NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|164698498|ref|NP_001106965|]
View 

septin-9 isoform b [Homo sapiens]

Protein Classification

septin family protein( domain architecture ID 13243274)

septin family protein, a filament-forming cytoskeletal GTPase, is involved in various cellular processes, including cytoskeleton organization, cytokinesis, and membrane dynamics

CATH:  3.40.50.300
Gene Ontology:  GO:0005525|GO:0003924|GO:0061640|GO:0060090
PubMed:  14611653|12445407|12111093|17637674|18478031

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CDC_Septin cd01850
CDC/Septin GTPase family; Septins are a conserved family of GTP-binding proteins associated ...
 288-562 2.03e-174

CDC/Septin GTPase family; Septins are a conserved family of GTP-binding proteins associated with diverse processes in dividing and non-dividing cells. They were first discovered in the budding yeast S. cerevisiae as a set of genes (CDC3, CDC10, CDC11 and CDC12) required for normal bud morphology. Septins are also present in metazoan cells, where they are required for cytokinesis in some systems, and implicated in a variety of other processes involving organization of the cell cortex and exocytosis. In humans, 12 septin genes generate dozens of polypeptides, many of which comprise heterooligomeric complexes. Since septin mutants are commonly defective in cytokinesis and formation of the neck formation of the neck filaments/septin rings, septins have been considered to be the primary constituents of the neck filaments. Septins belong to the GTPase superfamily for their conserved GTPase motifs and enzymatic activities.


:

Pssm-ID: 206649  Cd Length: 275  Bit Score: 494.37  E-value: 2.03e-174
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 288 QGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNEN 367
Cdd:cd01850    1 RGFQFNIMVVGESGLGKSTFINTLFGTKLYPSKYPPAPGEHITKTVEIKISKAELEENGVKLKLTVIDTPGFGDNINNSD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 368 CWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEER 447
Cdd:cd01850   81 CWKPIVDYIDDQFESYLREESRINRNRRIPDTRVHCCLYFIPPTGHGLKPLDIEFMKKLSKKVNIIPVIAKADTLTPEEL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 448 VHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFA 527
Cdd:cd01850  161 TEFKKRIMEDIEENNIKIYKFPEDEEDEEEIEENKKLKSLIPFAIVGSNEEVEVNGKKVRGRKYPWGVVEVENEEHCDFV 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 164698498 528 YLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGS 562
Cdd:cd01850  241 KLRNLLIRTHLQDLKETTHNVHYENYRSEKLEALK 275
PHA03269 super family cl29788
envelope glycoprotein C; Provisional
 143-271 5.78e-08

envelope glycoprotein C; Provisional


The actual alignment was detected with superfamily member PHA03269:

Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 55.50  E-value: 5.78e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 143 TEITIVKPQESAHRRMEPPA-SKVPEVPTAPATDAAPKRVEIQMPKPAEAPTapspAQTLENSEPAPVSQLQSRLEPKPQ 221
Cdd:PHA03269  24 TNIPIPELHTSAATQKPDPApAPHQAASRAPDPAVAPTSAASRKPDLAQAPT----PAASEKFDPAPAPHQAASRAPDPA 99

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 164698498 222 --PPVAEA-TPRSQEATEAAPSCVGDMADTPRDAGLKQA-PASRNEKAPVDFGY 271
Cdd:PHA03269 100 vaPQLAAApKPDAAEAFTSAAQAHEAPADAGTSAASKKPdPAAHTQHSPPPFAY 153
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 32-240 8.19e-06

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 8.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498   32 PNSTPPR-RVQTPLLRATVASSTQKFQDLgvkNSEPSArhvdslsqrsPKASLRRVELSGPKAAEPVSRR--TELSIDIS 108
Cdd:PHA03247 2767 PAPAPPAaPAAGPPRRLTRPAVASLSESR---ESLPSP----------WDPADPPAAVLAPAAALPPAASpaGPLPPPTS 2833

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  109 SKQVENAGAIGPSRFGLKRAevlGHKTPE-PAPRR--TEITIVKPQESAHrrmePPASKVPEVPTAPATDAAPKRVEIQM 185
Cdd:PHA03247 2834 AQPTAPPPPPGPPPPSLPLG---GSVAPGgDVRRRppSRSPAAKPAAPAR----PPVRRLARPAVSRSTESFALPPDQPE 2906

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 164698498  186 PKPaeAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAeatPRSQEATEAAPS 240
Cdd:PHA03247 2907 RPP--QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA---PTTDPAGAGEPS 2956
 
Name Accession Description Interval E-value
CDC_Septin cd01850
CDC/Septin GTPase family; Septins are a conserved family of GTP-binding proteins associated ...
 288-562 2.03e-174

CDC/Septin GTPase family; Septins are a conserved family of GTP-binding proteins associated with diverse processes in dividing and non-dividing cells. They were first discovered in the budding yeast S. cerevisiae as a set of genes (CDC3, CDC10, CDC11 and CDC12) required for normal bud morphology. Septins are also present in metazoan cells, where they are required for cytokinesis in some systems, and implicated in a variety of other processes involving organization of the cell cortex and exocytosis. In humans, 12 septin genes generate dozens of polypeptides, many of which comprise heterooligomeric complexes. Since septin mutants are commonly defective in cytokinesis and formation of the neck formation of the neck filaments/septin rings, septins have been considered to be the primary constituents of the neck filaments. Septins belong to the GTPase superfamily for their conserved GTPase motifs and enzymatic activities.


Pssm-ID: 206649  Cd Length: 275  Bit Score: 494.37  E-value: 2.03e-174
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 288 QGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNEN 367
Cdd:cd01850    1 RGFQFNIMVVGESGLGKSTFINTLFGTKLYPSKYPPAPGEHITKTVEIKISKAELEENGVKLKLTVIDTPGFGDNINNSD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 368 CWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEER 447
Cdd:cd01850   81 CWKPIVDYIDDQFESYLREESRINRNRRIPDTRVHCCLYFIPPTGHGLKPLDIEFMKKLSKKVNIIPVIAKADTLTPEEL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 448 VHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFA 527
Cdd:cd01850  161 TEFKKRIMEDIEENNIKIYKFPEDEEDEEEIEENKKLKSLIPFAIVGSNEEVEVNGKKVRGRKYPWGVVEVENEEHCDFV 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 164698498 528 YLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGS 562
Cdd:cd01850  241 KLRNLLIRTHLQDLKETTHNVHYENYRSEKLEALK 275
Septin pfam00735
Septin; Members of this family include CDC3, CDC10, CDC11 and CDC12/Septin. Members of this ...
 289-558 1.90e-138

Septin; Members of this family include CDC3, CDC10, CDC11 and CDC12/Septin. Members of this family bind GTP. As regards the septins, these are polypeptides of 30-65kDa with three characteriztic GTPase motifs (G-1, G-3 and G-4) that are similar to those of the Ras family. The G-4 motif is strictly conserved with a unique septin consensus of AKAD. Most septins are thought to have at least one coiled-coil region, which in some cases is necessary for intermolecular interactions that allow septins to polymerize to form rod-shaped complexes. In turn, these are arranged into tandem arrays to form filaments. They are multifunctional proteins, with roles in cytokinesis, sporulation, germ cell development, exocytosis and apoptosis.


Pssm-ID: 395596  Cd Length: 272  Bit Score: 402.83  E-value: 1.90e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  289 GFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENC 368
Cdd:pfam00735   1 GFDFTLMVVGESGLGKTTFINTLFLTDLYRARGIPGPSEKIKKTVEIKAYTVEIEEDGVKLNLTVIDTPGFGDAIDNSNC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  369 WQPIMKFINDQYEKYLQEEVNINRKKRIpDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERV 448
Cdd:pfam00735  81 WRPIVEYIDEQYEQYLRDESGLNRKSIK-DNRVHCCLYFISPTGHGLKPLDVEFMKKLSEKVNIIPVIAKADTLTPDELQ 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  449 HFKQRITADLLSNGIDVYPQKEFDEDS-EDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFA 527
Cdd:pfam00735 160 RFKKRIREEIERQNIPIYHFPDEESDEdEEKELNEQLKSSIPFAIVGSNTVIENDGEKVRGRKYPWGVVEVENPSHCDFL 239

                         250       260       270
                  ....*....|....*....|....*....|.
gi 164698498  528 YLRDLLIRTHMQNIKDITSSIHFEAYRVKRL 558
Cdd:pfam00735 240 KLRNMLIRTHLQDLKEVTHELHYETYRSEKL 270
CDC3 COG5019
Septin family protein [Cell cycle control, cell division, chromosome partitioning, ...
 270-576 8.34e-129

Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 227352 [Multi-domain]  Cd Length: 373  Bit Score: 382.06  E-value: 8.34e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 270 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISR-KSVQPTSEERIPKTIEIKSITHDIEEKGVR 348
Cdd:COG5019    2 GYVGISNLPNQRHRKLSKKGIDFTIMVVGESGLGKTTFINTLFGTSLVDeTEIDDIRAEGTSPTLEIKITKAELEEDGFH 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 349 MKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSK 428
Cdd:COG5019   82 LNLTVIDTPGFGDFIDNSKCWEPIVDYIDDQFDQYLDEEQKIKRNPKFKDTRVHACLYFIRPTGHGLKPLDIEAMKRLSK 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 429 VVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRL-VNEKFREMIPFAVVGSDHEYQVNGKRIL 507
Cdd:COG5019  162 RVNLIPVIAKADTLTDDELAEFKERIREDLEQYNIPVFDPYDPEDDEDESLeENQDLRSLIPFAIIGSNTEIENGGEQVR 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 164698498 508 GRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLnEGSSAMANGMEEKEPEA 576
Cdd:COG5019  242 GRKYPWGVVEIDDEEHSDFKKLRNLLIRTHLQELKETTENLLYENYRTEKL-SGLKNSGEPSLKEIHEA 309
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 143-271 5.78e-08

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 55.50  E-value: 5.78e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 143 TEITIVKPQESAHRRMEPPA-SKVPEVPTAPATDAAPKRVEIQMPKPAEAPTapspAQTLENSEPAPVSQLQSRLEPKPQ 221
Cdd:PHA03269  24 TNIPIPELHTSAATQKPDPApAPHQAASRAPDPAVAPTSAASRKPDLAQAPT----PAASEKFDPAPAPHQAASRAPDPA 99

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 164698498 222 --PPVAEA-TPRSQEATEAAPSCVGDMADTPRDAGLKQA-PASRNEKAPVDFGY 271
Cdd:PHA03269 100 vaPQLAAApKPDAAEAFTSAAQAHEAPADAGTSAASKKPdPAAHTQHSPPPFAY 153
small_GTP TIGR00231
small GTP-binding protein domain; Proteins with a small GTP-binding domain recognized by this ...
 291-358 1.49e-06

small GTP-binding protein domain; Proteins with a small GTP-binding domain recognized by this model include Ras, RhoA, Rab11, translation elongation factor G, translation initiation factor IF-2, tetratcycline resistance protein TetM, CDC42, Era, ADP-ribosylation factors, tdhF, and many others. In some proteins the domain occurs more than once.This model recognizes a large number of small GTP-binding proteins and related domains in larger proteins. Note that the alpha chains of heterotrimeric G proteins are larger proteins in which the NKXD motif is separated from the GxxxxGK[ST] motif (P-loop) by a long insert and are not easily detected by this model. [Unknown function, General]


Pssm-ID: 272973 [Multi-domain]  Cd Length: 162  Bit Score: 48.52  E-value: 1.49e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 164698498  291 EFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIpktieiksITHDIEEKGVRMKLTVIDTPG 358
Cdd:TIGR00231   1 DIKIVIVGHPNVGKSTLLNSLLGNKGSITEYYPGTTRNY--------VTTVIEEDGKTYKFNLLDTAG 60
PHA03247 PHA03247
large tegument protein UL36; Provisional
 32-240 8.19e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 8.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498   32 PNSTPPR-RVQTPLLRATVASSTQKFQDLgvkNSEPSArhvdslsqrsPKASLRRVELSGPKAAEPVSRR--TELSIDIS 108
Cdd:PHA03247 2767 PAPAPPAaPAAGPPRRLTRPAVASLSESR---ESLPSP----------WDPADPPAAVLAPAAALPPAASpaGPLPPPTS 2833

