHLEKENELLQKKITNLK 652
Cdd:pfam17380 517 LLEKEMEERQKAIYEEERR--REAEEERRKQQEMEERRriqEQMRKATEERSRLEAMEREREMMRQIVESEK 586
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
573-861 |
2.59e-07 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 56.07 E-value: 2.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 573 RSQISAEARVKDIEKENKILHESIKETSSKLSKIEfekrQIKKELehykekgeraEELENELHHLEKENELLQKKITNLK 652
Cdd:PRK11281 42 QAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKID----RQKEET----------EQLKQQLAQAPAKLRQAQAELEALK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 653 ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLekeNSQLDEENLELRRNVESLKCASMKMAQLqleNKELES 732
Cdd:PRK11281 108 DDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEY---NSQLVSLQTQPERAQAALYANSQRLQQI---RNLLKG 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 733 EKEqlkkGLELLKASFKktERLEVSYQGLDIENQRLQKTLENsNKKIQQLESELQDLEMENQT-LQKNLEELK--ISSKR 809
Cdd:PRK11281 182 GKV----GGKALRPSQR--VLLQAEQALLNAQNDLQRKSLEG-NTQLQDLLQKQRDYLTARIQrLEHQLQLLQeaINSKR 254
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 810 LEQLEKENKSLE--QETSQLEKD---KKQLEKeNKRLRQ---QAEIKDTTLEENNVKIGN 861
Cdd:PRK11281 255 LTLSEKTVQEAQsqDEAARIQANplvAQELEI-NLQLSQrllKATEKLNTLTQQNLRVKN 313
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
726-893 |
2.77e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.77 E-value: 2.77e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 726 ENKELESEKEQLKKGLELLKASFKKTERLEVSYQG----LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE 801
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKqlaaLERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 802 ELK-----------------------------ISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTL 852
Cdd:COG4942 101 AQKeelaellralyrlgrqpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 208022632 853 EENNVKIGNLEKE----NKTLSKEIGIYKESCVRLKELEKENKEL 893
Cdd:COG4942 181 AELEEERAALEALkaerQKLLARLEKELAELAAELAELQQEAEEL 225
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
252-1368 |
3.68e-07 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 55.83 E-value: 3.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKrlqqENMNLLSDARSARMYRDELDALREK----AVRVDK--- 324
Cdd:TIGR01612 1112 EINKIKDDIKNLDQKIDHHIKALEEIKKKSENYIDEIK----AQINDLEDVADKAISNDDPEEIEKKieniVTKIDKkkn 1187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 325 LESEVSRYKERLHDIEFYKARVEELKEDNQVLLET--KTMLEDQLEGTRARSDKLHELEK-----ENLQLKAKLHDMEME 397
Cdd:TIGR01612 1188 IYDEIKKLLNEIAEIEKDKTSLEEVKGINLSYGKNlgKLFLEKIDEEKKKSEHMIKAMEAyiedlDEIKEKSPEIENEMG 1267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 398 RDMDRKKIEELM-------EENMTLEMAQKQSM----DESLHLGWELEQISRTSELSEAPQKSL------GHEVNELTSS 460
Cdd:TIGR01612 1268 IEMDIKAEMETFnishdddKDHHIISKKHDENIsdirEKSLKIIEDFSEESDINDIKKELQKNLldaqkhNSDINLYLNE 1347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 461 -----RLLKLEM------ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRL----SKKVEILENEIVQEkqSLQNCQ 525
Cdd:TIGR01612 1348 ianiyNILKLNKikkiidEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINLeeckSKIESTLDDKDIDE--CIKKIK 1425
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 526 NLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRqrsqISAEARVKDIEKENKILHESIKETSSKLSK 605
Cdd:TIGR01612 1426 ELKNHILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILK----IKKDNATNDHDFNINELKEHIDKSKGCKDE 1501
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 606 IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKtldsFKNL 685
Cdd:TIGR01612 1502 ADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKE----IKKE 1577
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 686 TFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKElesekeqlkkglellkaSFKKTERLEVSYQGLDIEN 765
Cdd:TIGR01612 1578 KFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKISDIKKKIND-----------------CLKETESIEKKISSFSIDS 1640
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 766 QrlqktlensnkkiqqlESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKenkrlrqqa 845
Cdd:TIGR01612 1641 Q----------------DTELKENGDNLNSLQEFLESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQHKK--------- 1695
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 846 eikdttleenNVKIGNLEKenktlskeigiykescvrLKELEKENKELVKRATIDIKTLVtlredlvsEKLKTQQMNNDL 925
Cdd:TIGR01612 1696 ----------NYEIGIIEK------------------IKEIAIANKEEIESIKELIEPTI--------ENLISSFNTNDL 1739
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 926 EKLTHElEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSL---EIKEEKIAA---LEARLEESTNYNQQLRQ-ELKT 998
Cdd:TIGR01612 1740 EGIDPN-EKLEEYNTEIGDIYEEFIELYNIIAGCLETVSKEPItydEIKNTRINAqneFLKIIEIEKKSKSYLDDiEAKE 1818
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 999 VKKNYEALKQRQDeermvQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL 1078
Cdd:TIGR01612 1819 FDRIINHFKKKLD-----HVNDKFTKEYSKINEGFDDISKSIENVKNSTDENLLFDILNKTKDAYAGIIGKKYYSYKDEA 1893
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1079 QAQILALQRQTVSLqeqNTTLQTQNAKLQVENSTLNSQStSLMNQNAQLLIQQSSLENENESVIKEREDlkslYDSLIKD 1158
Cdd:TIGR01612 1894 EKIFINISKLANSI---NIQIQNNSGIDLFDNINIAILS-SLDSEKEDTLKFIPSPEKEPEIYTKIRDS----YDTLLDI 1965
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1159 HEKLELLHERqasEYESLiskhgtlksahkNLEVEHRDLEDRYNQLLKQKGQLEDlekmLKVEQEKMLlenknhetvaAE 1238
Cdd:TIGR01612 1966 FKKSQDLHKK---EQDTL------------NIIFENQQLYEKIQASNELKDTLSD----LKYKKEKIL----------ND 2016
|
1050 1060 1070 1080 1090 1100 1110 1120
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1239 YKKLCGENDRLNHTYSQLLKETEVLQTDHKN-LKSLLNNSKLEQTRLEAEFS-KLKEQYQQLDITST-KLNNQCELLSQL 1315
Cdd:TIGR01612 2017 VKLLLHKFDELNKLSCDSQNYDTILELSKQDkIKEKIDNYEKEKEKFGIDFDvKAMEEKFDNDIKDIeKFENNYKHSEKD 2096
|
1130 1140 1150 1160 1170
....*....|....*....|....*....|....*....|....*....|....*
gi 208022632 1316 KGNLEEENRHLLDQIQTLmlqNRTLLEQNMESKDLFH--VEQRQYIDKLNELRRQ 1368
Cdd:TIGR01612 2097 NHDFSEEKDNIIQSKKKL---KELTEAFNTEIKIIEDkiIEKNDLIDKLIEMRKE 2148
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
775-1029 |
4.14e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 54.38 E-value: 4.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 775 SNKKIQQLESELQDLEmenqtlqknlEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEE 854
Cdd:COG4942 18 QADAAAEAEAELEQLQ----------QEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 855 NNVKIGNLEKENKTLSKEigiYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLvseKLKTQQMNNDLEKLTHELEK 934
Cdd:COG4942 88 LEKEIAELRAELEAQKEE---LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL---KYLAPARREQAEELRADLAE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 935 IGLNKERLLHDEQSTDDRYKLLESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEER 1014
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAA-LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
|
250
....*....|....*
gi 208022632 1015 MVQSSPPISGEDNKW 1029
Cdd:COG4942 241 ERTPAAGFAALKGKL 255
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
287-888 |
4.15e-07 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 55.29 E-value: 4.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 287 ELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYkerlhdiefykarVEELKEDNQVLLETKTMLEDQ 366
Cdd:PRK01156 150 QRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKLKSS-------------NLELENIKKQIADDEKSHSIT 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 367 LEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQisRTSELSEAP 446
Cdd:PRK01156 217 LKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSMELEKNNYYK-----ELEE--RHMKIINDP 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 447 QKSLGHEVNELtssrlLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKE-NQRLSKKVEIleNEIVQEKQSLQNCQ 525
Cdd:PRK01156 290 VYKNRNYINDY-----FKYKNDIENKKQILSNIDAEINKYHAIIKKLSVLQKDyNDYIKKKSRY--DDLNNQILELEGYE 362
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 526 NLSKDLMKEKAQLEKTIETLRENSERqikileqenehLNQTVSSLRQRSQISAEARVKDIEKENKilheSIKETSSKLSK 605
Cdd:PRK01156 363 MDYNSYLKSIESLKKKIEEYSKNIER-----------MSAFISEILKIQEIDPDAIKKELNEINV----KLQDISSKVSS 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 606 IEFEKRQIKKELEHYKEK-----------------------------GERAEELENELHHLEKENELLQKKITNLK---- 652
Cdd:PRK01156 428 LNQRIRALRENLDELSRNmemlngqsvcpvcgttlgeeksnhiinhyNEKKSRLEEKIREIEIEVKDIDEKIVDLKkrke 507
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 653 -ITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE-LRRNVESLKCASMKMAQLQLENkeL 730
Cdd:PRK01156 508 yLESEEINKSINEYNKIESARADLEDIKIKINELKDKHDKYEEIKNRYKSLKLEdLDSKRTSWLNALAVISLIDIET--N 585
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 731 ESEKEQLKKglellkasfkKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRL 810
Cdd:PRK01156 586 RSRSNEIKK----------QLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNY 655
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 208022632 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEK 888
Cdd:PRK01156 656 KKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKKIKK 733
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
824-1213 |
4.21e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.46 E-value: 4.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKEnktlskeigiyKESCVRLKELEKENKELvkRATIDIKT 903
Cdd:TIGR02169 165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-----------REKAERYQALLKEKREY--EGYELLKE 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 904 LVTLREDLvseklktQQMNNDLEKLTHELEKIglnKERLlhdeQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLE 983
Cdd:TIGR02169 232 KEALERQK-------EAIERQLASLEEELEKL---TEEI----SELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIG 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 984 EstnynqqLRQELKTVKKNYEALKQRQDEErmvqssppisgednkwERESQETTRELLKVKDRLIEVERNNATLQAEKQA 1063
Cdd:TIGR02169 298 E-------LEAEIASLERSIAEKERELEDA----------------EERLAKLEAEIDKLLAEIEELEREIEEERKRRDK 354
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1064 LKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIK 1143
Cdd:TIGR02169 355 LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA 434
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1144 EREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLED 1213
Cdd:TIGR02169 435 KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEE 504
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
762-897 |
4.28e-07 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 54.86 E-value: 4.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 762 DIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQET-SQLEKDKK--QLEKEN 838
Cdd:COG2433 398 EREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKD---ERIERLERELSEARSEErREIRKDREisRLDREI 474
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 208022632 839 KRLRQQAEIKDTTLEENNVKignLEKENKTLSKEIgiyKESCVRLKELEKENKELVKRA 897
Cdd:COG2433 475 ERLERELEEERERIEELKRK---LERLKELWKLEH---SGELVPVKVVEKFTKEAIRRL 527
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
559-914 |
4.52e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 55.13 E-value: 4.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 559 ENEHLNQTVSSLRQRSQISAEarvKDIEKENKILHESIKETSSKLSKiEFEKRQIKKELEH------------YKEKGER 626
Cdd:pfam17380 267 ENEFLNQLLHIVQHQKAVSER---QQQEKFEKMEQERLRQEKEEKAR-EVERRRKLEEAEKarqaemdrqaaiYAEQERM 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 627 AEELENELHHL---EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEEN 703
Cdd:pfam17380 343 AMERERELERIrqeERKRELERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEM 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 704 LELRRNVESLKcasmkmaqlQLENKELESEKEQlkkglELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLE 783
Cdd:pfam17380 423 EQIRAEQEEAR---------QREVRRLEEERAR-----EMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKR 488
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 784 SElqdlEMENQTLQKNLEElkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLE 863
Cdd:pfam17380 489 AE----EQRRKILEKELEE-----RKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMR 559
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 208022632 864 KENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSE 914
Cdd:pfam17380 560 KATEERSRLEAMEREREMMRQIVESEKARAEYEATTPITTIKPIYRPRISE 610
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
243-673 |
6.76e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 54.39 E-value: 6.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 243 TESRQHLSVELADAKAKIRRLRQELE--EKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsARMYRDELDALREKAV 320
Cdd:COG4717 94 QEELEELEEELEELEAELEELREELEklEKLLQLLPLYQELEALEAELAELPER----------LEELEERLEELRELEE 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 321 RVDKLESEVSRYKERLHDIEFY-----KARVEELKEDNQVLLETKTMLEDQLEGTRArsdklhelEKENLQLKAKLHDME 395
Cdd:COG4717 164 ELEELEAELAELQEELEELLEQlslatEEELQDLAEELEELQQRLAELEEELEEAQE--------ELEELEEELEQLENE 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 396 MERDMDRKKIEELMEENM------TLEMAQKQSMDESLHLG----WELEQISRTSELSEAPQKSLGHEVNELTSSRLLKl 465
Cdd:COG4717 236 LEAAALEERLKEARLLLLiaaallALLGLGGSLLSLILTIAgvlfLVLGLLALLFLLLAREKASLGKEAEELQALPALE- 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 466 EMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIvQEKQSLQNCQNLskdLMKEKAQLEKTIETL 545
Cdd:COG4717 315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL-QLEELEQEIAAL---LAEAGVEDEEELRAA 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 546 RENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYkEKGE 625
Cdd:COG4717 391 LEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQL-EEDG 469
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 208022632 626 RAEELENELHHLEKENELLQKKITNLKITcekIEALEQENSELERENR 673
Cdd:COG4717 470 ELAELLQELEELKAELRELAEEWAALKLA---LELLEEAREEYREERL 514
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
183-677 |
7.68e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.59 E-value: 7.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 183 QEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELAdAKAKIRR 262
Cdd:TIGR00618 385 QQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKL-EKIHLQE 463
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 263 LRQELEEKTEQLLD----CKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAV---RVDKLESEVSRYKER 335
Cdd:TIGR00618 464 SAQSLKEREQQLQTkeqiHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPltrRMQRGEQTYAQLETS 543
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 336 LHDIE-----------FYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLhdMEMERDMDRKK 404
Cdd:TIGR00618 544 EEDVYhqltserkqraSLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDML--ACEQHALLRKL 621
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 405 IEELMEENMTLEMAQKQSMDeslhlgwELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD 484
Cdd:TIGR00618 622 QPEQDLQDVRLHLQQCSQEL-------ALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTY 694
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 485 SVEGNASKILKMEKENQRLsKKVEILENEIVQEKQSLQncqnlsKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLN 564
Cdd:TIGR00618 695 WKEMLAQCQTLLRELETHI-EEYDREFNEIENASSSLG------SDLAAREDALNQSLKELMHQARTVLKARTEAHFNNN 767
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 565 QTVSSLRQRSQISAEArVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKgeRAEELENELHHLEKENELL 644
Cdd:TIGR00618 768 EEVTAALQTGAELSHL-AAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCET--LVQEEEQFLSRLEEKSATL 844
|
490 500 510
....*....|....*....|....*....|...
gi 208022632 645 QKKITNLKITCEKIEALEQENSELERENRKLKK 677
Cdd:TIGR00618 845 GEITHQLLKYEECSKQLAQLTQEQAKIIQLSDK 877
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
746-987 |
8.11e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.61 E-value: 8.11e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 746 ASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETS 825
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 826 QLEKDKKQLEKE-NKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSkeigiykescvRLKELEKENKELVKRATIDIKTL 904
Cdd:COG4942 94 ELRAELEAQKEElAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQ-----------YLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLhdeQSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEE 984
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLL---ARLEKELAELAAELA-ELQQEAEELEALIARLEAEAAA 238
|
...
gi 208022632 985 STN 987
Cdd:COG4942 239 AAE 241
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
550-903 |
1.43e-06 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 53.51 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 550 ERQIKILEQENEHLNQTVSSLRQrsQISAEARVKDIEKEN--KILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERA 627
Cdd:PTZ00108 998 EYLLGKLERELARLSNKVRFIKH--VINGELVITNAKKKDlvKELKKLGYVRFKDIIKKKSEKITAEEEEGAEEDDEADD 1075
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 628 EELENELHHLEKENELLQKKITNLkiTCEKIEALEQENSELERENRKLKKTldSFKNLtfQLESLEKENSQLDEEnlELR 707
Cdd:PTZ00108 1076 EDDEEELGAAVSYDYLLSMPIWSL--TKEKVEKLNAELEKKEKELEKLKNT--TPKDM--WLEDLDKFEEALEEQ--EEV 1147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 708 RNVESLKCASMKMAQLQlenKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQ 787
Cdd:PTZ00108 1148 EEKEIAKEQRLKSKTKG---KASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSD 1224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 788 DLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:PTZ00108 1225 QEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSS 1304
|
330 340 350
....*....|....*....|....*....|....*.
gi 208022632 868 TLSKEIGIYKEScvrlKELEKENKELVKRATIDIKT 903
Cdd:PTZ00108 1305 PTKKKVKKRLEG----SLAALKKKKKSEKKTARKKK 1336
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
577-695 |
1.58e-06 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 52.86 E-value: 1.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 577 SAEARVKDIEKE-NKILHESIKETSSKLSKIEFEKRQ--IKKELEHYKEKGERAEELEnelhhlEKENELLQKKiTNLKi 653
Cdd:PRK12704 28 IAEAKIKEAEEEaKRILEEAKKEAEAIKKEALLEAKEeiHKLRNEFEKELRERRNELQ------KLEKRLLQKE-ENLD- 99
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 208022632 654 tcEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Cdd:PRK12704 100 --RKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEE 139
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
505-858 |
2.05e-06 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 52.77 E-value: 2.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 505 KKVEILENEIVQEKQS-LQNCQNLSKDLMKEKAQLEKTIETLRENSER--------QIKILEQENEhlnqtVSSLRQRSQ 575
Cdd:pfam05622 30 KNSLQQENKKLQERLDqLESGDDSGTPGGKKYLLLQKQLEQLQEENFRletarddyRIKCEELEKE-----VLELQHRNE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 576 --ISAEARVKDIEKENKILhesiKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENE-----LHHLEKENELlqKKI 648
Cdd:pfam05622 105 elTSLAEEAQALKDEMDIL----RESSDKVKKLEATVETYKKKLEDLGDLRRQVKLLEERnaeymQRTLQLEEEL--KKA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 649 TNLKITCEKIEALEQE-NSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEN 727
Cdd:pfam05622 179 NALRGQLETYKRQVQElHGKLSEESKKADKLEFEYKKLEEKLEALQKEKERLIIERDTLRETNEELRCAQLQQAELSQAD 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 728 KELESEKEQLKK-GLELLKASFKKT-ERLEVSYQGLDI-----ENQR---LQKTLENSNKKIQQLESEL-----QDLEME 792
Cdd:pfam05622 259 ALLSPSSDPGDNlAAEIMPAEIREKlIRLQHENKMLRLgqegsYRERlteLQQLLEDANRRKNELETQNrlanqRILELQ 338
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 208022632 793 NQT--LQKNLEEL----KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVK 858
Cdd:pfam05622 339 QQVeeLQKALQEQgskaEDSSLLKQKLEEHLEKLHEAQSELQKKKEQIEELEPKQDSNLAQKIDELQEALRK 410
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
247-850 |
3.38e-06 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 52.53 E-value: 3.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 247 QHLSVELadaKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA-RMYRDELDALREKAVRVDKL 325
Cdd:pfam12128 261 SHLHFGY---KSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAvAKDRSELEALEDQHGAFLDA 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 326 ESEvsRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDklhelekenLQLKAKLHDMEMERDMDRKKI 405
Cdd:pfam12128 338 DIE--TAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK---------EQNNRDIAGIKDKLAKIREAR 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 406 EELMEENMTLEMAQKQSMDESLHLGweLEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMEN--QSLTKTVEELRTTV 483
Cdd:pfam12128 407 DRQLAVAEDDLQALESELREQLEAG--KLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENfdERIERAREEQEAAN 484
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 484 DSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQN------------LSKDLMKEKAQLEKTIET------- 544
Cdd:pfam12128 485 AEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELqlfpqagtllhfLRKEAPDWEQSIGKVISPellhrtd 564
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 545 ----LRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHY 620
Cdd:pfam12128 565 ldpeVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFA 644
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 621 KEKGERAEElenELHHLEKENELLQKKITnlKITCEKIEALEQENSELERENRKLKKTLDSFknltfqLESLEKENSQLD 700
Cdd:pfam12128 645 RTALKNARL---DLRRLFDEKQSEKDKKN--KALAERKDSANERLNSLEAQLKQLDKKHQAW------LEEQKEQKREAR 713
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 701 EENLELRRNVESLKCASM----------------KMAQLQLENK--------------ELESEKEQLKKGLELLKASFKK 750
Cdd:pfam12128 714 TEKQAYWQVVEGALDAQLallkaaiaarrsgakaELKALETWYKrdlaslgvdpdviaKLKREIRTLERKIERIAVRRQE 793
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 751 TERLEVSYQG-LDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQL- 827
Cdd:pfam12128 794 VLRYFDWYQEtWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEmERKASEKQQVRLSENLRGLRCEMSKLa 873
|
650 660
....*....|....*....|....*...
