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Conserved domains on  [gi|149393138|ref|NP_001092264|]
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FHF complex subunit HOOK-interacting protein 1B isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RAI16-like pfam10257
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a ...
97-426 1.23e-110

Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a family of proteins described as retinoic acid-induced protein 16-like proteins. The exact function is not known. The proteins are found from worms to humans.


:

Pssm-ID: 370927  Cd Length: 357  Bit Score: 345.85  E-value: 1.23e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138   97 LEFALHEDLLTRVLTWQLQwdELGDGVeerRAEQLKLFEMLVSEARQPLLRHGPVREALLTLLDACGRPVPssPALDEGL 176
Cdd:pfam10257   2 LEYLLQHKILETLCTLGKA--DYPPGM---KQEVLKFYNKLLSHERQPLLHHINVHRPLQKLLRSCGEPVG--SDVEKEL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  177 VLLLSQLCVCVAQEPSLLEFFLQP----------------PPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMAL 240
Cdd:pfam10257  75 VQLLFGLCVKLRQDPSLLNFFFENksdqqraellvnpsveFAGATGKEDFNLFSLLLPLVHREGRLGVFAREGLLLLMSL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  241 SAGSPTVGRYIADHSYFCPVLATGLSALYSSLPRKIE---VPGDDW---HCLRREDWLGVP---ALALFMSSLEFCNAVI 311
Cdd:pfam10257 155 ASRSPTLATYLIESSDLCPLLATGLGALYSLLPTSLPaptISSIDWrldHSIAPEDLATFPgkrALDSFLSWLDFCNDLI 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  312 QVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLR-------TFLRFLLLHRHDTHTI 384
Cdd:pfam10257 235 QVAHSEVADALLDAIYEGFLVPVLYPSLLQTSEGSILAVTAYLDRILRSITSPALLQeflsfllGEEKSPETSDDDGHPL 314
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 149393138  385 LDTLVARIGSNS-RLCMVSLSLFRTLLNLSCEDVLLQLVLRYL 426
Cdd:pfam10257 315 RDTLIERCNHLSdELSIVTLRLFETLLQLPCEDILLDLVLRNL 357
DUF5917 pfam19314
Family of unknown function (DUF5917); This short presumed domain is found close to the ...
738-831 4.18e-40

Family of unknown function (DUF5917); This short presumed domain is found close to the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins.


:

Pssm-ID: 466037  Cd Length: 94  Bit Score: 142.71  E-value: 4.18e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  738 TGPFMAVLFAKLENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIENFAASQEDF 817
Cdd:pfam19314   1 EGPFLRMLFNKLENLLSQSYEVNLQLTGVISRLASYPQPLLHSYLLNPSLPLQPSVRSLYTVLSSLKEEIEERAASIPDF 80
                          90
                  ....*....|....
gi 149393138  818 PALLSKAKKYLIAR 831
Cdd:pfam19314  81 DALLRRARKRLLGR 94
KELAA pfam19311
KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins ...
919-950 2.02e-08

KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins. It has a conserved KELAA sequence for which it is named.


:

Pssm-ID: 466035  Cd Length: 32  Bit Score: 50.57  E-value: 2.02e-08
                          10        20        30
                  ....*....|....*....|....*....|..
gi 149393138  919 LRVKNAVYCAVIFPEFLKELAAISQAHAVTSP 950
Cdd:pfam19311   1 ERHKNLLEAAIVLEEFCKELAAIAFVKSHHSV 32
PHA03321 super family cl33724
tegument protein VP11/12; Provisional
459-590 4.69e-03

tegument protein VP11/12; Provisional


The actual alignment was detected with superfamily member PHA03321:

Pssm-ID: 223041 [Multi-domain]  Cd Length: 694  Bit Score: 40.71  E-value: 4.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138 459 RCCRHHAPSPPRPEHASWARGPGSPSV--DSSSVTTVPRPSTPSrlALFLRQQSLGGSESPGPAPCSPglsASPASSPGR 536
Cdd:PHA03321 372 RFCRTTAPLFPTMTASSWARMERSIKAwfEAALATELFRTGVPS--EHYEASLRLLSSRQPPGAPAPR---RDNDPPPPP 446
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 149393138 537 RPTPAEEPGELEDNYLEYLREARRGVDRCVRACRTWSAPYDgerPSPEPSPFGS 590
Cdd:PHA03321 447 RARPGSTPACARRARAQRARDAGPEYVDPLGALRRLPAGAA---PPPEPAAAPS 497
 
Name Accession Description Interval E-value
RAI16-like pfam10257
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a ...
97-426 1.23e-110

Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a family of proteins described as retinoic acid-induced protein 16-like proteins. The exact function is not known. The proteins are found from worms to humans.


