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Conserved domains on  [gi|195927006|ref|NP_001124319|]
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apoptosis-inducing factor 1, mitochondrial isoform AIFsh2 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NirB super family cl34210
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
148-319 3.09e-29

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


The actual alignment was detected with superfamily member COG1251:

Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 115.62  E-value: 3.09e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 148 RSIRARDPGARVLIVSEDPELPYMRPPLSKELwfsddpnvtktlrfkqwNGK--ERSIYFQPPSFYvsaqdlphiENGGV 225
Cdd:COG1251   18 EELRKLDPDGEITVIGAEPHPPYNRPPLSKVL-----------------AGEtdEEDLLLRPADFY---------EENGI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 226 AVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAidrAGAEVKSRTTlFRKIGDFRSLEKISREVKSITI 305
Cdd:COG1251   72 DLRLGTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPI---PGADLPGVFT-LRTLDDADALRAALAPGKRVVV 147

                        170
                 ....*....|....
gi 195927006 306 IGGGFLGSELACAL 319
Cdd:COG1251  148 IGGGLIGLEAAAAL 161
AIF-MLS super family cl25936
Mitochondria localization Sequence; This family contains a protein found in eukaryotes. ...
 52-133 1.83e-05

Mitochondria localization Sequence; This family contains a protein found in eukaryotes. Proteins in this family are typically between 240 and 613 amino acids in length. The family is found in association with pfam07992. This protein family is an N-terminal domain for the mitochondrial localization sequence for an apoptosis-inducing factor. The protein is also known as Corneal endothelium-specific protein 1 or as Ovary-specific acidic protein. It is thought to be important for membrane function and is expressed in the ovary and corneal endothelium.


The actual alignment was detected with superfamily member pfam14962:

Pssm-ID: 464407 [Multi-domain]  Cd Length: 192  Bit Score: 44.82  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006   52 RQMASS---GASGgkiDNSVLVLIVGLsTVGAGAY-AYKTMKEDEKRYNERISGLgltpeQKQKKAALSASEGEE---VP 124
Cdd:pfam14962  31 RRMSSNkfpGSSG---SNMIYYLVVGV-TVSAGGYyTYKTVTSEQAKHTEHVTNL-----KEKTKAELHPLQGEKenvAE 101


                  ....*....
gi 195927006  125 QDKAPSHVP 133
Cdd:pfam14962 102 AEKASSEAP 110
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
148-319 3.09e-29

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 115.62  E-value: 3.09e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 148 RSIRARDPGARVLIVSEDPELPYMRPPLSKELwfsddpnvtktlrfkqwNGK--ERSIYFQPPSFYvsaqdlphiENGGV 225
Cdd:COG1251   18 EELRKLDPDGEITVIGAEPHPPYNRPPLSKVL-----------------AGEtdEEDLLLRPADFY---------EENGI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 226 AVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAidrAGAEVKSRTTlFRKIGDFRSLEKISREVKSITI 305
Cdd:COG1251   72 DLRLGTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPI---PGADLPGVFT-LRTLDDADALRAALAPGKRVVV 147

                        170
                 ....*....|....
gi 195927006 306 IGGGFLGSELACAL 319
Cdd:COG1251  148 IGGGLIGLEAAAAL 161
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 150-319 1.81e-17

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 81.21  E-value: 1.81e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006  150 IRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPnvtktlrfkqwngkeRSIYFQPPSFYVSAQDLPHIENGGVAVLT 229
Cdd:pfam07992  17 LTLAQLGGKVTLIEDEGTCPYGGCVLSKALLGAAEA---------------PEIASLWADLYKRKEEVVKKLNNGIEVLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006  230 GKKVVQLD-----VRDNMVKLNDGSQITYEKCLIATGGTPRSLSAidrAGAEvKSRTTLFRKIGDFRSLEKISREvKSIT 304
Cdd:pfam07992  82 GTEVVSIDpgakkVVLEELVDGDGETITYDRLVIATGARPRLPPI---PGVE-LNVGFLVRTLDSAEALRLKLLP-KRVV 156

                         170
                  ....*....|....*
gi 195927006  305 IIGGGFLGSELACAL 319
Cdd:pfam07992 157 VVGGGYIGVELAAAL 171
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 149-322 1.97e-11