gi 208022632 828 ----EKDKKQLEKE-NKRLRQQAEIKDT 850
Cdd:pfam12128 874 tlkeDANSEQAQGSiGERLAQLEDLKLK 901
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
762-998 |
3.97e-06 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 51.85 E-value: 3.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 762 DIENQRLQKTLENS---NKKIQQLESELQDLEMENQTLQ----KNLEEL-KISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:PRK05771 39 ELSNERLRKLRSLLtklSEALDKLRSYLPKLNPLREEKKkvsvKSLEELiKDVEEELEKIEKEIKELEEEISELENEIKE 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 834 LEKENKRLRQqaeikdttLEENNVKIGNLeKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT---LVTLRED 910
Cdd:PRK05771 119 LEQEIERLEP--------WGNFDLDLSLL-LGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDKGYVyvvVVVLKEL 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 911 L--VSEKLKtqqmNNDLEKLthELEKIGLNKERLlhdeQSTDDRYKLLESKLEST---LKKSLEIKEEKIAALEARLEES 985
Cdd:PRK05771 190 SdeVEEELK----KLGFERL--ELEEEGTPSELI----REIKEELEEIEKERESLleeLKELAKKYLEELLALYEYLEIE 259
|
250
....*....|...
gi 208022632 986 TNYNQQLRQELKT 998
Cdd:PRK05771 260 LERAEALSKFLKT 272
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
671-1378 |
4.29e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 51.97 E-value: 4.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 671 ENRKLKKTLDSFKNLTFQLESLEK-------ENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKK---G 740
Cdd:TIGR00606 167 EGKALKQKFDEIFSATRYIKALETlrqvrqtQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSyenE 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 741 LELLKASFKKTERLEVSYQGLDIENQRLQKT---LENSNKKIQQL--------ESELQDLEMENQ-TLQKNLEELKISSK 808
Cdd:TIGR00606 247 LDPLKNRLKEIEHNLSKIMKLDNEIKALKSRkkqMEKDNSELELKmekvfqgtDEQLNDLYHNHQrTVREKERELVDCQR 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgNLEKENKTLSKEIGIYKESCVRLKELEK 888
Cdd:TIGR00606 327 ELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRL-ELDGFERGPFSERQIKNFHTLVIERQED 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 889 ENKELVKRATIDIKTLVTLREDL----VSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLE------- 957
Cdd:TIGR00606 406 EAKTAAQLCADLQSKERLKQEQAdeirDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQelrkaer 485
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 958 --------SKLESTLKKSLEIKEEK------IAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPIS 1023
Cdd:TIGR00606 486 elskaeknSLTETLKKEVKSLQNEKadldrkLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSL 565
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1024 GEDNKWERESQET----TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL------ALQRQTVSLQ 1093
Cdd:TIGR00606 566 LGYFPNKKQLEDWlhskSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFdvcgsqDEESDLERLK 645
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1094 EQNTTLQTQNAKLQVENSTLNSQSTSLMNQN--------------AQLLIQQSSLENENESVIKEREDLKSLYDSLIKDH 1159
Cdd:TIGR00606 646 EEIEKSSKQRAMLAGATAVYSQFITQLTDENqsccpvcqrvfqteAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRR 725
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1160 EKLELLHERQASEYESLISKHGTLKSAHKNLeveHRDLEDRYNQLLKQKGQL------EDLEKMLKVEQEKMLLENKNHE 1233
Cdd:TIGR00606 726 DEMLGLAPGRQSIIDLKEKEIPELRNKLQKV---NRDIQRLKNDIEEQETLLgtimpeEESAKVCLTDVTIMERFQMELK 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1234 TVAAEYKKLCGENDR--LNHTYSQLLKETEVLQTDHKNLKSLLN-NSKLEQTRleaefsklKEQYQQLDITSTKLNNQCE 1310
Cdd:TIGR00606 803 DVERKIAQQAAKLQGsdLDRTVQQVNQEKQEKQHELDTVVSKIElNRKLIQDQ--------QEQIQHLKSKTNELKSEKL 874
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 208022632 1311 LLS---QLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMD 1378
Cdd:TIGR00606 875 QIGtnlQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVND 945
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
253-714 |
5.35e-06 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 51.44 E-value: 5.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 253 LADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAvrvDKLESEVSRY 332
Cdd:PRK01156 185 IDYLEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMK---NRYESEIKTA 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 333 KERLHDIEFYKARVEELKEDNQVLLETKTM------------------LEDQLEGTRARSDKLHELEKENLQLKAKLHD- 393
Cdd:PRK01156 262 ESDLSMELEKNNYYKELEERHMKIINDPVYknrnyindyfkykndienKKQILSNIDAEINKYHAIIKKLSVLQKDYNDy 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 394 MEMERDMD--RKKIEELMEENM-------TLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSrLLK 464
Cdd:PRK01156 342 IKKKSRYDdlNNQILELEGYEMdynsylkSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVK-LQD 420
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 465 LEMENQSLTKTVEELRTTVDSVEGNAS-----------------------------KILKMEKENQRLSKKVEILENEIV 515
Cdd:PRK01156 421 ISSKVSSLNQRIRALRENLDELSRNMEmlngqsvcpvcgttlgeeksnhiinhyneKKSRLEEKIREIEIEVKDIDEKIV 500
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 516 QEK-----------QSLQNCQNLSKDLMKEKAQLEKTIETLRENSER-----------QIKILEQENEHLNQTVSslrQR 573
Cdd:PRK01156 501 DLKkrkeyleseeiNKSINEYNKIESARADLEDIKIKINELKDKHDKyeeiknrykslKLEDLDSKRTSWLNALA---VI 577
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 574 SQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PRK01156 578 SLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKK 657
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 208022632 654 TCEKIEALEQENSEL-------ERENRKLKKTLDSFKNLTFQLESLEK----ENSQLDEENLELRRNVESLK 714
Cdd:PRK01156 658 QIAEIDSIIPDLKEItsrindiEDNLKKSRKALDDAKANRARLESTIEilrtRINELSDRINDINETLESMK 729
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
957-1298 |
5.62e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 5.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 957 ESKLESTLKKsLEIKEEKIAALEARLEESTNYNQQLRQElKTVKKNYEALKQRqdeermvqssppisgednKWERESQET 1036
Cdd:TIGR02169 169 DRKKEKALEE-LEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKE------------------KREYEGYEL 228
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1037 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSL-QEQNTTLQTQNAKLQVENSTL-- 1113
Cdd:TIGR02169 229 LKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLer 308
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1114 -----NSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHK 1188
Cdd:TIGR02169 309 siaekERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1189 NLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMlleNKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHK 1268
Cdd:TIGR02169 389 DYREKLEKLKREINELKRELDRLQEELQRLSEELADL---NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLS 465
|
330 340 350
....*....|....*....|....*....|
gi 208022632 1269 NLKSLLNNSKLEQTRLEAEFSKLKEQYQQL 1298
Cdd:TIGR02169 466 KYEQELYDLKEEYDRVEKELSKLQRELAEA 495
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
288-788 |
6.40e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 51.31 E-value: 6.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 288 LKRLQQENMNLLS-DARSARMYRDELDALREKavrVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQ 366
Cdd:COG4717 48 LERLEKEADELFKpQGRKPELNLKELKELEEE---LKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 367 LEgtrarsdkLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQsmdeslhlgweleqisrtselseap 446
Cdd:COG4717 125 LQ--------LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAE------------------------- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 447 QKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKIlkmEKENQRLSKKVEILENEIV--QEKQSLQNC 524
Cdd:COG4717 172 LAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA---QEELEELEEELEQLENELEaaALEERLKEA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 525 QNLSKDL--MKEKAQLEKTIETLRENSERQIKILEQenehLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSK 602
Cdd:COG4717 249 RLLLLIAaaLLALLGLGGSLLSLILTIAGVLFLVLG----LLALLFLLLAREKASLGKEAEELQALPALEELEEEELEEL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 603 LSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENEL--LQKKITNL--KITCEKIEALEQeNSELERENRKLKKT 678
Cdd:COG4717 325 LAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLeeLEQEIAALlaEAGVEDEEELRA-ALEQAEEYQELKEE 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 679 LDSFKN-LTFQLESLEKENSQLDEENL--ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKtERLE 755
Cdd:COG4717 404 LEELEEqLEELLGELEELLEALDEEELeeELEELEEELEELEEELEELREELAELEAELEQLEEDGELAELLQEL-EELK 482
|
490 500 510
....*....|....*....|....*....|...
gi 208022632 756 VSYQGLDIENQRLQKTLENSNKKIQQLESELQD 788
Cdd:COG4717 483 AELRELAEEWAALKLALELLEEAREEYREERLP 515
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
578-844 |
7.15e-06 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 51.01 E-value: 7.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 578 AEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK-GERAEELENELHHLEKENELLQKKITN------ 650
Cdd:pfam06160 98 IEEDIKQILEELDELLESEEKNREEVEELKDKYRELRKTLLANRFSyGPAIDELEKQLAEIEEEFSQFEELTESgdylea 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 651 ---LKITCEKIEALEQENSELERENRKLKKTL-DSFKNLTFQLESLEKENSQLDEENLELRRNV--ESLKCASMKMAQLQ 724
Cdd:pfam06160 178 revLEKLEEETDALEELMEDIPPLYEELKTELpDQLEELKEGYREMEEEGYALEHLNVDKEIQQleEQLEENLALLENLE 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 725 LE-----NKELESEKEQLKKGLE-----------LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESE 785
Cdd:pfam06160 258 LDeaeeaLEEIEERIDQLYDLLEkevdakkyvekNLPEIEDYLEHAEEQNKELKEELERVQQSYTLNENeleRVRGLEKQ 337
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 786 LQDLEMENQTLQKNLEE-----------LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam06160 338 LEELEKRYDEIVERLEEkevayselqeeLEEILEQLEEIEEEQEEFKESLQSLRKDELEAREKLDEFKLE 407
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
241-622 |
7.37e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 51.06 E-value: 7.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNllsDARSARMYRDEldalreKAV 320
Cdd:PLN02939 39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDD---DHNRASMQRDE------AIA 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 321 RVDKLESEVSRYKERLHDIEFykarvEELKEDNQVLlETKTMLEDQlegtrARSDKLHELEK---ENLQLKAKLHDMEME 397
Cdd:PLN02939 110 AIDNEQQTNSKDGEQLSDFQL-----EDLVGMIQNA-EKNILLLNQ-----ARLQALEDLEKiltEKEALQGKINILEMR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 398 RDMDRKKIEELMEENMTLEMAQKQsmdeslhLGWELEQISRTSELSEAPQKSLGHEVNELTSsrllklemENQSLTKTVE 477
Cdd:PLN02939 179 LSETDARIKLAAQEKIHVEILEEQ-------LEKLRNELLIRGATEGLCVHSLSKELDVLKE--------ENMLLKDDIQ 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA------------QLEKTIETL 545
Cdd:PLN02939 244 FLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEKVenlqdlldratnQVEKAALVL 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 546 RENSERQIKI------LEQEN---------EHLNQTVSSLRQRSQISAEarvkDIEKENKILHESIKETSSKLSKIEFEK 610
Cdd:PLN02939 324 DQNQDLRDKVdkleasLKEANvskfssykvELLQQKLKLLEERLQASDH----EIHSYIQLYQESIKEFQDTLSKLKEES 399
|
410
....*....|..
gi 208022632 611 RqiKKELEHYKE 622
Cdd:PLN02939 400 K--KRSLEHPAD 409
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
519-714 |
7.86e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.07 E-value: 7.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 519 QSLQNCQNLS---KDLMKEKAQLEKTIETLREN-------------SERQIKILEQENEH---LNQTVSSLRQRSQISAE 579
Cdd:COG4913 201 QSFKPIGDLDdfvREYMLEEPDTFEAADALVEHfddlerahealedAREQIELLEPIRELaerYAAARERLAELEYLRAA 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 580 ARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK------------GERAEELENELHHLEKENELLQKK 647
Cdd:COG4913 281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREEldeleaqirgngGDRLEQLEREIERLERELEERERR 360
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 208022632 648 ITNLKITCEKIE-ALEQENSELERENRKLKKTLDSFKNLTFQLE----SLEKENSQLDEENLELRRNVESLK 714
Cdd:COG4913 361 RARLEALLAALGlPLPASAEEFAALRAEAAALLEALEEELEALEealaEAEAALRDLRRELRELEAEIASLE 432
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
820-1381 |
8.62e-06 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 50.88 E-value: 8.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 820 LEQETSQLEKDKKQLEKENKRLRQ---QAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKE---NKEL 893
Cdd:pfam05483 101 LKQKENKLQENRKIIEAQRKAIQElqfENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKyeyEREE 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 894 VKRATIDIKTLVTlREDLVSEKLKTQQMNNDLEKLTheleKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEiKEE 973
Cdd:pfam05483 181 TRQVYMDLNNNIE-KMILAFEELRVQAENARLEMHF----KLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITE-KEN 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 974 KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE-----ERMVQSSPPISGEDNKWERESQETTRELLKV-KDRL 1047
Cdd:pfam05483 255 KMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHltkelEDIKMSLQRSMSTQKALEEDLQIATKTICQLtEEKE 334
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1048 IEVERNN--------------ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQntTLQTQNAKLQVEnstl 1113
Cdd:pfam05483 335 AQMEELNkakaahsfvvtefeATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEM--TKFKNNKEVELE---- 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1114 nsQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVE 1193
Cdd:pfam05483 409 --ELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLK 486
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1194 HRDLEDRYNQLLKQKgqledleKMLKVEQEKMLLENKNHETVAAEYKKlcgendrlnhTYSQLLKETEVLQTDHKNLKSL 1273
Cdd:pfam05483 487 NIELTAHCDKLLLEN-------KELTQEASDMTLELKKHQEDIINCKK----------QEERMLKQIENLEEKEMNLRDE 549
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1274 LNNSKLE----QTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKD 1349
Cdd:pfam05483 550 LESVREEfiqkGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENK 629
|
570 580 590
....*....|....*....|....*....|..
gi 208022632 1350 LFHVEQRQYIDKLNELRRQKEKLEEkIMDQYK 1381
Cdd:pfam05483 630 QLNAYEIKVNKLELELASAKQKFEE-IIDNYQ 660
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
581-1343 |
9.00e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 50.82 E-value: 9.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA 660
Cdd:TIGR00606 201 KVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQ 280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 661 LEQENSELE--------------------------RENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Cdd:TIGR00606 281 MEKDNSELElkmekvfqgtdeqlndlyhnhqrtvrEKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQ 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 715 CASMKMAQLQLENkELESEKEQLKKG----LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDL- 789
Cdd:TIGR00606 361 EHIRARDSLIQSL-ATRLELDGFERGpfseRQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLg 439
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 790 ---EMENQTLQKNLEELKI----------SSKRLEQLEKENKSLEQETSQLEKDK--KQLEKENKRLRQQAEIKDTTLEE 854
Cdd:TIGR00606 440 rtiELKKEILEKKQEELKFvikelqqlegSSDRILELDQELRKAERELSKAEKNSltETLKKEVKSLQNEKADLDRKLRK 519
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 855 NNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATI---DIKTLVTLREDLVSEKLKTQQMNNDLEKLTHE 931
Cdd:TIGR00606 520 LDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSllgYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKE 599
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 932 LEKIGLNKERLLHDEQSTDDRYKLLESKL---------ESTLKKsLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKN 1002
Cdd:TIGR00606 600 LASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsqdeESDLER-LKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQS 678
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1003 YEALKQR--QDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQA 1080
Cdd:TIGR00606 679 CCPVCQRvfQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNR 758
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1081 QIlalQRQTVSLQEQNTTLQTQNAKLQVENSTLNS---------QSTSLMNQNAQLL--IQQSSLENENESVIKEREDLK 1149
Cdd:TIGR00606 759 DI---QRLKNDIEEQETLLGTIMPEEESAKVCLTDvtimerfqmELKDVERKIAQQAakLQGSDLDRTVQQVNQEKQEKQ 835
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1150 SLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLlen 1229
Cdd:TIGR00606 836 HELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDS--- 912
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1230 knheTVAAEYKKLCGENDRLNHTYSQllkETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQY-QQLDITSTKLNNQ 1308
Cdd:TIGR00606 913 ----PLETFLEKDQQEKEELISSKET---SNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYlKQKETELNTVNAQ 985
|
810 820 830
....*....|....*....|....*....|....*
gi 208022632 1309 CELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQ 1343
Cdd:TIGR00606 986 LEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDN 1020
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
661-1206 |
9.16e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 50.59 E-value: 9.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 661 LEQENSELERE----NRKLKKTLDSFKnlTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEkeq 736
Cdd:pfam10174 8 LQRENELLRREldikESKLGSSMNSIK--TFWSPELKKERALRKEEAARISVLKEQYRVTQEENQHLQLTIQALQDE--- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 737 lkkglelLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE--ELKISSKRlEQLE 814
Cdd:pfam10174 83 -------LRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEemELRIETQK-QTLG 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 815 KENKSLEQ--ETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLskeigiyKESCVRLKELEKENKE 892
Cdd:pfam10174 155 ARDESIKKllEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHL-------REELHRRNQLQPDPAK 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 893 lvkratidIKTLVTLREDLVSEKLKTQQMNNDLEkltheLEKIGLNKERLLHDEQSTDD---------RYKLLESKLEsT 963
Cdd:pfam10174 228 --------TKALQTVIEMKDTKISSLERNIRDLE-----DEVQMLKTNGLLHTEDREEEikqmevyksHSKFMKNKID-Q 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 964 LKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRqdeermvqsSPPISGEDNKWERESQETTRELLKV 1043
Cdd:pfam10174 294 LKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKESLTAKEQR---------AAILQTEVDALRLRLEEKESFLNKK 364
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1044 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQ 1123
Cdd:pfam10174 365 TKQLQDLTEEKSTLAGEIRDLKDMLDVKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSSNTDTALTTLEEA 444
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1124 NA------QLLIQQSSLEN-----ENESVIKEREDLKSLYDSLIKDHEKLEL----LHERQASEYESLISKHGTLKSAHK 1188
Cdd:pfam10174 445 LSekeriiERLKEQREREDrerleELESLKKENKDLKEKVSALQPELTEKESslidLKEHASSLASSGLKKDSKLKSLEI 524
|
570
....*....|....*...
gi 208022632 1189 NLEVEHRDLEDRYNQLLK 1206
Cdd:pfam10174 525 AVEQKKEECSKLENQLKK 542
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
550-980 |
9.39e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.54 E-value: 9.39e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 550 ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH----ESIKETSSKLSKIEFEKRQIKKELEHYKEKGE 625
Cdd:COG4717 77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKleklLQLLPLYQELEALEAELAELPERLEELEERLE 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 626 RAEELENELHHLEKENELLQkkitnlkitcEKIEALEQENSELERENrkLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Cdd:COG4717 157 ELRELEEELEELEAELAELQ----------EELEELLEQLSLATEEE--LQDLAEELEELQQRLAELEEELEEAQEELEE 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 706 LRRNVESLKcasmKMAQLQLENKELESEKEQLK----------KGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS 775
Cdd:COG4717 225 LEEELEQLE----NELEAAALEERLKEARLLLLiaaallallgLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 776 NKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDtTLEEN 855
Cdd:COG4717 301 GKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAA-LLAEA 379
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 856 NVKignLEKENKTLSKEIGIYKESCVRLKELEK--ENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELE 933
Cdd:COG4717 380 GVE---DEEELRAALEQAEEYQELKEELEELEEqlEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELA 456
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 208022632 934 KIGLNKERLlhdeqSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEA 980
Cdd:COG4717 457 ELEAELEQL-----EEDGELAELLQELE-ELKAELRELAEEWAALKL 497
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
340-1030 |
1.00e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 50.74 E-value: 1.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 340 EFYKARVEELKEDNQVLLETKTMLEDQLEgTRARSDKLH---ELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLE 416
Cdd:TIGR00618 156 QFLKAKSKEKKELLMNLFPLDQYTQLALM-EFAKKKSLHgkaELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREA 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 417 MAQKQSMDESLHLGWEL--EQISRTSELSEApQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKIL 494
Cdd:TIGR00618 235 LQQTQQSHAYLTQKREAqeEQLKKQQLLKQL-RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIH 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE---TLRENSERQiKILEQENEHLNQTVSSLR 571
Cdd:TIGR00618 314 TELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEvatSIREISCQQ-HTLTQHIHTLQQQKTTLT 392
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 572 QRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKrQIKKELEHYKEKgerAEELENELHHLEKENELLQKKITNL 651
Cdd:TIGR00618 393 QKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKK-QQELQQRYAELC---AAAITCTAQCEKLEKIHLQESAQSL 468
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 652 KitcEKIEALEQENSELERENRKlKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM----------- 720
Cdd:TIGR00618 469 K---EREQQLQTKEQIHLQETRK-KAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGeqtyaqletse 544
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 721 ----AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTL 796
Cdd:TIGR00618 545 edvyHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPE 624
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK--------KQLEKENKRLRQQAEIKDT-----------TLEENNV 857
Cdd:TIGR00618 625 QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERvrehalsiRVLPKELLASRQLALQKMQsekeqltywkeMLAQCQT 704
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 858 KIGNLEKENKTLSKEIG-IYKESCVRLKELEKEN-------KELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLT 929
Cdd:TIGR00618 705 LLRELETHIEEYDREFNeIENASSSLGSDLAAREdalnqslKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLA 784
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 930 HELEkiglNKERLLHDEQSTddrYKLLESKLESTLKKSLEIKE---EKIAALEARLEESTNYNQQLRQELKTVKKNYEAL 1006
Cdd:TIGR00618 785 AEIQ----FFNRLREEDTHL---LKTLEAEIGQEIPSDEDILNlqcETLVQEEEQFLSRLEEKSATLGEITHQLLKYEEC 857
|
730 740
....*....|....*....|....
gi 208022632 1007 KQRQDEerMVQSSPPISGEDNKWE 1030
Cdd:TIGR00618 858 SKQLAQ--LTQEQAKIIQLSDKLN 879
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
494-1300 |
1.07e-05 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 50.99 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 494 LKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEqenehLNQTVSSLRQR 573
Cdd:PTZ00440 439 LEIIEIKKKYDEKINELKKSINQLKTLISIMKSFYDLIISEKDSMDSKEKKESSDSNYQEKVDE-----LLQIINSIKEK 513
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 574 SQISAEaRVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKI 653
Cdd:PTZ00440 514 NNIVNN-NFKNIEDYYITIEGLKNEIEGLIELIKYYLQSIETLIKDEKLKRSMKNDIKNKIKYIEENVDHIKDIISLNDE 592
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 654 TCEKIEALEQENSELERENRKLKKtldsfknltfqleslEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESE 733
Cdd:PTZ00440 593 IDNIIQQIEELINEALFNKEKFIN---------------EKNDLQEKVKYILNKFYKGDLQELLDELSHFLDDHKYLYHE 657
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 734 KEQLKKGLELLKASFKKTERLEvsyqgldienqrlQKTLENSNKKIQQLESELQDL-EMENQTLQKNLEELKIS-SKRLE 811
Cdd:PTZ00440 658 AKSKEDLQTLLNTSKNEYEKLE-------------FMKSDNIDNIIKNLKKELQNLlSLKENIIKKQLNNIEQDiSNSLN 724
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIgnleKENKTLSKEIGIYKESCVRLKELEKENK 891
Cdd:PTZ00440 725 QYTIKYNDLKSSIEEYKEEEEKLEVYKHQIINRKNEFILHLYENDKDL----PDGKNTYEEFLQYKDTILNKENKISNDI 800
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 892 ELVKRATIDIKTLVTLREDLVsEKLKTQQMNNDlEKLTHELEKIGLNKE--RLLHDEQSTDDRYKLLeskleSTLKKSLE 969
Cdd:PTZ00440 801 NILKENKKNNQDLLNSYNILI-QKLEAHTEKND-EELKQLLQKFPTEDEnlNLKELEKEFNENNQIV-----DNIIKDIE 873
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 970 IKEEKIAALEaRLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKwERESQETTRELLKVKDRLIE 1049
Cdd:PTZ00440 874 NMNKNINIIK-TLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNEK-LNLLNNLNKEKEKIEKQLSD 951
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1050 VERNNATLQAEKQaLKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENstlnsqstslmnqnaqlli 1129
Cdd:PTZ00440 952 TKINNLKMQIEKT-LEYYDKSKENINGNDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILN------------------- 1011
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1130 qqsslENENESVIKEREDLKSLYDSLIKdhEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKG 1209
Cdd:PTZ00440 1012 -----KKIDDLIKKQHDDIIELIDKLIK--EKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEE 1084
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1210 QLEDLEKMLKVEQEKML-LENKNHETVAAeykkLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEaEF 1288
Cdd:PTZ00440 1085 KVEALLKKIDENKNKLIeIKNKSHEHVVN----ADKEKNKQTEHYNKKKKSLEKIYKQMEKTLKELENMNLEDITLN-EV 1159
|
810
....*....|..
gi 208022632 1289 SKLKEQYQQLDI 1300
Cdd:PTZ00440 1160 NEIEIEYERILI 1171
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
882-1373 |
1.18e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.45 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLK-TQQMNNDLEKLTHELEKIGLNKERLlhdeQSTDDRYKLLESKL 960
Cdd:PRK03918 172 KEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLReINEISSELPELREELEKLEKEVKEL----EELKEEIEELEKEL 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 961 EStLKKSLEIKEEKIAALEARLEESTNYNQQLRQ------ELKTVKKNYEALKQRQDEERMVQSSppISGEDNKWERESQ 1034
Cdd:PRK03918 248 ES-LEGSKRKLEEKIRELEERIEELKKEIEELEEkvkelkELKEKAEEYIKLSEFYEEYLDELRE--IEKRLSRLEEEIN 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1035 ETTR---ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETqnnnlqaqILALQRQTVSLQEQNTTLQTQNAKLQVENs 1111
Cdd:PRK03918 325 GIEErikELEEKEERLEELKKKLKELEKRLEELEERHELYEE--------AKAKKEELERLKKRLTGLTPEKLEKELEE- 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1112 tLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKS------LYDSLIKDHEKLELLHERQASeyesliskhgtlks 1185
Cdd:PRK03918 396 -LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpVCGRELTEEHRKELLEEYTAE-------------- 460
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1186 aHKNLEVEHRDLEDRYNQLLKQkgqLEDLEKMLKVEQEKMLLEnknheTVAAEYKKLCGENDRLNhtysqlLKETEVLQT 1265
Cdd:PRK03918 461 -LKRIEKELKEIEEKERKLRKE---LRELEKVLKKESELIKLK-----ELAEQLKELEEKLKKYN------LEELEKKAE 525
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1266 DHKNLKSLLNNSKLEQTRLEAEFSKLKEqyqqlditstkLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNM 1345
Cdd:PRK03918 526 EYEKLKEKLIKLKGEIKSLKKELEKLEE-----------LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL 594
|
490 500
....*....|....*....|....*...
gi 208022632 1346 ESKDLFHVEQRQYIDKLNELRRQKEKLE 1373
Cdd:PRK03918 595 KELEPFYNEYLELKDAEKELEREEKELK 622
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
347-580 |
1.22e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 347 EELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDES 426
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 427 LHLGWELEQISRTSELSEApqkslghevneLTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKK 506
Cdd:COG4942 107 AELLRALYRLGRQPPLALL-----------LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAE 175
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 208022632 507 VEILENEIVQEKQSLQncqnlskDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Cdd:COG4942 176 LEALLAELEEERAALE-------ALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
554-695 |
1.34e-05 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 49.78 E-value: 1.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 554 KILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKilhesiKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE-LEN 632
Cdd:PRK12704 27 KIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAK------EEIHKLRNEFEKELRERRNELQKLEKRLLQKEEnLDR 100
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 208022632 633 ELHHLEKENELLQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNLT------FQLESLEKE 695
Cdd:PRK12704 101 KLELLEKREEELEKKEKELE---QKQQELEKKEEELEELIEEQLQELERISGLTaeeakeILLEKVEEE 166
|
|
| SH3_and_anchor |
TIGR04211 |
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved ... |
716-826 |
1.38e-05 |
|
SH3 domain protein; Members of this protein family have a signal peptide, a strongly conserved SH3 domain, a variable region, and then a C-terminal hydrophobic transmembrane alpha helix region.
Pssm-ID: 275056 [Multi-domain] Cd Length: 198 Bit Score: 48.08 E-value: 1.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 716 ASMKMAQLQLENKELESEKEQLKKGLELLKASFKKterLEVSYQGLDIENQRLQKTLEnsnkKIQQLESELQDLEMENQT 795
Cdd:TIGR04211 64 ARERLPELQQELAELQEELAELQEQLAELRQENQE---LKQQLSTLEAELEELQKELE----RIKQISANAIELDEENRE 136
|
90 100 110
....*....|....*....|....*....|.
gi 208022632 796 LQKNLEELKissKRLEQLEKENKSLEQETSQ 826
Cdd:TIGR04211 137 LREELAELK---QENEALEAENERLQENEQR 164
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
583-844 |
1.44e-05 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 49.83 E-value: 1.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 583 KDIEKENKILHESIKETSSKLSKIEFEKR--------QIKKELEHYKEKGERAEELENELHHLEKENEL--LQKKITNLK 652
Cdd:PRK04778 132 LESEEKNREEVEQLKDLYRELRKSLLANRfsfgpaldELEKQLENLEEEFSQFVELTESGDYVEAREILdqLEEELAALE 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 653 ITCEKIEALEqenselerenRKLKKTL-DSFKNLTFQLESLEKENSQLDEENL--ELRRNVESLKCASMKMAQLQLE--- 726
Cdd:PRK04778 212 QIMEEIPELL----------KELQTELpDQLQELKAGYRELVEEGYHLDHLDIekEIQDLKEQIDENLALLEELDLDeae 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 727 --NKELESEKEQL----------KKGLELLKASFKKT-ERLEVSYQGLDIENQRLQKTLENSNK---KIQQLESELQDLE 790
Cdd:PRK04778 282 ekNEEIQERIDQLydilerevkaRKYVEKNSDTLPDFlEHAKEQNKELKEEIDRVKQSYTLNESeleSVRQLEKQLESLE 361
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 208022632 791 MENQTLQKNL-----------EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:PRK04778 362 KQYDEITERIaeqeiayselqEELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNK 426
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
682-1343 |
1.57e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 50.22 E-value: 1.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 682 FKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGL 761
Cdd:pfam12128 236 IMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADA 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 762 DIENQRLQKTLENSNKKIQQ---LESELQDLEMENQtLQKNLEELkisSKRLEQLEKENKSLEQETSQLEKDKKQ----- 833
Cdd:pfam12128 316 AVAKDRSELEALEDQHGAFLdadIETAAADQEQLPS-WQSELENL---EERLKALTGKHQDVTAKYNRRRSKIKEqnnrd 391
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKE-NKTLSKEIGIYKESCVRLKELEKENKELVKRATIdiktlvtlredlv 912
Cdd:pfam12128 392 IAGIKDKLAKIREARDRQLAVAEDDLQALESElREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATA------------- 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 913 SEKLKTQQMNND--LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQ 990
Cdd:pfam12128 459 TPELLLQLENFDerIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLH 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 991 QLRQELKTVKKNY-----EALKQRQDEERMVQSSPPISG-------------EDNKWERESQETTRELLKVKDrliever 1052
Cdd:pfam12128 539 FLRKEAPDWEQSIgkvisPELLHRTDLDPEVWDGSVGGElnlygvkldlkriDVPEWAASEEELRERLDKAEE------- 611
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1053 nnaTLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQlliQQS 1132
Cdd:pfam12128 612 ---ALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANE---RLN 685
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1133 SLENENESVIKEREDLKSLYDSLIKDH--EKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1210
Cdd:pfam12128 686 SLEAQLKQLDKKHQAWLEEQKEQKREArtEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGV 765
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1211 leDLEKMLKVEQEKMLLENKnHETVAAEYKKLCGENDRLNHTYSQ-------LLKETEVLQTDHK-NLKSLLNNSKLEQT 1282
Cdd:pfam12128 766 --DPDVIAKLKREIRTLERK-IERIAVRRQEVLRYFDWYQETWLQrrprlatQLSNIERAISELQqQLARLIADTKLRRA 842
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 208022632 1283 RLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLK-----GNLEEENRHLLDQIQTLMLQNRTLLEQ 1343
Cdd:pfam12128 843 KLEMERKASEKQQVRLSENLRGLRCEMSKLATLKedansEQAQGSIGERLAQLEDLKLKRDYLSES 908
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
657-867 |
1.69e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.44 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 657 KIEALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQ 736
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQA---ELEELNEEYNELQAELEALQAEIDKLQ------AEIAEAEAEIEERREE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 737 LKKGLELLKASFKKTERLEV-----SYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLE 811
Cdd:COG3883 88 LGERARALYRSGGSVSYLDVllgseSFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELE---ALKA 164
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 208022632 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Cdd:COG3883 165 ELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
371-686 |
1.71e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 49.74 E-value: 1.71e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 371 RARSDKLHELEKENLQLKAKLHDMEMERdmdRKKIEEL-------MEENMTLEMAQKQSMDESLHLGWELEQISRTSELS 443
Cdd:pfam17380 287 RQQQEKFEKMEQERLRQEKEEKAREVER---RRKLEEAekarqaeMDRQAAIYAEQERMAMERERELERIRQEERKRELE 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 444 EAPQKSLGHEVNELtsSRLLKLEMENQsltKTVEELRTTVDSvegnASKILKMEKENQRLSKKVEILENEIVQEKQSLQn 523
Cdd:pfam17380 364 RIRQEEIAMEISRM--RELERLQMERQ---QKNERVRQELEA----ARKVKILEEERQRKIQQQKVEMEQIRAEQEEAR- 433
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 524 cQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARvkdiEKENKILHESIKETSSKL 603
Cdd:pfam17380 434 -QREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAE----EQRRKILEKELEERKQAM 508
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 604 SKIEFEKRQIKKELEH-----YKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELER--ENRKLK 676
Cdd:pfam17380 509 IEEERKRKLLEKEMEErqkaiYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAMEREREMMRQivESEKAR 588
|
330
....*....|
gi 208022632 677 KTLDSFKNLT 686
Cdd:pfam17380 589 AEYEATTPIT 598
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
532-855 |
2.49e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 49.19 E-value: 2.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 532 MKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEAR---VKDIEKENKILHESIKETSSK--LSKI 606
Cdd:COG5185 235 LKGFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNENAnnlIKQFENTKEKIAEYTKSIDIKkaTESL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 607 EFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEAlEQENSELERENRKLKKTLDSFKNLT 686
Cdd:COG5185 315 EEQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVG-EVELSKSSEELDSFKDTIESTKESL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 687 FQ------------LESLEKENSQLDEENLELRRNVESlkcASMKMAQLQLENKELESEKEQLKKglellKASFKKTERL 754
Cdd:COG5185 394 DEipqnqrgyaqeiLATLEDTLKAADRQIEELQRQIEQ---ATSSNEEVSKLLNELISELNKVMR-----EADEESQSRL 465
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 755 EVSYQGLdieNQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Cdd:COG5185 466 EEAYDEI---NRSVRSKKEDLNEELTQIESRVSTLKATLEKLRAKLErQLEGVRSKLDQVAESLKDFMRARGYAHILALE 542
|
330 340
....*....|....*....|..
gi 208022632 834 LEKENKRLRQQAEIKDTTLEEN 855
Cdd:COG5185 543 NLIPASELIQASNAKTDGQAAN 564
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
685-1072 |
2.65e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 49.12 E-value: 2.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 685 LTFQLESLEKENSQLDEENLELRRNVESLKCASMKMA-QLQLENKELESEKEQLKkglELLKASFKKTERLEVSYQGLDI 763
Cdd:pfam07888 32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDReQWERQRRELESRVAELK---EELRQSREKHEELEEKYKELSA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 764 -------ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENkslEQETSQLEKDKKQLEK 836
Cdd:pfam07888 109 sseelseEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE---EAERKQLQAKLQQTEE 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 837 ENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
Cdd:pfam07888 186 ELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAA 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 917 KTQQMNNDLEKLTHELEKIGLnkerllhdeQSTDDRYKLLE-----SKLESTLKKSLEIKEEKIAALEA---RLEESTNY 988
Cdd:pfam07888 266 QRDRTQAELHQARLQAAQLTL---------QLADASLALREgrarwAQERETLQQSAEADKDRIEKLSAelqRLEERLQE 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 989 NQQLRQELKTvkknyeALKQRQDEERMVQSsppisgednkweresqETTRELLKVKDRLIEVERNNATLQAEKQALKTQL 1068
Cdd:pfam07888 337 ERMEREKLEV------ELGREKDCNRVQLS----------------ESRRELQELKASLRVAQKEKEQLQAEKQELLEYI 394
|
....
gi 208022632 1069 KQLE 1072
Cdd:pfam07888 395 RQLE 398
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
917-1119 |
3.31e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.29 E-value: 3.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEestnynqQLRQEL 996
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELE-ALQAEIDKLQAEIAEAEAEIE-------ERREEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 997 KT-VKKNYEALKQRQDEERMVQSSPP---ISGEDNkWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1072
Cdd:COG3883 89 GErARALYRSGGSVSYLDVLLGSESFsdfLDRLSA-LSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELE 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 208022632 1073 TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTS 1119
Cdd:COG3883 168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAA 214
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
464-681 |
3.56e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 48.22 E-value: 3.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 464 KLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIE 543
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 544 TLRENSERQIKILeQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK 623
Cdd:COG4942 101 AQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 208022632 624 GERAEELENELHHLEKENELLQKKITnlkitcEKIEALEQENSELERENRKLKKTLDS 681
Cdd:COG4942 180 LAELEEERAALEALKAERQKLLARLE------KELAELAAELAELQQEAEELEALIAR 231
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
978-1212 |
4.13e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 48.47 E-value: 4.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 978 LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERmvqssppisgEDNKWERESQETTRELlkvkDRLIEVERNNATL 1057
Cdd:COG3206 166 LELRREEARKALEFLEEQLPELRKELEEAEAALEEFR----------QKNGLVDLSEEAKLLL----QQLSELESQLAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1058 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVsLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENE 1137
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPV-IQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQE 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 208022632 1138 NESVIkerEDLKSLYDSLIKDHEKLEllheRQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLE 1212
Cdd:COG3206 311 AQRIL---ASLEAELEALQAREASLQ----AQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
729-926 |
4.16e-05 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 48.39 E-value: 4.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 729 ELESEKEQLKKGLELLKASFKKT-----ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEEL 803
Cdd:PRK05771 47 KLRSLLTKLSEALDKLRSYLPKLnplreEKKKVSVKSLEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 804 K----ISSKrlEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDT---------TLEENNVKIGNLEKEN---- 866
Cdd:PRK05771 127 EpwgnFDLD--LSLLLGFKYVSVFVGTVPEDKLEELKLESDVENVEYISTDkgyvyvvvvVLKELSDEVEEELKKLgfer 204
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 867 ------KTLSKEIGIYKEscvRLKELEKE----NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926
Cdd:PRK05771 205 leleeeGTPSELIREIKE---ELEEIEKEreslLEELKELAKKYLEELLALYEYLEIELERAEALSKFLK 271
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
499-852 |
4.93e-05 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 48.41 E-value: 4.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 499 ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLektietlrenSERQiKILEQE----NEHLNQTVSSLRQRS 574
Cdd:COG3096 279 ERRELSERALELRRELFGARRQLAEEQYRLVEMARELEEL----------SARE-SDLEQDyqaaSDHLNLVQTALRQQE 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 575 QI--------SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYK----EKGERAEELENELHHLEKENE 642
Cdd:COG3096 348 KIeryqedleELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQqaldVQQTRAIQYQQAVQALEKARA 427
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 643 LLQK---KITNLKITCEKIEALEQENSELERENR-KLKKTLDSFKNLTFQLESLEK-----ENSQLDEENLELRRNVESL 713
Cdd:COG3096 428 LCGLpdlTPENAEDYLAAFRAKEQQATEEVLELEqKLSVADAARRQFEKAYELVCKiagevERSQAWQTARELLRRYRSQ 507
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 714 KCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKT-------ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Cdd:COG3096 508 QALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIgqqldaaEELEELLAELEAQLEELEEQAAEAVEQRSELRQQL 587
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 787 QDLEMENQTL----------QKNLEELK------------ISSKRLEQLEKEnKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:COG3096 588 EQLRARIKELaarapawlaaQDALERLReqsgealadsqeVTAAMQQLLERE-REATVERDELAARKQALESQIERLSQP 666
|
....*...
gi 208022632 845 AEIKDTTL 852
Cdd:COG3096 667 GGAEDPRL 674
|
|
| mreC |
TIGR00219 |
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape ... |
825-943 |
5.66e-05 |
|
rod shape-determining protein MreC; MreC (murein formation C) is involved in the rod shape determination in E. coli, and more generally in cell shape determination of bacteria whether or not they are rod-shaped. Cells defective in MreC are round. Species with MreC include many of the Proteobacteria, Gram-positives, and spirochetes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 129323 [Multi-domain] Cd Length: 283 Bit Score: 47.16 E-value: 5.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 825 SQLEKDKKQLEKENKRLRQQAEIKDTTLEennVKIGNLEKENKTLSKEIGIYKescvRLKElEKENKELVKRATIDIKTL 904
Cdd:TIGR00219 62 SENLKDVNNLEYENYKLRQELLKKNQQLE---ILTQNLKQENVRLRELLNSPL----SSDE-YKISAEVIYLNYDNYSTQ 133
|
90 100 110
....*....|....*....|....*....|....*....
gi 208022632 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLL 943
Cdd:TIGR00219 134 VVINKGFNDGVYKDMPVIADGKGLVGKVVSVGSNTSRVL 172
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
262-368 |
5.67e-05 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 48.15 E-value: 5.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENmNLLSDARSARmYRDELDALREKAvrvDKLESEVSRYKERLHDIEF 341
Cdd:COG0542 401 RVRMEIDSKPEELDELERRLEQLEIEKEALKKEQ-DEASFERLAE-LRDELAELEEEL---EALKARWEAEKELIEEIQE 475
|
90 100
....*....|....*....|....*..
gi 208022632 342 YKARVEELKEDNQVLLETKTMLEDQLE 368
Cdd:COG0542 476 LKEELEQRYGKIPELEKELAELEEELA 502
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
592-961 |
5.92e-05 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 47.97 E-value: 5.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 592 LHESIKETSSKLSKIEFEKRQIKKELEHYKEKgerAEELENELHHLEKENELLQkkiTNLKITCEKIEALEQENSELERE 671
Cdd:pfam07888 36 LEECLQERAELLQAQEAANRQREKEKERYKRD---REQWERQRRELESRVAELK---EELRQSREKHEELEEKYKELSAS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 672 NrklkktldsfknltfqlESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENK-ELESEKEQLKKGLELLKASFKK 750
Cdd:pfam07888 110 S-----------------EELSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLEREtELERMKERAKKAGAQRKEEEAE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 751 TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKD 830
Cdd:pfam07888 173 RKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERK 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 831 KKQLEKE-----NKRLRQQAEIKDTTLEENNVKI-------------GNLEKENKTLSKEIGIYKESCVRL-KELEKENK 891
Cdd:pfam07888 253 VEGLGEElssmaAQRDRTQAELHQARLQAAQLTLqladaslalregrARWAQERETLQQSAEADKDRIEKLsAELQRLEE 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 892 ELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLE 961
Cdd:pfam07888 333 RLQEERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLE 402
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
599-924 |
6.31e-05 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 47.11 E-value: 6.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 599 TSSKLSKIEFEKRQIKKELEHYKEKgeraeELENELHHLEKENELLQKKITNLKITCEKIEAleqenselerenrKLKKT 678
Cdd:pfam15905 52 TARKVKSLELKKKSQKNLKESKDQK-----ELEKEIRALVQERGEQDKRLQALEEELEKVEA-------------KLNAA 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 679 LDSFKNLTFQLESLEKENSQLDEENlELRRNVESLKCASMKMAQLQLENKELESEKEQlkkglellkasfkKTERLEVSY 758
Cdd:pfam15905 114 VREKTSLSASVASLEKQLLELTRVN-ELLKAKFSEDGTQKKMSSLSMELMKLRNKLEA-------------KMKEVMAKQ 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 759 QGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN 838
Cdd:pfam15905 180 EGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEKSETEKLLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEI 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 839 KRLRQQAEIKDTTLEENnvkignlekenktlskeigiYKESCVRLKELEKENKELVKRATIDIKTLV----TLREDLVSE 914
Cdd:pfam15905 260 ESLKQSLEEKEQELSKQ--------------------IKDLNEKCKLLESEKEELLREYEEKEQTLNaeleELKEKLTLE 319
|
330
....*....|
gi 208022632 915 KLKTQQMNND 924
Cdd:pfam15905 320 EQEHQKLQQK 329
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
792-1088 |
6.48e-05 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 46.87 E-value: 6.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 792 ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSK 871
Cdd:pfam09728 2 AARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKKKQDQLQKEKDQLQSELSKAILAKSKLEKLCRELQK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 872 EIGIYK-ESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDL-EKLTHELEKIGLNKERLLHDEQST 949
Cdd:pfam09728 82 QNKKLKeESKKLAKEEEEKRKELSEKFQSTLKDIQDKMEEKSEKNNKLREENEELrEKLKSLIEQYELRELHFEKLLKTK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 950 DDRYKLLESKLESTL----KKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQ------------RQDEE 1013
Cdd:pfam09728 162 ELEVQLAEAKLQQATeeeeKKAQEKEVAKARELKAQVQTLSETEKELREQLNLYVEKFEEFQDtlnksnevfttfKKEME 241
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 208022632 1014 RMVQSSPPISGEDNKWERESQETTRELLKvkdrlievernnatLQAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Cdd:pfam09728 242 KMSKKIKKLEKENLTWKRKWEKSNKALLE--------------MAEERQKLKEELEKLQKKLEKLENLCRALQAE 302
|
|
| Tropomyosin_1 |
pfam12718 |
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and ... |
719-837 |
6.57e-05 |
|
Tropomyosin like; This family is a set of eukaryotic tropomyosins. Within the yeast Tpm1 and Tpm2, biochemical and sequence analyses indicate that Tpm2p spans four actin monomers along a filament, whereas Tpm1p spans five. Despite its shorter length, Tpm2p can compete with Tpm1p for binding to F-actin. Over-expression of Tpm2p in vivo alters the axial budding of haploids to a bipolar pattern, and this can be partially suppressed by co-over-expression of Tpm1p. This suggests distinct functions for the two tropomyosins, and indicates that the ratio between them is important for correct morphogenesis. The family also contains higher eukaryote Tpm3 members.
Pssm-ID: 403808 [Multi-domain] Cd Length: 142 Bit Score: 44.60 E-value: 6.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 719 KMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLEselQDLEMENQTLQK 798
Cdd:pfam12718 22 KVKELEQENLEKEQEIKSLTHKNQQLEEEVEKLEEQLKEAKEKAEESEKLKTNNENLTRKIQLLE---EELEESDKRLKE 98
|
90 100 110
....*....|....*....|....*....|....*....
gi 208022632 799 NLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKE 837
Cdd:pfam12718 99 TTEKLRETDVKAEHLERKVQALEQERDEWEKKYEELEEK 137
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
478-1005 |
7.75e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 47.99 E-value: 7.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILEnEIVQEKQSLQncqnlskDLMKEKAQLEKTIETLR-ENSERQIKIL 556
Cdd:COG4913 222 DTFEAADALVEHFDDLERAHEALEDAREQIELLE-PIRELAERYA-------AARERLAELEYLRAALRlWFAQRRLELL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 557 EQENEHLNQTVSSLRQRSQIsAEARVKDIEKENKILHESIKEtsSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHH 636
Cdd:COG4913 294 EAELEELRAELARLEAELER-LEARLDALREELDELEAQIRG--NGGDRLEQLEREIERLERELEERERRRARLEALLAA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 637 L-------EKENELLQKKITNLKITCEKI-EALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEENLELRR 708
Cdd:COG4913 371 LglplpasAEEFAALRAEAAALLEALEEElEALEEALAEAEAALRDLRRELRELEA---EIASLERRKSNIPARLLALRD 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 709 NVeslkCASMKMAQLQL----ENKELESEKEQLKKGLELLKASFKKT-------------------ERLEVSYQGL--DI 763
Cdd:COG4913 448 AL----AEALGLDEAELpfvgELIEVRPEEERWRGAIERVLGGFALTllvppehyaaalrwvnrlhLRGRLVYERVrtGL 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 764 ENQRLQKTLENS---------NKKIQQLESEL------------QDLEMENQTL-------------QKNLEELKISS-- 807
Cdd:COG4913 524 PDPERPRLDPDSlagkldfkpHPFRAWLEAELgrrfdyvcvdspEELRRHPRAItragqvkgngtrhEKDDRRRIRSRyv 603
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 808 ------KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE--IKDTTLEENNVKIGNLEKENKTLSKEIGIYKES 879
Cdd:COG4913 604 lgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREalQRLAEYSWDEIDVASAEREIAELEAELERLDAS 683
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 880 CVRLKELEKENKELVKRatidIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI--GLNKERLLHDEQSTDDRYK-LL 956
Cdd:COG4913 684 SDDLAALEEQLEELEAE----LEELEEELDELKGEIGRLEKELEQAEEELDELQDRleAAEDLARLELRALLEERFAaAL 759
|
570 580 590 600
....*....|....*....|....*....|....*....|....*....
gi 208022632 957 ESKLESTLKKSLeikEEKIAALEARLEestNYNQQLRQELKTVKKNYEA 1005
Cdd:COG4913 760 GDAVERELRENL---EERIDALRARLN---RAEEELERAMRAFNREWPA 802
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1038-1223 |
7.88e-05 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 47.70 E-value: 7.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1038 RELLKVKDRLIEVER---------NNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQv 1108
Cdd:COG3206 182 EQLPELRKELEEAEAaleefrqknGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELL- 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1109 ENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLydslikdhekLELLHERQASEYESLISKHGTLKSAHK 1188
Cdd:COG3206 261 QSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAAL----------RAQLQQEAQRILASLEAELEALQAREA 330
|
170 180 190
....*....|....*....|....*....|....*
gi 208022632 1189 NLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQE 1223
Cdd:COG3206 331 SLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
578-708 |
9.13e-05 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 47.55 E-value: 9.13e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 578 AEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKkELEHYKEkgeraeELENELHHLEKENELLQKKITNLKITCEK 657
Cdd:COG2433 387 EKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVE-RLEAEVE------ELEAELEEKDERIERLERELSEARSEERR 459
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 208022632 658 IEALEQENSELERENRKLKKtldsfknltfQLESLEKENSQLDEENLELRR 708
Cdd:COG2433 460 EIRKDREISRLDREIERLER----------ELEEERERIEELKRKLERLKE 500
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
779-872 |
9.76e-05 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 47.38 E-value: 9.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 779 IQQLESELQDLEMENQTLQKnlEELKISSKRLEQLEKENKSLEQETSQLekdKKQLEKENKRLRQQAEIKDtTLEENNVK 858
Cdd:COG0542 413 LDELERRLEQLEIEKEALKK--EQDEASFERLAELRDELAELEEELEAL---KARWEAEKELIEEIQELKE-ELEQRYGK 486
|
90
....*....|....
gi 208022632 859 IGNLEKENKTLSKE 872
Cdd:COG0542 487 IPELEKELAELEEE 500
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
498-711 |
1.03e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.68 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 498 KENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE----------NSERQIKILEQENEHLNQTV 567
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARriraleqelaALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 568 SSLRQR--SQISAEARVKDIEKENKILH-ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENElhhLEKENELL 644
Cdd:COG4942 100 EAQKEElaELLRALYRLGRQPPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE---LEAERAEL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 208022632 645 QKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEENLELRRNVE 711
Cdd:COG4942 177 EALLAELE---EERAALEALKAERQKLLARLEKELAELAA---ELAELQQEAEELEALIARLEAEAA 237
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
247-408 |
1.23e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.69 E-value: 1.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdarsARMYRDELDALREKAVRVDKLE 326
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKE----------IKRLELEIEEVEARIKKYEEQL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 327 SEVSRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL-HELEKENLQLKAKLHDMEMERDMDR 402
Cdd:COG1579 83 GNVRNNKEYealQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELeAELEEKKAELDEELAELEAELEELE 162
|
....*.
gi 208022632 403 KKIEEL 408
Cdd:COG1579 163 AEREEL 168
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
825-1212 |
1.25e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.07 E-value: 1.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 825 SQLEKDKKQLEKENKRLRqqaEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATiDIKTL 904
Cdd:COG4717 49 ERLEKEADELFKPQGRKP---ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELE-KLEKL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 905 VTLREDLVSEKLKTQQMNNDLEKLTHELEKIgLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEE 984
Cdd:COG4717 125 LQLLPLYQELEALEAELAELPERLEELEERL-EELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEE 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 985 STNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWER--------------------------------- 1031
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaallallglggsllsliltiagvlflvl 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1032 -----ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1106
Cdd:COG4717 284 gllalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1107 QVEnstlnsqstSLMNQNAQLLIQQSSlenENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHG--TLK 1184
Cdd:COG4717 364 QLE---------ELEQEIAALLAEAGV---EDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDeeELE 431
|
410 420
....*....|....*....|....*...
gi 208022632 1185 SAHKNLEVEHRDLEDRYNQLLKQKGQLE 1212
Cdd:COG4717 432 EELEELEEELEELEEELEELREELAELE 459
|
|
| PRK10929 |
PRK10929 |
putative mechanosensitive channel protein; Provisional |
924-1169 |
1.34e-04 |
|
putative mechanosensitive channel protein; Provisional
Pssm-ID: 236798 [Multi-domain] Cd Length: 1109 Bit Score: 46.97 E-value: 1.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 924 DLEKLTHELEKIGLNKE--------------RLLHDEQSTDDRYKLLES------KLESTLKKSLEIKEEKIAALEARLE 983
Cdd:PRK10929 24 DEKQITQELEQAKAAKTpaqaeivealqsalNWLEERKGSLERAKQYQQvidnfpKLSAELRQQLNNERDEPRSVPPNMS 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 984 eSTNYNQQLRQELKTVKKNYEALKQRQDEERMvqssppISGEDNKWERESQETTRELLKVKDRL--------IEVERNNA 1055
Cdd:PRK10929 104 -TDALEQEILQVSSQLLEKSRQAQQEQDRARE------ISDSLSQLPQQQTEARRQLNEIERRLqtlgtpntPLAQAQLT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1056 TLQAEKQALKTQLKQLETqnnnlqAQILALQRQTVS------LQEQNTTLqtqNAKLQVENSTLNSQStslmNQNAQLLI 1129
Cdd:PRK10929 177 ALQAESAALKALVDELEL------AQLSANNRQELArlrselAKKRSQQL---DAYLQALRNQLNSQR----QREAERAL 243
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 208022632 1130 QQSSLENEN-----ESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1169
Cdd:PRK10929 244 ESTELLAEQsgdlpKSIVAQFKINRELSQALNQQAQRMDLIASQQ 288
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
601-786 |
1.53e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.30 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 601 SKLSKIEFEKRQIKKELEHYKEkgeRAEELENELHHLEKENELLQKKITNLKitcekiEALEQENSELERENRKLK--KT 678
Cdd:COG1579 17 SELDRLEHRLKELPAELAELED---ELAALEARLEAAKTELEDLEKEIKRLE------LEIEEVEARIKKYEEQLGnvRN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 679 LDSFKNLTFQLESLEKENSQLDEENLELRRNVEslkcasmkmaQLQLENKELESEKEQLKKGLELLKASfkkterlevsy 758
Cdd:COG1579 88 NKEYEALQKEIESLKRRISDLEDEILELMERIE----------ELEEELAELEAELAELEAELEEKKAE----------- 146
|
170 180
....*....|....*....|....*...
gi 208022632 759 qgLDIENQRLQKTLENSNKKIQQLESEL 786
Cdd:COG1579 147 --LDEELAELEAELEELEAEREELAAKI 172
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
491-648 |
1.63e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 45.30 E-value: 1.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 491 SKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENserqikiLEQENEHLNQtVSSL 570
Cdd:COG1579 17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEAR-------IKKYEEQLGN-VRNN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 571 RQRSQI-----SAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEK-GERAEELENELHHLEKENELL 644
Cdd:COG1579 89 KEYEALqkeieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAElDEELAELEAELEELEAEREEL 168
|
....
gi 208022632 645 QKKI 648
Cdd:COG1579 169 AAKI 172
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
656-898 |
1.69e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 45.67 E-value: 1.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 656 EKIEALEQENSELERENRKLKKTLDSFKNLTFQL-ESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEK 734
Cdd:COG1340 8 SSLEELEEKIEELREEIEELKEKRDELNEELKELaEKRDELNAQVKELREEAQELREKRDELNEKVKELKEERDELNEKL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 735 EQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSN----------KKIQQLESELQDLEME---NQTLQKNLE 801
Cdd:COG1340 88 NELREELDELRKELAELNKAGGSIDKLRKEIERLEWRQQTEVlspeeekelvEKIKELEKELEKAKKAlekNEKLKELRA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 802 ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEScv 881
Cdd:COG1340 168 ELKELRKEAEEIHKKIKELAEEAQELHEEMIELYKEADELRKEADELHKEIVEAQEKADELHEEIIELQKELRELRKE-- 245
|
250
....*....|....*..
gi 208022632 882 rLKELEKENKELVKRAT 898
Cdd:COG1340 246 -LKKLRKKQRALKREKE 261
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
257-586 |
1.71e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 46.66 E-value: 1.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 257 KAKIRRLRQELEEKTEQlLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRD-ELDALREKAvrvDKLESEVSRYKER 335
Cdd:pfam17380 295 KMEQERLRQEKEEKARE-VERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERErELERIRQEE---RKRELERIRQEEI 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 336 LHDIEfykaRVEELKEDNQVLLETKTMLEDQLEGtrARSDKLHELEKenlQLKAKLHDMEMERdmDRKKIEELMEENMTL 415
Cdd:pfam17380 371 AMEIS----RMRELERLQMERQQKNERVRQELEA--ARKVKILEEER---QRKIQQQKVEMEQ--IRAEQEEARQREVRR 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 416 EMAQKQSmdeslhlgwELEQIsRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD-SVEGNASKIL 494
Cdd:pfam17380 440 LEEERAR---------EMERV-RLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEkELEERKQAMI 509
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDL-MKEKAQLEKTIETLRENSERqIKILEQENEHLNQTVSSLRQR 573
Cdd:pfam17380 510 EEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQeMEERRRIQEQMRKATEERSR-LEAMEREREMMRQIVESEKAR 588
|
330
....*....|...