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  109 SKQVENAGAIGPSRFGLKRAevlGHKTPE-PAPRR--TEITIVKPQESAHrrmePPASKVPEVPTAPATDAAPKRVEIQM 185
Cdd:PHA03247 2834 AQPTAPPPPPGPPPPSLPLG---GSVAPGgDVRRRppSRSPAAKPAAPAR----PPVRRLARPAVSRSTESFALPPDQPE 2906

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 164698498  186 PKPaeAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAeatPRSQEATEAAPS 240
Cdd:PHA03247 2907 RPP--QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA---PTTDPAGAGEPS 2956
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 22-223 5.79e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 43.06  E-value: 5.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498    22 RSFEVEEVETPNSTPPRRVQTpllratvasstqkfqdlgvKNSEPSARHVDSLSQRSPKASLRRVELSGPKAA--EPVSR 99
Cdd:TIGR00927  259 PTFLTREVETDLLTSPRSVVE-------------------KNTLTTPRRVESNSSTNHWGLVGKNNLTTPQGTvlEHTPA 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498   100 RTELSIDISSKQvenagaigPSRFGLKRAEVLGHKTPEPAPRrTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAP- 178
Cdd:TIGR00927  320 TSEGQVTISIMT--------GSSPAETKASTAAWKIRNPLSR-TSAPAVRIASATFRGLEKNPSTAPSTPATPRVRAVLt 390

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 164698498   179 ---KRVEIQMPKPAeAPTAPSPAQT--LENSEPAP-VSQL---QSRLEPKPQPP 223
Cdd:TIGR00927  391 tqvHHCVVVKPAPA-VPTTPSPSLTtaLFPEAPSPsPSALppgQPDLHPKAEYP 443
PLN03118 PLN03118
Rab family protein; Provisional
 292-358 7.90e-04

Rab family protein; Provisional


Pssm-ID: 215587 [Multi-domain]  Cd Length: 211  Bit Score: 41.19  E-value: 7.90e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 164698498 292 FNIMVVGQSGLGKSTLINTLFKSKIsrKSVQPTseerIPKTIEIKSITHDieekGVRMKLTVIDTPG 358
Cdd:PLN03118  15 FKILLIGDSGVGKSSLLVSFISSSV--EDLAPT----IGVDFKIKQLTVG----GKRLKLTIWDTAG 71
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 149-231 1.76e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.15  E-value: 1.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 149 KPQESAHRRM--EPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPA--QTLEN------SEPAPVSQLQSrleP 218
Cdd:NF033838 397 KAEEEAKRKAaeEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAEQPKAEKPAdqQAEEDyarrseEEYNRLTQQQP---P 473

                         90
                 ....*....|...
gi 164698498 219 KPQPPVAEATPRS 231
Cdd:NF033838 474 KTEKPAQPSTPKT 486
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 136-267 4.01e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 39.75  E-value: 4.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 136 PEPAPRRTEITIVKPQESAHRRmepPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSR 215
Cdd:NF040712 205 LAREPADARPEEVEPAPAAEGA---PATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPP 281

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 164698498 216 LEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKAPV 267
Cdd:NF040712 282 APGAAETPEAAEPPAPAPAAPAAPAAPEAEEPARPEPPPAPKPKRRRRRASV 333
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
141-208 4.41e-03

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 39.98  E-value: 4.41e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 164698498 141 RRTEITIVKPQESAHRRMEP-PASKVPEVPTAPATDAAPkrVEIQMPKPAEAPTAPSPAQTLENSEPAP 208
Cdd:COG5373   31 EELEAELAEAAEAASAPAEPePEAAAAATAAAPEAAPAP--VPEAPAAPPAAAEAPAPAAAAPPAEAEP 97
DUF3729 pfam12526
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ...
 150-236 5.94e-03

Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.


Pssm-ID: 372164 [Multi-domain]  Cd Length: 115  Bit Score: 36.98  E-value: 5.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  150 PQESAHRRMEPPaskvPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPvsqLQSRLEPKpqPPVAEATP 229
Cdd:pfam12526  31 PPESAHPDPPPP----VGDPRPPVVDTPPPVSAVWVLPPPSEPAAPEPDLVPPVTGPAG---PPSPLAPP--APAQKPPL 101


                  ....*..
gi 164698498  230 RSQEATE 236
Cdd:pfam12526 102 PPPRPQR 108
 
Name Accession Description Interval E-value
CDC_Septin cd01850
CDC/Septin GTPase family; Septins are a conserved family of GTP-binding proteins associated ...
 288-562 2.03e-174

CDC/Septin GTPase family; Septins are a conserved family of GTP-binding proteins associated with diverse processes in dividing and non-dividing cells. They were first discovered in the budding yeast S. cerevisiae as a set of genes (CDC3, CDC10, CDC11 and CDC12) required for normal bud morphology. Septins are also present in metazoan cells, where they are required for cytokinesis in some systems, and implicated in a variety of other processes involving organization of the cell cortex and exocytosis. In humans, 12 septin genes generate dozens of polypeptides, many of which comprise heterooligomeric complexes. Since septin mutants are commonly defective in cytokinesis and formation of the neck formation of the neck filaments/septin rings, septins have been considered to be the primary constituents of the neck filaments. Septins belong to the GTPase superfamily for their conserved GTPase motifs and enzymatic activities.


Pssm-ID: 206649  Cd Length: 275  Bit Score: 494.37  E-value: 2.03e-174
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 288 QGFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNEN 367
Cdd:cd01850    1 RGFQFNIMVVGESGLGKSTFINTLFGTKLYPSKYPPAPGEHITKTVEIKISKAELEENGVKLKLTVIDTPGFGDNINNSD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 368 CWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEER 447
Cdd:cd01850   81 CWKPIVDYIDDQFESYLREESRINRNRRIPDTRVHCCLYFIPPTGHGLKPLDIEFMKKLSKKVNIIPVIAKADTLTPEEL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 448 VHFKQRITADLLSNGIDVYPQKEFDEDSEDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFA 527
Cdd:cd01850  161 TEFKKRIMEDIEENNIKIYKFPEDEEDEEEIEENKKLKSLIPFAIVGSNEEVEVNGKKVRGRKYPWGVVEVENEEHCDFV 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 164698498 528 YLRDLLIRTHMQNIKDITSSIHFEAYRVKRLNEGS 562
Cdd:cd01850  241 KLRNLLIRTHLQDLKETTHNVHYENYRSEKLEALK 275
Septin pfam00735
Septin; Members of this family include CDC3, CDC10, CDC11 and CDC12/Septin. Members of this ...
 289-558 1.90e-138

Septin; Members of this family include CDC3, CDC10, CDC11 and CDC12/Septin. Members of this family bind GTP. As regards the septins, these are polypeptides of 30-65kDa with three characteriztic GTPase motifs (G-1, G-3 and G-4) that are similar to those of the Ras family. The G-4 motif is strictly conserved with a unique septin consensus of AKAD. Most septins are thought to have at least one coiled-coil region, which in some cases is necessary for intermolecular interactions that allow septins to polymerize to form rod-shaped complexes. In turn, these are arranged into tandem arrays to form filaments. They are multifunctional proteins, with roles in cytokinesis, sporulation, germ cell development, exocytosis and apoptosis.


Pssm-ID: 395596  Cd Length: 272  Bit Score: 402.83  E-value: 1.90e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  289 GFEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLTVIDTPGFGDHINNENC 368
Cdd:pfam00735   1 GFDFTLMVVGESGLGKTTFINTLFLTDLYRARGIPGPSEKIKKTVEIKAYTVEIEEDGVKLNLTVIDTPGFGDAIDNSNC 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  369 WQPIMKFINDQYEKYLQEEVNINRKKRIpDTRVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPVIAKADTLTLEERV 448
Cdd:pfam00735  81 WRPIVEYIDEQYEQYLRDESGLNRKSIK-DNRVHCCLYFISPTGHGLKPLDVEFMKKLSEKVNIIPVIAKADTLTPDELQ 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  449 HFKQRITADLLSNGIDVYPQKEFDEDS-EDRLVNEKFREMIPFAVVGSDHEYQVNGKRILGRKTKWGTIEVENTTHCEFA 527
Cdd:pfam00735 160 RFKKRIREEIERQNIPIYHFPDEESDEdEEKELNEQLKSSIPFAIVGSNTVIENDGEKVRGRKYPWGVVEVENPSHCDFL 239

                         250       260       270
                  ....*....|....*....|....*....|.
gi 164698498  528 YLRDLLIRTHMQNIKDITSSIHFEAYRVKRL 558
Cdd:pfam00735 240 KLRNMLIRTHLQDLKEVTHELHYETYRSEKL 270
CDC3 COG5019
Septin family protein [Cell cycle control, cell division, chromosome partitioning, ...
 270-576 8.34e-129

Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 227352 [Multi-domain]  Cd Length: 373  Bit Score: 382.06  E-value: 8.34e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 270 GYVGIDSILEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISR-KSVQPTSEERIPKTIEIKSITHDIEEKGVR 348
Cdd:COG5019    2 GYVGISNLPNQRHRKLSKKGIDFTIMVVGESGLGKTTFINTLFGTSLVDeTEIDDIRAEGTSPTLEIKITKAELEEDGFH 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 349 MKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCCLYFIPATGHSLRPLDIEFMKRLSK 428
Cdd:COG5019   82 LNLTVIDTPGFGDFIDNSKCWEPIVDYIDDQFDQYLDEEQKIKRNPKFKDTRVHACLYFIRPTGHGLKPLDIEAMKRLSK 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 429 VVNIVPVIAKADTLTLEERVHFKQRITADLLSNGIDVYPQKEFDEDSEDRL-VNEKFREMIPFAVVGSDHEYQVNGKRIL 507
Cdd:COG5019  162 RVNLIPVIAKADTLTDDELAEFKERIREDLEQYNIPVFDPYDPEDDEDESLeENQDLRSLIPFAIIGSNTEIENGGEQVR 241

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 164698498 508 GRKTKWGTIEVENTTHCEFAYLRDLLIRTHMQNIKDITSSIHFEAYRVKRLnEGSSAMANGMEEKEPEA 576
Cdd:COG5019  242 GRKYPWGVVEIDDEEHSDFKKLRNLLIRTHLQELKETTENLLYENYRTEKL-SGLKNSGEPSLKEIHEA 309
YeeP COG3596
Predicted GTPase [General function prediction only];
242-361 3.86e-09

Predicted GTPase [General function prediction only];


Pssm-ID: 442815 [Multi-domain]  Cd Length: 318  Bit Score: 58.24  E-value: 3.86e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 242 VGDMADTPRDAGLKQAPASRNEKapvdfgyvgIDSILEQMRRKAMkqgfEFNIMVVGQSGLGKSTLINTLFKSKISRKSV 321
Cdd:COG3596    3 TEVSSLTERLEALKRLPQVLREL---------LAEALERLLVELP----PPVIALVGKTGAGKSSLINALFGAEVAEVGV 69

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 164698498 322 qptseeRIPKTIEIKSITHDIEEKGVrmkLTVIDTPGFGD 361
Cdd:COG3596   70 ------GRPCTREIQRYRLESDGLPG---LVLLDTPGLGE 100
Ras_like_GTPase cd00882
Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like ...
 296-467 5.43e-09

Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Ras-like GTPase superfamily. The Ras-like superfamily of small GTPases consists of several families with an extremely high degree of structural and functional similarity. The Ras superfamily is divided into at least four families in eukaryotes: the Ras, Rho, Rab, and Sar1/Arf families. This superfamily also includes proteins like the GTP translation factors, Era-like GTPases, and G-alpha chain of the heterotrimeric G proteins. Members of the Ras superfamily regulate a wide variety of cellular functions: the Ras family regulates gene expression, the Rho family regulates cytoskeletal reorganization and gene expression, the Rab and Sar1/Arf families regulate vesicle trafficking, and the Ran family regulates nucleocytoplasmic transport and microtubule organization. The GTP translation factor family regulates initiation, elongation, termination, and release in translation, and the Era-like GTPase family regulates cell division, sporulation, and DNA replication. Members of the Ras superfamily are identified by the GTP binding site, which is made up of five characteristic sequence motifs, and the switch I and switch II regions.


