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Conserved domains on  [gi|188497635|ref|NP_001120842|]
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cell division cycle-associated 7-like protein isoform 2 [Homo sapiens]

Protein Classification

cell division cycle-associated 7 family protein( domain architecture ID 10564696)

cell division cycle-associated 7 (CDCA7) family protein similar to human CDCA7 that may play a role as transcriptional regulator, and participates in MYC-mediated cell transformation and apoptosis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-4CXXC_R1 pfam10497
Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor ...
 311-409 1.13e-64

Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor that inhibits monoamine oxidase A gene expression. This domain is a four-CXXC zinc finger putative DNA-binding domain found at the C-terminal end of R1. The domain carries 12 cysteines of which four pairs are of the CXXC type.


:

Pssm-ID: 463117  Cd Length: 99  Bit Score: 202.11  E-value: 1.13e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188497635  311 YDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCAT 390
Cdd:pfam10497   1 YDSVNGKTCHQCRQKTLDTKTSCRNSQCKGVRGQFCGDCLRNRYGENVEEALANPDWICPKCRGICNCSFCRKKKGLAPT 80

                          90
                  ....*....|....*....
gi 188497635  391 GILIHLAKFYGYDNVKEYL 409
Cdd:pfam10497  81 GILYHKAKALGFSSVAHYL 99
 
Name Accession Description Interval E-value
zf-4CXXC_R1 pfam10497
Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor ...
 311-409 1.13e-64

Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor that inhibits monoamine oxidase A gene expression. This domain is a four-CXXC zinc finger putative DNA-binding domain found at the C-terminal end of R1. The domain carries 12 cysteines of which four pairs are of the CXXC type.


Pssm-ID: 463117  Cd Length: 99  Bit Score: 202.11  E-value: 1.13e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188497635  311 YDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCAT 390
Cdd:pfam10497   1 YDSVNGKTCHQCRQKTLDTKTSCRNSQCKGVRGQFCGDCLRNRYGENVEEALANPDWICPKCRGICNCSFCRKKKGLAPT 80

                          90
                  ....*....|....*....
gi 188497635  391 GILIHLAKFYGYDNVKEYL 409
Cdd:pfam10497  81 GILYHKAKALGFSSVAHYL 99
 
Name Accession Description Interval E-value
zf-4CXXC_R1 pfam10497
Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor ...
 311-409 1.13e-64

Zinc-finger domain of monoamine-oxidase A repressor R1; R1 is a transcription factor repressor that inhibits monoamine oxidase A gene expression. This domain is a four-CXXC zinc finger putative DNA-binding domain found at the C-terminal end of R1. The domain carries 12 cysteines of which four pairs are of the CXXC type.


Pssm-ID: 463117  Cd Length: 99  Bit Score: 202.11  E-value: 1.13e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188497635  311 YDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCAT 390
Cdd:pfam10497   1 YDSVNGKTCHQCRQKTLDTKTSCRNSQCKGVRGQFCGDCLRNRYGENVEEALANPDWICPKCRGICNCSFCRKKKGLAPT 80

                          90
                  ....*....|....*....
gi 188497635  391 GILIHLAKFYGYDNVKEYL 409
Cdd:pfam10497  81 GILYHKAKALGFSSVAHYL 99
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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