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Conserved domains on  [gi|116284402|ref|NP_001070817|]
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zinc finger protein 682 isoform 2 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
KRAB super family cl42959
krueppel associated box;
1-32 2.51e-13

krueppel associated box;


The actual alignment was detected with superfamily member smart00349:

Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 64.54  E-value: 2.51e-13
                           10        20        30
                   ....*....|....*....|....*....|..
gi 116284402     1 MLENYRNLVSLGLTVSKPELISRLEQRQEPWN 32
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
207-413 1.42e-08

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.01  E-value: 1.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 207 NWCSSLTKHKRIHTgekPYKCEECGKAFHWCSPFVRHK--KIHTGE--KPYTC--EDCGRAFNRHSHLTKHKTIHTGKKP 280
Cdd:COG5048  275 PNESDSSSEKGFSL---PIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISP 351
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 281 YKCKecgkafnhcslLTIHERTHTGEKPYKCEECgkafnsssilTEHKVIHSGEKPYKCE--KCDKVFKRFSYLTKHKRI 358
Cdd:COG5048  352 AKEK-----------LLNSSSKFSPLLNNEPPQS----------LQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIIT 410
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 116284402 359 HTGEKP--YKCEECGKAFNWSSILTEHKRIHTGEKPYNCEECGKaFNRCSHLTRHKK 413
Cdd:COG5048  411 HLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
183-207 6.60e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.60e-04
                          10        20
                  ....*....|....*....|....*
gi 116284402  183 YLTKHKRIHTGEKPYKCEECGKAFN 207
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 super family cl25788
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
81-216 1.42e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


The actual alignment was detected with superfamily member COG5189:

Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 1.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402  81 LRKDGENVGECKDQKEIYNGLNQC----LSTLPSKIFPYNkcvkvfSKSSNLNRENIRHTT-------EKLFKC--MQCG 147
Cdd:COG5189  285 LGFDYEFIHKSVGNKEIRGGISTGemidVRKLPCTNSSSN------GKLAHGGERNIDTPSrmlkvkdGKPYKCpvEGCN 358
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116284402 148 KVFKSHSGLSYHKIiHTEEKLCICEECGKTfkwfsyltKHKRIHTGEKPYKCEECGKAFNWCSSLTKHK 216
Cdd:COG5189  359 KKYKNQNGLKYHML-HGHQNQKLHENPSPE--------KMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
407-432 4.14e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.14e-03
                          10        20
                  ....*....|....*....|....*.
gi 116284402  407 HLTRHKKIHTAVKRYKCEECGKAFKR 432
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
1-32 2.51e-13

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 64.54  E-value: 2.51e-13
                           10        20        30
                   ....*....|....*....|....*....|..
gi 116284402     1 MLENYRNLVSLGLTVSKPELISRLEQRQEPWN 32
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
207-413 1.42e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.01  E-value: 1.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 207 NWCSSLTKHKRIHTgekPYKCEECGKAFHWCSPFVRHK--KIHTGE--KPYTC--EDCGRAFNRHSHLTKHKTIHTGKKP 280
Cdd:COG5048  275 PNESDSSSEKGFSL---PIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISP 351
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 281 YKCKecgkafnhcslLTIHERTHTGEKPYKCEECgkafnsssilTEHKVIHSGEKPYKCE--KCDKVFKRFSYLTKHKRI 358
Cdd:COG5048  352 AKEK-----------LLNSSSKFSPLLNNEPPQS----------LQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIIT 410
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 116284402 359 HTGEKP--YKCEECGKAFNWSSILTEHKRIHTGEKPYNCEECGKaFNRCSHLTRHKK 413
Cdd:COG5048  411 HLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
zf-H2C2_2 pfam13465
Zinc-finger double domain;
183-207 6.60e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.60e-04
                          10        20
                  ....*....|....*....|....*
gi 116284402  183 YLTKHKRIHTGEKPYKCEECGKAFN 207
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
351-375 6.60e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.60e-04
                          10        20
                  ....*....|....*....|....*
gi 116284402  351 YLTKHKRIHTGEKPYKCEECGKAFN 375
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
81-216 1.42e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 1.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402  81 LRKDGENVGECKDQKEIYNGLNQC----LSTLPSKIFPYNkcvkvfSKSSNLNRENIRHTT-------EKLFKC--MQCG 147
Cdd:COG5189  285 LGFDYEFIHKSVGNKEIRGGISTGemidVRKLPCTNSSSN------GKLAHGGERNIDTPSrmlkvkdGKPYKCpvEGCN 358
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116284402 148 KVFKSHSGLSYHKIiHTEEKLCICEECGKTfkwfsyltKHKRIHTGEKPYKCEECGKAFNWCSSLTKHK 216
Cdd:COG5189  359 KKYKNQNGLKYHML-HGHQNQKLHENPSPE--------KMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
407-432 4.14e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.14e-03
                          10        20
                  ....*....|....*....|....*.
gi 116284402  407 HLTRHKKIHTAVKRYKCEECGKAFKR 432
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
KRAB smart00349
krueppel associated box;
1-32 2.51e-13

