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Conserved domains on  [gi|171543879|ref|NP_001116370|]
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CD99 antigen isoform b precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CD99L2 super family cl13702
CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this ...
 34-163 2.11e-05

CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this family are typically between 165 and 237 amino acids in length. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum.


The actual alignment was detected with superfamily member pfam12301:

Pssm-ID: 463526  Cd Length: 162  Bit Score: 42.50  E-value: 2.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171543879   34 GDDFDLGDAVvDGENDdprppnppkPMPNPNPNHPSSSGSFSDADLADGVSGGE-----GKGGSDGGGSHRKEGEEADAP 108
Cdd:pfam12301  38 PDDFDLSDAL-DPEND---------IPGKGPNKGGSGGGGFSDDDLEDVAEGGGykpdkGKGGGRGGSNDDGGSDQPAET 107

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 171543879  109 GVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKenaEQGEVDMESHRNANAEPAVQ 163
Cdd:pfam12301 108 GTIAGIVSAVAMALLGAVSSYISYQKKKLCFS---IQQGLNAEYVKGENLEAVVA 159
 
Name Accession Description Interval E-value
CD99L2 pfam12301
CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this ...
 34-163 2.11e-05

CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this family are typically between 165 and 237 amino acids in length. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum.


Pssm-ID: 463526  Cd Length: 162  Bit Score: 42.50  E-value: 2.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171543879   34 GDDFDLGDAVvDGENDdprppnppkPMPNPNPNHPSSSGSFSDADLADGVSGGE-----GKGGSDGGGSHRKEGEEADAP 108
Cdd:pfam12301  38 PDDFDLSDAL-DPEND---------IPGKGPNKGGSGGGGFSDDDLEDVAEGGGykpdkGKGGGRGGSNDDGGSDQPAET 107

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 171543879  109 GVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKenaEQGEVDMESHRNANAEPAVQ 163
Cdd:pfam12301 108 GTIAGIVSAVAMALLGAVSSYISYQKKKLCFS---IQQGLNAEYVKGENLEAVVA 159
 
Name Accession Description Interval E-value
CD99L2 pfam12301
CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this ...
 34-163 2.11e-05

CD99 antigen like protein 2; This family of proteins is found in eukaryotes. Proteins in this family are typically between 165 and 237 amino acids in length. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum.


Pssm-ID: 463526  Cd Length: 162  Bit Score: 42.50  E-value: 2.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 171543879   34 GDDFDLGDAVvDGENDdprppnppkPMPNPNPNHPSSSGSFSDADLADGVSGGE-----GKGGSDGGGSHRKEGEEADAP 108
Cdd:pfam12301  38 PDDFDLSDAL-DPEND---------IPGKGPNKGGSGGGGFSDDDLEDVAEGGGykpdkGKGGGRGGSNDDGGSDQPAET 107

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 171543879  109 GVIPGIVGAVVVAVAGAISSFIAYQKKKLCFKenaEQGEVDMESHRNANAEPAVQ 163
Cdd:pfam12301 108 GTIAGIVSAVAMALLGAVSSYISYQKKKLCFS---IQQGLNAEYVKGENLEAVVA 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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