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 64.18  E-value: 1.97e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 149 SIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTktlrfkqwngkersiYFQPPSFYVSAQdlphienggVAVL 228
Cdd:PRK09754  21 SLRQQGFTGELHLFSDERHLPYERPPLSKSMLLEDSPQLQ---------------QVLPANWWQENN---------VHLH 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 229 TGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSrttlFRKIGDFRSLEKISREVKSITIIGG 308
Cdd:PRK09754  77 SGVTIKTLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLLDALGERCFT----LRHAGDAARLREVLQPERSVVIVGA 152

                        170
                 ....*....|....*..
gi 195927006 309 GFLGSELA---CALGRK 322
Cdd:PRK09754 153 GTIGLELAasaTQRRCK 169
AIF-MLS pfam14962
Mitochondria localization Sequence; This family contains a protein found in eukaryotes. ...
 52-133 1.83e-05

Mitochondria localization Sequence; This family contains a protein found in eukaryotes. Proteins in this family are typically between 240 and 613 amino acids in length. The family is found in association with pfam07992. This protein family is an N-terminal domain for the mitochondrial localization sequence for an apoptosis-inducing factor. The protein is also known as Corneal endothelium-specific protein 1 or as Ovary-specific acidic protein. It is thought to be important for membrane function and is expressed in the ovary and corneal endothelium.


Pssm-ID: 464407 [Multi-domain]  Cd Length: 192  Bit Score: 44.82  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006   52 RQMASS---GASGgkiDNSVLVLIVGLsTVGAGAY-AYKTMKEDEKRYNERISGLgltpeQKQKKAALSASEGEE---VP 124
Cdd:pfam14962  31 RRMSSNkfpGSSG---SNMIYYLVVGV-TVSAGGYyTYKTVTSEQAKHTEHVTNL-----KEKTKAELHPLQGEKenvAE 101


                  ....*....
gi 195927006  125 QDKAPSHVP 133
Cdd:pfam14962 102 AEKASSEAP 110
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
148-319 3.09e-29

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 115.62  E-value: 3.09e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 148 RSIRARDPGARVLIVSEDPELPYMRPPLSKELwfsddpnvtktlrfkqwNGK--ERSIYFQPPSFYvsaqdlphiENGGV 225
Cdd:COG1251   18 EELRKLDPDGEITVIGAEPHPPYNRPPLSKVL-----------------AGEtdEEDLLLRPADFY---------EENGI 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 226 AVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAidrAGAEVKSRTTlFRKIGDFRSLEKISREVKSITI 305
Cdd:COG1251   72 DLRLGTRVTAIDRAARTVTLADGETLPYDKLVLATGSRPRVPPI---PGADLPGVFT-LRTLDDADALRAALAPGKRVVV 147

                        170
                 ....*....|....
gi 195927006 306 IGGGFLGSELACAL 319
Cdd:COG1251  148 IGGGLIGLEAAAAL 161
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 150-319 1.81e-17

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 81.21  E-value: 1.81e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006  150 IRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPnvtktlrfkqwngkeRSIYFQPPSFYVSAQDLPHIENGGVAVLT 229
Cdd:pfam07992  17 LTLAQLGGKVTLIEDEGTCPYGGCVLSKALLGAAEA---------------PEIASLWADLYKRKEEVVKKLNNGIEVLL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006  230 GKKVVQLD-----VRDNMVKLNDGSQITYEKCLIATGGTPRSLSAidrAGAEvKSRTTLFRKIGDFRSLEKISREvKSIT 304
Cdd:pfam07992  82 GTEVVSIDpgakkVVLEELVDGDGETITYDRLVIATGARPRLPPI---PGVE-LNVGFLVRTLDSAEALRLKLLP-KRVV 156

                         170
                  ....*....|....*
gi 195927006  305 IIGGGFLGSELACAL 319
Cdd:pfam07992 157 VVGGGYIGVELAAAL 171
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 152-322 5.25e-17

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 80.24  E-value: 5.25e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 152 ARDPGARVLIVSEDPELPYMRPPLSKELWFSDDpnvtktlrfkqwngKERSIYFQPPSFYVSAqdlphiengGVAVLTGK 231
Cdd:COG0446    1 RLGPDAEITVIEKGPHHSYQPCGLPYYVGGGIK--------------DPEDLLVRTPESFERK---------GIDVRTGT 57

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 232 KVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLsAIDraGAEVKSRTTLfRKIGDFRSL-EKI-SREVKSITIIGGG 309
Cdd:COG0446   58 EVTAIDPEAKTVTLRDGETLSYDKLVLATGARPRPP-PIP--GLDLPGVFTL-RTLDDADALrEALkEFKGKRAVVIGGG 133

                        170
                 ....*....|....*.
gi 195927006 310 FLGSELACAL---GRK 322
Cdd:COG0446  134 PIGLELAEALrkrGLK 149
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 149-322 1.97e-11

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 64.18  E-value: 1.97e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 149 SIRARDPGARVLIVSEDPELPYMRPPLSKELWFSDDPNVTktlrfkqwngkersiYFQPPSFYVSAQdlphienggVAVL 228
Cdd:PRK09754  21 SLRQQGFTGELHLFSDERHLPYERPPLSKSMLLEDSPQLQ---------------QVLPANWWQENN---------VHLH 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 229 TGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSrttlFRKIGDFRSLEKISREVKSITIIGG 308
Cdd:PRK09754  77 SGVTIKTLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLLDALGERCFT----LRHAGDAARLREVLQPERSVVIVGA 152

                        170
                 ....*....|....*..
gi 195927006 309 GFLGSELA---CALGRK 322
Cdd:PRK09754 153 GTIGLELAasaTQRRCK 169
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 220-321 1.11e-08

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 55.86  E-value: 1.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 220 IENGGVAVLTGKKVVqldVRDNMVKLNDGSQITYEKCLIATGGTPRSLSAIDRAGAEVKSRTTLFrkigdfrSLEKIsre 299
Cdd:COG1249  101 LKKNGVDVIRGRARF---VDPHTVEVTGGETLTADHIVIATGSRPRVPPIPGLDEVRVLTSDEAL-------ELEEL--- 167

                         90       100
                 ....*....|....*....|..
gi 195927006 300 VKSITIIGGGFLGSELACALGR 321
Cdd:COG1249  168 PKSLVVIGGGYIGLEFAQIFAR 189
PRK14989 PRK14989
nitrite reductase subunit NirD; Provisional
 221-319 8.94e-08

nitrite reductase subunit NirD; Provisional


Pssm-ID: 184951 [Multi-domain]  Cd Length: 847  Bit Score: 53.58  E-value: 8.94e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 221 ENGGVAVLTGKKVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPrSLSAIdrAGAEVKSrTTLFRKIGDFRSLEKISREV 300
Cdd:PRK14989  70 EKHGIKVLVGERAITINRQEKVIHSSAGRTVFYDKLIMATGSYP-WIPPI--KGSETQD-CFVYRTIEDLNAIEACARRS 145

                         90
                 ....*....|....*....
gi 195927006 301 KSITIIGGGFLGSELACAL 319
Cdd:PRK14989 146 KRGAVVGGGLLGLEAAGAL 164
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
218-319 2.17e-07

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 51.67  E-value: 2.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 218 PHIENGGVAVLTGKkVVQLDVRDNMVKLNDGSQITYEKCLIATGGTPRsLSAIDraGAE-----VKSR---TTLFRKIgd 289
Cdd:COG1252   64 ELLRRAGVRFIQGE-VTGIDPEARTVTLADGRTLSYDYLVIATGSVTN-FFGIP--GLAehalpLKTLedaLALRERL-- 137

                         90       100       110
                 ....*....|....*....|....*....|.
gi 195927006 290 FRSLEKISREVK-SITIIGGGFLGSELACAL 319
Cdd:COG1252  138 LAAFERAERRRLlTIVVVGGGPTGVELAGEL 168
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 224-319 5.99e-06

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 47.73  E-value: 5.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 224 GVAVLTGKKVVQLDVRDNMVK---LNDGSQI--TYEKCLIATGGTPrSLSAIDraGAEVKSRTTLfRKIGDFRSLEKISR 298
Cdd:PRK09564  70 GIDVKTEHEVVKVDAKNKTITvknLKTGSIFndTYDKLMIATGARP-IIPPIK--NINLENVYTL-KSMEDGLALKELLK 145

                         90       100
                 ....*....|....*....|...
gi 195927006 299 --EVKSITIIGGGFLGSELACAL 319
Cdd:PRK09564 146 deEIKNIVIIGAGFIGLEAVEAA 168
AIF-MLS pfam14962
Mitochondria localization Sequence; This family contains a protein found in eukaryotes. ...
 52-133 1.83e-05

Mitochondria localization Sequence; This family contains a protein found in eukaryotes. Proteins in this family are typically between 240 and 613 amino acids in length. The family is found in association with pfam07992. This protein family is an N-terminal domain for the mitochondrial localization sequence for an apoptosis-inducing factor. The protein is also known as Corneal endothelium-specific protein 1 or as Ovary-specific acidic protein. It is thought to be important for membrane function and is expressed in the ovary and corneal endothelium.