krueppel associated box;


Pssm-ID: 214630 [Multi-domain]  Cd Length: 61  Bit Score: 64.54  E-value: 2.51e-13
                           10        20        30
                   ....*....|....*....|....*....|..
gi 116284402     1 MLENYRNLVSLGLTVSKPELISRLEQRQEPWN 32
Cdd:smart00349  30 MLENYSNLVSLGFQVPKPDLISQLEQGEEPWI 61
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
207-413 1.42e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 57.01  E-value: 1.42e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 207 NWCSSLTKHKRIHTgekPYKCEECGKAFHWCSPFVRHK--KIHTGE--KPYTC--EDCGRAFNRHSHLTKHKTIHTGKKP 280
Cdd:COG5048  275 PNESDSSSEKGFSL---PIKSKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISP 351
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 281 YKCKecgkafnhcslLTIHERTHTGEKPYKCEECgkafnsssilTEHKVIHSGEKPYKCE--KCDKVFKRFSYLTKHKRI 358
Cdd:COG5048  352 AKEK-----------LLNSSSKFSPLLNNEPPQS----------LQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIIT 410
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 116284402 359 HTGEKP--YKCEECGKAFNWSSILTEHKRIHTGEKPYNCEECGKaFNRCSHLTRHKK 413
Cdd:COG5048  411 HLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
260-442 3.18e-08

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 55.86  E-value: 3.18e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 260 RAFNRHSHLTKHKTIHTGK-KPYKCKECGKAFNHCSLLTIHERT--HTGE--KPYKCEE--CGKAFNSSSILTEHKVIHS 332
Cdd:COG5048  268 ASSQSSSPNESDSSSEKGFsLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCPYslCGKLFSRNDALKRHILLHT 347
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 333 GEKPYKC--EKCDKVF------KRFSYLTKHKRIHTGEKPYKCEECGKAFNWS-SILTEHKRIHTGEKPYNCE--ECGKA 401
Cdd:COG5048  348 SISPAKEklLNSSSKFspllnnEPPQSLQQYKDLKNDKKSETLSNSCIRNFKRdSNLSLHIITHLSFRPYNCKnpPCSKS 427
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 116284402 402 FNRCSHLTRHKKIHTAVKRYKCEECGKaFKRCSHLNEHKRV 442
Cdd:COG5048  428 FNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNHGKD 467
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
171-464 2.74e-06

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 49.69  E-value: 2.74e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 171 CEECGKTFKWFSYLTKHKRIHTGEKPYKC--EECGKAFNWCSSLTKHKRIHTG--------------EKPYKCEECGKAF 234
Cdd:COG5048   36 CPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNnpsdlnskslplsnSKASSSSLSSSSS 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 235 HWCSPF----------VRHKKIHTGEKPY-----TCEDCGRAFN-----------------------RHSHLTKHKTIHT 276
Cdd:COG5048  116 NSNDNNllsshslppsSRDPQLPDLLSISnlrnnPLPGNNSSSVntpqsnslhpplpanslskdpssNLSLLISSNVSTS 195
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 277 GKKPYKCKECG---KAFNHCSLLT---------IHERTHTGEKPYKCE---------------ECGKAFNSSSILTEHKV 329
Cdd:COG5048  196 IPSSSENSPLSssySIPSSSSDQNlensssslpLTTNSQLSPKSLLSQspsslsssdssssasESPRSSLPTASSQSSSP 275
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 330 IHSGE-------KPYKCEKCDKVFKRFSYLTKHKR--IHTGE--KPYKCEE--CGKAFNWSSILTEHKRIHTGEKPYNCE 396
Cdd:COG5048  276 NESDSssekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEK 355
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 397 EC------GKAFNRCSHLTRHKKIHTAVKRYKC---EECGKAFKR----CSHLNEHKRVQRGEksCKYKKCGEAFNHCSN 463
Cdd:COG5048  356 LLnssskfSPLLNNEPPQSLQQYKDLKNDKKSEtlsNSCIRNFKRdsnlSLHIITHLSFRPYN--CKNPPCSKSFNRHYN 433

                 .
gi 116284402 464 L 464
Cdd:COG5048  434 L 434
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
86-323 9.42e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 44.69  E-value: 9.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402  86 ENVGECKDQKEIYNGLNQCLSTLPSKI---FPYNKCVKVFSKSSNLNRENIRHTTEKLFKCM-QCGKVFKSHSGLSYHK- 160
Cdd:COG5048  231 TNSQLSPKSLLSQSPSSLSSSDSSSSAsesPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSkQCNISFSRSSPLTRHLr 310
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 161 -IIHTEEKL----CICEECGKTFKWFSYLTKHKRIHTGEKPYKCeecgkafNWCSSLTKHKRIHTGEKPykceecgkafh 235
Cdd:COG5048  311 sVNHSGESLkpfsCPYSLCGKLFSRNDALKRHILLHTSISPAKE-------KLLNSSSKFSPLLNNEPP----------- 372
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 236 wcSPFVRHKKIHTGEKPYTCE-DCGRAFNRHSHLTKHKTIHTGKKP--YKCKECGKAFNHCSLLTIHERTHTGEKPYKCE 312
Cdd:COG5048  373 --QSLQQYKDLKNDKKSETLSnSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCS 450
                        250
                 ....*....|.
gi 116284402 313 ECGKAFNSSSI 323
Cdd:COG5048  451 ILKSFRRDLDL 461
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
363-416 1.51e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 43.92  E-value: 1.51e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 116284402 363 KPYKCEECGKAFNWSSILTEHKRIHTGEKPYNC--EECGKAFNRCSHLTRHKKIHT 416
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHH 87
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
278-356 3.37e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 42.78  E-value: 3.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 278 KKPYKCKECGKAFNHCSLLTIHERTH----TGEKPYKCE--ECGKAFNSSSILTEHK-------------------VIHS 332
Cdd:COG5189  315 KLPCTNSSSNGKLAHGGERNIDTPSRmlkvKDGKPYKCPveGCNKKYKNQNGLKYHMlhghqnqklhenpspekmnIFSA 394
                         90       100
                 ....*....|....*....|....
gi 116284402 333 GEKPYKCEKCDKVFKRFSYLTKHK 356
Cdd:COG5189  395 KDKPYRCEVCDKRYKNLNGLKYHR 418
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
335-396 5.38e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 42.38  E-value: 5.38e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116284402 335 KPYKCEKCDKVFKRFSYLTKHKRIHTGEKPYKC--EECGKAFNWSSILTEHKRIHTGEKPYNCE 396
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNS 95
zf-H2C2_2 pfam13465
Zinc-finger double domain;
183-207 6.60e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.60e-04
                          10        20
                  ....*....|....*....|....*
gi 116284402  183 YLTKHKRIHTGEKPYKCEECGKAFN 207
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
351-375 6.60e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.97  E-value: 6.60e-04
                          10        20
                  ....*....|....*....|....*
gi 116284402  351 YLTKHKRIHTGEKPYKCEECGKAFN 375
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
307-364 9.89e-04

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.61  E-value: 9.89e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 307 KPYKCEECGKAFNSSSILTEHKVIHSGEKPYKC--EKCDKVFKRFSYLTKHKRIHTGEKP 364
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPS 91
zf-H2C2_2 pfam13465
Zinc-finger double domain;
211-234 1.02e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.02e-03
                          10        20
                  ....*....|....*....|....
gi 116284402  211 SLTKHKRIHTGEKPYKCEECGKAF 234
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
81-216 1.42e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.86  E-value: 1.42e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402  81 LRKDGENVGECKDQKEIYNGLNQC----LSTLPSKIFPYNkcvkvfSKSSNLNRENIRHTT-------EKLFKC--MQCG 147
Cdd:COG5189  285 LGFDYEFIHKSVGNKEIRGGISTGemidVRKLPCTNSSSN------GKLAHGGERNIDTPSrmlkvkdGKPYKCpvEGCN 358
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 116284402 148 KVFKSHSGLSYHKIiHTEEKLCICEECGKTfkwfsyltKHKRIHTGEKPYKCEECGKAFNWCSSLTKHK 216
Cdd:COG5189  359 KKYKNQNGLKYHML-HGHQNQKLHENPSPE--------KMNIFSAKDKPYRCEVCDKRYKNLNGLKYHR 418
zf-H2C2_2 pfam13465
Zinc-finger double domain;
267-292 1.60e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.60e-03
                          10        20
                  ....*....|....*....|....*.
gi 116284402  267 HLTKHKTIHTGKKPYKCKECGKAFNH 292
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
380-404 1.66e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.66e-03
                          10        20
                  ....*....|....*....|....*
gi 116284402  380 LTEHKRIHTGEKPYNCEECGKAFNR 404
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
296-320 1.69e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.69e-03
                          10        20
                  ....*....|....*....|....*
gi 116284402  296 LTIHERTHTGEKPYKCEECGKAFNS 320
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
333-413 2.88e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.09  E-value: 2.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 333 GEKPYKCE--KCDKVFKRfSYLTKHKRIHTGEKPYKCEecgkafNWSSIltEHKRIHTGEKPYNCEECGKAFNRCSHLTR 410
Cdd:COG5189  346 DGKPYKCPveGCNKKYKN-QNGLKYHMLHGHQNQKLHE------NPSPE--KMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416

                 ...
gi 116284402 411 HKK 413
Cdd:COG5189  417 HRK 419
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
251-322 2.96e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.06  E-value: 2.96e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 116284402 251 KPYTCEDCGRAFNRHSHLTKHKTIHTGKKPYKC--KECGKAFNHCSLLTIHERTHTGEKPYKCEECGKAFNSSS 322
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKA 105
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
278-342 3.81e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 39.68  E-value: 3.81e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 116284402 278 KKPYKCKECGKAFNHCSLLTIHERTHTGEKPYKC--EECGKAFNSSSILTEHKVIHSGEKPYKCEKC 342
Cdd:COG5048   31 PRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKS 97
zf-H2C2_2 pfam13465
Zinc-finger double domain;
407-432 4.14e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.14e-03
                          10        20
                  ....*....|....*....|....*.
gi 116284402  407 HLTRHKKIHTAVKRYKCEECGKAFKR 432
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
195-443 6.03e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 38.91  E-value: 6.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 195 KPYKCEECGKAFNWCSSLTKHKRIHTGEKPYKC--EECGKAFHWCSPFVRHKKIHTGEKPYTCEDCGR------------ 260
Cdd:COG5048   32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCsySGCDKSFSRPLELSRHLRTHHNNPSDLNSKSLPlsnskassssls 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 261 ----AFNRHSHLTKHKTIHTGKKP-------------YKCKECGKAFNHCSL----------------------LTIHER 301
Cdd:COG5048  112 ssssNSNDNNLLSSHSLPPSSRDPqlpdllsisnlrnNPLPGNNSSSVNTPQsnslhpplpanslskdpssnlsLLISSN 191
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 302 THTGEKPYKCEECGKAFNSSSILTEHKVIHSGEKPYKCEKCDKVF------------------------------KRFSY 351
Cdd:COG5048  192 VSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllsqspsslsssdssssasesprsslpTASSQ 271
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 116284402 352 LTKHKRIHTGE-----KPYKCEECGKAFNWSSILTEHKR--IHTGE--KPYNCEE--CGKAFNRCSHLTRHKKIHTAVKR 420
Cdd:COG5048  272 SSSPNESDSSSekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISP 351
                        330       340
                 ....*....|....*....|....*
gi 116284402 421 YKC--EECGKAFKRCSHLNEHKRVQ 443
Cdd:COG5048  352 AKEklLNSSSKFSPLLNNEPPQSLQ 376
zf-H2C2_2 pfam13465
Zinc-finger double domain;
242-264 8.32e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 8.32e-03
                          10        20
                  ....*....|....*....|...
gi 116284402  242 RHKKIHTGEKPYTCEDCGRAFNR 264
Cdd:pfam13465   4 RHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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