Pssm-ID: 206648 [Multi-domain]  Cd Length: 161  Bit Score: 55.54  E-value: 5.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 296 VVGQSGLGKSTLINTLFKSKISrksvqPTSEERIPkTIEIKSITHDIEEKGVrmKLTVIDTPGFGDhinnencwqpimkf 375
Cdd:cd00882    2 VVGRGGVGKSSLLNALLGGEVG-----EVSDVPGT-TRDPDVYVKELDKGKV--KLVLVDTPGLDE-------------- 59

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 376 indqyEKYLQEEvninRKKRIPDTRVHCCLYFIPATGH-SLRPLDIEFMKRLSKV-VNIVPVIAKADTLTLEERVHFKQR 453
Cdd:cd00882   60 -----FGGLGRE----ELARLLLRGADLILLVVDSTDReSEEDAKLLILRRLRKEgIPIILVGNKIDLLEEREVEELLRL 130

                        170
                 ....*....|....
gi 164698498 454 ITAdLLSNGIDVYP 467
Cdd:cd00882  131 EEL-AKILGVPVFE 143
Toc34_like cd01853
Translocon at the Outer-envelope membrane of Chloroplasts 34-like (Toc34-like); The Toc34-like ...
 253-407 4.68e-08

Translocon at the Outer-envelope membrane of Chloroplasts 34-like (Toc34-like); The Toc34-like (Translocon at the Outer-envelope membrane of Chloroplasts) family contains several Toc proteins, including Toc34, Toc33, Toc120, Toc159, Toc86, Toc125, and Toc90. The Toc complex at the outer envelope membrane of chloroplasts is a molecular machine of ~500 kDa that contains a single Toc159 protein, four Toc75 molecules, and four or five copies of Toc34. Toc64 and Toc12 are associated with the translocon, but do not appear to be part of the core complex. The Toc translocon initiates the import of nuclear-encoded preproteins from the cytosol into the organelle. Toc34 and Toc159 are both GTPases, while Toc75 is a beta-barrel integral membrane protein. Toc159 is equally distributed between a soluble cytoplasmic form and a membrane-inserted form, suggesting that assembly of the Toc complex is dynamic. Toc34 and Toc75 act sequentially to mediate docking and insertion of Toc159 resulting in assembly of the functional translocon.


Pssm-ID: 206652  Cd Length: 248  Bit Score: 54.25  E-value: 4.68e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 253 GLKQAPASRNEKApvdfgyvgidsiLEQMRRKAMKQGFEFNIMVVGQSGLGKSTLINTLF---KSKISRKSVQPTSEERI 329
Cdd:cd01853    5 GFQFFPDATQTKL------------HELEAKLKKELDFSLTILVLGKTGVGKSSTINSIFgerKVSVSAFQSETLRPREV 72

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 164698498 330 PKTIeiksithdieeKGVrmKLTVIDTPGFgdhinNENCWQPIMKFINDQYEKYLqeevninrKKRIPDtrvhCCLYF 407
Cdd:cd01853   73 SRTV-----------DGF--KLNIIDTPGL-----LESQDQRVNRKILSIIKRFL--------KKKTID----VVLYV 120
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 143-271 5.78e-08

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 55.50  E-value: 5.78e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 143 TEITIVKPQESAHRRMEPPA-SKVPEVPTAPATDAAPKRVEIQMPKPAEAPTapspAQTLENSEPAPVSQLQSRLEPKPQ 221
Cdd:PHA03269  24 TNIPIPELHTSAATQKPDPApAPHQAASRAPDPAVAPTSAASRKPDLAQAPT----PAASEKFDPAPAPHQAASRAPDPA 99

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 164698498 222 --PPVAEA-TPRSQEATEAAPSCVGDMADTPRDAGLKQA-PASRNEKAPVDFGY 271
Cdd:PHA03269 100 vaPQLAAApKPDAAEAFTSAAQAHEAPADAGTSAASKKPdPAAHTQHSPPPFAY 153
PHA03247 PHA03247
large tegument protein UL36; Provisional
 134-260 7.80e-07

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 52.63  E-value: 7.80e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  134 KTPEPAPRRTEITIVKPQESAHRRMEPPASKV----PEVPTAPATDAAPKRVeiqmPKPAEAPTAPSPAqtlenSEPAPV 209
Cdd:PHA03247 2706 PTPEPAPHALVSATPLPPGPAAARQASPALPAapapPAVPAGPATPGGPARP----ARPPTTAGPPAPA-----PPAAPA 2776

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 164698498  210 SQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGlKQAPAS 260
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP-AASPAG 2826
DLP_2 cd09912
Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; The ...
 292-467 9.09e-07

Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; The dynamin family of large mechanochemical GTPases includes the classical dynamins and dynamin-like proteins (DLPs) that are found throughout the Eukarya. This family also includes bacterial DLPs. These proteins catalyze membrane fission during clathrin-mediated endocytosis. Dynamin consists of five domains; an N-terminal G domain that binds and hydrolyzes GTP, a middle domain (MD) involved in self-assembly and oligomerization, a pleckstrin homology (PH) domain responsible for interactions with the plasma membrane, GED, which is also involved in self-assembly, and a proline arginine rich domain (PRD) that interacts with SH3 domains on accessory proteins. To date, three vertebrate dynamin genes have been identified; dynamin 1, which is brain specific, mediates uptake of synaptic vesicles in presynaptic terminals; dynamin-2 is expressed ubiquitously and similarly participates in membrane fission; mutations in the MD, PH and GED domains of dynamin 2 have been linked to human diseases such as Charcot-Marie-Tooth peripheral neuropathy and rare forms of centronuclear myopathy. Dynamin 3 participates in megakaryocyte progenitor amplification, and is also involved in cytoplasmic enlargement and the formation of the demarcation membrane system. This family also includes mitofusins (MFN1 and MFN2 in mammals) that are involved in mitochondrial fusion. Dynamin oligomerizes into helical structures around the neck of budding vesicles in a GTP hydrolysis-dependent manner.


Pssm-ID: 206739 [Multi-domain]  Cd Length: 180  Bit Score: 49.47  E-value: 9.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 292 FNIMVVGQSGLGKSTLINTLFkskisRKSVQPTSEerIPKTIEIKSITHDIeEKGVrmklTVIDTPGFGDHINNencwqp 371
Cdd:cd09912    1 FLLAVVGEFSAGKSTLLNALL-----GEEVLPTGV--TPTTAVITVLRYGL-LKGV----VLVDTPGLNSTIEH------ 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 372 imkfindqyekyLQEEVninrKKRIPdtRVHCCLYFIPAtGHSLRPLDIEFMKRLSKVV--NIVPVIAKADTLT---LEE 446
Cdd:cd09912   63 ------------HTEIT----ESFLP--RADAVIFVLSA-DQPLTESEREFLKEILKWSgkKIFFVLNKIDLLSeeeLEE 123

                        170       180
                 ....*....|....*....|...
gi 164698498 447 RVHFKQRITA--DLLSNGIDVYP 467
Cdd:cd09912  124 VLEYSREELGvlELGGGEPRIFP 146
MMR_HSR1 pfam01926
50S ribosome-binding GTPase; The full-length GTPase protein is required for the complete ...
 293-436 9.39e-07

50S ribosome-binding GTPase; The full-length GTPase protein is required for the complete activity of the protein of interacting with the 50S ribosome and binding of both adenine and guanine nucleotides, with a preference for guanine nucleotide.


Pssm-ID: 460387 [Multi-domain]  Cd Length: 113  Bit Score: 47.61  E-value: 9.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  293 NIMVVGQSGLGKSTLINTLF--KSKISRKSvqptseeriPKTIEIksITHDIEEKGVRMKLtvIDTPGFgdhinnencwq 370
Cdd:pfam01926   1 RVALVGRPNVGKSTLINALTgaKAIVSDYP---------GTTRDP--NEGRLELKGKQIIL--VDTPGL----------- 56

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 164698498  371 pimkfindqYEKYLQEEVNINRKKRIpdTRVHCCLYFIPATgHSLRPLDIEFMKRLSKvvNIVPVI 436
Cdd:pfam01926  57 ---------IEGASEGEGLGRAFLAI--IEADLILFVVDSE-EGITPLDEELLELLRE--NKKPII 108
small_GTP TIGR00231
small GTP-binding protein domain; Proteins with a small GTP-binding domain recognized by this ...
 291-358 1.49e-06

small GTP-binding protein domain; Proteins with a small GTP-binding domain recognized by this model include Ras, RhoA, Rab11, translation elongation factor G, translation initiation factor IF-2, tetratcycline resistance protein TetM, CDC42, Era, ADP-ribosylation factors, tdhF, and many others. In some proteins the domain occurs more than once.This model recognizes a large number of small GTP-binding proteins and related domains in larger proteins. Note that the alpha chains of heterotrimeric G proteins are larger proteins in which the NKXD motif is separated from the GxxxxGK[ST] motif (P-loop) by a long insert and are not easily detected by this model. [Unknown function, General]


Pssm-ID: 272973 [Multi-domain]  Cd Length: 162  Bit Score: 48.52  E-value: 1.49e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 164698498  291 EFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSEERIpktieiksITHDIEEKGVRMKLTVIDTPG 358
Cdd:TIGR00231   1 DIKIVIVGHPNVGKSTLLNSLLGNKGSITEYYPGTTRNY--------VTTVIEEDGKTYKFNLLDTAG 60
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 134-244 4.00e-06

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 49.71  E-value: 4.00e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 134 KTPEPAPRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRV-----EIQMPKPAEAPTAPSPAQTLENSEPAP 208
Cdd:PRK14951 379 KTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVaapaaAAPAAAPAAAPAAVALAPAPPAQAAPE 458

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 164698498 209 VSQLQSRLEPKPQPPVAEATPRSQEA-TEAAPSCVGD 244
Cdd:PRK14951 459 TVAIPVRVAPEPAVASAAPAPAAAPAaARLTPTEEGD 495
PHA03247 PHA03247
large tegument protein UL36; Provisional
 32-240 8.19e-06

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 49.17  E-value: 8.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498   32 PNSTPPR-RVQTPLLRATVASSTQKFQDLgvkNSEPSArhvdslsqrsPKASLRRVELSGPKAAEPVSRR--TELSIDIS 108
Cdd:PHA03247 2767 PAPAPPAaPAAGPPRRLTRPAVASLSESR---ESLPSP----------WDPADPPAAVLAPAAALPPAASpaGPLPPPTS 2833

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  109 SKQVENAGAIGPSRFGLKRAevlGHKTPE-PAPRR--TEITIVKPQESAHrrmePPASKVPEVPTAPATDAAPKRVEIQM 185
Cdd:PHA03247 2834 AQPTAPPPPPGPPPPSLPLG---GSVAPGgDVRRRppSRSPAAKPAAPAR----PPVRRLARPAVSRSTESFALPPDQPE 2906

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 164698498  186 PKPaeAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAeatPRSQEATEAAPS 240
Cdd:PHA03247 2907 RPP--QPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLA---PTTDPAGAGEPS 2956
GTPase_YqeH TIGR03597
ribosome biogenesis GTPase YqeH; This family describes YqeH, a member of a larger family of ...
 273-373 1.02e-05

ribosome biogenesis GTPase YqeH; This family describes YqeH, a member of a larger family of GTPases involved in ribosome biogenesis. Like YqlF, it shows a cyclical permutation relative to GTPases EngA (in which the GTPase domain is duplicated), Era, and others. Members of this protein family are found in a relatively small number of bacterial species, including Bacillus subtilis but not Escherichia coli. [Protein synthesis, Other]


Pssm-ID: 213834 [Multi-domain]  Cd Length: 360  Bit Score: 48.00  E-value: 1.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  273 GIDSILEQMRRKAMKQgfefNIMVVGQSGLGKSTLINTLFKSKISRKSVQPTSeeRIPKTieiksiTHDIEEKGVRMKLT 352
Cdd:TIGR03597 140 GIDELLDKIKKARNKK----DVYVVGVTNVGKSSLINKLLKQNNGDKDVITTS--PFPGT------TLDLIEIPLDDGHS 207

                          90       100
                  ....*....|....*....|....*.
gi 164698498  353 VIDTPGFGD-----HINNENCWQPIM 373
Cdd:TIGR03597 208 LYDTPGIINshqmaHYLDKKDLKYIT 233
YqeH cd01855
Circularly permuted YqeH GTPase; YqeH is an essential GTP-binding protein. Depletion of YqeH ...
 273-359 1.30e-05

Circularly permuted YqeH GTPase; YqeH is an essential GTP-binding protein. Depletion of YqeH induces an excess initiation of DNA replication, suggesting that it negatively controls initiation of chromosome replication. The YqeH subfamily is common in eukaryotes and sporadically present in bacteria with probable acquisition by plants from chloroplasts. Proteins of the YqeH family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases.