gi 208022632 574 SQISAEARVKDIE 586
Cdd:pfam17380 589 AEYEATTPITTIK 601
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
839-1013 |
1.77e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.92 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 839 KRLRQQAEIkDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLvSEKLKT 918
Cdd:COG1579 7 RALLDLQEL-DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKY-EEQLGN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 919 QQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLEsTLKKSLEIKEEKIAALEARLEESTnynQQLRQELKT 998
Cdd:COG1579 85 VRNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELA-ELEAELAELEAELEEKKAELDEEL---AELEAELEE 160
|
170
....*....|....*
gi 208022632 999 VKKNYEALKQRQDEE 1013
Cdd:COG1579 161 LEAEREELAAKIPPE 175
|
|
| polC |
PRK00448 |
DNA polymerase III PolC; Validated |
638-940 |
1.85e-04 |
|
DNA polymerase III PolC; Validated
Pssm-ID: 234767 [Multi-domain] Cd Length: 1437 Bit Score: 46.75 E-value: 1.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 638 EKENELLQKKITNLKIT----CEKIEALEQENSELERENRKLKKTLDSFKNLTFQL-----ESLEKENSQLDEENLELRR 708
Cdd:PRK00448 1 NEMQEKFKKLLDQINIPddlqSEALESAEIEKVVVDKKSKKWEFHLKFPNILPIEDfklfkEKLKQSFSHIADIKVTFSI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 709 NVESLKCasmkmaQLQLENKELESEKEQLKKGLELLKASFKKTE------RLEVSYQGlDIENQRL-QKTLENSNKKIQQ 781
Cdd:PRK00448 81 EVENITF------TEELLLDYWNEIIEKAKKNSPLFKSLLKKQKvevegnKLIIKVNN-EIERDHLkKKHLPKLIKQYEK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 782 LESELqdLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENK---------RLRQQAEI---KD 849
Cdd:PRK00448 154 FGFGI--LKIDFEIDDSKEELEKFEAQKEEEDEKLAKEALEAMKKLEAEKKKQSKNFDpkegpvqigKKIDKEEItpmKE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 850 TTLEENNVKI-G--------NLEKENKTLSKEIGIYKEScVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL-KTQ 919
Cdd:PRK00448 232 INEEERRVVVeGyvfkveikELKSGRHILTFKITDYTSS-IIVKKFSRDKEDLKKFDEIKKGDWVKVRGSVQNDTFtRDL 310
|
330 340
....*....|....*....|..
gi 208022632 920 QMN-NDLEKLTHELEKIGLNKE 940
Cdd:PRK00448 311 VMNaQDINEIKHPERKDTAEEE 332
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
956-1154 |
1.97e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.98 E-value: 1.97e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 956 LESKLEStLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKknyEALKQRQDE--ERMVQSSppISGEDNKWERE- 1032
Cdd:COG3883 35 AQAELDA-LQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAE---AEIEERREElgERARALY--RSGGSVSYLDVl 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1033 -SQETTRELLkvkDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENS 1111
Cdd:COG3883 109 lGSESFSDFL---DRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQAEQEALLA 185
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 208022632 1112 TLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDS 1154
Cdd:COG3883 186 QLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAA 228
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
706-896 |
2.14e-04 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 45.92 E-value: 2.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 706 LRRNVESLKCASMK-MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEvsyQGLDIENQRLQKTLENSNKKIQQLES 784
Cdd:PRK12704 24 VRKKIAEAKIKEAEeEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFE---KELRERRNELQKLEKRLLQKEENLDR 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 785 ELQDLEmenqtlqknleelkissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE-IKDTTLEE-NNVKIGNL 862
Cdd:PRK12704 101 KLELLE-----------------KREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELErISGLTAEEaKEILLEKV 163
|
170 180 190
....*....|....*....|....*....|....
gi 208022632 863 EKENKTlskeigiykESCVRLKELEKENKELVKR 896
Cdd:PRK12704 164 EEEARH---------EAAVLIKEIEEEAKEEADK 188
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
247-422 |
2.63e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.59 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 247 QHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSAR-MYRDELDALREKAVRVDKL 325
Cdd:COG3883 26 SELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERReELGERARALYRSGGSVSYL 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 326 E-----SEVSRYKERLHDI----EFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKL----HELEKENLQLKAKLH 392
Cdd:COG3883 106 DvllgsESFSDFLDRLSALskiaDADADLLEELKADKAELEAKKAELEAKLAELEALKAELeaakAELEAQQAEQEALLA 185
|
170 180 190
....*....|....*....|....*....|
gi 208022632 393 DMEMERDMDRKKIEELMEENMTLEMAQKQS 422
Cdd:COG3883 186 QLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
240-573 |
2.89e-04 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 46.10 E-value: 2.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 240 MKRTESRQHLSVELADAkakirrlRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSArmyRDELdALREKA 319
Cdd:COG3096 274 MRHANERRELSERALEL-------RRELFGARRQLAEEQYRLVEMARELEELSARESDLEQDYQAA---SDHL-NLVQTA 342
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 320 VRvdkLESEVSRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARsdkLHELEKENLQLKAKLHDMEMERD 399
Cdd:COG3096 343 LR---QQEKIERYQEDLEELT------ERLEEQEEVVEE----AAEQLAEAEAR---LEAAEEEVDSLKSQLADYQQALD 406
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 400 MDRKKIEELMEENMTLEMAQKQSMDESLHlgweLEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEEL 479
Cdd:COG3096 407 VQQTRAIQYQQAVQALEKARALCGLPDLT----PENAEDYLAAFRAKEQQATEEVLEL-EQKLSVADAARRQFEKAYELV 481
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 480 RTTVDSVE-----GNASKILKMEKENQRLSKKVEILE---NEIVQEKQSLQNCQNLSKDLMK--------------EKAQ 537
Cdd:COG3096 482 CKIAGEVErsqawQTARELLRRYRSQQALAQRLQQLRaqlAELEQRLRQQQNAERLLEEFCQrigqqldaaeeleeLLAE 561
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 208022632 538 LEKTIETL----RENSERQIKiLEQENEHLNQTVSSLRQR 573
Cdd:COG3096 562 LEAQLEELeeqaAEAVEQRSE-LRQQLEQLRARIKELAAR 600
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
722-873 |
3.15e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 3.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEME----NQTLQ 797
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREElgerARALY 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 798 KN------LEEL-----------------KISS---KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTT 851
Cdd:COG3883 97 RSggsvsyLDVLlgsesfsdfldrlsalsKIADadaDLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176
|
170 180
....*....|....*....|..
gi 208022632 852 LEENNVKIGNLEKENKTLSKEI 873
Cdd:COG3883 177 QAEQEALLAQLSAEEAAAEAQL 198
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
596-826 |
3.41e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 3.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 596 IKETSSKLSKIEFEKRQIKKELehyKEKGERAEELENELHHLEKENELLQKKITNLKitcEKIEALEQE----NSELERE 671
Cdd:COG3883 18 IQAKQKELSELQAELEAAQAEL---DALQAELEELNEEYNELQAELEALQAEIDKLQ---AEIAEAEAEieerREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 672 NRKLKKTLDSFKNLTFQLESlekensqldeENL-ELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLEllkasfKK 750
Cdd:COG3883 92 ARALYRSGGSVSYLDVLLGS----------ESFsDFLDRLSALSKIADADADLLEELKADKAELEAKKAELE------AK 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 208022632 751 TERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQ 826
Cdd:COG3883 156 LAELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAA 231
|
|
| Taxilin |
pfam09728 |
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain ... |
639-935 |
3.66e-04 |
|
Myosin-like coiled-coil protein; Taxilin contains an extraordinarily long coiled-coil domain in its C-terminal half and is ubiquitously expressed. It is a novel binding partner of several syntaxin family members and is possibly involved in Ca2+-dependent exocytosis in neuroendocrine cells. Gamma-taxilin, described as leucine zipper protein Factor Inhibiting ATF4-mediated Transcription (FIAT), localizes to the nucleus in osteoblasts and dimerizes with ATF4 to form inactive dimers, thus inhibiting ATF4-mediated transcription.
Pssm-ID: 462861 [Multi-domain] Cd Length: 302 Bit Score: 44.56 E-value: 3.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 639 KENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNltfQLESLEKENSQLDEEN---LELRRNVESLkc 715
Cdd:pfam09728 1 KAARELMQLLNKLDSPEEKLAALCKKYAELLEEMKRLQKDLKKLKK---KQDQLQKEKDQLQSELskaILAKSKLEKL-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 716 asmkMAQLQLENKELESEKEQLKKGLE----LLKASFKKTeRLEVSYQGLDIENQRLQKTLENSN--KKIQQL--ESELQ 787
Cdd:pfam09728 76 ----CRELQKQNKKLKEESKKLAKEEEekrkELSEKFQST-LKDIQDKMEEKSEKNNKLREENEElrEKLKSLieQYELR 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 788 DLEMENQTLQKNLE----ELKISSKRLEQlEKENKSLEQETSQLEKDK-KQLEKENKRLRQQAEIK-------DTTLEEN 855
Cdd:pfam09728 151 ELHFEKLLKTKELEvqlaEAKLQQATEEE-EKKAQEKEVAKARELKAQvQTLSETEKELREQLNLYvekfeefQDTLNKS 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 856 NVKIGNLEKENKTLSKEIgiykescvrlKELEKENKELVKRATIDIKTLVtlreDLVSEKLKTQQMNNDLEKLTHELEKI 935
Cdd:pfam09728 230 NEVFTTFKKEMEKMSKKI----------KKLEKENLTWKRKWEKSNKALL----EMAEERQKLKEELEKLQKKLEKLENL 295
|
|
| Mitofilin |
pfam09731 |
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. ... |
420-677 |
4.56e-04 |
|
Mitochondrial inner membrane protein; Mitofilin controls mitochondrial cristae morphology. Mitofilin is enriched in the narrow space between the inner boundary and the outer membranes, where it forms a homotypic interaction and assembles into a large multimeric protein complex. The first 78 amino acids contain a typical amino-terminal-cleavable mitochondrial presequence rich in positive-charged and hydroxylated residues and a membrane anchor domain. In addition, it has three centrally located coiled coil domains.
Pssm-ID: 430783 [Multi-domain] Cd Length: 618 Bit Score: 45.13 E-value: 4.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 420 KQSMDESLHLGWELEQISRTSElsEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKE 499
Cdd:pfam09731 167 KEASDTAEISREKATDSALQKA--EALAEKLKEVINLAKQSEEEAAPPLLDAAPETPPKLPEHLDNVEEKVEKAQSLAKL 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 500 NQRLSKKVEILENEIVQEKQSLQN--CQNLSKDLMKEKA--------------QLEKTIETLRENSERQI-KILEQENEH 562
Cdd:pfam09731 245 VDQYKELVASERIVFQQELVSIFPdiIPVLKEDNLLSNDdlnsliahahreidQLSKKLAELKKREEKHIeRALEKQKEE 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 563 LNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELH-----HL 637
Cdd:pfam09731 325 LDKLAEELSARLEEVRAADEAQLRLEFEREREEIRESYEEKLRTELERQAEAHEEHLKDVLVEQEIELQREFLqdikeKV 404
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 208022632 638 EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKK 677
Cdd:pfam09731 405 EEERAGRLLKLNELLANLKGLEKATSSHSEVEDENRKAQQ 444
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1197-1376 |
4.74e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.14 E-value: 4.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1197 LEDRYNQLLKQKG--------QLEDLEKMLKVEQEKMllenknhetvaAEYKKLCGENDRLNHTYSQLLKETEVLQTDHK 1268
Cdd:COG4717 51 LEKEADELFKPQGrkpelnlkELKELEEELKEAEEKE-----------EEYAELQEELEELEEELEELEAELEELREELE 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1269 NLKSLLNNSKLEQTR--LEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNME 1346
Cdd:COG4717 120 KLEKLLQLLPLYQELeaLEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAE 199
|
170 180 190
....*....|....*....|....*....|
gi 208022632 1347 SKDLFHVEQRQYIDKLNELRRQKEKLEEKI 1376
Cdd:COG4717 200 ELEELQQRLAELEEELEEAQEELEELEEEL 229
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
759-896 |
4.79e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.76 E-value: 4.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 759 QGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQL--------------------EKENK 818
Cdd:COG1579 13 QELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEieevearikkyeeqlgnvrnNKEYE 92
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 208022632 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI-GIYKESCVRLKELEKENKELVKR 896
Cdd:COG1579 93 ALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELdEELAELEAELEELEAEREELAAK 171
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
240-668 |
5.03e-04 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 45.33 E-value: 5.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 240 MKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnlLSDArsarmyRDELDALREKA 319
Cdd:PRK04863 275 MRHANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQD----YQAA------SDHLNLVQTAL 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 320 VRVDKLEsevsRYKERLHDIEfykarvEELKEDNQVLLEtktmLEDQLEGTRARSDklhELEKENLQLKAKLHDMEMERD 399
Cdd:PRK04863 345 RQQEKIE----RYQADLEELE------ERLEEQNEVVEE----ADEQQEENEARAE---AAEEEVDELKSQLADYQQALD 407
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 400 MDRKKIEELMEENMTLEMAQKQSMDESLhlgwELEQISRTSELSEAPQKSLGHEVNELtSSRLLKLEMENQSLTKTVEEL 479
Cdd:PRK04863 408 VQQTRAIQYQQAVQALERAKQLCGLPDL----TADNAEDWLEEFQAKEQEATEELLSL-EQKLSVAQAAHSQFEQAYQLV 482
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 480 RTTVDSVEGN-----ASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIK 554
Cdd:PRK04863 483 RKIAGEVSRSeawdvARELLRRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEE 562
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 555 iLEQENEHLNQTVSSLRQRSqisaeARVKDIEKENKILHEsiketssKLSKIEFEKRQIKKEL----EHYKEKGERAEEL 630
Cdd:PRK04863 563 -LEARLESLSESVSEARERR-----MALRQQLEQLQARIQ-------RLAARAPAWLAAQDALarlrEQSGEEFEDSQDV 629
|
410 420 430
....*....|....*....|....*....|....*....
gi 208022632 631 ENEL-HHLEKENELLQKKITnlkiTCEKIEALEQENSEL 668
Cdd:PRK04863 630 TEYMqQLLERERELTVERDE----LAARKQALDEEIERL 664
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
410-1075 |
5.32e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.81 E-value: 5.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 410 EENMTLEMaQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgn 489
Cdd:pfam10174 67 EENQHLQL-TIQALQDELRAQRDLNQLLQQDFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKELFLLRKTLEEME-- 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 490 askiLKMEKENQRLSKKveileNEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSS 569
Cdd:pfam10174 144 ----LRIETQKQTLGAR-----DESIKKLLEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQKEKENIHLREE 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 570 LRQRSQISAEArvkdieKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGEraeeleneLHHLEKENELLQKKI- 648
Cdd:pfam10174 215 LHRRNQLQPDP------AKTKALQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGL--------LHTEDREEEIKQMEVy 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 649 -TNLKITCEKIEALEQENSELERENRKLKKTLDSFKN-----------LTFQLESLEKENSQLDEENLELRRNVES---- 712
Cdd:pfam10174 281 kSHSKFMKNKIDQLKQELSKKESELLALQTKLETLTNqnsdckqhievLKESLTAKEQRAAILQTEVDALRLRLEEkesf 360
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 713 LKCASMKMAQLQLENKELESEKEQLKKGLELLKASF----KKTERL-------EVSYQGLDIENQRLQKTLENSNKKIQQ 781
Cdd:pfam10174 361 LNKKTKQLQDLTEEKSTLAGEIRDLKDMLDVKERKInvlqKKIENLqeqlrdkDKQLAGLKERVKSLQTDSSNTDTALTT 440
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 782 LESELQDLEMENQTLQKNLE-ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeikdTTLEENNVKIG 860
Cdd:pfam10174 441 LEEALSEKERIIERLKEQRErEDRERLEELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHA----SSLASSGLKKD 516
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 861 NlekENKTLSKEIGIYKESCVRLKELEK--ENKELVKRATIDIKTLVTLREDLVS----EKLKTQQMNNDLEKLTHELEK 934
Cdd:pfam10174 517 S---KLKSLEIAVEQKKEECSKLENQLKkaHNAEEAVRTNPEINDRIRLLEQEVArykeESGKAQAEVERLLGILREVEN 593
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 935 IGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAAL--EARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1012
Cdd:pfam10174 594 EKNDKDKKIAELESLTLRQMKEQNKKVANIKHGQQEMKKKGAQLleEARRREDNLADNSQQLQLEELMGALEKTRQELDA 673
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1013 ERMVQSSPPIS-----GEDNKWERESQETTRELLKVKDR--------------LIEVERNN--------ATLQAEKQALK 1065
Cdd:pfam10174 674 TKARLSSTQQSlaekdGHLTNLRAERRKQLEEILEMKQEallaaisekdaniaLLELSSSKkkktqeevMALKREKDRLV 753
|
730
....*....|
gi 208022632 1066 TQLKQlETQN 1075
Cdd:pfam10174 754 HQLKQ-QTQN 762
|
|
| Uso1_p115_C |
pfam04871 |
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular ... |
777-873 |
5.34e-04 |
|
Uso1 / p115 like vesicle tethering protein, C terminal region; Also known as General vesicular transport factor, Transcytosis associate protein (TAP) and Vesicle docking protein, this myosin-shaped molecule consists of an N-terminal globular head region, a coiled-coil tail which mediates dimerization, and a short C-terminal acidic region. p115 tethers COP1 vesicles to the Golgi by binding the coiled coil proteins giantin (on the vesicles) and GM130 (on the Golgi), via its C-terminal acidic region. It is required for intercisternal transport in the golgi stack. This family consists of the acidic C-terminus, which binds to the golgins giantin and GM130. p115 is thought to juxtapose two membranes by binding giantin with one acidic region, and GM130 with another.
Pssm-ID: 461461 [Multi-domain] Cd Length: 121 Bit Score: 41.62 E-value: 5.34e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Cdd:pfam04871 1 AKKSELESEASSLKNENTELKAELQELSKQYNSLEQKESQAKELEAEVKKLEEALKKLKAELSEEKQKEKEKQSELDDLL 80
|
90
....*....|....*..
gi 208022632 857 VKIGNLEKENKTLSKEI 873
Cdd:pfam04871 81 LLLGDLEEKVEKYKARL 97
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
343-572 |
5.39e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.62 E-value: 5.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 343 KARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKaklhdmemerdmdRKKIEELMEENMTLEMAQKQS 422
Cdd:PHA02562 173 KDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARK-------------QNKYDELVEEAKTIKAEIEEL 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 423 MDESLHLgwELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEK---- 498
Cdd:PHA02562 240 TDELLNL--VMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQHslek 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 499 -------------ENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTietlRENSERQIKILEQENEHLNQ 565
Cdd:PHA02562 318 ldtaideleeimdEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAE----FVDNAEELAKLQDELDKIVK 393
|
....*..
gi 208022632 566 TVSSLRQ 572
Cdd:PHA02562 394 TKSELVK 400
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
883-1120 |
6.18e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.62 E-value: 6.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 883 LKELEKENKELVKRATIDIKTLvTLREDLVSEKLKTQQmnndleKLTHELEKiglnkerllhdeqSTDDRYKLLESKLES 962
Cdd:PHA02562 165 LSEMDKLNKDKIRELNQQIQTL-DMKIDHIQQQIKTYN------KNIEEQRK-------------KNGENIARKQNKYDE 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 963 TLKKSLEIK------EEKIAALEARLEESTNYNQQLRQELKTVKKNyeaLKQRQDEERMVQS-------SPPISGEDNKW 1029
Cdd:PHA02562 225 LVEEAKTIKaeieelTDELLNLVMDIEDPSAALNKLNTAAAKIKSK---IEQFQKVIKMYEKggvcptcTQQISEGPDRI 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1030 ER------ESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQN 1103
Cdd:PHA02562 302 TKikdklkELQHSLEKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEEL 381
|
250
....*....|....*..
gi 208022632 1104 AKLQVENSTLNSQSTSL 1120
Cdd:PHA02562 382 AKLQDELDKIVKTKSEL 398
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
652-895 |
6.23e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 44.62 E-value: 6.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 652 KITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQldeenlELRRNVESLKCasmKMAQLQLENKELE 731
Cdd:PHA02562 170 KLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIA------RKQNKYDELVE---EAKTIKAEIEELT 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 732 SEKEQLKKGLELLKASFKKterlevsyqgLDIENQRLQKTLENSNKKIQQLESE------LQDLEMENQTLQKNLEELKI 805
Cdd:PHA02562 241 DELLNLVMDIEDPSAALNK----------LNTAAAKIKSKIEQFQKVIKMYEKGgvcptcTQQISEGPDRITKIKDKLKE 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 806 SSKRLEQLEKEnkslEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKEScvrLKE 885
Cdd:PHA02562 311 LQHSLEKLDTA----IDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEE---LAK 383
|
250
....*....|
gi 208022632 886 LEKENKELVK 895
Cdd:PHA02562 384 LQDELDKIVK 393
|
|
| DUF3498 |
pfam12004 |
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. ... |
801-850 |
6.35e-04 |
|
Domain of unknown function (DUF3498); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 433 to 538 amino acids in length. This domain is found associated with pfam00616, pfam00168. This domain has two conserved sequence motifs: DLQ and PLSFQNP.