Pssm-ID: 370927  Cd Length: 357  Bit Score: 345.85  E-value: 1.23e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138   97 LEFALHEDLLTRVLTWQLQwdELGDGVeerRAEQLKLFEMLVSEARQPLLRHGPVREALLTLLDACGRPVPssPALDEGL 176
Cdd:pfam10257   2 LEYLLQHKILETLCTLGKA--DYPPGM---KQEVLKFYNKLLSHERQPLLHHINVHRPLQKLLRSCGEPVG--SDVEKEL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  177 VLLLSQLCVCVAQEPSLLEFFLQP----------------PPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMAL 240
Cdd:pfam10257  75 VQLLFGLCVKLRQDPSLLNFFFENksdqqraellvnpsveFAGATGKEDFNLFSLLLPLVHREGRLGVFAREGLLLLMSL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  241 SAGSPTVGRYIADHSYFCPVLATGLSALYSSLPRKIE---VPGDDW---HCLRREDWLGVP---ALALFMSSLEFCNAVI 311
Cdd:pfam10257 155 ASRSPTLATYLIESSDLCPLLATGLGALYSLLPTSLPaptISSIDWrldHSIAPEDLATFPgkrALDSFLSWLDFCNDLI 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  312 QVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLR-------TFLRFLLLHRHDTHTI 384
Cdd:pfam10257 235 QVAHSEVADALLDAIYEGFLVPVLYPSLLQTSEGSILAVTAYLDRILRSITSPALLQeflsfllGEEKSPETSDDDGHPL 314
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 149393138  385 LDTLVARIGSNS-RLCMVSLSLFRTLLNLSCEDVLLQLVLRYL 426
Cdd:pfam10257 315 RDTLIERCNHLSdELSIVTLRLFETLLQLPCEDILLDLVLRNL 357
DUF5917 pfam19314
Family of unknown function (DUF5917); This short presumed domain is found close to the ...
738-831 4.18e-40

Family of unknown function (DUF5917); This short presumed domain is found close to the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins.


Pssm-ID: 466037  Cd Length: 94  Bit Score: 142.71  E-value: 4.18e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  738 TGPFMAVLFAKLENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIENFAASQEDF 817
Cdd:pfam19314   1 EGPFLRMLFNKLENLLSQSYEVNLQLTGVISRLASYPQPLLHSYLLNPSLPLQPSVRSLYTVLSSLKEEIEERAASIPDF 80
                          90
                  ....*....|....
gi 149393138  818 PALLSKAKKYLIAR 831
Cdd:pfam19314  81 DALLRRARKRLLGR 94
KELAA pfam19311
KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins ...
919-950 2.02e-08

KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins. It has a conserved KELAA sequence for which it is named.


Pssm-ID: 466035  Cd Length: 32  Bit Score: 50.57  E-value: 2.02e-08
                          10        20        30
                  ....*....|....*....|....*....|..
gi 149393138  919 LRVKNAVYCAVIFPEFLKELAAISQAHAVTSP 950
Cdd:pfam19311   1 ERHKNLLEAAIVLEEFCKELAAIAFVKSHHSV 32
PHA03321 PHA03321
tegument protein VP11/12; Provisional
459-590 4.69e-03

tegument protein VP11/12; Provisional


Pssm-ID: 223041 [Multi-domain]  Cd Length: 694  Bit Score: 40.71  E-value: 4.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138 459 RCCRHHAPSPPRPEHASWARGPGSPSV--DSSSVTTVPRPSTPSrlALFLRQQSLGGSESPGPAPCSPglsASPASSPGR 536
Cdd:PHA03321 372 RFCRTTAPLFPTMTASSWARMERSIKAwfEAALATELFRTGVPS--EHYEASLRLLSSRQPPGAPAPR---RDNDPPPPP 446
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 149393138 537 RPTPAEEPGELEDNYLEYLREARRGVDRCVRACRTWSAPYDgerPSPEPSPFGS 590
Cdd:PHA03321 447 RARPGSTPACARRARAQRARDAGPEYVDPLGALRRLPAGAA---PPPEPAAAPS 497
 
Name Accession Description Interval E-value
RAI16-like pfam10257
Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a ...
97-426 1.23e-110

Retinoic acid induced 16-like protein; This is the conserved N-terminal 450 residues of a family of proteins described as retinoic acid-induced protein 16-like proteins. The exact function is not known. The proteins are found from worms to humans.


Pssm-ID: 370927  Cd Length: 357  Bit Score: 345.85  E-value: 1.23e-110
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138   97 LEFALHEDLLTRVLTWQLQwdELGDGVeerRAEQLKLFEMLVSEARQPLLRHGPVREALLTLLDACGRPVPssPALDEGL 176
Cdd:pfam10257   2 LEYLLQHKILETLCTLGKA--DYPPGM---KQEVLKFYNKLLSHERQPLLHHINVHRPLQKLLRSCGEPVG--SDVEKEL 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  177 VLLLSQLCVCVAQEPSLLEFFLQP----------------PPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMAL 240
Cdd:pfam10257  75 VQLLFGLCVKLRQDPSLLNFFFENksdqqraellvnpsveFAGATGKEDFNLFSLLLPLVHREGRLGVFAREGLLLLMSL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  241 SAGSPTVGRYIADHSYFCPVLATGLSALYSSLPRKIE---VPGDDW---HCLRREDWLGVP---ALALFMSSLEFCNAVI 311
Cdd:pfam10257 155 ASRSPTLATYLIESSDLCPLLATGLGALYSLLPTSLPaptISSIDWrldHSIAPEDLATFPgkrALDSFLSWLDFCNDLI 234
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  312 QVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLR-------TFLRFLLLHRHDTHTI 384
Cdd:pfam10257 235 QVAHSEVADALLDAIYEGFLVPVLYPSLLQTSEGSILAVTAYLDRILRSITSPALLQeflsfllGEEKSPETSDDDGHPL 314
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 149393138  385 LDTLVARIGSNS-RLCMVSLSLFRTLLNLSCEDVLLQLVLRYL 426
Cdd:pfam10257 315 RDTLIERCNHLSdELSIVTLRLFETLLQLPCEDILLDLVLRNL 357
DUF5917 pfam19314
Family of unknown function (DUF5917); This short presumed domain is found close to the ...
738-831 4.18e-40

Family of unknown function (DUF5917); This short presumed domain is found close to the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins.


Pssm-ID: 466037  Cd Length: 94  Bit Score: 142.71  E-value: 4.18e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  738 TGPFMAVLFAKLENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIENFAASQEDF 817
Cdd:pfam19314   1 EGPFLRMLFNKLENLLSQSYEVNLQLTGVISRLASYPQPLLHSYLLNPSLPLQPSVRSLYTVLSSLKEEIEERAASIPDF 80
                          90
                  ....*....|....
gi 149393138  818 PALLSKAKKYLIAR 831
Cdd:pfam19314  81 DALLRRARKRLLGR 94
KELAA pfam19311
KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins ...
919-950 2.02e-08

KELAA motif; This short motif is found at the C-terminus of FHIP proteins, FAM160B proteins and UPF0518 family proteins. It has a conserved KELAA sequence for which it is named.


Pssm-ID: 466035  Cd Length: 32  Bit Score: 50.57  E-value: 2.02e-08
                          10        20        30
                  ....*....|....*....|....*....|..
gi 149393138  919 LRVKNAVYCAVIFPEFLKELAAISQAHAVTSP 950
Cdd:pfam19311   1 ERHKNLLEAAIVLEEFCKELAAIAFVKSHHSV 32
PHA03321 PHA03321
tegument protein VP11/12; Provisional
459-590 4.69e-03

tegument protein VP11/12; Provisional


Pssm-ID: 223041 [Multi-domain]  Cd Length: 694  Bit Score: 40.71  E-value: 4.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138 459 RCCRHHAPSPPRPEHASWARGPGSPSV--DSSSVTTVPRPSTPSrlALFLRQQSLGGSESPGPAPCSPglsASPASSPGR 536
Cdd:PHA03321 372 RFCRTTAPLFPTMTASSWARMERSIKAwfEAALATELFRTGVPS--EHYEASLRLLSSRQPPGAPAPR---RDNDPPPPP 446
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 149393138 537 RPTPAEEPGELEDNYLEYLREARRGVDRCVRACRTWSAPYDgerPSPEPSPFGS 590
Cdd:PHA03321 447 RARPGSTPACARRARAQRARDAGPEYVDPLGALRRLPAGAA---PPPEPAAAPS 497
PHA03247 PHA03247
large tegument protein UL36; Provisional
467-587 7.83e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 40.31  E-value: 7.83e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 149393138  467 SPPRPEHASWARGPGSPSVDSSSVT--TVPRPSTPSRLALFLRQQSLGGSESPGPAPCSPGLSASPAsSPGRRPTPAEEP 544
Cdd:PHA03247 2877 APARPPVRRLARPAVSRSTESFALPpdQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPL-APTTDPAGAGEP 2955
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 149393138  545 -GELEDNYLEYLREARrgvdrcVRACRTWSAPYDGERPSPEPSP 587
Cdd:PHA03247 2956 sGAVPQPWLGALVPGR------VAVPRFRVPQPAPSREAPASST 2993
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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