Pssm-ID: 206748 [Multi-domain]  Cd Length: 191  Bit Score: 46.10  E-value: 1.30e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 273 GIDSILEQMRRKAMKQGfefNIMVVGQSGLGKSTLINTLFKSKisRKSVQPTSEERIPKTIEIKSITHDIEEKGVRMKLT 352
Cdd:cd01855  110 GVEELIEEIKKLAKYRG---DVYVVGATNVGKSTLINALLKSN--GGKVQAQALVQRLTVSPIPGTTLGLIKIPLGEGKK 184


                 ....*..
gi 164698498 353 VIDTPGF 359
Cdd:cd01855  185 LYDTPGI 191
Gem1 COG1100
GTPase SAR1 family domain [General function prediction only];
290-463 1.42e-05

GTPase SAR1 family domain [General function prediction only];


Pssm-ID: 440717 [Multi-domain]  Cd Length: 177  Bit Score: 45.74  E-value: 1.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 290 FEFNIMVVGQSGLGKSTLINTLFKSKISRKSVQPtseeripkTIEIKSITHDIEEKGVRMKLTVIDTPGfgdhinnencw 369
Cdd:COG1100    2 GEKKIVVVGTGGVGKTSLVNRLVGDIFSLEKYLS--------TNGVTIDKKELKLDGLDVDLVIWDTPG----------- 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 370 QPIMKFINDQYEKYLQEevninrkkripdtrVHCCLYFI----PATGHSLrPLDIEFMKRLSKVVNIVPVIAKADtLTLE 445
Cdd:COG1100   63 QDEFRETRQFYARQLTG--------------ASLYLFVVdgtrEETLQSL-YELLESLRRLGKKSPIILVLNKID-LYDE 126

                        170
                 ....*....|....*...
gi 164698498 446 ERVHFKQRITADLLSNGI 463
Cdd:COG1100  127 EEIEDEERLKEALSEDNI 144
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 150-266 4.67e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 46.21  E-value: 4.67e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 150 PQESAHRRMEPPASKVPEVpTAPATDAAPKRVEIQMPKPAEAPtapSPAQTLENSEPAPVsqlQSRLEPKPQPPVAEATP 229
Cdd:PRK14959 389 PASGGAATIPTPGTQGPQG-TAPAAGMTPSSAAPATPAPSAAP---SPRVPWDDAPPAPP---RSGIPPRPAPRMPEASP 461

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 164698498 230 rsqeaTEAAPSCVGDMADTPRDAGLKQAPASRNEKAP 266
Cdd:PRK14959 462 -----VPGAPDSVASASDAPPTLGDPSDTAEHTPSGP 493
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
135-268 5.00e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 46.41  E-value: 5.00e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 135 TPEPAPRRTEITivKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLEnSEPAPVSQLQS 214
Cdd:PRK12323 405 APAAAPAAAAAA--RAVAAAPARRSPAPEALAAARQASARGPGGAPAPAPAPAAAPAAAARPAAAGPR-PVAAAAAAAPA 481

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 164698498 215 RLEPKPQP-PVAEATPRSQEATEAAPSCVGDMADtPRDAGLKQAPASRNEKAPVD 268
Cdd:PRK12323 482 RAAPAAAPaPADDDPPPWEELPPEFASPAPAQPD-AAPAGWVAESIPDPATADPD 535
AIG1 pfam04548
AIG1 family; Arabidopsis protein AIG1 appears to be involved in plant resistance to bacteria.
 293-358 5.44e-05

AIG1 family; Arabidopsis protein AIG1 appears to be involved in plant resistance to bacteria.


Pssm-ID: 398307 [Multi-domain]  Cd Length: 200  Bit Score: 44.52  E-value: 5.44e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 164698498  293 NIMVVGQSGLGKSTLINTL-----FKSKISRKSVQPTSEE--RIPKTIEIKsithdieekgvrmkltVIDTPG 358
Cdd:pfam04548   2 RIVLVGKTGNGKSATGNSIlgrkaFESKLRAQGVTKTCQLvsRTWDGRIIN----------------VIDTPG 58
YfjP cd11383
YfjP GTPase; The Era (E. coli Ras-like protein)-like YfjP subfamily includes several ...
 297-360 5.74e-05

YfjP GTPase; The Era (E. coli Ras-like protein)-like YfjP subfamily includes several uncharacterized bacterial GTPases that are similar to Era. They generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain.


Pssm-ID: 206743 [Multi-domain]  Cd Length: 140  Bit Score: 43.10  E-value: 5.74e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 164698498 297 VGQSGLGKSTLINTLFKSKISRKSVqptseeRIPKTIEIKSITHDIEEKGvrmkLTVIDTPGFG 360
Cdd:cd11383    3 MGKTGAGKSSLCNALFGTEVAAVGD------RRPTTRAAQAYVWQTGGDG----LVLLDLPGVG 56
PLN03209 PLN03209
translocon at the inner envelope of chloroplast subunit 62; Provisional
 96-262 5.97e-05

translocon at the inner envelope of chloroplast subunit 62; Provisional


Pssm-ID: 178748 [Multi-domain]  Cd Length: 576  Bit Score: 46.07  E-value: 5.97e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  96 PVSRRTELSIDISSKQV---ENAGAIGPSRFGLKRAEVLGHKTP-EPAPRRTEITIVKPQE--SAHRRMEPPASKVPEVP 169
Cdd:PLN03209 312 PLTPMEELLAKIPSQRVppkESDAADGPKPVPTKPVTPEAPSPPiEEEPPQPKAVVPRPLSpyTAYEDLKPPTSPIPTPP 391

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 170 TAPAtdAAPKRVE-IQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSR----------LEPKPQP-PVAEATPRSQEATEA 237
Cdd:PLN03209 392 SSSP--ASSKSVDaVAKPAEPDVVPSPGSASNVPEVEPAQVEAKKTRplspyaryedLKPPTSPsPTAPTGVSPSVSSTS 469

                        170       180
                 ....*....|....*....|....*
gi 164698498 238 APSCVGDMAdTPRDAGLKQAPASRN 262
Cdd:PLN03209 470 SVPAVPDTA-PATAATDAAAPPPAN 493
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 136-252 6.24e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 46.13  E-value: 6.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 136 PEPAPRRteitiVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSR 215
Cdd:PRK07764 406 PAAAPAP-----AAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAP 480

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 164698498 216 LEPKPQPPVAEATPRSQEATEAAPScvGDMADTPRDA 252
Cdd:PRK07764 481 APAPPAAPAPAAAPAAPAAPAAPAG--ADDAATLRER 515
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
111-266 6.93e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 46.00  E-value: 6.93e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 111 QVENAGAIGPSRFGLKRAEVLGHKTPEPAPRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAE 190
Cdd:PRK07003 373 PARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPVPAK 452

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 164698498 191 APTAPSPAQTLENSEPAPVSQLQSRLEP---KPQPPVAEATPRSQEATEAAPSCVGDmADTPRDAGLKQAPASRNEKAP 266
Cdd:PRK07003 453 ANARASADSRCDERDAQPPADSGSASAPasdAPPDAAFEPAPRAAAPSAATPAAVPD-ARAPAAASREDAPAAAAPPAP 530
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
132-277 9.45e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 45.25  E-value: 9.45e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 132 GHKTPEPAPRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMP-KPAEAPTAPSPAQTLENSEPAPVS 210
Cdd:PRK12323 369 GGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPaRRSPAPEALAAARQASARGPGGAP 448

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 164698498 211 QLQSRLEPKPQP--PVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPAsrnEKAPVDFGYVGIDSI 277
Cdd:PRK12323 449 APAPAPAAAPAAaaRPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPW---EELPPEFASPAPAQP 514
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 139-267 9.94e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.55  E-value: 9.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  139 APRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVeiQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEP 218
Cdd:PHA03307   61 ACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPARE--GSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEML 138

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 164698498  219 KPQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKAPV 267
Cdd:PHA03307  139 RPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPS 187
YjeQ_EngC cd01854
Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; ...
 273-359 1.09e-04

Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; YjeQ (YloQ in Bacillus subtilis) is a ribosomal small subunit-dependent GTPase; hence also known as RsgA. YjeQ is a late-stage ribosomal biogenesis factor involved in the 30S subunit maturation, and it represents a protein family whose members are broadly conserved in bacteria and have been shown to be essential to the growth of E. coli and B. subtilis. Proteins of the YjeQ family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. All YjeQ family proteins display a unique domain architecture, which includes an N-terminal OB-fold RNA-binding domain, the central permuted GTPase domain, and a zinc knuckle-like C-terminal cysteine domain.


Pssm-ID: 206747 [Multi-domain]  Cd Length: 211  Bit Score: 43.54  E-value: 1.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 273 GIDSILEQMRRKamkqgfefNIMVVGQSGLGKSTLINTLFKskisrKSVQPTSEERipktieiKSI-------TH----D 341
Cdd:cd01854   75 GLDELRELLKGK--------TSVLVGQSGVGKSTLLNALLP-----ELVLATGEIS-------EKLgrgrhttTHrelfP 134

                         90
                 ....*....|....*...
gi 164698498 342 IEEKGVrmkltVIDTPGF 359
Cdd:cd01854  135 LPGGGL-----IIDTPGF 147
3a0901s04IAP86 TIGR00993
chloroplast protein import component Toc86/159, G and M domains; The long precursor of the 86K ...
 290-376 1.41e-04

chloroplast protein import component Toc86/159, G and M domains; The long precursor of the 86K protein originally described is proposed to have three domains. The N-terminal A-domain is acidic, repetitive, weakly conserved, readily removed by proteolysis during chloroplast isolation, and not required for protein translocation. The other domains are designated G (GTPase) and M (membrane anchor); this family includes most of the G domain and all of M. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273381 [Multi-domain]  Cd Length: 763  Bit Score: 44.94  E-value: 1.41e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  290 FEFNIMVVGQSGLGKSTLINTLF-KSKISRKSVQPTSeeripktieiKSIThDIEEKGVRMKLTVIDTPGF----GDHIN 364
Cdd:TIGR00993 117 FSLNILVLGKSGVGKSATINSIFgEVKFSTDAFGMGT----------TSVQ-EIEGLVQGVKIRVIDTPGLkssaSDQSK 185

                          90
                  ....*....|..
gi 164698498  365 NENCWQPIMKFI 376
Cdd:TIGR00993 186 NEKILSSVKKFI 197
Era_like cd00880
E. coli Ras-like protein (Era)-like GTPase; The Era (E. coli Ras-like protein)-like family ...
 296-361 1.65e-04

E. coli Ras-like protein (Era)-like GTPase; The Era (E. coli Ras-like protein)-like family includes several distinct subfamilies (TrmE/ThdF, FeoB, YihA (EngB), Era, and EngA/YfgK) that generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. TrmE is ubiquitous in bacteria and is a widespread mitochondrial protein in eukaryotes, but is absent from archaea. The yeast member of TrmE family, MSS1, is involved in mitochondrial translation; bacterial members are often present in translation-related operons. FeoB represents an unusual adaptation of GTPases for high-affinity iron (II) transport. YihA (EngB) family of GTPases is typified by the E. coli YihA, which is an essential protein involved in cell division control. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain. EngA and its orthologs are composed of two GTPase domains and, since the sequences of the two domains are more similar to each other than to other GTPases, it is likely that an ancient gene duplication, rather than a fusion of evolutionarily distinct GTPases, gave rise to this family.