Pssm-ID: 463427 [Multi-domain] Cd Length: 511 Bit Score: 44.36 E-value: 6.35e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 208022632 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQ-LEKENKRLRQQAEIKDT 850
Cdd:pfam12004 399 ERLRVSNRKLEEYERRLLAQEEQTQKLLLEYQArLEDSEERLRRQQEEKDS 449
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
579-750 |
6.40e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 43.37 E-value: 6.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 579 EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKItcekI 658
Cdd:COG1579 16 DSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE----Y 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 659 EALEQENSELERENRKLKKTLdsfKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLK 738
Cdd:COG1579 92 EALQKEIESLKRRISDLEDEI---LELMERIEELEEELAELEAELAELEAELEEKK------AELDEELAELEAELEELE 162
|
170
....*....|..
gi 208022632 739 KGLELLKASFKK 750
Cdd:COG1579 163 AEREELAAKIPP 174
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
719-896 |
6.99e-04 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 42.61 E-value: 6.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 719 KMAQLQLENKELESEKEQLKKGLELLKASfkKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQK 798
Cdd:pfam08614 15 RTALLEAENAKLQSEPESVLPSTSSSKLS--KASPQSASIQSLEQLLAQLREELAELYRSRGELAQRLVDLNEELQELEK 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 799 NLEElkiSSKRLEQLEKENKSLEQEtsqlekdKKQLEKENKRLRQQAEIkdttleennvkignLEKENKTLSKEIGIYKE 878
Cdd:pfam08614 93 KLRE---DERRLAALEAERAQLEEK-------LKDREEELREKRKLNQD--------------LQDELVALQLQLNMAEE 148
|
170
....*....|....*...
gi 208022632 879 scvRLKELEKENKELVKR 896
Cdd:pfam08614 149 ---KLRKLEKENRELVER 163
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
659-1009 |
9.39e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.74 E-value: 9.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 659 EALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKELESEKEQLK 738
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELN------EQLQAAQAELAQAQEELE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 739 KGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK 818
Cdd:COG4372 105 SLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 819 SLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRAT 898
Cdd:COG4372 185 LDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELE 264
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 899 IDIktlvtlREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAAL 978
Cdd:COG4372 265 LAI------LVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAE 338
|
330 340 350
....*....|....*....|....*....|.
gi 208022632 979 EARLEESTNYNQQLRQELKTVKKNYEALKQR 1009
Cdd:COG4372 339 LADLLQLLLVGLLDNDVLELLSKGAEAGVAD 369
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
974-1382 |
1.03e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 44.06 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 974 KIAALEARLEEStnYNQQLRQELKTVKKnyealkqrqdeermvqssPPISGED----NKWERESQE-TTRELLKVKDRLI 1048
Cdd:PRK04778 30 RIDELEERKQEL--ENLPVNDELEKVKK------------------LNLTGQSeekfEEWRQKWDEiVTNSLPDIEEQLF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1049 EVERNNAT--LQAEKQALKT---QLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQvenSTLNSQSTS---- 1119
Cdd:PRK04778 90 EAEELNDKfrFRKAKHEINEiesLLDLIEEDIEQILEELQELLESEEKNREEVEQLKDLYRELR---KSLLANRFSfgpa 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1120 ---LMNQNAQLLIQQSSLENENES--VIKEREDLKSLYDSLI---KDHEKLELLHERQASEYESLISKhgtLKSAHKNLE 1191
Cdd:PRK04778 167 ldeLEKQLENLEEEFSQFVELTESgdYVEAREILDQLEEELAaleQIMEEIPELLKELQTELPDQLQE---LKAGYRELV 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1192 VEHRDLEDrynqlLKQKGQLEDLEKmlKVEQEKMLLENKNHETVAAEYKKLcgeNDRLNHTYSQLLKETE---VLQTDHK 1268
Cdd:PRK04778 244 EEGYHLDH-----LDIEKEIQDLKE--QIDENLALLEELDLDEAEEKNEEI---QERIDQLYDILEREVKarkYVEKNSD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1269 NLKSLLNNSKLEQTRLEAEFSKLKEQYQqldITSTKLNNQCELLSQLKgNLEEENRHLLDQI--QTL---MLQNRtlLEQ 1343
Cdd:PRK04778 314 TLPDFLEHAKEQNKELKEEIDRVKQSYT---LNESELESVRQLEKQLE-SLEKQYDEITERIaeQEIaysELQEE--LEE 387
|
410 420 430
....*....|....*....|....*....|....*....
gi 208022632 1344 NMESKDLFHVEQRQYIDKLNELRRQKEKLEEKImDQYKF 1382
Cdd:PRK04778 388 ILKQLEEIEKEQEKLSEMLQGLRKDELEAREKL-ERYRN 425
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
495-809 |
1.05e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 44.12 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 495 KMEKENQRLSKKVEIL--------ENEIVQEKQSLQNCQNLSKdLMKEKAQLEKTIETLREN---SERQIKILEQENEHL 563
Cdd:PLN02939 118 NSKDGEQLSDFQLEDLvgmiqnaeKNILLLNQARLQALEDLEK-ILTEKEALQGKINILEMRlseTDARIKLAAQEKIHV 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 564 NQTVSSLRQ-RSQISAEarvkdIEKENKILHESIKEtsskLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENE 642
Cdd:PLN02939 197 EILEEQLEKlRNELLIR-----GATEGLCVHSLSKE----LDVLKEENMLLKDDIQFLKAELIEVAETEERVFKLEKERS 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 643 LLqkkitnlkitcekiealeqENSELERENRKLKKTLDSFKNLTFQLESL-EKensqldEENLELRrnVESLKCASMKMA 721
Cdd:PLN02939 268 LL-------------------DASLRELESKFIVAQEDVSKLSPLQYDCWwEK------VENLQDL--LDRATNQVEKAA 320
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDlemenqtLQKNLE 801
Cdd:PLN02939 321 LVLDQNQDLRDKVDKLEASLKEANVSKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQESIKE-------FQDTLS 393
|
....*...
gi 208022632 802 ELKISSKR 809
Cdd:PLN02939 394 KLKEESKK 401
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
792-843 |
1.10e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 43.67 E-value: 1.10e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 208022632 792 ENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Cdd:PRK03992 2 RLEALEERNSELE---EQIRQLELKLRDLEAENEKLERELERLKSELEKLKS 50
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
490-711 |
1.16e-03 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 43.69 E-value: 1.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 490 ASKIL-KMEKENQRLSKKVEILENEIVQEKQS----LQNCQNLSKDLMKEK-----AQLEKTIETLRENSERQIKIL--- 556
Cdd:pfam06160 177 AREVLeKLEEETDALEELMEDIPPLYEELKTElpdqLEELKEGYREMEEEGyalehLNVDKEIQQLEEQLEENLALLenl 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 557 -----EQENEHLNQTVSSLrqrsqisaearVKDIEKE---NKILHESIKETSSKLSKIEFEKRQIKKELEHYK------- 621
Cdd:pfam06160 257 eldeaEEALEEIEERIDQL-----------YDLLEKEvdaKKYVEKNLPEIEDYLEHAEEQNKELKEELERVQqsytlne 325
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 622 EKGERAEELENELHHLEKENELLQKKITNLKIT----CEKIEALEQENSELERENRKLKKTLDSfknltfqLESLEKEN- 696
Cdd:pfam06160 326 NELERVRGLEKQLEELEKRYDEIVERLEEKEVAyselQEELEEILEQLEEIEEEQEEFKESLQS-------LRKDELEAr 398
|
250
....*....|....*...
gi 208022632 697 ---SQLDEENLELRRNVE 711
Cdd:pfam06160 399 eklDEFKLELREIKRLVE 416
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1039-1239 |
1.21e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.28 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1039 ELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKLQVENSTLNSQST 1118
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAE---IAEAEAEIEERREELGERAR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1119 SLMNQNAQLLIQQSSLENEN-ESVIKEREDLKSLYDS---LIKDHEKLELLHERQASEYESLISKhgtLKSAHKNLEVEH 1194
Cdd:COG3883 94 ALYRSGGSVSYLDVLLGSESfSDFLDRLSALSKIADAdadLLEELKADKAELEAKKAELEAKLAE---LEALKAELEAAK 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 208022632 1195 RDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEY 1239
Cdd:COG3883 171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAA 215
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
945-1109 |
1.21e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 945 DEQSTDDRYKLLESKLeSTLKKSLEIKEEKIAALEARLEESTN---------YNQQLRQELKTVKKNYEALKQRQDEE-- 1013
Cdd:COG3206 213 EAKLLLQQLSELESQL-AEARAELAEAEARLAALRAQLGSGPDalpellqspVIQQLRAQLAELEAELAELSARYTPNhp 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1014 RMVQssppisgednkwERESQETTRELLK--VKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL---QAQILALQRQ 1088
Cdd:COG3206 292 DVIA------------LRAQIAALRAQLQqeAQRILASLEAELEALQAREASLQAQLAQLEARLAELpelEAELRRLERE 359
|
170 180
....*....|....*....|.
gi 208022632 1089 TVSLQEQNTTLQTQNAKLQVE 1109
Cdd:COG3206 360 VEVARELYESLLQRLEEARLA 380
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
434-690 |
1.34e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 43.76 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 434 EQISRTSELSEAPQKsLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEgnaSKILKMEKENQRLSKKVEILEne 513
Cdd:PRK05771 47 KLRSLLTKLSEALDK-LRSYLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIE---KEIKELEEEISELENEIKELE-- 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 514 ivQEKQSLQNCQNLSKDLmkEKAQLEKTIE----TLRENSERQIKILEQENEHLnqTVSSLRQRSQISAEARVKDIEKEN 589
Cdd:PRK05771 121 --QEIERLEPWGNFDLDL--SLLLGFKYVSvfvgTVPEDKLEELKLESDVENVE--YISTDKGYVYVVVVVLKELSDEVE 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 590 KILhesiketssklSKIEFEKRQIKKE---LEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEkiEALEQens 666
Cdd:PRK05771 195 EEL-----------KKLGFERLELEEEgtpSELIREIKEELEEIEKERESLLEELKELAKKYLEELLALY--EYLEI--- 258
|
250 260
....*....|....*....|....*.
gi 208022632 667 ELEREN--RKLKKTldsfkNLTFQLE 690
Cdd:PRK05771 259 ELERAEalSKFLKT-----DKTFAIE 279
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1030-1210 |
1.43e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 43.28 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1030 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQ----TVSLQEQNTTLQTQNAK 1105
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEiaeaEAEIEERREELGERARA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1106 LQVENST-------LNSQSTS-----------LMNQNAQLLIQQSS----LENENESVIKEREDLKSLYDSLIKDHEKLE 1163
Cdd:COG3883 95 LYRSGGSvsyldvlLGSESFSdfldrlsalskIADADADLLEELKAdkaeLEAKKAELEAKLAELEALKAELEAAKAELE 174
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 208022632 1164 LLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQ 1210
Cdd:COG3883 175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
571-846 |
1.68e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 1.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 571 RQRSQISAE-ARVKDIEKENKILHESIKETSSKLSKIE-----FEKRQIKKELEHYKEKGERAEELENELHHLEKENELL 644
Cdd:COG3096 843 QRRSELERElAQHRAQEQQLRQQLDQLKEQLQLLNKLLpqanlLADETLADRLEELREELDAAQEAQAFIQQHGKALAQL 922
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 645 QKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENS-QLDEENLELrrnVESLKcasmkmAQL 723
Cdd:COG3096 923 EPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAvGLLGENSDL---NEKLR------ARL 993
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 724 QLENKELESEKEQLKKglellkasfkKTERLEVSYQGLdienQRLQKTLENSNKKIQQLESELQDL------EMENQTLQ 797
Cdd:COG3096 994 EQAEEARREAREQLRQ----------AQAQYSQYNQVL----ASLKSSRDAKQQTLQELEQELEELgvqadaEAEERARI 1059
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 208022632 798 KNLE---ELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:COG3096 1060 RRDElheELSQNRSRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVV 1111
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
252-351 |
1.75e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 43.31 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQEnmnllsdARSARMYRDELDALREkavRVDKLESEVSR 331
Cdd:COG2433 414 EIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE-------ERREIRKDREISRLDR---EIERLERELEE 483
|
90 100
....*....|....*....|
gi 208022632 332 YKERLHDIefyKARVEELKE 351
Cdd:COG2433 484 ERERIEEL---KRKLERLKE 500
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
1035-1113 |
1.77e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 41.07 E-value: 1.77e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 208022632 1035 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1113
Cdd:pfam08614 82 DLNEELQELEKKLREDERRLAALEAERAQLEEKLKDREEELREKRKLNQDLQDELVALQLQLNMAEEKLRKLEKENREL 160
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
255-741 |
2.05e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 43.11 E-value: 2.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 255 DAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMN--------LLSDARSARMYRDELDALREKAVRVDKLE 326
Cdd:TIGR00606 636 DEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSccpvcqrvFQTEAELQEFISDLQSKLRLAPDKLKSTE 715
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 327 SEVSRyKERLHDIEFYKARVEElKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDM--DRKK 404
Cdd:TIGR00606 716 SELKK-KEKRRDEMLGLAPGRQ-SIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCltDVTI 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 405 IEELMEENMTLE--MAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVnELTSSRLLKLEMENQSLTKTVEELRTT 482
Cdd:TIGR00606 794 MERFQMELKDVErkIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKI-ELNRKLIQDQQEQIQHLKSKTNELKSE 872
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 483 VDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEH 562
Cdd:TIGR00606 873 KLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKN 952
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 563 LNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEE------LENELHH 636
Cdd:TIGR00606 953 IHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERWLQDnltlrkRENELKE 1032
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 637 LEKENELLQKKITNLKITCEKIEALEQENsELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLElrrnvESLKCA 716
Cdd:TIGR00606 1033 VEEELKQHLKEMGQMQVLQMKQEHQKLEE-NIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAE-----EKYREM 1106
|
490 500
....*....|....*....|....*
gi 208022632 717 SMKMAQLQLENKELESEKEQLKKGL 741
Cdd:TIGR00606 1107 MIVMRTTELVNKDLDIYYKTLDQAI 1131
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
507-769 |
2.22e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 42.99 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 507 VEIleNEIVQEKQSLQNcQNLSKDLMKekaqLEKTIETLRENSERQIKILEQENEhlnQTVSSLRQRSQiSAEARVKDIE 586
Cdd:PRK05771 31 VHI--EDLKEELSNERL-RKLRSLLTK----LSEALDKLRSYLPKLNPLREEKKK---VSVKSLEELIK-DVEEELEKIE 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 587 KENKILHESIKETSSKLSKIEFEKRQIKKelehykekgeraeeleneLHHLEKENELLQKKiTNLKITCEKIEALEQENS 666
Cdd:PRK05771 100 KEIKELEEEISELENEIKELEQEIERLEP------------------WGNFDLDLSLLLGF-KYVSVFVGTVPEDKLEEL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 667 ELERENRKLkKTLDSFKNLTF--------QLESLEKENSQLDEENLELrrnvESLKCASMKMAQLQLENKELESEKEQLK 738
Cdd:PRK05771 161 KLESDVENV-EYISTDKGYVYvvvvvlkeLSDEVEEELKKLGFERLEL----EEEGTPSELIREIKEELEEIEKERESLL 235
|
250 260 270
....*....|....*....|....*....|..
gi 208022632 739 KGLELLKasfKKTERLEVSYQG-LDIENQRLQ 769
Cdd:PRK05771 236 EELKELA---KKYLEELLALYEyLEIELERAE 264
|
|
| FPP |
pfam05911 |
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant ... |
769-887 |
2.44e-03 |
|
Filament-like plant protein, long coiled-coil; FPP is a family of long coiled-coil plant proteins that are filament-like. It interacts with the nuclear envelope-associated protein, MAF1, the WPP family pfam13943.
Pssm-ID: 461778 [Multi-domain] Cd Length: 859 Bit Score: 42.74 E-value: 2.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 769 QKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKIsskRLEQLEKENKSLEQETSQLEKDKKQLEKE-------NKRL 841
Cdd:pfam05911 680 TEENKRLKEEFEQLKSEKENLEVELASCTENLESTKS---QLQESEQLIAELRSELASLKESNSLAETQlkcmaesYEDL 756
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 208022632 842 RQQAEIKDTTLEENNVKIGNLEKEnktLSKEIGIYKESCVRLKELE 887
Cdd:pfam05911 757 ETRLTELEAELNELRQKFEALEVE---LEEEKNCHEELEAKCLELQ 799
|
|
| Prefoldin_2 |
pfam01920 |
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996. |
777-854 |
2.45e-03 |
|
Prefoldin subunit; This family includes prefoldin subunits that are not detected by pfam02996.
