NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|156231040|ref|NP_001095888|]
View 

kininogen-1 isoform 2 precursor [Rattus norvegicus]

Protein Classification

CY domain-containing protein( domain architecture ID 11077421)

CY domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 264-371 1.38e-31

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


:

Pssm-ID: 214484  Cd Length: 107  Bit Score: 116.37  E-value: 1.38e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040   264 CPGCPRNIPVDSPELKEALGHSIAQLNAENNHTFYFKIDTVKKATSQVVAGTKYVIEFIARETKCSKESnaELTADCETK 343
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231040   344 RLGQsLNCNANVYMRPWENK-VVPTVKCK 371
Cdd:smart00043  80 DQGE-KFCTAKVWEKPWENKiKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 144-238 3.31e-24

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 95.86  E-value: 3.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040  144 GCMHPISVDSPELGPVLKHAVEHFNNNTkHTHLFALGEVKSADRQVVAGMNYQIIYSIVQTNCSKedFPSLHEDCVPLPS 223
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 156231040  224 GDDGECKGNAFVDIH 238
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 29-116 1.12e-17

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


:

Pssm-ID: 425431  Cd Length: 92  Bit Score: 77.76  E-value: 1.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040   29 NDESLFQAVDTALKKYNAGLkSGNQFVLYQVTEGTKKDGSKTFYSFKYQIKEGNCSVqSGFAWQDCDFKDaeEAATGECT 108
Cdd:pfam00031   9 NSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKWLGLCS 84


                  ....*...
gi 156231040  109 ATLEKRRN 116
Cdd:pfam00031  85 AQVYKVPW 92
 
Name Accession Description Interval E-value
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 264-371 1.38e-31

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 116.37  E-value: 1.38e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040   264 CPGCPRNIPVDSPELKEALGHSIAQLNAENNHTFYFKIDTVKKATSQVVAGTKYVIEFIARETKCSKESnaELTADCETK 343
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231040   344 RLGQsLNCNANVYMRPWENK-VVPTVKCK 371
Cdd:smart00043  80 DQGE-KFCTAKVWEKPWENKiKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 266-360 5.37e-30

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 111.66  E-value: 5.37e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040  266 GCPRNIPVDSPELKEALGHSIAQLNAENnHTFYFKIDTVKKATSQVVAGTKYVIEFIARETKCSKesNAELTADCETKRL 345
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 156231040  346 GQSLNCNANVYMRPW 360
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 266-370 1.24e-29

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 111.03  E-value: 1.24e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040 266 GCPRNIPVDSPELKEALGHSIAQLNAENNHTfYFKIDTVKKATSQVVAGTKYVIEFIARETKCSKESNAELTADCETKRL 345
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 156231040 346 GQSLNCNANVYMRPWEN-KVVPTVKC 370
Cdd:cd00042   80 GKKKFCTAKVWEKPWENfKELLSFKC 105
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 144-238 3.31e-24

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 95.86  E-value: 3.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040  144 GCMHPISVDSPELGPVLKHAVEHFNNNTkHTHLFALGEVKSADRQVVAGMNYQIIYSIVQTNCSKedFPSLHEDCVPLPS 223
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 156231040  224 GDDGECKGNAFVDIH 238
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 144-238 1.08e-23

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 94.85  E-value: 1.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040 144 GCMHPISVDSPELGPVLKHAVEHFNNNTKHTHlFALGEVKSADRQVVAGMNYQIIYSIVQTNCSKEDFPSLHEDCVPLPS 223
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90
                 ....*....|....*
gi 156231040 224 GDDGECKGNAFVDIH 238
Cdd:cd00042   80 GKKKFCTAKVWEKPW 94
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 142-249 1.59e-23

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 94.42  E-value: 1.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040   142 CLGCMHPISVDSPELGPVLKHAVEHFNNNTKHTHLFALGEVKSADRQVVAGMNYQIIYSIVQTNCSKEDfpSLHEDCVPL 221
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231040   222 PSGdDGECKGNAF-VDIHKTIAGFSDSCE 249
Cdd:smart00043  80 DQG-EKFCTAKVWeKPWENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 29-116 1.12e-17

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 77.76  E-value: 1.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040   29 NDESLFQAVDTALKKYNAGLkSGNQFVLYQVTEGTKKDGSKTFYSFKYQIKEGNCSVqSGFAWQDCDFKDaeEAATGECT 108
Cdd:pfam00031   9 NSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKWLGLCS 84


                  ....*...
gi 156231040  109 ATLEKRRN 116
Cdd:pfam00031  85 AQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 1.11e-14

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 69.76  E-value: 1.11e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040    23 AQEMDCNDESLFQAVDTALKKYNAglKSGNQFVLY--QVTEGTKKDGSKTFYSFKYQIKEGNCSVQSGFaWQDCDFKDAE 100
Cdd:smart00043   6 PSDVPPNDPEVQEAADFAVAEYNK--KSNDKYELRviKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQG 82