Pssm-ID: 206646 [Multi-domain]  Cd Length: 161  Bit Score: 42.23  E-value: 1.65e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 164698498 296 VVGQSGLGKSTLINTLFKSKISRKSVQP-TSEERIPKTIEIKSIThdieekgvrmKLTVIDTPGFGD 361
Cdd:cd00880    2 IFGRPNVGKSSLLNALLGQNVGIVSPIPgTTRDPVRKEWELLPLG----------PVVLIDTPGLDE 58
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
33-246 1.65e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 44.48  E-value: 1.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  33 NSTPPRRVQTPLLRATVASStqkfqdlgvknSEPSARHVDSLSQRSPKASLRRVELSGPKAAEPVSRRTELSIDISSKQV 112
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAA-----------APAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQA 439

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 113 ENAGAIGPSRFGLKRAEVlghktPEPAPRRTeitIVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVEI--QMPKPAE 190
Cdd:PRK12323 440 SARGPGGAPAPAPAPAAA-----PAAAARPA---AAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELppEFASPAP 511

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 164698498 191 APTAPSPAQTLENSEPAPVSQLQS--RLEPKPQPPVAEATPRSQEATEAAPSCVGDMA 246
Cdd:PRK12323 512 AQPDAAPAGWVAESIPDPATADPDdaFETLAPAPAAAPAPRAAAATEPVVAPRPPRAS 569
PHA03247 PHA03247
large tegument protein UL36; Provisional
 135-261 1.77e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 44.93  E-value: 1.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  135 TPEPAPRRTEITIvkpQESAHRRMEPPASKVPEVP---------TAPATDAAPKRVEIQMPKPAEAP---------TAPS 196
Cdd:PHA03247 2570 PPRPAPRPSEPAV---TSRARRPDAPPQSARPRAPvddrgdprgPAPPSPLPPDTHAPDPPPPSPSPaanepdphpPPTV 2646

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 164698498  197 PAQTLENSEPAPVS-QLQSRLEPKPQPPVAEATPRSQEaTEAAPSCVGDMADTPRDAGLKQAPASR 261
Cdd:PHA03247 2647 PPPERPRDDPAPGRvSRPRRARRLGRAAQASSPPQRPR-RRAARPTVGSLTSLADPPPPPPTPEPA 2711
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 160-245 1.87e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 44.42  E-value: 1.87e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 160 PPASKVPEVPTAPATDAA-PKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAA 238
Cdd:PRK14950 362 PVPAPQPAKPTAAAPSPVrPTPAPSTRPKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPESAPKLTRAAIPVDEK 441


                 ....*..
gi 164698498 239 PSCVGDM 245
Cdd:PRK14950 442 PKYTPPA 448
PHA03378 PHA03378
EBNA-3B; Provisional
 136-265 1.94e-04

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 44.67  E-value: 1.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 136 PEPAPR-RTEITIVKPQESAHRRMEPPAS---KVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTlenSEPAPVSQ 211
Cdd:PHA03378 711 PGRAQRpAAATGRARPPAAAPGRARPPAAapgRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPP---PQAPPAPQ 787

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 164698498 212 LQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRD---AGLKQA-PASRNEKA 265
Cdd:PHA03378 788 QRPRGAPTPQPPPQAGPTSMQLMPRAAPGQQGPTKQILRQlltGGVKRGrPSLKKPAA 845
YlqF cd01856
Circularly permuted YlqF GTPase; Proteins of the YlqF family contain all sequence motifs ...
 274-358 1.96e-04

Circularly permuted YlqF GTPase; Proteins of the YlqF family contain all sequence motifs typical of the vast class of P-loop-containing GTPases, but show a circular permutation, with a G4-G1-G3 pattern of motifs as opposed to the regular G1-G3-G4 pattern seen in most GTPases. The YlqF subfamily is represented in all eukaryotes as well as a phylogenetically diverse array of bacteria (including gram-positive bacteria, proteobacteria, Synechocystis, Borrelia, and Thermotoga).


Pssm-ID: 206749 [Multi-domain]  Cd Length: 171  Bit Score: 42.13  E-value: 1.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 274 IDSILEQMRRKAMKQGF--EFNIMVVGQSGLGKSTLINTLFKSKISRKSVQP--TseeripKTIEIKSITHDIEekgvrm 349
Cdd:cd01856   96 AKKLLKENEKLKAKGLLprPLRAMVVGIPNVGKSTLINRLRGKKVAKVGNKPgvT------RGQQWIRIGPNIE------ 163


                 ....*....
gi 164698498 350 kltVIDTPG 358
Cdd:cd01856  164 ---LLDTPG 169
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 134-225 2.13e-04

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 44.33  E-value: 2.13e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 134 KTPEPAPRRTEITIVKPQ------ESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTapSPAQTLENSEPA 207
Cdd:PHA03269  52 RAPDPAVAPTSAASRKPDlaqaptPAASEKFDPAPAPHQAASRAPDPAVAPQLAAAPKPDAAEAFT--SAAQAHEAPADA 129

                         90       100
                 ....*....|....*....|...
gi 164698498 208 PVSQLQSRLEP-----KPQPPVA 225
Cdd:PHA03269 130 GTSAASKKPDPaahtqHSPPPFA 152
kgd PRK12270
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ...
 158-244 2.24e-04

multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;


Pssm-ID: 237030 [Multi-domain]  Cd Length: 1228  Bit Score: 44.50  E-value: 2.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  158 MEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSqlqsrlePKPQPPVAEATPRSQEATEA 237
Cdd:PRK12270   36 YGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAA-------AAAAAAAPAAPPAAAAAAAP 108


                  ....*..
gi 164698498  238 APSCVGD 244
Cdd:PRK12270  109 AAAAVED 115
YihA_EngB cd01876
YihA (EngB) GTPase family; The YihA (EngB) subfamily of GTPases is typified by the E. coli ...
 294-447 2.67e-04

YihA (EngB) GTPase family; The YihA (EngB) subfamily of GTPases is typified by the E. coli YihA, an essential protein involved in cell division control. YihA and its orthologs are small proteins that typically contain less than 200 amino acid residues and consists of the GTPase domain only (some of the eukaryotic homologs contain an N-terminal extension of about 120 residues that might be involved in organellar targeting). Homologs of yihA are found in most Gram-positive and Gram-negative pathogenic bacteria, with the exception of Mycobacterium tuberculosis. The broad-spectrum nature of YihA and its essentiality for cell viability in bacteria make it an attractive antibacterial target.


Pssm-ID: 206665 [Multi-domain]  Cd Length: 170  Bit Score: 41.73  E-value: 2.67e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 294 IMVVGQSGLGKSTLINTLFKskisRKSVQPTSeeRIP-KTIEIksITHDIEEkgvrmKLTVIDTPGFG----DHINNENc 368
Cdd:cd01876    2 VAFAGRSNVGKSSLINALTN----RKKLARTS--KTPgRTQLI--NFFNVGD-----KFRLVDLPGYGyakvSKEVREK- 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 369 WQPIMkfindqyEKYLQEEVNINRkkripdtrvhccLYFIPATGHSLRPLDIEFMKRLSKV-VNIVPVIAKADTLTLEER 447
Cdd:cd01876   68 WGKLI-------EEYLENRENLKG------------VVLLIDARHGPTPIDLEMLEFLEELgIPFLIVLTKADKLKKSEL 128
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
89-266 3.23e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.71  E-value: 3.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  89 SGPKAAEPVSRRTELSIDISSKQVENAGAIGPSRFGLKRAEVLGHKTPEPAPrrtEITIVKPQESAHRrmepPASKVPEV 168
Cdd:PRK12323 379 AAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAP---EALAAARQASARG----PGGAPAPA 451

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 169 PTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPqPPVAEATPRSQEATEAApscvGDMADT 248
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELP-PEFASPAPAQPDAAPAG----WVAESI 526

                        170
                 ....*....|....*...
gi 164698498 249 PRDaGLKQAPASRNEKAP 266
Cdd:PRK12323 527 PDP-ATADPDDAFETLAP 543
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 149-267 3.41e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 43.55  E-value: 3.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 149 KPQeSAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTA--PSPAQTLENSEPAPVSQLQSRLEPKPQPPVAE 226
Cdd:PRK14951 365 KPA-AAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAaaSAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPA 443

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 164698498 227 ATPRSQEATEAAPSCVGDMADT--PRDAGLKQAPASRNEKAPV 267
Cdd:PRK14951 444 AVALAPAPPAQAAPETVAIPVRvaPEPAVASAAPAPAAAPAAA 486
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
63-261 3.58e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 43.33  E-value: 3.58e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  63 NSEPSARHVDSLSQRSPKASLRRVELSGPKAAEPVSRRTELSIDISSKQVENAGAIGPSRFGLKRAEVLGHKTPEPAPRR 142
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPAP 450

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 143 TEITIVKPQESAHRRM---EPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPsPAQTLENSEPAPVsqlQSRLEPK 219
Cdd:PRK12323 451 APAPAAAPAAAARPAAagpRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEF-ASPAPAQPDAAPA---GWVAESI 526

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 164698498 220 PQPPVAEATPRSQEATEAAPSCVgdmADTPRDAGLKQAPASR 261
Cdd:PRK12323 527 PDPATADPDDAFETLAPAPAAAP---APRAAAATEPVVAPRP 565
PHA03247 PHA03247
large tegument protein UL36; Provisional
 34-229 4.01e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 4.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498   34 STPPRRVQTPLLRATVASSTQkFQDLGVKNSEPSAR-HVDSLSQRSPKASLRRVELSGPKAAEPVSRRTElsidisskqv 112
Cdd:PHA03247 2677 SSPPQRPRRRAARPTVGSLTS-LADPPPPPPTPEPApHALVSATPLPPGPAAARQASPALPAAPAPPAVP---------- 2745

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  113 enAGAIGPSRFGLKRAEVLGHKTPEPAPRRTeitivkPQESAHRRMEPP--ASKVPEVPTAPA-TDAAPKRVEIQMPKPA 189
Cdd:PHA03247 2746 --AGPATPGGPARPARPPTTAGPPAPAPPAA------PAAGPPRRLTRPavASLSESRESLPSpWDPADPPAAVLAPAAA 2817

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 164698498  190 EaPTAPSPAQTLensePAPVSQLQSRlEPKPQPPVAEATP 229
Cdd:PHA03247 2818 L-PPAASPAGPL----PPPTSAQPTA-PPPPPGPPPPSLP 2851
PHA03247 PHA03247
large tegument protein UL36; Provisional
 135-240 4.07e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.77  E-value: 4.07e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  135 TPEPAPRRTEITIVKPQESAhRRMEPPASKVPEVPTAPATDAAPKrvEIQMPKPAEAPTAPS----PAQTLENSEPAPVS 210
Cdd:PHA03247 2736 PAAPAPPAVPAGPATPGGPA-RPARPPTTAGPPAPAPPAAPAAGP--PRRLTRPAVASLSESreslPSPWDPADPPAAVL 2812

                          90       100       110
                  ....*....|....*....|....*....|
gi 164698498  211 QLQSRLEPKPQPPVAEATPRSqeATEAAPS 240
Cdd:PHA03247 2813 APAAALPPAASPAGPLPPPTS--AQPTAPP 2840
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 150-252 4.68e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 43.05  E-value: 4.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 150 PQESAHRRMEPPASKVPEvPTAPATDAAPKRVEIQMPKPAEAP-TAPSPAQTLENSEPAPVSQLQSRLEPKPQP-PVAEA 227
Cdd:PRK07764 394 PAAAAPSAAAAAPAAAPA-PAAAAPAAAAAPAPAAAPQPAPAPaPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPaPAPAA 472

                         90       100
                 ....*....|....*....|....*
gi 164698498 228 TPRSQEATEAAPSCVGDMADTPRDA 252
Cdd:PRK07764 473 APEPTAAPAPAPPAAPAPAAAPAAP 497
Era cd04163
E. coli Ras-like protein (Era) is a multifunctional GTPase; Era (E. coli Ras-like protein) is ...
 286-467 5.10e-04

E. coli Ras-like protein (Era) is a multifunctional GTPase; Era (E. coli Ras-like protein) is a multifunctional GTPase found in all bacteria except some eubacteria. It binds to the 16S ribosomal RNA (rRNA) of the 30S subunit and appears to play a role in the assembly of the 30S subunit, possibly by chaperoning the 16S rRNA. It also contacts several assembly elements of the 30S subunit. Era couples cell growth with cytokinesis and plays a role in cell division and energy metabolism. Homologs have also been found in eukaryotes. Era contains two domains: the N-terminal GTPase domain and a C-terminal domain KH domain that is critical for RNA binding. Both domains are important for Era function. Era is functionally able to compensate for deletion of RbfA, a cold-shock adaptation protein that is required for efficient processing of the 16S rRNA.