Pssm-ID: 396482 [Multi-domain] Cd Length: 102 Bit Score: 39.13 E-value: 2.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 777 KKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENK------------SLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam01920 2 NKFQQLQQQLQLLAQQIKQLETQLKELELALEELELLDEDTKvykligdvlvkqDKEEVKEQLEERKETLEKEIKTLEKQ 81
|
90
....*....|
gi 208022632 845 AEIKDTTLEE 854
Cdd:pfam01920 82 LEKLEKELEE 91
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
619-938 |
2.60e-03 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 42.97 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 619 HYKEKGERAEELENELhhLEKENELLQKKITNLKITCEKIEALEQENseLERENRKLKKTLDSFKNLTFQLESLekensq 698
Cdd:PLN02939 64 KLQSNTDENGQLENTS--LRTVMELPQKSTSSDDDHNRASMQRDEAI--AAIDNEQQTNSKDGEQLSDFQLEDL------ 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 699 ldeenLELRRNVES--LKCASMKMAQLQLENKELeSEKEQLKKGLELLKASFKKT-ERLEVSYQGlDIENQRLQKTLENS 775
Cdd:PLN02939 134 -----VGMIQNAEKniLLLNQARLQALEDLEKIL-TEKEALQGKINILEMRLSETdARIKLAAQE-KIHVEILEEQLEKL 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 776 NKKIQQ-----------LESELQDLEMEN-------QTLQKNLEELKISSKRLEQLEKENKSLEQETSQLE-------KD 830
Cdd:PLN02939 207 RNELLIrgateglcvhsLSKELDVLKEENmllkddiQFLKAELIEVAETEERVFKLEKERSLLDASLRELEskfivaqED 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 831 KKQL---------EK-EN-----KRLRQQAEIKDTTLEENNVKIGNLEKENKTLsKEIGIYKESCVRLKELEKENK---E 892
Cdd:PLN02939 287 VSKLsplqydcwwEKvENlqdllDRATNQVEKAALVLDQNQDLRDKVDKLEASL-KEANVSKFSSYKVELLQQKLKlleE 365
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 208022632 893 LVKRATIDIKTLVTLREDLVSEklktqqMNNDLEKLTHELEKIGLN 938
Cdd:PLN02939 366 RLQASDHEIHSYIQLYQESIKE------FQDTLSKLKEESKKRSLE 405
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
305-512 |
2.76e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.70 E-value: 2.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 305 ARMYRDELDALREKAVR--VDKLESEVSRYKERLHDIEfykARVEELKEDNQVLL--ETKTMLEDQLEGTRARsdkLHEL 380
Cdd:COG3206 158 AEAYLEQNLELRREEARkaLEFLEEQLPELRKELEEAE---AALEEFRQKNGLVDlsEEAKLLLQQLSELESQ---LAEA 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 381 EKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESlhlgwELEQISRTSeLSEAPQ--------KSLGH 452
Cdd:COG3206 232 RAELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEA-----ELAELSARY-TPNHPDvialraqiAALRA 305
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 453 EVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILEN 512
Cdd:COG3206 306 QLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARE 365
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
495-605 |
2.83e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.46 E-value: 2.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 495 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQ-----ENEHLNQTVSS 569
Cdd:PRK12704 83 ELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERisgltAEEAKEILLEK 162
|
90 100 110
....*....|....*....|....*....|....*.
gi 208022632 570 LRQRSQISAEARVKDIEKEnkilhesIKETSSKLSK 605
Cdd:PRK12704 163 VEEEARHEAAVLIKEIEEE-------AKEEADKKAK 191
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
778-1379 |
2.90e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 42.73 E-value: 2.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 778 KIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEEnnv 857
Cdd:TIGR00606 225 QITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE--- 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 858 KIGNLEKENKTLSKEIGIYKESCVRlkELEKENKELVKRATIDIKTLVTL-REDLVSEKLKTQQMNNDLEKLTHELEKIG 936
Cdd:TIGR00606 302 QLNDLYHNHQRTVREKERELVDCQR--ELEKLNKERRLLNQEKTELLVEQgRLQLQADRHQEHIRARDSLIQSLATRLEL 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 937 LNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMV 1016
Cdd:TIGR00606 380 DGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFV 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1017 QSSppisgednkwERESQETTRELLKVKDRLIEVERNNAtlQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQ- 1095
Cdd:TIGR00606 460 IKE----------LQQLEGSSDRILELDQELRKAERELS--KAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQl 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1096 --NTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQS----SLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQ 1169
Cdd:TIGR00606 528 nhHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLgyfpNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNK 607
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1170 ASEYESLISKHGTLKSAHKNLeVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRL 1249
Cdd:TIGR00606 608 NHINNELESKEEQLSSYEDKL-FDVCGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRV 686
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1250 NHTYSQllketevLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQ 1329
Cdd:TIGR00606 687 FQTEAE-------LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|...
gi 208022632 1330 IQTL---MLQNRTLLEQNMESKDLFHVEQRQyIDKLNELRRQKEKLEEKIMDQ 1379
Cdd:TIGR00606 760 IQRLkndIEEQETLLGTIMPEEESAKVCLTD-VTIMERFQMELKDVERKIAQQ 811
|
|
| PRK12705 |
PRK12705 |
hypothetical protein; Provisional |
566-742 |
3.16e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 237178 [Multi-domain] Cd Length: 508 Bit Score: 42.39 E-value: 3.16e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 566 TVSSLRQRSQISAEARvkdiekenKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERA--EELENELHHLEKENEL 643
Cdd:PRK12705 21 LVVLLKKRQRLAKEAE--------RILQEAQKEAEEKLEAALLEAKELLLRERNQQRQEARRerEELQREEERLVQKEEQ 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 644 LQKKitnlkitCEKIEALEQEnseLERENRKLKKtldsfknltfQLESLEKENSQLDEENLElrrnVESLKCASMKMAQL 723
Cdd:PRK12705 93 LDAR-------AEKLDNLENQ---LEEREKALSA----------RELELEELEKQLDNELYR----VAGLTPEQARKLLL 148
|
170
....*....|....*....
gi 208022632 724 QLENKELESEKEQLKKGLE 742
Cdd:PRK12705 149 KLLDAELEEEKAQRVKKIE 167
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
734-1014 |
3.24e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.81 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 734 KEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLemeNQTLQKNLEELKISSKRLEQL 813
Cdd:COG4372 30 SEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL---NEQLQAAQAELAQAQEELESL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 814 EKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKElEKENKEL 893
Cdd:COG4372 107 QEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSE-AEAEQAL 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 894 VKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEE 973
Cdd:COG4372 186 DELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELEL 265
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 208022632 974 KIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEER 1014
Cdd:COG4372 266 AILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAA 306
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
257-605 |
3.35e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 42.53 E-value: 3.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 257 KAKIRRLRQELEEKTEQLLDCKQE--------LEQMeieLKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLEse 328
Cdd:PLN03229 428 KTPVRELEGEVEKLKEQILKAKESsskpselaLNEM---IEKLKKEIDLEYTEAVIAMGLQERLENLREEFSKANSQD-- 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 329 vsrykERLHDIefYKARVEELKEDNQVLLETKTmledQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDrKKIEEL 408
Cdd:PLN03229 503 -----QLMHPV--LMEKIEKLKDEFNKRLSRAP----NYLSLKYKLDMLNEFSRAKALSEKKSKAEKLKAEIN-KKFKEV 570
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 409 MEENmtlEMAQKqsmdeslhlgweLEQISRTSELSEApqkSLGHEVNELTSSRLLKLEMENQ-SLTKTVEELRTTVDSVE 487
Cdd:PLN03229 571 MDRP---EIKEK------------MEALKAEVASSGA---SSGDELDDDLKEKVEKMKKEIElELAGVLKSMGLEVIGVT 632
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 488 GNAsKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQEnehLNQTV 567
Cdd:PLN03229 633 KKN-KDTAEQTPPPNLQEKIESLNEEINKKIERVIRSSDLKSKIELLKLEVAKASKTPDVTEKEKIEALEQQ---IKQKI 708
|
330 340 350
....*....|....*....|....*....|....*...
gi 208022632 568 SSLRQRSQIsaEARVKDIEKENKILHESIKETSSKLSK 605
Cdd:PLN03229 709 AEALNSSEL--KEKFEELEAELAAARETAAESNGSLKN 744
|
|
| ClpA |
COG0542 |
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
578-702 |
3.36e-03 |
|
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 42.38 E-value: 3.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 578 AEARVKdIEKENKIlhESIKETSSKLSKIEFEKRQIKKELEHYKEkgERAEELENELHHLEKENELLQKKITNLKITCEK 657
Cdd:COG0542 398 AAARVR-MEIDSKP--EELDELERRLEQLEIEKEALKKEQDEASF--ERLAELRDELAELEEELEALKARWEAEKELIEE 472
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 208022632 658 IEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKEnsQLDEE 702
Cdd:COG0542 473 IQELKEELEQRYGKIPELEKELAELEEELAELAPLLRE--EVTEE 515
|
|
| PTZ00341 |
PTZ00341 |
Ring-infected erythrocyte surface antigen; Provisional |
375-1039 |
3.38e-03 |
|
Ring-infected erythrocyte surface antigen; Provisional
Pssm-ID: 173534 [Multi-domain] Cd Length: 1136 Bit Score: 42.47 E-value: 3.38e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 375 DKLHELEKEN-LQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHE 453
Cdd:PTZ00341 414 DLLFDLEKQKyMDMLDGSEDESVEDNEEEHSGDANEEELSVDEHVEEHNADDSGEQQSDDESGEHQSVNEIVEEQSVNEH 493
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 454 VNELTSSRLLKLEMENQSLTKTV----EELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQ---SLQNCQN 526
Cdd:PTZ00341 494 VEEPTVADIVEQETVDEHVEEPAvdenEEQQTADEHVEEPTIAEEHVEEEISTAEEHIEEPASDVQQDSEaapTIEIPDT 573
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 527 LSKDLMKEKAQLEktietLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARV-KDIEKE---NKILHESIKETS-- 600
Cdd:PTZ00341 574 LFYDILGVGVNAD-----MKEISERYFKLAENYYPPKRSGNEGFHKFKKINEAYQIlGDIDKKkmyNKFGYDGIKGVNfi 648
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 601 --------SKLSKIEF--EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKiTNLKITCEKIEALEQENSELER 670
Cdd:PTZ00341 649 hpsifyllASLEKFADftGSPQIVTLLKFFFEKKLSMNDLDNKSEHLLKFMEQYQKE-REAHISENLINILQPCIAGDRK 727
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 671 ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVeslKCASMKMAQLQLENKE-LESEKEQLkkgLELLKASFK 749
Cdd:PTZ00341 728 WDVPIIDKIEELKGSPFDIAIIDSIGWIFKHVAKSHLKKP---KKAAKKLEQRSKANKEeLANENNKL---MNILKEYFG 801
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 750 KTERLE-----VSYQGLDIENQRLQKTLENSNKKIQQ----------LESELQDLE-----MENQTLQKNLEELKISSKR 809
Cdd:PTZ00341 802 NNEQINsitynFENINLNEDNENGSKKILDLNHKDQKeifeeiisyiVDISLSDIEntaknAAEQILSDEGLDEKKLKKR 881
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 810 LEQLEKENKSLEQETSQLEKDKKQLEKE---------------NKRLRQQAEIKDTTLEEN-NVKIGNLEKENKTLSKEI 873
Cdd:PTZ00341 882 AESLKKLANAIEKYAGGGKKDKKAKKKDakdlsgniaheinliNKELKNQNENVPEHLKEHaEANIEEDAEENVEEDAEE 961
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDL-------VSEKLKTQQMNNDLEKLTHELEKIGLNKERllHDE 946
Cdd:PTZ00341 962 NVEENVEENVEENVEENVEENVEENVEENVEENVEENVeenieenVEENVEENIEENVEEYDEENVEEVEENVEE--YDE 1039
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 947 QSTDDRYKLLESKLESTLKKSLE-IKEEKIAALEARLEESTNYNQQlrqelKTVKKNYEALKQRQDE--ERMVQSSPPIS 1023
Cdd:PTZ00341 1040 ENVEEIEENAEENVEENIEENIEeYDEENVEEIEENIEENIEENVE-----ENVEENVEEIEENVEEnvEENAEENAEEN 1114
|
730
....*....|....*.
gi 208022632 1024 GEDNKwERESQETTRE 1039
Cdd:PTZ00341 1115 AEENA-EEYDDENPEE 1129
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
262-854 |
3.45e-03 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 42.43 E-value: 3.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 262 RLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELdALREKAVRvdkleSEVSRYKERLHDIEF 341
Cdd:pfam07111 56 EGSQALSQQAELISRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELDAL-AVAEKAGQ-----AEAEGLRAALAGAEM 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 342 YKARVEELKEdnQVLLETKTMLEDQLEG-TRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK 420
Cdd:pfam07111 130 VRKNLEEGSQ--RELEEIQRLHQEQLSSlTQAHEEALSSLTSKAEGLEKSLNSLETKRAGEAKQLAEAQKEAELLRKQLS 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 421 QSMDE---SLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSrLLKLEMENQSLTKTVEELRTTVDSVegnaSKILKME 497
Cdd:pfam07111 208 KTQEEleaQVTLVESLRKYVGEQVPPEVHSQTWELERQELLDT-MQHLQEDRADLQATVELLQVRVQSL----THMLALQ 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 498 KEnqRLSKKVEILEneiVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQIS 577
Cdd:pfam07111 283 EE--ELTRKIQPSD---SLEPEFPKKCRSLLNRWREKVFALMVQLKAQDLEHRDSVKQLRGQVAELQEQVTSQSQEQAIL 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 578 AEArVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEkgeraeELENELHHLEKENELLQKKITNLKITCEK 657
Cdd:pfam07111 358 QRA-LQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTASAEE------QLKFVVNAMSSTQIWLETTMTRVEQAVAR 430
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 658 IEALeqeNSELERENRKLKkTLDSFKNLTFQLESLEKENSQLDEENLELRRNVeslkcaSMKMAQLQLENKELESEKEql 737
Cdd:pfam07111 431 IPSL---SNRLSYAVRKVH-TIKGLMARKVALAQLRQESCPPPPPAPPVDADL------SLELEQLREERNRLDAELQ-- 498
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 738 kkglelLKASFKKTERLEVSYQGlDIENQRLqktlensNKKIQQLESELQDLEmenQTLQKNLEELKISSKRLEQLEKEN 817
Cdd:pfam07111 499 ------LSAHLIQQEVGRAREQG-EAERQQL-------SEVAQQLEQELQRAQ---ESLASVGQQLEVARQGQQESTEEA 561
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 208022632 818 KSLEQETSQLEKDKKQLEKEN-----KRLRQQAEIKDTTLEE 854
Cdd:pfam07111 562 ASLRQELTQQQEIYGQALQEKvaeveTRLREQLSDTKRRLNE 603
|
|
| mukB |
PRK04863 |
chromosome partition protein MukB; |
535-846 |
3.49e-03 |
|
chromosome partition protein MukB;
Pssm-ID: 235316 [Multi-domain] Cd Length: 1486 Bit Score: 42.64 E-value: 3.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 535 KAQLEKTIETLRENSERQIKiLEQENEHLNQTVSSLrqrsqiSAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIK 614
Cdd:PRK04863 792 RAEREELAERYATLSFDVQK-LQRLHQAFSRFIGSH------LAVAFEADPEAELRQLNRRRVELERALADHESQEQQQR 864
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 615 KELEHYKEK-------------------GERAEELENELHHLEKEN----------ELLQKKITNLKITCEKIEALEQEN 665
Cdd:PRK04863 865 SQLEQAKEGlsalnrllprlnlladetlADRVEEIREQLDEAEEAKrfvqqhgnalAQLEPIVSVLQSDPEQFEQLKQDY 944
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQ-LDEENLELrrnVESLKcasmkmAQLqlenKELESEKEQLKKGLELL 744
Cdd:PRK04863 945 QQAQQTQRDAKQQAFALTEVVQRRAHFSYEDAAeMLAKNSDL---NEKLR------QRL----EQAEQERTRAREQLRQA 1011
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 745 KASFkkTERLEVsYQGLDIENQRLQKTLensnkkiQQLESELQDL------EMENQ------TLQKNLEElkiSSKRLEQ 812
Cdd:PRK04863 1012 QAQL--AQYNQV-LASLKSSYDAKRQML-------QELKQELQDLgvpadsGAEERararrdELHARLSA---NRSRRNQ 1078
|
330 340 350
....*....|....*....|....*....|....
gi 208022632 813 LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAE 846
Cdd:PRK04863 1079 LEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVV 1112
|
|
| TOPEUc |
smart00435 |
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ... |
770-855 |
3.66e-03 |
|
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras
Pssm-ID: 214661 [Multi-domain] Cd Length: 391 Bit Score: 41.95 E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 770 KTLENSNKKIQQLESELQDLEMENQTLQKNL---EELKISSKRL-EQLEKENKSLEQETSQLEKDKKQLEKENKRLrQQA 845
Cdd:smart00435 277 KSMEKLQEKIKALKYQLKRLKKMILLFEMISdlkRKLKSKFERDnEKLDAEVKEKKKEKKKEEKKKKQIERLEERI-EKL 355
|
90
....*....|
gi 208022632 846 EIKDTTLEEN 855
Cdd:smart00435 356 EVQATDKEEN 365
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
183-345 |
4.25e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 4.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 183 QEDIEPLLKNMALHLKRLIDERDEHSETIIEL--SEERDGLHFLPHASSSAQSPCGSPGMKR-TESRQHLSVELADAKAK 259
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQKEELAELLRALyrLGRQPPLALLLSPEDFLDAVRRLQYLKYlAPARREQAEELRADLAE 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 260 IRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARM-YRDELDALREKAVR----VDKLESEVSRYKE 334
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAeLAAELAELQQEAEElealIARLEAEAAAAAE 241
|
170
....*....|.
gi 208022632 335 RLHDIEFYKAR 345
Cdd:COG4942 242 RTPAAGFAALK 252
|
|
| PLN03229 |
PLN03229 |
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional |
652-1027 |
4.67e-03 |
|
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
Pssm-ID: 178768 [Multi-domain] Cd Length: 762 Bit Score: 41.76 E-value: 4.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 652 KITCEKIEALEQENSELERENRKLKKTLdsfknltfqlesLEKENSQLDEENLELRRNVESLKcasmkmAQLQLENKElE 731
Cdd:PLN03229 418 KVNMKKREAVKTPVRELEGEVEKLKEQI------------LKAKESSSKPSELALNEMIEKLK------KEIDLEYTE-A 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 732 SEKEQLKKGLELLKASFKKTerlevsyqglDIENQRLQKTLENSNKKIQQlESELQDLEMENQT-LQKNLEELKISSKRL 810
Cdd:PLN03229 479 VIAMGLQERLENLREEFSKA----------NSQDQLMHPVLMEKIEKLKD-EFNKRLSRAPNYLsLKYKLDMLNEFSRAK 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 811 EQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAeIKDTTLEENNVKIGNLEKEnktlskeigiYKESCVRLK-ELEKE 889
Cdd:PLN03229 548 ALSEKKSKAEKLKAEINKKFKEVMDRPEIKEKMEA-LKAEVASSGASSGDELDDD----------LKEKVEKMKkEIELE 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 890 NKELVKRATIDIkTLVTLREDLVSEKLKTQQMNNDLEKLThelEKIGLNKERLLhdeQSTDDRYKLLESKLESTL--KKS 967
Cdd:PLN03229 617 LAGVLKSMGLEV-IGVTKKNKDTAEQTPPPNLQEKIESLN---EEINKKIERVI---RSSDLKSKIELLKLEVAKasKTP 689
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 208022632 968 LEIKEEKIAALEarleestnynQQLRQELKTVkKNYEALKQRQDE-ERMVQSSPPISGEDN 1027
Cdd:PLN03229 690 DVTEKEKIEALE----------QQIKQKIAEA-LNSSELKEKFEElEAELAAARETAAESN 739
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
1147-1376 |
4.73e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 4.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1147 DLKSLyDSLIKDHekleLLHERQASE-YESLISKHGTLKSAHKNLE-----VEH----RDLEDRYNQLLKQKGQLEDLEK 1216
Cdd:COG4913 205 PIGDL-DDFVREY----MLEEPDTFEaADALVEHFDDLERAHEALEdareqIELlepiRELAERYAAARERLAELEYLRA 279
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1217 MLKVEQEKMLLENKNHETVAAEykklcGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQ-TRLEAEFSKLKEQY 1295
Cdd:COG4913 280 ALRLWFAQRRLELLEAELEELR-----AELARLEAELERLEARLDALREELDELEAQIRGNGGDRlEQLEREIERLEREL 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1296 QQLditSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLmlqnRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEK 1375
Cdd:COG4913 355 EER---ERRRARLEALLAALGLPLPASAEEFAALRAEA----AALLEALEEELEALEEALAEAEAALRDLRRELRELEAE 427
|
.
gi 208022632 1376 I 1376
Cdd:COG4913 428 I 428
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1207-1375 |
4.80e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.29 E-value: 4.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1207 QKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEA 1286
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1287 EFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELR 1366
Cdd:COG4942 98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177
|
....*....
gi 208022632 1367 RQKEKLEEK 1375
Cdd:COG4942 178 ALLAELEEE 186
|
|
| Tektin |
pfam03148 |
Tektin family; Tektins are cytoskeletal proteins. They have been demonstrated in such cellular ... |
540-815 |
5.41e-03 |
|
Tektin family; Tektins are cytoskeletal proteins. They have been demonstrated in such cellular sites as centrioles, basal bodies, and along ciliary and flagellar doublet microtubules. Tektins form unique protofilaments, organized as longitudinal polymers of tektin heterodimers with axial periodicity matching tubulin. Tektin polypeptides consist of several alpha-helical regions that are predicted to form coiled coils. Indeed, tektins share considerable structural similarities with intermediate filament proteins. Possible functional roles for tektins are: stabilization of tubulin protofilaments; attachment of A and B-tubules in ciliary/flagellar microtubule doublets and C-tubules in centrioles; binding of axonemal components.
Pssm-ID: 460827 [Multi-domain] Cd Length: 383 Bit Score: 41.38 E-value: 5.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 540 KTIETLRENSERqikiLEQENEHLNQTVSSLRQRSQISA----EARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKK 615
Cdd:pfam03148 10 REAEAQRNDAER----LRQESRRLRNETDAKTKWDQYDSnrrlGERIQDITFWKSELEKELEELDEEIELLLEEKRRLEK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 616 ELEHYKEKGERAEE--------LENEL------HHLEKENELLQKKITNLKITCEKIEaleqensELERENRKLKKTLDs 681
Cdd:pfam03148 86 ALEALEEPLHIAQEcltlrekrQGIDLvhdeveKELLKEVELIEGIQELLQRTLEQAW-------EQLRLLRAARHKLE- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 682 fKNLTFQLESLEkensqLDEENLELRRNVE--SLKCASMKMAQLQLENKE-LESEKEQLKKGLELLKASFKKTERLEVSY 758
Cdd:pfam03148 158 -KDLSDKKEALE-----IDEKCLSLNNTSPniSYKPGPTRIPPNSSTPEEwEKFTQDNIERAEKERAASAQLRELIDSIL 231
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 208022632 759 QGL--DIENQRlQKTLENSNKKIQQLESELQDLEMEnqtLQKNLEELKISSKRLEQLEK 815
Cdd:pfam03148 232 EQTanDLRAQA-DAVNFALRKRIEETEDAKNKLEWQ---LKKTLQEIAELEKNIEALEK 286
|
|
| CCDC22 |
pfam05667 |
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 ... |
485-840 |
5.47e-03 |
|
Coiled-coil domain-containing protein 22; Human coiled-coil domain-containing protein 22 (CCDC22) is involved in regulation of NF-kappa-B signalling; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. It is part of the OMMD/CCDC22/CCDC93 (CCC) complex, which interacts with the multisubunit WASH complex required for endosomal deposition of F-actin and cargo trafficking in conjunction with the retromer. This entry also includes CCDC22 homologs from animals and plants.
Pssm-ID: 461708 [Multi-domain] Cd Length: 600 Bit Score: 41.55 E-value: 5.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 485 SVEGNASKILKMEKENQRLSKKVEILENEIVQE-KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQikileqenehl 563
Cdd:pfam05667 223 EEEWNSQGLASRLTPEEYRKRKRTKLLKRIAEQlRSAALAGTEATSGASRSAQDLAELLSSFSGSSTTD----------- 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 564 nqtvsslRQRSQISAEARVKDIEKENkilhESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENEL 643
Cdd:pfam05667 292 -------TGLTKGSRFTHTEKLQFTN----EAPAATSSPPTKVETEEELQQQREEELEELQEQLEDLESSIQELEKEIKK 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 644 LQKKITNLKitcEKIEALEQENSELERENRKLKKTLDSFKNltfqleslekensqlDEENLElrrnveslkcasmkmaql 723
Cdd:pfam05667 361 LESSIKQVE---EELEELKEQNEELEKQYKVKKKTLDLLPD---------------AEENIA------------------ 404
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 724 qlenkELESEKEQLKKGLELLKASFKKterlevsYQGLDIEnqrlqktlensnkKIQQLESELQDLEMENqtlQKNLEEL 803
Cdd:pfam05667 405 -----KLQALVDASAQRLVELAGQWEK-------HRVPLIE-------------EYRALKEAKSNKEDES---QRKLEEI 456
|
330 340 350
....*....|....*....|....*....|....*..
gi 208022632 804 KISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Cdd:pfam05667 457 KELREKIKEVAEEAKQKEELYKQLVAEYERLPKDVSR 493
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
625-683 |
5.80e-03 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 41.36 E-value: 5.80e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 208022632 625 ERAEELENELHHLEKENELLQkkitnlkitcEKIEALEQENSELERENRKLKKTLDSFK 683
Cdd:PRK03992 1 ERLEALEERNSELEEQIRQLE----------LKLRDLEAENEKLERELERLKSELEKLK 49
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
675-894 |
6.51e-03 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 41.44 E-value: 6.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 675 LKKTLDSFKNLTFQ---LESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELesekEQLKKGLELLKASFKKT 751
Cdd:PRK11281 65 LEQTLALLDKIDRQkeeTEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSL----RQLESRLAQTLDQLQNA 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 752 ERLEVSYQGLDIENQ----RLQKTLENSNKKIQQLESELQDLEMENQTLqknleelkiSSKRLEQLEKENKSLEQETSQl 827
Cdd:PRK11281 141 QNDLAEYNSQLVSLQtqpeRAQAALYANSQRLQQIRNLLKGGKVGGKAL---------RPSQRVLLQAEQALLNAQNDL- 210
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 208022632 828 ekdKKQLEKENKRLRQQAEIKdttLEENNVKIGNLEKENKTLSKEIgiykeSCVRLKELEKENKELV 894
Cdd:PRK11281 211 ---QRKSLEGNTQLQDLLQKQ---RDYLTARIQRLEHQLQLLQEAI-----NSKRLTLSEKTVQEAQ 266
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
342-984 |
6.65e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 41.35 E-value: 6.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 342 YKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELeKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQ 421
Cdd:pfam10174 125 HERQAKELFLLRKTLEEMELRIETQKQTLGARDESIKKL-LEMLQSKGLPKKSGEEDWERTRRIAEAEMQLGHLEVLLDQ 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 422 SMDESLHLGwelEQISRTSELSEAPQKSLG-HEVNELTSSRLLKLEMENQSLTKTVEELRTTVD-SVEGNASKILKME-- 497
Cdd:pfam10174 204 KEKENIHLR---EELHRRNQLQPDPAKTKAlQTVIEMKDTKISSLERNIRDLEDEVQMLKTNGLlHTEDREEEIKQMEvy 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 498 KENQRLSK-KVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENserqIKILEQENEHLNQTVSSLRQRsqi 576
Cdd:pfam10174 281 KSHSKFMKnKIDQLKQELSKKESELLALQTKLETLTNQNSDCKQHIEVLKES----LTAKEQRAAILQTEVDALRLR--- 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 577 sAEARVKDIEKENKILHESIKETSS--------------KLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENE 642
Cdd:pfam10174 354 -LEEKESFLNKKTKQLQDLTEEKSTlageirdlkdmldvKERKINVLQKKIENLQEQLRDKDKQLAGLKERVKSLQTDSS 432
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 643 LLQKKITNLK-ITCEKIEALEQENSELERENRKLKKTLDSF----KNLTFQLESLEKENSQLDEENLELRRNVESLKCAS 717
Cdd:pfam10174 433 NTDTALTTLEeALSEKERIIERLKEQREREDRERLEELESLkkenKDLKEKVSALQPELTEKESSLIDLKEHASSLASSG 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 718 MKMAQlqlENKELESEKEQLKKGLELLKASFKKTERLEVSyqgldienqrlQKTLENSNKKIQQLESELQDLEMENQTLQ 797
Cdd:pfam10174 513 LKKDS---KLKSLEIAVEQKKEECSKLENQLKKAHNAEEA-----------VRTNPEINDRIRLLEQEVARYKEESGKAQ 578
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 798 KNLEELkisskrLEQLEkenkslEQETSQLEKDKKQLEKENKRLRQqaeIKDTTLEENNVKIGNLEKENKtlskeigiyk 877
Cdd:pfam10174 579 AEVERL------LGILR------EVENEKNDKDKKIAELESLTLRQ---MKEQNKKVANIKHGQQEMKKK---------- 633
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 878 escvRLKELEKENKELVKRATidiktlvtlredlVSEKLKTQQMNNDLEKLTHELEKIGLnkeRLLHDEQSTDDRYKLLE 957
Cdd:pfam10174 634 ----GAQLLEEARRREDNLAD-------------NSQQLQLEELMGALEKTRQELDATKA---RLSSTQQSLAEKDGHLT 693
|
650 660
....*....|....*....|....*..
gi 208022632 958 SKLESTLKKSLEIKEEKIAALEARLEE 984
Cdd:pfam10174 694 NLRAERRKQLEEILEMKQEALLAAISE 720
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
1134-1356 |
7.04e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 41.03 E-value: 7.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1134 LENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGqlED 1213
Cdd:pfam07888 50 QEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRA--AH 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1214 LEKMLKVEQEKMLLENKNHETVAaeykklcgENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKE 1293
Cdd:pfam07888 128 EARIRELEEDIKTLTQRVLERET--------ELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRN 199
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 208022632 1294 QYQQLDITSTKLNNQCELLSQlkgnleeenrhLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR 1356
Cdd:pfam07888 200 SLAQRDTQVLQLQDTITTLTQ-----------KLTTAHRKEAENEALLEELRSLQERLNASER 251
|
|
| KpsE |
COG3524 |
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis]; |
1055-1136 |
7.11e-03 |
|
Capsule polysaccharide export protein KpsE/RkpR [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442746 [Multi-domain] Cd Length: 370 Bit Score: 40.99 E-value: 7.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1055 ATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQnttLQTQNAKL--QVENSTLNSQST-----SLMNQNAQL 1127
Cdd:COG3524 224 ATLEGQLAELEAELAALRSYLSPNSPQVRQLRRRIAALEKQ---IAAERARLtgASGGDSLASLLAeyerlELEREFAEK 300
|
90
....*....|.
gi 208022632 1128 LIQQS--SLEN 1136
Cdd:COG3524 301 AYTSAlaALEQ 311
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
784-820 |
7.13e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 7.13e-03
10 20 30
....*....|....*....|....*....|....*..
gi 208022632 784 SELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSL 820
Cdd:PRK13922 69 ASLFDLREENEELKKELLELESRLQELEQLEAENARL 105
|
|
| GAS |
pfam13851 |
Growth-arrest specific micro-tubule binding; This family is the highly conserved central ... |
736-844 |
7.30e-03 |
|
Growth-arrest specific micro-tubule binding; This family is the highly conserved central region of a number of metazoan proteins referred to as growth-arrest proteins. In mouse, Gas8 is predominantly a testicular protein, whose expression is developmentally regulated during puberty and spermatogenesis. In humans, it is absent in infertile males who lack the ability to generate gametes. The localization of Gas8 in the motility apparatus of post-meiotic gametocytes and mature spermatozoa, together with the detection of Gas8 also in cilia at the apical surfaces of epithelial cells lining the pulmonary bronchi and Fallopian tubes suggests that the Gas8 protein may have a role in the functioning of motile cellular appendages. Gas8 is a microtubule-binding protein localized to regions of dynein regulation in mammalian cells.
Pssm-ID: 464001 [Multi-domain] Cd Length: 200 Bit Score: 39.89 E-value: 7.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 736 QLKKGLELLKASFKKTERLevsYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKnleelkiSSKRLEQLEK 815
Cdd:pfam13851 30 SLKEEIAELKKKEERNEKL---MSEIQQENKRLTEPLQKAQEEVEELRKQLENYEKDKQSLKN-------LKARLKVLEK 99
|
90 100
....*....|....*....|....*....
gi 208022632 816 ENKSLEQETSQLEKDKKQLEKENKRLRQQ 844
Cdd:pfam13851 100 ELKDLKWEHEVLEQRFEKVERERDELYDK 128
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
608-732 |
7.61e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.92 E-value: 7.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 608 FEKRQIKKELEHYKEKGER-AEELENELHHLEKENEL-LQKKITNLKITCEKieALEQENSELERENRKLKKTLDSFKNl 685
Cdd:PRK12704 24 VRKKIAEAKIKEAEEEAKRiLEEAKKEAEAIKKEALLeAKEEIHKLRNEFEK--ELRERRNELQKLEKRLLQKEENLDR- 100
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 208022632 686 tfQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE-NKELES 732
Cdd:PRK12704 101 --KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEqLQELER 146
|
|
| Prominin |
pfam05478 |
Prominin; The prominins are an emerging family of proteins that among the multispan membrane ... |
635-873 |
7.78e-03 |
|
Prominin; The prominins are an emerging family of proteins that among the multispan membrane proteins display a novel topology. Mouse prominin and human prominin (mouse)-like 1 (PROML1) are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. The exact function of prominin is unknown although in humans defects in PROM1, the gene coding for prominin, cause retinal degeneration.
Pssm-ID: 461660 [Multi-domain] Cd Length: 799 Bit Score: 41.07 E-value: 7.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 635 HHLEKENELLQKKI----TNLKITCEKIEALEQEN-SELERenrKLKKTLDSFKNLTF-----QLESleKENSQLDEenl 704
Cdd:pfam05478 169 RGIGESTETMRRGLrdlrTFLSDVPQHIDHVLVQNySELQD---HVSDDLDDAGKHIGldihdTLES--NVYPALAE--- 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 705 eLRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKasfkktERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Cdd:pfam05478 241 -LERILQNMPEAKDLLEQVNALLKDLRFYGTQLRDGLRGVK------RDLNYALSNPLCTTQECDKFLSSLSIEFLDTSA 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 785 EL-----QDLEMEN--QTLQKNLEelKISSKRLEQLEKENKSLEQETSQLEKD-KKQLEKENKRLRQQAE-IKDTTLEEN 855
Cdd:pfam05478 314 CLdqlpnVDEFLENvkGVIETNLS--SIVQEGLDRFNNIPEKVKNQTAGVVPPlKRALAQIREQIRTLATdIPRDALSAV 391
|
250
....*....|....*...
gi 208022632 856 NVKIGNLEKENKTLSKEI 873
Cdd:pfam05478 392 SSDIHNTERSSRTFLDVV 409
|
|
| ATG16 |
pfam08614 |
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for ... |
531-675 |
7.86e-03 |
|
Autophagy protein 16 (ATG16); Autophagy is a ubiquitous intracellular degradation system for eukaryotic cells. During autophagy, cytoplasmic components are enclosed in autophagosomes and delivered to lysosomes/vacuoles. ATG16 (also known as Apg16) has been shown to be bind to Apg5 and is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
Pssm-ID: 462536 [Multi-domain] Cd Length: 176 Bit Score: 39.14 E-value: 7.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 531 LMKEKAQLEKTIETLRENSERQIKILEQENEH----LNQTVSSLR------QRSQISAEARVKDIEKENKILHESIKETS 600
Cdd:pfam08614 19 LEAENAKLQSEPESVLPSTSSSKLSKASPQSAsiqsLEQLLAQLReelaelYRSRGELAQRLVDLNEELQELEKKLREDE 98
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 208022632 601 SKLSKIEFEKRQIKKELEhykekgeraeELENELHHLEKENELLQKKITNLKITcekIEALEQENSELERENRKL 675
Cdd:pfam08614 99 RRLAALEAERAQLEEKLK----------DREEELREKRKLNQDLQDELVALQLQ---LNMAEEKLRKLEKENREL 160
|
|
| PRK13922 |
PRK13922 |
rod shape-determining protein MreC; Provisional |
810-851 |
8.59e-03 |
|
rod shape-determining protein MreC; Provisional
Pssm-ID: 237560 Cd Length: 276 Bit Score: 40.35 E-value: 8.59e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 208022632 810 LEQLEKENKSLEQETSQLEKDK---KQLEKENKRLRQQAEIKDTT 851
Cdd:PRK13922 71 LFDLREENEELKKELLELESRLqelEQLEAENARLRELLNLKESL 115
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
768-854 |
8.84e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 40.10 E-value: 8.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 768 LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKissKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Cdd:COG4026 133 LREELLELKEKIDEIAKEKEKLTKENEELESELEELR---EEYKKLREENSILEEEFDNIKSEYSDLKSRFEELLKKRLL 209
|
....*..
gi 208022632 848 KDTTLEE 854
Cdd:COG4026 210 EVFSLEE 216
|
|
| HOOK |
pfam05622 |
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from ... |
776-1241 |
9.00e-03 |
|
HOOK protein coiled-coil region; This family consists of several HOOK1, 2 and 3 proteins from different eukaryotic organizms. The different members of the human gene family are HOOK1, HOOK2 and HOOK3. Different domains have been identified in the three human HOOK proteins, and it was demonstrated that the highly conserved NH2-domain mediates attachment to microtubules, whereas this central coiled-coil motif mediates homodimerization and the more divergent C-terminal domains are involved in binding to specific organelles (organelle-binding domains). It has been demonstrated that endogenous HOOK3 binds to Golgi membranes, whereas both HOOK1 and HOOK2 are localized to discrete but unidentified cellular structures. In mice the Hook1 gene is predominantly expressed in the testis. Hook1 function is necessary for the correct positioning of microtubular structures within the haploid germ cell. Disruption of Hook1 function in mice causes abnormal sperm head shape and fragile attachment of the flagellum to the sperm head. This entry includes the central coiled-coiled domain and the divergent C-terminal domain.
Pssm-ID: 461694 [Multi-domain] Cd Length: 528 Bit Score: 40.83 E-value: 9.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 776 NKKIQQLESELQDLEMENQTLQKNLEELK-------ISSKRLEQLEKENKSLEQETSQLEKDKKQLekenkrlRQQAEIK 848
Cdd:pfam05622 20 DQQVSLLQEEKNSLQQENKKLQERLDQLEsgddsgtPGGKKYLLLQKQLEQLQEENFRLETARDDY-------RIKCEEL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 849 DTTLEENNVKIGNLEK---ENKTLSKEIGIYKESCVRLKELEkenkelvkrATIDiktlvtlredlvSEKLKTQQMNnDL 925
Cdd:pfam05622 93 EKEVLELQHRNEELTSlaeEAQALKDEMDILRESSDKVKKLE---------ATVE------------TYKKKLEDLG-DL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 926 EKLTHELEkiglnkERLLHDEQSTDDRYKllESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEA 1005
Cdd:pfam05622 151 RRQVKLLE------ERNAEYMQRTLQLEE--ELKKANALRGQLETYKRQVQELHGKLSEESKKADKLEFEYKKLEEKLEA 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1006 L---KQRQDEERMVQSsppisgEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQ--ALKTQLKQLETQNNNLQ- 1079
Cdd:pfam05622 223 LqkeKERLIIERDTLR------ETNEELRCAQLQQAELSQADALLSPSSDPGDNLAAEIMpaEIREKLIRLQHENKMLRl 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1080 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKslydslikdh 1159
Cdd:pfam05622 297 GQEGSYRERLTELQQLLEDANRRKNELETQNRLANQRILELQQQVEELQKALQEQGSKAEDSSLLKQKLE---------- 366
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1160 EKLELLHERQAseyesliskhgtlksahknlevehrdledrynQLLKQKGQLEDLE------KMLKVEQEKMLLENKNHE 1233
Cdd:pfam05622 367 EHLEKLHEAQS--------------------------------ELQKKKEQIEELEpkqdsnLAQKIDELQEALRKKDED 414
|
490
....*....|
gi 208022632 1234 TVAAE--YKK 1241
Cdd:pfam05622 415 MKAMEerYKK 424
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
184-340 |
9.29e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 41.20 E-value: 9.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 184 EDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQspcgspgMKRTESRQHLSVELADAKAKIRRL 263
Cdd:TIGR02168 841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL-------ALLRSELEELSEELRELESKRSEL 913
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 208022632 264 RQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLlsdarsarmYRDELDALREKavrVDKLESEVSRYKERLHDIE 340
Cdd:TIGR02168 914 RRELEELREKLAQLELRLEGLEVRIDNLQERLSEE---------YSLTLEEAEAL---ENKIEDDEEEARRRLKRLE 978
|
|
| Atg16_CCD |
cd22887 |
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family ... |
1044-1113 |
9.52e-03 |
|
Coiled-coiled domain of autophagy-related 16 (Atg16) family proteins; The Atg16 family includes Saccharomyces cerevisiae Atg16 (also called cytoplasm to vacuole targeting protein 11, CVT11, or SAP18), human autophagy-related protein 16-1 (also called APG16-like 1, ATG16L1, or APG16L) and autophagy-related protein 16-2 (also called APG16-like 2, ATG16L2, WD repeat-containing protein 80 or WDR80), and similar proteins. Atg16 stabilizes the Atg5-Atg12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. The Atg5-Atg12/Atg16 complex is required for efficient promotion of Atg8-conjugation to phosphatidylethanolamine and Atg8 localization to the pre-autophagosomal structure (PAS). Similarly, human ATG16L1 plays an essential role in autophagy and acts as a molecular scaffold which mediates protein-protein interactions essential for autophagosome formation. ATG16L2, though structurally similar to ATG16L1 and able to form a complex with the autophagy proteins Atg5 and Atg12, is not essential for autophagy. Single-nucleotide polymorphisms in ATG16L1 is associated with an increased risk of developing Crohn disease. Saccharomyces cerevisiae Atg16 contains an N-terminal domain (NTD) that interacts with the Atg5-Atg12 protein conjugate and a coiled-coil domain (CCD) that dimerizes and mediates self-assembly. Human ATG16L1 and ATG16L2 also contains an N-terminal region that binds Atg5, a CCD homologous to the yeast CCD, and a WD40 domain that represents approximately 50% of the full-length protein. This model corresponds to the CCD of Atg16 family proteins.
Pssm-ID: 439196 [Multi-domain] Cd Length: 91 Bit Score: 37.16 E-value: 9.52e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 208022632 1044 KDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1113
Cdd:cd22887 3 ESELQELEKRLAELEAELASLEEEIKDLEEELKEKNKANEILNDELIALQIENNLLEEKLRKLQEENDEL 72
|
|
| |
