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Conserved domains on  [gi|188035886|ref|NP_001120826|]
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Krtap2-4-like [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Keratin_B2 super family cl37504
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 8-131 3.65e-10

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


The actual alignment was detected with superfamily member pfam01500:

Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 54.41  E-value: 3.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188035886    8 SFSSQSCGGGCCQPCCCRDPCCCRPVSCQTTVCRPVTCVPHCTRPICEP-----CRRPICCDPCSLQQGC---------- 72
Cdd:pfam01500  13 TCSTGGTCGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPccqtsCCQPTCCQTSSCQTGCggigygqegs 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188035886   73 ----------CRPITCCPTSCTAVVCRPCCWASTCCQPISVQAPCCRPPCCQPAPCRTTCRTSPCNTCC 131
Cdd:pfam01500  93 sgavssrtrwCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAQASCCRPSYCGQSCCRPACCCQCSEPTC 161
 
Name Accession Description Interval E-value
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 8-131 3.65e-10

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 54.41  E-value: 3.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188035886    8 SFSSQSCGGGCCQPCCCRDPCCCRPVSCQTTVCRPVTCVPHCTRPICEP-----CRRPICCDPCSLQQGC---------- 72
Cdd:pfam01500  13 TCSTGGTCGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPccqtsCCQPTCCQTSSCQTGCggigygqegs 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188035886   73 ----------CRPITCCPTSCTAVVCRPCCWASTCCQPISVQAPCCRPPCCQPAPCRTTCRTSPCNTCC 131
Cdd:pfam01500  93 sgavssrtrwCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAQASCCRPSYCGQSCCRPACCCQCSEPTC 161
 
Name Accession Description Interval E-value
Keratin_B2 pfam01500
Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized ...
 8-131 3.65e-10

Keratin, high sulfur B2 protein; High sulfur proteins are cysteine-rich proteins synthesized during the differentiation of hair matrix cells, and form hair fibres in association with hair keratin intermediate filaments. This family has been divided up into four regions, with the second region containing 8 copies of a short repeat. This family is also known as B2 or KAP1.


Pssm-ID: 366678 [Multi-domain]  Cd Length: 161  Bit Score: 54.41  E-value: 3.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 188035886    8 SFSSQSCGGGCCQPCCCRDPCCCRPVSCQTTVCRPVTCVPHCTRPICEP-----CRRPICCDPCSLQQGC---------- 72
Cdd:pfam01500  13 TCSTGGTCGSGCCQPCCCQSSCCRPSCCQTSCCQPTTFQSSCCRPTCQPccqtsCCQPTCCQTSSCQTGCggigygqegs 92

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 188035886   73 ----------CRPITCCPTSCTAVVCRPCCWASTCCQPISVQAPCCRPPCCQPAPCRTTCRTSPCNTCC 131
Cdd:pfam01500  93 sgavssrtrwCRPDCRVEGTCLPPCCVVSCTPPTCCQLHHAQASCCRPSYCGQSCCRPACCCQCSEPTC 161
Keratin_B2_2 pfam13885
Keratin, high sulfur B2 protein;
57-101 6.46e-05

Keratin, high sulfur B2 protein;


Pssm-ID: 464017 [Multi-domain]  Cd Length: 45  Bit Score: 38.13  E-value: 6.46e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 188035886   57 CRRPICCDPCSLQQGCCRPITCCPTSCTAVVCRPCCWASTCCQPI 101
Cdd:pfam13885   1 CCQPSCCQPSCCQPSCCQPSCCQPSCCQPSCCRPSCCRSSCCQPT 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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