Pssm-ID: 464407 [Multi-domain]  Cd Length: 192  Bit Score: 44.82  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006   52 RQMASS---GASGgkiDNSVLVLIVGLsTVGAGAY-AYKTMKEDEKRYNERISGLgltpeQKQKKAALSASEGEE---VP 124
Cdd:pfam14962  31 RRMSSNkfpGSSG---SNMIYYLVVGV-TVSAGGYyTYKTVTSEQAKHTEHVTNL-----KEKTKAELHPLQGEKenvAE 101


                  ....*....
gi 195927006  125 QDKAPSHVP 133
Cdd:pfam14962 102 AEKASSEAP 110
PRK06116 PRK06116
glutathione reductase; Validated
 221-320 2.01e-04

glutathione reductase; Validated


Pssm-ID: 235701 [Multi-domain]  Cd Length: 450  Bit Score: 42.84  E-value: 2.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 221 ENGGVAVLTGKKVVqldVRDNMVKLNdGSQITYEKCLIATGGTPrslSAIDRAGAE--VKSRttlfrkigDFRSLEKISr 298
Cdd:PRK06116 104 ENNGVDLIEGFARF---VDAHTVEVN-GERYTADHILIATGGRP---SIPDIPGAEygITSD--------GFFALEELP- 167

                         90       100
                 ....*....|....*....|....*
gi 195927006 299 evKSITIIGGGFLGSELAC---ALG 320
Cdd:PRK06116 168 --KRVAVVGAGYIAVEFAGvlnGLG 190
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 219-280 3.13e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 38.84  E-value: 3.13e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 195927006  219 HIENGGVAVLTGKKVVQLDVRDNM--VKLNDGSQITYEKCLIATGGTPRSLSAiDRAGAEVKSR 280
Cdd:pfam07992 202 ALEKNGVEVRLGTSVKEIIGDGDGveVILKDGTEIDADLVVVAIGRRPNTELL-EAAGLELDER 264
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 224-316 3.60e-03

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 38.97  E-value: 3.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 224 GVAVLTGKKVVQldvrdnmVKLNDGSQ-ITYEKCLIATGGTPRSLSAIDRAGaevksrttlfRKIGDFR---SLEKISre 299
Cdd:PRK06416 112 GEAKLVDPNTVR-------VMTEDGEQtYTAKNIILATGSRPRELPGIEIDG----------RVIWTSDealNLDEVP-- 172

                         90
                 ....*....|....*..
gi 195927006 300 vKSITIIGGGFLGSELA 316
Cdd:PRK06416 173 -KSLVVIGGGYIGVEFA 188
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
243-322 3.93e-03

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 38.60  E-value: 3.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 243 VKLNDGS--QITYEKCLIATGGTPRSLSAIDRAGaevksrttlfRKIGDFRSLEKISREVKSITIIGGGFLGSELAC--- 317
Cdd:PRK05249 126 VECPDGEveTLTADKIVIATGSRPYRPPDVDFDH----------PRIYDSDSILSLDHLPRSLIIYGAGVIGCEYASifa 195


                 ....*
gi 195927006 318 ALGRK 322
Cdd:PRK05249 196 ALGVK 200
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 224-321 4.87e-03

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 38.62  E-value: 4.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 195927006 224 GVAVLTGKKVVQLDvrdnmvklndGSQITYEKCLIATGGTPRSLSAIDRA-GAEVKSRTTLFrkigdfrSLEKISrevKS 302
Cdd:PRK06292 112 GTARFVDPNTVEVN----------GERIEAKNIVIATGSRVPPIPGVWLIlGDRLLTSDDAF-------ELDKLP---KS 171

                         90
                 ....*....|....*....
gi 195927006 303 ITIIGGGFLGSELACALGR 321
Cdd:PRK06292 172 LAVIGGGVIGLELGQALSR 190
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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