Pssm-ID: 206726 [Multi-domain]  Cd Length: 168  Bit Score: 40.91  E-value: 5.10e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 286 MKQGFefnIMVVGQSGLGKSTLINTLFKSKISrksvqPTSeeRIPKTieiksiT-HDIeeKGVRMK----LTVIDTPGfg 360
Cdd:cd04163    1 FKSGF---VAIIGRPNVGKSTLLNALVGQKIS-----IVS--PKPQT------TrNRI--RGIYTDddaqIIFVDTPG-- 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 361 dhinnencwqpIMKfindqYEKYLQEEVNINRKKRIPDtrVHCCLYFIPATgHSLRPLDIEFMKRLSKV-VNIVPVIAKA 439
Cdd:cd04163   61 -----------IHK-----PKKKLGERMVKAAWSALKD--VDLVLFVVDAS-EWIGEGDEFILELLKKSkTPVILVLNKI 121

                        170       180
                 ....*....|....*....|....*...
gi 164698498 440 DTLTLEERVhFKQRITADLLSNGIDVYP 467
Cdd:cd04163  122 DLVKDKEDL-LPLLEKLKELHPFAEIFP 148
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 64-265 5.21e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.24  E-value: 5.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498   64 SEPSARHVDSLSQRSPKASLRRVELSGPKAAEPVSRRTELSIDISSKQVENAGAIGPSRFGLKRAEVLGHKTP-----EP 138
Cdd:PHA03307  196 STPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRiweasGW 275

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  139 APRRTEITIVKPQESAHRRMEPPAskvPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLeP 218
Cdd:PHA03307  276 NGPSSRPGPASSSSSPRERSPSPS---PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRS-P 351

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 164698498  219 KPQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKA 265
Cdd:PHA03307  352 SPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRA 398
PHA03247 PHA03247
large tegument protein UL36; Provisional
 136-242 5.63e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 43.00  E-value: 5.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  136 PEPAPRRTeitiVKPQESAHRRMEPPASKVPEVPTAPATDAAPkRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSR 215
Cdd:PHA03247 2560 PPAAPDRS----VPPPRPAPRPSEPAVTSRARRPDAPPQSARP-RAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPA 2634

                          90       100
                  ....*....|....*....|....*..
gi 164698498  216 LEPKPQPPVAEATPRSQEATEAAPSCV 242
Cdd:PHA03247 2635 ANEPDPHPPPTVPPPERPRDDPAPGRV 2661
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 22-223 5.79e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 43.06  E-value: 5.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498    22 RSFEVEEVETPNSTPPRRVQTpllratvasstqkfqdlgvKNSEPSARHVDSLSQRSPKASLRRVELSGPKAA--EPVSR 99
Cdd:TIGR00927  259 PTFLTREVETDLLTSPRSVVE-------------------KNTLTTPRRVESNSSTNHWGLVGKNNLTTPQGTvlEHTPA 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498   100 RTELSIDISSKQvenagaigPSRFGLKRAEVLGHKTPEPAPRrTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAP- 178
Cdd:TIGR00927  320 TSEGQVTISIMT--------GSSPAETKASTAAWKIRNPLSR-TSAPAVRIASATFRGLEKNPSTAPSTPATPRVRAVLt 390

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 164698498   179 ---KRVEIQMPKPAeAPTAPSPAQT--LENSEPAP-VSQL---QSRLEPKPQPP 223
Cdd:TIGR00927  391 tqvHHCVVVKPAPA-VPTTPSPSLTtaLFPEAPSPsPSALppgQPDLHPKAEYP 443
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
34-255 6.16e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 42.91  E-value: 6.16e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  34 STPPRRVQTPLLRATVASSTQKFQDLGVKNSEPSARhvdslsQRSPKASLRRVELSGPKAAEPVSRRTELSIDISSKQVE 113
Cdd:PRK07003 374 ARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAA------LAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDA 447

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 114 NAGAIGPSRFGLKRAEVLGHKTPEPAPRrteitivkPQESAHRRMEPPASKVPEVPTAPATDAAPKRVeiqmpKPAEAPT 193
Cdd:PRK07003 448 PVPAKANARASADSRCDERDAQPPADSG--------SASAPASDAPPDAAFEPAPRAAAPSAATPAAV-----PDARAPA 514

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 164698498 194 APSpaqtlENSEPAPVSQLQSRLEPkPQPpvAEATPRSQEATEAAPscvgdmADTPRDAGLK 255
Cdd:PRK07003 515 AAS-----REDAPAAAAPPAPEARP-PTP--AAAAPAARAGGAAAA------LDVLRNAGMR 562
MJ1464 cd01859
An uncharacterized, circularly permuted subfamily of the Ras GTPases; This family represents ...
 273-358 6.78e-04

An uncharacterized, circularly permuted subfamily of the Ras GTPases; This family represents archaeal GTPase typified by the protein MJ1464 from Methanococcus jannaschii. The members of this family show a circular permutation of the GTPase signature motifs so that C-terminal strands 5, 6, and 7 (strands 6 contain the NKxD motif) are relocated to the N terminus.


Pssm-ID: 206752 [Multi-domain]  Cd Length: 157  Bit Score: 40.38  E-value: 6.78e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 273 GIDSILEQMRRKAMKqGFEFNIMVVGQSGLGKSTLINTLfkskiSRKSVQPTSeeRIPKtieIKSITHDIEEKGVRMKLT 352
Cdd:cd01859   82 GTRILRRTIKELAID-GKPVIVGVVGYPKVGKSSIINAL-----KGRHSASTS--PIPG---SPGYTKGIQLVRIDSKIY 150


                 ....*.
gi 164698498 353 VIDTPG 358
Cdd:cd01859  151 LIDTPG 156
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 137-271 7.17e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 42.39  E-value: 7.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 137 EPAPRRTEITIVKPQESAHRRMEPPASKVPEvptaPATDAAPKRVeiqmpKPAEAptAPSPAQTLENSEPAPVSQLQSRL 216
Cdd:PRK08691 393 KPQPRPEAETAQTPVQTASAAAMPSEGKTAG----PVSNQENNDV-----PPWED--APDEAQTAAGTAQTSAKSIQTAS 461

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 164698498 217 EP-KPQPPVAEATPRSQEATEAAPSCVGDMAD---TPRDAGLKQAPASRNEKAPVDFGY 271
Cdd:PRK08691 462 EAeTPPENQVSKNKAADNETDAPLSEVPSENPiqaTPNDEAVETETFAHEAPAEPFYGY 520
PLN03118 PLN03118
Rab family protein; Provisional
 292-358 7.90e-04

Rab family protein; Provisional


Pssm-ID: 215587 [Multi-domain]  Cd Length: 211  Bit Score: 41.19  E-value: 7.90e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 164698498 292 FNIMVVGQSGLGKSTLINTLFKSKIsrKSVQPTseerIPKTIEIKSITHDieekGVRMKLTVIDTPG 358
Cdd:PLN03118  15 FKILLIGDSGVGKSSLLVSFISSSV--EDLAPT----IGVDFKIKQLTVG----GKRLKLTIWDTAG 71
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 156-266 8.68e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 8.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 156 RRMEPPASKVPEVPTAPATDAAPkrveiqmPKPAEAPtAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEAT 235
Cdd:PRK07764 383 RRLGVAGGAGAPAAAAPSAAAAA-------PAAAPAP-AAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAP 454

                         90       100       110
                 ....*....|....*....|....*....|.
gi 164698498 236 EAAPSCVGDMADTPRDAGLKQAPASRNEKAP 266
Cdd:PRK07764 455 SPPPAAAPSAQPAPAPAAAPEPTAAPAPAPP 485
era TIGR00436
GTP-binding protein Era; Era is an essential GTPase in Escherichia coli and many other ...
 294-488 9.21e-04

GTP-binding protein Era; Era is an essential GTPase in Escherichia coli and many other bacteria. It plays a role in ribosome biogenesis. Few bacteria lack this protein. [Protein synthesis, Other]


Pssm-ID: 129528 [Multi-domain]  Cd Length: 270  Bit Score: 41.22  E-value: 9.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  294 IMVVGQSGLGKSTLINTLFKSKISRKSvqptseeRIPKTIEIKSITHDIEEKGvrmKLTVIDTPGFGD--HINNENCWQP 371
Cdd:TIGR00436   3 VAILGRPNVGKSTLLNQLHGQKISITS-------PKAQTTRNRISGIHTTGAS---QIIFIDTPGFHEkkHSLNRLMMKE 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  372 IMK---------FINDQYEKYLQEE--VNINRKKRIPdtrVHCCLYFIPATGHSLRPLDIEFMKRLSKVVNIVPViakaD 440
Cdd:TIGR00436  73 ARSaiggvdlilFVVDSDQWNGDGEfvLTKLQNLKRP---VVLTRNKLDNKFKDKLLPLIDKYAILEDFKDIVPI----S 145

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 164698498  441 TLTLEERVHFKQRITADlLSNGIDVYPQKEFDEDSEDRLVNEKFREMI 488
Cdd:TIGR00436 146 ALTGDNTSFLAAFIEVH-LPEGPFRYPEDYVTDQPDRFKISEIIREKI 192
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 135-266 9.79e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 42.16  E-value: 9.79e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 135 TPEPAPRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAPK-----RVEIQMPKPAEAPTAPSPAQTlenSEPAPV 209
Cdd:PRK07994 376 APAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSqllaaRQQLQRAQGATKAKKSEPAAA---SRARPV 452

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 164698498 210 SQLQSRLEPK-PQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKAP 266
Cdd:PRK07994 453 NSALERLASVrPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTP 510
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 114-276 1.03e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 42.08  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  114 NAGAIGPSRFGLKRAEVLGHKTPEPAPRR------TEITIVKPQESAHRRMEPPASKVPE------VPTAPATDAAPKRV 181
Cdd:PHA03307   56 VAGAAACDRFEPPTGPPPGPGTEAPANESrstptwSLSTLAPASPAREGSPTPPGPSSPDpppptpPPASPPPSPAPDLS 135

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  182 EI------------QMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQ-EATEAAPSCVGDM--- 245
Cdd:PHA03307  136 EMlrpvgspgpppaASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPpAAASPRPPRRSSPisa 215

                         170       180       190
                  ....*....|....*....|....*....|..
gi 164698498  246 -ADTPRDAGLKQAPASRNEKAPVDFGYVGIDS 276
Cdd:PHA03307  216 sASSPAPAPGRSAADDAGASSSDSSSSESSGC 247
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 135-257 1.05e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.90  E-value: 1.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 135 TPEPAPRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAA-----PKRVEIQMPKPAEAPTAPSPAQTLENSEPAPV 209
Cdd:PRK07764 684 APAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQgasapSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPA 763

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 164698498 210 SQlqSRLEPKPQPPVAEATPRSQEATEAAPScvgdMADTPRDAGLKQA 257
Cdd:PRK07764 764 PA--PAAAPAAAPPPSPPSEEEEMAEDDAPS----MDDEDRRDAEEVA 805
PHA03291 PHA03291
envelope glycoprotein I; Provisional
 116-238 1.09e-03

envelope glycoprotein I; Provisional


Pssm-ID: 223033 [Multi-domain]  Cd Length: 401  Bit Score: 41.48  E-value: 1.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 116 GAIGPSRFGLKRAEVLGHKTPEPAPR--RTEITIVKPQ-ESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAP 192
Cdd:PHA03291 152 GATNASLFPLGLAAFPAEGTLAAPPLgeGSADGSCDPAlPLSAPRLGPADVFVPATPRPTPRTTASPETTPTPSTTTSPP 231

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 164698498 193 TAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVA--EATPRSQEATEAA 238
Cdd:PHA03291 232 STTIPAPSTTIAAPQAGTTPEAEGTPAPPTPGGgeAPPANATPAPEAS 279
EF-G_bact cd04170
Elongation factor G (EF-G) family; Translocation is mediated by EF-G (also called translocase). ...
 293-361 1.31e-03

Elongation factor G (EF-G) family; Translocation is mediated by EF-G (also called translocase). The structure of EF-G closely resembles that of the complex between EF-Tu and tRNA. This is an example of molecular mimicry; a protein domain evolved so that it mimics the shape of a tRNA molecule. EF-G in the GTP form binds to the ribosome, primarily through the interaction of its EF-Tu-like domain with the 50S subunit. The binding of EF-G to the ribosome in this manner stimulates the GTPase activity of EF-G. On GTP hydrolysis, EF-G undergoes a conformational change that forces its arm deeper into the A site on the 30S subunit. To accommodate this domain, the peptidyl-tRNA in the A site moves to the P site, carrying the mRNA and the deacylated tRNA with it. The ribosome may be prepared for these rearrangements by the initial binding of EF-G as well. The dissociation of EF-G leaves the ribosome ready to accept the next aminoacyl-tRNA into the A site. This group contains only bacterial members.


Pssm-ID: 206733 [Multi-domain]  Cd Length: 268  Bit Score: 41.04  E-value: 1.31e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 164698498 293 NIMVVGQSGLGKSTLINT-LFKSK-ISRK-------SVQPTSEERIPKTIEIKSITHDIEEKGVrmKLTVIDTPGFGD 361
Cdd:cd04170    1 NIALVGHSGSGKTTLAEAlLYATGaIDRLgrvedgnTVSDYDPEEKKRKMSIETSVAPLEWNGH--KINLIDTPGYAD 76
RsgA COG1162
Ribosome biogenesis GTPase RsgA [Translation, ribosomal structure and biogenesis];
273-359 1.35e-03

Ribosome biogenesis GTPase RsgA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440776 [Multi-domain]  Cd Length: 300  Bit Score: 40.87  E-value: 1.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 273 GIDSILEQMRRKamkqgfefNIMVVGQSGLGKSTLINTLFKskisrKSVQPTSE--ERIPK----TieiksiTH----DI 342
Cdd:COG1162  156 GLDELRELLKGK--------TSVLVGQSGVGKSTLINALLP-----DADLATGEisEKLGRgrhtT------THaelyPL 216

                         90
                 ....*....|....*..
gi 164698498 343 EEKGVrmkltVIDTPGF 359
Cdd:COG1162  217 PGGGW-----LIDTPGF 228
AIG1 cd01852
AvrRpt2-Induced Gene 1 (AIG1); This group represents Arabidoposis protein AIG1 ...
 293-361 1.54e-03

AvrRpt2-Induced Gene 1 (AIG1); This group represents Arabidoposis protein AIG1 (avrRpt2-induced gene 1) that appears to be involved in plant resistance to bacteria. The Arabidopsis disease resistance gene RPS2 is involved in recognition of bacterial pathogens carrying the avirulence gene avrRpt2. AIG1 exhibits RPS2- and avrRpt1-dependent induction early after infection with Pseudomonas syringae carrying avrRpt2. This subfamily also includes IAN-4 protein, which has GTP-binding activity and shares sequence homology with a novel family of putative GTP-binding proteins: the immuno-associated nucleotide (IAN) family. The evolutionary conservation of the IAN family provides a unique example of a plant pathogen response gene conserved in animals. The IAN/IMAP subfamily has been proposed to regulate apoptosis in vertebrates and angiosperm plants, particularly in relation to cancer, diabetes, and infections. The human IAN genes were renamed GIMAP (GTPase of the immunity associated proteins).


Pssm-ID: 206651 [Multi-domain]  Cd Length: 201  Bit Score: 40.21  E-value: 1.54e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 164698498 293 NIMVVGQSGLGKSTLINTL-----FKSKISRKSVqptseeripkTIEIKSITHDIEEKgvrmKLTVIDTPGFGD 361
Cdd:cd01852    2 RLVLVGKTGNGKSATGNTIlgrkvFESKLSASGV----------TKTCQKESAVWDGR----RVNVIDTPGLFD 61
PHA03369 PHA03369
capsid maturational protease; Provisional
 148-247 1.59e-03

capsid maturational protease; Provisional


Pssm-ID: 223061 [Multi-domain]  Cd Length: 663  Bit Score: 41.52  E-value: 1.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 148 VKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVE-IQMPKPAEAPTAPSPAQTLENSEPAPVSQLQsrlepkPQPPVAE 226
Cdd:PHA03369 354 TAPSRVLAAAAKVAVIAAPQTHTGPADRQRPQRPDgIPYSVPARSPMTAYPPVPQFCGDPGLVSPYN------PQSPGTS 427

                         90       100
                 ....*....|....*....|.
gi 164698498 227 ATPRSQEATEAAPSCVGDMAD 247
Cdd:PHA03369 428 YGPEPVGPVPPQPTNPYVMPI 448
RsgA_GTPase pfam03193
RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are ...
 296-359 1.59e-03

RsgA GTPase; RsgA (also known as EngC and YjeQ) represents a protein family whose members are broadly conserved in bacteria and are indispensable for growth. The GTPase domain of RsgA is very similar to several P-loop GTPases, but differs in having a circular permutation of the GTPase structure described by a G4-G1-G3 pattern.


Pssm-ID: 427191 [Multi-domain]  Cd Length: 174  Bit Score: 39.83  E-value: 1.59e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 164698498  296 VVGQSGLGKSTLINTLfkskisrksvQPTSEERipktieiksiTHDIEEKGVRMKLT--------------VIDTPGF 359
Cdd:pfam03193 111 LAGQSGVGKSTLLNAL----------LPELDLR----------TGEISEKLGRGRHTtthvelfplpggglLIDTPGF 168
flhF PRK06995
flagellar biosynthesis protein FlhF;
147-256 1.63e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 41.11  E-value: 1.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 147 IVKPQESAHRRMEPPASKVP---EVPTAPATDAAPKRVEiqMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPP 223
Cdd:PRK06995  51 LAPPAAAAPAAAQPPPAAAPaavSRPAAPAAEPAPWLVE--HAKRLTAQREQLVARAAAPAAPEAQAPAAPAERAAAENA 128

                         90       100       110
                 ....*....|....*....|....*....|...
gi 164698498 224 VAEATPRSQEATEAAPScvGDMADTPRDAGLKQ 256
Cdd:PRK06995 129 ARRLARAAAAAPRPRVP--ADAAAAVADAVKAR 159
PHA03378 PHA03378
EBNA-3B; Provisional
 133-320 1.64e-03

EBNA-3B; Provisional


Pssm-ID: 223065 [Multi-domain]  Cd Length: 991  Bit Score: 41.59  E-value: 1.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 133 HKTPEPAPRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQL 212
Cdd:PHA03378 652 HQPPQVEITPYKPTWTQIGHIPYQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAP 731

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 213 QSRLEPKPQP---PVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPAS--------RNEKAPVDFGYVGIDSILEQM 281
Cdd:PHA03378 732 GRARPPAAAPgraRPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAppapqqrpRGAPTPQPPPQAGPTSMQLMP 811

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 164698498 282 RRKAMKQGFEFNIMVVGQSGLGKSTLINTLFKSKISRKS 320
Cdd:PHA03378 812 RAAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAALERQA 850
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 135-266 1.74e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.51  E-value: 1.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 135 TPEPAPRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAPkrveiqmPKPAEAPTAPSPAQTLENSEPAPVSQLQS 214
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAA-------AAPAEASAAPAPGVAAPEHHPKHVAVPDA 662

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 164698498 215 RLEPKPQP-PVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKAP 266
Cdd:PRK07764 663 SDGGDGWPaKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQAD 715
PspC_subgroup_1 NF033838
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ...
 149-231 1.76e-03

pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.


Pssm-ID: 468201 [Multi-domain]  Cd Length: 684  Bit Score: 41.15  E-value: 1.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 149 KPQESAHRRM--EPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPA--QTLEN------SEPAPVSQLQSrleP 218
Cdd:NF033838 397 KAEEEAKRKAaeEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAEQPKAEKPAdqQAEEDyarrseEEYNRLTQQQP---P 473

                         90
                 ....*....|...
gi 164698498 219 KPQPPVAEATPRS 231
Cdd:NF033838 474 KTEKPAQPSTPKT 486
PRK00098 PRK00098
GTPase RsgA; Reviewed
 276-366 2.02e-03

GTPase RsgA; Reviewed


Pssm-ID: 234631 [Multi-domain]  Cd Length: 298  Bit Score: 40.57  E-value: 2.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 276 SILEQMRRKAMKQGFEFNI-MVVGQSGLGKSTLINTLfkskisrksvqptseerIPKtIEIKsiTHDIEEKGVRMKLT-- 352
Cdd:PRK00098 148 SAKEGEGLDELKPLLAGKVtVLAGQSGVGKSTLLNAL-----------------APD-LELK--TGEISEALGRGKHTtt 207

                         90       100       110
                 ....*....|....*....|....*....|
gi 164698498 353 ------------VIDTPGFG----DHINNE 366
Cdd:PRK00098 208 hvelydlpggglLIDTPGFSsfglHDLEAE 237
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 160-259 2.55e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.74  E-value: 2.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 160 PPASKVPEVPTAPATDAAPkrveiQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQ-PPVAEATPRSQEATEAA 238
Cdd:PRK07764 399 PSAAAAAPAAAPAPAAAAP-----AAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSpPPAAAPSAQPAPAPAAA 473

                         90       100
                 ....*....|....*....|.
gi 164698498 239 PSCVGDMADTPRDAGLKQAPA 259
Cdd:PRK07764 474 PEPTAAPAPAPPAAPAPAAAP 494
PRK11633 PRK11633
cell division protein DedD; Provisional
 149-272 2.60e-03

cell division protein DedD; Provisional


Pssm-ID: 236940 [Multi-domain]  Cd Length: 226  Bit Score: 39.60  E-value: 2.60e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 149 KPQESAHRRMEPPASkvPEVPTAPATDAAPkrvEIQMPKPAEAPTAPSPAQTlENSEPAPVSQLQSRLEPKPQPPVAEAt 228
Cdd:PRK11633  46 KPGDRDEPDMMPAAT--QALPTQPPEGAAE---AVRAGDAAAPSLDPATVAP-PNTPVEPEPAPVEPPKPKPVEKPKPK- 118

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 164698498 229 PRSQEATEAAPscvgdmadTPRDAglkQAPASRNEKAPVDFGYV 272
Cdd:PRK11633 119 PKPQQKVEAPP--------APKPE---PKPVVEEKAAPTGKAYV 151
PHA03247 PHA03247
large tegument protein UL36; Provisional
 30-256 3.27e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.69  E-value: 3.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498   30 ETPNSTPPRRVQTPLLRATVASSTQkfqdlgvknSEPSARHVDSLSQRSPKASLRRVELSGPKAAEPVSRRTELSIDISS 109
Cdd:PHA03247 2818 LPPAASPAGPLPPPTSAQPTAPPPP---------PGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLAR 2888

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  110 KQVEnagaigpsrfglKRAEVLGHKTPEPAPRRTEITIVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPA 189
Cdd:PHA03247 2889 PAVS------------RSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPS 2956

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  190 EAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEA---TEAAPSCVGDMADTPRDAGLKQ 256
Cdd:PHA03247 2957 GAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPPLTGHSLsrvSSWASSLALHEETDPPPVSLKQ 3026
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 134-229 3.35e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 40.44  E-value: 3.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 134 KTPEPA----PRRTEITIVKPQ-----ESAHRRMEPPASKVPEVPTAPATDAAPKRVE-IQMPKPAEAPTAP-SPAQTLE 202
Cdd:PTZ00449 559 KKPGPAkehkPSKIPTLSKKPEfpkdpKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPElLDIPKSPKRPESPkSPKRPPP 638

                         90       100
                 ....*....|....*....|....*...
gi 164698498 203 NSEPAPVSQLQSRLEPK-PQPPVAEATP 229
Cdd:PTZ00449 639 PQRPSSPERPEGPKIIKsPKPPKSPKPP 666
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 159-269 3.45e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 40.47  E-value: 3.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 159 EPPASKVPEVPTAPATDAAPKRVeiqMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPPVAEAtpRSQEATEAA 238
Cdd:PRK14951 388 APAAAPVAQAAAAPAPAAAPAAA---ASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPA--QAAPETVAI 462

                         90       100       110
                 ....*....|....*....|....*....|....
gi 164698498 239 PSCVG---DMADTPRDAGLKQAPASRNEKAPVDF 269
Cdd:PRK14951 463 PVRVApepAVASAAPAPAAAPAAARLTPTEEGDV 496
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 134-268 3.88e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 40.23  E-value: 3.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 134 KTPEPAPrrteitiVKPQESAHRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQ 213
Cdd:PRK07994 362 AAPLPEP-------EVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQG 434

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 164698498 214 SRLEPKPQPPVAEATPRSQEATEAAPScVGDMADTPRDAGLKQAPASRNEKAPVD 268
Cdd:PRK07994 435 ATKAKKSEPAAASRARPVNSALERLAS-VRPAPSALEKAPAKKEAYRWKATNPVE 488
SepH NF040712
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ...
 136-267 4.01e-03

septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.


Pssm-ID: 468676 [Multi-domain]  Cd Length: 346  Bit Score: 39.75  E-value: 4.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 136 PEPAPRRTEITIVKPQESAHRRmepPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSR 215
Cdd:NF040712 205 LAREPADARPEEVEPAPAAEGA---PATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPP 281

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 164698498 216 LEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKAPV 267
Cdd:NF040712 282 APGAAETPEAAEPPAPAPAAPAAPAAPEAEEPARPEPPPAPKPKRRRRRASV 333
COG5373 COG5373
Uncharacterized membrane protein [Function unknown];
141-208 4.41e-03

Uncharacterized membrane protein [Function unknown];


Pssm-ID: 444140 [Multi-domain]  Cd Length: 854  Bit Score: 39.98  E-value: 4.41e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 164698498 141 RRTEITIVKPQESAHRRMEP-PASKVPEVPTAPATDAAPkrVEIQMPKPAEAPTAPSPAQTLENSEPAP 208
Cdd:COG5373   31 EELEAELAEAAEAASAPAEPePEAAAAATAAAPEAAPAP--VPEAPAAPPAAAEAPAPAAAAPPAEAEP 97
PHA03247 PHA03247
large tegument protein UL36; Provisional
 32-223 4.48e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 4.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498   32 PNSTPPRRvqtpLLRATVASSTQKFQDL-GVKNSEPSARHVDSLSQRSPKASLRRVELSGPKAAEPVSRRTELSIDISSK 110
Cdd:PHA03247 2775 PAAGPPRR----LTRPAVASLSESRESLpSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSL 2850

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  111 QVEnaGAIGP----SRFGLKRAEVLGHKTPEPAPRRTeitIVKPQESahRRMEPPASKVPEVPTAPATDAAPKRVEIQMP 186
Cdd:PHA03247 2851 PLG--GSVAPggdvRRRPPSRSPAAKPAAPARPPVRR---LARPAVS--RSTESFALPPDQPERPPQPQAPPPPQPQPQP 2923

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 164698498  187 KPAEAPTAPSPAQTLENSEPAPVSQLQSRLEPKPQPP 223
Cdd:PHA03247 2924 PPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVP 2960
DedD COG3147
Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, ...
 161-229 4.55e-03

Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442381 [Multi-domain]  Cd Length: 140  Bit Score: 37.83  E-value: 4.55e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 164698498 161 PASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQlqsrlePKPQPPVAEATP 229
Cdd:COG3147    1 PAEEAAAAPAAAAAPAAPAAAAAPAPAAAAAAAAPKPAAKPAAPKPAAAAA------AAPAAKAAAPAG 63
PRK10905 PRK10905
cell division protein DamX; Validated
 143-260 4.87e-03

cell division protein DamX; Validated


Pssm-ID: 236792 [Multi-domain]  Cd Length: 328  Bit Score: 39.54  E-value: 4.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 143 TEITIVKPQESAHRRMEPPASKVPEvpTAPATDAAPKRVEIQMPKPAEAPTAP--SPAQTLENSEPA------PVSQLQS 214
Cdd:PRK10905 125 TEPATVAPVRNGNASRQTAKTQTAE--RPATTRPARKQAVIEPKKPQATAKTEpkPVAQTPKRTEPAapvastKAPAATS 202

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 164698498 215 RLEPKPQPPVAEATPRSQEATEAAPSCVGDMADtprDAG-LKQAPAS 260
Cdd:PRK10905 203 TPAPKETATTAPVQTASPAQTTATPAAGGKTAG---NVGsLKSAPSS 246
PHA03247 PHA03247
large tegument protein UL36; Provisional
 140-266 5.01e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.92  E-value: 5.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  140 PRRTEITIVKPQESAH-RRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQLQSRLEP 218
Cdd:PHA03247 2664 PRRARRLGRAAQASSPpQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPA 2743

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 164698498  219 KPQPPVAEATPRSQE-----ATEAAPSCVGDMADTPRDAGLKQAPASRNEKAP 266
Cdd:PHA03247 2744 VPAGPATPGGPARPArppttAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRE 2796
GTPase_YsxC TIGR03598
ribosome biogenesis GTP-binding protein YsxC/EngB; Members of this protein family are a GTPase ...
 297-468 5.70e-03

ribosome biogenesis GTP-binding protein YsxC/EngB; Members of this protein family are a GTPase associated with ribosome biogenesis, typified by YsxC from Bacillus subutilis. The family is widely but not universally distributed among bacteria. Members commonly are called EngB based on homology to EngA, one of several other GTPases of ribosome biogenesis. Cutoffs as set find essentially all bacterial members, but also identify large numbers of eukaryotic (probably organellar) sequences. This protein is found in about 80 percent of bacterial genomes. [Protein synthesis, Other]


Pssm-ID: 274670 [Multi-domain]  Cd Length: 179  Bit Score: 38.22  E-value: 5.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  297 VGQSGLGKSTLINTLFKSK-ISRKSVQPTseeripKTIEIksITHDIEEkgvrmKLTVIDTPGFG-------DHINnenc 368
Cdd:TIGR03598  24 AGRSNVGKSSLINALTNRKkLARTSKTPG------RTQLI--NFFEVND-----GFRLVDLPGYGyakvskeEKEK---- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  369 WQPIMkfindqyEKYLQEEVNInrkkripdtrvhCCLYFIPATGHSLRPLDIEFMKRL-SKVVNIVPVIAKADTLTLEER 447
Cdd:TIGR03598  87 WQKLI-------EEYLEKRENL------------KGVVLLMDIRHPLKELDLEMIEWLrERGIPVLIVLTKADKLKKSEL 147

                         170       180
                  ....*....|....*....|.
gi 164698498  448 VHFKQRITADLLSNGIDVYPQ 468
Cdd:TIGR03598 148 NKQLKKIKKALKKDADDPSVQ 168
DUF3729 pfam12526
Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins ...
 150-236 5.94e-03

Protein of unknown function (DUF3729); This family of proteins is found in viruses. Proteins in this family are typically between 145 and 1707 amino acids in length. The family is found in association with pfam01443, pfam01661, pfam05417, pfam01660, pfam00978. There is a single completely conserved residue L that may be functionally important.


Pssm-ID: 372164 [Multi-domain]  Cd Length: 115  Bit Score: 36.98  E-value: 5.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  150 PQESAHRRMEPPaskvPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPvsqLQSRLEPKpqPPVAEATP 229
Cdd:pfam12526  31 PPESAHPDPPPP----VGDPRPPVVDTPPPVSAVWVLPPPSEPAAPEPDLVPPVTGPAG---PPSPLAPP--APAQKPPL 101


                  ....*..
gi 164698498  230 RSQEATE 236
Cdd:pfam12526 102 PPPRPQR 108
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 155-271 6.38e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 39.46  E-value: 6.38e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 155 HRRMEPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSEPAPVSQ--LQSRLEPKPQPPVAEATPRSQ 232
Cdd:PRK07994 360 HPAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPetTSQLLAARQQLQRAQGATKAK 439

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 164698498 233 EATEAAPSCVGDMAD-TPRDAGLKQAPASRNEKAPVDFGY 271
Cdd:PRK07994 440 KSEPAAASRARPVNSaLERLASVRPAPSALEKAPAKKEAY 479
PRK10905 PRK10905
cell division protein DamX; Validated
 135-214 7.42e-03

cell division protein DamX; Validated


Pssm-ID: 236792 [Multi-domain]  Cd Length: 328  Bit Score: 38.77  E-value: 7.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 135 TPEPAPRRTEITIVKPQESAHRRMEPPASKV----PEVPTAPA------TDAAPKRVEIQMPKPAEAPTAPSPAQTLENS 204
Cdd:PRK10905 153 TTRPARKQAVIEPKKPQATAKTEPKPVAQTPkrtePAAPVASTkapaatSTPAPKETATTAPVQTASPAQTTATPAAGGK 232

                         90
                 ....*....|
gi 164698498 205 EPAPVSQLQS 214
Cdd:PRK10905 233 TAGNVGSLKS 242
PRK11901 PRK11901
hypothetical protein; Reviewed
 169-261 7.95e-03

hypothetical protein; Reviewed


Pssm-ID: 237015 [Multi-domain]  Cd Length: 327  Bit Score: 38.51  E-value: 7.95e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 169 PTAPATDAAPKrveiQMPKPAEAPTAPSPAQTLENSEPAPVsqlqsrlePKPQPPVA-EATPRSQEATEAAPScvgdmad 247
Cdd:PRK11901 175 PTAPATVAPSK----GAKVPATAETHPTPPQKPATKKPAVN--------HHKTATVAvPPATSGKPKSGAASA------- 235

                         90
                 ....*....|....
gi 164698498 248 tprdAGLKQAPASR 261
Cdd:PRK11901 236 ----RALSSAPASH 245
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 159-259 8.19e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.20  E-value: 8.19e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 159 EPPASKVPEVPTAPATDAAPKRVEIQMPKPAEAPTAPSPAQTLENSePAPVSQLQSRLEPKPQPPVAEATPRSQEATEAA 238
Cdd:PRK07764 410 PAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPS-PPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAP 488

                         90       100
                 ....*....|....*....|.
gi 164698498 239 PScvGDMADTPRDAGLKQAPA 259
Cdd:PRK07764 489 AP--AAAPAAPAAPAAPAGAD 507
DamX COG3266
Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell ...
 36-265 8.70e-03

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442497 [Multi-domain]  Cd Length: 455  Bit Score: 38.68  E-value: 8.70e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  36 PPRRVQTPLLRATVASSTQKFQDLGVKNSEPSARHVDSLSQRSPKASLRRVEL--SGPKAAEPVSRRTELSIDISSKQVE 113
Cdd:COG3266  156 PLLEEQLLLLALQDIQGTLQALGAVAALLGLRKAEEALALRAGSAAADALALLllLLASALGEAVAAAAELAALALLAAG 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 114 NAGAIGPSRFGLKRAEVLGHKTPEPAPRRTEITIVKPQESAHRRMEPPASKVP--EVPTAPATDAAPkrveiQMPKPAEA 191
Cdd:COG3266  236 AAEVLTARLVLLLLIIGSALKAPSQASSASAPATTSLGEQQEVSLPPAVAAQPaaAAAAQPSAVALP-----AAPAAAAA 310

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 164698498 192 PTAPSPAQTLENSEPAPVS-QLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKA 265
Cdd:COG3266  311 AAAPAEAAAPQPTAAKPVVtETAAPAAPAPEAAAAAAAPAAPAVAKKLAADEQWLASQPASHYTLQLLGASSEAA 385
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 136-276 8.77e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 39.00  E-value: 8.77e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498  136 PEPAPRRTEI--TIVKPQESAHRRMEPPASKVPEVPTAPAT--------DAAPKRVEIQMPKPAEAPTAPSPAQTLENSE 205
Cdd:PHA03307  128 PSPAPDLSEMlrPVGSPGPPPAASPPAAGASPAAVASDAASsrqaalplSSPEETARAPSSPPAEPPPSTPPAAASPRPP 207

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 164698498  206 PAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMADTPRDAGLKQAPASRNEKAPVDFGYVGIDS 276
Cdd:PHA03307  208 RRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGP 278
flhF PRK06995
flagellar biosynthesis protein FlhF;
168-283 9.94e-03

flagellar biosynthesis protein FlhF;


Pssm-ID: 235904 [Multi-domain]  Cd Length: 484  Bit Score: 38.79  E-value: 9.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 164698498 168 VPTAPATDAAPkrveiqMPKPAEAPTAPS-PAQTLENSEPAPVSQLQSRLEPKPQPPVAEATPRSQEATEAAPSCVGDMA 246
Cdd:PRK06995  52 APPAAAAPAAA------QPPPAAAPAAVSrPAAPAAEPAPWLVEHAKRLTAQREQLVARAAAPAAPEAQAPAAPAERAAA 125

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 164698498 247 DTPRDAGLKQAPASRNEKAPVDFGYVGIDSILEQMRR 283
Cdd:PRK06995 126 ENAARRLARAAAAAPRPRVPADAAAAVADAVKARIER 162
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH