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Conserved domains on  [gi|149192851|ref|NP_001092253|]
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ribonuclease P protein subunit p14 [Homo sapiens]

Protein Classification

Rpp14/Pop5 family protein( domain architecture ID 10487177)

Rpp14/Pop5 family protein similar to ribonuclease P protein subunit p14 and ribonuclease P/MRP protein subunit POP5, which are components of ribonucleoprotein complexes that generate mature tRNA molecules by cleaving their 5'-ends

Gene Ontology:  GO:0030677|GO:0001682|GO:0033204|GO:0004526
PubMed:  16998185|20627997

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RNase_P_Rpp14 pfam01900
Rpp14/Pop5 family; tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule ...
 35-108 8.33e-08

Rpp14/Pop5 family; tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule associated with at least eight protein subunits, hPop1, Rpp14, Rpp20, Rpp25, Rpp29, Rpp30, Rpp38, and Rpp40. This protein is known as Pop5 in eukaryotes.


:

Pssm-ID: 460379  Cd Length: 102  Bit Score: 46.73  E-value: 8.33e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 149192851   35 LNAAQFKQLLISAVKDLFGEVDAALPLDILT---YEEKTLSAILRICSSGLVKLWSSLTLLGSYKGKKCAFRVIQVS 108
Cdd:pfam01900  15 LSRKSLLKAIRDSVQELFGDFGAGAAGPSLQvkyFSPATGTGIIRCRREHYRLVWAALTLITSIGGRPVIFRVLHVS 91
 
Name Accession Description Interval E-value
RNase_P_Rpp14 pfam01900
Rpp14/Pop5 family; tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule ...
 35-108 8.33e-08

Rpp14/Pop5 family; tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule associated with at least eight protein subunits, hPop1, Rpp14, Rpp20, Rpp25, Rpp29, Rpp30, Rpp38, and Rpp40. This protein is known as Pop5 in eukaryotes.


Pssm-ID: 460379  Cd Length: 102  Bit Score: 46.73  E-value: 8.33e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 149192851   35 LNAAQFKQLLISAVKDLFGEVDAALPLDILT---YEEKTLSAILRICSSGLVKLWSSLTLLGSYKGKKCAFRVIQVS 108
Cdd:pfam01900  15 LSRKSLLKAIRDSVQELFGDFGAGAAGPSLQvkyFSPATGTGIIRCRREHYRLVWAALTLITSIGGRPVIFRVLHVS 91
 
Name Accession Description Interval E-value
RNase_P_Rpp14 pfam01900
Rpp14/Pop5 family; tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule ...
 35-108 8.33e-08

Rpp14/Pop5 family; tRNA processing enzyme ribonuclease P (RNase P) consists of an RNA molecule associated with at least eight protein subunits, hPop1, Rpp14, Rpp20, Rpp25, Rpp29, Rpp30, Rpp38, and Rpp40. This protein is known as Pop5 in eukaryotes.


Pssm-ID: 460379  Cd Length: 102  Bit Score: 46.73  E-value: 8.33e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 149192851   35 LNAAQFKQLLISAVKDLFGEVDAALPLDILT---YEEKTLSAILRICSSGLVKLWSSLTLLGSYKGKKCAFRVIQVS 108
Cdd:pfam01900  15 LSRKSLLKAIRDSVQELFGDFGAGAAGPSLQvkyFSPATGTGIIRCRREHYRLVWAALTLITSIGGRPVIFRVLHVS 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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