                           90       100
                   ....*....|....*....|....*..
gi 156231040   101 EaatGECTATL-EKRRNNKFSIATQIC 126
Cdd:smart00043  83 E---KFCTAKVwEKPWENKIKLVEFKC 106
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 24-110 7.10e-05

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 41.69  E-value: 7.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040  24 QEMDCNDESLFQAVDTALKKYNAGLKSGNqFVLYQVTEGTKKDGSKTFYSFKYQIKEGNCSVQSGFAWQdCDFKDAEEAA 103
Cdd:cd00042    4 SDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDC-PDCKLLEEGK 81


                 ....*..
gi 156231040 104 TGECTAT 110
Cdd:cd00042   82 KKFCTAK 88
 
Name Accession Description Interval E-value
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 264-371 1.38e-31

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 116.37  E-value: 1.38e-31
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040   264 CPGCPRNIPVDSPELKEALGHSIAQLNAENNHTFYFKIDTVKKATSQVVAGTKYVIEFIARETKCSKESnaELTADCETK 343
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231040   344 RLGQsLNCNANVYMRPWENK-VVPTVKCK 371
Cdd:smart00043  80 DQGE-KFCTAKVWEKPWENKiKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 266-360 5.37e-30

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 111.66  E-value: 5.37e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040  266 GCPRNIPVDSPELKEALGHSIAQLNAENnHTFYFKIDTVKKATSQVVAGTKYVIEFIARETKCSKesNAELTADCETKRL 345
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 156231040  346 GQSLNCNANVYMRPW 360
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 266-370 1.24e-29

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 111.03  E-value: 1.24e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040 266 GCPRNIPVDSPELKEALGHSIAQLNAENNHTfYFKIDTVKKATSQVVAGTKYVIEFIARETKCSKESNAELTADCETKRL 345
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90       100
                 ....*....|....*....|....*.
gi 156231040 346 GQSLNCNANVYMRPWEN-KVVPTVKC 370
Cdd:cd00042   80 GKKKFCTAKVWEKPWENfKELLSFKC 105
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 144-238 3.31e-24

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 95.86  E-value: 3.31e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040  144 GCMHPISVDSPELGPVLKHAVEHFNNNTkHTHLFALGEVKSADRQVVAGMNYQIIYSIVQTNCSKedFPSLHEDCVPLPS 223
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 156231040  224 GDDGECKGNAFVDIH 238
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 144-238 1.08e-23

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 94.85  E-value: 1.08e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040 144 GCMHPISVDSPELGPVLKHAVEHFNNNTKHTHlFALGEVKSADRQVVAGMNYQIIYSIVQTNCSKEDFPSLHEDCVPLPS 223
Cdd:cd00042    1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                         90
                 ....*....|....*
gi 156231040 224 GDDGECKGNAFVDIH 238
Cdd:cd00042   80 GKKKFCTAKVWEKPW 94
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 142-249 1.59e-23

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 94.42  E-value: 1.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040   142 CLGCMHPISVDSPELGPVLKHAVEHFNNNTKHTHLFALGEVKSADRQVVAGMNYQIIYSIVQTNCSKEDfpSLHEDCVPL 221
Cdd:smart00043   2 CLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPFL 79

                           90       100
                   ....*....|....*....|....*....
gi 156231040   222 PSGdDGECKGNAF-VDIHKTIAGFSDSCE 249
Cdd:smart00043  80 DQG-EKFCTAKVWeKPWENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 29-116 1.12e-17

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 77.76  E-value: 1.12e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040   29 NDESLFQAVDTALKKYNAGLkSGNQFVLYQVTEGTKKDGSKTFYSFKYQIKEGNCSVqSGFAWQDCDFKDaeEAATGECT 108
Cdd:pfam00031   9 NSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--EKWLGLCS 84


                  ....*...
gi 156231040  109 ATLEKRRN 116
Cdd:pfam00031  85 AQVYKVPW 92
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 23-126 1.11e-14

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 69.76  E-value: 1.11e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040    23 AQEMDCNDESLFQAVDTALKKYNAglKSGNQFVLY--QVTEGTKKDGSKTFYSFKYQIKEGNCSVQSGFaWQDCDFKDAE 100
Cdd:smart00043   6 PSDVPPNDPEVQEAADFAVAEYNK--KSNDKYELRviKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQG 82

                           90       100
                   ....*....|....*....|....*..
gi 156231040   101 EaatGECTATL-EKRRNNKFSIATQIC 126
Cdd:smart00043  83 E---KFCTAKVwEKPWENKIKLVEFKC 106
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 24-110 7.10e-05

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 41.69  E-value: 7.10e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 156231040  24 QEMDCNDESLFQAVDTALKKYNAGLKSGNqFVLYQVTEGTKKDGSKTFYSFKYQIKEGNCSVQSGFAWQdCDFKDAEEAA 103
Cdd:cd00042    4 SDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDC-PDCKLLEEGK 81


                 ....*..
gi 156231040 104 TGECTAT 110
Cdd:cd00042   82 KKFCTAK 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH